LOCUS       DBEJJV010000001       104516 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.001, whole genome shotgun sequence.
ACCESSION   DBEJJV010000001 DBEJJV010000000
VERSION     DBEJJV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 104516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 104516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..104516
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.001"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(24..176)
                     /locus_tag="ACL3GT_000001"
     CDS             complement(24..176)
                     /locus_tag="ACL3GT_000001"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515744.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVADRTDEVSSKHCFEVVDRTDEVS
                     NTYTAR"
     gene            247..903
                     /locus_tag="ACL3GT_000002"
     CDS             247..903
                     /locus_tag="ACL3GT_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HGR0515745.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWHNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGDLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRISVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGMVLDGQ
                     "
     gene            893..1216
                     /locus_tag="ACL3GT_000003"
                     /pseudo
     CDS             893..1216
                     /locus_tag="ACL3GT_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
     gene            1320..2150
                     /locus_tag="ACL3GT_000004"
     CDS             1320..2150
                     /locus_tag="ACL3GT_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0515746.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2304..3158
                     /locus_tag="ACL3GT_000005"
     CDS             2304..3158
                     /locus_tag="ACL3GT_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0515747.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3258..4631
                     /locus_tag="ACL3GT_000006"
     CDS             3258..4631
                     /locus_tag="ACL3GT_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HGR0515748.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYHTHIELVE
                     ELIRSYE"
     gene            4624..5685
                     /locus_tag="ACL3GT_000007"
     CDS             4624..5685
                     /locus_tag="ACL3GT_000007"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HGR0515749.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            5687..6379
                     /locus_tag="ACL3GT_000008"
     CDS             5687..6379
                     /locus_tag="ACL3GT_000008"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HGR0515750.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6408..6977)
                     /locus_tag="ACL3GT_000009"
     CDS             complement(6408..6977)
                     /locus_tag="ACL3GT_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0515751.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7112..7726
                     /locus_tag="ACL3GT_000010"
     CDS             7112..7726
                     /locus_tag="ACL3GT_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0515752.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7704..9374
                     /locus_tag="ACL3GT_000011"
     CDS             7704..9374
                     /locus_tag="ACL3GT_000011"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0515753.1"
                     /translation="MKNWRQNRMKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSR
                     EKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQ
                     LERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDF
                     KPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIF
                     HIGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLT
                     LRQTFANYQKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNI
                     HDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLR
                     NNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVE
                     NYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQ
                     ASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9386..10672
                     /locus_tag="ACL3GT_000012"
     CDS             9386..10672
                     /locus_tag="ACL3GT_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0515754.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10724..11257
                     /locus_tag="ACL3GT_000013"
     CDS             10724..11257
                     /locus_tag="ACL3GT_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515755.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11335..11805
                     /gene="nrdI"
                     /locus_tag="ACL3GT_000014"
     CDS             11335..11805
                     /gene="nrdI"
                     /locus_tag="ACL3GT_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HGR0515756.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12098..13360)
                     /locus_tag="ACL3GT_000015"
     CDS             complement(12098..13360)
                     /locus_tag="ACL3GT_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NRAMP family divalent metal transporter"
                     /protein_id="HGR0515757.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(13670..14128)
                     /locus_tag="ACL3GT_000016"
     CDS             complement(13670..14128)
                     /locus_tag="ACL3GT_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HGR0515758.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(14125..14565)
                     /locus_tag="ACL3GT_000017"
     CDS             complement(14125..14565)
                     /locus_tag="ACL3GT_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0515759.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            14921..16870
                     /gene="mutL"
                     /locus_tag="ACL3GT_000018"
     CDS             14921..16870
                     /gene="mutL"
                     /locus_tag="ACL3GT_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HGR0515760.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(17195..17662)
                     /gene="ribE"
                     /locus_tag="ACL3GT_000019"
     CDS             complement(17195..17662)
                     /gene="ribE"
                     /locus_tag="ACL3GT_000019"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009349 - riboflavin synthase complex
                     [Evidence IEA];
                     GO_function: GO:0000906 - 6,7-dimethyl-8-ribityllumazine
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HGR0515761.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(17663..18868)
                     /locus_tag="ACL3GT_000020"
     CDS             complement(17663..18868)
                     /locus_tag="ACL3GT_000020"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003935 - GTP cyclohydrolase II activity
                     [Evidence IEA];
                     GO_function: GO:0008686 -
                     3,4-dihydroxy-2-butanone-4-phosphate synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HGR0515762.1"
                     /translation="MEYRKIQETLEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLIERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(18888..19523)
                     /gene="ribE"
                     /locus_tag="ACL3GT_000021"
     CDS             complement(18888..19523)
                     /gene="ribE"
                     /locus_tag="ACL3GT_000021"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004746 - riboflavin synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HGR0515763.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(19508..20608)
                     /gene="ribD"
                     /locus_tag="ACL3GT_000022"
     CDS             complement(19508..20608)
                     /gene="ribD"
                     /locus_tag="ACL3GT_000022"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA];
                     GO_function: GO:0008835 -
                     diaminohydroxyphosphoribosylaminopyrimidine deaminase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HGR0515764.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(20743..20857)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            21014..21607
                     /gene="ruvA"
                     /locus_tag="ACL3GT_000023"
     CDS             21014..21607
                     /gene="ruvA"
                     /locus_tag="ACL3GT_000023"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HGR0515765.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            21617..22180
                     /locus_tag="ACL3GT_000024"
     CDS             21617..22180
                     /locus_tag="ACL3GT_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HGR0515766.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTETELEAMLENPAIIRNRAKLFATRANAQ
                     VLLQLQAEYGSFDAYLWSFVEGKIVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            22177..22854
                     /locus_tag="ACL3GT_000025"
     CDS             22177..22854
                     /locus_tag="ACL3GT_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0515767.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVRL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(22991..24022)
                     /locus_tag="ACL3GT_000026"
     CDS             complement(22991..24022)
                     /locus_tag="ACL3GT_000026"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HGR0515768.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(24277..24960)
                     /locus_tag="ACL3GT_000027"
     CDS             complement(24277..24960)
                     /locus_tag="ACL3GT_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HGR0515769.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILTSMFLWLLVFFATSFLPASLNPVLDPLPLAIIGVALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(24972..25916)
                     /locus_tag="ACL3GT_000028"
     CDS             complement(24972..25916)
                     /locus_tag="ACL3GT_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0515770.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            26048..28879
                     /gene="uvrA"
                     /locus_tag="ACL3GT_000029"
     CDS             26048..28879
                     /gene="uvrA"
                     /locus_tag="ACL3GT_000029"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HGR0515771.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            28872..29933
                     /locus_tag="ACL3GT_000030"
     CDS             28872..29933
                     /locus_tag="ACL3GT_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0515772.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            30065..30463
                     /gene="spx"
                     /locus_tag="ACL3GT_000031"
     CDS             30065..30463
                     /gene="spx"
                     /locus_tag="ACL3GT_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HGR0515773.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            30529..31098
                     /locus_tag="ACL3GT_000032"
     CDS             30529..31098
                     /locus_tag="ACL3GT_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP0191 family lipoprotein"
                     /protein_id="HGR0515774.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            31185..31451
                     /locus_tag="ACL3GT_000033"
     CDS             31185..31451
                     /locus_tag="ACL3GT_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HGR0515775.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            31455..31874
                     /gene="ruvX"
                     /locus_tag="ACL3GT_000034"
     CDS             31455..31874
                     /gene="ruvX"
                     /locus_tag="ACL3GT_000034"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HGR0515776.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            31890..32195
                     /locus_tag="ACL3GT_000035"
     CDS             31890..32195
                     /locus_tag="ACL3GT_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HGR0515777.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            32453..33703
                     /locus_tag="ACL3GT_000036"
     CDS             32453..33703
                     /locus_tag="ACL3GT_000036"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0515778.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKE
                     MEKTLLQTPAQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            33787..34242
                     /locus_tag="ACL3GT_000037"
     CDS             33787..34242
                     /locus_tag="ACL3GT_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0198 family lipoprotein"
                     /protein_id="HGR0515779.1"
                     /translation="MKLKRFTLSLASLASFSLLVACSQRAQQVQQPVAQQVQQPAQQN
                     TNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDGDRITLVVTGTTGTWTELESDG
                     DQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            34388..35920
                     /gene="cls"
                     /locus_tag="ACL3GT_000038"
     CDS             34388..35920
                     /gene="cls"
                     /locus_tag="ACL3GT_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HGR0515780.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            36178..37716
                     /locus_tag="ACL3GT_000039"
     CDS             36178..37716
                     /locus_tag="ACL3GT_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HGR0515781.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWGLHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            37836..40043
                     /gene="nrdD"
                     /locus_tag="ACL3GT_000040"
     CDS             37836..40043
                     /gene="nrdD"
                     /locus_tag="ACL3GT_000040"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HGR0515782.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            40055..40195
                     /locus_tag="ACL3GT_000041"
     CDS             40055..40195
                     /locus_tag="ACL3GT_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515783.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            40239..40745
                     /locus_tag="ACL3GT_000042"
     CDS             40239..40745
                     /locus_tag="ACL3GT_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515784.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            40738..41328
                     /gene="nrdG"
                     /locus_tag="ACL3GT_000043"
     CDS             40738..41328
                     /gene="nrdG"
                     /locus_tag="ACL3GT_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HGR0515785.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            41336..41953
                     /locus_tag="ACL3GT_000044"
     CDS             41336..41953
                     /locus_tag="ACL3GT_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0515786.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRYASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            42219..42527
                     /gene="rpsJ"
                     /locus_tag="ACL3GT_000045"
     CDS             42219..42527
                     /gene="rpsJ"
                     /locus_tag="ACL3GT_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HGR0515787.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            42744..43370
                     /gene="rplC"
                     /locus_tag="ACL3GT_000046"
     CDS             42744..43370
                     /gene="rplC"
                     /locus_tag="ACL3GT_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HGR0515788.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            43395..44018
                     /gene="rplD"
                     /locus_tag="ACL3GT_000047"
     CDS             43395..44018
                     /gene="rplD"
                     /locus_tag="ACL3GT_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HGR0515789.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            44018..44314
                     /locus_tag="ACL3GT_000048"
     CDS             44018..44314
                     /locus_tag="ACL3GT_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HGR0515790.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            44332..45165
                     /gene="rplB"
                     /locus_tag="ACL3GT_000049"
     CDS             44332..45165
                     /gene="rplB"
                     /locus_tag="ACL3GT_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HGR0515791.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            45269..45550
                     /gene="rpsS"
                     /locus_tag="ACL3GT_000050"
     CDS             45269..45550
                     /gene="rpsS"
                     /locus_tag="ACL3GT_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HGR0515792.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            45562..45906
                     /gene="rplV"
                     /locus_tag="ACL3GT_000051"
     CDS             45562..45906
                     /gene="rplV"
                     /locus_tag="ACL3GT_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HGR0515793.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            45919..46572
                     /gene="rpsC"
                     /locus_tag="ACL3GT_000052"
     CDS             45919..46572
                     /gene="rpsC"
                     /locus_tag="ACL3GT_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HGR0515794.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            46576..46989
                     /gene="rplP"
                     /locus_tag="ACL3GT_000053"
     CDS             46576..46989
                     /gene="rplP"
                     /locus_tag="ACL3GT_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HGR0515795.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            46999..47205
                     /gene="rpmC"
                     /locus_tag="ACL3GT_000054"
     CDS             46999..47205
                     /gene="rpmC"
                     /locus_tag="ACL3GT_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HGR0515796.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            47230..47490
                     /gene="rpsQ"
                     /locus_tag="ACL3GT_000055"
     CDS             47230..47490
                     /gene="rpsQ"
                     /locus_tag="ACL3GT_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HGR0515797.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            47516..47884
                     /gene="rplN"
                     /locus_tag="ACL3GT_000056"
     CDS             47516..47884
                     /gene="rplN"
                     /locus_tag="ACL3GT_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HGR0515798.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            47962..48267
                     /gene="rplX"
                     /locus_tag="ACL3GT_000057"
     CDS             47962..48267
                     /gene="rplX"
                     /locus_tag="ACL3GT_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HGR0515799.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            48291..48833
                     /gene="rplE"
                     /locus_tag="ACL3GT_000058"
     CDS             48291..48833
                     /gene="rplE"
                     /locus_tag="ACL3GT_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HGR0515800.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            48851..49120
                     /gene="rpsN"
                     /locus_tag="ACL3GT_000059"
     CDS             48851..49120
                     /gene="rpsN"
                     /locus_tag="ACL3GT_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HGR0515801.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            49405..49803
                     /gene="rpsH"
                     /locus_tag="ACL3GT_000060"
     CDS             49405..49803
                     /gene="rpsH"
                     /locus_tag="ACL3GT_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HGR0515802.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            49995..50531
                     /gene="rplF"
                     /locus_tag="ACL3GT_000061"
     CDS             49995..50531
                     /gene="rplF"
                     /locus_tag="ACL3GT_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HGR0515803.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            50615..50971
                     /gene="rplR"
                     /locus_tag="ACL3GT_000062"
     CDS             50615..50971
                     /gene="rplR"
                     /locus_tag="ACL3GT_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HGR0515804.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            50989..51483
                     /gene="rpsE"
                     /locus_tag="ACL3GT_000063"
     CDS             50989..51483
                     /gene="rpsE"
                     /locus_tag="ACL3GT_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HGR0515805.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            51497..51679
                     /gene="rpmD"
                     /locus_tag="ACL3GT_000064"
     CDS             51497..51679
                     /gene="rpmD"
                     /locus_tag="ACL3GT_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HGR0515806.1"
                     /translation="MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMITAVSHLVTVEEVN"
     gene            51824..52264
                     /gene="rplO"
                     /locus_tag="ACL3GT_000065"
     CDS             51824..52264
                     /gene="rplO"
                     /locus_tag="ACL3GT_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HGR0515807.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            52277..53587
                     /gene="secY"
                     /locus_tag="ACL3GT_000066"
     CDS             52277..53587
                     /gene="secY"
                     /locus_tag="ACL3GT_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HGR0515808.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            53738..54376
                     /locus_tag="ACL3GT_000067"
     CDS             53738..54376
                     /locus_tag="ACL3GT_000067"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HGR0515809.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            54493..54711
                     /gene="infA"
                     /locus_tag="ACL3GT_000068"
     CDS             54493..54711
                     /gene="infA"
                     /locus_tag="ACL3GT_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HGR0515810.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            54736..54852
                     /gene="rpmJ"
                     /locus_tag="ACL3GT_000069"
     CDS             54736..54852
                     /gene="rpmJ"
                     /locus_tag="ACL3GT_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HGR0515811.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            54870..55235
                     /gene="rpsM"
                     /locus_tag="ACL3GT_000070"
     CDS             54870..55235
                     /gene="rpsM"
                     /locus_tag="ACL3GT_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HGR0515812.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            55253..55636
                     /gene="rpsK"
                     /locus_tag="ACL3GT_000071"
     CDS             55253..55636
                     /gene="rpsK"
                     /locus_tag="ACL3GT_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HGR0515813.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            55679..56614
                     /locus_tag="ACL3GT_000072"
     CDS             55679..56614
                     /locus_tag="ACL3GT_000072"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HGR0515814.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            56626..57012
                     /gene="rplQ"
                     /locus_tag="ACL3GT_000073"
     CDS             56626..57012
                     /gene="rplQ"
                     /locus_tag="ACL3GT_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HGR0515815.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            57277..57543
                     /locus_tag="ACL3GT_000074"
     CDS             57277..57543
                     /locus_tag="ACL3GT_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HGR0515816.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            57553..58890
                     /locus_tag="ACL3GT_000075"
     CDS             57553..58890
                     /locus_tag="ACL3GT_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HGR0515817.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDETDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            59134..59826
                     /locus_tag="ACL3GT_000076"
     CDS             59134..59826
                     /locus_tag="ACL3GT_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0515818.1"
                     /translation="MVKVRLYLIRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(59929..61555)
                     /locus_tag="ACL3GT_000077"
                     /pseudo
     CDS             complement(59929..61555)
                     /locus_tag="ACL3GT_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(61545..62635)
                     /locus_tag="ACL3GT_000078"
                     /pseudo
     CDS             complement(61545..62635)
                     /locus_tag="ACL3GT_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62648..63754)
                     /locus_tag="ACL3GT_000079"
                     /pseudo
     CDS             complement(62648..63754)
                     /locus_tag="ACL3GT_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(63986..64210)
                     /locus_tag="ACL3GT_000080"
                     /pseudo
     CDS             complement(63986..64210)
                     /locus_tag="ACL3GT_000080"
                     /inference="COORDINATES: protein motif:HMM:NF024242.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(64258..65034)
                     /locus_tag="ACL3GT_000081"
     CDS             complement(64258..65034)
                     /locus_tag="ACL3GT_000081"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0043687 - post-translational protein
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HGR0515819.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            65156..65902
                     /locus_tag="ACL3GT_000082"
     CDS             65156..65902
                     /locus_tag="ACL3GT_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0515820.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            65915..66895
                     /locus_tag="ACL3GT_000083"
     CDS             65915..66895
                     /locus_tag="ACL3GT_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HGR0515821.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            67090..67410
                     /locus_tag="ACL3GT_000084"
     CDS             67090..67410
                     /locus_tag="ACL3GT_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0515822.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            67456..67764
                     /locus_tag="ACL3GT_000085"
     CDS             67456..67764
                     /locus_tag="ACL3GT_000085"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0515823.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            67781..69079
                     /locus_tag="ACL3GT_000086"
     CDS             67781..69079
                     /locus_tag="ACL3GT_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0515824.1"
                     /translation="MAKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLLSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSWYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            69230..71668
                     /locus_tag="ACL3GT_000087"
     CDS             69230..71668
                     /locus_tag="ACL3GT_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HGR0515825.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIGGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKAALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            71687..72355
                     /locus_tag="ACL3GT_000088"
     CDS             71687..72355
                     /locus_tag="ACL3GT_000088"
                     /EC_number="4.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HGR0515826.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLVLAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            72373..73461
                     /locus_tag="ACL3GT_000089"
     CDS             72373..73461
                     /locus_tag="ACL3GT_000089"
                     /EC_number="1.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008888 - glycerol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HGR0515827.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            73916..76417
                     /gene="leuS"
                     /locus_tag="ACL3GT_000090"
     CDS             73916..76417
                     /gene="leuS"
                     /locus_tag="ACL3GT_000090"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HGR0515828.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            76611..77306
                     /locus_tag="ACL3GT_000091"
     CDS             76611..77306
                     /locus_tag="ACL3GT_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0515829.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            77318..77734
                     /locus_tag="ACL3GT_000092"
     CDS             77318..77734
                     /locus_tag="ACL3GT_000092"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515830.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(78549..78641)
                     /locus_tag="ACL3GT_000093"
     CDS             complement(78549..78641)
                     /locus_tag="ACL3GT_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HGR0515831.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            78775..79773
                     /gene="ruvB"
                     /locus_tag="ACL3GT_000094"
     CDS             78775..79773
                     /gene="ruvB"
                     /locus_tag="ACL3GT_000094"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HGR0515832.1"
                     /translation="MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEA
                     AKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELE
                     PGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYAHAGLTEIVERTADIFEMEITHEAASELALRSRGTPR
                     IANRLLKRVRDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGG
                     PVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            79754..80326
                     /locus_tag="ACL3GT_000095"
     CDS             79754..80326
                     /locus_tag="ACL3GT_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HGR0515833.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            80557..81315
                     /locus_tag="ACL3GT_000096"
     CDS             80557..81315
                     /locus_tag="ACL3GT_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HGR0515834.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            81324..82127
                     /locus_tag="ACL3GT_000097"
     CDS             81324..82127
                     /locus_tag="ACL3GT_000097"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004605 - phosphatidate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0016024 - CDP-diacylglycerol biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HGR0515835.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKIRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            82149..83408
                     /gene="rseP"
                     /locus_tag="ACL3GT_000098"
     CDS             82149..83408
                     /gene="rseP"
                     /locus_tag="ACL3GT_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HGR0515836.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRHKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            83421..85274
                     /locus_tag="ACL3GT_000099"
     CDS             83421..85274
                     /locus_tag="ACL3GT_000099"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HGR0515837.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPTLLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            85374..86753
                     /gene="bglA"
                     /locus_tag="ACL3GT_000100"
     CDS             85374..86753
                     /gene="bglA"
                     /locus_tag="ACL3GT_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HGR0515838.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            86945..88753
                     /gene="glmS"
                     /locus_tag="ACL3GT_000101"
     CDS             86945..88753
                     /gene="glmS"
                     /locus_tag="ACL3GT_000101"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HGR0515839.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            88872..89921
                     /locus_tag="ACL3GT_000102"
     CDS             88872..89921
                     /locus_tag="ACL3GT_000102"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HGR0515840.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(90021..93818)
                     /gene="spuA"
                     /locus_tag="ACL3GT_000103"
     CDS             complement(90021..93818)
                     /gene="spuA"
                     /locus_tag="ACL3GT_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HGR0515841.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWHLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDTHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVKIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQEASV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            94234..94647
                     /gene="rpsL"
                     /locus_tag="ACL3GT_000104"
     CDS             94234..94647
                     /gene="rpsL"
                     /locus_tag="ACL3GT_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HGR0515842.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            94667..95137
                     /gene="rpsG"
                     /locus_tag="ACL3GT_000105"
     CDS             94667..95137
                     /gene="rpsG"
                     /locus_tag="ACL3GT_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HGR0515843.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            95561..97642
                     /gene="fusA"
                     /locus_tag="ACL3GT_000106"
     CDS             95561..97642
                     /gene="fusA"
                     /locus_tag="ACL3GT_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HGR0515844.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            97746..102137
                     /locus_tag="ACL3GT_000107"
     CDS             97746..102137
                     /locus_tag="ACL3GT_000107"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HGR0515845.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGIEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNAAFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            102239..102502
                     /locus_tag="ACL3GT_000108"
     CDS             102239..102502
                     /locus_tag="ACL3GT_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HGR0515846.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            102495..102773
                     /locus_tag="ACL3GT_000109"
     CDS             102495..102773
                     /locus_tag="ACL3GT_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HGR0515847.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            102794..102946
                     /locus_tag="ACL3GT_000110"
     CDS             102794..102946
                     /locus_tag="ACL3GT_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515848.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            102968..104209
                     /locus_tag="ACL3GT_000111"
     CDS             102968..104209
                     /locus_tag="ACL3GT_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HGR0515849.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            104219..104449
                     /locus_tag="ACL3GT_000112"
     CDS             104219..104449
                     /locus_tag="ACL3GT_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0515850.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT        31096 a        19247 c        23318 g        30855 t
ORIGIN      
        1 actctcttca aaccacgtca gcttcacctt gccgtatatg tgttactgac ttcgtcagtt
       61 ctatccacaa cctcaaaaca gtgttttgag ctgacttcat cagttctatc tgcaacctca
      121 aaacagtgtt ttgagcaacc tgcggctagt ttcctagttt gctctttgat tttcattgag
      181 tattattaag acaatatgag gagaaagatg aaagaaaaag gattttagga gggggcgcag
      241 gcagccatgc caacggctct tggctatgtc agtatcggcc tggcctgtgg aattatcggt
      301 gcgccctatg tgacacctgt tgagatgggc ttgatgagtc tctttgttta tgctgggagt
      361 gcccagtttg ccatgttggc actgattgtg gttcaagctc ctgtggcagc tattgctatg
      421 acggtttttc taatcaattt gcgtctcttt ttgttgagct tacacgcatc gacttatttc
      481 cgtcatacca gtctttggca caatatcggt atgtctagta tcttgacaga tgagacctat
      541 ggcgttttga tgggcgaatt agcccataca gataaggtca atccgatgtg gatgcacggg
      601 aacaatctca acagctatgt ggcttggttt gtgggaacag tggtcggaac ggctctaggt
      661 gacctgttgc caaatccaga aatctttggt ttagattttg ccctggttgg gatgtttatc
      721 gggatttttg cttcgcaatt ccagatgatg caaagacgga tttctgtccg caatctgctc
      781 attatcttag cagttgttgc agtgtccttc tttttacttt tgacagtggt gtctcagtca
      841 ctagctgttc tgtttgcgac gctacttggt tgtagcatgg ggatggtttt agatggtcag
      901 taagtatctt ttattagcag ttattttctc tggtcttgtg acctggattc cccgtatgat
      961 tcccttcatc ttggtcaagt ataagggcct gcctacgatt gttgagcgtt ttttgaagtt
     1021 tttgcctgtt tccattatct ttgccttgat tctttcaaga gtagtgacag gtaaggttgg
     1081 gaaccttcct caaatcaaat gactggactt cttagcagtc tttccaacag cttgggtagc
     1141 ttttcgctac cgcaatctag tcggtacggt tctctttgga gtagtcttga ttgccgtctt
     1201 gcgtttggtc ttttaaataa gtcataaaga aaacttatca cagagataga tatcatataa
     1261 tggcgtaatt actttttttc tgataagatt ataaggtatt ctattttgga ggaaatgaca
     1321 tgaaaaaaat cgttaaatac tcatctcttg cagcccttgc tcttgttgct gcaggtgtgc
     1381 ttgcggcttg ctcaggtggt gctaagaaag aaggacaagc agctagcaag aaagaaatca
     1441 tcgttgcaac caatggatca ccaaggccat ttatctatga agaaaatggc gaattgactg
     1501 gttacgagat tgaagtcgtt cgcgctatct ttaaagattc tgacaaatat gatgtcaagt
     1561 ttgaaaagac agaatggtca ggtgtctttg ctggtcttga cgctgaccgt tacaatatgg
     1621 ctgtcaacaa tcttagctac actaaagaac gtgcggagaa atacctctat gccgcaccaa
     1681 ttgcccaaaa tcctaatgtc cttgtcgtga agaaagatga ctctagtatc aagtctctcg
     1741 atgatatcgg tggaaaatcg acggaagtcg ttcaagccac tacatcagct aagcagttag
     1801 aagcatacaa cgctgaacac acggacaacc caactatcct taactatact aaggcagatt
     1861 tccaacaaat catggtacgt ttgagcgatg gacaatttga ctataagatt tttgataaaa
     1921 tcggtgttga aacagtgatc aagaaccaag gtttggacaa cttgaaagtt atcgaacttc
     1981 caagcgacca acaaccgtac gtttacccac ttcttgctca gggtcaagat gagttgaaat
     2041 cgtttgtaga caaacgcatc aaagaacttt ataaagatgg aactcttgaa aaattgtcta
     2101 aacaattctt cggagacact tatctaccgg cagaagctga tattaaataa tttcttgaaa
     2161 tcatccattc tgagtaagat gggtggtttc tcagttttta gggatatagt tttaaactat
     2221 atatctgact atctaataac aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt
     2281 attattttta aggagaaaga atcatgaaaa tcaaaaaatg gcttggtcta gcagcccttg
     2341 ctacagtcgc aggtttggct cttgcagctt gcggaaactc agaaaagaaa gcagacaatg
     2401 caacaactat caaaatcgca actgttaacc gtagcggttc tgaagaaaaa cgttgggaca
     2461 aaatccaaga attggttaaa aaagacggaa ttaccttgga atttacagag ttcacagact
     2521 actcacaacc aaacaaagca actgctgatg gcgaagtaga tttgaacgct ttccaacact
     2581 ataacttctt gaataactgg aacaaagaaa acggaaaaga tcttgtagcg attgcagata
     2641 cttacatctc tccaatccgc ctttactcag gtttgaatgg aagtgccaac aagtacacta
     2701 aagtagaaga catcccagca aacggagaaa tcgctgtacc aaatgacgct acaaacgaaa
     2761 gccgtgcgct ttacttgctt caatcagctg gcttgattaa attggatgtt tctggaactg
     2821 ctcttgcaac agttgccaac atcaaagaaa atccaaagaa cttgaaaatc actgaattgg
     2881 acgctagcca aacagctcgt tcattgtcat cagttgacgc tgccgttgta aacaatacct
     2941 tcgttacaga agcaaaattg gactacaaga aagcactttt caaagaacaa gctgatgaaa
     3001 actcaaaaca atggtacaac atcattgttg cgaaaaaaga ttgggaaaca tcacctaagg
     3061 ctgatgctat caagaaagta atcgcagctt accacacaga tgacgtgaaa aaagttatcg
     3121 aagaatcatc agatggtttg gatcaaccag tttggtaata agaaacaggg aggtgggaga
     3181 gaaaattcca cctcttgctt ttgtatagag tatagattgt aaagaagact attcgttcat
     3241 agaaaggtag agagaatatg gtttttccta gcgaacaaga acagattgaa aaatttgaaa
     3301 aggatcatgt agtccaacat tattttgagg ttttgcgtac cttgatttct aagaaatcag
     3361 tctttgccca gcaggttgga ctcaaggaag tcgcaaatta tctgggtgag attttcaagc
     3421 gtgttggagc tgaagtggag attgatgaga gctatacagc gccctttgtc atggcacatt
     3481 tcaagagttc gcgtccagat gccaagacct tgattttcta taaccactat gacactgtgc
     3541 cagcggatgg ggatcaggtc tggacagagg atccttttac gctttcggtc cgcaatggct
     3601 tcatgtatgg gcgtggggtt gatgacgaca agggtcatat cacagctcgc ttgagtgctt
     3661 tgagaaaata tatgcagcac catgatgatt tacctgtcaa tatcagcttt atcatggagg
     3721 gagcggagga atcggcttca acagacctag ataagtattt ggaaaagcat gcagacaaac
     3781 tccgtggggc ggatttgttg gtctgggaac aagggaccaa aaatgccttg gagcagctgg
     3841 aaatttctgg tggcaataag gggattgtga cctttgatgc caaggtaaaa agcgctgatg
     3901 tggatatcca ctcgagttat ggtggtgttg tggaatcagc tccttggtat ctcctccaag
     3961 ccttacagtc tcttcgtgct gcggatggcc gtatcttggt tgaaggcttg tacgaagaag
     4021 tacaagagcc caatgaacga gaaatggcct tgctagaaac ttatggtcaa cgaaacccag
     4081 aggaagttag tcggatttat ggattggagt tgcctctctt acaggaggag cggatggcct
     4141 ttctaaaacg tttctttttc gagccagcgc ttaatatcga aggaatccag tctggttatc
     4201 aaggtcaggg tgttaagact attttacctg cagaagccag tgccaagcta gaggttcgtc
     4261 tggttccggg cctagaaccg catgatgttc tggaaaaaat tcggaaacag ctagacaaaa
     4321 atggctttga taaggtagaa ttatactata ccttgggaga gatgagctat cgaagcgata
     4381 tgagcgcacc agccattctc aatgtgatcg agttggccaa gaaattctat ccacagggcg
     4441 tttcagtctt gccgacgaca gcggggacag gacctatgca tacggtcttt gatgccctag
     4501 aggtaccaat ggttgcattc ggtctaggaa atgccaatag ccgagaccac ggtggagatg
     4561 aaaatgtgcg aatcgctgat tatcacaccc atatcgaatt agtagaggag ctgattagaa
     4621 gctatgagta gagatattat caagttagat cagatcgatg tgacttttca ccaaaagaag
     4681 agaaccatta cagcggttaa ggatgtgacc attcacatcc aagaagggga tatctacgga
     4741 atcgttggat attctggagc aggaaaatca acccttgtac gggtgattaa tctcttgcaa
     4801 aaaccatctg cagggaaaat taccattgac gacgatgtga tttttgacgg caaggtgacc
     4861 ttgacggcag agcagttgcg tcgtaaacgt caagatatcg gaatgatttt ccagcatttt
     4921 aacctgatga gccaaaagac agcagaggag aatgtagcct ttgcccttaa acactctgaa
     4981 ctcagcaagg aagaaaagaa ggctaaagta gctaagttgt tggacttggt tggtttggca
     5041 gatcgtgctg aaaactaccc ttcacaacta tctggagggc aaaaacagcg tgtggcaatt
     5101 gcgcgtgcct tggccaatga tccaaaaatc ttgatttcag acgagtcaac ttctgccctt
     5161 gatccgaaga caaccaagca gattttggcc ttgttgcaag atttgaacca aaaattaggc
     5221 ttgactgttg tcttgattac gcatgaaatg cagattgtca aagacattgc caaccgtgtg
     5281 gcggttatgc aggatgggca tttgattgaa gagggtagtg tgcttgaaat cttctcagac
     5341 cctaaacaac ctttgactca agactttatc tcaacagcta caggtattga cgaagccatg
     5401 gtcaaaatcg agaagcaaga aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa
     5461 ctcaagtacg ctggatcttc aacagacgag ccacttttga atgaattgta caagcattat
     5521 caagtaatgg ctaatattct ctatgggaat atcgaaatcc tcgatggtac tcctgttgga
     5581 gaattggtgg tggtcttgtc aggtgaaaaa gcagcgttgg caggtgccca agaagccatt
     5641 cgtcaagcag gcgtacagtt aaaagtattg aagggaggac agtaagatgg aatcattgat
     5701 tcaaacctat ttgccaaatg tctataagat gggttggtct ggtcaggcag gctggggaac
     5761 agctatctac ctaaccctct atatgacagt tctttccttc attatcggag gcttcttggg
     5821 gctagtggca ggtctctttc tcgtcttgac agcgccaggt ggtgtcttgg agaataaagt
     5881 cgtattctgg attttagaca aaattacctc aatttttcgt gcgattccct ttatcatcct
     5941 cttggcaatc ttgtcaccac tttctcactt gattgttaaa acaagtatcg ggccaaatgc
     6001 agcccttgtc ccactttctt ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt
     6061 cttggctgaa ttggatggcg gtgtcattga ggcggctcaa gcgagcggag cgactttctg
     6121 ggacatcgtg ggtgtttacc tatcagaagg tcttccagat ttgatccgtg tgacgactgt
     6181 gaccttgatt tcccttgttg gggaaacagc tatggccggt gcggttggag ctggtggtat
     6241 cggtaacgta gccatcgctt atggatttaa ccgctacaat cacgatgtga ccatcttggc
     6301 aaccattatt atcattttga ttatctttgc aatccaattc ttgggagatt tcttgactaa
     6361 gaaattgagt cataaataaa aagagccgcg tggctctttt taactgatca gattttctgt
     6421 gcaaattttt tactcaaggc ttgtccaatc aaggcaccca ctagggctcc gatgacaata
     6481 cttgcgataa atagaaggac agttccaggg tttggagcga ccatgatacg gtcgatatat
     6541 tcttgggatt ttcctcttgc cagaagagta gccatatagg ctttgggcgc aatccacata
     6601 agcaagattg gtcctgttgt actaaaggcg aaaataatga aagaaaggaa gttctttgtt
     6661 ttgtccttgt attttcctaa atgagctact tcatctgcta ggaggccaca gataattcca
     6721 ggaaggaagg aaccagcacc gtgtttagtt cccaagaaaa agagggcaat gacaaggccg
     6781 atagtggtaa tggctccaaa gcgcggaact tttgcgacta ggatcatata gacgctaccg
     6841 ccgacaaggg cagtaaaggc aggcgcataa aacatgtttc cagtttggtc aaagagattg
     6901 cccaaaagga caccaatccc catgcagagg aagtaaagaa ctgcaaaaag cagtgtagtt
     6961 aagatagatt tcttcatgaa ttgtctcctg ataatttttt cacaattctc attgtaccac
     7021 ggtttggtgg gattgtaaat ggatactaga agtttttgaa aacgcttgaa atatgatata
     7081 atggtttcat agttattttt aggggaatat catgggtaga tttttagact ttgtctttaa
     7141 tcgtttcttt ttagggatga ttgcgacagc cttcttttgg ctattaactt tagcaggagg
     7201 gattatcctt ggtctagcgc cggctagtgc caccttgatg agcttatatg cagaacatgg
     7261 ttatagcttt cgggaataca gtttgaagga ggcttggtct ctttacaagc aaaattttgt
     7321 ctcaagcaac ctgattttct atagcttttt aggtgtgggt ctagttttga cctatggttt
     7381 gtatctcttg gtgcaattgc ctcatcagac cattgttcat ttgattgcga cccttttgaa
     7441 tgtcctagta gttgccctga tctttttggc ttatacagta tctttaaaat tacaagttta
     7501 ttttgccttg tcctatcgaa atagtctcaa attatccttg attggcatct ttatgagtct
     7561 agcagctgtg gccaagattc tccttgggac tgtgctactt gtagcaattg gttactatat
     7621 gcctgccctg ctattttttg taggaattgg gatgtggcat ttctttatca gtgatatgtt
     7681 ggaacctgtc tatgaaatca tccatgaaaa attggcgaca aaatagaatg aagcagtttt
     7741 ggctacatac gcttctaaga acctatagtt cagtgatgat cattatcatt gcgagttttg
     7801 caatcttact ctcttacgct gactgggatt cacgtgaaaa ggaagcccag agagtagccc
     7861 agcgtgtaac tgctagaaca gtgagtgaaa ttgaatatta ccatagagag tcaacccaga
     7921 tagctcaggc tttagttgaa aaccaagctc gtattgaggg aatctataaa tactttagtc
     7981 ttagcatgcc agactatttt tactggcaat tagagcggaa agcttcgcct tatatatcag
     8041 tctctctgta tgaaaatgtt gatgacctct atgttcgaaa tgattttgta actggagtgg
     8101 ccattgcttt tcaagattac aaggaagtct atgtttctac taaagacaaa cgtagtggag
     8161 aaaaaatcag ggctgaggat ttcaaaccag caggaaatag ttttgccatt ccggtgtcag
     8221 atccagtgtc agatcaagat ttaggagtga tttacatctc cttggatcct gctgttttat
     8281 accatgccat tgataatact agaggtcata ctccgatggc agtaacagtg acctcacctt
     8341 ttgatacgga gatttttcat attggtgaga cagttgataa ggagagtgaa aattggctag
     8401 ttggcttaac ttctcatgga tatcaggttc aggtggcagt tcctaaaaac tttgttttac
     8461 aaggaacagt gactagctct gctttgattg tgggtttgag ccttctcttt attgtcattc
     8521 tttatctgac tttgaggcag acttttgcta attaccaaaa gcaggtagtg gatttagtag
     8581 aatccattca agtcattgct caaggcgaag aggggcgtcg gattgacatt tccgagaaag
     8641 atcaggaatt actcctaatc gcggagacga ccaatgatat gttggatcga ttggaaaaga
     8701 atatccatga tatttaccag ttagagctta gtcaaaaaga tgccaatatg cgagccttgc
     8761 aggcgcaaat caatcctcat tttatgtata atacgctgga gttcttgcgc atgtatgcag
     8821 ttatgcagag tcaagatgag ttggcagata tcatttatga attcagtagt ctcttgcgta
     8881 acaatatttc cgacgaaaga gagaccctcc tcaaacagga attagaattt tgccgtaaat
     8941 acagctatct ctgcatggtt cgctatccca agtccattgc ctatggtttc aagatagatc
     9001 cagagttaga gaatatgaag attcccaagt ttaccttgca accgctggta gaaaactatt
     9061 tcgcgcatgg tgttgaccac aggcggacag ataatgtgat tagcatcaag gctcttaaac
     9121 aggatggttt tgtggaaatt ttggtggtcg ataatggtag aggaatgtcg gctgaaaagt
     9181 tggcaaatat ccgagaaaaa ttaagtcaga gatattttga acaccaagcc agctacagtg
     9241 atcaaaggca gtctatcggg attgtcaatg tacacgagcg ttttgtgctc tattttggag
     9301 accgctatgc cattactata gagtctgcag agcaagccgg tgttcagtat cgtattacaa
     9361 ttcaagatga gtagaaaggg agaaaatgta taaagtatta ttagtagatg atgagtacat
     9421 ggtgacagaa ggtctgaagc gtttgattcc ctttgataag tgggatatgg aggttgtcgc
     9481 aacagccagt catgccgatg aagctctaga atatgttcag gaaaatcctg tcgatgtcat
     9541 catttccgat gtcaatatgc cagacaaaac agggcttgat atgattcggg agatgaaaga
     9601 gatcttacca gatgctgcct atatcctgct ctcaggttat caggagtttg attatgtaaa
     9661 aagagcaatg aaccttagtg tggtggacta tttggtcaag cctgttgata aggtagagct
     9721 gggaaatctg ctggagaaga ttgcaggtca gctcggcgag agagggaaga aaagtcagac
     9781 tcttagtcaa gaattagacg aggctggatt tgttagttat ttaggggata aggagaattg
     9841 gtggataggt ctatccaagg aaaaacaagg ttccttcacc attccctact atgtcttggg
     9901 ccaagactgg cagattttca tttctggcca acctctagat ggtttagtcg ttacaccttt
     9961 tgaagctcct tatcaagaac actttgaacg ctggaagctg aatgctgaga aaaccctctt
    10021 ttacggttct gtaaatttgc agcagtctga gagtctcttt gcctattacg aaccgattta
    10081 tagggttatc attcagggaa atctcaatca aatcgtagaa gagttaaatc tcttggagaa
    10141 ggtagttctt gaaaatacgc cgcgtgttcc gattactaaa cagcttttta ttcagtttgt
    10201 catggatgtt ttccatttat ttgaacatct caaagctgat gacctgacag acatcgtcaa
    10261 aaccattcat gctattcaat ccttcgatga attggtttct tatatcaagg aaactctgat
    10321 cagctttttc ggtcaatacc gtatgaatga aaatgtggtc agtgtgctgg aagtcattgg
    10381 tcgtgattac caaaaagagc tttccctcaa ggatatcagt aaggctctct ttatcaatcc
    10441 tgtttatcta gggcagttga ttaagcgtga aaccgattcg acttttgcag agttactaaa
    10501 caaacaacgt attaaggctg cccaacaact tttgctttca actagtgaca gcatcgaaga
    10561 tatttgttat gctgttggtt acagtaacct tggatatttc tataaagttt tccgaaaatt
    10621 gtgcggaaaa tcgccaaaag cctaccgaaa acaggtagaa actatactat aagatttgta
    10681 ttcctttaca aaaggtgcta taatattatc aggaggttct atcatgaaaa agaaaccaat
    10741 ttatctatgg gtcttgctaa tcttgtctgc ccttatttca gttccgtctc tgtttggaat
    10801 tgtgagtccc ttgcctagta aagaagccct tcgtgctgct cagaaacaag ttgcaggggt
    10861 caatgctcag caattagaag accagcttaa ttatacctat agagtagcag aagcatctca
    10921 ttctattttt aatgttgctt tgattgtgct atctactatt ttagtggtcg tagcgattgt
    10981 cttccttgtt cgtaaaaatt tgcaatatgc aaactatact tacgttggct atgttttgtt
    11041 agctattatt ggttcgattt atggctatgt tggtttacaa gacgctgtgc agttggttca
    11101 agatgagagc atgcgtttga cagtgagtat tggttcaaaa gctgttagca ttttctatat
    11161 cgtcatcaat gttctcttcc tagcccttgt cttctataag atgtggcgac aacagaaagc
    11221 cttggcagaa gaagaggaaa cagaagagct tacctaagta ttgacaaaaa agaactatca
    11281 agatacaatc ttggtagttg ttttttgatt atagataaaa tcatggaggt acatatgaag
    11341 acaatttctt tagtttatat tagtttgagt ggcaacactg aaagttttgt gacgcgcttg
    11401 aaagactatc tcttgtccca gtacaaaggg attgaggttc aaaagattca tatcaaggat
    11461 ttggtcaagg aaggcaaaaa tttctatgaa atggaccatc cctatgtcgc ttttttgccg
    11521 acctatctcg aaggtgggaa tggcgtggat aacggagatg ttgagatttt gacgacaccg
    11581 gtgggagatt ttattgccta tggtaacaat gctagtaagt gttttggtgt ggttgggtca
    11641 ggaaatcgta actttaataa ccaatactgc ctaacagcca agcaatacag tcaacgcttt
    11701 ggcttccctg tattggctga ctttgaaatg cgaggcatgc tggaagatat caaacatgtc
    11761 gcagctatta tcgcagattt gtatgagttg gaaaaggaga attaatactc aatgaaaatc
    11821 aaagagcaaa ctaggaagct agtcgcaggt tgctcaaagc acagctttga ggttgcagat
    11881 agagctgacg tggtttgaag agattctcga atagtataaa gttcttataa gatgtggttg
    11941 aagttgttca actgtttttt gagtataaac agtctttaag aacgtaaaaa agcataagtt
    12001 caggtcttca aaaccttgtt cttatgcttt ttatcataga aatatttgct gaattttctc
    12061 ttgaaatgaa accttatctt catctcgcgc ttgtccctta ccctgctttt ccgattgcga
    12121 gtgcgtagat aaagaagatg gcgaagccaa agaggaaaat caatcccgca atggcaaggt
    12181 gtttgagcca agaaggaaga tttttgtttt cacgtgttac caaggcgtaa ttcaaaagag
    12241 caaagaaagg tgttgtcagg aaagagccaa tcatggcaaa gcggagcatg gttgaaacct
    12301 gaccagcgaa gaacttgata atgacgatac cgatgatagc agtgatggtc atccagatgt
    12361 tcaaagattt acgattgtcc tctttttgac tgattagcag tcggagagat tcctgattaa
    12421 cgcgagaata gccatcgata acagttataa ctgttccaaa gatacagagg aaggcaataa
    12481 aggtaatcaa gtaacgggac cattcgccaa gaacagaggc atacatgccc acgaattgag
    12541 agatgtattt ggctgaagca gcttcaaccg cctgccctgt aggatactga atcagtgctc
    12601 ccagtgccac aaagaagacg gctaggatag ctgttccaat ataaccagtg ttaaagtcaa
    12661 acagagcgtc ttctgtgtta aagttgacgg tctttctctt ttcagctgac caaagtgaat
    12721 tgatggctga aatttcaata ggagccggca tccatcctag gagggagacg atgaagggca
    12781 gagctgccat ttgccaaggt gtcttctcga caaaatcaga actgtattct ggatgcttga
    12841 ccgccgcaat gataactgca agaacagtcg caatggttaa ggcagacata atccatttga
    12901 ccatgccgtc taaaagtttg tagcctccaa agagtagcat agcccaaatg attgcaacga
    12961 gaatgaggga ccactgagta atgctaagtc caatcattgg gaaggcactg gcgatgatag
    13021 ctgagcacag aatggcaaca ccagccgtgt tgaccatagc cgaaaagaca ttgagaataa
    13081 agaaaatcca gagatagagt tttccttttt cggcataacc ttcaaccaaa gtctttccag
    13141 tatcagctgt gtattcagca ccaaaacgga aaaatggata tttaaagaca ttggctaaga
    13201 tgaccaagag aagtagagac caaccgtaag aaccgccagc ttgagttgag gatacaatgt
    13261 gggaacctcc aacagcggca gttgccatta ggattccagg tcccattgct tttagcttgc
    13321 ttgcccaggt tgattgattt aaggaaatag cttgcgacat gataaatact cctttttgaa
    13381 ttttcagaat aatctgtata tgcaatctat attctacaaa aaattttgga aaaatgcaag
    13441 aatattttga aaaaagatag aaaatttaca aagaaaatct gaaataactg ttatgatata
    13501 gcagattgaa actagaatag tacacttttg cttctaaaac attgttagaa atcgatttga
    13561 ctgtcctgat tgatttatcc tgttcttatt tcatttcact atagtaaggt gcagcaggat
    13621 aaagcaaaac cgagaagttt ctttctcggt tttgcttatt atgaggttcc tattttctat
    13681 gctccaagag ttgattgatg tgatctactt ttttagcctc tcttttatag agaatagccc
    13741 agatgatgag atagacaatc gcaaactcga taatgagctg gaggtagaaa atccagtgga
    13801 aggggaacca accagcaaga gttgctagtg ggacaaagcc agccagcata aggaagaaat
    13861 gagtcagagt ggcacgaagc atgctccagt cacggctgaa taagcggttg ccaaagttga
    13921 agagcatacc gatggctgcc cagataagtg tgcagtagag caagaccagg gcaccgtgaa
    13981 cctgatgctg atccatcact tggccgatga gagagtaggg atttagtggt gcgtaggtat
    14041 ttggtgcata aatgagtgaa aagaggatgg agaggatgag gccgataaga acaccggcag
    14101 ctgcatcgtg aaatacttgt tttttcatag ttctaatttc tccttgatgg tttttagata
    14161 acggcgtgaa gagtaggtga agctttcgtt tttcaagaaa atttctacca gaccgtttgg
    14221 cgtgagcttg aggtgagaga tggaatcgat attgatgatt tctgattggg aaatttggat
    14281 aaaattgctt ggcaagagtt taagaacctg atagagtcgc aaatcaatgc tgtaggtctg
    14341 actcgcggtt tctgctagaa ccttccgatt ctcgatatag aagcgctgaa tcttgccaat
    14401 ctcaactaga tagacctgat catcgatttt tcctttgatt ttttctcttt ggtccagatt
    14461 ttctgcgaac tcgatgactt tctggacttt ttcggtttct tgaggtgctt ggacaatcag
    14521 cttttcctcc tcgtaagtct cactaatctg tagttctact ttcataaatt tctctccttg
    14581 tttttcatac aaaattaatc tcacttcttg tacaccttta ttaatactct tcaaaaatct
    14641 cttcaaacca cgtcagcgtc gtcttgccgt aggatagttg ttgactttgt cagttttatc
    14701 tacaacctca aaacagtgtt ttgagctgtc tgcgtctagc tttctagttt gctctttgat
    14761 ttttattgag tataccacta ttttactccc tctggcaagg gactttgtct atgtggaggg
    14821 attgggctcc tatgtggtgg agtttttctg ttctttctga aatatggtat aatagcacta
    14881 attaatttct aggaaaatag atacagaaag gggctgaaag atgtctcata ttattgaatt
    14941 gccagagatg ctggcaaacc aaatcgcagc tggggaggtc attgaacgtc ctgccagtgt
    15001 ggttaaagag ttggtagaaa atgccattga cgcgggctct agtcagatta tcattgagat
    15061 tgaggaagct ggtctcaaga aggttcaaat cacggataac ggtcatggaa ttgcccacga
    15121 tgaggtggag ttggccctgc gtcgccatgc gaccagtaag ataaaaaatc aagcagatct
    15181 ctttcggatt cggacgcttg gttttcgtgg tgaagccttg ccttctattg cgtctgttag
    15241 tgtcttgact ctgttaacgg cggtggatgg tgctagtcat ggaaccaagt tagtcgcgcg
    15301 tgggggtgaa gttgaggaag tcatcccagc gactagtcct gtgggaacca aggtttgtgt
    15361 ggaggatctc tttttcaaca cgcctgcccg tctcaagtat atgaagagcc agcaagcgga
    15421 gttgtctcat atcattgata ttgtcaaccg tctgggcttg gcccatcctg agatttcttt
    15481 tagcttgatt agtgatggca aggaaatgac gcggacagca gggactggtc aattgcgcca
    15541 agcaatcgca gggatttacg gtttggtcag tgccaagaag atgattgaaa ttgagaactc
    15601 tgacctagat ttcgaaattt caggttttgt gtctttacct gagttgactc gggctaaccg
    15661 caattatatc agcctcttca tcaatggccg ttatatcaag aacttcctgc tcaatcgtgc
    15721 tattttggat ggtttcggaa gcaagcttat ggttggacgt tttccactgg ctgtcattca
    15781 catccatatc gacccttatc tagcggatgt caatgtgcat ccaactaagc aagaggtgcg
    15841 gatttccaag gaaaaagaac tgatgaccct ggtttcagaa gctattgcaa atagtctcaa
    15901 ggaacaaacc ttgattccag atgccttgga aaatcttgcc aaatcgaccg tgcgcaatcg
    15961 tgagaaggtg gagcaaacta ttctcccact caaagaaaat acgctctact atgagaaaac
    16021 tgagccgtca agacctagtc aaactgaagt agctgattat caggtagaat tgactgatga
    16081 agggcaggat ttgaccctgt ttgccaagga aaccttggac cgattgacca agccagcaaa
    16141 actgcatttt gcagagagaa agcctgctaa ctacgaccag ctagaccatc cagagttaga
    16201 tcttgctagc atcgataagg cttatgacaa actggagcga gaagaagcat ccagcttccc
    16261 agagttggag tttttcggac aaatgcacgg gacttatctc tttgcccaag ggcgagatgg
    16321 actttacatc atagatcagc acgctgctca ggaacgggtc aagtacgagg agtaccgtga
    16381 aagcattggc aatgttgacc agagtcagca gcaactccta gtgccctata tctttgaatt
    16441 tcctgcggat gatgccctgc gtctcaagga aagaatgcct ctcttagagg aagtgggcgt
    16501 ctttctagca gagtacggag aaaatcaatt tattctacgt gaacatccta tttggatggc
    16561 agaagaagag attgaatcag gcatctatga gatgtgcgac atgctccttt tgaccaagga
    16621 agtttctatc aagaaatacc gagcagagct ggctatcatg atgtcttgca agcgatctat
    16681 caaggccaat catcgtattg atgatcattc agctagacaa ctcctctatc agctttctca
    16741 atgtgacaat ccctataact gtcctcacgg acgtcctgtt ttggtgcatt ttaccaagtc
    16801 ggatatggaa aagatgttcc gacgtattca ggaaaatcac accagtctcc gtgagttggg
    16861 gaaatattaa aagtataaaa aagtctggga aaaattttca aaatcagaaa aacgcataaa
    16921 atcaggtgtt caaaaacctt gattttatgc gttttatcat ggaaatagtt acttcatgtt
    16981 ttcctaattc ttttcgaaac tctttttaaa ccacgtcagt tttatcagta atctcaaaac
    17041 agtgttttga gctaattttg ccagttttgt ctgtaacatc gaagttgtgt tttaccactc
    17101 tgcgactggt ttcctagttt gctctatgat tttcacagag tattaaattg cgattttgcc
    17161 aagtttcttt attcgtctaa aagtagagtc tgttctatgc gtctaatgta cgaattaggt
    17221 tgaccatttc aatagctcct tgtgcacact cagaaccctt atttcctgct ttggtaccag
    17281 ctcgttctat ggcttgttca attgtatctg tcgttagcac accaaacata acaggaattt
    17341 cgctatttaa actgatttgg gcgattccct tagatacctc gctacataca taatcataat
    17401 gacttgtatt ccctctaatg acagctccca agcagataat tgcatcatat tttttacttt
    17461 ttgccatttt tgatgcaatc agtggtattt caaaagctcc tggaacccag gctacctcta
    17521 tatctttctc gtttacattc tctcttttga gattatctag tgctccagat aataattttg
    17581 aagttataaa ttcattaaat ctcgctacaa caatacctat tttaatattg tttgctacta
    17641 aattaccttc ataagtgttc atttattttt cctccatatt taaaatgtga cccattcgat
    17701 ttttctttgt ttctaaataa aaactatcgt aaggattggc ttctatttcg attgatattc
    17761 tactggaaat ggtaattcca tatttttcta actgttcaac cttgtcagga ttatttgtca
    17821 gtaaatgaag tgactgaagt cccagatctt taagcatttg tgctccaata tgatattctc
    17881 ttaaatcacc ttcaaagcct aatgcaagat tggcatcaag cgtatccatg ccttgatctt
    17941 gtaaatgata ggcttttaat ttattgataa gtccaattcc tcgtccctcc tgtcgcaagt
    18001 aaagtaagac acccgaacca ttctcaacaa tcattttcat agctttatcg aattgctgtc
    18061 cacaatcgca acgtaaagag cctaaaacat ctcctgttaa acattcggag tggacccgac
    18121 ataatacatt ggcttcatcc tctatgtttc ccataataag agcaagatga tgttccccat
    18181 ttagtttatc tatatagcta attgctttga aattaccgta tctagtaggc atattgacag
    18241 ttgaaactcg ttctatcagc tgatcatata cttttctata ttcttgtaat tctttgatgg
    18301 taattagtgg aatgttgtgt ttcttcgaga actgaattaa atcatctgtt ctcatcattt
    18361 tgccatcatg attcattatt tcacaacata ggccacactc ttttagtcca gctaatttta
    18421 ataaatcaac agttgcttct gtgtgtccat ttctttctag aacaccacct ttttttgcaa
    18481 ttaaaggaaa catgtgtcct ggcctgcgaa aatcagaggg tgttatatct tcagctacac
    18541 acatacgtgc ggtcagtcct ctttcctcgg cagaaatacc tgtggtcgtt tctttataat
    18601 caattgaaac tgtaaaagca gtcttatgat tatctgtatt gttttcaacc ataggtgaaa
    18661 gcattaattg attagctaaa ctttcgctca taggcataca aattaatcct ttggcataag
    18721 tagccataaa attaacattt tctgttgtag ctgcttgtgc agaacaaatt aagtctcctt
    18781 cattttctct atccttgtcg tctataacaa gaacaagtcg tcccttctgc aatgcttcta
    18841 atgtttcttg tatttttcga tattccattg actgattatc ctttctgcta aaatccattt
    18901 tgatataata gttccttaga tatttctgat tttggagagt tatccatcag tttttgcaca
    18961 tatttaccta agatatcatt ttcaagattt actgtactcc cgacttgttt acttttaaga
    19021 atggtttgtt tcaaggtatg agggataaca gatactgaaa agtttacttt ggagacttta
    19081 gcgacagtca gactaatgcc gtcaattgta atagatcctt tttcaactat taaatctaaa
    19141 atttcttttt gtgtgttgat ttgataccat acagcattat catctttttt tattgacgag
    19201 atttttcctg taccatcaat gtgtcctgta acgacgtgac ccccaagtcg accgttgata
    19261 gataaggctc tttctagatt cacctcactt ccatgtttta atagagtaag agctgttcga
    19321 ctccatgttt cattcattac atcaactgta aaggattgat gattgaaatg agtaactgta
    19381 agacagatac catttactgc tatactatcg cctaaatgga tatccgttaa tatttttgag
    19441 gctttaattg atagtttaca attacgagag tctttctgta ttctttcaac ttttccgatt
    19501 tcttcaatta ttcctgtgaa catggataaa tcacttcact ttctatgaga tagtcatttc
    19561 ctatttgaga aaaagcataa ggtttcaatc taatagcgtc atttggcaaa gaaatgcctt
    19621 cacctccgac aggaaacttg gcactgcctc caaaaatttt tggtgcaata tatattttca
    19681 gctcatcaac aatttgttgt tccaaagcac tccaattcat tagactgccc ccttctagaa
    19741 ctaggctatc aatctgcatg tttcctagat gttgcattaa actcgataag tctatatgat
    19801 tgcctttttt ctttatggaa agtatttcac agccatgatt ttgatatagc ttcattttat
    19861 ttttgtcttc agaggaagtg gcaatgtaag ttttaatatc atttgctgtt tttacgattt
    19921 tagaggtaag aggagttcgt aaatgtgtat cgcatatgat acggatagga tttttccctt
    19981 cctccaatct acatgtcagc aaaggatcgt cttgaataac agtattgact cccaccataa
    20041 ttgcactaac atggtgtcgt aactgatgca catgctttct tgcttcttct tcagtaatcc
    20101 atttggattg atttgtttta gtggctattt ttccatccat tgacattgca tatttcataa
    20161 aaacataggg tacatgctgg gtaatatact ttctaaaact ttttattaag ttaagacact
    20221 cattttctaa aattccaaca gtaacttgaa gattattttc ctcaagtatc tttactcctt
    20281 ttccagatac aataggatta cagtctaggc ttccaatgac tactcttgta ataccactat
    20341 cgattatagc atctatacag ggaggtgttt tcccgaagtg acaacagggt tcaagtgtta
    20401 cataaagcgt cgctccgaca ggggattctc tacagttttt aagagcattt ctctcagcat
    20461 gtgggccacc aaaaaactca tgataacctt gtccgatgat gtgattatct tttacaataa
    20521 ctgcgccgac cataggattg ggattgacgt aaccagcccc tttttgtgcc agttttattg
    20581 ctaatttcat atattttgaa tcgctcatct cactacctcc aaaaaaaata taccttgaat
    20641 aggggactac tcaaggcata caaaagaaaa cttatgcgat taacaaaaat actctgaaat
    20701 gacaagtaat catttcagag cacgcaaaaa gcacaaatat acttttatct tctttcatcc
    20761 agactatact gtcggctttg gaatttcacc aaatcatgcc tttcggctcg tgggctatac
    20821 caccggtagg gaattacacc ctgccctgaa gatagttatt caattacaga tgattatagt
    20881 acttaatttt gaatatgtca acagataaat accgattgtt tttgatatac tgtatttgtg
    20941 ataatcgatt ctcgctcctc ggataaagaa aatatgatat actagataaa cgaaataaga
    21001 gagaaggaat actatgtacg catatttaaa aggaatcatt accaaaatta ctgccaaata
    21061 cattgttctt gaaaccaatg gtattggtta tatcctgcat gtggccaatc cttatgccta
    21121 ttcaggtcag gttaatcagg aggatcagat ttatgtgcat caggttgtgc gtgaggacgc
    21181 ccatttgctt tatggatttc gctcagagga tgagaaaaag ctctttctta gtctgatttc
    21241 ggtctctggg attggtcctg tatcagctct tgctattatc gctgctgatg acaatgctgg
    21301 cttggttcaa gccattgaaa ccaagaacat cacctacttg accaagttcc ctaaaattgg
    21361 caagaaaaca gcccagcaga tggtgctgga cttggaaggc aaggtagtag ttgcaggaga
    21421 tgaccttcct gccaaggtcg cagtgcaagc aagtgctgaa aaccaagaat tggaagaagc
    21481 tatggaagcc atgttggctc tgggctacaa ggcaacagag ctcaagaaaa tcaagaaatt
    21541 ctttgaagga acgacagata cagctgagaa ctatatcaag tcggccctta aaatgttggt
    21601 caaataggag cagagaatga caaaacgttg ttcgtgggtc aagatgacaa acccgctcta
    21661 catcgcctat catgatgagg agtggggtca gcccctccat gatgaccaag cattgtttga
    21721 gttgttgtgt atggaaacct atcaggcagg cctgtcttgg gaaacggtac tcaacaaacg
    21781 ccaagctttc cgagaagcct ttcatagcta tcaaattcac tcagtcgcag agatgactga
    21841 gactgaattg gaagccatgc tggagaatcc agctatcatt cgaaatagag ccaagctttt
    21901 tgctacacgc gctaacgccc aagtccttct acagttacag gcagagtacg gctcttttga
    21961 tgcctatctt tggtcttttg ttgaggggaa aattgtcgtt aacgatgttc ctgattatcg
    22021 ccaagcgcca gctaaaacac ccttatctga gaaattagcc aaagatctca aaaaacgagg
    22081 cttcaagttc acaggcccag tcgccgtatt gtcttttcta caggctgcag ggctagttga
    22141 tgaccacgag aatgattgtg agtggaaagg tcttaaatga tgtctaacaa aaataaggga
    22201 attctgattt ttgcgattct ctatacagtc ctctttgtgt ttgatggcgt taaattgctg
    22261 gcttctttaa tgccatctgt cattgcaaat tatcttgttt atgtagtttt agctttatat
    22321 ggctccttct tgttcaagga tagattgatc caacaatgga aggagattag aaagactaaa
    22381 agaaaattct tctttggcgt cttaacagga tggctctttc tcattctgat gactgttgtc
    22441 tttgaatttg tatcagagat gttgaagcag tttgtgagac tagatggaca aggtctaaat
    22501 cagtctaata ttcaaagtac ctttcaagaa caaccactac tgatagctgt ttttgcttgt
    22561 gtcattggac ctctggtaga agaattattt ttccgtcagg tcttattgca ttacttgcag
    22621 gaacggttgc caggtttact aagcattatt ctggtaggac ttgtttttgc tctgactcat
    22681 atgcacagtt tggccctatc agagtggatt ggtgcagttg gttacttagg tggaggcctt
    22741 gccttttcta ttatttatgt gaaagaaaaa gagaatatct actatcccct acttgttcac
    22801 atgttaagca acagcctctc cttaatcatt ttagctatca gtatagtaaa atgaaatgag
    22861 aacaggacaa atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca
    22921 atatactgta atatgtgatg aaaatgccag taatgatacc gagaaaaaag ctgagaaact
    22981 tttcccagct ttatttgtta tagtcaaaga gaatgacttg ttcctgtgca tctacatgag
    23041 catggacccc aaagggtaca attgctcttg gagttgcgtg gccgacattc agattataga
    23101 caatcgggat attgctgtca atgatatcca atagtgcctc tttatagtcg tcatggaaag
    23161 tttcatccat aggttttccg accaagagtc cattgatgac cgcgaatatg ccagtgtcct
    23221 ttaaagttag caacatcttt ttgaagtctt ctggcttagg cttttcttcg cttgtttcga
    23281 gcaagaggat tttcccttcc cagtctgaca agtcagggaa aagtttgtat ttttggcaga
    23341 gttccgtgct atctgcgtat cgagagttgt caaagatatc gtagagggat tcgaggcaac
    23401 caccgaggat tttcccctcg aactgggcac ttccttgcaa caagtcaaaa cctgtatttg
    23461 tatgactgac acgaggtgtt cccagggccg tgggactaaa atcagttcgt tcctcatacc
    23521 aaacgtcact agggcggatt tctgaaattc ttcccgtctc aatcaattct ttaaagtagt
    23581 gaaggctata ggctagcatt tctttgtcta attcacaaat gtctgctaaa aaggattgac
    23641 cataaaaagt cttgattcct aatttatgca acatgaggtg gttcatggtt gtatccgaga
    23701 agccaagaaa aattttttgt ttgataacct tttggagttg gtcattttca aaaagataag
    23761 gtagcaagcg ataggtatcg tctccaccga tggcacatag gatcatgtcg atgctatcat
    23821 cagaaaaggc atgaatcaaa tcctctgcac gagcttcagg atggtccttg ataaagtcta
    23881 atccttttaa cgaatggggc aaaaagatgg gattgagtcc cagatccttg agacgttgga
    23941 tacccaagtc cacttcgtgt ttgacaaaat cctctccgat aatgccacta gataaactaa
    24001 caataccaat agtagaaacc atatctcatc ctcctagaaa tagattgagc ctattttatc
    24061 acaaaatata agagaaagct atgtgggatt tcagaagaat acttttaata ctcttcgaaa
    24121 atctcttcaa accacgtcag ttttatttgc aacctcaaag ctgtgctttg agcaacctgc
    24181 agctagcttc ctagtttgct ctttgatttt cattgagtat aactcaaaaa agtaagtgaa
    24241 aaagcaaccg cacctgcagt tgcttttatc gttttcttat tcttgatagc gtgttggtcc
    24301 tgcacttgca ctacggatat tcaagcgttt cttgagatag aagcgaaggg ctaggagggc
    24361 tactccaata atagctagtg gcaatggatc cagtactggg ttaaggctag ctggtaggaa
    24421 gcttgttgca aagaagacaa gcaaccaaag gaacatagaa gttaggataa ctagtacaga
    24481 tttccagaaa ggtggacgtt gactgcgatc catatctggt ccatagtatt ggtaaacaaa
    24541 gtagtacatc aagtagaagg caaatccacc aaccagtcca actaatagaa gagtaatcaa
    24601 tccatagccg aaagcttgat ctgccgcaaa gaaggttgtg agggcgctga caagggcaaa
    24661 gaggctagtg atgaaaagag ctgagtccat aatcatcagt tttggatcat cattttcttt
    24721 tggatgctct ttttcgtact gctctttgac agtgaagcta tgagcccaat gagttggtgc
    24781 gccgtatagg gaacgggcag ttgtaccttt agattgctcc tcaaggattt ggggaatgac
    24841 ttcctcaaaa atagtctgga tttcagcgtc tgttttccca tctttgatga attgttgggt
    24901 agcaatgtgg acaaactctt ggtttttctt agttaatttt tgtagatcaa tttgagacat
    24961 aggaactcct cttagaacca ttttttatgg atgagataga gagtgagcga gacactcata
    25021 gcaaaggcga taaagacgat taaccagaag gcatttggct ctccgtttag gggaatttca
    25081 ttatccttaa agttcatccc gtaggcagaa aagaccatgg ttgggatgga catgacgatg
    25141 gtcacaaggg ccaaggtttt catgatgttg ttctggttgt tagaaatgat agaggcaaag
    25201 gtctctgtca tagaatgcaa gacgtttcca taaatatctg ccatctcgat ggcctgttgg
    25261 gtttcaatca gggtgtcttc aagcaggtct tcgtcctcaa ggtatttctt gatattgctg
    25321 gttgaactgg tcaatttctt aatcacgcgc tcatttgttt tgagggaggc cttgaaatag
    25381 acgatagttt tttccaattc catgagctca atcaattctt cattacgagt tgattgatgc
    25441 agttgacttt cgatttgttc actcttgcgg tcgattgaac gaagggctgt taggtaaagc
    25501 tctgcattgc gataaagaat ttgaaagata aaacgtgaac gcatgaaggt atagaaatta
    25561 cgcaatcgac ggttgataaa gacatcaagg acaggtagtg gttccaaaca cgtagtgata
    25621 atggtttcct cagtgatgat aataccaagc gggatggtta cgtagtaggt gcggttattt
    25681 ctttcctccg tgaccggcac gtctacgata atcagggtat actcgtcttc aatggtaata
    25741 cgagacattt cttccgcatc gagcggtgct cgaaggtcgg caatatcaat atcgaaggtg
    25801 ttggcgattt cgagtgattc attttgagtc ggattgacga gattgatcca agtacccggt
    25861 tcaagcgtat cgatctcttt aaattcagtt gttgtagaga gaaaaacttg tttcatatcc
    25921 cttatccttt ctcatttttc agattttttc acactgtact attatactac aaaatcggcc
    25981 ttttgggtaa tagaatctca ctttttttgg tataatggta agcaataatg gactagaaag
    26041 aacaaagatg caagataaaa ttgtcattca tggggcgcgt gcccataatt taaaaaatat
    26101 tgatgtggag attccgcgag acaagttggt tgtcgtgact ggcttgtcag gttcagggaa
    26161 gtccagtctg gcttttgata ctctctatgc ggagggacaa cgtcgctatg tagagagttt
    26221 gtctgcctac gctcgtcagt tcttgggaaa tatggaaaaa ccagatgtag atgccattga
    26281 tggtctcagc ccagctattt ccatcgacca gaaaacgact agtaaaaatc ctcgctcgac
    26341 ggtgggaacg acgactgaaa tcaatgacta tctgcgtctc ctctacgcac gtgtggggac
    26401 gccttactgt atcaacggac atggagctat caatgcttct tctgtggagc aaatcgttga
    26461 taaggttttg gagttacctg aacgccagcg cttgcagatc ttggctcctg tcatccgcaa
    26521 gaaaaaaggc caacataaga gtgttatcga gaaggttcag aaagacgggt atgttcgtgt
    26581 tcgtgtggat ggggaagtct atgatgtgac cgaagtgcca gagttgtcta agagcaagca
    26641 acacaatatc gatgtcgtgg ttgaccgtat tgttatcaag gagggcattc gtagccgtct
    26701 ctttgattcc attgaagctg cccttcgtat cgcagaaggt tatgtgatta tcgacaccat
    26761 ggacgactct gagttgttgt tctctgagca ttatgcctgt ccagtttgtg gatttactgt
    26821 cccagagtta gaacctcgtc tcttctcttt caatgctccc tttggctctt gtagtgagtg
    26881 tgacggcttg gggattaagc tggaggtgga tactgatttg gtagtgccag atgccagcaa
    26941 aaccttacat gagggagcgc tggcaccttg gaatcctatc tcatccaact actatccaaa
    27001 catgttagag caggccatga aagtctttgg agtggctatg gataagcctt ttgaggacct
    27061 gtcagaagaa gataagaact tgattctcta cggctcagat ggtaaggaat tccatttcca
    27121 ttatgaaaat gaatttggtg gtgtgcgcga tatcgacatt ccgtttgagg gagttatcaa
    27181 taatatcaaa cgtcgttacc atgaaaccaa tagcgattac actcgcactc agatgcgtct
    27241 ctacatgaat gagctgacct gcggaacctg tcaaggctat cgtctcaatg accaggcctt
    27301 gtctgtccgt gtgggcggcc agcaagggcc acatattgga gaaatctcag acctgtctat
    27361 cgctgaccac ttggacttgg tgagccagtt aactttgtct gaaaatgaag ccatcattgc
    27421 tcgtcccatt ctcaaggaaa tcaaggatcg tttgaccttc cttaataatg tgggtcttaa
    27481 ctatctaacc ctgtcacgtt cagcaggaac cctttcaggt ggggaaagtc agcgcattcg
    27541 tttggcaacc cagattggtt ccaacctatc aggtgtcctc tatatcctag acgagccgtc
    27601 aatcggtctt caccagaggg acaatgaccg cctgattgcc agtctgaaaa agatgcgtga
    27661 cttgggcaat actcttatcg tggtggaaca cgacgaagat accatgcgtg aagctgatta
    27721 tctgattgac gttggtcctg gtgccggtgt ttttggtggt gagattgttg cagcaggtac
    27781 acctaagcaa gtggctcgca acagcaagtc tatcacaggt cagtacttgt caggcaaacg
    27841 tgtcatccca gtaccagaag agcgccgtgt cggaaatggt cgttttattg aagtgacagg
    27901 agcgcgtgag aacaacttgc aaaatgtcac ggctcgcttt ccactaggaa aatttatcgc
    27961 agtgacaggt gtgtcgggtt cagggaaatc gactctaatc aacagcattc tcaaaaaagc
    28021 cattgcccag aagctcaacc gtaattcaga caaacctggt aagtttaaga ctattacagg
    28081 gattgagcat gtcgaccgtt tgattgatat tgaccagagc cctatcggac ggacgccgag
    28141 gtctaaccca gctacctata caggagtttt tgacgatata cgtgaccttt ttgctcagac
    28201 aaatgaagcc aagattcgag gctacaagaa ggggcgcttc agtttcaacg tcaagggagg
    28261 tcgctgtgaa gcttgctcag gtgacgggat tatcaagatt gagatgcact tcttgccaga
    28321 tgtttatgtg gcttgtgaag tttgccacgg aacccgctat aacagtgaaa ccctagaagt
    28381 tcactacaag gaaaagaata tttcgcaggt cttggatatg acggtcaacg atgcggtaga
    28441 atttttccaa cacattccga aaattcaacg caaactccag accatcaagg atgtaggtct
    28501 aggctatgtg accttgggac agccagctac caccctttct gggggagaag cccaacgtat
    28561 gaagttagct agcgaactcc acaaacgctc gacaggaaaa tctttctaca ttctggatga
    28621 gccgacgaca gggcttcata cagaggacat tgctcgcctg ctcaaggttt tagctcgctt
    28681 tgtagacgcc ggcaatacag tcctcgtcat cgagcacaat ctggatgtta tcaagacggc
    28741 agaccatatc attgacttgg gacctgaggg cggtgtcggt ggtggaacca tcatcgtaac
    28801 aggaactcca gaagaagtag ctgccaacga agccagctat acaggacact atttgaaagg
    28861 aaagttacat catgaataaa cgcgtacaag catttctagc taaaatgcaa gaaaaagaac
    28921 tagatggtat catcatcaac aatcttaaaa acgtctatta tttgactggt ttttggggct
    28981 caaacggaac agtctttatc agccgtgacc gtcaggtctt agtgacagac tctcgctata
    29041 tcatcgcagc taagcaagaa accagtggtt ttgagattgt ggctgatcgt gatgaattgg
    29101 ctgtcattgc aggaattgtt aaggacatga acttgactcg tatcggtttt gaagatgaga
    29161 tttcagtgtc ttattaccac cgtatgcagg cagcttttgc aggtttgaac ttgcttccac
    29221 aaactcagtt tgtggaaggt cttcgtatga ttaaggatga ggcagagatt gcagcgattc
    29281 gcaaggcttg ttctatctca gaccaagctt tccgcgatgc gcttgacttt atcaaaccag
    29341 gaaaaactga aattgagatt gccaacttcc ttgatttccg catgcgtgag ttgggagcat
    29401 ctggcttatc ttttgatacg atcctagcta gcggtatcaa ttcttctaaa ccccatgccc
    29461 atccaatgca caaaccagtg gagttgggag aagccattac catggacttc ggctgtctct
    29521 atgaccacta tgtcagtgat atgacccgga ctatctatct agggcatgtt agcgatgagc
    29581 aggcagagat ttacaatacg gttctaaaag ctaaccaagc cttgattgac caagctaagg
    29641 caggcttagg tttccgtgac tttgacaaaa tccctcgtga tattatcatt gaggcaggtt
    29701 atggtgacta ctttactcac ggcattggcc acggtattgg tctggatatc catgaggaac
    29761 cctactttag tcagacttct acagaaacta ttaagacagg tatggccttg accgatgaac
    29821 caggtatcta tatcgaaggc aaatatggcg ttcgtatcga ggatgatatc ctgattacag
    29881 agacaggttg tgaattattg accctagctc caaaagagtt gatagtcatt tagttgtttg
    29941 tcaagaaaaa agtacgaaaa tgacgaaaaa agtcaaaaaa aattaaaaat aggtcgcaag
    30001 tcggatgttt tttatggtat aatagactaa actgatagta acatgtagcg aaaggggtag
    30061 gtacatgatt aaaatttata cagtctcaag ttgtactagt tgtaaaaaag caaaaacctg
    30121 gctcaatgcc caccagttaa gttataaaga acaaaacctt ggtaaagaag gaattacgag
    30181 agaagaatta ctggatattc taaccaaaac agataacgga atagccagca tcgtttcgtc
    30241 taaaaatcgc tatgccaaag cccttggagt ggatattgaa gatttgagtg tcaatgaagt
    30301 tctcaatctg attatggaaa caccgagaat tttaaagagc ccaatccttg tagatgaaaa
    30361 acgcctgcaa gttggctaca aggaagacga tattcgtgcc ttcctaccac gctctgtccg
    30421 taatgtagaa aatgcagaag cacgtttgcg tgcagctcta taaacatcaa ggctgggagc
    30481 acttcccagt cttattctat tttaatttca aaaagaaaga agaaagaaat gaaaaaaata
    30541 gttcttgtta gtctagcttt cctttttgtc ctggttggtt gcggacagaa aaaagaaact
    30601 ggaccagcta caaaaacaga aaaagatacg cttcagtcgg cattgccagt tattgaaaat
    30661 gctgagaaga atacagttgt aactaagact ttggtcttgc ccaagtcaga tgatggtagc
    30721 cagcagacac aaacaattac ttacaaagac aagacttttt tgagtctagc tatccaacaa
    30781 aaacgtccag tctctgatga gttgaagact tatattgacc aacatggagt ggaggaaact
    30841 caaaaagctc ttcttgaagc ggaggagaag gataagtcta tcattgaagc tcgtaaattg
    30901 gcaggtttca aacttgaaac aaaactattg agcgcaacgg aacttcaaac aacgactagt
    30961 tttgattttc aagttctgga tgtcaagaag gcttcccagt tggaacatct gaagaatatt
    31021 ggtttggaaa atcttttgaa aaatgaacca agcaaatata tttcagatag attggcaaat
    31081 ggcgcgacag aacaatagaa aatccaaata aatagactgc ctgaattgta gaaggtaagg
    31141 aattatgcta taatggtact attctaagga aagagggtgt tagaatggga tttactgaag
    31201 aaacagtacg ttttaaattg gacgattcca ataaaaaaga aattagcgaa actttgacag
    31261 atgtttatgc ttcgttgaac gataagggtt acaacccaat taaccaaatc gtaggttacg
    31321 tattgagtgg agaccctgcc tacgttcctc gttataataa tgcacgaaat caaatccgta
    31381 agtatgagcg tgatgaaatc gttgaggaat tggttcgcta ctacctcaaa ggacaaggag
    31441 tcgatctata acctatgaga attatgggat tggacgtcgg ttcaaaaacg gtaggggtgg
    31501 cgattagcga tccgcttggt tttacagctc aagggcttga aatcatccag ataaatgaag
    31561 aacaaggcca atttggtttt gaccgcgtta aggaattggt tgatacttac aaggtggaac
    31621 gatttgtagt gggcttgcct aaaaacatga acaatacaag tggaccgcgc gtagaagcta
    31681 gtcaagccta cggagcaaag ctagaagagt tttttggttt accagtagac tatcaggatg
    31741 aacgcttgac aacagtggct gctgagcgca tgttgattga acaagcagat atcagtcgca
    31801 ataagcgcaa gaaagtcatt gataagttag cagctcagct gattttacaa aattatttag
    31861 atagaaaatt ttaatataaa ggagaggcta tgtcacacga tcataaccac gaccacgaag
    31921 aacgtgaact aatcacacta gtagatgagc aaggaaatga aaccttgttt gaaatccttt
    31981 tgacaattga tggaaaagaa gaatttggta aaaactatgt tcttctagta ccagttaacg
    32041 cagaagaaga cgaagacgga caagttgaaa tccaagctta ctcattcatt gaaaatgaag
    32101 atggaacaga aggcgaattg caaccaatcc cagaagactc agaagacgaa tggaacatga
    32161 ttgaagaagt cttcaacagc tttatggagg agtgatacag tctgggagac tgtatcagcc
    32221 caactccaga aatggggaag agttggaacg tccagtgaac atttttaccc caactcttag
    32281 aaattgagaa gagttggaac atctagtgga tgtttttagc ccatattcac attcatagta
    32341 gctagttatt agctaaccag gtaagaggtc gggacgaaaa tcctggcctt gtttttatta
    32401 gtaaccatac tttaatgcga taattgattg gacttttgtc aaggagatgt gtatgtttga
    32461 agtagaagaa tggctccata gtcggattgg tttgaatttt cgatcaggtt tgggccgaat
    32521 gcagcaagcg gtggatttgt taggaaatcc tgagcagtct taccctatta tccacgtaac
    32581 agggactaat gggaaaggat ctaccattgc ttttatgagg gaattattta tggggcatgg
    32641 caaaaaagtt gcgaccttta cctcccctca tatcgtctct atcaatgacc gaatctgcat
    32701 taatgggcaa cctatagcag acgcagactt tatccgtttg actgatcagg tcaaggagat
    32761 ggagaaaacg cttctgcaaa ctcctgccca gttgtccttt tttgaattgc tgaccttagt
    32821 tgcttttctt tattttaggg agcaagaggt ggatttggtt ttattagaag tgggaattgg
    32881 tggcttactt gacacgacca atgtggtaac tggagagctt gctgtcatca cctccattgg
    32941 gcttgaccat caagaaacct tgggtgatag tctagaagca attgcagagc agaaagctgg
    33001 tattttcaag gctggtaaaa aggcagtgat tgcgaaattg cctccagaag ctagacttgt
    33061 ctgtcagaaa aaagccgaat ctttagctgt tgacctttat caggcaggtc aagatttttc
    33121 agtgctgaat ggtgattttt caagctcttt actaaatctt tcacagctga acataggctt
    33181 agaaggagcc tatcagcagg agaatgcggc cttggcgttg caaacttttc ttctttttat
    33241 gggagaaaga aaggaagcta ttgatgaaca ggctgtaaga aaggccttgg aacagaccca
    33301 ttgggctggt cgcttggagc gtattcgccc acagatttac ttggatggtg ctcataacct
    33361 ccctgccttg actcgcttgg ttgagtttat caaagaaaaa gagcaggaag gctatcgacc
    33421 tcaaatcctc tttggatcct tgaaacgtaa ggattatcaa gggatgttgg gttatctgac
    33481 tgaaaattta cctcaagtgg aactcaaaat gaccggcttt gactatcaag ggtctttgga
    33541 cgagacagat gtaacaggtt accatgtaat tccctcttac cgagaattta tcagcagttt
    33601 cgaagaaagg gcagacgctc aagacttgct gttcgttaca gggtctctct attttatctc
    33661 agaagtacgg ggctacctgc tggaccgtga gcagataaat tgaccccctt ttttgaactt
    33721 gttatactag gggaattgct ggttagagaa aatttctcta aattggtagc agaaaggaaa
    33781 ttcatcatga aattaaaaag attcacactt tctcttgctt ctctagcaag ttttagtctc
    33841 ttagtagctt gttcacaaag agctcaacag gttcaacagc ctgttgctca gcaggtccaa
    33901 cagcctgctc aacagaatac caatactgca aatgcaggag gtaaccaaaa tcaagcggct
    33961 ccagtacaaa accaacctgt tgctcaaccg accgatattg atgggactta tactggtcag
    34021 gatgacggag accgtatcac tttagtggta actggaacga ctggtacatg gactgagctc
    34081 gaatctgacg gggatcagaa agtcaaacag gttacatttg attcagcaaa tcaacgcatg
    34141 attattggcg atgatgtcaa aatttacact gtaaacggta atcaaatcgt cgtagatgat
    34201 atggatagag acccatcgga ccaaatcgtt ttaactaaat aagactatgc aagtagaaag
    34261 ggctggattt ttcagccttt ttacttttac ctagaaaata atcataaata cttgccttct
    34321 accgaatacc tgcgttatac tagtatcaat tacttgtttt tagcattcaa actatcaagg
    34381 aggggatatg aaatatagga aatttcaatt attgatgtcc aagtatggct ttagtctttc
    34441 gattatgcta cttgaacttt gtcttgtttt tggtctcttt ctttatttag gacgcatggc
    34501 tcccatttta tggattactg tcctcattct actgagtatc atcacaatca tttcgatagt
    34561 caaccgtaat acgactcctg agaataaggt aacctggttg ttagtagcct ttgtgccagt
    34621 atttggtccc ttgctctatc tgatgtttgg tgaaaggcga ttgtccaaaa aagaaatcaa
    34681 acaactgaag aagctaggct ctatgcattt ccaagaagca aatagccagc tactaaaaga
    34741 gaaattaaaa gaaagtgaca aggcagctta tggagtcatc aagtccttat tgagtatgga
    34801 taccaatgct gacatctatg atcaaactgc ctctacattt tttcctaacg gagaagctat
    34861 gtggaaaaag atggtagaag atcttaaaaa ggctgagaaa tttattttct tggaatatta
    34921 cattatagaa gaaggtttga tgtggaatcg catactagat atactagagc aaaaggtagc
    34981 tcagggtgta gaggttaaga tgctctatga tgatatcggc tgtatggcta ctttaacagg
    35041 agattatgca catcgacttc gtcagctggg catcgaggcc cataaattca ataaagttat
    35101 tcctcgtttg acagtggctt ataataacag agatcataga aaaatattga ttgttgatgg
    35161 tcagatagcc tatactggtg gggtcaatct ggcagatgag tacattaacc acgtcgagag
    35221 atttggttat tggaaggata gtggaattcg cttagacgga ctagcagtaa aagccctgac
    35281 acgcttattt ttgaccactt ggtacattaa tcgaggagaa attagtgatt ttgatcaata
    35341 tcatttagaa aatcattcta tcccgagtga cggtttaacc attccatacg gaagtggacc
    35401 caagccaatt tttcgagcgc aggtagggaa aaaagtttat cagagtttaa tcaatcaagc
    35461 aacagaatcg gtctatatta cgacacctta tttgattata gattatgatt taacagagac
    35521 aatcaaaaat gcagctatga gaggggtcga tgttcgaatt atcacccctt acataccaga
    35581 taagaagttc attcagttag tcacgagagg agcttatccc gaccttcttt ctgctggtgt
    35641 tcggatttat gagtatagtc caggttttat tcatagtaag cagatgttgg tagacgaaga
    35701 ttttgcggtg gtggggacaa tcaatctcga ctaccggagc ttggtacacc attatgaaaa
    35761 tgcagtctta ctctataaaa ctccttctat aagggaaatc gcccgagatt ttcgaaatat
    35821 atttgcagat tctcaggaag tctatcctca ttctatcaaa acgagctggt atcaaaagct
    35881 tgtaaaagaa atcgcccagc tattcgcccc tatcttataa gaaatctaga acttaggata
    35941 caaaccagac ctatttttct tgtcttttac taatagaaag aaagaggagg ggaattcatg
    36001 ctaactaagg aagaagtgaa tgatatgatt gagttcaaac agacacattt ataccgcttt
    36061 cgggaaattg aaacctttgt gaaactatgc aaaaaatcac tcaaacagcc atcgcaagct
    36121 gacaatccta ggactttttg atatactaag acagataaat tgaacaggag aaacgatatg
    36181 agtgtgtatg gtagagtaga agaagttcat aaggagaatc gtgaacctct agaataccaa
    36241 atcgaacaag aatcgcatca tcgtgaatca agtcgtcttc ctttggtgaa aattttacta
    36301 tggagtacgc ttgtaacggg gataactcta ggagtaccgc tattactcga cttaatgagt
    36361 gcacaagaag tgcaggattt ttatgcaggt tgggggcttc atcagacagg gaagatttac
    36421 agcgactatt atggaagtca aggtttgctt tattatttgc tgacttacgt gagtcagggc
    36481 ggatttttct ttgccatctt tgagtggtta gccttggtag caggaggatt tttccttttt
    36541 agatcagcgg acaccttgac agagcaagga gaccaagctg gacatctggt gactattttt
    36601 tacatgctag ttacaggtct tgcttttggt ggaggctatg cgactctttt agcgcttcct
    36661 ttcttattcg cagcctttag tttagttgcg gcttacctaa gcaatccaag ccatgataag
    36721 ggatttgtac ggattgggct agctttggca ggcggatttt tctttgctcc cttatcatcg
    36781 ctcctgttta ttgctgtagt gagtttaggc ttgttggtct ttaaccttgg gcatagacgc
    36841 tttgcgcatg ggttttatca gtttcttgca gtggctttag gtttttcact tgtcttttat
    36901 ccaactgcct actatagtgc tgcaacagga agttttgggg atgcgattag tggtattcgt
    36961 tatcctattg acagtattcg ctttgatttt acttctaaaa ttttagagaa tatgtttttt
    37021 tatggcttgt tgtcccttgg tttgggattt gtggtttgta tctttttagg tctctttcaa
    37081 tccaaaccct ttaaactata cgtcatttcg gttcctgcaa gtcttgtggt aattttaggt
    37141 ttgattttac ttttcttttc acaagagcct ctgcacgctt cttatttgat ggtcgtcttc
    37201 cctgttttcc tacttttatt ggtaaccaat attaagagtc aacagagggg gcgtagtgct
    37261 agaagaagcc gaagagaaac gccagttagc ctatggagtc gtttcttcaa aggaaatcta
    37321 tatctgctag tttttgggtt tgtctatctt ttgtctgttc cttttttgat gaagtttgtc
    37381 ctttatccag taccttatca agaacgtaat cgtcttgctg atttggtaaa agaggagaca
    37441 aatacggaag atgctatcta tgcatgggat gatactgcga ctctttatcg taagagtgag
    37501 cgcttgtcgc catcggcgat tttgtccccg ttgcactata cagcaactga ggaaaatcgt
    37561 aataagttac ttaatgactt gaaagaaaaa caacctaagg tgattgtggt aaatgacaag
    37621 gtggtagtct ggtctgaagt ggaaacactt ttaaaagaaa attaccaaca agtaaagact
    37681 gattactcag agtttaaagt ctataaaatt aaataaccaa atcaatatct tgtgtatttt
    37741 taaaaatttt aggattttta acacaagata ttgatttttc tttttagagt ggtataatac
    37801 tttttagaaa gaacatttta gaaaagagca tgcgtatgat tgcactagaa gaaaaaatta
    37861 caattttgcc aactctcttc gtcgagaaac gagatgggag acgtgttgta tttgatgtgg
    37921 acaagattga caaggctctc cacaaggcgg ctgacaaggt tatggatgtg acacccctgg
    37981 ttgaaaaacg cctcaatgat ctgactgagc gaattattac agaaattcat agtcgctttc
    38041 cacagggaat taagatttac gaaattcaaa atatcgtaga acatgaactc cttgaagcca
    38101 aagaatatgc gctggctgag gagtatatta cttatcggac acagagggat tttgagcgct
    38161 caaaagcgac ggatatcaac tttagtattc ataaacttct caacaaagac cagacagttg
    38221 tcaatgaaaa tgctaataaa gacagtgatg tctttaacac tcagcgtgat ttgacagcag
    38281 ggattgttgg gaaatcaatc ggactgcaaa tgcttcctaa gcacgtagcc aatgcccacc
    38341 aaaaggggga tatccactat cacgatttgg actacagtcc ctatacccct atgaccaact
    38401 gctgtttgat tgattttaag ggtatgttgg aaaatggttt taagattgga aatgcagagg
    38461 tagagagtcc caagtctatc cagactgcga cagcacagat ttctcaaatc attgccaacg
    38521 ttgcttctag ccagtacggt ggctgttcag ctgaccgtat cgatgaaatt ttggcgcctt
    38581 atgcagagaa gaattatcaa aaacatctca aagatgcaga agagtgggta ttgcctgaaa
    38641 aacgggaaga ttacgcttgg aagaaaacgc aaaaggacat ctacgatgcc atgcaatctc
    38701 ttgagtatga aatcaatact ctcttcactt caaatggaca aacacctttt acttcgttag
    38761 gttttggtct gggaaccagt cgttttgaac gagaaattca aaaagctatt ttaaacattc
    38821 gcatcaaggg tcttggttca gaacaccgta cggctatctt tcctaaactt attttcactc
    38881 tgaaaagagg ccttaattta gaggaaggaa ctcccaacta cgacatcaag cagttggctc
    38941 ttgagtgtgc aaccaaacgg atgtatccag atgttttatc ttacgataag attgttgact
    39001 tgacaggatc cttcaaggtg cctatgggtt gccgttcttt cctccaagga tggaaggatg
    39061 aaaatggtgt agaagtcaat tcaggtcgca tgaatctggg tgttgtgacg gttaatctgc
    39121 ctcgtattgc tcttgagtct gaaggtgata tgaataagtt ctgggaaatc ttcaacgagc
    39181 gaatgaatat cgcagaagat gctcttgttt accgtgtcga acgcactaaa gaggcgacac
    39241 cagcaaatgc tcctattctt tatcagtacg gtgcttttgg ccatcgtcta ggtaaagaag
    39301 aaagtgttga ccagctcttt aagaatcgtc gtgctaccgt ttcgctgggc tatatcggct
    39361 tgtatgaagt agcgacagtt ttctttggta acagctggga aagtaatcca gatgctaagg
    39421 aattcacgct agacatcatt cacgatatga aacgccgtgt agaagagtgg tcagaccaat
    39481 atggctacca tttctctatc tactcaacac catccgaaag tctgacagac cgtttctgtc
    39541 gactagatat agacaagttt ggctctattc ctgatatcac agacaaggaa tactacacca
    39601 actctttcca ctacgatgtt cgtaaaaatc caacaccgtt tgaaaaattg gactttgaga
    39661 aagtctatcc agaagcaggt gcgtcaggtg gtttcatcca ttattgtgag tatccagtcc
    39721 ttcagcaaaa tccaaaggcc ttggaagctg tctgggatta tgcttatgac cgtgtaggct
    39781 atctaggcac caatactccg attgaccgtt gctacaagtg tgactttgaa ggggattttg
    39841 aaccaactga gagagggttt gcttgtccaa actgtggcaa tagcgaccct aaaacagtag
    39901 atgtggtgaa gcgaacttgt ggctacctag gtaatcctca agcaagaccg atggtcaacg
    39961 gccgtcacaa ggaaatcgct gcgcgtgtca aacatatgaa tggttcaacg attaaaatag
    40021 ctgggcatca agtaacaaat tagaaagaaa tgaaatggga aaatatcaac tagacgataa
    40081 ggggcgcgca caagtgaccc gttatcacga gaaacactct aaaggtggag ctggtaagaa
    40141 agaacgcttg cttagcttca gagaacaatt tttaaacaag aacaagaaaa aataaaagtg
    40201 agagccagct ctcgcttttc tcatagtggg aggtaaggat ggaattacgc agaccaagat
    40261 tagcggataa gaaagctgtt ttagatatga tgacagagtt tgaaaaattt cagtcgcctc
    40321 acgacggcgg tttctgggat acagagaact ttgtgtatga agactggtta gaaagcaatc
    40381 aggaacagga aatggggatt aatctgcctg aaggatgggt tcctgcaatt cagttagtgg
    40441 ctttttctga gaaaggtcaa gcagttggat ttcttaatct ccggttgcgc ctcagtaact
    40501 ttctactaga agaaggtggc cacattggct actccattcg tccatctgaa agaggcaagg
    40561 gttatgcaaa agagactctc cgtcagggct tgcaagttgc taaggaaaag aacatcaaga
    40621 aagctctggt gacctgtagc gtgaataatc ctgctagcag agcagtcatt ctagcaaatg
    40681 gtggaatatt tgaggatgct cgcaatggag tcgagcgtta ttggatagag gtagcgaatg
    40741 aataatccaa aaccacaaga atggaaaagc gaggaactta gtcaaggtcg tatcattgac
    40801 tacaaggcct ttaactttgt ggacggcgaa ggcgtgcgta actctctcta tgtatcaggc
    40861 tgtatgtttc actgcgaggg atgttataat gttgcaactt ggtcttttaa tgctggcatt
    40921 ccctatacag cagaattaga agagcagatc atggcagatc ttgctcagcc ctatgttcaa
    40981 ggtttgactt tgttgggagg ggagcctttt cttaatactg ggattctctt gccacttgtt
    41041 aagcggattc ggaaggaatt gccagacaag gacatctggt cctggaccgg ctacacttgg
    41101 gaagaaatga tgttggaaac tccagataaa ctggaattct tgtcactgat tgacattctt
    41161 gtcgatggaa gatatgatcg aactaagaga aatcttatgc tccagtttcg aggttcatct
    41221 aaccaacgaa ttatcgatgt gcaaaaatcg ctcaaaagtg ggcaagtagt gatttgggac
    41281 aagctcaatg acggaaaaga aagctatgaa caggtgaaga gagaatgaag aaaaaatgaa
    41341 gaaaaaagac ttagtagacc aactagtctc agagatcgag acggggaaag tcaggacact
    41401 gggaatatac ggtcatggag cttcaggtaa atcaaccttt gcacaggaat tgtaccaagc
    41461 tttagattct actacagtaa atttgctaga aacagatccc tatatcacct ccggacgcta
    41521 tttggtagta cccaaggacg cgccgaatca aaaggtgaca gccagtctgc cagtggcgca
    41581 tgaactggag agtttgcaga gagatatcct tgccttgcag gcgggtatgg atgtcttgac
    41641 aattgaagaa ccttggaagg ctagtgaggt cttgtctgga gccaaaccaa ttttgattgt
    41701 cgaagggatg tctgttggtt ttctacccaa ggaactcttt gaaaaaacca tctgtttcta
    41761 cacggatgag gagaccgaat taaagcgacg ccttgctaga gatacgactg tgagaaatcg
    41821 ctatgcatcc tttatattgg ctagccatca gatgagacgg gagcagtatc tgcgatacta
    41881 taaagaaact gagtctaagg cggatatctt agtggaccaa tcagaagata aatttgatgt
    41941 caagaggact taacttatgt atagaagaaa tatagaagaa aatccctaat tttagaaaga
    42001 aaaagtagga aaacagtttc atcccaaaaa aacgaaaaaa cctaacaaat cccttgcaat
    42061 cgcaggggat ttgtgttatt ctattatggt gctgtaaatt acagccttag ttttgatgca
    42121 agaggttgcg acacgctcgg ttgcattgcc acgcaacacc gcgtcggttt tcttgtggag
    42181 ctagcctatt atcttaaata gacgaaaagg agaaaaagat ggcaaacaaa aaaatccgta
    42241 tccgtttgaa agcttacgaa caccgtacgc ttgacacagc ggctgcaaaa atcgtagaat
    42301 cagctactcg tacaggtgca caagttgcgg gtccaatccc acttccaact gaacgtagcc
    42361 tctacacaat cattcgtgcg actcacaaat acaaagactc tcgcgaacaa tttgaaatgc
    42421 gtacacacaa acgtttgatc gatatcgtta acccaactca aaaaacagtt gatgccttga
    42481 tgaaattgga tcttccaagt ggtgtaaacg tagaaatcaa actttaatct aaaatataaa
    42541 agagcagagg ctggtgtttc aatctaattg aacacgggct aaactcggtg tgaaaaagat
    42601 aaacttcctc gcgtctgcta gacactgtgt cagtttccta ttttcacttt gagtttgacg
    42661 ccctttgtat cttagacttg agcataaaaa acgctcgtta aaaacttttt gaataaaaaa
    42721 tatagaaaag gaactatttt ctcatgacaa aaggaatctt agggaaaaaa gtgggaatga
    42781 ctcaaatctt cactgaagct ggcgaattga tccctgtaac agttattgaa gcaactccaa
    42841 acgttgttct tcaagttaaa actgttgaaa cagacggata caacgctatc caagttggtt
    42901 tcgatgacaa acgcgaagta ttgagcaaca aacctgctaa aggacatgta gcgaaagcta
    42961 acacggctcc taagcgcttc attcgtgaat tcaaaaacgt tgaaggcttg gaagttggtg
    43021 ctgaaattac agttgaaaca ttcgcagctg gagacgttgt tgacgtaact ggtacttcta
    43081 aaggtaaagg tttccaaggt gttatcaaac gccacggaca atcacgtgga ccaatggctc
    43141 acggttctcg ttaccaccgt cgtccaggtt ctatgggacc tgttgcacct aaccgcgtat
    43201 tcaaaggtaa aaaccttgca gggcgtatgg gtggcgaccg cgtaacaatt caaaaccttg
    43261 aagttgtaca agttgttcca gaaaagaacg ttatccttat caaaggtaac gtaccaggtg
    43321 ctaagaaatc tcttatcact atcaaatcag cagttaaagc tggtaaataa taaagaaagg
    43381 ggaaatcagt cacaatggca aacgtaacat tatttgacca aactggtaaa gaagctggcc
    43441 aagttgttct tagcgatgca gtatttggta tcgaaccaaa tgaatcagtt gtgtttgatg
    43501 taatcatcag ccaacgcgca agccttcgtc aaggaacaca cgctgttaaa aaccgctctg
    43561 cagtatcagg tggtggacgc aaaccatggc gtcaaaaagg aactggacgt gctcgtcaag
    43621 gttctatccg ctcaccacaa tggcgtggtg gtggtgttgt cttcggacca actccacgtt
    43681 catacggcta caaacttcca caaaaagttc gtcgcctagc tcttaaatca gtttactctg
    43741 aaaaagttgc tgaaaacaaa ttcgtagctg tagacgctct ttcatttaca gctccaaaaa
    43801 ctgctgaatt tgcaaaagtt cttgcagcat tgagcatcga ttctaaagtt cttgttatcc
    43861 ttgaagaagg aaatgaattc gcagctcttt cagctcgtaa ccttccaaac gtgaaagttg
    43921 caactgctac aactgcaagt gttcttgaca tcgcaaatag cgacaaactt cttgtcacac
    43981 aagcagctat ctctaaaatc gaggaggttc ttgcataatg aatttgtatg atgttatcaa
    44041 aaaacctgtc atcactgaaa gctcaatggc tcaacttgaa gcagggaaat atgtatttga
    44101 agttgacact cgtgcacaca aacttttgat caagcaagct gttgaagctg ctttcgaagg
    44161 tgttaaagtt gccaatgtta acacaatcaa cgtaaaacca aaagctaaac gtgttggacg
    44221 ttacactggt tttactaaca aaactaaaaa agctatcatc acacttacag ctgattctaa
    44281 agcaatcgag ttgtttgctg ctgaagctga ataatctaag gaggaaatat cgtgggaatt
    44341 cgtgtttata aaccaacaac aaacggtcgc cgtaatatga cttctttgga tttcgctgaa
    44401 atcacaacaa gcactcctga aaaatcattg cttgttgcat tgaagagcaa ggctggtcgt
    44461 aacaacaacg gtcgtatcac agttcgtcac caaggtggtg gacacaaacg tttttaccgt
    44521 ttggttgact tcaaacgtaa taaagacaac gttgaagcag ttgttaaaac aatcgagtac
    44581 gatccaaacc gttctgcaaa catcgctctt gtacactaca ctgacggtgt gaaagcatac
    44641 atcatcgctc caaaaggtct tgaagtaggt caacgtatcg tttcaggtcc agaagcagat
    44701 atcaaagtcg gaaacgctct tccacttgct aacatcccag ttggtacttt gattcacaac
    44761 atcgagttga aaccaggtcg tggtggtgaa ttggtacgtg ctgctggtgc atctgctcaa
    44821 gtattgggtt ctgaaggtaa atatgttctt gttcgtcttc aatcaggtga agttcgtatg
    44881 attcttggaa cttgccgtgc tacagttggt gttgtcggaa acgaacaaca tggacttgta
    44941 aaccttggta aagcaggacg tagccgttgg aaaggtatcc gcccaacagt tcgtggttct
    45001 gtaatgaacc ctaacgatca cccacacggt ggtggtgaag gtaaagcacc agttggtcgt
    45061 aaagcaccat ctactccatg gggcaaacct gctcttggtc ttaaaactcg taacaagaaa
    45121 gcgaaatctg acaaacttat cgttcgtcgt cgcaacgaga aataatatta aactagtcgc
    45181 ttaagcaact agtaaatccg ccagctcggt agcgctccat aggagtgcaa gccgctgtgg
    45241 tacaacattt aaaggagaaa atataaaaat gggacgcagt cttaaaaaag gacctttcgt
    45301 cgatgagcat ttgatgaaaa aagttgaagc tcaagctaac gacgaaaaga aaaaagttat
    45361 taaaacttgg tcacgtcgtt caacgatctt cccaagtttc attggttaca ctattgcagt
    45421 ttatgacgga cgtaaacacg tacctgttta catccaagaa gacatggtag gccacaaact
    45481 tggtgaattt gcaccaactc gtacttacaa aggtcacgct gcagacgaca agaaaacacg
    45541 tagaaaataa ggagaacata aatggcagaa attacttcag ctaaagcaat ggctcgtaca
    45601 gtacgtgttt cacctcgtaa atcacgtctt gttcttgata acatccgtgg taaaagcgta
    45661 gccgatgcaa tcgcaatctt gacattcact ccaaacaaag ctgctgaaat catcttgaaa
    45721 gttttgaact cagctgtagc taacgctgaa aacaactttg gtttggataa agctaatttg
    45781 gtagtatctg aagcattcgc aaacgaagga ccaactatga aacgtttccg tccacgtgcg
    45841 aaaggttcag cttcaccaat caacaaacgt acagctcaca tcactgtagc tgttgcagaa
    45901 aaataaggag gtaaaatcgt gggtcaaaaa gtacatccaa ttggtatgcg tgtcggcatc
    45961 atccgtgatt gggatgccaa atggtatgct gaaaaagaat acgcggatta ccttcatgaa
    46021 gatcttgcaa tccgtaaatt cgttcaaaaa gaacttgctg acgcagcagt ttcaactatt
    46081 gaaatcgaac gcgcagtaaa caaagttaac gtttcacttc acactgctaa accaggtatg
    46141 gttatcggta aaggtggtgc taacgttgat gcactccgtg caaaacttaa caaattgact
    46201 ggaaaacaag tacacatcaa catcatcgaa atcaaacaac ctgatttgga tgctcacctt
    46261 gtaggtgaag gaattgctcg tcaattggag caacgtgttg ctttccgtcg tgcacaaaaa
    46321 caagcaatcc aacgtgcaat gcgtgctgga gctaaaggaa tcaaaactca agtatcaggt
    46381 cgtttgaacg gtgcagatat cgcccgtgct gaaggatact ctgaaggaac tgttccgctt
    46441 cacacacttc gtgcagatat cgattacgct tgggaagaag cagatactac atacggtaaa
    46501 cttggtgtta aagtatggat ctaccgtggt gaagttcttc cagctcgtaa aaacactaaa
    46561 ggaggtaaat aaccaatgtt agtacctaaa cgtgttaaac accgtcgtga gttccgtgga
    46621 aaaatgcgcg gtgaagcaaa aggtggaaaa gaagtagcat tcggtgaata cggtcttcaa
    46681 gctacaacta gccactggat cactaaccgc caaatcgaag ctgctcgtat cgccatgact
    46741 cgttacatga aacgtggtgg taaagtttgg attaaaatct tcccacacaa atcatacact
    46801 gctaaagcta tcggtgtgcg tatgggatct ggtaaagggg cacctgaagg ttgggtagca
    46861 ccagttaaac gtggtaaagt gatgttcgaa atcgctggtg tatctgaaga gattgcacgt
    46921 gaagcgcttc gacttgctag ccacaaattg ccagttaaat gtaaattcgt aaaacgtgaa
    46981 gcagaataag gagaaggcat gaaacttaat gaagtaaaag aatttgttaa agaacttcgt
    47041 ggtctttctc aagaagaact cgcgaagcgc gaaaacgaat tgaaaaaaga attgtttgaa
    47101 cttcgtttcc aagctgctac tggtcaattg gaacaaacag ctcgcttgaa agaagttaaa
    47161 aaacaaatcg ctcgtatcaa aacagttcaa tctgaagcga aataatagac tagggaagga
    47221 gaaatttcaa tggaacgcaa taatcgtaaa gttcttgttg gacgtgttgt atctgacaaa
    47281 atggacaaga caatcacagt tgtagttgaa acaaaacgta accacccagt ctatggtaaa
    47341 cgtattaact actctaaaaa atacaaagct catgatgaaa acaatgttgc caaagaaggc
    47401 gatatcgtac gtatcatgga aactcgcccg ctttcagcta caaaacgttt ccgtcttgta
    47461 gaagttgttg aagaagcggt catcatctaa tcaaacctga aaggagaaaa ctgaaatgat
    47521 tcaaacagaa actcgtttga aagtcgcaga caacagcggt gctcgcgaaa tcttgactat
    47581 caaagttctt ggtggttcag gacgtaaatt tgcaaacatc ggtgatgtta tcgtggcatc
    47641 tgtaaaacaa gctactcctg gtggtgcggt taaaaaaggt gacgttgtta aagcagttat
    47701 cgttcgtact aaatcaggtg ctcgtcgtgc tgatggttca tacatcaaat ttgacgaaaa
    47761 cgcagcagtt atcatccgtg aagacaaaac tcctcgcgga acacgtatct ttggcccagt
    47821 tgcacgtgaa ttgcgtgaag gtggcttcat gaagatcgtg tcacttgctc cagaagtact
    47881 ttaattttta ggaacaaact agtcccctag cttcaagcta gggtgccctt atgggcgtaa
    47941 gaaaaatcaa ggagaaacct aatgtttgta aaaaaaggcg acaaagttcg cgtaatcgct
    48001 ggtaaagata agggaacaga agctgttgtc cttactgccc ttccaaaagt aaacaaagtt
    48061 atcgttgaag gtgttaacat tgttaagaaa caccaacgtc caactaacga gcttcctcaa
    48121 ggtggtatca tcgagaaaga agcagctatc cacgtatcaa acgttcaagt tttggacaaa
    48181 aatggtgtag ctggtcgtgt tggttacaaa tttgtagacg gtaaaaaagt tcgctacaac
    48241 aaaaaatcag gcgaagtgct tgattaatca cgaaggaaag gagaagtata atggcaaatc
    48301 gtttaaaaga aaaatatctt aatgaagtag ttcctgcttt gacagaacaa ttcaactact
    48361 catcagtgat ggctgtgcct aaagtagata agattgtttt gaacatgggt gttggtgaag
    48421 ctgtatcaaa cgctaaaagc cttgaaaaag ctgctgaaga attggcactt atctcaggtc
    48481 aaaaaccact tatcactaaa gctaaaaaat caatcgccgg cttccgtctt cgtgaaggtg
    48541 ttgcgatcgg tgcaaaagtt acccttcgtg gtgaacgtat gtacgaattc ttggataaat
    48601 tggtatcagt ttcacttcca cgtgtacgtg acttccacgg tgttccaaca aaatcatttg
    48661 atggacgcgg gaactacaca cttggtgtga aagaacaatt aatcttccca gaaatcaact
    48721 tcgatgacgt tgacaaaact cgtggtcttg acatcgttat cgtaacaact gctaacactg
    48781 acgaagagtc acgtgcattg cttacaggcc ttggaatgcc ttttgcaaaa taatatagga
    48841 ggtaaatcta atggctaaaa aatcaatggt agctagagag gctaaacgcc aaaaaattgt
    48901 tgaccgttat gctgaaaaac gtgctgcatt aaaggcggca ggggactacg aaggtttatc
    48961 taaattacct cgcaacgctt caccgactcg tttacataat cgttgtagag ttacggggcg
    49021 cccacattca gtttaccgca aatttggtct gagtcgtatc gcttttcgcg aacttgcgca
    49081 taaaggtcaa attcctggtg taacaaaagc atcttggtaa tttaagatat caagggcgtc
    49141 aaaactccaa gtaaaaatag gaaacttgac gaagaaacta aagtttctag gaaagtttat
    49201 ctttttcaca cagagtttag cccgggttca attgggcttg ccaatttgaa cacgagctac
    49261 agctttggca aaaaagacca atttgctttg gagcattgct tctgcattaa attgtctatt
    49321 tttgctcgtg ctgttacgct ctttgtatca tgtattaact agcaagtgca acttgcaaac
    49381 tactagtaag aggagaaaaa caaaatggtt atgactgacc caatcgcaga cttcctaact
    49441 cgtattcgta atgctaacca agctaaacac gaagtacttg aagtacctgc atcaaacatc
    49501 aaaaaaggga ttgctgaaat ccttaaacgc gaaggttttg taaaaaacgt tgaaatcatc
    49561 gaagatgaca aacaaggcgt catccgtgta tttcttaaat acggaccaaa tggtgaaaaa
    49621 gttatcacta acttgaaacg tgtttctaaa ccaggacttc gtgtctacaa aaaacgtgaa
    49681 gaccttccaa aagttcttaa cggacttgga attgccatcc tttcaacttc tgaaggtttg
    49741 cttactgata aagaagcacg ccaaaagaat gttggtggtg aggttatcgc ttacgtttgg
    49801 taaaatcaag atacaaagct cgtaaagaac aaagcaaaat taggaagttg gagaagtttg
    49861 tttacaaaca agccaactta tctattttgc acagttctta gagcgtgttc agttcagctc
    49921 ttgaactaaa taagtatctg aaccccgtga aaactggccg ttttggcctg acaatttaac
    49981 aggagaaaat aaacatgtca cgtattggta ataaagttat cgtgttgcct gctggtgttg
    50041 aactcgctaa caatgacaac gttgtaactg taaaaggacc taaaggagaa cttactcgtg
    50101 agttctcaaa agatattgaa atccgtgtgg aaggtactga agtaactctt caccgtccaa
    50161 acgattcaaa agaaatgaaa actatccacg gaactactcg tgcccttttg aacaacatgg
    50221 ttgttggtgt atcagaagga ttcaagaaag aacttgaaat gcgtggggtt ggttaccgtg
    50281 cacagcttca aggatctaaa cttgttttgg ctgttggtaa atctcatcca gacgaagttg
    50341 aagctccaga aggaattact tttgaacttc caaacccaac aacaatcgtt gttagcggaa
    50401 tttcaaaaga agtagttggt caaacagctg cttacgtacg tagccttcgt tcaccagaac
    50461 catataaagg taaaggtatc cgttacgttg gtgaattcgt tcgccgtaaa gaaggtaaaa
    50521 caggtaaata atgttgagtg gttgatcatc aaccaccaac ctattttcca actttgtgca
    50581 tagcacacga tttaaaacta aagaggtgaa aactgtgatt tcaaaaccag ataaaaacaa
    50641 actccgccaa aaacgccacc gtcgcgttcg cggaaaactc tctggaactg ctgatcgccc
    50701 acgtttgaac gtattccgtt ctaatacagg catctacgct caagtgattg atgacgtagc
    50761 gggtgtaacg ctcgcaagtg cttcaactct tgataaagaa gtttcaaaag gaactaaaac
    50821 tgaacaagcc gttgctgtcg gtaaactcgt tgcagaacgt gcaaacgcta aaggtatttc
    50881 agaagtggtg ttcgaccgcg gtggatatct atatcacgga cgtgtgaaag ctttggctga
    50941 tgcagctcgt gaaaacggat tgaaattcta ataggaggac actagaaaat ggcatttaaa
    51001 gacaatgcag ttgaattaga agaacgcgta gttgctgtca accgtgttac aaaagttgtt
    51061 aaaggtggac gtcgtcttcg tttcgcagct cttgttgttg ttggtgacca caatggtcgc
    51121 gtaggatttg gtactggtaa agctcaagaa gttccagaag caatccgtaa agcagtagat
    51181 gatgctaaga aaaacttgat cgaagttcct atggttggaa caacaatccc acacgaagtt
    51241 ctttcagaat tcggtggagc taaagtattg ttgaaacctg ctgtagaagg ttctggagtt
    51301 gccgctggtg gtgcagttcg tgccgttgtg gaattggcag gtgtggcaga tattacatct
    51361 aaatcacttg gttctaacac tccaatcaac attgttcgtg caactgttga aggtttgaaa
    51421 caattgaaac gcgctgaaga aattgctgcc cttcgtggta tttcagtttc tgatttggca
    51481 taagaaaggg gataaaatgg ctcaaattaa aattactttg actaagtctc caatcggacg
    51541 cattccatca caacgtaaaa ctgttgtagc acttggactt ggcaaattga acagctctgt
    51601 tattaaagaa gataacgctg ctatccgtgg tatgattaca gcagtatctc acttagtaac
    51661 agttgaagaa gtaaactaat gaagttttag gggatgtgca ctgtaccatc ccctaaaact
    51721 agatatagtc atctatgatg acatcgtata ggcgagttga tgggggagac aaccttttct
    51781 cccttatcgg cgctagcatt ttacaaaaga ggagaaaata aaaatgaaac ttcatgaatt
    51841 gaaacctgca gaaggttctc gtaaagtacg taaccgcgtt ggtcgtggta cttcatcagg
    51901 taacggtaaa acatctggtc gtggtcaaaa aggtcaaaaa gctcgtagcg gtggcggagt
    51961 tcgccttggt tttgaaggtg gacaaactcc attgttccgt cgtcttccaa aacgtggatt
    52021 cactaacatc aacgctaaag aatacgcaat tgtgaacctt gaccaattga acgtctttga
    52081 agatggtgct gaagtaactc cagttgttct tatcgaagca ggaattgtta aagctgaaaa
    52141 gtcaggtatt aaaattcttg gtaacggtga gttgactaag aaattgactg tgaaagcagc
    52201 taaattctct aaatcagctg aagaagctat cactgctaaa ggtggttcag tagaagtcat
    52261 ctaagagagg tgacctatgt tttttaaatt attaagagaa gctcttaaag tcaagcaggt
    52321 tcgatcaaaa attttattta caatttttat cgttttggtc tttcgtatcg gaactagcat
    52381 tacagttcct ggtgtgaatg ccaatagctt gaatgcttta agtggattat ccttcttaaa
    52441 catgttgagc ttggtgtcgg ggaatgccct aaaaaacttt tcgatttttg ccctaggagt
    52501 tagtccctat atcaccgctt ctattgttgt ccaactcttg caaatggata ttttacccaa
    52561 gtttgtagag tggggtaaac aaggggaagt aggtcgaaga aaattgaatc aagctactcg
    52621 ttatattgct ctagttctcg cttttgtgca atctatcggg attacagctg gttttaatac
    52681 cttggctgga gctcaattga ttaaaactgc tttaactcca caagtttttc tgacgattgg
    52741 tatcatctta acagctggta gtatgattgt cacttggttg ggtgagcaaa ttacagataa
    52801 gggatacgga aacggtgttt ccatgattat ctttgccggg attgtttcct caattccaga
    52861 gatgattcag ggcatctatg tggactactt tgtgaacgtc ccaagtagcc gtatcacttc
    52921 atctatcatt ttcgtaatca ttttgattat tactgtattg ttgattattt actttacaac
    52981 ttatgttcaa caagcagaat acaaaattcc aatccaatat actaaggttg cacaaggtgc
    53041 tccatctagc tcttaccttc cgttaaaggt aaaccctgct ggagttatcc ctgttatctt
    53101 tgccagttcg attactgcag cgcctgcggc tattcttcag tttttgagtg ccacaggtca
    53161 tgattgggct tgggtaaggg tagcacaaga gatgttggca actacttctc caactggtat
    53221 tgccatgtat gctttgttga ttattctctt tacattcttc tatacgtttg tacagattaa
    53281 tcctgaaaaa gcagcagaga gcctacaaaa gagtggtgcc tatatccatg gagttcgtcc
    53341 tggtaaaggt acagaagaat atatgtctaa acttcttcgt cgtcttgcaa ctgttggttc
    53401 cctcttcctt ggtgtgattt ccattttacc gattgcagct aaagatgtat ttggtctttc
    53461 tgatgttgtt gcctttggtg gaacaagtct cttgatcatt atctctacag gtatcgaagg
    53521 aatcaagcaa ttggaaggtt acctattgaa acgtaagtat gttggtttca tggacagaac
    53581 agaataaaag tatttactga atcagtaaat actgagggag tggaggttta aactctgaca
    53641 tttgtaagag ttggatctcc cctcttctat tttgttttta aataggggtg aaaagacttt
    53701 ttgcttctat ttaaaaataa aataaggaga tcaaatcatg aatcttttga ttatgggctt
    53761 acctggtgca ggtaagggaa ctcaagcagc aaaaatcgta gaacaattcc atgttgcaca
    53821 tatctcaaca ggtgatatgt tccgcgctgc aatggcaaat caaactgaaa tgggtgttct
    53881 tgctaagtca tatattgaca agggtgaatt ggttcctgac gaagttacaa atggaatcgt
    53941 aaaagaacgc ctttcacaag atgatattaa agaaacagga ttcttattgg atggttaccc
    54001 acgtacaatt gaacaagctc atgccttgga caaaacattg gctgaacttg gcattgaact
    54061 agaaggtatt atcaatattg aagtgaaccc tgacagcctc ttggaacgtt tgagtggccg
    54121 tatcatccac cgcgtaactg gagaaacttt ccacaaggtc tttaacccac cagttgacta
    54181 taaagaagaa gattactacc aacgtgaaga tgataagcct gagacagtaa aacgtcgttt
    54241 ggatgttaat attgctcaag gagaaccaat cattgctcac taccgtgcca aaggtttggt
    54301 tcatgacatc gaaggtaatc aagatatcaa tgatgtcttc tcagatattg aaaaagtatt
    54361 gacaaatttg aaataaagcg tttttcgcac ttgcaaaaat ccgctacaaa tgttatactg
    54421 agatagtctg acttataatt gttgtctctg tgtctagagg catcgaatcg aaatttatgg
    54481 aggtgctttt gcgtggcaaa agacgatgtg attgaagttg aaggcaaagt agttgataca
    54541 atgccgaatg caatgtttac ggttgaactt gaaaatggac atcagatttt agcaacagtt
    54601 tctggtaaaa ttcgtaaaaa ctatattcgt attttagcgg gagatcgtgt tactgtcgaa
    54661 atgagtccat atgacttgac acgtggacgt atcacttacc gctttaaata atcgaaaaac
    54721 ttggagggat aagaaatgaa agtaagacca tcggtcaaac caatttgcga atactgtaaa
    54781 gttattcgtc gtaatggtcg tgttatggta atttgcccag caaatccaaa acacaaacaa
    54841 cgtcaaggat aagatagaaa ggagaaaaca tggctcgtat tgctggagtt gatattccaa
    54901 atgacaaacg cgtagtaatc tcattgactt atgtttatgg tatcggactt gcaacatcta
    54961 agaaaatttt ggctgctgct ggaatctcag aagatgttcg tgtacgtgat cttacatcag
    55021 atcaagaaga tgctatccgt cgtgaagtgg atgcaatcaa agttgaaggt gaccttcgtc
    55081 gtgaagtaaa cttgaacatc aaacgtttga tggaaatcgg ttcataccgt ggtatccgtc
    55141 accgtcgtgg acttcctgtc cgtggacaaa acactaaaaa caacgctcgc actcgtaaag
    55201 gtaaagctgt tgcgattgct ggtaagaaaa aataatatag gaggtaaaag tcttggctaa
    55261 accaacacgt aaacgtcgtg tgaaaaagaa tatcgaatct ggtattgctc atattcacgc
    55321 tacatttaat aacactattg ttatgattac tgatgtgcat ggtaatgcaa ttgcttggtc
    55381 atcagctggt gctcttggtt tcaaaggttc tcgtaaatct acaccattcg ctgctcaaat
    55441 ggcttctgaa gctgctgcta aatctgcaca agaacacggt cttaaatcag ttgaagttac
    55501 tgtaaaaggt ccaggttctg gtcgtgagtc agctattcgt gcgcttgctg ccgctggtct
    55561 tgaagtaaca gcaattcgtg atgtgactcc agtgccacac aatggtgctc gtcctccaaa
    55621 acgtcgccgt gtataatcat cgcattacac tgcttttcgt ttaagaggga gtaactaaat
    55681 gatcgagttt gaaaaaccaa atataacaaa aattgatgaa aataaagatt atggcaagtt
    55741 tgtaatcgaa ccacttgaac gtggctacgg tacaactctt ggtaactctc ttcgtcgtgt
    55801 acttctagct tctctaccag gagcagctgt gacatctatc aacattgatg gtgtgttaca
    55861 tgagtttgac acagttccag gtgttcgtga agacgtgatg caaatcattc tgaacattaa
    55921 aggaattgca gtgaaatcgt acgttgaaga cgaaaaaatc atcgaactgg atgttgaagg
    55981 tcctgctgaa gtaacagctg gtgacatttt gacagatagc gatattgaaa ttgtaaatcc
    56041 agatcattat ctctttacaa tcggtgaagg ttcttctcta aaagcgacta tgactgttaa
    56101 cagtggtcgt ggatatgtac ctgctgatga aaataaaaag gataatgcac cagttggaac
    56161 acttgctgta gattctattt atacaccagt tacaaaagtc aactatcaag tggaacctgc
    56221 tcgtgtaggt agcaatgatg gtttcgacaa attaaccctt gaaatcttga caaatggaac
    56281 aattattcca gaagatgctt tagggctttc agcacgtatt ttgacagaac atcttgattt
    56341 gtttacaaat cttactgaga ttgctaagtc aactgaagtg atgaaagaag ctgatactga
    56401 atctgacgac cgtattttag atcgtacgat tgaggaactg gacttgtctg tgcgttcata
    56461 caactgttta aaacgtgccg gtatcaatac tgtgcatgat ttgacagaaa aatctgaagc
    56521 agagatgatg aaagtacgaa atcttggacg caagagtttg gaagaagtga aactcaaact
    56581 cattgatttg ggtcttggat taaaagataa ataaaggagg aatacatggc ttaccgtaaa
    56641 ctaggacgca ctagctcaca acgtaaagca atgcttcgcg atttgacaac tgaccttttg
    56701 atcaacgaat caatcgtgac aactgaagct cgtgctaaag aaatccgtaa aactgttgaa
    56761 aaaatgatta ctctaggtaa acgtggtgat ttgcatgcac gtcgtcaagc agctgctttc
    56821 gtacgtaatg aaatcgcatc tgaaaactat gatgaagcaa ctgataagta cacttctact
    56881 acagcacttc aaaaattgtt ctcagaaatc gcacctcgtt atgctgaacg taacggtgga
    56941 tacactcgta tccttaaaac tgaaccacgt cgtggtgatg cagcgccaat ggcgatcatc
    57001 gaattagtat aaaatcatca attttgttga gtgttatgat gatggagtct tgtgctctta
    57061 gtctagctct ggtctaccgc taggatttcg gtcctagcgg gaacactcat cataagttgg
    57121 gatagtagac gcttgtttac gaaattgttt ttttcttaag aacaacttcg taagcaggcg
    57181 tttttgagta ttttcgttag aattatgcta tactatttga aaagaatcct gtttaatgtt
    57241 aaggtttctt attttaagaa gaattggagt ttacttatga aagccattat aactgttgtt
    57301 ggtaaagata aatctggaat tgttgcaggt gtttctggta aaattgcaga attaggattg
    57361 aatattgacg atatctctca aactgtcttg gatgaatatt ttacgatgat ggctgttgta
    57421 tctagtgatg aaaagcaaga ttttacctat cttcgtaatg aatttgaagc ttttgggcaa
    57481 actttgaatg taaaaatcaa tattcagagt gcagcgattt tcgaagctat gtataatatc
    57541 taggaggtta tcatggatat tagacaagtt actgaaacca tcgccatgat tgaggagcaa
    57601 aatttcgata tcagaaccat taccatgggg atttctcttt tggattgtat cgatccagat
    57661 atcaatcgtg ctgcggagaa aatctatcaa aaaattacga caaaggcggc taatttagta
    57721 gctgttggtg atgaaattgc ggctgagttg ggaattccta tcgttaataa gcgtgtatcg
    57781 gtgacaccta tttctctgat tggggcagcg acagatgaga cggactacgt ggttctggca
    57841 aaagcgcttg ataaggctgc gaaagagatt ggtgtggact ttattggtgg tttttctgcc
    57901 ttagtacaaa aaggttatca aaagggagat gagattctca tcaattccat tcctcgcgct
    57961 ttgactgaga cggataaggt ctgctcgtca gtcaatatcg gctcaaccaa gtctggtatt
    58021 aatatgacgg ctgtggcaga tatgggacga attatcaagg aaacggcaaa tctttcagat
    58081 atgggagcgg ccaagttggt tgtattcgct aatgctgttg aggacaatcc atttatggcg
    58141 ggtgcctttc atggtgttgg ggaagcagat gttatcatca atgtcggagt ttctggtcct
    58201 ggtgtggtga aacgtgcttt ggaaaaagtt cgtggacaga gctttgatgt agtagccgaa
    58261 acagttaaga aaactgcctt taaaatcact cgtatcggtc aattggttgg tcaaatggcc
    58321 agtgagagac tgggtgtgga gtttggtatt gtggacttga gtttggcacc aacccctgcg
    58381 gttggagact ctgtggcacg tgtccttgag gaaatggggc tagaaacagt tggcacgcat
    58441 ggaacgacag ctgccttggc cctcttgaac gaccaagtta aaaagggtgg agtgatggcc
    58501 tgtaatcagg tcggtggtct atctggtgcc tttatccctg tttctgagga tgaaggaatg
    58561 attgctgcag tgcaaaatgg ctctcttaat ttagaaaaac tagaagctat gacggctatc
    58621 tgttctgttg gattggatat gattgccatc ccagaagata cgcctgctga aactattgcg
    58681 gctatgattg cggatgaagc agcaatcggt gttatcaaca tgaaaacaac agctgttcgt
    58741 atcattccca aaggaagaga aggcgatatg attgagtttg gtggtctatt aggaactgca
    58801 cccgttatga aggttaatgg ggcttcgtct gtcgacttca tctctcgcgg tggacaaatc
    58861 ccagcaccaa ttcatagttt taaaaattaa gaaaatagga gaaattttaa gttctattta
    58921 agattagatg tgtatactat aatcattaaa taaagacctc ctaatattat ttgaaacaga
    58981 taacactgaa ttagtttgaa tttgattttc atctaatatc tttatttaat gaactcctaa
    59041 actttttcat aataatctcc ttcaaaagtc gcctgtatgg gtggctttta ttttatcatt
    59101 catgatataa tagaagcaaa cggaggacgg aaaatggtaa aagtacgatt gtatttgata
    59161 cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc aaggttggag cgatactccc
    59221 ttaactgctg aaggtgaacg agggattcaa gagttaggaa ttggtttgcg agaatctgat
    59281 ctacagtttg agcgcgctta ttcgagtgat tctggtcgta ccattcagac catgggaatt
    59341 atccttgaag aacttggctt gcaggggaaa atcccttatc gcatggacaa gcgtatcaga
    59401 gaatggtgtt tcggtagttt tgatggagcc tatgatggcg atcttttcat gggcattatt
    59461 cctcgtatct ttaatgtgga ccacgttcac caattgtctt atgctgaact ggctgagggc
    59521 ttggtagagg tcgatacagc tggttgggct gaaggctggg aaaaactcag tggccgaatc
    59581 aaggaaggct ttgaaatgat tgcaaaagaa atggaagatc aaggtggagg taacgccctt
    59641 gttgtcagcc atggaatgac tattggaacc attgtttatc tgattaatgg catgcatccg
    59701 catggtctag ataatggtag cgtgacgatt cttgaatatg aggacggtca gtttagggtt
    59761 gaagttgtcg gtgaccgtag ttaccgagag ctaggacgtg agaagatgga agaaggctct
    59821 atttaatcag tctagacttg cttgccatga gctagggatt tgataagaat atcaagataa
    59881 gaaaaaacag ccgagggtac tcctttcggc tgtttttgat gtggaaaact aaagtgtaat
    59941 gctattgctt ttagagattt tcataaacaa gagcaaggaa cctactgtta gaacagtcag
    60001 gatagttgac aaggctgcgg ctacaccgta atttcctctg agaacctctg tataaatagc
    60061 tacagtcatt gttcttgttt tgacattgta gaggaggata gaagtagaga gttctgaaat
    60121 cagtgtgacc caagatagga tggctccaga aataatatcc gatagcatca ttggagttgt
    60181 aatcttagca aagatattga gacgactact tcctaagctt tcagcagctt cttcaatact
    60241 tggtgctatt tgttgtaagc tagcaacaga tgagcgaata gtataaggta attttctggc
    60301 agatagagac ataatcaaga tgaaagcagt ccctgtaatc ataagaaatc cacttccaaa
    60361 tagaccagag aaatgaaggc aatccctaga acggttcctg gtacaatata aggtaccata
    60421 ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc taacggctag gtaggagata
    60481 aatgtcgcaa atagaacaac tagaactaag gcaatcaaag ggatacgaat ggtattgaaa
    60541 atagcagatc ccatacgatg gaaagctacc ttgtaactgt ttggagaata acctttaaca
    60601 gataccatac ctgatgtttt taggaaagag gtataaatta agtagatttg aggtaaaaca
    60661 gagataaaga taattccgta gactgttgca taaatggcag ctatttttcc ttttgtagtt
    60721 tttttaggct caattggatg gagcagattc atgctgaaac tgtagcggtt tgcaatgtgt
    60781 ttttggataa ggaaaattgc caaggcaatg ataatcgcca taattgcaaa agcagaattt
    60841 cctccaacct cgctaataaa ttgggtataa atcaggacag ggaaagtccg atatccttcg
    60901 ccaatcaaca taggcgttcc aaagtctgag aatgctctca taaatacaag caaggagctg
    60961 ctagtaaggt tggaactagg agaggtaaaa caaccgttac gatacgctta aatccgaagg
    61021 acccccatgc tttcagctgc ttcaagtaga gaattgtcaa tactgttcat tgttccagca
    61081 acatatagaa ataccagtgg gaatagttgc agtgtaaaga caagtacaat tcctttgaat
    61141 ccataaatat cgatagctgg aagatgaagg gcatttgtca aaaatttagt gatgacccca
    61201 tttcgtccta gcaagagaac ccaggagtag gctcctacga aaggagctga catggaagca
    61261 atgataatca atatttgtag aaatttctcc cccttgaagt catacataga gaagagataa
    61321 gctaataggg ttcctacaac taaggaagtg acagtagcgg taatggaaac cttgaaactg
    61381 ttgactagtg tctcagagta gtagacttta ctaaagaaag tgacaaaatt agctagtgag
    61441 aattatcctt catgtataag tgcttacttg agcacggtaa tgataggata aacgagaaag
    61501 acaagatagg taagaaagag gaggctgtcc aaatatttag ttttttacat tccatggttg
    61561 actcctttta tcaggttttg ggaaccatct gcagaaaaga tgtttaattt ttgcgtattg
    61621 attcgtagac gaatacgatt gtctttttgt agatcttctt caaaagttga ttcttcacta
    61681 acttgaattt ttgaggcaaa acctgtctca atgaaatact ccgtatttag tccaagatag
    61741 acgctatcgc taatagttcc ttcaatatct ccagattcat ctttgataaa ctcttcggga
    61801 cgaatgctta catgaatagc ttgctcctca acctgatcaa gagctggcat tcgaagggca
    61861 tagccatctg aaaagacgat ataagcgccg tcgctccgtt tttcaagatt ggcagggata
    61921 atatttgtgc gtccgataaa ggttgccaca aactcattag ctggtttatg atagagttct
    61981 tttggtcggc cgatttgttg gatcacccca tctttcataa cagcaatttg atctgaaata
    62041 gccatggctt cttcttggtc gtgggttaca taaacagttg taattcccac ttcgtgttgg
    62101 atttctcgga tggcttgacg catatccaag cgaagtttgg cctccagatt actaagtggc
    62161 tcgtccatga ggagaacact tggattaacc gctaaggcgc atgccaaggt gacacgttgt
    62221 tgttgtccac cactgagttt atcgggcttt cgatccgcat attgagcaat ttgcatgagt
    62281 tcaagatact tgttggtctg ttgaatcaat tcttcttttg gaaccttctt ttgcttaaga
    62341 ccaaaagcaa cgttgtctcg gacagtcaaa tgtgggaaaa tagcgtagtt ttggaaaacc
    62401 atcccgatat tgcgtttgct gggttccata ttattgattt ttgtatcatc gaagtaaaat
    62461 tctccatctt tgatactgtt gaaacctgca atcatacgaa gaagggtcgt tttcccacat
    62521 cctgaaggtc caagaagggt aaagagactt ccttttggaa ttgtaatgtt caaattctca
    62581 ataacaggga catcgtggta gattttttgg cgttaataat tttgatctca ctcatagtga
    62641 acctttttta ctgtttagat tggatatctg taaagacttc gttgtatttc ttaacgatat
    62701 ctgatttatt cttgatgaca taatcataat cttcagtgag tgttttgatt ttgtcaattg
    62761 gtttcatgtt ttcgcttgtt ttagcatttt tacgaacagg acggttagta gtggttgtac
    62821 caagtgtatc ttgtacttct tgagagataa taaaatcgat aaatttcttg tcattttcca
    62881 tatttttagc ttttttaacg atagcagcac tagcaggtag gaagacggtt ccttcttttg
    62941 gatagactac tttaatgtta gctccgtcat ttaagagttt aactgctgga tcctcataag
    63001 agagaccaac agccatttct ccatcaacga ctgctttata gacaccagat gaacttgaac
    63061 cgattttata gtgtattgaa actagaatag tacacctcta cttctaaaac attgttagaa
    63121 atcgatttga ctgtcctgat taatttgtcc tgttcttatt tcatttcact atgccatcaa
    63181 taagtgtgaa aagatctttt acataagacc aagccttatc atctttgtaa ccaccttgag
    63241 cttgtagcat atttgttaat tgagcaaagg cgctagaaga gtttgctggg tcagcagttg
    63301 cgatttttcc ttttagttca ggtttgagaa ggtcgctata tccttcgatg ttcatgcctt
    63361 tagttaaatc agggttgacg attaaaacac taccatctag tgtataagga gtagagaagc
    63421 cagttgtgtt ttgatattct ttgataacat tatcattttc ttttgaaata tagttttcaa
    63481 agagttctcc gtgggtagca tattgtgtat aagaaccacc aaagataaca tcagctacag
    63541 gaacttcttt ttctgactct agttttttga aaagttctcc agtaccagct tgaatcagtt
    63601 ctattttgat accatatttt tcttcaaagg caggaatagt tgctccaatt aagccttctg
    63661 agtttggtga ataaacgact agcgaaccac cgtctccttt atcagatgaa ctgtcatcgg
    63721 cagattcatt agaagaacaa gcagcataat acatctattt ctttttcatg atggatatct
    63781 ccgttgtgtt atttaagttt attttaaaac aatgtaagcg tttttaaaac ctacaattct
    63841 attctatagt gtattgaatc tataacagta cactttgact gctaaaatat ttctataaat
    63901 taatttgact ttcctgatag agatgttcac atcttatttc aattcactat attagagtaa
    63961 aattctctac aaaaagaaga atagcctatt tgactattct tccgagtgat ttcaatttct
    64021 ttggggaaat atggagatac tttttaaata ctttggcaaa atatttatag tctgaaaatc
    64081 caacttggtc agagatagcg cttaaagggg agttgggaga ttcagccatc ttatctatag
    64141 cttgtttcag gcgatattgt aagatatatt catttagagt catggggaag tcttctttga
    64201 taaccttata tagatgcttg ttatctgcaa atagctagag catttcaagg aaataaacta
    64261 gaaataacaa ttaatatggt ggttcagaaa taccttttga taatcaataa gatcttcagg
    64321 atgaagtgcg ttgattccat ccatttcata tttccgattt aataaacgat atttgttttc
    64381 accaaattga tgaaaaggga gtagttgaac ttggtcgata tttaatgagt taaatagagt
    64441 agcgaatttt tctgcatcct ctaaactatt gttaaaatta ggaataactg ggattcttaa
    64501 aacgatagtt ttattttgag aaaaagcata atgaatgttt ttaataatca tttgattaaa
    64561 aaccccagtc acttttttat gttttataga attataatgt tttaggtctg tgtagataaa
    64621 atccacatat tgaattaaat caataaattt ttcatgatca acaaaggcag tagtttcaat
    64681 ggcagtgtgt atgtgatgtt ctttagctga ttttaagatg gctttagcaa attcaaactg
    64741 agcaaatatt tcacctcctg ataaagttaa acctccaccg gattcttcgt aaaattcttt
    64801 gtcttttaat acctctgtaa taatttcttc tacagtcttt tcttcaccga ctaaggtgaa
    64861 tttctctcgt tgagcatctt tcattttttc aggtttcatt ctttgagatt caggattaga
    64921 acaccatgga cagcgcagag gacatccttt taaaaaaaca gttgtacgaa tacccgggcc
    64981 gtcatgaatt gaaaagtgtt gaatattaaa aataattcct ttagatattt ccataagagt
    65041 tcctcctctt cataagtcta tcctatcaca aaaacgaaag aaaaacaatt acgaacgaaa
    65101 gtttaatttg ttgttttttg ctttttattt tggtagaata aaacggaggt gtaaaatgaa
    65161 aagattggaa caaattatta aattagtatc agaatatgaa aagatcgacg ttaatacatt
    65221 atcggaaaaa ttaaatgtat cgaaagtaac gattagaaaa gatttagata aattagagtc
    65281 aaaaggttta ttacacagag agcatggata tgctgtatta aatagtggag atgacttaaa
    65341 tgtacgtttg tcaattaact atgaaattaa gagaaaaatt gttcaggaag cagtaaaatt
    65401 ggtgtcagat aatgaaacaa taatgataga atctggatcg acctgtgctt tacttgctga
    65461 ggaaatttgc aagcaaaaaa gaaatgttac gattgtaaca aattcatttt ttatagcaaa
    65521 ttttgtgaga gcttatgatt catgtcgtat tattgttctt ggtggagagt ttcagaagga
    65581 ttcacaggtt actgtgggac ctttattaaa agaaatgata cagacttttc atgtgcatca
    65641 agcttttgtt gggacagatg gttacgataa agagatgggc tttacaggaa aagatttaat
    65701 gcgcagtgag gtagttcaat atatttcagc agcgtcggat aaagtcattg tactaactga
    65761 ctcaagtaaa tttgataaaa ggggtacagt aagaagattt gctttaagtc aagtctatga
    65821 agtaataaca gacgaaaaac tttctaaaca aaatatagct acattagaaa atgctgggat
    65881 aatggttaag gtagtttcgt aagaggttaa atgtatgaat caagatagga ataaactgct
    65941 ctctaaaatt gcttatctgt attatattga aaacttaaat cagtcacaaa tagcagcaaa
    66001 attaggaatt tatagaacct ctattagtag aatgttaaca gaagcaagga atgcaggaat
    66061 tgttaaaatt gaaatagaga attttgatac caatatgttt aagttggaaa attatgtaaa
    66121 agaaaaatat ggtctggaaa gtttagaaat tattccaaat gaatttgatg ataatccaac
    66181 aattttatct gaaagaattt ctcaagttgc agcaggtgtc cttaggaatc taattgatga
    66241 taatatgaaa attggctttt cttgggggaa aagtttaagt aatttagtag atttaattca
    66301 cagtaaaagt gtccgaaatg ttcacttcta tcctctagca ggtggtccta gtcacataca
    66361 cgctaaatac catgtgaata cactgattta tgaaatgtct agaaaatttc atggagagtg
    66421 tacatttatg aatgcaacga ttgtgcaaga aaataaattg ttagcagatg gtattttgca
    66481 atcaagatat tttgaaaatt tgaaaaatag ttggaaagat ttagatatag ctgtagtcgg
    66541 aattggtgat tttagcaata aaggaaagca tcaatggtta gacatgctta cagaggatga
    66601 ctttaaagaa ttgaccaaag ttaaaactgt aggagaaatt tgttgtcgat tttttgattc
    66661 aaaaggtaaa gaagtctatg aaaacttaca ggaaagaacg atagcaatct ctttggaaga
    66721 tttaaaaaat attcctcaaa gtttagctgt tgcttacggt gatacgaaag tatcttcgat
    66781 tctttctgtc ttgcgtgcta atttagtaaa tcatttgatt acagacaaaa atacaatttt
    66841 aaaagttttg gaagaagatg gggatttgac ttttagagag attctaggtg agtgaaaatg
    66901 atagactgat cagtttatcg ttttttcttt ttagtcgatt gcacatttgt gctcatataa
    66961 acaaaaatag tttatctgtt gtttttggat tgacaacttt attatgtagt tgtattctat
    67021 agttacaaaa gaaaatttta aaatttcaaa tgaaaaaagc tttttacata gtgaaatgag
    67081 gaggaattta tggaaattat tgttccagat caaattatca tgggtttaat tttatatgct
    67141 ggtgatgcga aacaacatat ttataaagcg ttagattaca taaaaaatgg tacatgtgaa
    67201 cggtgtgaag aagaaatcca gttagctgat gccgccttat tagaagccca taatctacaa
    67261 acaaaattct tggcacaaga agcgtctggt acaaagacag aaattacagc tctctttgtt
    67321 cattcacaag atcatctcat gactagtatg acggagatta atttaatcaa agaaattatt
    67381 agtttgagaa aagaacttca taaaaaataa tactagagta ttatcattgt tattaacata
    67441 gaggaggaaa acataatggt gaagattggt ttgttttgtg cagcaggttt ttctactggt
    67501 atgcttgtaa ataatatgaa aattgcagcg caagctagtg gagttgaggc agaaatagag
    67561 gcgttttctc agtctaaatt agcggattat gcgccaaata tagatgttgc actattgggt
    67621 ccacaagttg cttatacatt agataaatca aaagaaattt gtgataagtg tgatgttccg
    67681 atagctgtta ttccgatgat ggactatggt atgttagatg gaaaaaaagt attagatttg
    67741 gccctatctt tgattagtgg gtaagaaaag gagatttatt atggcaaaga tggatgttca
    67801 gaaaatcatt gcaccgatga tgaagtttgt gaatatgcgt ggcattatag ctctaaaaga
    67861 tgggatgtta gcaattttgc cattgacagt agttggtagt ttattcttga ttatgggaca
    67921 attgccgttc gaaggattaa ataagagcat tgctagtgtt tttggagcta attggacaga
    67981 gccgtttatg caagtatatt caggaacttt tgctattatg ggtctaattt cttgtttttc
    68041 aattgcctat tcttatgcta agaatagcgg agtagaggct ttaccagctg gagttctatc
    68101 tgtatctgca ttctttattt tgctaagatc atcttatatc cctaaacaag gtgaggcaat
    68161 tggggatgct attagtaaag tttggtttgg aggtcaagga attatcggtg ctatcattat
    68221 aggtttggta gtaggaagta tttatacctt ctttataaag agaaaaattg ttattaagat
    68281 gccagaacaa gttccacaag ctattgccaa acagtttgaa gcaatgattc cagcatttgt
    68341 aattttctta ctttctatga ttgtatatat tttagcgaag tcattgacta atggcggaac
    68401 attcatagaa atgatttatt ctgctattca agttccattg caaggtttaa ctggatcttg
    68461 gtatggtgca attggaattg cattctttat atcatttttg tggtggtttg gtgttcatgg
    68521 acaatcggta gtaaatggag tagtgacagc tctgctttta tctaatcttg atgctaataa
    68581 agctatgtta gcctctggta atctatcatt agaaaatggt gcacatattg ttactcaaca
    68641 atttttagat tcatttttaa ttctatcagg ttcagggatt acgtttggtc ttgtagttgc
    68701 catgcttttt gcagcaaaat caaaacaata ccaagcctta ggaaaagttg ccgcttttcc
    68761 agcaatattt aacgtaaatg agccagttgt atttggattt ccgattgtca tgaatccagt
    68821 tatgtttgta cctttcattc ttgttcctgt acttgcagct gtgatagtat atggagctat
    68881 tgcaacaggt ttcatgcagc cattctcagg ggtaacattg ccttggagta caccagctat
    68941 tttatcagga tttttggtgg gtggatggca aggagttatt actcagctgg tgatattagc
    69001 gatgtctaca ttggtttatt ttccattctt taaagtacag gatcgtttag cttaccaaaa
    69061 tgaaatcaaa caatcttaga ggtatttgtg tgttactgtt aaactcacac atttgtgcta
    69121 aaaattagag agttaaaatt tttctagtta aaagcttgaa aatttctata aaaatcggta
    69181 ttatattttc gaaagaaata aaaatatttt cgaaagaaag gtggttacga tggtaaatac
    69241 agaagtagca agaacaacaa tcaagacaga atattttggc agccttactg aaaggatgaa
    69301 caaatatcga gaagatgttt taaataaaaa accttatatt gatgctgaga gagcagttct
    69361 agcaacacgc gcctatgaac gatacaagga acaacctaat gtcctaaaac gtgcatatat
    69421 gctgaaagaa attttggaaa atatgactat ctatattgaa gaagaatcta tgattggggg
    69481 aaatcaagct tcttccaata aagatgctcc tatttttccg gaatatacgc tagaatttgt
    69541 tctcaatgag ttggatcttt ttgaaaagcg tgatggagat gttttctata ttacagaaga
    69601 aacaaaagaa caacttagaa gtattgctcc gttttgggaa aataataatt tacgtgctag
    69661 agctggtgcc ttattacctg aagaagtgtc tgtttatatg gaaacaggat tcttcggtat
    69721 ggaaggtaag atgaattctg gagatgctca cctagcagtt aactatcaga aacttttgca
    69781 atttggctta agaggttttg aagagcgggc tcgtaaagca aaagcagctc tagatttaac
    69841 agatccagca agtattgata aatatcattt ttacgactct atatttatcg taatcgatgc
    69901 tattaaagta tatgcaaagc gctttgttgc tcttgctaaa agtttagccg aaaatgcaaa
    69961 tcctaaacgt aagaaagaat tacttgagat tgcagatatt tgctctagag tcccatatga
    70021 accggcaact acttttgcag aagctattca atcagtttgg tttattcaat gtattttaca
    70081 aattgaatct aatggccact ctctttcata tggccgtttt gatcaatata tgtatccata
    70141 tatgaaggct gatttagaaa gtggtaaaga aacagaagat agcattgttg aacgtctgac
    70201 aaatctttgg attaagacaa ttacaattaa taaggttcgc agtcaatcac atacattttc
    70261 ttcagcagga agtcctttat atcaaaatgt tacaattggt ggacagactc gagataagaa
    70321 ggatgctgtt aacccattat cttatttggt attaaaatca gttgcacaaa cccatctacc
    70381 gcaacctaat ctaactgtac gttaccatgc aggtttagat gctcgtttca tgaatgagtg
    70441 tattgaagtg atgaaacttg gttttggtat gcctgcattt aataatgatg agattattat
    70501 tccttctttt attgcaaaag gagtattgga agatgatgct tatgattaca gtgccattgg
    70561 atgtgttgaa acggcagttc cagggaaatg gggctatcgt tgcacaggta tgagttatat
    70621 gaacttccct aaggttctac ttatcacgat gaatgatgga attgatccgg cttcgggtaa
    70681 acggtttgca ccaagctttg gtcattttaa ggatatgaag aacttttctg aattagaaaa
    70741 tgcttgggat aaaacactaa gatatttgac acgaatgagt gttattgttg aaaattctat
    70801 tgatttatca ttggaacgag aagttcctga tattctatgt tcagcattga ctgatgattg
    70861 tattggtcgt ggaaaacacc ttaaagaagg tggagcagta tatgattata tatcaggatt
    70921 gcaagttgga attgcaaatt tgtcggattc attagctgca attaaaaaat tggtgtttga
    70981 ggaagaacgt ataagcccaa gtcagctttg gcatgcattg gaaacagatt atgccggaga
    71041 agaaggtaag gtcattcaag aaatgttgat tcatgatgca cctaagtatg gtaatgatga
    71101 tgattatgct gacaaattgg ttactgctgc ttatgacatt tatgttgatg aaattgctaa
    71161 atatcctaat acacgttatg gaagagggcc tattggagga attcgttatt caggaacatc
    71221 ttctatatca gccaacgtag ggcagggacg tggaacatta gcaactccag atggacgcaa
    71281 cgcgggtaca ccgttagcag agggttgttc accatcacat aatatggatc aacacggccc
    71341 tacatctgtt ttaaaatctg tttcaaaatt accaacagat gaaatcgtag gtggggttct
    71401 cttaaatcag aaagtaaatc ctcaaacgtt agccaaagaa gaagataaat taaaactaat
    71461 tgctttgtta cgaacattct ttaatcgttt acatgggtac catattcaat acaatgttgt
    71521 ttccagagag acgttgattg acgctcagaa acatcctgaa aaacacagag acttaattgt
    71581 tcgtgttgca ggatactctg cattcttcaa tgttctttct aaggcaaccc aagatgacat
    71641 tataggacgt actgagcata ctttgtaaaa taaagaggtt ctttttatgg aatttatgct
    71701 tgacacatta aatttagatg agattaaaaa gtggtctgaa attttgccgc tagctggggt
    71761 aacttcaaat cccactattg caaaaagaga gggttctatt aatttttttg aacgaatcaa
    71821 agatgtaaga gaattgattg gctccacacc ctctattcat gttcaggtga tttctcaaga
    71881 ttttgaaggc atcttaaagg atgctcatga aattcgaaga caagcaggag atgatatatt
    71941 tatcaaagta cctgttactc cagctggatt acgtgcaata aaggtgctaa aaaaagaggg
    72001 ctaccatatc actgcaacag ctatttatac agttattcag ggattattag ctatcgaagc
    72061 aggagcggat tacctagctc catattataa tagaatggaa aatctgaaca ttgattcaaa
    72121 ttctgtcatt cgtcaattag ttcttgctat tgatagacag aactctccta gtaagatttt
    72181 ggctgcatcc tttaaaaatg tagcacaagt aaataatgct ttagctgcag gtgcgcatgc
    72241 tgttacagca ggagcagatg tttttgaatc agctttcgcc atgccatcta tccaaaaggc
    72301 ggttgatgat ttttctgacg attggtttgt tactcaaaat agtcgttcca tttagataga
    72361 gaggaaatac atatgagaat ttttgctagt ccttctagat atattcaggg ggaaaatgcc
    72421 ttgtttgaaa atgccaaatc aattttggat ttgggaaatt accctattct attatgcgat
    72481 cagttggttt atgatattgt tggaaaacga tttgaagatt atctacatag gtatggtttc
    72541 catattgttc tggcgctatt taatggtgaa gcttctgaca atgaaatcaa tcgagttgtt
    72601 gccttggctg agaaagaaaa ttgtgatagt attatcggtc ttggtggggg aaagacgatt
    72661 gatagcgcaa aagctattgc agatttgatt gaaaagcctg ttattattgc tccaacaatt
    72721 gcatcgaccg acgcacctgt atctgcttta tctgttattt atacagatga aggtgcattt
    72781 gatcattatc tattttattc taaaaatcca gatttagttt tggttgatac aaaagttatt
    72841 tcacaagccc ctaagcgttt attagcgtct ggtattgcag atggtttagc aacttgggtt
    72901 gaggcgcgtg cggttatgca ggcaaatgga aaaactatgt tgggacaaca gcaaacattg
    72961 gctggagttg caattgcgaa gaaatgtgaa gaaacgctgt ttgcagatgg tttacaggct
    73021 atggcagctt gtgaagctaa agtggtgaca ccagcattag aaaatattgt tgaagctaat
    73081 actttattga gtggtctagg ttttgaaagt ggaggattag ctgcggcgca tgcaattcat
    73141 aatggtttta ctgcattgac aggtgacatt catcatttaa cacatggtga aaaagtagct
    73201 tatggaactt tagtacaact attattggaa aatagaccta aagaagaact tgataagtat
    73261 attgagtttt acaaaaaaat tggtatgcca acaactctaa aagaaatgca tttggatcaa
    73321 gttggatatg atgatttaat aaaagttggt aaacaagcaa ctatggaggg tgagacaatt
    73381 catcagatgc cgtttaagat ttcgccttca gatgttgctc aagctattat cgctgtagat
    73441 gcctatgtaa attcaaaata aacaataagg actactgttt tccaaatggt agtcttttat
    73501 tgatccccgt attgaattct atagaagatt gaaataggat gagaacaaat cgattgggaa
    73561 agtaaaatta atttctataa atgttttagc aattgtttcg tactatttca gattcagtct
    73621 actatacgtt cttcataaat caaaaagcga cataggttgt cggctattta ttgtgaatac
    73681 attaattagc attccagttt tatcttcggt ctaaaataag tattttgtgc tatacgagat
    73741 aagcgtcttg acttactcct tgatttactg cataacaatg ggataaaaag tgggagatag
    73801 agcaattcat agtcatcaaa attaatgaga tacagtatac agtttttcct ttaaacacat
    73861 ttcaaattcc ctcaaaaatg gtataatagt aacatcacaa aattggagag agaccatgag
    73921 tttttacaat cataaagaaa ttgagcctaa gtggcagggc tactgggcag aacatcatac
    73981 atttaagaca ggaacagatg catcaaaacc taagttttat gcgcttgata tgttccctta
    74041 tccgtctgga gctggtctgc acgtaggaca cccagaaggt tatactgcaa ccgatatcct
    74101 cagtcgttac aaacgtgcgc aaggctacaa tgtccttcac ccaatgggtt gggatgcttt
    74161 tggtttgcct gcagagcaat acgctatgga tactggtaat gacccagcag aatttacagc
    74221 ggaaaacatt gccaacttca aacgtcaaat caatgcgctt ggattttctt atgactggga
    74281 tcgtgaagtc aatacaacag atccaaacta ctacaagtgg actcaatgga ttttcaccaa
    74341 gctttacgaa aaaggcttgg cctatgaagc tgaagtgcca gtaaactggg ttgaggaatt
    74401 gggaactgcc attgccaatg aagaagtgct tcctgacgga acttctgagc gtggaggcta
    74461 tccagttgtc cgcaaaccaa tgcgccaatg gatgctcaaa atcacggctt acgcagagcg
    74521 cttgctcaat gacttagatg aactagattg gtcagagtct atcaaggata tgcaacgcaa
    74581 ctggattggt aaatcaactg gtgccaatgt aactttcaaa gtaaaaggaa cagacaagga
    74641 atttacagtc tttactactc gtccggacac acttttcggt gcgactttca ctgtcttggc
    74701 tcctgaacat gaattagtag acgctatcac aagttcagag caagcagaag ctgtagcaga
    74761 ctataaacac caagccagcc ttaagtctga cttggttcgt acagaccttg ctaaggaaaa
    74821 aactggtgtt tggacaggtg cctatgccat caaccctgtc aatggtaagg aaatgccaat
    74881 ctggattgcg gactatgttc ttgctagtta tggaacaggt gcggttatgg ctgtgcctgc
    74941 ccacgaccaa cgtgactggg aatttgccaa acaatttgac cttccaatcg tcgaagtact
    75001 tgaaggtgga aatgtcgaag aagctgccta cacagaggat ggcctgcatg tcaattcaga
    75061 cttcctagat ggattgaaca aagaagacgc tattgccaag attgtggctt gcttggaaga
    75121 aaaaggctgt ggtcaggaga aggttaccta ccgcctccgc gactggctct ttagccgtca
    75181 acgttactgg ggtgagccaa ttccaatcat tcattgggaa gatggaactt caacagctgt
    75241 tcctgaaact gaattgccgc ttgtcttgcc tgtaaccaag gatatccgtc cttcaggtac
    75301 tggtgaaagt ccactagcta acttgacaga ttggcttgaa gtgactcgtg aagatggtgt
    75361 caaaggtcgt cgtgaaacta acaccatgcc acaatgggct ggttcaagct ggtactacct
    75421 ccgctatatt gacccgcaca atactgagaa attggctgat gaggacctcc tcaaacaatg
    75481 gttgccagta gatatctacg tgggtggtgc ggaacatgct gtacttcact tgctttatgc
    75541 tcgtttctgg cataaattcc tctatgacct cggtgttgtt ccgactaagg aaccattcca
    75601 aaaactcttt aaccaaggga tgattttggg aacaagctac cgtgaccacc gtggtgctct
    75661 tgtggcaacc gacaaggttg aaaaacgtga tggttccttc tttcatatag aaacagggga
    75721 agagttggag caagcgccag ccaagatgtc taaatcgctc aagaacgttg ttaacccaga
    75781 tgatgtggtg gaacaatacg gtgccgatac ccttcgtgtt tatgaaatgt ttatgggacc
    75841 actcgatgct tcgattgctt ggtcagaaga aggtttggaa ggaagccgta agttccttga
    75901 ccgagtttac cgtttgatta caagtaaaga aatccttgcg gaaaacaatg gtgctcttga
    75961 caaggcttac aacgaaacag tcaaagctgt tactgagcaa attgagtctc tcaaattcaa
    76021 cacagctatt gcccaactta tggtctttgt caatgctgct aacaaggaag ataagcttta
    76081 tgttgactat gccaaaggct ttattcaatt gattgcacca tttgcacctc acttggcaga
    76141 agaactctgg caaacagtcg cagaaacagg tgagtcaatc tcttatgtag cttggccaac
    76201 ttgggacgaa agtaaactgg ttgaagacga aatcgaaatc gttgtccaaa tcaaaggtaa
    76261 agtccgtgcc aaactcatgg tcgctaaaga cctatcacgt gaagaattgc aagaaattgc
    76321 tctagcggat gaaaaagtca aagcagaaat tgacggtaag gaaatcgtga aagtgattag
    76381 tgtaccaaat aaattggtta atattgttgt aaaataacca atttatttgc tgatttccaa
    76441 cctcaaacag tttcccaaac tgtttgagcc aactaaactc gttaatatcg ttgtgaaata
    76501 aggtaggaat ccttcagagt agaatctgga ggattttttg aatcttctta tgaaagtatg
    76561 gtatactatg ggcaactata aagtttgaaa agtgaaaaaa ggagaaagct atgccagtaa
    76621 atgaatatgg tcaaatgatt ggggagtcaa tggaaggtta tacaccaggt gaactgcctt
    76681 ctattgattt cttagaaggg cgttatgcta ggatagaggc tctttcagtg gaaaagcatg
    76741 cggaggattt gctagctgtt tatggcccgg atactcctcg ggagatgtgg acctaccttt
    76801 ttcaggagcc agtagcagat atgggggagc tggttagcct tttacatcag atgttggctc
    76861 gtaaggaccg tttttactat gcaatcatag acaaggcgac tggtaaggct ttgggatctt
    76921 tttctctcat gcgcattgac cagaataacc gagtaataga agtcggagca gtcacttttt
    76981 ctccagagct aaggggtaca cggataggaa ctgaagctca gtatctccta gctcgctatg
    77041 tttttgagga gctaaactat cgtcgctacg agtggaaatg cgatgcctta aatctgccat
    77101 ccagacgagc tgcggagcgt ttgagcttta tttatgaagg aaccttccgt caggcagtgg
    77161 tttataaggg acgtacgaga gatacggatt ggttgtctat gattgataag gactggcctc
    77221 aagtcaaaga tcgtttggaa acatggttgc gtcctgaaaa ttttgataaa aatggacagc
    77281 agtacaagag cttgagagaa ctttaagagg tgttgagatg attactatta aaaagcaaga
    77341 aattgtcaag ctagaggatg ttttacatct ctatcaggct gtcggttgga caaattatac
    77401 ccatcaacca gagatgctgg agcaggcctt atctcattca ttagtaattt atctggcact
    77461 tgatggtgat gctgtggtgg gcttgattcg tttggttgga gatggattct catcagtatt
    77521 ggttcaggat ttaatcgttt taccaatcta tcagcgtcaa ggaattggta gtgccttgat
    77581 gaaagaggct ttagaggatt acaaagatgc ctatcaagtc cagctggtga cagaagagac
    77641 agaaagaacc ttgggcttct atcgttctat gggctttgaa atcttatcca cctataattg
    77701 tatagggatg acttggatga atcgtaaaaa ataacaaaac ttgttttttc ttaagcaaaa
    77761 tttaaggatg gtctagtatt atatagtcat taaataaaga cctcctaact ttatttaata
    77821 aaatcctaaa cttttttcat cacaatctcc taatgaagcc acccaatcag gtggcttttt
    77881 tgcgtggtga ggtgctggtg atagaaattt tttgcaaaat agtaaaattt tagaaaagtt
    77941 aagctagttt taagtttcgt cttgtatcat gtagttatta aataaagacc tcctaacttt
    78001 atttaataaa atcctaaact tttctttttc ataataatct cccttaactt cacccaatca
    78061 ggtggagttt tttagctcta tttcaggctt ttggggacta ttctaaaaat aatttttcga
    78121 tatttttcgg tatttttcgg attttggtcg gggaattggc ggggactttt ttagcgaata
    78181 taactaagaa ataggtctgt ggtcgcttca gctagttcaa actcaatttg attgtaagtg
    78241 actgttaatt gaagaactgg aactactgta ataatgattt tgcttgtcta gtagtggcgt
    78301 attaaatgag aagtaacatg taagattgtc tcttcgttta cgaaatcaaa atttctatga
    78361 aattgataga atccctaacg ttctcttaat cttaaccgtc ttgtcgtaca gcggttgaag
    78421 aaaatgtaaa cctttgacaa aattcgtgaa ctatgggata ataaaaagga attgagtact
    78481 agttctatat cataggctag aaaagacccc aagctcacga ccaaataagc ttgaggtctt
    78541 ttttgacact atttgtcctt gtttagccat ttatcgacta tacgaagaac gacaccgacc
    78601 acaattggtc cgatgatagt tttgagtact aattccatca tgggctatct cacctccttt
    78661 cgtaggcggt gtagcagtgt cgtagaatat tataccacat aagtgctaaa cttaggagtc
    78721 acccaatcag gtggcttttt tgtttgtggc ttggtttttt gatataatag agccatgagt
    78781 agaattttag ataatgagat aatgggggat gaggagttag tagaacgcac gctccgtcct
    78841 cagtatttac gtgaatatat cggacaggat aaggtcaagg accagctaca aatctttatt
    78901 gaagctgcca aaatgcggga tgaagcgctg gatcatgtgc tcttatttgg gcctccaggt
    78961 ctcgggaaaa cgaccatggc ctttgttatt gccaacgaac tgggagtcaa tcttaagcag
    79021 acgtcgggtc cagtcattga aaaagccgga gatctggtag ctattttgaa tgagttagag
    79081 cctggggatg tactttttat tgatgagatc catcgtttgc caatgtcagt ggaagaggtg
    79141 ctttatagtg ctatggagga cttctacatc gatattatga ttggggctgg tgagggtagt
    79201 cgtagtgttc atttggagtt accacctttt accttgattg gtgcgacgac tcgggctggt
    79261 atgctctcca atccgctacg ggcacgtttt gggattacag gccatatgga gtattatgcc
    79321 catgctggct tgacagaaat tgtcgagcgg acggcagata tttttgagat ggaaatcact
    79381 catgaggcag catctgagtt ggccctacgt agtcgtggga cccctcgtat tgccaatcgt
    79441 ctcctcaagc gcgtgcgcga ttttgcccag ataatgggga atggggtaat tgatgatatt
    79501 attaccgata aggctttgac tatgctggat gttgaccatg aaggtttgga ctatgtggat
    79561 caaaaaatcc ttcgtaccat gattgagatg tacagtggag gacctgttgg tctaggaact
    79621 ctttctgtga atatcgccga agagcgtgag acagttgaag atatgtatga gccttacttg
    79681 attcaaaaag gttttatcat gcggacacgg tctggacggg tggcgactgc taaggcatat
    79741 gagcacttag gttatgaata cagtgaaaaa taagcaagaa atcttagagg cttttagaga
    79801 aaatccagat atgatggcca ttctgacgat catccgagac cttggtctga aagactcgtg
    79861 gttggcagca ggttctgtca gaaatttcat ttggaatctt ttgtcagaca aatccccttt
    79921 tgatcatgaa acagatatag atgtgatttt ctttgatcca gatttttctt atgaggaaac
    79981 cttattactg gagaaaaagc tgcgagagga ttttcctcag taccagtggg aattgaaaaa
    80041 tcaggtctat atgcatcagc acagtcctca cactgcttcc tataccagtt ctcgtgatgc
    80101 tatgagtaag tatccagaac ggtgtacgac agttggactg cgcttgaatg aagaatcaga
    80161 ttttgaactc tatgcacctt atggtttgga ggatattttg aattttcaag ttcgtccaac
    80221 tcctcatttc ttagaaaatg aagaccgaat ggaactctat caaacacgtt tatccaagaa
    80281 aaattggcag gagaaatgga aaaatttgat ttttaaaaat acttaaggaa actttaagct
    80341 agggagtgta cactaagttc ataagttaag aagaccttaa cttaaactcc taaaactttt
    80401 tcataataat ctccctataa aaataaagtc gcctaatcag gcggcttatt tttttgaaaa
    80461 atgggcttgg tgcctgagaa taaatagctt agtgatagaa gaaaatgggg aaatatggta
    80521 taatgaaacg atagattttt gaataggaat aagatcatgt ttggattttt taagaaagat
    80581 aaggctgtgg aagtagaggt tccgacacag gttcctgctc atatcggcat catcatggat
    80641 ggcaatggcc gttgggctaa aaaacgtatg caaccgcgag tttttggaca caaggcgggc
    80701 atggaagcat tgcaaaccgt gaccaaggca gccaacaaac tgggcgtcaa ggttattacg
    80761 gtctatgctt tttctacgga aaactggacc cgtccagatc aggaagtcaa gtttatcatg
    80821 aacttgccag tagagtttta tgataattat gtcccggaac tacatgcgaa taatgttaag
    80881 attcaaatga ttggggagac agaccgcctg cctaagcaaa cctttgaagc tttaaccaag
    80941 gctgaggaat tgactaagaa caacacagga ttgattctta attttgctct taactatggt
    81001 ggacgtgctg agattacaca ggcgcttaag ttgatttccc aggatgtttt agatgccaaa
    81061 atcaacccag gtgacatcac agaggaattg attggtaact atctctttac tcagcatttg
    81121 cctaaggact tacgagaccc agacttgatt atccgtacta gtggagaatt acgtttgagc
    81181 aatttccttc catggcaggg agcctatagt gagctttatt ttacggacac cttatggcct
    81241 gattttgacg aagcagcctt gcaggaagct attcttgcct ataatcgtcg ccatcgccga
    81301 tttggaggag tttaggagga aatatgaccc aggatttaca gaaaagaacc ttgtttgcag
    81361 ggattgccct ggctattttc ctaccaattt taatgattgg gggcctcttg cttcagatag
    81421 caatcggaat catagccatg ctagccatgc atgaactttt gaagataaga ggtctagcga
    81481 ccatgacgat ggagggcctc ttgactctct ttgcaacctt tgcattaacc attcccttgg
    81541 agaattacct gacttttttg ccagttgatg ggaatgtggt tgcctatagt gttttgattt
    81601 caatcatgtt aggaacgacc gtttttagca agtcttatac gattgaggat gcggttttcc
    81661 ctcttgctat gagcttctac gtgggctttg gatttaatgc tttactagat gctcgtgttg
    81721 caggtttgga caaggctctc ttagccttgt gtatcgtctg ggcgacagac agtggtgcct
    81781 atcttgttgg gatgaactat gggaaacgaa agttagcacc aagggtatcg cctaataaaa
    81841 cccttgaggg tgccttgggt ggtattttag gagcaatttt agtaaccatt atctttatga
    81901 tagttgacag tacagttgct cttccatatg gaatttacaa gatgtcagtc tttgctattt
    81961 tctttagcat tgctggacaa tttggtgatt tactagaaag ttcgatcaaa cgtcattttg
    82021 gtgttaagga ttctgggaaa tttatccctg gacatggtgg tgttttggat cgtttcgata
    82081 gtatgttgct tgtatttcca atcatgcact tatttggact cttttaatca aaagacggag
    82141 gaaacgctat gctcggaatt ttaaccttta ttctggtttt cgggattatt gtagtggtgc
    82201 acgagttcgg gcacttctac tttgccaaga aatcagggat tttagtacgt gaatttgcca
    82261 tcggtatggg acctaaaatt tttgctcaca ttggcaagga tggaacggcc tataccattc
    82321 gaatcttgcc tctgggtggc tatgtccgca tggccggttg gggtgatgat acaactgaaa
    82381 tcaagacagg aacgcctgtt agtttgacac ttgctgatga tggtaaggtt aaacgcatca
    82441 atctctcagg taaaaaattg gatcaaacag ccctccctat gcaggtgacc cagtttgatt
    82501 ttgaagacaa gctctttatc aaaggattgg ttctggaaga agaaaaaaca tttgcagtgg
    82561 atcacgatgc aacggttgtg gaagcagatg gtactgaggt tcggattgca cctttagatg
    82621 ttcaatatca aaatgcgact atctggggca aactgattac caattttgca ggtcctatga
    82681 acaattttat cttaggtgtc gttgtttttt gggttttaat ctttatgcag ggtggtgtca
    82741 gagatgttga taccaatcag ttccatatca tgccccaagg tgccttggcc aaggtaggag
    82801 taccagaaac ggcacaaatt accaagattg gctcacatga ggttagcaac tgggaaagct
    82861 tgatccaagc tgtggaaaca gaaaccaaag ataagacggc accgactttg gatgtgacta
    82921 tttctgaaaa ggggagtgac aaacaagtca ctgttacacc cgaagatagt caaggtcgtt
    82981 accttctagg tgttcaaccg ggggttaagt cagattttct atccatgttt gtaggtggtt
    83041 ttacaactgc tgctgactca gctctccgaa ttctctcagc tctgaaaaat ctgattttcc
    83101 aaccggattt gaacaagttg ggtggacctg ttgctatctt taaggcaagt agtgatgctg
    83161 ctaaaaatgg aattgagaat atcttgtact tcttggcaat gatttccatc aatattggga
    83221 tttttaatct tattccgatt ccagccttgg atggtggtaa gattgtgctc aatatcctag
    83281 aagccatccg ccacaaacca ttgaaacaag aaattgaaac ctatgtcacc ttggccggag
    83341 tggtcatcat ggttgtcttg atgattgctg tgacttggaa tgacattatg cgactctttt
    83401 ttagataatc gaggaatatt atgaaacaaa gtaaaatgcc tatcccaacg cttcgcgaaa
    83461 tgccaagcga tgctcaagtt atcagccatg ctcttatgtt gcgtgctggt tatgttcgcc
    83521 aagtttcagc aggtgtttat tcttatctac cacttgccaa ccgtgtgatt gaaaaagcta
    83581 aaaacatcat gcgccaagaa ttcgaaaaga ttggtgctgt tgagatgttg gctccaaccc
    83641 ttcttagtgc agaattgtgg cgtgaatcag gtcgttacga aacctatggt gaagaccttt
    83701 acaaactaaa aaaccgtgaa aaatcagact ttatcttagg tccaactcac gaagaaacct
    83761 ttacagctat tgtccgtgat tctgttaaat cttacaagca attgccactc aacctttatc
    83821 aaattcagcc caagtatcgt gatgaaaaac gcccacgtaa tggacttctt cgtacacgtg
    83881 agtttatcat gaaggatgct tatagtttcc acgctaacta tgatagtttg gatagtgttt
    83941 atgatgagta caaagcagcc tatgagcgta ttttcactcg tagtggttta gacttcaagg
    84001 ctattattgg tgacggtgga gccatgggtg gtaaggatag ccaagaattt atggccatta
    84061 catctgctcg tacagacctt gaccgctggg ttgtcttgga caagtcagtt gcctcatttg
    84121 acgaaattcc tgcagaagtg caagaagaaa tcaaggcaga attgctcaaa tggatagtct
    84181 ctggtgaaga taccattgct tactcaagtg agtctagcta tgcagctaac ttagaaatgg
    84241 caacaaacga gtacaaacca agcaaccgtg ttgtcgctga agaagaagtt actcgtgttg
    84301 caacgccaga tgttaaatca attgatgaag ttgcagcctt cctcaatgtt ccagaagaac
    84361 aaacgattaa aaccctcttc tacattgcag atggtgagct tgttgcagcc cttctagttg
    84421 gaaatgacca actcaacgaa gtcaagttga aaaatcactt gggagcagat ttctttgacg
    84481 ttgctagcga agaagaagtg gcgaatgttg ttcaagcagg atttggttca cttggaccag
    84541 ttggtttgcc agagaatatt aaaattattg cagatcgtaa ggtgcaagat gttcgcaatg
    84601 cagttgtcgg tgctaacgaa gatggctacc acttgactgg tgtgaaccca ggccgtgatt
    84661 ttactgcaga atatgtggat atccgtgaag ttcgtgaggg tgaaatttcc ccagatggac
    84721 aaggtgtcct taactttgcg cgtggtattg agatcggtca tattttcaaa ctcggaactc
    84781 gctactcagc aagcatggga gcagatgtct tggatgaaaa tggtcgtgct gtgccaatca
    84841 tcatgggatg ttacggtatc ggtgtcagcc gtcttctttc agcagtgatg gagcaacacg
    84901 ctcgcctctt tgttaacaaa acgccaaaag gtgaataccg ttacgcttgg ggaatcaatt
    84961 tccctaaaga attggcacca tttgatgtgc atttgattac tgtcaatgtc aaggatgaag
    85021 aagcgcaagc cttgacagaa aaacttgaag caagcttgat gggagctggt tatgaagtct
    85081 tgacagatga ccgtaacgaa cgtgtcggtg ttaaatttag cgatagtgac ttgattggtc
    85141 ttccaatccg tatcactgtt ggtaaaaaag cggccgatgg cattgtagaa gttaagatca
    85201 aggcaactgg tgacaccatt gaggttcatg cagataacgt gcttgaaacg cttgaaatcc
    85261 taagcaagaa ataaaaacta taatcagaag aaaaacaagg aaaaaatgta actagttttt
    85321 accttgtttt ttctgtataa tgggagaaat gagtagataa agaggtaaat gttatgctaa
    85381 gatttccaaa ggattttgtc tggggatcct ctacttctgg accgcagaca gaaggacgtg
    85441 tagctggtga cggtaaggga gacaatctct gggattactg gttccaagtg gagccaaatc
    85501 gttactataa tgggattggt tcagataaga catcgacttt ttatgaaaat tgggagcggg
    85561 atattgagct tttgttagag actggtcaca cagtctttcg gacttctatt cagtggtcac
    85621 ggatttttcc acaaggctgt ggaaaagtca accctcaagg tgtggatttt tatcgtaagg
    85681 tctttgaggc tattaaggct aaaggaattc gtctgttagt caatctctat cattttgatt
    85741 taccttttgc tcttcaagag gatggtgatg gttgggaaaa taaggcgaca gtctcagcct
    85801 atgaagacta tgctcgtttt tgttttgaga cttatggaga tttagtggat caatggatta
    85861 cctttaacga gcccatcgtt cctgtagaat ttggttattt ttatgatgcc cattatccac
    85921 ataaggtgga tgcagaggca gctgttaagg tagcctatca tacacaattg gccagcagcc
    85981 gggctgttaa ggcttgccat gaacttttgc ctgattccaa gattgggatt gtcctcaact
    86041 tgacaccggc ttatccacgt agccagcatc ctgctgatgt caaggcagct cgtattgcgg
    86101 ccctttttca ggcccaatct ttcttagatc catctgtctt ggggacttat ccacaggagt
    86161 tggtagaaat cttgcatgaa cacggtcttt tacctgatgc tacagaggaa gagttggaac
    86221 tcattcgtga taatacggtg gacttccttg gtgtgaacta ctatcaacct ttgcgtgtta
    86281 tggctcctcg atttgctaag catccagata gtccactctt accagaacat ttttacgagc
    86341 cttatgtgat gcctggacgt aaaatcaatt ctcaccgtgg ttgggagatt tatgagcaag
    86401 ggatttatga catcgcccaa aatatcaagg aaaattatgg caatattgag tggatgttga
    86461 ctgagaatgg tatgggtgtt gaaggggaag aaaaattccg tcaagatgga atgattcaag
    86521 atgattaccg tattgacttt gtaaaaggtc atcttcgtga acttcaccgt gccattgaag
    86581 atggtgccaa ctgtaagggc tacttgattt ggacctttat tgactgctgg tcatggctca
    86641 acagctataa aaatcgctat ggtttggtcg aattagactt ggaaacgcaa gaacgtcgtc
    86701 tgaagaaatc aggccactgg ttcaaagaat taagcgataa taatggattt taaaaaggac
    86761 tctgactgat tatcccaatc ggtcagagtt ttttgcttac aggagcttaa tttgaactat
    86821 accaattttt actcttgaca agtgaaagaa acaagtatat actgtttttg ctgattctat
    86881 aaaagatgaa ttagactata ccaattttaa ggagaaagca cagcttgcct gtgtcgtata
    86941 tactatgtgt ggaattgttg gtgttgttgg aaacacaaat gcaactgata ttttgattca
    87001 agggcttgaa aagcttgaat accgtggcta tgattctgcg ggaatttttg tcctagatgg
    87061 tgctgataac catttggtga aggctgttgg tcgtatcgca gaattgtctg ccaagacagc
    87121 tggtgttgag ggaacaactg gtatcggaca tactcgttgg gcaactcatg ggaaaccaac
    87181 ggaagacaat gctcacccac accgctctga gacagaacgt tttgtcttgg ttcacaatgg
    87241 ggtgattgaa aactaccttg aaattaaaga agaatacctt gctgggcacc acttcaaagg
    87301 gcaaacagat acggaaatcg ccgtacattt gattggaaaa tttgcggaag aagacggtct
    87361 ctcagttctt gaagccttta aaaaagctct tcatattatc cgtggttcat atgcctttgc
    87421 cttgattgac tctgaaaatc cagatgtcat ctatgtagcg aaaaacaaat ctccactttt
    87481 gattggtctt ggggaaggct acaatatggt ctgctcagat gctatggcta tgattcgtga
    87541 aaccaaccaa tacatggaaa ttcatgacca agagttggta atcgtcaagg ctgatagcgt
    87601 ggaagttcaa gactatgatg gtaacagtcg tgaacgtgct agctatactg cggaacttga
    87661 cttgtcagat atcggtaagg gaacttatcc ttactacatg cttaaggaaa ttgatgagca
    87721 accaactgtt atgcgtaaac tcattcaagc ctacacggat gatgctggtc aagtagtgat
    87781 tgatcctgct atcattaagg ctgttcaaga cgcagaccgc atctacatcc ttgcagctgg
    87841 aacatcttac catgcaggat ttgcttctaa gaaaatgttg gaagaattga cagatacacc
    87901 agttgaactt ggcatctcat ctgagtgggg ctacggtatg ccacttctca gcaagaaacc
    87961 actcttcatc tttatcagcc aatctggtga aacagcggat agtcgtcaag ttttggtcaa
    88021 ggctaatgaa atgggaattc caagcttaac agtgacaaac gttccaggtt caaccctctc
    88081 acgtgaagcc aactatacca tgctccttca cgcaggtcct gaaattgccg tggcatcaac
    88141 taaagcctat acagcgcaaa tcgcagccct tgccttcctt gcaaaagcag tcggagaagc
    88201 aaatggtaat gctaaagcgc aagcctttga cctggttcat gaattgtcaa tcgtagctca
    88261 gtctatcgaa tcaactcttt cagagaaaga aaccattgaa gccaaggttc gtgaacttct
    88321 tgaaacaact cgtaacgcct tttacatcgg acgtggtcaa gattactacg tagccatgga
    88381 agcaagtctc aaactcaaag agatttctta tatccagtgt gaaggttttg cggcaggaga
    88441 actcaagcac ggaaccattg ccttgattga agaaggaaca cctgtcttgg ctctcttgtc
    88501 agatccagtc cttgccaacc acactcgtgg aaatatccaa gaggtggcag cccgtggtgc
    88561 taaggtcctc actatcgcag aagaaaatgt tgctaaagat accgacgata tcgtccttac
    88621 gactgtacac ccttacctct caccaatttc aatggtcgta ccgacgcaat tggttgctta
    88681 ctttgcaacc ctccaccgtg gcctcgatgt ggataaacca cgtaaccttg ctaaatcagt
    88741 aacggtagaa taagctaaaa aagtctagtt atctaggctt tttctaatga gcaaattggt
    88801 tgcttgtact caagattcgt gttagaataa tttttcaaat tgaaggacag agatagacaa
    88861 ggagaatcac aatggtagaa ttgggaattt caacatttgg ggaaataacg gagcttgaag
    88921 ggactggaca aacttacagt catgctgaac gcattcgcca gttggtggca gagattgagc
    88981 tggctgacaa ggttggtttg gacgtatatg ggattggcga gcaccatcgg gcggattttg
    89041 cagtatcagc cccagagatt gtcctggccg ctggggcagt caataccaag aaaatccgtt
    89101 tgaccagtgc agtcagcatt ctgtcaagca tggatccgat tcgtttgttc caacagtatg
    89161 ccactatcga tgctttgtca aatggacgat cggagattat ggctggaagg ggctctttca
    89221 cggaatcttt ccctctgttt ggttatgact tgaaagacta cgactctctt tttgatgaga
    89281 aattagactt gcttcagtta gtcaatgaaa agaccaagtt agactggcaa ggtcgattga
    89341 ctcaaacgat tgctggtaaa gaagtttatc ctcgcccagt tcaggacaaa ttgcccttgt
    89401 ggatagctac aggtggtcat gtcgaatcaa cagtgaagat tgctcaggct ggtctaccga
    89461 ttgtatatgc tattattggt ggtaatccac gttattttaa aaagttgatt caggcttatc
    89521 gtgagattgg aagcgaagcg ggccatgctg acaaagactt gaaagtggga gcccattctt
    89581 gggggtggat tgcggaagat ggtgagcagg cggtgaaaga ttatttccat ccgactaagc
    89641 aagtggtgga tgctatttcc aaagaccgtc cgcactggca ggaattgcgt tatgagcaat
    89701 atttggagca ggtagggcca aatggcgcca tgtttgttgg caatccagat caggtggccg
    89761 aaaaattgat tcgcatgata gaggatttag gattggaccg cttcatgctt catctaccgc
    89821 ttggttctat gcctcatgac caggttctga gagctattga actcttcgga acacaagttg
    89881 cacccaaagt acgagcttat tttgctatga aagaggctta ataaaaaatc ctaatcaagt
    89941 ttattaggac aacaaatatt gtacaaaaat taatcccccg agctataatg cttgggggat
    90001 ttttctatag gagggctagt ttagttctct tttttatttt ttagtaagaa accgagacca
    90061 aggagcgcaa ggaggctgat tcctgcaaat aggagtttgt tttcgttttt gattcctgta
    90121 tttggaagtt cagcttgttt atctggggtt gcaggtatat tttccttgct agagttttct
    90181 accgattcgt ttcgaaccgc ttcttttaca gatgcttctt gtgcttcttg tgctggttgt
    90241 tcagcttgtg aatcagctgt agcttggcta ggtttatttt ccgcatcagc tactttggca
    90301 tctggtttag tagaatcagg tctagcttct ggagctgggt cttgatgtgc agggtgagaa
    90361 gcttcatttt gatgttcagg cttggaaggg gttgagtctg gtttctcttc tgcagttgac
    90421 tcatggctag ttccattttg agagactcga agaacagtag ctgtaagggc attcaatttc
    90481 aagccttttt cagtccattc aagtcctttc gggttggcaa ttttgactga tcctgcttgg
    90541 ttttcatctg ccaaaacttc cgcatttctt agatgtgcaa aggcagttcc caaattaaat
    90601 tcgcgagctt tttcatccgc attgacaaag actgcgtaga tatcgccgtt tggagcagtg
    90661 atttggtagc caatcactac atcctctttt tccacaccat tttggcctgg gacagtgatg
    90721 aggtggacac ggtctttgat atcttggaga ctcttaagtc ggaaggcatc tgtagattga
    90781 cgaagggcaa tcaaaccttt catatagtca cggctcttga cattttcagg ataagcttta
    90841 ccatctgtag ccttagtcca gtcaaacttg ttgactgcgt cgctagaatc gtaagaatca
    90901 tggatgaagt aaggatagtc aaatgggttg ccgtccttat cacgcaacaa gtgagatttg
    90961 tttggaacct tatcctctgc tactggagtc ttgtaggctg ggtcacggaa ttgtttagta
    91021 cgtccatatt cctgaccgga gtggataaat ggagttcctt gagctgtcaa gaccatgaga
    91081 tttccaagtc gtaaacgacg gtggatttca gcatagttct cagccttgct tgggtctttt
    91141 ttgatagact gggcaatgat gtcaaagagg gtcaagttat catgggctgc tatgtattgg
    91201 atgacatctc cagggctgtc agcttcaaag ttagttggtt gagcaatgag atttttaaag
    91261 atggtgttga catcacgctt gccacctgtg ataaaggcag gttgaccttc gtttggataa
    91321 ccagatttga ggttgttacg gatgtcatct gaaaagacag cgacagtatc ggtatgtttc
    91381 atccaatctt ggtcagcagc tttagtaggc atgttttcat caccggcata ggttctccaa
    91441 ccttcaccaa gcatgatgag gtttggattg agggcgcgtg cagccttgta agcttcttcg
    91501 atagaagcgg cgtcatggtc tcccatcata tcgaaacgga atccatccac tttgtaggta
    91561 tcaactaggt atttgataga gtcaactagg agccgtttgg tcatatggtg ggttgttccc
    91621 aagcgtccac caccaaagct agttcgaggt gtgccatcgg catccataaa gtggtagtag
    91681 tttggctcta ggtcttcaaa gatatcgact ttggctgtgt ggttataaac gacatctagg
    91741 atagctccca taccacgttt gtggatttcg ttgatgaggt ttttaaattc tgcgattcgt
    91801 ttttctggat tcttaggatc gcttgagtac ataccagtca aggagaagta gttttgaggg
    91861 tcatatcccc agttgtagtt gctgttgctt gaagcgtagt cagacaagcg ttcatggttt
    91921 ttcaattcat tgacaaagta gtaagacaag actggaagga gctggatatg ggttacaccc
    91981 aagtctttga gatagtctag tttttcaatg aaggcttcaa aagtcccaaa tggtttggtc
    92041 aagtcttttg caatggcagg atctgaagtg aagtcacgca catgagcttc gtagataacg
    92101 gcgtcttcac gagtcttgaa attgtgaatc ttaccataag tcaagtcttg aggtccgagt
    92161 ttagctggat ctacaaaggc ggctttagcc actttatggg tatcgtcaat tttggcatcg
    92221 tcgctattcc aagcagcaag agatttagcg taaggatcga gtgcaagaac agttttacct
    92281 tgacgctcga tttggtattg ataatagtag ccagtgaaat ctgtgattcc gagtttgttt
    92341 gtgctgtcta gagtttgttt ccaagttcct ctttcccctt tttcgagagc gacagttcca
    92401 actactttgt cagggtcatt cttgtcgtag acaacaacag aaaccttatc agcacttggt
    92461 gaccaaaggg tcaaatcaac ttgttttcct tcttctttta ggtcagctcc cagtttgcca
    92521 tcatagctgt atgtctcatc tttcaggtgc cagcttgttt tggtagtgaa ttggtcggaa
    92581 ttgtagctaa cagtataagg gtgttttgtg tcagagaaat ctccgctgta ggtcactttc
    92641 ttaccagctt catcgattgc aacatcggta atagttacct tgtttcctag gtgattagtg
    92701 atgttggagt gtttgaggat atcttctttt ttagcaccga caagtgttga aaagctactt
    92761 tcaatgctag aagtgcctac gtgttgggct cctgtcatac ggatatcatg gacatagtat
    92821 ggatttgtgt aaatcgattc atcatcgtct tttaggaaaa tttggctatg atttttcaaa
    92881 tctgtgaact tataattttc tttacggatt ttcacgtcgt ctccttgttt gctctcatct
    92941 agtaataaaa atccaaattc tcttgcggct tcattaagag gaatgtcgat atagcggcca
    93001 tatttgcctg tagccgtaaa gtctgttccg tcaggccatt gagcgctact tggatttttc
    93061 acatctcccc agtaccagag agatttcttg tcatagttgc catctgtgcg gtagtagttg
    93121 acgcgaacag ttcctgcagg ctgtggctcg taagagaaaa ccttgtaatc ttggtctaac
    93181 caagcttcgt tcatttttgg aactagtttt tctacagatt tatcgccggt tagatttttt
    93241 ccagctgtat tgttgatgag gaagctaatt ttcttggctt gttctccctt taatttgaca
    93301 tctaggtaat agccgtagtc atctttcttg gcatccttga aggacaaagc tccgtttggc
    93361 cagttttcag atggtttttc aacatcgtcc caagtccata gtccttgagc atccttgttt
    93421 tcttcaggaa gttttttgac atggatacgg aagtagttat cttcgatggg ctcttctgcc
    93481 ttagtttcag ttgttactgg actagtagaa gtagttggct ctgttgcagg tttttcttct
    93541 gttttctcta gggaagcgtt tgcatttcta ggtgaagaaa tatcactttc gttcttacca
    93601 gagccagctg ctgtatcagt aagaggttgg gcaagggtgg ttgtatttct gttgttgggt
    93661 tcgttagtgg ttggtgtact ttcgtcggat gagatagttg gtgtagccat ggcaagcaag
    93721 acaaggcttg cgccgataag gacagaacca gttccatttt tgagggaacg gatgctgtag
    93781 accatttttt tctcagtgtg agatggtgtt tttctcataa tgattctcca atcaataaat
    93841 ttctatatca gtatagcatg tagtaaaaca atatgcaagc gttttctttg atttgtgaaa
    93901 aaattcttac ttttgagaag ttttctgtac tattttatat atcagtataa atgacggaga
    93961 taaaaatgtc acataagcca agccgtatta ttaggaagat gatgtgttcc cagctatttt
    94021 tattcagaaa ttgatctcta acattaccaa taaaaaagaa aaatatcttg acaagcaagg
    94081 gaaaattttg ttacaataat agacggtact ttttactttt ggtctctcaa gagtgtacag
    94141 ggacgtgctg acaaatgttg caaaagtaca cacagatgat atctgtcacc aagtgtatca
    94201 tcaccaaaaa taaaaaaaca caggagaatg tagatgccta caattaacca attggttcgc
    94261 aaaccgcgta aatcaaaagt agaaaaatct aaatcaccag ctttgaacgt tggttacaat
    94321 agtcataaaa aagttcaaac aaacgtttct tcaccacaaa aacgtggtgt tgcaactcgt
    94381 gttggaacaa tgacacctaa aaaacctaac tcagcccttc gtaaattcgc tcgtgtacgt
    94441 ttgagcaacc ttatcgaagt tactgcctac atcccaggta tcggacacaa cttgcaagag
    94501 cacagcgtgg tgcttcttcg cggtggacgt gtaaaagacc ttccaggggt acgttaccat
    94561 atcgtccgtg gtgcacttga tactgcaggt gttaacgatc gtaaacaagg ccgttctaaa
    94621 tacggtacta aacgtccaaa agcataagga aaggggataa agagaaatga gtcgtaaaaa
    94681 tagagctcca aaacgtgacg tattgccaga tccgctatac aattcacaac tagttactcg
    94741 tcttatcaac cgcgttatgc ttgatggtaa acgtggtact gctgcttcaa tcgtttacgg
    94801 tgcttttgag caaatcaaag aagctactgg caacgatgca cttgaagtat ttgaaacagc
    94861 tatggaaaac atcatgcctg tacttgaagt acgtgcacgt cgtgttggtg gttctaacta
    94921 ccaagtccca gttgaagttc gtccagaacg tcgtacaaca cttggacttc gttggttggt
    94981 aacaatcgct cgtcttcgtg gtgaacacac aatgcaagac cgtcttgcaa aagaaatctt
    95041 ggatgctgct aacaacactg gtgcagcagt taagaaacgt gaagatactc accgtatggc
    95101 tgaagctaac cgtgcattcg cacacttccg ttggtaagat aggatgcgaa agcgttaaga
    95161 aagtcccaga gaaaataggg aatcgaagca ggttgcggtt gcaaccaatg agattcatct
    95221 ttttctccag acttttagct tgagctcaac taaatcatga tgctaggcac ggaaggatgc
    95281 aaggtgaaaa taggaaactg acgcagtatt caacgaatac aaggagtttt atctttttca
    95341 cgcagcatcc cgttccagct cacatcggct aactaacttt agcctgggtt caaattagct
    95401 aaatcgatta gtattagcta taactcagct taccatctcg taagttgaaa ccaacaatag
    95461 catgaaaaca ttgagaacgg gtaggtcctg cctatccgtt tttattaaaa tcgtgttata
    95521 atagaataga aatcaaaaat aaataggaga aacaaacctc atggcacgcg aattttcact
    95581 tgaaaaaact cgtaatatcg gtatcatggc tcacgtcgat gccggtaaaa caacaactac
    95641 tgagcgtatt ctttactaca ctggtaaaat ccacaaaatc ggtgaaactc acgaaggtgc
    95701 gtcacaaatg gactggatgg agcaagagca agaacgtggt atcacgatca catctgctgc
    95761 gacaacagct caatggaaca accaccgcgt aaacatcatc gacacaccag gacacgtgga
    95821 cttcacaatc gaagtacaac gttctcttcg tgtattggat ggtgcggtta ccgttcttga
    95881 ctcacaatca ggtgttgaac ctcaaactga aacagtttgg cgtcaagcaa ctgagtacgg
    95941 agttccacgt atcgtatttg ccaacaaaat ggacaaaatc ggtgctgact tcctttactc
    96001 tgtaagcaca cttcacgatc gtcttcaagc aaatgcacac ccaatccaat tgccaatcgg
    96061 ttctgaagat gacttccgtg gtatcattga cttgatcaag atgaaagctg aaatctatac
    96121 taacgacctt ggtacggata tccttgaaga agacatccca gctgaatacc ttgaccaagc
    96181 tcaagaatac cgtgaaaaat tgattgaagc agttgctgaa actgacgaag aattgatgat
    96241 gaaatacctc gaaggtgaag aaatcactaa cgaagaattg aaagctggta tccgtaaagc
    96301 gactatcaac gttgaattct tcccagtatt gtgtggttca gccttcaaaa acaaaggtgt
    96361 tcaattgatg cttgatgcgg ttatcgacta ccttccaagt ccacttgaca tcccagcaat
    96421 caaaggtatt aacccagata cagacgctga agaaactcgt ccagcatctg acgaagagcc
    96481 atttgcagct cttgccttca agatcatgac tgacccattc gtaggtcgtt tgacattctt
    96541 ccgtgtttac tcaggtgttc ttcaatcagg ttcatacgta ttgaatactt ctaaaggtaa
    96601 acgtgaacgt atcggacgta tccttcaaat gcacgctaac agccgtcaag aaatcgacac
    96661 tgtttactca ggtgatatcg ctgctgccgt tggtttgaaa gatactacaa ctggtgactc
    96721 attgacagat gaaaaagcta aaatcatcct tgagtcaatc aacgttccag aaccagttat
    96781 ccaattgatg gttgagccaa aatctaaagc tgaccaagac aagatgggta tcgcccttca
    96841 aaaattggct gaagaagatc caacattccg cgttgaaaca aacgttgaaa ctggtgaaac
    96901 agttatctca ggtatgggtg aacttcacct tgacgtcctt gttgatcgta tgcgtcgtga
    96961 gttcaaagtt gaagcgaacg taggtgctcc tcaagtatct taccgtgaaa cattccgcgc
    97021 ttctactcaa gcacgtggat tcttcaaacg tcagtctggt ggtaaaggtc aattcggtga
    97081 tgtgtggatt gaatttactc caaacgaaga aggtaaagga ttcgaattcg aaaacgcaat
    97141 cgtcggtggt gtggttcctc gtgaatttat cccagcggtt gaaaaaggtt tggtagaatc
    97201 tatggctaac ggtgttcttg caggttaccc aatggttgac gttaaagcta agctttatga
    97261 tggttcatat cacgatgtcg actcatctga aactgccttc aagattgcgg cttcactttc
    97321 ccttaaagaa gctgctaaat cagcacaacc agctatcctt gaaccaatga tgcttgtaac
    97381 aatcactgtt ccagaagaaa accttggtga tgttatgggt cacgtaactg ctcgtcgtgg
    97441 acgtgtagat ggtatggaag cacacggtaa cagccaaatc gttcgtgctt acgttccact
    97501 tgctgaaatg ttcggttacg caacagttct tcgttctgca tctcaaggac gtggtacatt
    97561 catgatggta tttgaccact acgaagatgt acctaagtca gtacaagaag aaattattaa
    97621 gaaaaataaa ggtgaagact aatccgtcct cactctagaa ggaagtcact tagtggcttc
    97681 cttttgtctt tagaaaatac ctctaaatat ggtaaaatag tagaagaata atgtgaggaa
    97741 aatgaatgtc aaatagtttt gaaattttga tgaatcaatt ggggatgcct gctgaaatga
    97801 gacaggctcc tgctttagca caggccaata ttgagcgagt tgtggttcat aaaattagta
    97861 aggtatggga gtttcatttc gtattttcta atattttacc gattgaaatc tttttagaat
    97921 taaagaaagg tttgagcgaa gaattttcta agacaggcaa taaagctgtt tttgaaatta
    97981 aggctcggtc tcaagaattt tcaaatcagc tcttgcagtc ctactatagg gaggctttct
    98041 ctgaaggtcc atgtgctagt caaggtttta agtcccttta tcaaaatttg caagttcgtg
    98101 ctgagggtaa tcagctattt attgaaggat ctgaagcgat tgataaggaa cattttaaga
    98161 agaatcatct tcctaattta gccaaacaac ttgaaaagtt tggttttcca acttttaact
    98221 gtcaagttga gaagaatgat gtcctgaccc aagagcagga agaggccttt catgctgaaa
    98281 atgagcagat tgttcaagct gccaatgagg aagcgctccg tgctatggaa caactggagc
    98341 agatggcacc tcctccagcg gaagagaaac cagtctttga ttttcaagcg aaaaaagctg
    98401 cagctaaacc caagctggat aaggcggaga ttactcctat gatcgaagtg acgacagagg
    98461 aaaatcgtct ggtatttgaa ggggttgttt ttgatgtgga gcaaaaagtg actagaacag
    98521 gtcgtgtttt aatcaacttt aaaatgacgg actatacttc aagtttttct atgcaaaagt
    98581 gggttaaaaa cgaggaagag gcccagaagt ttgacctcat caagaagaat tcttggctcc
    98641 gagttcgagg gaatgtggag atgaataact tcacacgcga tttgactatg aacgtacagg
    98701 atctgcagga agttgttcac tatgagcgga aggatttgat gccagaaggt gagcgtcggg
    98761 ttgagtttca tgctcatact aacatgtcga ctatggatgc tttgccagag gtcgaagaga
    98821 ttgttgcaac agctgctaag tggggacaca aggcggttgc tatcacagac catgggaatg
    98881 tccagtcctt tccacatggc tataaggcgg ctaagaaagc gggaatccag ctgatctatg
    98941 ggatagaagc caatatcgtg gaggaccgtg tccctatcgt ctataacgaa gtggagatgg
    99001 acttatcaga agcaacctac gtggtctttg acgtggaaac gacgggactt tcagctatct
    99061 ataatgactt gattcaggtt gcggcctcta agatgtacaa ggggaatgtt attgctgaat
    99121 ttgatgaatt tatcaatcct gggcatccct tgtcagcttt tactacagag ttaactggaa
    99181 ttacagatga tcatgtcaaa aatgccaaac cactagaaca agttttgcaa gaattccaag
    99241 aattttgcaa ggatacggtc ctagttgccc acaatgctgc ctttgacgtt ggctttatga
    99301 atgctaatta tgagcgtcat ggtcttccaa agattagtca gccagttatt gatacgctgg
    99361 agtttgctag aaacctctat cctgagtata aacgccatgg tttggggcct ttgaccaagc
    99421 gttttggtgt ggccttggaa catcaccaca tggccaacta cgatgcggaa gcgactggtc
    99481 gtctgctttt catctttatc aaagaggtag cagaaaaaca tggtgtgacc gatttagcta
    99541 gactcaacat tgatctaatc agtccagatt cttacaaaaa agctcggatc aagcatgcga
    99601 ccatctatgt caagaatcag gtaggtctaa aaaatatctt taagctggtt tccttgtcta
    99661 ataccaagta ttttgaagga gtgccacgga ttccgagaac ggttctagat gcccatcgag
    99721 agggcttgat tttaggttca gcctgttcag agggtgaagt ttttgacgtg gtcgtttctc
    99781 aaggtgtgga tgcggcggtt gaggtggcca agtattatga ctttatcgag gtcatgccac
    99841 cggctatcta tgcgcccttg attgctaaag agcaggtcaa ggatatggag gaactccaga
    99901 ccattatcaa gagtttgata gaggttggag accgccttgg caagcctgtt ttggctacgg
    99961 gaaatgttca ctatatcgaa ccggaagaag agatttatcg tgaaattatc gtccgtagtt
   100021 tgggacaggg tgcgatgatt aaccgaacta tcggtcatgg tgaacatgcc caaccagcac
   100081 cacttccaaa ggctcatttt cgaacgacta atgagatgtt ggatgaattt gcctttttgg
   100141 gagaggaact ggctcgtaaa ctggttattg aaaacaccaa tgccttggca gaaatatttg
   100201 aacccgttga agtcgttaag ggtgacttgt atacgccttt catcgacaag gctgaagaaa
   100261 cagttgctga gttgacctat aagaaagctt ttgagattta tggaaatccg ctgccagata
   100321 ttgttgattt gcggattgaa aaagaattaa catccatact ggggaatgga tttgctgtga
   100381 tttatctggc atcgcagatg ctggtgcaac gttctaatga acggggttat ttggttggtt
   100441 ctcgtgggtc tgtcggatct agtttcgttg cgaccatgat tggaattacg gaggtcaatc
   100501 ctctctctcc tcactatgtc tgtggtcagt gtcagtacag tgagtttatc acagatggtt
   100561 cgtacggttc aggatttgat atgccccata aggactgtcc aaactgtggt cacaaactca
   100621 gtaaaaacgg acaggatatt ccgtttgaga ccttccttgg ttttgatggg gataaggttc
   100681 ctgatattga cttgaacttc tcgggagaag atcagcctag cgcccacttg gatgtgcgtg
   100741 atatctttgg tgaagaatat gccttccgtg cgggaacagt tggtacggta gctgccaaga
   100801 ctgcctatgg atttgtcaag ggttacgagc gagattatgg caagttttat cgtgatgcag
   100861 aagtagaacg cctcgctcaa ggagcggcgg gtgtcaagcg gacaacaggc caacacccgg
   100921 ggggaatcgt tgttattccg aactacatgg atgtctacga ttttacgcct gtccagtatc
   100981 cagcagatga tgtcacggct gaatggcaga ccactcactt taacttccac gatatcgatg
   101041 agaacgtcct caaactcgat gtactgggac atgatgatcc gaccatgatt cgaaaacttc
   101101 aggatttgtc tggtattgac cctaataaaa ttcctatgga tgacgaaggc gtgatggcac
   101161 tcttttctgg gactgatgtg ctaggggtaa cacctgaaca aattggaacg cctacgggta
   101221 tgttggggat tccagagttt ggaacaaatt tcgtacgtgg aatggtagac gaaacccatc
   101281 cgacaacctt tgcggaattg cttcagctgt ctggtctgtc ccacggtact gatgtttggt
   101341 tggggaatgc tcaggatctg attaagcaag gaatagcgga cctatcgact gttatcggtt
   101401 gtcgggacga catcatggtt tacctcatgc atgcgggtct ggaacctaag atggccttta
   101461 ccattatgga acgggtacgt aagggtttgt ggctaaagat ttcagaagag gagagaaatg
   101521 gctatatcga agcaatgaag gctaataagg tgccagagtg gtatatcgaa tcctgtggga
   101581 aaattaagta catgttccct aaggcccatg cggcagccta cgttatgatg gccttgcgtg
   101641 tagcttactt caaggttcac catcctattt attactactg tgcttacttc tccattcgtg
   101701 ctaaggcttt tgatatcaag accatgggtg cgggcttgga ggtcatcaag cgcagaatgg
   101761 aagaaatctc tgaaaaacgg aagaacaatg aagcctctaa tgtggaaatc gatctctata
   101821 caactcttga gattgtcaat gagatgtggg aacgaggttt caagtttggt aaattagatc
   101881 tctaccgtag tcaggcgaca gagttcctca tcgacgggga tacccttatc ccaccatttg
   101941 tagcaatgga tggtctggga gagaacgttg ccaagcaact ggtgcgggcg cgtgaagagg
   102001 gagaattcct ctctaaaaca gaactacgca agcgtggtgg actctcatca accttggttg
   102061 aaaagatgga tgagatgggt attcttggaa atatgccaga ggataaccag ttgagtttgt
   102121 ttgatgagtt gttttaaaaa attgcttaat aatctattaa aagaggctaa cgtatatcca
   102181 atagatttac attagctttc ttttttgtta aaatagtcta tggaaagagg gtgagagtat
   102241 gtcaaagatg agtataagca tccgtctgga tagtgaggtt aaggagcagg cccaacaggt
   102301 gtttagtaat ctgggaatgg atatgacaac agctattaat attttccttc gtcaggcaat
   102361 tcaatatcag ggattacctt ttgatgttag actagacgaa aatcggaagt tgctccaagc
   102421 gttaacggat ttagaccaaa atcgtaatat gagccagtct tttgaatcag tctcagattt
   102481 gatggaggac ttacgtgctt aagattcgtt atcataaaca gtttaaaaaa gattttaagt
   102541 tggctatgaa gcgtggtttg aaggcagaat tattagaaga agttttgaat tttctggttc
   102601 aagaaaaaga acatcctgcc agatatcgtg atcattcatt gacggcatcc aagcattttc
   102661 aaggagttcg tgaatgccat acccagccag attggctttt ggtttataaa gtagacaagt
   102721 cggaattgat tttaaatttg ctgaggacag gcagtcacag tgatttattt taatctattt
   102781 taagggggtt ctcatgaaac taagaatatt tgcggaagat aagccggcta agaaggtatt
   102841 tgaatatcaa ttagaacttg ctgatcgtac aattcttcta tcgacagcac tcttgtcagg
   102901 tgctattgct ttagcaggaa tcttttctgc tttgaaagaa aaataaaaat agaaaagaga
   102961 aaacagaatg gttttaccaa attttaaaga aaatctagaa aaatatgcga aattgttggt
   103021 tgcgaacgga attaacgtgc aacctggtca cactttggct ctctctattg atgtggagca
   103081 acgtgaattg gcacatctaa tcgtgaaaga agcttatgcc ttgggtgcgc atgaggtcat
   103141 cgttcagtgg acagatgatg tgattaaccg tgagaaattc ctccatgccc cgatggagcg
   103201 tttggacaat gtgccagaat acaagattgc tgagatgaac tatcttttgg agaacaaggc
   103261 tagccgtctt ggggttcgtt catctgatcc aggtgccttg aacggagtgg acgctgacaa
   103321 gctttcagct tctgctaaag ctatgggact tgccatgaag cctatgcgta tcgcaactca
   103381 atctaacaag gttagctgga ctgtagcagc cgctgctgga cttgagtggg ctaagaaagt
   103441 cttcccaaat gctgcgagcg acgaagaagc agttgatttc ctttgggatc aaatcttcaa
   103501 aacttgtcgt gtctacgaag cagatcctgt taaggcttgg gaggaacatg cagccattct
   103561 caagagcaag gccgatatgc ttaataagga gcaattttca gcccttcact acacagcgcc
   103621 aggaacagat ttaacacttg gtttgccaaa gaaccacgtt tgggaatcag ctggtgctgt
   103681 caatgcacag ggcgaagaat tcttgccaaa tatgccgaca gaagaggtct tcacagcgcc
   103741 tgacttccgt cgtgcagatg gttatgtcac ttctacaaaa ccgcttagct acaacggaaa
   103801 tatcattgaa ggcattaagg tgacctttaa ggatggacaa atcgtagata tcactgctga
   103861 gaagggtgat caggttatga aagaccttgt ctttgaaaat gcgggtgcgc gtgccttggg
   103921 tgaatgtgcc ttggtaccag atccaagtcc aatttctcag tcaggcatta ccttttttaa
   103981 cacccttttc gatgaaaatg cgtcaaacca cttggctatc ggtgcagcct atgcgactag
   104041 cgttgttgat ggagcggaga tgagcgaaga ggagcttgaa gctgcagggc ttaaccgttc
   104101 agatgttcac gtagacttta tgattggttc taaccaaatg gatatcgatg gtattcgtga
   104161 ggatggaacg cgggtacctc ttttccgtaa tgggaattgg gcaaattaag gagataatat
   104221 gttaggaagt atgttcgttg gtctcctagt gggattttta gcaggtgcta tgaccaatcg
   104281 tggagagcga atgggatgtt ttggaaaaat gtttctcggt tggatcggag cctttctagg
   104341 tcacttgctc tttggaactt gggggccagt tttatcagga acagctatta tcccagcgat
   104401 tttaggagcc atgattgttt tagctatttt ttggagacga ggaagttaat ttcctaaatc
   104461 tgatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaggttg ctcaaa
//
LOCUS       DBEJJV010000002        89199 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.002, whole genome shotgun sequence.
ACCESSION   DBEJJV010000002 DBEJJV010000000
VERSION     DBEJJV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 89199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89199
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.002"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(21..956)
                     /gene="birA"
                     /locus_tag="ACL3GT_000113"
     CDS             complement(21..956)
                     /gene="birA"
                     /locus_tag="ACL3GT_000113"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HGR0515851.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLQQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(953..1813)
                     /locus_tag="ACL3GT_000114"
     CDS             complement(953..1813)
                     /locus_tag="ACL3GT_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0515852.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRAGQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            1921..4083
                     /locus_tag="ACL3GT_000115"
     CDS             1921..4083
                     /locus_tag="ACL3GT_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HGR0515853.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4175..5434
                     /locus_tag="ACL3GT_000116"
     CDS             4175..5434
                     /locus_tag="ACL3GT_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0515854.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNAYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5448..6314
                     /locus_tag="ACL3GT_000117"
     CDS             5448..6314
                     /locus_tag="ACL3GT_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0515855.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            6328..7161
                     /locus_tag="ACL3GT_000118"
     CDS             6328..7161
                     /locus_tag="ACL3GT_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0515856.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     VFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7168..7335
                     /locus_tag="ACL3GT_000119"
     CDS             7168..7335
                     /locus_tag="ACL3GT_000119"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515857.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKVKLTWFEEI
                     FEEYKKSSWNL"
     gene            7519..8961
                     /gene="gtfA"
                     /locus_tag="ACL3GT_000120"
     CDS             7519..8961
                     /gene="gtfA"
                     /locus_tag="ACL3GT_000120"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004645 - 1,4-alpha-oligoglucan
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HGR0515858.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9099..10292
                     /locus_tag="ACL3GT_000121"
     CDS             9099..10292
                     /locus_tag="ACL3GT_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGR0515859.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVFCLYIIS
                     LIFTGDMKSILQKMGEHSMLLLFLGYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            10978..12957
                     /locus_tag="ACL3GT_000122"
     CDS             10978..12957
                     /locus_tag="ACL3GT_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0515860.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKTSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KAVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13024..14520
                     /locus_tag="ACL3GT_000123"
     CDS             13024..14520
                     /locus_tag="ACL3GT_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515861.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSISLPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14520..15446
                     /gene="oppC"
                     /locus_tag="ACL3GT_000124"
     CDS             14520..15446
                     /gene="oppC"
                     /locus_tag="ACL3GT_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HGR0515862.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15455..16522
                     /locus_tag="ACL3GT_000125"
     CDS             15455..16522
                     /locus_tag="ACL3GT_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515863.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSKTHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16533..17459
                     /locus_tag="ACL3GT_000126"
     CDS             16533..17459
                     /locus_tag="ACL3GT_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0515864.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            17525..17656
                     /locus_tag="ACL3GT_000127"
     CDS             17525..17656
                     /locus_tag="ACL3GT_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515865.1"
                     /translation="MKNFESFLKEFLKNFKNYEMLLTGDEKGGRTGSIKKESRKRNE"
     gene            17949..18886
                     /locus_tag="ACL3GT_000128"
                     /pseudo
     CDS             17949..18886
                     /locus_tag="ACL3GT_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            18898..19791
                     /locus_tag="ACL3GT_000129"
     CDS             18898..19791
                     /locus_tag="ACL3GT_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515866.1"
                     /translation="MNFVLSSLSEGLLWSIVAIGVYLTFRILDIADMTAEGAFPLGAA
                     VVVSQIQAGANPWLATLLALLTGMVAGLVSGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGTVFSLSLACFLLVCLVLTLLMKTEIGLVL
                     RSTGDNIPMSEANGVNVDTMKIVGYMISNGLIALCGSLFAQNDGFSDVTSGTGTIVVG
                     LSSVIIAEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYEIPNLDQNLVRLFNAILLAL
                     VLFAPELQKRLKIRGLKLRNE"
     gene            19804..20607
                     /locus_tag="ACL3GT_000130"
     CDS             19804..20607
                     /locus_tag="ACL3GT_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515867.1"
                     /translation="MTSLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMTDLMKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(20640..21350)
                     /gene="treR"
                     /locus_tag="ACL3GT_000131"
     CDS             complement(20640..21350)
                     /gene="treR"
                     /locus_tag="ACL3GT_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HGR0515868.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIREQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21535..23502
                     /gene="treP"
                     /locus_tag="ACL3GT_000132"
     CDS             21535..23502
                     /gene="treP"
                     /locus_tag="ACL3GT_000132"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HGR0515869.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKGLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            23680..25305
                     /gene="treC"
                     /locus_tag="ACL3GT_000133"
     CDS             23680..25305
                     /gene="treC"
                     /locus_tag="ACL3GT_000133"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HGR0515870.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25561..25809
                     /locus_tag="ACL3GT_000134"
     CDS             25561..25809
                     /locus_tag="ACL3GT_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HGR0515871.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26016..26810
                     /gene="racE"
                     /locus_tag="ACL3GT_000135"
     CDS             26016..26810
                     /gene="racE"
                     /locus_tag="ACL3GT_000135"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HGR0515872.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            26807..27778
                     /locus_tag="ACL3GT_000136"
     CDS             26807..27778
                     /locus_tag="ACL3GT_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009143 - nucleoside triphosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HGR0515873.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            27754..28275
                     /locus_tag="ACL3GT_000137"
     CDS             27754..28275
                     /locus_tag="ACL3GT_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HGR0515874.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28272..28733
                     /gene="cbpB"
                     /locus_tag="ACL3GT_000138"
     CDS             28272..28733
                     /gene="cbpB"
                     /locus_tag="ACL3GT_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HGR0515875.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            28730..29464
                     /gene="xerD"
                     /locus_tag="ACL3GT_000139"
     CDS             28730..29464
                     /gene="xerD"
                     /locus_tag="ACL3GT_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HGR0515876.1"
                     /translation="MRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETSLK
                     IYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEILYL
                     DSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVTIP
                     TALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFILRQ
                     IENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29464..30192
                     /locus_tag="ACL3GT_000140"
     CDS             29464..30192
                     /locus_tag="ACL3GT_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HGR0515877.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30211..30780
                     /gene="scpB"
                     /locus_tag="ACL3GT_000141"
     CDS             30211..30780
                     /gene="scpB"
                     /locus_tag="ACL3GT_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HGR0515878.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            30767..31489
                     /locus_tag="ACL3GT_000142"
     CDS             30767..31489
                     /locus_tag="ACL3GT_000142"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0515879.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31489..31731
                     /gene="yidD"
                     /locus_tag="ACL3GT_000143"
     CDS             31489..31731
                     /gene="yidD"
                     /locus_tag="ACL3GT_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HGR0515880.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(31956..32921)
                     /locus_tag="ACL3GT_000144"
     CDS             complement(31956..32921)
                     /locus_tag="ACL3GT_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0515881.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLAEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33017..33769)
                     /locus_tag="ACL3GT_000145"
     CDS             complement(33017..33769)
                     /locus_tag="ACL3GT_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515882.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINIASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(33766..34722)
                     /locus_tag="ACL3GT_000146"
     CDS             complement(33766..34722)
                     /locus_tag="ACL3GT_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HGR0515883.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(34712..35671)
                     /locus_tag="ACL3GT_000147"
     CDS             complement(34712..35671)
                     /locus_tag="ACL3GT_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515884.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(35968..36078)
                     /locus_tag="ACL3GT_000148"
     CDS             complement(35968..36078)
                     /locus_tag="ACL3GT_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HGR0515885.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            complement(36094..36795)
                     /gene="galE"
                     /locus_tag="ACL3GT_000149"
     CDS             complement(36094..36795)
                     /gene="galE"
                     /locus_tag="ACL3GT_000149"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0515886.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37196..38260
                     /gene="pepA"
                     /locus_tag="ACL3GT_000150"
     CDS             37196..38260
                     /gene="pepA"
                     /locus_tag="ACL3GT_000150"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HGR0515887.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38282..38578
                     /locus_tag="ACL3GT_000151"
     CDS             38282..38578
                     /locus_tag="ACL3GT_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0515888.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSSLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            39260..39703
                     /locus_tag="ACL3GT_000152"
     CDS             39260..39703
                     /locus_tag="ACL3GT_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0515889.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKENEV"
     gene            39707..40471
                     /locus_tag="ACL3GT_000153"
     CDS             39707..40471
                     /locus_tag="ACL3GT_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HGR0515890.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTETFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVIPKVEDLTNRGKF"
     gene            40486..41214
                     /locus_tag="ACL3GT_000154"
     CDS             40486..41214
                     /locus_tag="ACL3GT_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0515891.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIENGEFMVLVGPSGSGKTTMI
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLTTGYVLQAIALFPNLTVEENIALIPEM
                     KGWTKEEIAQKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41207..42727
                     /locus_tag="ACL3GT_000155"
     CDS             41207..42727
                     /locus_tag="ACL3GT_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HGR0515892.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43072..43878
                     /gene="pnuC"
                     /locus_tag="ACL3GT_000156"
     CDS             43072..43878
                     /gene="pnuC"
                     /locus_tag="ACL3GT_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HGR0515893.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(44044..44580)
                     /gene="sczA"
                     /locus_tag="ACL3GT_000157"
     CDS             complement(44044..44580)
                     /gene="sczA"
                     /locus_tag="ACL3GT_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator SczA"
                     /protein_id="HGR0515894.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            44713..45603
                     /gene="czcD"
                     /locus_tag="ACL3GT_000158"
     CDS             44713..45603
                     /gene="czcD"
                     /locus_tag="ACL3GT_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter
                     CzcD"
                     /protein_id="HGR0515895.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            45847..46200
                     /gene="nmlR"
                     /locus_tag="ACL3GT_000159"
     CDS             45847..46200
                     /gene="nmlR"
                     /locus_tag="ACL3GT_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="stress response transcriptional regulator NmlR"
                     /protein_id="HGR0515896.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            46201..47238
                     /locus_tag="ACL3GT_000160"
     CDS             46201..47238
                     /locus_tag="ACL3GT_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HGR0515897.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIIIE"
     gene            complement(47285..48292)
                     /gene="galR"
                     /locus_tag="ACL3GT_000161"
     CDS             complement(47285..48292)
                     /gene="galR"
                     /locus_tag="ACL3GT_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HGR0515898.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIEDKRLENFRNYSQAKGIYHDELIFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGINLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            48457..49635
                     /locus_tag="ACL3GT_000162"
     CDS             48457..49635
                     /locus_tag="ACL3GT_000162"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HGR0515899.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLDRLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            49654..51135
                     /locus_tag="ACL3GT_000163"
     CDS             49654..51135
                     /locus_tag="ACL3GT_000163"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0515900.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLEMIEDSQTAREILGTELMDLVTPYPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            51205..51609
                     /locus_tag="ACL3GT_000164"
     CDS             51205..51609
                     /locus_tag="ACL3GT_000164"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HGR0515901.1"
                     /translation="MKDFHFDAISAFESYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            51790..52554
                     /locus_tag="ACL3GT_000165"
     CDS             51790..52554
                     /locus_tag="ACL3GT_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnI"
                     /protein_id="HGR0515902.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            52551..53012
                     /locus_tag="ACL3GT_000166"
     CDS             52551..53012
                     /locus_tag="ACL3GT_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DpnD/PcfM family protein"
                     /protein_id="HGR0515903.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(53063..54325)
                     /locus_tag="ACL3GT_000167"
     CDS             complement(53063..54325)
                     /locus_tag="ACL3GT_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HGR0515904.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGNGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(54325..54906)
                     /locus_tag="ACL3GT_000168"
     CDS             complement(54325..54906)
                     /locus_tag="ACL3GT_000168"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HGR0515905.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(55306..55401)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(55784..56023)
                     /locus_tag="ACL3GT_000169"
     CDS             complement(55784..56023)
                     /locus_tag="ACL3GT_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HGR0515906.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     gene            complement(56071..56166)
                     /locus_tag="ACL3GT_000170"
                     /pseudo
     CDS             complement(56071..56166)
                     /locus_tag="ACL3GT_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
     gene            complement(56178..57005)
                     /locus_tag="ACL3GT_000171"
     CDS             complement(56178..57005)
                     /locus_tag="ACL3GT_000171"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HGR0515907.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            57139..57595
                     /locus_tag="ACL3GT_000172"
                     /pseudo
     CDS             57139..57595
                     /locus_tag="ACL3GT_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            57592..58122
                     /locus_tag="ACL3GT_000173"
     CDS             57592..58122
                     /locus_tag="ACL3GT_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HGR0515908.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            58250..59995
                     /locus_tag="ACL3GT_000174"
     CDS             58250..59995
                     /locus_tag="ACL3GT_000174"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515909.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLVVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            59985..61736
                     /locus_tag="ACL3GT_000175"
     CDS             59985..61736
                     /locus_tag="ACL3GT_000175"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515910.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            61909..62601
                     /locus_tag="ACL3GT_000176"
     CDS             61909..62601
                     /locus_tag="ACL3GT_000176"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0515911.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            62644..63870
                     /locus_tag="ACL3GT_000177"
     CDS             62644..63870
                     /locus_tag="ACL3GT_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HGR0515912.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            64491..64721
                     /locus_tag="ACL3GT_000178"
     CDS             64491..64721
                     /locus_tag="ACL3GT_000178"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515913.1"
                     /translation="MSDIQVNIPGECLYDKVFVLSFIIYNISTNLNIVNGIFYIQAKK
                     DSITFEWKAKEQTRKLAIDSSKPCFEVVDIVK"
     gene            65001..67160
                     /gene="pfbA"
                     /locus_tag="ACL3GT_000179"
     CDS             65001..67160
                     /gene="pfbA"
                     /locus_tag="ACL3GT_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HGR0515914.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            67144..67440
                     /locus_tag="ACL3GT_000180"
     CDS             67144..67440
                     /locus_tag="ACL3GT_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515915.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
     gene            67612..67995
                     /locus_tag="ACL3GT_000181"
     CDS             67612..67995
                     /locus_tag="ACL3GT_000181"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515916.1"
                     /translation="MLVNEMEITDHRVDNLFEKGKNEIKDPIGTNSVLNKKIILQKIR
                     KLSNQPSGYWIGSLDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELIK
                     MRFNSSAIDPIYGKKDDASIVVIDV"
     gene            68053..68694
                     /locus_tag="ACL3GT_000182"
     CDS             68053..68694
                     /locus_tag="ACL3GT_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HGR0515917.1"
                     /translation="MLRLYLENEIIELSNNLETIWVSVLDKYEKLFEYLSNEERIELI
                     KEDLIINESVLNVDKKGYELICLQHPVSYDLRRIISVIKISTDIERIGDRIVEILKNL
                     QIIQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGCLDMVVIQKQNEIEELST
                     NIEKKIMNYIFEDDGNVSEVIGALDIIHHLDKIAHTTQSIYKWIMYRKYGNIN"
     gene            68707..70182
                     /gene="galT"
                     /locus_tag="ACL3GT_000183"
     CDS             68707..70182
                     /gene="galT"
                     /locus_tag="ACL3GT_000183"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HGR0515918.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGTDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYLYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFRFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            70195..71175
                     /gene="galE"
                     /locus_tag="ACL3GT_000184"
     CDS             70195..71175
                     /gene="galE"
                     /locus_tag="ACL3GT_000184"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0515919.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSILVLDRI
                     EAITGIRPVFYELDVCDKPALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGLPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWN"
     gene            71385..72044
                     /locus_tag="ACL3GT_000185"
     CDS             71385..72044
                     /locus_tag="ACL3GT_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HGR0515920.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            72069..73136
                     /locus_tag="ACL3GT_000186"
     CDS             72069..73136
                     /locus_tag="ACL3GT_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0515921.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELASKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWGVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            73239..74249
                     /locus_tag="ACL3GT_000187"
     CDS             73239..74249
                     /locus_tag="ACL3GT_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515922.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            74261..75952
                     /locus_tag="ACL3GT_000188"
     CDS             74261..75952
                     /locus_tag="ACL3GT_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0515923.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            75955..76665
                     /locus_tag="ACL3GT_000189"
     CDS             75955..76665
                     /locus_tag="ACL3GT_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HGR0515924.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            76761..77129
                     /locus_tag="ACL3GT_000190"
     CDS             76761..77129
                     /locus_tag="ACL3GT_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515925.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            77237..78238
                     /locus_tag="ACL3GT_000191"
     CDS             77237..78238
                     /locus_tag="ACL3GT_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0515926.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     misc_binding    78450..78679
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            78845..79096
                     /locus_tag="ACL3GT_000192"
     CDS             78845..79096
                     /locus_tag="ACL3GT_000192"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515927.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDRTDEVSSKYCFEVVDRTDEVS
                     SKHCFEVADRTDEVSNHTYGKATLTRFEEIFEEYKGVSK"
     gene            79469..80830
                     /gene="trpE"
                     /locus_tag="ACL3GT_000193"
     CDS             79469..80830
                     /gene="trpE"
                     /locus_tag="ACL3GT_000193"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HGR0515928.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNSFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGVTDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            80827..81393
                     /locus_tag="ACL3GT_000194"
     CDS             80827..81393
                     /locus_tag="ACL3GT_000194"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004049 - anthranilate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HGR0515929.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            81404..82408
                     /gene="trpD"
                     /locus_tag="ACL3GT_000195"
     CDS             81404..82408
                     /gene="trpD"
                     /locus_tag="ACL3GT_000195"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004048 - anthranilate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HGR0515930.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDVRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            82405..83172
                     /gene="trpC"
                     /locus_tag="ACL3GT_000196"
     CDS             82405..83172
                     /gene="trpC"
                     /locus_tag="ACL3GT_000196"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004425 - indole-3-glycerol-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006568 - tryptophan metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HGR0515931.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLNYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            83159..83758
                     /locus_tag="ACL3GT_000197"
     CDS             83159..83758
                     /locus_tag="ACL3GT_000197"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HGR0515932.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            83736..84959
                     /gene="trpB"
                     /locus_tag="ACL3GT_000198"
     CDS             83736..84959
                     /gene="trpB"
                     /locus_tag="ACL3GT_000198"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HGR0515933.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            84952..85728
                     /gene="trpA"
                     /locus_tag="ACL3GT_000199"
     CDS             84952..85728
                     /gene="trpA"
                     /locus_tag="ACL3GT_000199"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004834 - tryptophan synthase activity
                     [Evidence IEA];
                     GO_process: GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HGR0515934.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(85700..85801)
                     /locus_tag="ACL3GT_000200"
                     /pseudo
     CDS             complement(85700..85801)
                     /locus_tag="ACL3GT_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            86030..86761
                     /locus_tag="ACL3GT_000201"
     CDS             86030..86761
                     /locus_tag="ACL3GT_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515935.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            86776..87927
                     /locus_tag="ACL3GT_000202"
     CDS             86776..87927
                     /locus_tag="ACL3GT_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0515936.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(87979..88638)
                     /locus_tag="ACL3GT_000203"
     CDS             complement(87979..88638)
                     /locus_tag="ACL3GT_000203"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HGR0515937.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWKLLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTCHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            88708..89154
                     /locus_tag="ACL3GT_000204"
     CDS             88708..89154
                     /locus_tag="ACL3GT_000204"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515938.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSILKLE"
BASE COUNT        26969 a        15806 c        19712 g        26712 t
ORIGIN      
        1 tatattataa ttgtgttatt ttacttccaa ctattgagag aaatttcgcc actatttagc
       61 cagatttctt ttccgttatc acattgaact aaaagttttc cattttctga gatgtcttta
      121 gcaagtccct tgtagtcttt ttgctgtagt gtgaaagtga cttcttttcc tagaatgaat
      181 gactgttttt tgtataggta taatagctct tctgctggtg tttcgaagaa agcacgccag
      241 atttctatga tcaattcatt ccttgttata ggagctgtag ctttaaataa gctggcagct
      301 ttttctttta attcctgagg gaagtcttta atagtgaaat tgatacctac tccaataatg
      361 atatctgtga ctaagccagt ttctacagag gtcattgctt cagtaaggat tcctccaatt
      421 ttatgattgt ttagatagat atcattgacc cattttatgt cgacatctat taaagttagg
      481 ttcttaatag ctttgtagac agctccagct acaagtagtg tgtaggatgg taatttgtca
      541 taggggagat ttggtttaag atggagtgtc atataaatac caccttgtgg tgagtagaag
      601 gaacgttgaa aacgtcctcg gcctgctgtt tgataggaag ctagatagag ggtatttgct
      661 tcatggccta aatcaattgc ttcttttgca tctagttgtg ttgattttgt ttcgggttta
      721 aagctgactt taattggaag attttcttct agaatctctg gaagaataag gtcaccattc
      781 attagtttat atcctctatt tttgatacta tcaatttcaa tgccttcttg ttctagtcgc
      841 ttgatagctt tccaaattga tgttcggctt agggatagtt tttctgcgat tttttctccg
      901 ctgatatagt cggtttcttt agataggatt tggtagacag cttggtagga tttcataatg
      961 ttgcctttct cactagttgg tattgagagt attcttttct tgtatgactt ggagtctgat
     1021 taaagtattg tttataagct ttcgaaaaat ggagtggatc tgaaaaacct accgagtatg
     1081 caattacctt gatggactct tgggtatttt cgagaagttg tccagctcgg tgcattcgaa
     1141 cgtagagtag gtattctttg ggtgataagg tattaaattc tttgaatacg cttgataagt
     1201 agcttctgtg aacggatagt tcttttgcta aatcttgaat tgtaagtgat tgaggatagt
     1261 ggctatcaat taatcgtttg cattcaagat agagttggtg ggttgatgaa atattctttt
     1321 ttttctgatt gggagcaata gttcccagat gaaacatcag ttcatgaagt tgtcccatga
     1381 tatggagttg agctaattca cttgattttg taatctgagc gaagcggaca atgtctgaga
     1441 tgagttttgc agtagtctgg gtatgacaag tttcagattg gatgagatag gattgatcag
     1501 aaatttggga aagagcaaaa taatcagggg ctttccctcc agtgattcct aaccagtagt
     1561 aggcccaagg ttctttacta tctgcttgat aaaaggttag ttcctctggt tttaatagaa
     1621 agaaatctcc ttcttttaaa tcaacaattt tacccttgta atgaaatttt ccttgtcctt
     1681 tagtaatgta atgtagaacg tatgtatcac gaatggctgg accaaaagag taattaggtg
     1741 tgcattcctc atatccataa aagcttaggg caaggtcgat tgttccagtc tggtattctg
     1801 aaaaaactaa catgtgctac ctcctaccta acattttacc atattcttga gacatttttc
     1861 tattttggaa agcgatttca ggtgataaaa tataatcaat aaagtgatga ggtgaagtaa
     1921 atgggagtta ggatagagaa taatctattt tatgttgaga gtaaaaatct aagtttgatt
     1981 attgaaaatc gaaatggcta cttacttttg aaacatttag gaaagactat taagaactat
     2041 aaaggttcca atagtgttta tgaacgagac catgcctttt caggaaatcc aacggctact
     2101 aatcgaacct ttagtttaga tactcaacgt caaatttttg gacaacatgg cttaggagat
     2161 tttaggaaac caaccataca ggttcagcat aatgtaactg aagtaacaga ctttcgattt
     2221 gtagaagcaa agattttaaa aggtcagaat ggtccacagg gcttaccttc tccacatagc
     2281 atggacgata cagagactct tgtcttaatg ttagaagatt ctaaggctca acttagtctg
     2341 actttgtatt atactacttt taataatgat gcgactattg ctagctacag taaattagat
     2401 aataatagta atcaggaagt tgtcatccat aaagattttt cttttatggc tgattttcca
     2461 gctgcagatt atgaaatagc aactctgcag ggtgcttatg ctcgtgaaaa gactgttaga
     2521 cgtcaacagg tagaacaagg aatcttttcg attagttcaa accgaggtgc ttctggtcat
     2581 gctcaaacac cagctcttct actatgcgaa caaggagtca cagaggatgc tgggaatgtg
     2641 tttgctattc aactaatgta tagtggcaac tttgaagctt ttgttcaaaa aaatcaattg
     2701 aatgaagttc gggtggctat tggcattaat ccagaaaact tttcttggaa gttagcccct
     2761 gaggaatact ttgaaacacc ggtagcttta gtgactcatt cagatcaggg attaactggt
     2821 attagtcatg aaagtcagaa ttttgtactg aagcacatta tgctaagtga attttctaaa
     2881 aaagaacgtc caattctaat caataactgg gaagctactt actttgactt tcagagagaa
     2941 aaactgttag agttagcaga tgaagctaag aaagttggca ttgaactttt tgtattagat
     3001 gatggttggt ttggcaatcg ttttgatgat aatcgtgctt taggtgattg ggttgttaat
     3061 gaggaaaaac tgggtggaag tctagaaagt ctgatttcag ctatccatga aagaggtttg
     3121 cagtttggac tttggttaga acccgaaatg atttctgtag atagtgattt gtatcgtcaa
     3181 catcctgact gggctattca ggttcctgat tatgagcata cttattctcg gaatcaatta
     3241 gtacttaatc ttgccaatcc tcaggtagta gaatacttga aaagtgtctt agatcaactc
     3301 ctatcttatc atgagattga ttacattaaa tgggatatga accgcaatat cactaagcta
     3361 gggaatggat taacttatct agagacacag atgcaatctc atcagtacat gctggggctt
     3421 tacgaactcg tttcttatct gacagagaag cacagccata ttctctttga gtcctgctct
     3481 ggtggtggtg gacgaaatga tcttggtatg atacgctatt tcccacaagt ctgggctagt
     3541 gataatactg atgccattgc acgtttacca attcaatacg gttcatccta tctctatcca
     3601 accatttcta tgggggctca tgtgtcagca gtaccgaatc atcagatggg acgaatgaca
     3661 ccattagaaa cacgtggcca tgtagcaatg atgggaaatt tgggctatga gcttgatttg
     3721 acaaatttat cagatgaaga gaaagctacg attgctaatc aggtgaactt gtataaagaa
     3781 ttacgaccag tagttcagtt aggacagcag tatagactaa ttaatcctga tactgcatcc
     3841 aatgaagcag ctgtacaatt taattacgga aatcaaacga ttgtaaccta cgttcgcgtt
     3901 ttatctgttg tagagaccat ggaaacaact ttaaaattaa aagatttgga tgaagaggga
     3961 ctatataaat tacaggaaaa tggcgaagtt tactcaggtg cagaactaat gtatgcgggc
     4021 ttaactgtta tcttatccca aggagatttt ttgagtagac agtatatttt tagaaaacta
     4081 tgatatgtac tgaccccaaa agttagattt attctgtcta acttttgggg tgcagttcaa
     4141 taagggtgta taaatttata aaggaggctt tctaatggaa tggtataaaa aaatcggact
     4201 tcttgcaact acaggtttag ctttgtttgg gctcggcgct tgctccaact atggtaaatc
     4261 tgcggatggc acagtgacca tcgagtattt caaccagaaa aaagaaatga ccaaaacctt
     4321 ggaagaaatc actcgtgatt ttgagaagga aaaccctaag atcaaggtca aagtcgtcaa
     4381 tgtaccaaat gctggtgaag tattgaagac acgcgttctc gcaggagatg tgcctgatgt
     4441 ggtcaatatt tacccacagt ccatcgaact gcaagaatgg gcaaaagcag gtgtttttga
     4501 agatttgagc aacaaagact acctgaaacg cgtgaaaaat gcctacgctg aaaaatatgc
     4561 tgtaaacgaa aaagtttata acgttccttt tacagctaat gcttatggaa tttactacaa
     4621 caaagataaa ttcgaagaac tgggcttgaa ggttcctgaa acctgggatg aatttgaaca
     4681 gttagtcaaa gatatcgttg ctaaaggaca aacaccattt ggaattgcag gtgcagatgc
     4741 ctggacactc aatggttaca atcaattagc ctttgcgaca gcaacaggtg gaggaaaaga
     4801 agcaaatcaa taccttcgtt attctcaacc aaatgccatt aaattgtcgg atccgattat
     4861 gaaagatgac atcaaggtca tggacatcct tcgcatcaat ggctctaagc aaaagaactg
     4921 ggaaggtgct ggctataccg atgttatcgg agccttcgca cgtggggatg tcctcatgac
     4981 accaaatggg tcttgggcga tcacagcgat taatgaacaa aaaccgaact ttaagattgg
     5041 gaccttcatg attccaggaa aagaaaaagg acaaagctta accgttggtg cgggagactt
     5101 ggcatggtct atctcagcca ccaccaaaca tccaaaagaa gccaatgcct ttgtggaata
     5161 tatgacccgt ccagaagtca tgcaaaaata ctacgatgtg gacggatctc caacagcgat
     5221 cgaaggggtc aaacaagcag gagaagattc accgcttgct ggtatgaccg aatatgcctt
     5281 tacggatcgt cacttggtct ggttgcaaca atactggacc agtgaagcag acttccatac
     5341 cttgaccatg aactatgtct tgaccggtga taaacaaggc atggtcaatg atttgaatgc
     5401 cttctttaac ccgatgaaag cggatgtgga ttaggagtag agagactatg aaaaaagtat
     5461 tacaaaaata ttgggcatgg gcttttgtgg tcatccccct cttgttacaa gcaattttct
     5521 tctatgtgcc gatgtttcaa ggagcctttt acagttttac caactggaca ggattgactt
     5581 acaactacaa atttgtcggc ttaaacaact ttaagctcct cttcatggat ccaaaattca
     5641 tgaatgcgat tggctttacc gcaatcatta cgattgccat ggtggttggt gagattgcac
     5701 tcgggatctt cattgcgcgt gtcttgaact ctaaaatcaa aggccaaacc ttcttccgtg
     5761 cttggttctt cttcccagct gttttatctg gtttgacagt ggctttgatc ttcaagcaag
     5821 tcttcaacta cggtcttcca gcgattggga atgcccttca tattgaattt ctccaaacca
     5881 gtcttttagg gactaagtgg ggagcaatct ttgcggctgt ctttgtcctt ctttggcaag
     5941 gggtggctat gcccatcatc atcttcctag ctggtttgca atctattcca actgagatta
     6001 cagaggcagc aaggattgat ggtgcgacta gcaagcaagt tttctggaac attgaattgc
     6061 cttacttgct accaagtgtc tctatggtct ttatcctagc cctaaaaggt gggctgactg
     6121 cctttgacca agtctttgcc atgaccggtg gtggtccaaa caatgccaca acctcacttg
     6181 ggctcttggt ttataactat gcctttaaaa acaaccaatt cggttatgcc aatgccattg
     6241 ccgtaatctt gttcctctta attgtagtga tttcgatcat ccaattgaga gtatctaaga
     6301 aatttgaaat ttaagaggag aagcatgatg aaacaagatg aaagaaaagc cctgattggc
     6361 aaatacattc tattgattct aggatcggtt ctgattttag tgccgctcct tgctaccctc
     6421 tttagttcct tcaaacccac taaggatatt gtagataatt tctttggctt tccaaccaac
     6481 ttcacatggg acaactttag ccgtctctta gctgatggga ttggaggcta ttattggaac
     6541 tctgtcgtca tcactgtctt gtctttactt gcagtaatga tctttatccc tatggcagcc
     6601 tactccatcg ctcgcaatat gagtaaaaga aaagtcttta ccatcatgta taccctctta
     6661 atcctcggaa tcttcgtacc tttccaagtc atcatgattc cgattacggt tatgatgagt
     6721 aaactcggtt tggctaatac ctttggtttg atcttgctct acttgaccta tgcgattcca
     6781 cagaccctct ttctctatgt tggctatatc aaaatctcga ttccagaaag tctggatgaa
     6841 gcagcagaga tcgatggggc taatcaattt acaacctatt tccgcatcat cttcccaatg
     6901 atgaaaccga tgcatgcgac aaccatgatc atcaatgccc tttggttctg gaatgacttc
     6961 atgttgccac tccttgtctt gaaccgggat tccaaaatgt ggactctgcc tttgttccaa
     7021 tacaactacg caggccaata tttcaacgac tacggaccaa gctttgcctc ttacgtggtc
     7081 ggcattatca gtatcaccat tgtctatctc ttcttccaac gccatatcat ttcaggaatg
     7141 agcaacgggg cagtgaagta atactcaatg aaaatcaaag agcaaactag gaagctagcc
     7201 gcaggttgct caaaacactg ttttgaggtt gtggatgaaa ctgacgaagt cagtaaccat
     7261 acctacggta aggtgaagct gacgtggttt gaagagattt tcgaagagta taagaagagc
     7321 tcatggaatc tatagtcttt gacacagagg aagagttcag cttgttgata attctatgta
     7381 gaaaacaaga aagtagtact ttgtttatca cagtctatat tagtacgagt ttgatgataa
     7441 atagagattt aaaatgaatt tgatttacga agccagatca tatgagactt ggcttcaatt
     7501 agaaaaagga gagtaatgat gccaattcaa aataaaacca tgttgattac ctattctgat
     7561 agccttggaa ataatcttaa agacttatat gataatttgg aagagcattt tggagatgct
     7621 attggaggag ttcacctttt accatttttc ccatcaacag gtgatcgtgg atttgcgcca
     7681 gttgactacg acgaagtgga ctcagctttt ggtgattggg aggatgttaa gcgtttaggt
     7741 gagaaatatt atcttatgtt tgattttatg attaatcata tttctcgtca atccaagtat
     7801 tataaggact atcaagaaaa acatgaagcc agtgaattta aagatctctt tttaaactgg
     7861 gataagtttt ggccagaaaa ccgtccgaca cagtctgatg tagatttaat ttacaagcgt
     7921 aaggatcgtg caccaaagca agagattgtg tttgaagatg gttcagtgga acatttgtgg
     7981 aatacctttg gtgaggagca gattgatctt gatgtgacca aagaagtaac tatggaattt
     8041 atccgtaaga ccattcagca cttggcaagt aatgggtgtg atttgattcg tctagatgcc
     8101 tttgcttatg cagtgaagaa attggatact aatgatttct ttgtggaacc agatatttgg
     8161 gatttattgg acaaagttcg agatatcgct gctgagtatg ggacagagct tttacctgag
     8221 attcatgaac actattcgat tcagtttaaa atagcagacc atgattacta tgtttatgat
     8281 tttgctcttc caatggtgac actttatact ctttacagtt ccagaacaga gcgtttggct
     8341 aagtggttaa agatgagccc gatgaagcaa tttacgacgc tagataccca tgatgggatt
     8401 ggagtagtag atgtcaagga tatcctgacc gatgaggaga ttgactatgc ttcaaatgaa
     8461 ctctataagg ttggagccaa tgtcaaacgt aagtactcta gtgccgagta taacaactta
     8521 gatatctacc aaatcaattc aacctactat tcagcgcttg gagatgatga tgtcaagtat
     8581 tttctcgctc gtctaattca agcttttgcc ccaggtattc ctcaggttta ctatgtgggt
     8641 ctattagcag gcaagaatga cttgaaatta ttagaagaaa ctaaagaagg tcgaaatatt
     8701 aatcgtcatt actatagcaa cgaggaaata gcaaaagaag tgcaacgacc tgttgtgaag
     8761 gcccttctca atctattttc tttccgtaac cgttcagaag cctttgatct agaagggact
     8821 actgagatag agacaccaac agctcacagc attgtaatca aacgtcaaaa taaagataag
     8881 tccgtaacag cagtagcaga aattgacttg caaaatcaga cttatcgggt aattgagaat
     8941 ggagttgaag taacattttg aagccttgat atggtggata aaatagggtt tttattttgg
     9001 aaaacgtttc ctttgttttc aaattgctaa aaaagtggta caatatagga tagcttacta
     9061 ttatctgaat cagctgattt ggagagaaag gattcatttt gaaatcaata ggctttattg
     9121 aaaagctgaa ggggttgtct agtaaagagc tgattttatt gggaattatc ctgagtatct
     9181 ttttaccctt ttatcttttt gtagttgtat tctgtttata tattatcagt ctgattttta
     9241 caggagacat gaaaagtatt cttcagaaaa tgggggagca ttcgatgctg cttctttttc
     9301 ttggctatag tactgttata tccattcttg cacaaaattg gatgggtctt gtggcttcag
     9361 taggaatgtt tctatttact attttctttt tgcactatca gtcgatttta tcccataaat
     9421 tctttcgatt gattttgcag ttcgtcttgt ttggtagtgt cttgtcagct gcttttgcca
     9481 gtttagaaca tttccaaatt gtgaagaaat ttaactatgc ttttctttcc cccaatatgc
     9541 aggtgtggca tcagaaccgg gcagaagtga ccttctttaa tcctaattat tatggaatta
     9601 tttgttgttt ctgtattatg attgctttct atctgtttac aacgaccaag ttgaattggt
     9661 tgaaagtatt ctgtgtgatt gcaggctttg ttaatctctt tggtttgaac tttactcaaa
     9721 atcgaactgc ctttcctgct attatcgctg gagcaattat ctatctcttt acgactatta
     9781 aaaactggaa ggccttttgg cttagtattg gggtcttcgc gattggtttg agtttcctct
     9841 tttctagtga tttgggagtt cgaatgggta ctttagactc ttctatggaa gaacgcattt
     9901 ctatctggga tgctgggatg gccttgttta agcaaaatcc tttttggggt gaagggccat
     9961 tgacctatat gcactcttat cctcggatac atgctcctta tcatgaacat gcccacagtc
    10021 tttatattga tacgattctg agttacggaa ttgtgggtac cattttatta gttctgtctt
    10081 ctgttgctcc tgttcgcttg atgatggata tgagtcagga gtcggggaaa cgtccgatta
    10141 tcggccttta tctatctttc cttacagtgg ttgctgtgca cggaattttt gacttggctc
    10201 tcttctggat tcagtcaggc tttattttct tgctagttat gtgcagtatt ccattggagc
    10261 atcgaatgtt ggtatcggac atgacggatt aagttttata agtttgaaat cttctacctt
    10321 gggtaggaga ttttttatac gatgggcatg tcgtgcatct gaggtgtaag tcctctgtag
    10381 ggatccacta ccggtgaata caatagcgct ccccaagcct gactatcgtg aggtagcgga
    10441 ttaaaatggt ctggggatag atcgttttaa gtctgacgca ggaaataaga attgtcagag
    10501 aaagcaatag tgaaatcgta ggctatgaat agaaacgtga tagcgaggag catatagtgg
    10561 ataaggtagc gagaaatttt aaagtataaa agatagtctt aatctatata tgtaaatcac
    10621 aaaagtaatt gaattcggaa taaggttggt gtgaaaagac atagtaaact gaatcttgaa
    10681 tactagaatg atacttctac aatattgtta taatttaatt tgaattccaa aatcacattg
    10741 ttccgtccgt atttcatttt actgtatgtc ttcctaaact ccaaagtttc tgcgtcaaat
    10801 ttcctatttt cactgtagtc tttgacactt cgaacgacaa tttgaatcat atattcaaaa
    10861 aaaaatgaaa aatttgtgcc aacaagccta aatattctga aaatttgttt gatttttaat
    10921 ggataatgtg atataatggt tgtcaatcta taattcacat aaacagagga gtagaaaatg
    10981 aaaaaaaatc gtgtatttgc tacagcaggt cttgttttat tagcagcagg tgtacttgca
    11041 gcatgcagtt cttcaaaaac atctgattca tcagccccta aagcttatgg ctatgtttat
    11101 acagcagacc cagaaacctt ggactacctg atttcaagta aaaatagtac aacagtagtg
    11161 acttcaaatg ggattgatgg tttattcact aacgataatt acggtaatct tgctcctgca
    11221 gttgcagagg attgggaagt ctctaaggat ggtttgacct acacttataa gattcgtaaa
    11281 ggggttaaat ggtttacctc tgatggagaa gaatatgcag aggtgacggc taaagatttc
    11341 gtgaacggtt taaaacacgc agcagataaa aaatcagaag ctatgtattt agctgaaaat
    11401 tcggttaaag gcttggcaga ttatctatca ggaacttcaa cagatttttc aacagttggt
    11461 gtcaaggcgg ttgatgatta tacgttacaa tacactttga accagcctga accgttctgg
    11521 aactctaagt tgacctattc tattttctgg cctctgaatg aagaattcga aacatcaaaa
    11581 ggaagcgatt ttgctaaacc aacagatccg acatccttgc tttataatgg tccattcttg
    11641 ttgaaagggt tgactgcaaa atcttctgta gagtttgtaa aaaatgagca atattgggat
    11701 aaagaaaatg tccacctaga tactataaat ctagcttact atgatggatc agatcaggag
    11761 tcgctagagc gtaacttcac tagtggagct tatagttatg cccgtcttta ccctaccagc
    11821 tccaactatt ctaaggttgc agaagaatac aaggacaata tctattacac acaatcaggc
    11881 tctgggattg ctggtctggg tgtgaatatt gatcgccaaa gttacaacta tacttctaaa
    11941 actacagatt cagagaaagt agctactaag aaggcattgc ttaacaaaga tttccgtcaa
    12001 gccttgaatt ttgctcttga tcgctcagct tactcagctc aaatcaatgg taaagatgga
    12061 gcagctttag cagttcgtaa tttatttgta aaaccagact ttgtttcagc tggtgagaag
    12121 acctttggtg atttagtcgc tgctcaactt cctgcttatg gtgatgagtg gaaaggtgtg
    12181 aatttagctg atgggcagga tggtttattc aatgctgaca aggccaaggc agagtttgcg
    12241 aaagctaaga aagctttaga agcagacggc gttcagtttc ctattcatct ggacgttcca
    12301 gtagaccaag catcaaaaaa ctatatatct cgtattcagt cctttaaaca atctgtagaa
    12361 acagttcttg gtgttgaaaa tgtcgttgtt gatattcaac aaatgacaag tgatgaattc
    12421 cttaatatta cttactatgc tgccaatgct tcatctgagg attgggatgt atcgggagga
    12481 gtttcatggg ggccagacta tcaagaccca tctacttacc tggatatttt aaaaacaact
    12541 agcagtgaaa ctacaaaaac atatttagga tttgataatc caaatagccc ttcagtagtt
    12601 caagttggtt tgaaagaata cgataaatta gttgatgaag ctgccaaaga gacaagcgac
    12661 ttgaatgtcc gttatgaaaa atatgcagcg gctcaagcat ggttgacaga tagttcactc
    12721 tttattcctg ctatggcttc ttctggtgca gcaccagtgc tttcacgaat tgttccattt
    12781 actggagctt ctgcgcaaac aggctctaag gggtcagatg tttacttcaa atatttgaaa
    12841 ttacaagata aagcggtgac taaggaagag tatgaaaaag ctcgtgaaaa atggttgaaa
    12901 gaaaaagctg aatcaaatga gaaagctcaa aaagaattgg caagtcatgt gaagtaaata
    12961 atttctaata gaactttctc tccatgagga gaaggttctt ttgggatttt taaaggaaat
    13021 aatatgaaaa aatatatttt tatgcgtgtt ttgcggtcat tggtttcgat tttcttagta
    13081 acgactttga cctacacgat tatctatacc ttggttcctc gaaaattgat tttcaagcag
    13141 gatcctaact ataataaaat tgcgacaacg gctgataaac gtgataacta tgaaaatact
    13201 gtgtttgagc gtatgggcta cattgagtat tacgatacta aagagttgca agaaaaggca
    13261 agtagcatgg attcttctgt aacagtagaa gcaaatgcga ccaataaagc tatttatgaa
    13321 aagtacatca atcaattagg tcatggttgg actttgggag aatttactga aagtggtcaa
    13381 ttctatgcta ctcgtgaaat tccaattttt gaacgtgttt ttcacttcta tgctaacttg
    13441 attgacattg accatacaaa taaaatccaa gaccctgaaa atccagactt gaaacgctac
    13501 cttcgttttg aaaacgatcc agctatcgga tggtcattgg tcggttcagg aactaaacat
    13561 aaatatctct tgtactttaa cagtcagttc ccatttgttc atcaaaactt tgtgaacttg
    13621 aatttaggtg actcttaccc aacctatgct aatacaccag ttcttcaggt tattactcaa
    13681 ggtcaaggac aaaccaaaac tgcccaagtt cagttcccaa caggtaagaa aacgtcttct
    13741 gtaaatattt actcaagaac ctacaagtca cctagtcagg ctgactctcg tgaagtagct
    13801 agctatggga aagatgatcc ttatacagcg actgaaagta attaccaata tccatctatg
    13861 attgtcagct ctgctattac tggtttgatt ggtttggttc ttgcctatgc tcttgccgtg
    13921 ccacttggtt cagccatggc tcgtttcaag aacacttgga ttgatagcct ctcaacaggg
    13981 gctttgacct tcttgcttgc tcttccaacg attgccttgg tttacatcgt tcgattgatt
    14041 ggatcatcta tttcccttcc agattcattc cctatcttgg gagctggaga ttggcgttct
    14101 tacgttttac cagcagtcat ccttggtttg ttgggtgctc ctggtacagc catttggatt
    14161 cgtcgttaca tgattgactt gcaatctcaa gactttgttc gtttcgctcg tgcaaaaggt
    14221 ttgtctgaaa aagaaatttc aaacaaacac atctttaaaa atgccatggt tccgctggtt
    14281 tcaggaattc ctggtgccat tattggggtt atcggtggtg caacccttac tgaaacagtc
    14341 ttcgccttcc caggtatggg taaaatgttg attgactctg taaaagcatc taataactct
    14401 atggtcgttg gtcttgtctt catctttaca tgtatttcta tcttctcacg tcttttggga
    14461 gatatttgga tgactattat tgacccacgt attaaattga ctgagaaagg aggcaaataa
    14521 tgtctacaat cgataaagaa aaatttcagt ttgtaaaacg tgacgatttt gcctctgaaa
    14581 ctattgatgc gccagcatat tcttactgga aatcagtgtt taaacaattt atgaagaaaa
    14641 aatcaactgt agtcatgttg ggaatcttgg tagccatcat tttgataagt ttcatctacc
    14701 caatgttttc taagtttgat ttcaatgatg tcagcaaggt aaacgacttt agtgttcgtt
    14761 atatcaagcc aaatgcggag cattggttcg gtactgacag taacggtaaa tcgctctttg
    14821 acggtgtctg gttcggagct cgtaactcca tcctcatttc tgtgattgcg acagtgatta
    14881 acttggttat cggtgttttt gtcggtggta tttggggtat ttcaaaatca gttgaccgtg
    14941 tcatgatgga agtttacaac gtcatctcaa acatcccacc tcttttgatt gttattgtct
    15001 tgacttactc aatcggagct ggattctgga atctgatttt tgccatgagc gtaacaacat
    15061 ggattggtat tgccttcatg atccgtgtgc aaatcttgcg ctatcgtgac ttggaataca
    15121 acttggcgtc acgtactttg ggaacaccaa ccttgaagat tgttgccaaa aatatcatgc
    15181 ctcaattggt atctgttatt gtgacaacca tgactcaaat gcttccaagc tttatctcat
    15241 acgaagcctt cttgtctttc ttcggtcttg gattaccgat tacagtgcca agtttgggtc
    15301 gtttgatttc ggattattca caaaacgtaa caaccaatgc ttacttgttc tggattccat
    15361 tgacaaccct tgtcttggta tccttgtccc ttttcgtagt tggtcaaaac ttagcggatg
    15421 ctagtgatcc acgtacacat agataggagt agaaatgaca aaagaaaaaa atgtaatttt
    15481 gactgctcgc gatattgtcg tggaatttga cgttcgtgac aaagtattga cagccattcg
    15541 cggcgtttcc cttgaactag tcgaaggaga agtattagcc ttggtaggtg agtcaggatc
    15601 aggtaaatct gttttgacaa agaccttcac aggtatgctc gaagaaaatg gtcgcattgc
    15661 ccaaggtagt attgactacc gtggtcagga cttgacagct ttatcttctc acaaggattg
    15721 ggaacaaatt cgtggtgcta agattgcgac tatcttccag gacccaatga ctagtttgga
    15781 ccccattaaa acaattggta gtcagattac agaagttatt gtaaaacacc aaggaaaaac
    15841 agctaaagaa gcgaaagaat tggccattga ctacatgaat aaggttggca ttccagacgc
    15901 agatagacgt tttaatgaat acccattcca atattctgga ggaatgcgtc aacgtatcgt
    15961 tattgcgatt gcccttgcct gccgacctga tgtcttgatc tgtgatgagc caacaactgc
    16021 cttggatgta actattcaag ctcagattat tgatttgcta aaatctttac aaaacgagta
    16081 tcatttcaca acaatcttta ttacccacga ccttggtgtg gtggcaagta ttgcggataa
    16141 ggtagcggtt atgtatgcag gagaaatcgt tgagtatgga acggttgagg aagtcttcta
    16201 tgaccctcgc catccatata catggagtct cttgtctagc ttgcctcagc ttgctgatga
    16261 taaaggggat ctttactcaa tcccaggaac acctccgtca ctttatactg acctgaaagg
    16321 ggatgctttt gctttgcgtt ctgactacgc aatgcagatt gacttcgaac aaaaagctcc
    16381 tcaattctca gtatcaaaga cacattgggc taaaacttgg cttcttcatg aggatgctcc
    16441 aaaagtagaa aaaccagctg tgattgcaaa tctccatgat aagatccgtg aaaaaatggg
    16501 atttgcccat ctggctgact aggaggaagg aaatgtctga aaaattagta gaaatcaaag
    16561 atttagaaat ttccttcggt gaaggaagta agaagtttgt cgcggttaaa aatgctaact
    16621 tctttatcaa caagggagaa actttctcgc ttgtaggtga gtccggtagt gggaaaacaa
    16681 ctattggtcg tgctatcatc ggtctaaatg atacaagtaa tggagatatc atttttgatg
    16741 gtcaaaagat taatggtaag aaatcgcgtg aacaagctgc ggaattgatt cgtcgaatcc
    16801 agatgatttt ccaagaccct gccgcaagtt tgaatgaacg tgcgactgtt gattatatta
    16861 tttctgaagg tctttacaat caccgtttat ttaaggatga agaagaacgt aaagagaaag
    16921 ttcaaaatat tatccgtgaa gtaggtcttc ttgctgagca cttgactcgt taccctcatg
    16981 aattctcagg cggtcaacgt caacgtatcg gtattgcccg tgccttggtc atgcaaccag
    17041 actttgttat tgcagatgag ccaatttcag ccttggacgt ttctgtacgt gcccaagtct
    17101 tgaacttgct caaaaaattc caaaaagagc tcggcctgac ctatctcttc atcgcccatg
    17161 acttgtcggt tgttcgcttt atttcagatc gtatcgcagt tatttacaag ggtgttattg
    17221 tagaggttgc agaaacagaa gaattgttta acaatccaat tcacccatat actcaagcct
    17281 tgctttcagc ggtaccaatc ccagatccaa tcttggaacg taagaaggtc ttgaaggttt
    17341 acgacccaag tcaacacgac tatgagactg ataagccatc tatggtagaa atccgtccag
    17401 gtcactatgt ttgggcgaac caagccgaat tggcacgtta tcaaaaagga ctaaactagt
    17461 aatggtttta taatttccat gtcaattttt atggaaatta taaaactttt tttgttggac
    17521 tgatttgaaa aactttgaaa gcttcctgaa agaatttttg aaaaatttta aaaattatga
    17581 aatgttattg acaggtgatg aaaaaggtgg taggacagga agcatcaaaa aagaaagcag
    17641 aaaaagaaat gaataagaga caagccgtaa ctatgaatca aaacttttac tttagctact
    17701 ttagatagtg tttgtagaca tgtcaccatg gatgcaaaca gttcaagcaa tttgtttgta
    17761 tctatgtggc taagattttt gattgtggtc catatagatg aatatctaaa tggactagct
    17821 aagttgtaac ttgttaggtt atttcaagta tccgtttaga tagtatctag gcggtttttt
    17881 gttttatctt ttctgagaag gagtttcatt atgaaagttg ttcgaaaatc actagccccc
    17941 tcttggtagt ggggctcctc ttgacttctc tgatcagttt gcatcagttg aaggcagata
    18001 agaaaaagat gtctttcgta tcggtatttc gcaatttatt acccaccagt ccttatacgc
    18061 tactagagaa ggatttgtgg atgagctggc caaacaaggc tatgttgagg gggaaaatat
    18121 tgagattgat ttgcaaaatg cacagggaga acaaagaaat ctaaaaacga tttcccagca
    18181 actagcagaa tccagcgatg tcgttctagc catcgcaagg ccttctgctc agagcttggc
    18241 caatacgacg caaacgacac cagttatctt ttcagctgta acagacccag tcagtgccaa
    18301 gttggttgag tcaagagaac atcctggggg caatgtaact gggacaagcg atcagtcatc
    18361 agatgccatt tcaacccaaa tcaatttgat aaagaaagtg ttgccaaagg ctaaaacgat
    18421 tggaatcctc tatactcaga gcgagcccaa ttcggttgtt caaaaggatg aagctaagcg
    18481 acttctgaaa gaaaaaggct ttaccgttgt tgaaaaaaca atcttggaca gtaataacgt
    18541 caaggcggca gcagagagtt tgatggcaga ggtggatatg gtttttgtcc caactgataa
    18601 tatcatttcg ttaaccatgg aaacagttaa gcaggtttct attaaacaca aggttccagt
    18661 attcggtggt tcaacagaaa tgattgctgt tggtggcttg tataactacg gaaccaatta
    18721 tgaagaattg gtacgtcaga cagctcgcat gctgattcgt gttttaaaag gtgagaaacc
    18781 agaaaatata gcagttgagt tgcctgaaaa actggaattg cataccaatc aagaaatggc
    18841 agatgcattg ggaattgata ttagtaagtt agaaggcaag gaataaggag gattaagatg
    18901 aattttgtgt tatctagttt atcagaaggt ttgttgtggt cgattgtggc gattggggtc
    18961 tacttgactt tccgtatttt ggatattgcg gatatgactg ctgagggagc ctttcctctg
    19021 ggggcagcag tcgttgtatc acagatacag gcaggggcaa atccttggct tgcgacttta
    19081 cttgctttgc tgacaggtat ggtagcaggt cttgtatcag gaatgctcca caccaagatg
    19141 aaaatcccag ctctcttgac agggattgtg accttgacag ggctctattc aatcaatatt
    19201 aaaatcatgg gcagtgtacc caatctttcc ttgggagatt ctgcaaccgt ctttaaacag
    19261 ttggcgagct tgggtctgac aaatgaagga actgttttct cacttagttt ggcctgtttt
    19321 ttacttgttt gtttggtctt gacccttttg atgaaaacag agattggcct ggtcttgcgt
    19381 tcgactgggg ataatatccc gatgagtgag gccaatggag tcaatgtaga caccatgaag
    19441 attgttggtt acatgatttc aaacggtttg attgctctat gtggttcctt gtttgcccaa
    19501 aatgatggat tttcagatgt gacttctggg acaggaacca ttgttgttgg tttgagctcg
    19561 gtgattattg cggaagtctt gatacacgac ttgaccattg gaggccgctt attatccatc
    19621 ggaatcggtg ctattgttta ccgtttgatt attttaaata tctatgaaat tccaaatcta
    19681 gatcaaaact tggtacgtct ctttaatgca atcttgctcg ctttggtttt atttgcacca
    19741 gaattgcaaa agagattaaa gattcgtggt ctgaaattga gaaatgaata ggaggagaaa
    19801 gttatgacaa gtttgttaac acttgaaaat attcacaaga catttgaagc agggacggtc
    19861 aatgagaacc atgtcctcaa aggattagat ttagaggttg aagagggaga ttttatctct
    19921 gtgattggtg gaaatggagc aggaaaatcc actttgatga atatcttggc tggcaatcta
    19981 tcggtggacg aaggggacct tctactggca gggaaatcca ttaaaaatct gagtgtcaga
    20041 aagagagcca aggatattgc ccgtgttttt caagatccta agatgggaac agcttctcgt
    20101 ttgacgattg aggagaatat ggctattgcc ttgagacgcg ggcagaagag agggcttggt
    20161 tggggcgtga aggagaagga tagaatccag ttccaagagg ccttgaagga gttgaatatt
    20221 ggtcttgaaa accgcttaaa agtagatact caatatctct caggaggaca aagacaggct
    20281 ttgactctag tcatgacaga tctgatgaaa ccaaaacttt tacttttgga tgaacatact
    20341 gcggcacttg acccgaaaac cagtcaaatg gtgatggact tgacgcaaaa gattgtggag
    20401 caccatcagt ggacgacttt gatgattacc catgatatga atcatgcgat tgagtacggc
    20461 aatcgtctca ttatgctcta tcaaggcaag atagtggtgg atgtcaaggg agaagagaaa
    20521 aagcatctga cagttgaaga ccttatgcat ctcttccaga aaaatagtgg ccaaagtctg
    20581 gtcagtgatg aattagtttt gggataaaga aaaaggctga gatctggtgt ctcagtcttt
    20641 tatttcttgc gttttgcaaa atctacaaat ctaaatttct ctaacttatg gcgactttcg
    20701 gtaaactgaa attggcgtcc gtcttggaga tagacttttg atttaatcga aacgacataa
    20761 gggtctttgc caatgtccat gagaatcttg tctcggtcgc ttgagtggtc aatggtgatt
    20821 tccttctgag cataatcaat aaggagtttg aggccatttt ctatataaga atagatagac
    20881 tgctcagcaa tttggcgagt gagatttgga attagttcca tatccagata gtccgtatcc
    20941 agaacggata ccagatcatc caccacacgc tggcggacca ccttccaaac catccgaaac
    21001 tctgggaaac cggttatcag tgaggatttt ttatcaataa taatcttgtc cagactgacc
    21061 acgttggttt tagagcgcag tccaagttct ttaactagtt cttggtagct ggttaggttg
    21121 gatacaggga aattgacggt ttcttctttg acgacttgag aaccttgctc tcttatcttt
    21181 ttgatcaatc cttcctcttg gaggagagac agggcctttc ggacggtatc acgactcact
    21241 tgatattgct ccataaggtc gtgctcgcta ggaaggaaat ctccgacagc gtaagtctcg
    21301 ttttgaatgg tttcttggat ttgcttaaat aattgttggt atttcttcat tttgcctgct
    21361 ttaataggtt tttagtctag tttaatgaac acctgtatct attttaccat acaagtgcta
    21421 gaaaatttac aaaaaaacac cctttttata ccaaacaagt tgcagacaag tttggtatcg
    21481 tttacaatat acttatcaaa tcaaacttgc tttgacaagt ataaggagaa tcaaatggga
    21541 aaatttgaac aagaagccaa agatctgctt caggcaattg gaggcaaaga aaatgtgact
    21601 gccgtaactc actgtgcgac acggatgcgc tttgttttag gagatgataa gaaggctaat
    21661 gttaaagcta tcgagtcaat tccagctgtt aaaggaactt ttacaaatgc aggtcaattt
    21721 caggtaatca ttggaaatga cgtgcccatc ttttataatg attttacagc cgtttcaggt
    21781 attgagggtg tttccaaaga agcagccaag tctgcagcta agagtaatca aaacgtggtc
    21841 caacgtgtta tgaccactct ggcggagatt tttactccga ttattccagc cttgatagtc
    21901 ggaggattga tcctcggttt ccgtaatgtc ttggaaggtg tccattggtc gatgttggat
    21961 ggcaagacca tcacagaatc ctctcagttt tgggcaggtg tcaatcactt cctctggttg
    22021 cctggtgaag ctatcttcca gttcttacca gtagggatta cttggtctgt ttctcgtaag
    22081 atgggaacca gccaaatttt gggaattgtt ctcggaatct gtttggtatc gcctcagttg
    22141 ctcaatgcct atgcggttgc ttcaacgcca gcagctgata tcgcggcaaa ctgggtttgg
    22201 aattttggct attttactgt taatcgtatc ggttaccaag cccaagttat cccagccttg
    22261 cttgcaggtt tgagtctgtc ttatcttgaa atcttctggc gcaagcatat cccagaagtc
    22321 atttctatga tttttgtacc tttcttgtca ttgattccag ccttgatttt ggctcatact
    22381 gttttgggac caatcggttg gacaattgga caaggacttt catcagttgt cttggcaggt
    22441 ttaactggtc cagttaaagg gctcttcggt gcaatttttg gtgccctcta cgctccattt
    22501 gtcatcacag gtctgcacca tatgaccaat gccattgata cacaattgat tgcggatgct
    22561 ggtggcactg ccctatggcc aatgattgct ctttctaata ttgctcaagg ctcagccgtg
    22621 tttgcctatt atttcatgca tcgccatgat gagcgtgagg ctcaggtttc acttcctgca
    22681 accatttcag cctatctcgg tgttacagaa ccagctcttt ttggggttaa cgtaaaatat
    22741 atttatccat ttgttgctgg gatgactggt tcagcccttg caggcatgtt atccgttact
    22801 tttaatgtaa ctgcggcttc tattggtatc ggtggtttgc caggtattct ctctattcaa
    22861 cctcaataca tgctgccatt tgcaggaact atgctagttg cgattgttgt tccaatgctc
    22921 ttgactttct tcttccgcaa ggctggtctc tttacaaaaa cagagggcga tacgaacttg
    22981 caggcagaat tcgttgctca agaagaagca gaatttgtga accatgaacc agtagaactt
    23041 acttcggtag aaattatcag cccactaact ggccaagtga aagaattgag tcaagcgacg
    23101 gatcctattt ttgcatcagg tgtcatgggg caaggtctgg tcattgaacc aagccaaggt
    23161 gagttgacct ctccagttaa tgggacagtg acggttcttt tccctaccaa gcatgccatc
    23221 ggcattgtct ctgacgaggg agttgaattg ctcatccaca tcggtatgga tacagtaggt
    23281 cttgatggca aaggttttga aagtcttgta gtccaaggag atcacgttac agttggtcag
    23341 caactgattc gttttgatat ggatgtcatt aaggctgcag gtctggtgac agaaactcct
    23401 gttatcatca ccaaccaaga tgcttataca gcgactattc ccggaactta tccgacaacg
    23461 attcaagctg gagcatctct catggtcgct acacgaatct aatactcttc gaaaatctct
    23521 tcaaaccacg tcagctctat ctgcaacctc aaaacagtgt tttgagcaac ctgtggctag
    23581 cttcctagtt tgctctttga ttttcattga gtataattga aatagcacaa atagggacgg
    23641 aagactgctt cctccctttt atcagaaaag gagaaacaga tgacacttga taaaggaaaa
    23701 gtagtctatc aaatctatcc aaaatcttac aaagacacca ctgaaaacgg tattggggat
    23761 ttccgtggga ttatcgaaaa aattccctat ttagccaaac taggcgtgga tatggtctgg
    23821 ctcaatccat tctatccaag ccctcaacgg gataatggtt acgatatttc agattatatg
    23881 gcagtggatc ctctttttgg tgatatggct gattttgagg aaatggtgtg tgtcggtaaa
    23941 gagcacaaga ttgactttat gctggacatg gtacttaatc attgttcgac agagcatgaa
    24001 tggtttcaga aagccctagc tggtgataag tattatcaag actttttctt catccaagac
    24061 caaccaacag attggcagtc taagtttggt ggttctgcat gggcgccttt cggggatact
    24121 gggaaatact atcttcacct atttgatgag acccaggctg accttaactg gcgcaattcc
    24181 aatgtccgta aggagctttt caaggttgtt aatttctggc gcgacaaggg tgtcaaaggt
    24241 ttccgatttg atgtgatcaa tttgatcggt aaggacgagg tttcagtgga ctgtcctgaa
    24301 aatgaaggga agccagctta tacagacaaa cccatcgttc ataactattt gcgtatgatg
    24361 aaccaagcca cttttggatc tgacgatagc tttatgacag ttggggaaat gtcttctacc
    24421 accatggaaa actgtgtcct ctattcgtcg cctgatcgtc aggaattatc catgaccttt
    24481 aattttcatc acctcaaggt ggactataag gatggacaaa agtggacctt ggctcccttt
    24541 gattttgaag agttgaagag tctttaccat agttggggta aggaaatgag tgataaagac
    24601 ggttggagtg ccctcttttg gaacaatcac gatcaaccac gtgccttgaa ccgttttgtc
    24661 gatattcaaa acttccgcaa ggaaggagcc accatgctag cagccagcat tcacctgtca
    24721 cgtgggacac cttatatcta catgggtgag gaaatcggga tgattgaccc agactatgat
    24781 tctatggctg attatgtgga tgtcgaatcg cttaatgcct atcagatgct cttagaagaa
    24841 ggaaagagtc agcaagaagc cttccagatt attcaagcta agtcgcgtga taattcacgt
    24901 attcccatgc agtgggatac ttctgaaaat gcaggatttt caacaggcac tccatggttg
    24961 aaagtcggta aatcctataa agatatcaat gtagaaaatg aaatcaaagg tctgattttc
    25021 accttctatc aagacttgat tcgactgcgt aaggaaatgc caatcatttc agaaggaaat
    25081 tacaaaccag cctttgaaga tagcaaacaa gtctacgctt ttgaacgcca gtttgaggat
    25141 caaaagttac tagtgctcaa taacttttat gccaaagaag tggaaatcga cttgccagca
    25201 gtctaccaaa atggacagat tttgatttca aactatgaag atgcagaagt gtctgagaaa
    25261 attctactca aaccctatca aacactggct atttatgtaa attaatactc ttcgaaaatc
    25321 tcttcaaacc gtgtcagttt tatctgtaac ctcaaagcgg tgctttgagc aacctgtggc
    25381 tagcttccta gtttgctctt tgattttcat tgagtataaa cttagcaagg agacctcttt
    25441 ttcagaaaag cagggttctt tttgctgtct attccatcct tgaaagtgta gaacaaactg
    25501 gtcagggtgg ctagtttgtg gtataatgaa agggattcaa aaagaaacag gagaaaaatg
    25561 atggatttac ttttagcaat tgtattgatt gtgctagctt ttctaggagg agctcttgga
    25621 ggaatgtact tggttcgtaa gcaaatcgaa aaagaatttg ctgacaaccc acgtttgaat
    25681 gctgaagcag ttcgtactct tttgagtgca aatggtcaaa aaccaagcga agctaaggta
    25741 caacaagttt accaccaaat catccgccaa caaaaggcag cccttgctaa caataaaaag
    25801 aaaaaataaa taaggaaaag tctgggatga aagttccaga cttctcacta tgttggttat
    25861 ggtttaggga tgagactttt tccttgcatt ctattgatat ttgattatga ttaagagaga
    25921 ggtagttgac attctatcaa gctgtcggtc agttcgttca gtacaaggaa tcataatgaa
    25981 cgatcaatca gaaaaaagac tagaaagaag actgtatgga taatcgacca attggttttt
    26041 tggattcggg tgtcgggggc ttgaccgttg tgcgcgagct catgcgccag cttccccatg
    26101 aagaaatcgt ctatattgga gattcggcgc gggcgcccta tggcccccgt cctgctgagc
    26161 aaattcgtga atatacttgg cagctggtca actttctctt gaccaaggat gtcaaaatga
    26221 ttgtcattgc ttgtaacact gcgactgcgg tcgtctggga agaaatcaag gctcaactag
    26281 atattcctgt cttgggtgta attttgccag gagcttcggc agccatcaag tccagtcaag
    26341 gtgggaaaat cggagtgatt ggaacgccca tgacggtaca atcagacata taccgtcaga
    26401 aaatccatga tctggatccc gacttacagg tggagagctt ggcctgtccc aagtttgctc
    26461 ccttggttga gtcaggtgcc ctgtcaacca gtgttaccaa gaaggtggtc tatgaaaccc
    26521 tgcgtccctt ggttggaaag gtggatagcc tgattttggg ctgtactcat tatccactcc
    26581 ttcgccctat tatccaaaat gtgatggggc caaaggttca gctcatcgat agtggggcag
    26641 agtgcgtacg ggatatctca gtcttactca attattttga aatcaatcgt ggtcgcgatg
    26701 ctggaccact ccatcaccgt ttttacacaa cagccagtag ccaaagtttt gcacaaattg
    26761 gtgaagaatg gctggaaaaa gagattcatg tggagcatgt agaattatga caaataaaat
    26821 ttatgaatat aaggatgacc aggactggta tgttgggtct tatagtattt ttggtggcgt
    26881 taacagtttg agcgactata agacagattt tcctctgttt gaattctcca aaatatttgg
    26941 agatgaagag tatggtttcc cgctttcagt tactgtttta cgctatggtt ctacctaccg
    27001 tttgttctcc tttgtggtag acatgcttaa tcaagaaatg ggacgaaact tggaagttat
    27061 tcaacgtcat ggggccctgc tcttggttga aaatgggcaa ctcttgtatg tagaattgcc
    27121 taaagaaggg gtcaatgttc atgatttctt tgagacaagc aaggtcagag aaaccttgtt
    27181 gattgcgact cgtaacgaag gtaaaaccaa ggaattccga gctatctttg ataagttagg
    27241 ctacgatgtg gaaaatctta atgactaccc tgacctgcct gaagtagcag aaacaggtat
    27301 gacctttgaa gaaaatgccc gccttaaggc agaaaccatt tctcaattaa cgggcaagat
    27361 ggttttggca gatgattctg gtctcaaagt cgatgtcctt ggtggcttac caggcgtctg
    27421 gtcagctcgt ttcgcaggtg tgggagcaac tgaccgtgaa aataatgcca aactcttgca
    27481 cgaattggcc atggtctttg aactcaagga ccgctcggct cagttccaca caaccctagt
    27541 cgtagccagc ccaaataagg aaagtttagt tgttgaagca gactggtcag gttatattaa
    27601 ctttgaacct aagggtgaaa atggctttgg ctatgatccc ctcttccttg taggagagac
    27661 aggtgagtca tcagctgaat taaccctaga agaaaaaaat agtcaatctc accgtgcctt
    27721 agccgttaag aaacttttgg aggtatttcc atcatggcaa agcaaaccat cattgtaatg
    27781 agcgattccc atggcgatag cttgattgtg gaagaagtcc gtgatcgcta tgtgggcaaa
    27841 gtcgatgccg tttttcataa cggcgattct gaactacgtc cggattctcc actttgggag
    27901 ggcatccgcg ttgttaaagg gaacatggac ttctacgccg gctacccaga acgtctggtg
    27961 actgagcttg gttcgaccaa gattatccaa actcatggtc acttgtttga catcaatttc
    28021 aactttcaaa agttggacta ctgggctcag gaggaagagg ccgctatctg cctctatggt
    28081 cacttgcatg tgccaagtgc ttggttggaa ggcaagatcc tctttctaaa tccaggttct
    28141 atcagtcaac cacgaggtac catcagagaa tgtctctatg ctcgtgtgga gattgatgat
    28201 agttacttca aagtggactt tttgacacga gatcacgagg tgtatccagg tttgtccaag
    28261 gagtttagcc gatgattgcc aaggagtttg agactttctt gttggggcag gaggaaactt
    28321 ttttgacccc tgctaaaaat ctagctgtgt tgattgatac ccacaatgcg gatcatgcga
    28381 ccctcttgct cagtcagatg acctataccc gtgttcccgt tgtgacagat gaaaaacagt
    28441 ttgttgggac gattggactc agagatatta tggcttatca gatggagcat gacttgagcc
    28501 aagaaatcat ggcggatacg gatatcgttc atatgacaaa aacggacgta gcggttgttt
    28561 cgcctgattt caccattacg gaggtcttgc acaagctagt agatgagtcc ttcttaccgg
    28621 tcgtggatgc agagggtatt ttccaaggga ttattacgcg caagtccatc ctcaaggccg
    28681 ttaatgccct cttgcatgac tttagtaagg aatatgagat tcgatgccaa tgagagacag
    28741 gatttcagcc tttttagagg aaaagcaggg cttgtctgtc aattccaagc agtcctataa
    28801 gtatgatttg gagcaatttt tagacatggt aggtgagcgg atttctgaga ccagtctcaa
    28861 gatttaccaa gcccagctag ccaatctaaa aatcagcgcc cagaagcgaa agatttcggc
    28921 ctgtaaccaa tttctatact ttctctatca aaaaggagag gtggacagct tttaccgctt
    28981 ggaattagcc aaacaagctg aaaagaagac ggaaaagcca gagattctat acctagactc
    29041 tttttggcag gaaagcgacc atccagaggg ccgcttgcta gcgctcttaa tcctagaaat
    29101 ggggctcttg cccagtgaga ttttagccat caaggttgcg gacatcaatc tggattttca
    29161 ggtgctgcga atcagcaagg cttcccaaca gaggattgtc accattccca cggccttgct
    29221 ttcagaattg gaacccttga tggggcagac ctatcttttt gaaagaggag agaaacccta
    29281 ttctcgtcag tgggcctttc gtcagttaga atcttttgtc aaggagaaag gttttccatc
    29341 cttatcagct caagtcttac gtgaacagtt tattctaaga caaatagaaa acaaggtcga
    29401 tttgtacgaa attgcaaaaa aattaggatt aaaaacagtc ctgaccttag aaaaatatag
    29461 ataatggata ttaaattaaa agattttgaa ggacccctgg acttgctctt gcatctggtt
    29521 tctaagtacc agatggatat ctacgatgtg cccattacgg aagtcatcga acagtatcta
    29581 gcctatgtct caaccctgca ggccatgcgt ctggaagtga cgggtgagta catggtcatg
    29641 gctagtcagc tcatgctgat taagagtcgt aaactccttc cgaaggtagc agaagtgaca
    29701 gacttggggg atgacctgga gcaggacctc ctctctcaaa tcgaagaata tcgcaagttc
    29761 aagctcttgg gtgagcactt ggaagccaag caccaagaac gggcccagta ttattccaaa
    29821 gcgccgacag agttgattta cgaagatgcg gagcttgtgc atgacaagac gaccattgac
    29881 ctctttttgg ctttttcaaa tatcctagcc aagaaaaaag aggagtttgc acaaaatcac
    29941 acgacgatct tgcgggatga gtataagatt gaggacatga tgattatcgt gaaagagtcc
    30001 ttgattggac gagatcaatt gcgcttgcag gatttgttca aggaagccca gaatgtccaa
    30061 gaggtcatca ccctcttttt ggcaacccta gagttaatca aaacccagga gctgatcctc
    30121 gtgcaagagg agagttttgg agatatctat ctcatggaaa agaaggaaga aagtcaagtg
    30181 cctcaaagct agacttgata gagaggaaag atgagtactt tagcaaaaat agaagcgctc
    30241 ttgtttgtag cgggtgaaga tgggattcgg gtccgccagt tagctgaact cctctctctg
    30301 ccaccgacag gcatccagca aagtttagga aaattagccc agaagtatga aaaggaccca
    30361 gattccagtt tggctttgat tgagacaagt ggtgcttata gattggtgac caagcctcaa
    30421 tttgcagaga ttttgaagga atactctaag gcgcctatca accagagctt gtctcgggct
    30481 gcccttgaga ccttgtccat tattgcctac aaacagccga ttacgcggat agaaattgat
    30541 gccatccgtg gagttaactc gagtggagcc ttggcaaagt tgcaggcttt tgacctgata
    30601 aaggaagacg ggaaaaagga agtattgggg cgccccaacc tctatgtgac tacggattat
    30661 ttcctagatt acatggggat aaaccattta gaagaattac cagtgattga tgagcttgag
    30721 attcaagccc aagaaagcca attatttggt gaaaggatag aagaagatga gaatcaataa
    30781 gtatattgcc cacgcaggtg tggccagtag gagaaaagca gaagagctga ttaagcaagg
    30841 cttggtgacg gttaacggcc aagtggtgcg tgaactagca accactatca agtcaggcga
    30901 caaggtcgaa gttgaaggtc aacctatcta caacgaagaa aaggtctact atctgcttaa
    30961 caaaccacgc ggtgtgattt ccagtgtgac agatgataag ggtcgcaaga cggttgtcga
    31021 cctcttgccc aatgtcaaag agcgtattta ccctgtgggt cgtttggact gggatacatc
    31081 aggtgtcttg attttgacca atgatgggga ctttacagac gagatgattc accctcgtaa
    31141 tgagattgac aaggtttatg tcgcgcgtgt taaaggtgtg gccaataagg acaatctccg
    31201 ccccttgacc cgtggtcttg agattgatgg taagaaaacc aagccagctg tttatgaaat
    31261 tctcaaagtg gacccagtca aaaatcgctc tgtggtgcag ttgaccatcc atgaagggcg
    31321 taaccatcag gttaaaaaga tgtttgaagc tgttggtctc caagtagata agttgtctcg
    31381 gactcgtttc ggacacctag acttgacagg actccgtcca ggagaatccc gtcgtcttaa
    31441 taaaaaagaa atcagccaac tacacaccat ggctgtaact aagaaataat gaaacgaatt
    31501 ttaatagcgc ctgtgcgctt ttaccaacgt tttatctcac cagtctttcc accctcttgt
    31561 cgctttgagc tgacttgttc caactacatg attcaggcta ttgaaaaaca tggttttaag
    31621 ggggtattga tgggcttggc tcggatttta cgttgtcatc cctggtcgaa aacaggtaag
    31681 gaccccgttc cagaccactt ttcccttaaa cgaaatcaag aaggggaatg aggtggggta
    31741 aatagatttc aaaatgataa aaacgcatcc tatcaggttt gagtaaactt gataggatgc
    31801 gttttagaat gtcaaaattt tatactcttc gaaaatctct tcaaaccgcg tcagctttca
    31861 tctgcaacct caaaacagtg ttttgagcaa cctgcggcta gtttcctagt ttgctctttg
    31921 attttcattg agtattaaat tgagtttgaa gtggcttatt tcaaagcttt ttgtatgtct
    31981 tcaatcatga gttttgttga ttcaagtccg cctccgctta gataccagag gtctggtgtt
    32041 agttggataa tcttaccatt tttagcagca ggtgtttcag cgataagggc attttctagg
    32101 acaccgtcgt tgctagagtt gtccccaccg atggcaaggg tacggttgat gacaaagagg
    32161 atgtcagggt tgatttcttt gacactttca aagctgactt cttgtccgtg gcgtgagtct
    32221 tcaaattttg tatcagttgg tttgaatttc aaggtttggt acaagaaaga gaaacgagat
    32281 ttggcaccaa aggctgccat ttttccttca ttaaggagga tcgcaagggc ttttttgtca
    32341 gagctttcat ttttagtagc gacttcttgg atgctcttgt ctagcttggc caattcttcc
    32401 ttggctttct gtgtaccagt ttcgccgaag gcacttgcta aggattcgat attagccttg
    32461 gtagaagtcc agtagtcgtc cttgcttgct tggaagagaa cggttggggc gatttctttg
    32521 aatttgtcta cgaatttttg tgtacgtggt gaagcgataa tcaaatcagg ctcaagggcg
    32581 gcgatagctt ctaaatcagg ttctttcata gaaccaacat ttttgacagt tcccactagg
    32641 tcttttagat aagtcggaac agtttttgta ggcattccga cgatattttt ttcaaatcct
    32701 aaagcgcgaa tagtatccgc agcgccgagg tcaaaggtca caatcttttc aggaactttg
    32761 gaaagtttga cctcggccag tgaactttta atggttacct ctgttggagc agagctactg
    32821 gtctctgtct gactagtgct tgagtttgta ctacatgcac caagtaggag caagaagctg
    32881 gccactaggg cagtgaaata aagtttaagg gatgttttca taatttctcc tctttaaaat
    32941 gtgataacga tttagggagt ctcttgatct tattgactaa gagactgaag gttctctaac
    33001 ttgagctttt atgttactag ctatagatac agatcttttt gtcattgata tcagctagcg
    33061 tgatgggaat ctcataaagt tgactgagca ggtcagcctg catgatttga tcggttcttc
    33121 ccttgctaaa gacctggccg tccttgaagg cgacaatttc atctgcatac tgactggcta
    33181 tgttgatatc gtggaggacg atgataatgg tcttgccgag ttcctccacc agtcgtcgaa
    33241 gaatctgcat catgctgacg ctttgcttga tatcgagatt gttgagtggt tcgtccagca
    33301 agataaagtc cgtatcctgg gccagtacca tagcgataaa gacgcgctgg agttgccccc
    33361 ctgacaggct attgatgtag cggtctttta agttggtcag ttccaaatag ttcagagttt
    33421 ctcggatttt ttcccagtct tctgatctaa gtcgacctcg gctgtaggga aaacgtccaa
    33481 aactgaccag ttcttcaaca gtcaatttgg cttggtaatt gattttctgt tttaggatgg
    33541 ttagttcttg ggccagttct tgcgaattcc agctctcgat ttcacgtcct ttgatactga
    33601 gaactccctg atctttcttg gttagtctgc tcatgatgga gaggagagtc gattttccag
    33661 caccatttgg accaataaag gctgtcagtt tttgaggact gacttcaagc gaaatgcctt
    33721 gcaaaatatc ctgtttttga atggatttgt caatgttttc cagtttcact gacgagccct
    33781 cctatatagt aagataaaga ataagaagcc acccacactc tcaatgatca tactgatacg
    33841 aatttccagt gcaaagactc gttcaatcaa ggcttgcccc aaggttaagc taataaatcc
    33901 aaccagaatg gccactataa agagtaactt gtgctgatag tctttgacaa tcaggtaggt
    33961 gaggttggcc agcataaagc cgaagaaggc cataggtcct accaaggcag tggccgttga
    34021 ggtcaaaagc acgattcccc agaggagctc tttctgttct ttttcaacat cgagtcccaa
    34081 tatctgagcc gtttctcttt gcaggtgcaa gacatctaga acgactgctt ttcgaaagaa
    34141 aaagattgtc aaagcgagga tgatcagaga accgatggct aggatggaag tgttgagatg
    34201 ttgaaaggag gcaaaaagac tattttgcag tttatcgtat tcgtttggat ccattaggac
    34261 ttgaaggaag gtgctgatat ttcgaaagag acttctgagc gctagacaga tcagcaggat
    34321 gaagaccagg tcttgcttca tcagtgtctt caagtaacct tgtaaggcga gaaagaagag
    34381 ggactggaca agaagtaaga ctaggaattc taagataggg gatttgccaa gttgaagaaa
    34441 cttgctttca aaaaccagta gtagggtttg tagtaggacg tagaaggatt caattcccaa
    34501 aatactaggc gtcaggaagc gattttccgt cagggtttga aaactaatgg tcgaaatccc
    34561 agtcgcgatg gctaccaaga gataaacgat gatcttttgg gaacgcaact tccaagcaaa
    34621 ggctgacaag tgagtgatgg gccaaaagta gagaagacaa gctccgatgg caagaataat
    34681 gagaatccag aagagcttgg tatgtttgct tttagtctgc atcttttcgt ccccctctcc
    34741 agagaagtag gataaagacg agactaccga tgattcctag caagagactg acagacaact
    34801 catagggcct aatcagaact cgggatagga tatcgcaagc cagaactaga ttggcaccaa
    34861 ccagtgcgac catgagtttg gtttgactta gattatctcc atagcgcttg cgaacaagat
    34921 tgggaacgat aactccgaga aatggtaggc cacccacggt aatcatggtg acgcttgtcg
    34981 ttagcgccac cagaaagagg gccagttttt caagtaggga gtaggaaatc cccaaactct
    35041 cgctggtttc tttccctaga ttcatgatgg tgaaggtttg ggataatttc caaacggtta
    35101 tcaggatgat gaggcctaag aagagccact catactgatg ggtctgaatc atggagaagg
    35161 agccctgggt ccaggcagtc atactctgaa ccagattgaa acgataggcg ataacttctg
    35221 tgactgagcc gataatcccg ctatagatga tcccaatcag aggcaacatc cacctttcct
    35281 ttacagtaaa aatggtcata aaggctagga agaagagggt gaatacgatg gatgaaacaa
    35341 aagcgaagag catcttttgg gtcagactag ccgatggaaa gacaaaaagg ctcagcacca
    35401 ttcccagttt ggcggcttca gtcgttccaa ctgtactcgg tgcagcaaac tgattttggg
    35461 taatagtctg catgagaagg cctgccatac tcatactaga ggcagtcagg agaatactga
    35521 tagttcttgg gagacgggac tcttgaaaga ggagccaggt ctgctggtcg aaatcaaata
    35581 gctttcccca tgaaaaatca ctggtcccaa tgctaataga gagaaagact aggagtagaa
    35641 gtaagccaat taaataatga gaaagtttca taccccgtcc tttcatgtag atttggtatc
    35701 gaaagatatc tgcggatata aatgtaacat tatttttcta atctgtcaat aaaatttctg
    35761 acaatttaat aaatacaaca aggagagagc aacaagactt tctcctttgt tatcctattc
    35821 taaaatgttt ttaccttaat ctgataaaat aatatcttcg agggagtagc tagccgtcca
    35881 atcaagatat tgtttagctt ttgaagcatc tgctaggaca ctggctgggt cactagcacg
    35941 tcgagcaaca atctcgtgtg ggatttttta atttagtaat tcttcagcag ttttaaagat
    36001 ttctttgata gtatagcctt ttttagttcc taagttaaag atttgagaag aactgtcttc
    36061 ttgaaatagg tagttcattc ctttaacatg agcctatgca aggtccaaga cataaatgta
    36121 atctcgaata catgaaccgt cacgtgtatc gtagtcatct ccaaatattt ttaagctatc
    36181 attttgtccc aatgcggtct tgttgatatt tggaatgatg tgagttggat ttttcacacg
    36241 cagaccgttt gaagcatcca tttcagcccc agcaacatta aagtaacgga aaataacata
    36301 tttccagtcg tagcgattgg ccatccagta aatcattcgt tcgcccatca gttttgtctc
    36361 tgcataaggg ttgacagggt cgagcagggt atcttcagtc accggcttgt caatacagtt
    36421 atttccatag agagaagcag tcgaagagaa catgattttt tgaatgccaa cttcagataa
    36481 gactttgaga acttggttca taccagcaac gttggcagtg aagtatttac ttggattttc
    36541 aatactttcg ctcacaacaa tttcacctgc acaatggagg acagcatcaa tctgattttc
    36601 ttctaagtaa gcctttaagg cgctagcatc ataaacatcc agttctttaa agctagcacg
    36661 actatccaca gccgctcgat ttcctgtgga gagattatcg aggacatgca ccttatagcc
    36721 agcatttaaa agagctttaa cggtatggga gccaatgtag ctagtcccac ctgtaacaag
    36781 aattgttttg gtcatgattt tttccttttc tagttttgta ctatagtaaa ttgaaataag
    36841 atatgaacaa ctctattagg aaagtcaaat taatttctag aaatgtttca gcagctacag
    36901 cgtactattc caaactcaac caactatata tttaaagaaa gaagaaaggg aagtcaacta
    36961 ttttctgtaa atttcatgaa aaatccaaac aactttgatg gtgtattgtt tttttgtttg
    37021 gaaataaata ttcgagttaa ttttggaatg tttactagat tttgcactac atgcaagaga
    37081 atactatcct tttctaagat agagcaggac taagatacta acttagaaat ccaccttccc
    37141 actatccttc tcctataaaa agtggtaaaa tggatgaaag aaagaaggaa ctgaaatgac
    37201 aacattattt tcaaaaatta aagaagtaac agaacttgct gcagtctcag gtcatgaagc
    37261 gcctgtccgt gcttatcttc gtgaaaagtt gacaccgcat gtggatgaag tggtgacaga
    37321 tggcttgggt ggtatttttg gtatcaaaca ttcagaagct gtggatgcac cgcgcgtctt
    37381 ggtcgcttct catatggacg aagttggttt tatggtcagc gaaatcaagc cagatggtac
    37441 cttccgtgtc gtagaaatcg gtggctggaa ccccatggtg gttagcagcc aacgtttcaa
    37501 actcttgact cgtgatggtc atgaaattcc tgtgatttca ggttctgttc ctccgcattt
    37561 gactcgtgga aaggggggac caaccatgcc agccattgcc gatatcgttt ttgatggtgg
    37621 ttttgcggac aaggctgagg cagaaagttt tggcatccgt cctggtgata ccatcgtacc
    37681 agatagttct gcaattttga cagccaatga aaaaaatatc atctcaaaag cttgggataa
    37741 ccgctacggt gtcctcatgg taagcgagct agctgaagct ttatcaggtc aaaaactcgg
    37801 caatgaactc tatctgggtt ctaacgtcca agaagaagtt ggtctgcgtg gcgctcatac
    37861 ctctacaacc aagtttgacc cagaagtctt cctcgcagtt gattgctcac cagcaggtga
    37921 tgtctacggt ggtcaaggca agattggaga tggaaccttg attcgtttct atgatccagg
    37981 tcacttgctt ctcccaggga tgaaggattt ccttttgaca acggctgaag aagctggtat
    38041 caagtaccaa tactactgtg gtaaaggcgg aacagatgca ggtgcagctc atctgaaaaa
    38101 tggtggtgtc ccatcaacaa ctatcggtgt ctgcgctcgt tatatccatt ctcaccaaac
    38161 cctctatgca atggatgact tcctagaagc gcaagctttc ttacaagcct tggtgaagaa
    38221 attggatcgt tcaacggttg atttgattaa acattattaa accataaggg aggtggtagg
    38281 gatggtagaa ccaaacctag aaagccttat aaaagatctt tacaatcatg ctcgacatga
    38341 tttgagtgaa gatttagttg ctgctctcct agagactact aaaaaactgc ctactacaaa
    38401 tgagcaattg caggcagttc gtctctcaag cctggtcaat cgtgaattgc tcctaaatcc
    38461 caaacatcca gcacctgagt tgctcaactt ggctcgcttt gtcaaaagag aagaagccaa
    38521 gtacagagga actgcgactt ctgcgcttat gtatgaggaa ctttttaaaa tgctttgatt
    38581 ccattgtgga tcaaagcatt ttttataaga cctatctcgt gagcgttcaa atagtagtaa
    38641 caaggaatca tgagaagtca gccgagacca tagtagtgaa gaaacttctg taatggaagt
    38701 ggagtgaagt gaggaatcat caaacggtag gggataggct gtttgaaggg tgctacgaaa
    38761 aagatagggt aaggtgaaat tatagcggaa tgaaataaga tatgaacaaa ttgattaggg
    38821 aaatcaaatg aatttataga aatcttttag cagtcatggc gtcctattct agtttcaaaa
    38881 tgctataaat acgaacaaat tgattgggaa attcaaatcg ctttctatca atgttttaga
    38941 agatacagtg ccctagtcca acttcaatat actataaaag aacagatgga agcaattatg
    39001 atttacttct atctttaaaa taaatgatct gataggaaaa atgtgtcccc tcataaaaaa
    39061 taggatagta cggatggaag gcttttgtag actggaggac gaaggaattt agaaactctc
    39121 gttaaaagtt agttgagccg gagtatggtg gtgtgaataa ttatcaaaaa ttatttccaa
    39181 atcgaaatag ttgacagtta gaacgatgag tgttacaatt attttattca tttcgatatc
    39241 gaaataaatt ggaggtgtta tgaaagatag tcatttgcta gcccatcata ttcgtttgtt
    39301 gaatgggcgg atttttcaaa agttactgag tcaagatcct gaggctcttt ataggggtga
    39361 acagggcaag attttagcgg ttttatggaa tagtgaaact ggctgcgcaa ctgcgacaga
    39421 tatcgcgctt gcgactgggc ttgcgaataa tacgctgacg actatgataa aaaagctaga
    39481 ggaacaaaag cttgtaattg ttagtccgtg tggaaaagac aagcgtaaga agtatttagt
    39541 tttaacggag ttaggcaagt tccagaaaga agtggggcat cgtgtcagtc agaaattgga
    39601 tactatcttt tacaaaggat tttcagagga agaaattcac caatttgaag gttttcaaga
    39661 aagaattttg gcaaatctga aagagaagga aaatgaggtt tagaatatgt cacaacaagt
    39721 gaaaaatgct cacaacctat acatccatgc cattcaagac ggacgagttg ctgaggctca
    39781 agcccagtct gtaggggata cctatatcca acattcgaca ggtgttcctg acgggaaaga
    39841 aggatttgca gccttctttg cagatttctt tgagcgtcat ccagagcgtc agattaagat
    39901 tgtccgcacc attgaggatg gcaatctggt ctttgttcat gttcatcaat atctgaatgg
    39961 tggagaagct caatgggtga cgacggatac tttccgtgcg gatgagaatg gtcgtattgt
    40021 tgagcattgg gatgtcattg actactatcg aacacctgaa aatgaccaac tagatcaaat
    40081 ttttggagat tttgaaatca aggatttgga caagaaagca gaaaataaaa agctggttcg
    40141 ccgtttcttg acagaaactt tccaaaatgg ggagctagag cagtggagtg attatgtggc
    40201 agacgatttg attcagcata atcatgagat tggacaagga agtgctgctt ataaaaacta
    40261 tgtggctgaa tatagtgtca cttttgactt tgttttccaa ctcttaggac aaggaaacta
    40321 tgtggttagc tatggtcaga ctcagattga tggcgttgct tatgcccagt acgatatctt
    40381 ccgtttagag aacgggaaaa ttgtggagca ttgggataat aaggaagtca tacctaaggt
    40441 agaagacttg actaatcgag ggaagtttta aattgaggac aaagaatgat tgaatacaaa
    40501 aatgtagcac tgcgctacac agaaaaagat gtcttgagag atgtcaattt acagattgag
    40561 aatggggagt tcatggtttt agttgggcct tctgggtcag gtaagacgac catgattaag
    40621 atgattaacc gtctcttgga accaactgat ggaaatattt atatggatgg caagcgcatc
    40681 aaagactatg atgagcgtga acttcgtctt actactggat atgttttaca ggctattgct
    40741 ctctttccca atctaacagt tgaggaaaat attgctctca ttcctgaaat gaagggttgg
    40801 actaaggaag aaattgctca aaaaacagaa gagcttttgg caaaagttgg attaccagta
    40861 gctgagtatg ggcatcgact tccaagtgag ctatctggtg gagaacagca acgggtcggt
    40921 attgtccgag ctatgattgg tcagcccaag attttcctca tggatgaacc cttttcggcc
    40981 ttggatgcta tttcgagaaa acagttgcag gttctgacaa aagaattgca taaagagttt
    41041 gggatgacaa cgatttttgt aacccatgat acggatgaag ccttgaagtt ggcggaccgt
    41101 attgctgtct tgcaggatgg agaaattcgc caggtagcga atcccgagac aattttaaaa
    41161 gtgcctgcaa cagactttgt agcagacttg tttggaggta gtgttcatga ctaatttaat
    41221 tgcaactttt caggatcgtt ttagtgattg gttgacagcc ctatctcaac atttgcagtt
    41281 gtcacttttg accttgttac tagctatttt gcttgcgatt cccttggctg tttatcttcg
    41341 ctatcatgag aagttggcgg attgggtctt acagattgca gggattttcc agaccatccc
    41401 gtctctggcc ttgttgggac tctttattcc cttgatggga attgggactt taccggcatt
    41461 gacagctcta gtgatttatg cgatttttcc gattttacaa aatactatta ctgggctgaa
    41521 gggaattgat ccgagtcttc aagaggctgg gattgccttt gggatgacca gatgggagcg
    41581 tctcaagaag tttgaaattc cacttgccat gcctgttatc atgtctggaa ttcggacggc
    41641 agcggtcttg attatcggta cggctacctt ggcgaccttg attggggcag ggggactggg
    41701 ttcctttatc ctgttgggaa ttgaccgtaa taatgccagt ttgattttga ttggggccct
    41761 ttcttctgca gtgctagcta ttgcctttaa cttcctacta aaagtaatgg aaaaagcgaa
    41821 attgcggacg attttctctg gttttgcctt ggtggcttta ttactgggtc tgtcttatag
    41881 tccagccctt ttggctcaaa aagagaagga aaacttgatt attgctggga aaataggccc
    41941 agaaccagaa attttggcta atatgtataa attgctgatt gaagaaaata ccagcatgac
    42001 tgcgactgtt aaaccgaatt ttgggacgac aagtttcctt tatgaagctc tgaaaaaagg
    42061 tgatattgac atttatcctg aatttaccgg tacggtgact gaaagtttgc ttcaaccatc
    42121 acccaaggtg agtcatgagc cagagcaggt ttatcaagtg gcgcgtgatg gcattgccaa
    42181 gcaggatcat ctagcctatc tcaaacctat gtcttatcaa aatacctatg ctgtagctgt
    42241 tccgaaaaag attgctcaag aatatggctt gaagaccatt tcggatttga aaaaagtgga
    42301 agggcagctg aaggcaggct ttacgcttga gtttaacgac cgtgaagatg gaaataaggg
    42361 cttgcaatca atgtatggtc tcaatctcaa tgtggcgact atgcagccag ctcttcgtta
    42421 tcaggcaatt cagtcagggg atattcaaat cacggatgcc tattcgactg atgcggaatt
    42481 ggagcgttat gatttacagg tcttggaaga tgacaagcaa ctcttcccac cttatcaagg
    42541 ggctccactc atgaaagaag ctcttctcaa gaaacaccca gagttggaaa gagttcttaa
    42601 tacattggct ggtaagatta cagaaagcca gatgagccag ctcaactacc aagtcggtgt
    42661 tgaaggcaag tcagcaaagc aagtagccaa ggagtttctc caagaacaag gtttgttgaa
    42721 gaaatgatgg gacagagact ttaaacatac tgaactcaac ttccttaaac gactagataa
    42781 aagaatgctc agacaatttc gtctgggctt ttttgatgtg agaatgactg aatgtcactt
    42841 aaaatggaaa gaaagagaaa attttcatga ttttctaaaa ttttactgta aagacagttg
    42901 actattcata aaataggtgt ataatatttt gtgaactact taacaaataa gaggtttcag
    42961 ctcatgtcga ctaaggttag aaatcttgtg tataggcagt tcattatcta atagagcgtt
    43021 gcgtccgaaa gtctatccag acacggctct ttaaaaacaa aaggagaaat gatgcatact
    43081 tatttgcaaa agaaaattga aaatatcaaa acaaccctag gtgaaatgtc aggtggttac
    43141 cgtcgtatgg ttgcggctat ggctgattta ggattttcag gaactatgaa ggctatctgg
    43201 gatgacctct ttgcccatcg tagttttgcc cagtggattt atttgctggt tttaggaagt
    43261 tttcctctct ggctggagtt ggtttacgaa catcgtattg ttgactggat tgggatgatt
    43321 tgtagcttga cagggattat ctgtgtaatc tttgtatcgg aaggtcgagc aagtaattat
    43381 ctttttggct tgattaactc tgttatttac cttattttgg ccctacagaa aggcttttat
    43441 ggtgaggtgc tgacgacact ttacttcaca gtcatgcagc caattggact tctagtttgg
    43501 atttatcagg cacagtttaa gaaggaaaag caggagtttg tcgcgcgtaa actggacggc
    43561 aagggctgga caaagtatct ttccattagt gtgctttggt ggttggcctt tggcttcatt
    43621 tatcagtcta ttggtgccaa tcgtccctat cgtgattcaa tcacagatgc aaccaatggg
    43681 gtagggcaaa tcctcatgac agctgtttac cgtgaacagt ggatattctg ggcggctacc
    43741 aatgtttttt caatctatct ctggtgggga gaaagcctgc aaattcaagg gaaatatcta
    43801 atttatctca ttaacagtct agttggttgg tatcaatgga gcaaggcagc taagcagaat
    43861 actgatttac ttaactagga aaagatgttt gaaagtgctg ttttgagatt tcgattaaaa
    43921 cagatatagt tgataatcaa ggatttatag tatgaaaaag aggatcggcg ggtcctcttt
    43981 tgttgttgaa aagataaaaa actcagtaac ctagaaataa gacaactgag ctttactcta
    44041 tattcaattt ttaggaatga gaaggtctag ataaaattgg acaacttcct ggcctgtgaa
    44101 atcttgacct tttttgagcc accaggtcaa tgtctcgata aagttggaca cgaccaagtg
    44161 ttggaggtaa gaagtaggca tattagggtg ggcttctttt aaattatcag ctagcacgga
    44221 atagacatgg tgttctagct ctttatggag ttgacggagg aagtagtcat ttttggaaaa
    44281 tagcagactg gtgatatggt cttggttttt atgaaaatgg agaaagaggt gggcgaggta
    44341 gtcctcggtt gaaatggctt gctctctttc aaaaagatga tggaagaggt agcggcagag
    44401 ctggtccaga agaagctcct tactttcata gtgacagtaa aaggtggatc ttcccacatc
    44461 tgcgagatca atgatatcct gaacagtagt ggcctcgtag cccttagcat tcaaaagttg
    44521 tataaaagct tgatagatgg cttttttggt tttgctgata cggcggtcaa tgttagtcat
    44581 atggacactt aaggcaaatt gttcagaact gaataaagct gacgttttgc ttctatcctt
    44641 tctttgagtt ttagtggata atgataatga acaaggtgtt cataaatcta ttataacaaa
    44701 ggaatgagaa atatgaaggc aaaatatgct gtttgggtgg cttttttctt aaatttgact
    44761 tatgccattg ttgagtttat tgcaggtgga gtatttggtt ctagcgctgt tcttgctgac
    44821 tctgtgcatg acttgggaga tgcgattgca attggaatat cagcttttct agaaacaatc
    44881 tccaatcgtg aagaagacaa tcagtacacc ttgggctata agcggtttag cctgctagga
    44941 gccttggtaa cagctgtgat tctcgtaacg ggctctgttc tagtcatttt ggaaaatgtc
    45001 acgaagattt tgcatccgca accagtcaat gatgagggga ttctctggtt aggaattatt
    45061 gcgattacta tcaatctgtt agcgagtctg gtggttggta agggaaagac aaagaatgag
    45121 tctattctga gtttgcattt tctggaagat acgctagggt gggtagctgt tatcctgatg
    45181 gcgattgttc ttcgatttac ggactggtat atcctagatc ctcttttgtc ccttgtcatt
    45241 tctttcttta ttctttcaaa agcccttcca cgtttttggt ctacactcaa gattttcttg
    45301 gatgctgtgc cagaaggtct tgatatcaag caagtaaaga gtggcctgga gcgattggac
    45361 aatgtggcca gccttaatca gcttaatctc tggactatgg atgctttgga aaaaaatgcc
    45421 attgtccatg tttgtctaaa agaaatggaa catatggaaa cttgtaaaga gtctattcga
    45481 attttcctaa aagattgtgg ttttcaaaat attaccattg aaattgatgc tgacctagaa
    45541 actcaccaaa cccataagcg aaaggtgtgt gacttggaac ggagttatga gcatcaacat
    45601 tagaaaaaag tgaaaaatac ttgggtacta tcttatttgg aatagagtaa tttctttatt
    45661 atttaaatat ttcaaaaatt ggtaagagaa gagcattgta taaactccgg atatatgatt
    45721 gttaatgata aaaatttttc gattagatac aaaatgcttg acttggagtc aactcaaagt
    45781 tatataataa gataagtgag ttagaatagc gtgaattcag tgaatgaaat gagaggaggt
    45841 tagcgtgtga atattaaatc tgccagtgat ttgttgggaa tttcagcgga tacgattcgg
    45901 tattatgaac gggttggtct tgtgccaccg attactcgta ctgctactgg gattcgtgat
    45961 tttcaagatc aggatatcga agcgctggaa tttattaagt gttttcgttc ggcgggtgtc
    46021 tctgtagata gtttagttga ctatatgtcg ctctaccaaa agggagatga aacgagagag
    46081 gagaggcttg gtattttaga agaggaaaag caaaaattag aggagcgctt gtctcagcta
    46141 cagacagctt taaatcgttt aaatctcaaa attaaacttt ataaggaagg aaaattttaa
    46201 atgaaatcag cagtatatac aaaggcaggt caggttggac ttgctagcat tgaacgtccg
    46261 caaataatag aagcggatga tgtgattatt cgtgtggttc gtgcgtgcgt ttgtggttca
    46321 gatttatgga ggtaccgtaa tccagaaacg aaagctggac ataaaaatag tggacacgaa
    46381 gcgattggga ttgttgaaga agctggggaa gccattacga cggtgaaacc aggtgatttt
    46441 gtgattgtcc cttttacaca tggatgtggt gagtgtgatg cctgtcttgc tggatttgac
    46501 ggttcttgcg acaatcatat tggcaataat ttggggggtg attttcaggc agaatatatt
    46561 cgcttccact atgcaaactg ggcgctggtt aaaatccctg gtcaaccttc tgattataca
    46621 gaagggatgc tcaagtccct tttgactctt gcagatgtca tgccgacagg ctatcatgca
    46681 gcgcgtgttg caaatgttca aaaaggggac aaggttgttg ttatcggtga tggggctgtt
    46741 ggtcaatgtg ctgtcatcgc ggctaagatg cgtggagcat cacaaattat ccttatgagc
    46801 cgtcatgaag accgtcaaaa gatggctatg gagtcaggtg cgacagctgt tgttgcagaa
    46861 cgtggtcaag aaggaattac caaggtgcgt gaaatcctcg gtggaggagc agatgcagca
    46921 cttgaatgtg ttggtacgga ggctgctata gaacaggcgc taggtgttct tcataatgga
    46981 gggcgtatgg gctttgtagg agtcccacac tataataatc gtgctcttgg ttcgacattt
    47041 atgcaaaata tctctgtagc aggtggggca gcttctgcta caacatacga taagcaattt
    47101 ttactaaaag ccgtccttga tggtgatatc aatccaggtc gcgtctttac ttcaagttat
    47161 aaactggaag atatcgacca agcctacaaa gatatggatg aacgtaagac cattaagtct
    47221 atgattataa tcgaataaaa aacgaatagg agttctaaaa ctcctattcg ttttttatgt
    47281 tatcctattc ttgatttagg gtactttctc ttaatgtcag tctggttccc agcatggtca
    47341 ggctagggat tttccgaccg tggaggactt ccttgttaag aatatccata cctgctcggc
    47401 ccatttcttc agtataaact gtaatactag agaggggagg atagacctgt ttggtcagac
    47461 tagtgtcgtt aaaggaaatg aggctgacgc gatctggcag gttgattcca gcttcttgga
    47521 gggcacggag ggcaccgata gctaaactat cgctggctgc gaaaaatgct ggcggaagtt
    47581 ggtctcccaa gctctgaatg gcctccttca tcaagtcata gccagactgg gcagtaaagt
    47641 ttccttgaaa gatcagttca tcatgataga ttccttttgc ttgactgtag tttctgaaat
    47701 tttccagccg cttatcctca atgatttctt cttggtctgt tgtttcttca aggcctgtta
    47761 gaatcccgat acggtccatt ccttgactga ggaaataatc gacaacctgt ttcatagcag
    47821 tgtaaaaatc cgtgataata caggtatgtc ccagggaaag tgtatcgctg tctagaaata
    47881 caagaggctt ttggtattct tcaaaggcag aaatctgagc tcgactaaac tttccgatgc
    47941 agagaatccc aatcacttcc tcgcttaggg taaaagggtg gtcattaaaa tagcgcaaga
    48001 tatcgtagtc caactcttgg gctctttttt ctattcctag gcgaatctgg tagtagtaga
    48061 ggtcgtctag ctccccttgt tcgctgaccc attgaataat ggcaatcttt tgcttgggtt
    48121 tgtgggactc gcctgtcttg aggtgcttgg tgtagcccag ctcttcagca acggttaaaa
    48181 tacggtgtct ggtttcttct gtaacagata ggctctggtc gcggttgagg acacgggata
    48241 cggtcgcgat tgagacagag gctagctgtg caatgtcttt taaggtagcc ataaatcctc
    48301 cttgattagg ttagtatatc atatttttct tctttttact gatattttag taaaatttta
    48361 gtaaaaagga ttgaccttgg gaaattcctt ggatacaata gaaagaaaac gattacacgt
    48421 taagatggct taacggacag tcaaaggaga attcatatgg cacaacatct tactactgaa
    48481 gtccttcgca aagactttct tgctgttttt ggtcaagaag cagaccaaac cttcttttca
    48541 ccaggccgta ttaatttgat tggtgaacac acagactaca acggtgggca cgtttttcct
    48601 gctgctattt ccttgggaac ttacggtgca gctcgtaagc gtgacgacca agtcttgcgt
    48661 ttctactcag ctaactttga ggacaagggc attatcgaag tgcctctcgc tgacctcaag
    48721 tttgaaaaag agcacaactg gaccaattat ccaaaagggg ttcttcattt cttgcaagaa
    48781 gctgggcacg tgattgacaa aggttttgat ttttatgttt atgggaatat cccaaatggt
    48841 gctggcttgt cttcttcagc atccttggag ctcttgacag gagtcgtggc agagcatctc
    48901 tttgatttaa aactagaccg tttggatttg gttaaaatcg gaaaacaaac agaaaacaac
    48961 tttatcggag tcaactctgg tatcatggac cagtttgcta ttggtatggg ggctgaccaa
    49021 cgtgctattt acttagatac caatacttta gaatacgact tggtgccact tgatttgaag
    49081 gacaatgtcg ttgttatcat gaacaccaac aaacgccgtg aattggcgga ctctaaatac
    49141 aatgaacgtc gtgctgagtg tgaaaaagca gtggaagaat tgcaagttgc cttggatatt
    49201 cagaccctgg gtgaattgga cgagtgggcc gttgaccaat atagctattt gattaaagat
    49261 gaaaatcgtt tgaaacgtgc tcgccatgct gtgcttgaaa accaacgtac ccttaaagct
    49321 caagcagccc ttcaagcagg tgatttggaa acatttggtc gtttgatgaa tgcgtcacac
    49381 gtttctctgg agcatgatta tgaagtaact ggtttggaat tggatactct tgttcacaca
    49441 gcttgggcac aagaaggagt tctcggtgct cgtatgacag gggctggttt tggtggctgt
    49501 gccattgcct tggttcaaaa agatactgtt gaggccttta aggaagctgt aggcaaacac
    49561 tacgaggaag tagttggata cgctccaagc ttctatatcg ctgaagttgc aggtggcact
    49621 cgcgtccttg actagtcaaa aggaggctct atagtgatct tagtagataa atttgtaaca
    49681 catgtcattt ctgaaagttc atttgaggaa atggatcgaa tctacctgac caaccgtgtt
    49741 ttggcacgag tgggagaagg tgttttggaa gttgagacca atctggataa attgattgac
    49801 ctcaaggacc agctagttga ggaagccgtt cgattagaga tgattgagga tagtcagact
    49861 gcgcgtgaaa tccttggtac tgaactgatg gacttggtga ctccttatcc gagtcaggtc
    49921 aatcgtgact tctgggaagc ctatgtccac tctcctgagc aagcgataga ggatttttat
    49981 caactcagtc agaaaaatga ttacatcaaa ctcaaggcca ttgctaaaaa tatcgcttat
    50041 cgtgttccat ctgattatgg agaacttgaa attaccatca atctctctaa gcctgaaaag
    50101 gatccgaaag agattgcggt agccaagttg gtgcaagcta gtaattatcc tcagtgtcaa
    50161 ctttgtttag agaatgaggg ttaccatggt cgggtcaacc acccagctcg cagcaaccac
    50221 cggattatcc gttttgaaat ggttggtcag gaatgggggt tccagtattc gccctatgct
    50281 tactttaatg agcattgtat ctttttagat ggccagcatc gtcccatggc cattagtcgt
    50341 cagagttttg aacgtctgtt ggctatcgta gagcagtttc caggatattt tgctggatct
    50401 aatgccgacc tgccgattgt ggggggctct attctaactc atgatcatta tcagggaggc
    50461 cgtcacgtat ttcctatgga attggctccc ttgcaaaaga ccttccgatt tgctggtttt
    50521 gagcaggtca aggctggaat tatcaagtgg ccaatgtctg tcctacgctt gacttcggat
    50581 tccaaagagg atttgattaa cttagctgat aagattttcc aggaatggcg tcagtattca
    50641 gattctagtg tgcagatttt agcagagaca gacgggacac cgcatcacac catcacacca
    50701 atagcgcgta agcgtgatgg acagtttgag ttggacttgg tcttgcgaga caatcagact
    50761 tcagcagagc atcctgatgg catctatcat ccccacaagg atgtccaaca tatcaagaag
    50821 gaaaatatcg gcttgattga ggtcatgggc ttggcaatct tgccaccacg tctgaaagaa
    50881 gaagtagagc aagtcgctag ctatcttgta ggagaagctg ttacagttgc cgattatcat
    50941 caggagtggg cagaccaact caaatcccaa catccagacc taacggataa agaaaaagcc
    51001 cttgcaatcg tcaaggactc tgtgggtgct atctttgtgc gtgtacttga ggatgcagga
    51061 gtctacaagc agacagaaca agggcagaca gcctttatgc gctttgtgga acaggtcgga
    51121 attttactag actaggagct ttctccttgc acagtcctat aaaaagtagt atcatagtgt
    51181 cgtttgaaat atcaggagga aacgatgaaa gactttcatt ttgacgctat atctgccttt
    51241 gaaagttacg aaattgaaaa aatgagagat ggtcacgttg tggtgacgac caaagtagtg
    51301 aactcatcgc tcaactacta tggcaatgcc catggtggct atctattcac gctatgtgac
    51361 caaatcagtg gtttggtggt tatctcgctg ggacttgatg gggtgacact ccaatcctct
    51421 atcaactacc ttaaggcagg aaaactcgac gatgtattga ccattaaagg agaatgtgtc
    51481 catcaaggtc gtacaacctg tgtgatggat gtggatatca ccaatcaaga gggcagaaat
    51541 gtctgtaagg caacctttac catgtttgtc acaggccaaa ggtctgagga aagacgggta
    51601 agtatataaa gaaaggtgag tgggataaat ttatctcact catttttaat ttatgagata
    51661 tgttagaagg aaatataaaa gagagtgatg aaatacaaat gtaataggta catatatgtg
    51721 gtatactagt tatagtagat tttaattgct tatatcgagt gagttctcat attagtgagg
    51781 aatttttaaa tggaattaca ctttaattta gaattagtag aaacctataa aagtaatagc
    51841 caaaaggcac gtatcttaac ggaggattgg gtttatcgtc agtcttattg ccctaattgt
    51901 gggaacaatc ccttaaatca ttttgaaaat aatcggcctg tagcagattt ttactgtaat
    51961 cattgtagtg aggagtttga actaaagagc aaaaaaggaa atttttcatc aacaatcaat
    52021 gatggtgctt atgcaacgat gatgaagcgt gtgcaggcag ataataatcc taatttcttt
    52081 tttttaactt acacaaaaaa ttttgaggta aataactttc ttgtccttcc gaagcaattt
    52141 gttacaccga aatcgattat tcaaagaaaa ccacttgcac caactgctag acgagcaggt
    52201 tggattggtt gtaacattga tttatcacaa gtaccttcta aaggaaggat atttcttgtg
    52261 caagatggac aagttagaga tccagaaaaa gttacaaaag aatttaagca aggtttattt
    52321 ttaaggaaga gctctctgtc atcaagaggt tggacaatag aaattctaaa ttgtatagat
    52381 aagatagagg gttcagaatt tacccttgaa gatatgtatc gttttgaaag tgacctaaaa
    52441 aatatctttg ttaagaacaa tcatatcaaa gaaaagatta ggcaacagct tcaaatatta
    52501 agagacaaag aaataataga atttaaaggt agaggaaagt atcggaaatt atgaaaacga
    52561 aacaacttgt tgcatcagaa gaggtgtatg atttcttaaa agtcatctgg cctgattatg
    52621 aaactgaaag ccgttacgat aacctaagtt taatcgtctg taccttatca gatcccgatt
    52681 gtgtgagatg gttatctgaa aatatgaaat ttggtgacga aaaacaacta gctttgatga
    52741 aggaaaaata tgggtgggaa gtaggagata aattgccaga gtggctacat agctcctatc
    52801 atagattatt gttaataggt gaattattgg aaagcaatct aaaactgaaa aagtatacag
    52861 tagaaattac agaaacttta tcacgtttag taagtataga ggctgaaaat ccagatgaag
    52921 ccgaacgact tgtaagagaa aagtataaga gttgtgaaat tgttcttgat gcagatgatt
    52981 ttcaggacta tgacactagc atatatgaat aggtagatgt ttttattttg tcacacaaaa
    53041 aagaggctcg cacctctttt tcttatttct ttttatgatt taatacggca ttgaggacaa
    53101 tagcgagtag gctggctacg acgattccgt ttgagaagaa catttggaag gctgtcggca
    53161 tgctgacaaa gagattactg ttgttgagac cgacacctgc agcgattgaa acagctgcga
    53221 taaggaagtt gtgttcattg ttagcaaagt caactcgggc gaggatttgc atcccttgaa
    53281 tagatacaaa accaaacatc accagcatgg caccgccgag gacggagctt ggaatgattt
    53341 gggcaagggc accaaactta ggaagcagtc caaggagaac caggaaacca gctgcgtagt
    53401 agattggcag gcgttttttg atgcctgaca atttaaccaa accaacgttt tgtgaaaatc
    53461 cggtgtaagg gaaggtgtta aagattcctc cgagaagtac cgccaaacct tctgcgcggt
    53521 aaccgttgcg aaggcgcgtg ctgtcgattg gatcttttgt gatatcagac aaggctagat
    53581 aaacaccagt tgactcaacc atagacaccg ttgcgatgat acacatcatg acaatagatg
    53641 agatttcaaa ggttggcatc ccaaagtaga gtggagttgg gacatggaca agtggagcta
    53701 ccgcaacagg agagaagtcc accaagccca tagtagcagc aatggcagtt ccaacaacca
    53761 gaccaatcaa aatagagata gacttgataa atcctttggt aaagatgttg atcaagagga
    53821 taatcagaac agtaatagct gcaagcaaga gactttgacc agttggctct ggaacgttat
    53881 ttcccatatt tccaatagcg acagggatca aggttaaacc aatcgtggta ataacagatc
    53941 ctgttacgat agatgggaag agattggcta cttttgagaa gatgcctgaa acaagaacca
    54001 cgtaaatccc agatgcgata agggcaccaa acatagcgcc attaccatgg ctttgcccaa
    54061 tcataatcaa gggagcgacc gactggaatg caactccaag aacgactggg agtccaatcc
    54121 caaagtattt gttgagttgg agttggagga aggttgccac cccacacatg aagatatctg
    54181 tagaaatcag gtaggtcaac tgctcagctg aatagccaag ggctgtcgca atcatgatgg
    54241 gaaccaggat agatcctgag tacatggcta gtaagtgctg caagcccaga acggctgctt
    54301 gcgagtgttt ttcttgagtt tgcattagag atctgcctcc ttaaatacga cctgaccatt
    54361 ttcaaaacga tccaagcgag caagtgatag gacagggtag cctgcttttt caagcaaatc
    54421 acgaccatct tggaaggatt tctcaatcac gataccgata gcttggactg tggcaccggc
    54481 ctgttcgatg atttgaatca agcctttagc agcttggcca ttagcaagga aatcgtcgat
    54541 aatcaaaacc ttgtcctctg gtgagaggaa ttttccagcg atagaaacag tgctggtcac
    54601 ctgcttggta aaggagtaga cttgagcagt taagatgcct tcgttcatgg tgatgttctt
    54661 agcttttttg gcgaaaatca tgggaacgtt taaggcttca gctgtaaaaa cggctggggc
    54721 aatacccgac gcttcaatgg ttacgacctt ggtaatgcca gtagcagcaa atttttccgc
    54781 aaaaacctta ccaatctctc gcatcaagct aaagtcaact tggtgggtta aaaaggaatc
    54841 taccttgagg atgttatcac ccaagatatg cccatccttg aggatgcgct cttctaataa
    54901 tttcataaga cctcctaaag tctaaaagtt aatttacttg ttgtttaaat atttctatag
    54961 tgatcccttt tgctaatact atatatttga taaaactatt acgagcgaag cgagtcttat
    55021 caaatatttc ccgttgtagt ggtatcatag acaataatct tgttattgtc tatgacggga
    55081 tttttgagag taaaatagtt cggggaacta ttttagccta agcctagaaa tgaaagagct
    55141 aggggctcaa aaattaggga tgaaattccc tggattcctg aaattattca caggataatt
    55201 tcacctcccg tccgcactaa ttaagggaaa tattaaaaat attcaaaaaa gacctactta
    55261 atctctaagt aagtccccta aatagacatg gcaaaaacgg ccatatctca ctgctgactt
    55321 acttattgtt aggtgttccg gcaccttgta gaaacgtcgt gccaattcac gacataaaca
    55381 agtaaaacga tattcaattt taaataggct tgagccaatg tttttatttt acactaaata
    55441 actttagaaa tcaactattt tgttagtgtt ttggtttaaa aagcgaacaa aaataagaga
    55501 gggtgaacaa aaactccatt gtaagctaac atttatacta aatgaaaatc aaagagcaaa
    55561 ctaggaagct atccacaacc tcaaaacact gttttgaggt tgtggataga attgacagag
    55621 tcagtatcat atacctacgg taaggcgacg ttgacgtggc ttgaagagat tttcgaagag
    55681 tattagaaga tttttccatc ataaaaggca tactatcaag tttttagaca cctgacaata
    55741 tgcctttttc taactttaaa gacttttccc aatttttatt attctactcg ctaaatctta
    55801 aaaaatagcc atctggatcc aaaactgcaa atttatgagg atagatatag ggatcactga
    55861 cacgaaactt tcttttggtc aagagacgat aaataggata gtttgcctcc atcacttttt
    55921 gatagagttt tggaacatcc tttatgccaa aggagagatt gactccacga ccaaaggggt
    55981 aggtcagttc agctagttga tcctttgttc cctcctctaa cattagttga cactcttcaa
    56041 gagaaagaga aagttttctt ctggacgtta gtattcaatc ctaaaaccca gtaaaccaca
    56101 gtagaaggac cgggactgtt cgatattcga tacaagaaac tcgggaatga ccgcattgta
    56161 gtccatatag aaaatcctta caagtcaatt tccaagacaa tcggtgtatg gtcttggcga
    56221 gcacctgagt caatcatatc agatttagtg accttgtcag cgatacggtt acttgtgagc
    56281 cagtagtcga ttctccagcc tgtattgttg attttagaag ttttgctgcg ttgtgcccac
    56341 caagtgtagc gttcaggaac atcgccatga acatggcgga aggtgtctgt aaatccagtt
    56401 gccaaaaggt tggtaaatcc agcacgttcc tcgtcagtaa atccaggtga acggcggttg
    56461 ctagcaggat ttgcaaggtc gatttcattg tgggctacgt tgtagtcacc ggtcgcaagg
    56521 actggttttt ctttgtctag ttcagccaaa tactcagcat atttaacatc ccagacttgg
    56581 cgttcttcca agcgtttgag accgtcacca gcgtttggag tgtaaacttg ggttacgaaa
    56641 aatgcatcaa attctagagt gatgatacgg ccttccaagt ccatggtaga aggggcaccg
    56701 atttctggaa aactgatcgt aggcgtaagt tctttcttat aaaggaacat ggttccagca
    56761 tagcctttac gggcaggctc ttgggaagag cgccatgtgt tttcgtagcc tgggaagagt
    56821 tcttctaaaa tttccacgtg tttctttgta ggtcctttgg cagaaagctt ggtttcttgg
    56881 atagcaatga tatcagcatt ttcagcgacc aaggtttgta ggacttcttg ggacaatttg
    56941 gcacgagctg agtcactagt tagggcagcg tttagggaat caatattcca tgagataagt
    57001 ttcataaagt tacctttttc attcagatta tagattttat tataccaaaa aaagatctat
    57061 ttccccaacg tatggtttga aaaattactc tctttcgttt ataattaaga atgattttat
    57121 gaaagggagt gaaaatatat gaaattctac tcttatgact atgtactcag ccaaatcggt
    57181 cagcaaaatg gtatcatggt tggctttggg attgttctat tagctgtgac agtttttttt
    57241 gctttcaagg cataccatga taaaaaggga accgaatttc gtgagttggt catgatttca
    57301 gctctggcct tatttagctc tgcttttggt cagcatcacg acttatcaaa acaatcaagt
    57361 ttctaacaat aaatttcaaa cttcacttca tttcatcgag gttgtttcca aagatttggg
    57421 agtagacaag tcagaagtct atgttaatac ttccacaaac acagatggcg cacttatcaa
    57481 ggtgggagat cgctattatc gtgccctaaa cggaagtgag ccagacaagt acctgttaga
    57541 gaaagtcgaa ttgtataaga cagacgcaat tgaactggtg gatgtgaaca aatgacactt
    57601 aattatatcg aaattttaat caaactggtc ttgactctca aatggctcaa caacaatgtt
    57661 cactttgtga aacgtttgat tgatggtaag ccaactctcc ttatcaaaaa tgggaatatt
    57721 gacccagaag cctgtcgttc agttggtttg tctgcatcgg atgtagccct caaacttcgt
    57781 agccaaggga ttttccagat gaagcaagtc aaacgagctg tgcaagagca aaatgggcaa
    57841 cttatcgttg tgcaaatggg agatgaaaat cctaagtatc cagttgtgac tgacggtgtg
    57901 attcaagtag atgtcttgga atcgattggt cgtagcgaag agtggttgct tgataacctc
    57961 agtaaacaag ggcatgacaa tgtagccaat atctttattg ctgaatatga caagggtgct
    58021 gttacagtcg taacttatga aaaagaaaaa cctggggtct tgtactcttc gaaaatctct
    58081 tcaaaccgcg tcaacgtcgc cttgccgtat gtaggttact gacttcgtca gttctatcta
    58141 caacctcaaa gcagtgcttt gagcagcctg cggctagttt cctagtttgc tctttgattt
    58201 tcattgagta ttggcctcag gtttccattt gcaatcagaa agggatttta tgtccattat
    58261 tcaaaaactt tggtggtttt tcaagttaga aaaacgccgt tatctagtcg gaattgtggc
    58321 cctggtcttg gtttccgtcc tcaatctcat tcctcctatg gttatggggc gggttattga
    58381 tgccatcaca tcggggcaat taacccagca ggacctcctt cttagcctat tttacttgct
    58441 acttgcagcc tttggtatgt actatttgcg ctatgtgtgg cgtatgtata tccttgggac
    58501 ctcttattgc ttgggacaga tcatgcggtc tcgcttgttt aagcatttca caaaaatgtc
    58561 gtcagccttt tatcaaacct atcggacggg tgatctgatg gcacacgcaa ccaatgatat
    58621 caatgccttg actcgtttag caggtggcgg tgtcatgtct gcggtggatg cctctatcac
    58681 ggctctggtg actttgttga ccatgctctt tagcatctca tggcagatga ctcttgttgc
    58741 cattctcccc ctacctttca tggcctatgc gactagtcgc ctagggagaa agactcataa
    58801 ggcctttggc gaatcccaag ctgctttttc tgaactcaat aacaaggtac aggagtccgt
    58861 atcaggtatc aaagtgacca agtctttcgg ttatcaggca gacgagttga agtcttttca
    58921 ggcagtcaat gaattaacct tccaaaagaa cctgcaaacc atgaaatatg atagtctctt
    58981 tgaccctatg gttctcttgt ttgttggttc gtcctatgtt ttaacgcttt tggttggctc
    59041 cttggtggtt caggaagggc agattacagt tgggaatcta gtcaccttta tcagctattt
    59101 ggatatgctg gtctggcctc ttatggccat cggcttcctc tttaatacta ctcagcgagg
    59161 gaaggtttct taccagcgga ttgaaaatct tttgtctcag gaatctcctg tacaagaccc
    59221 ggagtttcct ctggatggta ttgaaaatgg gcgtttggag tatgccattg acagctttgc
    59281 ttttgaaaat gaggaaacac tgacggatat tcactttagt ttggcaaaag ggcaaacact
    59341 gggcttggtt gggcagacag gctctgggaa aacgtcctta atcaagctcc tcttgcgtga
    59401 atacgatgtg gataagggcg ccatttatct aaacggtcac gatattcggg actatcgtct
    59461 gacagacctt cgcagtctca tgggctatgt tcctcaggac cagtttcttt ttgcgacttc
    59521 aatcctagac aatatccgct ttggcaatcc taacttgccc ctttcagcgg tcgaggaagc
    59581 tactaagcta gcccgagttt accaagatat tgtagacatg cctcaaggat ttgatacgct
    59641 gattggtgaa aaaggagtca gtctttctgg tggtcaaaag caacggttgg ctatgagtcg
    59701 ggctatgatt ttagaccctg atatcttgat tttggatgat tccttatccg ccgtagatgc
    59761 caagacagag tatgcgatta tcgacaacct caaggagacg cgaaaggaca agacaaccat
    59821 tatcactgcc catcgcctga gtgcagttgt ccatgcagat ttgattttag tcctgcaaaa
    59881 tggtcaaatt atcgaacgag gcaggcacga agacttgcta gctttggatg gctggtatgc
    59941 ccaaacctac cagtctcagc agctggaaat gaagggagaa gaagatgcag aataaacaag
    60001 aacaatggac tgtattgaag cgcttgatgt cctatctcaa gccttatgga ctccttacct
    60061 ttttggcact cagttttctc ctagcgacga cggtcattaa aagtgtcatt ccccttgtgg
    60121 cttcccactt tatcgaccag tatctcagca atcttaacca actagccgtg accgttttgc
    60181 tggtctacta tggtctctac atcctacaaa ctgtagttca gtatgtcggc aatcttctct
    60241 ttgcgcgcgt gtcttacagt attgttaggg atattcgtcg ggatgccttt gccaatatgg
    60301 agaaactggg catgtcttac tttgacaaga cgccagcagg ttctatcgtt tctcgtttga
    60361 ccaacgatac cgagacgatt agtgatatgt tttctgggat tttatccagc tttatctcag
    60421 cagtttttat ctttctgaca accctttata ccatgttggt gctggatttt cgtttgacgg
    60481 ctttagtctt gctctttctc cccttgattt tccttttggt caatctctat cgaaaaaagt
    60541 cagtgaaaat catcgagaaa accagaagtc tcttgtcaga tatcaatagt aagctggcag
    60601 agaatatcga gggaatcagg attattcagg cttttaatca agagaagcgc ctgcaggcag
    60661 aatttgatga aatcaaccaa gagcacttgg cctatgccaa ccgttctgta gccttggatg
    60721 ccctcttttt gagacctgcc atgagtttgt tgaaacttct aggttatgct gtcttgatga
    60781 cctattttgg ctatcgtggt ctttctatcg ggataacggc cgggaccatg tatgctttta
    60841 tccagtacat caaccgcctc tttgaccctt tgattgaggt gacgcaaaac ttttcaacac
    60901 tgcaaacgtc tatggtttct gcaggccgtg tctttgcctt aatcgatgag aggacctatg
    60961 agccccttca agaaaatggg caagccaaag tcaaagaagg caatatccgt tttgaacatg
    61021 tgtgtttctc gtatgacggt aaacatccga ttctggatga catttctttc tctgttaata
    61081 agggtgaaac cattgccttt gtaggtcata caggttcagg gaaatcgtct attatcaatg
    61141 tcctcatgcg cttttatgaa ttccagtcag ggagagttct cttggatgat gtggatatca
    61201 gggatttcag tcaagaagag ctgagaaaaa acatcggttt ggttttacag gaacccttcc
    61261 tctatcatgg aactattaag tccaatatcg ccatgtacca agaaatcagt gatgagcagg
    61321 ttcaggctgc ggcagccttt gtggatgcag attcctttat tcaagaactt cctcaggggt
    61381 acgactcccc tgtttccgag cgtggttcga gcttctctac tgggcagcgc cagcttcttg
    61441 cctttgctag aacagtcgcc agccagccta aaatcctgat tttggatgaa gcgacagcca
    61501 atattgactc tgaaacagaa agtttggttc aagcttctct ggcgaagatg agacagggcc
    61561 gaacaactat tgctatcgct caccgccttt ctactattca agacgccaac tgcatctatg
    61621 tcttggataa gggacgcatt atcgagagtg gaacccatga ggaactcttg actctgggag
    61681 gaacctatca caagatgtat agtttgcagg caggggccat ggcctatact ctttgaaaat
    61741 ctctttaaac catgtcagct ttatctgcaa tctcaaagct gtactttgat tttcattgag
    61801 tactagaagg aaatccttca aattacagat ttctttcacc gccttttcca ttttgtggta
    61861 taatgaaaaa tgttgacaaa tagtataata aaaacaaagg agaacagcat gctgaaatgg
    61921 gaagacttgc ctgtggaaat gaaatcaagc gaggttgagt cttactacca gcttgtctct
    61981 aaaaggaagg gttcgctgat tttcaagcgt tgcttggact gggttttggc cttggtctta
    62041 ctggttctaa cttctcccat ctttctcatc ttgagcattt ggatcaagtt ggatagcaag
    62101 gggccagtga tttacaagca agagcgtgtg acccagtaca accgtcggtt caagatttgg
    62161 aagttccgta ccatggtgac ggatgcggat aaaaaaggaa gtctggtgac ttctgctaac
    62221 gatagccgta ttaccaaggt tggaaatttc atccgacgtg tccgtttgga cgaactgcct
    62281 cagttggtca atgtccttaa aggtgagatg tcctttgtcg gtacacgacc tgaagtgcca
    62341 cgttatacag agcagtatag ccctgaaatg atggcaacct tgctcttgca agcaggaatt
    62401 acctctccag ccagcatcaa ctacaaggat gaggacacca tcatcagtca aatgacggag
    62461 aaaggtctgt cagttgatca ggcctatgtg gagcatgttc ttcctgaaaa gatgcgctat
    62521 aacctcgcct atctccgaga gtttagtttc tttggggaca tcaaaatcat gtttcaaacc
    62581 gtgtttgagg tactaaaata aagtagtcat aagaaaatga gtacagataa aaggagcaaa
    62641 tcaatgccaa attacaatat tccattttca ccgcctgata tcacagaagc agaaattgct
    62701 gaagtagcgg ataccctgcg ttctggttgg atcacaacag gtcctaaaac aaaagaactg
    62761 gagcgccgct tgtctcttta cacacagaca cctaagactg tttgtctcaa ctctgcgaca
    62821 gccgctctgg agttgatttt acgcgttttg gaagtgggac ctggtgatga agtcatcgtt
    62881 ccagccatga cctatacggc ttcatgtagt gtcattacgc acgtgggagc aacccctgtc
    62941 atggtggata tccaagcaga tacgtttgag atggactatg acctgcttga gcaagctatc
    63001 actgagaaaa ctaaggtgat tatcccagta gagctcgcag ggattgtttg cgattatgac
    63061 cgtttgttcc aagtcgtgga gaaaaaacgt gacttcttta ccgcttcaag caagtggcaa
    63121 aaggccttta accgtattgt cattgtctct gatagtgccc acgctttggg atctacttat
    63181 aaaggacaac cttctggttc tatcgctgat tttacttcct tctcattcca tgctgttaag
    63241 aactttacaa cggcagaagg tggaagtgcg acttggaaag ccaatccagt gattgatgac
    63301 gaagagatgt acaaggaatt ccaaatcctt tcccttcacg ggcaaactaa ggatgctctt
    63361 gccaagatgc aactggggtc atgggaatac gatatcgtta caccagccta taagtgcaac
    63421 atgaccgata tcatggcttc acttggtttg gtacaattgg accgctatcc aagtttgttg
    63481 caacgccgta aggacattgt ggaccgctat gatagtggtt ttgcaggttc tcgcatccat
    63541 cctttggcac acaagactga aactgtcgaa tcttcacgcc acctctacat cacccgtgta
    63601 gaaggagcaa gcctagaaga acgcaacctc atcatccaag aattggctaa agcaggaatt
    63661 gcaagtaatg ttcactacaa accgcttcct ctcttgacag cctataagaa tcttggattt
    63721 gatatgacga actatcctaa ggcctatgcc ttctttgaga atgaaattac cctccctctt
    63781 catactaaat taagcgatga agaagtagac tatatcattg agactttcaa aacagtttct
    63841 gaaaaagtgc taactttatc aaaaaaatga caaactacag tcaagcgaaa gtgatcctgt
    63901 ccctaaaaag tctaattgag tgtaaaaact gttgttttca attgataata gtttacacct
    63961 gtagttgagg cctctttctc ctcagagaga gaatttttat aggattttcc tttcttgtgg
    64021 gagtcccgtg gtttgaaata agatgtgagc aatttggtat agcatttaga atccttacta
    64081 gacatcattt agaaaatcta gtgtcttgtt ctagttttca attcacccta ttttttgaaa
    64141 gacgtgagtt tccatgagtg agattgtgga aactagcgtc ttttttttgt tttcagaata
    64201 ttgttcaaag ttttgtgcct gtctttcatg ttctagtcat tcttttgcat gatagaattt
    64261 atagcatgtt gatattataa taacgcaaat atcccatatg tttagtgatg cttgctatac
    64321 atcattagat ctcctgcgag acaatctata aaacacttgt ctacgattac ctatatgccc
    64381 tattccagta ttttagaagc actgcatcta tttttatcga ggttaaatct agcttttata
    64441 gaaggtctat ttaagaaata tattgtagtg ttttagtttc aatccgccat atgagcgata
    64501 ttcaggtaaa tatccctggc gaatgcttgt atgacaaggt atttgttctt tcatttataa
    64561 tttacaacat atcaacaaat ttaaatatag taaatgggat attttatatt caagctaaga
    64621 aagatagcat cacttttgaa tggaaggcta aagagcaaac taggaagttg gccatagata
    64681 gctcaaaacc ctgctttgag gttgtagata tagtaaaatg aaacaagaat aggacaaatt
    64741 gatcgggaca gttaaatcga tttctaacaa tgttttagaa gtagaggtgt actattatag
    64801 tttcagtcta ctatagaact gaccaagtca gtaacctaga cttagggcaa ggcggcactg
    64861 acctagtttg aagagatttc cgaagagtat aaattttaat attttcttgt gttattcctt
    64921 gacaattcaa tttggaaaat atatgataaa gataatgaca gcggtgtcat tctatctatt
    64981 ttaagaaaag taataatcaa ttgttaaaaa tagtaaaaaa attggaggtt ctgatgaaat
    65041 attttgttcc taatgaggta ttcagtattc gtaaattaaa ggtggggact tgctcggtac
    65101 tattggcaat ttcaattttg ggaagccaag gtattttatc ggatgaagtt gttactagtt
    65161 cttcaccgat ggctacaaaa gagtcttcta atgcaattac taatgattta gataattcac
    65221 caactgttaa tcagaatcgt tctgctgaaa tgattgcctc taattcaacc actaatggtt
    65281 tagataattc gttaagtgtt aatagtatca gctctaatgg tactattcgt tccaattcac
    65341 aattagacaa cagaacagtt gaatctacag taacatctac taatgaaaat aagagttata
    65401 aggaagatgt tataagtgac agaattatca aaaaagaatt tgaagatact gctttaagtg
    65461 taaaagatta tggtgcggta ggtgatggga ttcatgatga tcgacaagca attcaagatg
    65521 caatagatgc tgcagctcaa gggctaggtg gaggaaatgt atattttcct gaaggaactt
    65581 atttagtaaa agaaattgtt tttttaaaaa gtcatacaca cttagaattg aatgagaaag
    65641 ctacaattct aaatggtata aatattaaga atcacccttc cattgttttt atgacaggtt
    65701 tatttacgga tgatggtgcg caagtagaat ggggcccaac agaagatatt agttattctg
    65761 gtggtacgat tgatatgaac ggtgctttga atgaagaagg aactaaagca aaaaatctac
    65821 cacttataaa ttcttcaggt gcatttgcta ttgggaattc aaataacgta actataaaaa
    65881 atgtaacatt caaggatagt tatcaagggc atgctattca aattgcaggt tcgaaaaatg
    65941 tattagttga taattctcgt tttcttgggc aagccttacc caaaacgatg aaggatgggc
    66001 aaatcataag taaggagagc attcagattg aaccattaac tagaaaaggt tttccttatg
    66061 ccttgaatga tgatgggaaa aaatctgaaa atgtgactat tcaaaattcc tattttggca
    66121 aaagtgataa atctggggaa ttagtaacag caattggcac acactatcaa acattgtcga
    66181 cacagaaccc ctctaatatt aaaattttaa ataatcattt tgataacatg atgtatgcag
    66241 gtgtacgttt tacaggattc actgatgtat taatcaaagg aaatcgcttt gataagaaag
    66301 ttaaaggaga gagtgtacat tatcgagaaa gcggagcagc tttagtaaat gcttatagct
    66361 ataaaaacac taaagaccta ttagatttaa ataaacaggt ggttatcgcc gaaaatatat
    66421 ttaatattgc cgatcctaaa acaaaagcga tacgagttgc aaaagatagt gcagaatatt
    66481 taggaaaagt atcagatatt actgtaacaa aaaatgtaat taataataat tctaaggaaa
    66541 cagaacaacc aaatattgaa ttattacgag ttagtgataa tttagtagtg tcagagaata
    66601 gtatattcgg tggtaaagaa ggaattgtta ttgaggattc aaagggtaaa ataaccgttt
    66661 taaataacca attttataat ttatccggta agtatatatc attcatcaaa tctaatgcaa
    66721 acgggaaaga acctgttata cgtgatagcg atggtaattt caatattgta acggagaatg
    66781 ggctttacaa aattgtaaca aataatttaa gtgataaaaa cgaaaaagaa aaaaacaaag
    66841 aggaaaaaca atctaattca aataatgtaa ttgatagtaa ccagaagaac ggagagttta
    66901 actcaagtaa agataataga caaatgaatg acaagatcga caataaacaa gataataaga
    66961 cagaagaagt aaactataaa atagttggag atggcagaga aactgaaaat catattaata
    67021 aatctaaaga aatagtagat gtaaaacaaa aattaccaaa gactggttcg aacaagatta
    67081 tggaactatt cttaacagtg acaggaattg gtttactttt gacactaaaa gggttgaagt
    67141 attatggtaa agataaataa aatttgttcg atacaaggaa gttccgtaga aaatgaggat
    67201 attgtaggtt cacaaaatca gtatttttgg attattggtg gagctacaga tttatataat
    67261 tctaaagagg agataggtta ttcagtctca gaagttgtac atattttatc agaaagtttg
    67321 tcggttaatt gtaaagaatc aaaaactctt aaacaaatat ttgaaactgc tttactcgag
    67381 gttaaagatg aaatcggttt aaactcatat gaattaacag agtataataa aatgaaataa
    67441 taataggaca aatcaatcag gacagtcaaa tcgatttcta acaatgtttt agaagtagag
    67501 gtgtactatt ctagtttcaa tatactatat tatcgcttac caacatttgc ttttatattt
    67561 gctaaacttt cagaaaaaaa gttggagtat atgatgctag gtgactgcgt catgttagta
    67621 aacgaaatgg aaataacgga tcatagagta gataacttat ttgaaaaagg gaaaaatgag
    67681 ataaaagatc caattggtac aaatagtgtt ttaaataaaa aaattatttt acaaaaaatc
    67741 agaaaattat ctaatcaacc gagtgggtac tggataggtt cgttggatga gagattttta
    67801 gaccatgcta ttattaatca aatagatgtt actagtgaac aaattgtttt aatgagcgat
    67861 ggcttttatg aattctatca aaataatcaa aataaaactt ttgaagagtt aattaagatg
    67921 agatttaatt cttctgctat tgatccaatc tatggaaaga aagatgatgc aagtattgta
    67981 gttattgatg tttgatatat tgtttaaaat attaattgtt actattgaac tttgttaaga
    68041 agaggtacct aaatgttaag gttatattta gaaaatgaaa ttatagaatt atcaaataat
    68101 ttagagacca tttgggtatc tgtgcttgat aaatatgaga agttatttga atatttatca
    68161 aatgaagaac gaatagaatt gattaaagaa gatttaatca taaatgagtc agttctaaat
    68221 gttgataaaa aaggatatga gttaatttgt ttacaacatc ccgtttcata tgacttaaga
    68281 agaattatta gtgtaataaa aatatcaact gacattgaac gtattgggga tagaattgtt
    68341 gaaattttaa aaaatctaca gattattcaa aataatgaaa ttttgaagaa aattatttca
    68401 gaaataaaaa tacttcatga agttatcgga ctgcatatga atagggctat atcttgttat
    68461 agagaggaac aatctggatg tttagatatg gttgttatac aaaaacagaa tgagatagaa
    68521 gagcttagta caaatattga aaagaaaata atgaattaca tatttgaaga tgatgggaat
    68581 gtttctgaag taattggtgc tttagatatt attcatcacc ttgataaaat tgctcatact
    68641 acgcaatcaa tttataaatg gataatgtat agaaaatatg ggaacataaa ttagaaagaa
    68701 aaatatatga aaacaattat tgataatttt gttgatagag taattgaata cggaatgtat
    68761 aatgaaattg acaaaatata tgtgaaaaat agagtactag cgttaatagg tgaggaggga
    68821 actgatcgca tttccgatga aaatgacctg aaacaaataa aagattactt agtggaaatc
    68881 gccttaaaaa acggtaaaat taaagattta atcgaggaaa aggaatgttt aggagcagag
    68941 ttaatgaatt tcatagttcc tttacctagt cgattaaatg atattttttg gagttcatat
    69001 gatatatcac ctcaagaagc agttgaagag ttttataagt taagtaaaga tagtgattat
    69061 attaaaactt ctgctattgc taagaatatt gagtttcgag catcaactaa atacggagag
    69121 ctagagatta cgataaattt gtcaaaaccc gaaaaagatc caaaaacaat tgctgctgaa
    69181 aaattagtaa aagccactaa ttatcccaaa tgtttactat gtatggaaaa tgaaggatat
    69241 caggggcgaa taaattatcc agcacgttcg aatcatagaa ttattcgatt gaaacttggt
    69301 gacgaagtat ggggattcca atattctccc tacttatact ttaatgagca tgcgatattt
    69361 ttaaatagtc aacatgtacc aatggctatt acctctaaaa catttgaaca attattggag
    69421 attgttgata ttttgccagg atattttgct ggttcaaatt ctgatcttcc tatctcagga
    69481 ggctccattc ttagtcataa ccactaccag ggagggaaac atattttccc aatggaaaaa
    69541 gcaaaatttg agagtgaatt tcgttttaaa gactttgagg atgttaatgc tggtattgta
    69601 aaatggccaa tgtcagtaat taggttacaa agtgaaaata aaaatcgctt gttagattta
    69661 gctactaaaa ttctaaataa gtggagagaa tattcagatt tagaagtaga catcattgct
    69721 atgactgaag atgtcccaca ccatacggtg actcctattg ctcgtaaagt ggacgggaga
    69781 tatgaattag atattgttct aagagataat catactactg aacagtaccc agatggtgtt
    69841 ttccatcctc atcaagatgt acaacatatt aaaaaggaaa atatcgggtt aatcgaagtg
    69901 atgggacttg cgatattacc acctcgtttg aaaccagagt tagaagaagt tggaaaatat
    69961 cttttaggag aggataacgc aattgcggat tatcatttag aatgggccga ccaattgaaa
    70021 gaaaaatatc ctcgcattaa taaagaagag gttaatagcg tagttcaaca cgaagcagga
    70081 caagtgtttg cgagagttct ggaagatgca ggagtttata agaatacacc gtctgggcat
    70141 gaagcgttta tgagatttgt taagtcggtt ggaattaatt aggaggaaac aaaaatggca
    70201 atattggtaa caggcggagc tggttatatt ggtagccata ccgtagtaga attactaaat
    70261 ttaggaaagg aagtcatcat tgtcgacaac ctttcgaact ctagcatctt ggtgctagac
    70321 cgtattgaag caattacagg aatacgtccc gtgttttacg aattagatgt ttgtgataaa
    70381 ccagcattga gaaaggtatt tgaacaagaa tcgattgatg ctgcaattca ttttgcaggt
    70441 tataaagctg tcggagaatc cgtgcaaaag cctgtgatgt actacaaaaa taatattatg
    70501 agtacattgg cacttgttga agtgatgtca gaatttaatg ttaaaaagat tgtcttttct
    70561 tcaagtgcga ctgtatatgg aattaacaat cagtcacctc taattgagac gatgcaaaca
    70621 agtgcgacaa atccttatgg gtatacgaaa gtgatgcttg agcaaatttt aaaagatgtt
    70681 catgtggcag attcagaatg gagtattgcg ttgcttcgtt atttcaatcc aattggtgct
    70741 catgagtctg gtttgattgg ggaagatccc tcaggacttc ctaacaactt gatgccttat
    70801 attgcacaag tagcggtagg taagctatca gagctaagtg tgttcggaaa tgattatgat
    70861 acgcttgatg gtactggtgt gcgtgattat atccatgtag tagatttagc aataggacat
    70921 ataaaagctt tagaaaaagt atctgaaaaa acagatgttt atatctataa cctaggctcg
    70981 ggagaaggca ctagtgtatt acaacttgta aatacatttg aaagtgttaa taagatccct
    71041 attccttata aaatagttcc aagacgttca ggagacgttg caacttgtta tgcaaatgca
    71101 gacaaagcat ataaggaatt aaattggagg acaacaaaat cgattgaaga catgtgtaga
    71161 gatacatgga attagcaatc aaaaaatccc aatggctata attgatgata ctgtctatat
    71221 gagtgctgta ttttggaaaa attacttaac cttttaatga aatgcatatt taatgaaaga
    71281 taaattaaaa aaaatgtttg acagcgcttg acaaaggaaa cggtttcatt gtataatgta
    71341 aacatagtga caccgatgtc aaatataaaa aagaaggtct ttatatgaaa aacttaacaa
    71401 aaattaagtt caaagaaaat ggggaattta atcatttccc tgggaataca gttgtagcaa
    71461 atctttatac taaacaagat ttgatggaag ttgttgatat tattcaatca cgttatagag
    71521 aattaccatt tatcgataag tttactttaa ctccaaggaa ttctattcac atgactgtaa
    71581 ttgaattgtt gtgccatgaa aatcgtgaaa cggagttttg gagcagtaat cttcctctag
    71641 atacaccttt acaggaaata catgattact ttgctaaaca acttgaaatt tttccattgt
    71701 tggatgaaga aattcatatg cgtataactg aaatgggaaa acaaaacata ctagttgaac
    71761 ctgcagatga agcttctgca aagagattag aagaaattcg tacttatgtc tcagaaaaag
    71821 caggtgtttg tttccctaat catgatagat atcaattcca tatttcaatt gggtatcttc
    71881 ggattcctct aaccgaagag gaggaagaag agtttactaa agtcagagca gaattaactg
    71941 aaattttatt agagaagatt ccaactatta ctgtaaaccg tattgactat actgtatttg
    72001 aagatatgag acaatttgtt ccatatcacg aaaaatttaa ataaaataat aaaaaaggag
    72061 aacttatcat gaaaaaaatg aaagtttggt ctactgtact tgcaacggga gttgctctta
    72121 ctacacttgc tgcttgctct ggaggttcaa attctacgac tgcttcttca tctgaagaaa
    72181 aagctgataa aagtcaagaa ttagttatct attcgaactc agtctcaaat ggtcgtggtg
    72241 attggttaac tgctaaagca aaagaagctg gttttaatat aaaaatggtt gatatcgctg
    72301 gcgctcaatt agcagaccgt gttattgctg agaagaataa tgcagttgca gatatggtat
    72361 ttggaattgg tgctgttgac tcaaataaaa ttagagatca aaaattacta gtacagtaca
    72421 agcctaaatg gttagataaa attgatcaat ctttatcaga taaagataat tattataatc
    72481 ctgtgattgt tcaaccatta gttttaattg gggcgcctga tgtaaaagaa atgcctaaag
    72541 actggacaga gttagctagt aagtataaag gtaaatattc aatttatggt cttcaaggtg
    72601 gtacaggacg ggcaattcta gcaagtatct tagttcgtta ccttgatgaa aaaggagatt
    72661 taggcgtatc agaaaaagga tggggagttg caaaagaata ctttgcaaat gcctatactc
    72721 ttcaaaaagg tgaaagctca gttgttaaag cgttagataa agaaagccca attcaatacg
    72781 gtatgatctg gggttctgga gcgttaatcg gacaaaaaga acaaaatgtt gaattcaaag
    72841 ttatgactcc tgagattggt gtaccatttg taactgaaca aactatggtt ttaagcacta
    72901 gtaaaaaaca agcgttagct aaagaattta ttgattggtt tggtcaatca gaaattcaag
    72961 tagaatatag taaaaaattt ggatctattc ctgcaaataa agatgcccta aaagagttac
    73021 ctgaagatac gaaaaaattt gttgatcaag tgaaaccaca aaatattgac tgggaagctg
    73081 ttggaaagca tttggatgaa tgggtagaaa aagctgaatt agaatacgta aaataagaaa
    73141 taagagttat tttttatgtc caagtctctc tattatttct aaatttaagg aagaaataaa
    73201 gagaggcttt tggtttagta atagagggag ttagtgagat gattaaattt gataatattc
    73261 aaattaaata tggtgatttt gttgcaattg ataatctgaa tttagatata catgaagggg
    73321 aattctttac atttcttggg ccttcaggat gtggtaaatc aactactttg agagcattgg
    73381 taggtttttt agatccatca tcaggaagta ttgaagttaa tggaacagat gtcactcatt
    73441 tggaacctga aaagcgtgga attggtattg tatttcaatc ttatgcgcta tttccaacta
    73501 tgactgtttt tgataatatt gcatttggtt taaaagttaa gaaggtagct ccagatgtta
    73561 ttaaagctaa agtatcagca gtggcagcaa aaattaagat ctctgatcaa cagttacagc
    73621 gtaatgtatc agaattatct gggggtcaac aacaaagggt agcattggct cgtgctctgg
    73681 ttcttgaacc taaaattctt tgtctagatg aaccattgtc aaaccttgac gcaaaattac
    73741 gtgtagattt gagaaaagag ttgaaaagac ttcaaaaaga gttaggtatt actactttat
    73801 atgttactca tgatcaagag gaagccttga ctttatctga tagaattgca gtctttaaca
    73861 atggatacat cgaacaggtc ggtacaccag tagagattta tcataattct caaactgaat
    73921 ttgtatgtga ttttattgga gatattaatg ttttgaccga tgaaacagtc cacgaagtat
    73981 tactgaaaaa tacaagcgtt ttcttagagg ataaaaaagg ttacattcga ttagagaaag
    74041 ttcgattcaa tcgtgaaact gaacaagatt ttattctaaa agggacaatt attgatgttg
    74101 agttttctgg agttacaatt cactatacaa taaaagtttc tgaaagtcag attcttaatg
    74161 taacaagtat tgatagtcag gctgctatta gatctgtcgg agaaagtgtg gaattattta
    74221 tcacaccatc agacgttctg caattttaag gaggtgcagt atgcgtcata aattaaattt
    74281 aaaagattgg cttattcgtt tagggttaat ctggttctta gtaacattta ttatttatcc
    74341 aaactttgat ctagtagtga atgtatttgt aaaaggagga gaattttccc ttgatgctgt
    74401 acatcgtgtt ctaaaatctc agagggcact tcagagtatt atgaacagtt ttaagttagc
    74461 attttcactc attattacag ttaatgtcgt aggtattctt tgtgttctat ttacagagta
    74521 ctttgatatt aaaggtgcta aaattttaaa attaggttat atgacctctt taatttatgg
    74581 aggagtggtt ttagcgactg gatataaatt tgtctatggt ccttatggat tgattacaaa
    74641 atttttacaa aatgttatcc cttctttaga ctctaactgg tttattgggt atggtgcagt
    74701 cttattcatt atgacatttt caggaactgc taatcataca ttgtttttaa caaatacaat
    74761 tcgaagcgtt gactatcaca ctattgaggc tgctcgaaat atgggagcaa aaccatttac
    74821 tgttttccga aaagtagtgt taccaacctt aattccaact ctatttgcac ttactattat
    74881 ggtttttctt agtggtttat ctgcagtagc agcacccatg attgttggtg gtaaagaatt
    74941 tcaaactata aatccaatga ttattacatt tgcagggatg gggaattctc gtgatttagc
    75001 tgccttactt gcaattattt taggtattgc aactacaatt ttgcttacta tcatgaataa
    75061 gatagaaaaa ggtggaaatt atatttctat ctctaagact aaagcgcctc ttaaaaaaca
    75121 aaaaattgcg tctaagcctt ggaatatcat tgctcacatt gtagcatatg gattgttcac
    75181 agttttcatg cttccactaa tttttatagt attatactca tttacagatc cagttgcaat
    75241 tcaaacaggt aacttaacat tatcaaactt tactttagaa aattatcgct tattctttag
    75301 taatagtgcg gcattctctc cattcttggt cagctttatt tattctatta ttgctgcgac
    75361 aacagcaaca attctcgcag ttgtatttgc tcgtgttgtc agaaaacata aatctcgttt
    75421 tgatttctta tttgaatatg gtgctctact tccttggtta ctaccaagta cacttttagc
    75481 agtaagttta ttatttactt ttaatcagcc acaatttctt gtcttgaatc agattttggt
    75541 aggtagtttg gtaattctac ttattgcata tatagttgta aaaatcccat tttcttatag
    75601 aatggtacgt gctattttat ttagtgttga tgatgagatg gaagatgcag caagaagtat
    75661 gggtgcttca cctttttata ctatgatgaa ggttatcatt ccatttattt taccggttgt
    75721 tctctctgtt attgctttaa actttaactc tttattaact gacttcgact tatctgtatt
    75781 cctttaccat cccctagctc aaccattagg tattacgatt cgatctgcag gtgatgaaac
    75841 agcaacatct aatgcacaag ctctggtatt tgtttataca attgttctga tgatcatttc
    75901 tggaacggta ttatacttca cacaaagacc ggggcgtaaa gtaaggaaat aatcatgaca
    75961 gccactagtc ttgggttatc aaatattgaa atagttgtca ggattgtttt atcagtagtc
    76021 attggtagta taattggttt agagagaggg agcaaatccc agcctgcagg catccgaact
    76081 tatagtattg tttgtctagc tgcatgtttg attatgatga cgaatgaata cgtatcttat
    76141 aaatttggga caggagatcc tacacgatta ggagctcaag ttatatcagg tgtgggtttt
    76201 ctaggcgctg gaacgattct tattacagat aaaaagaaaa ttacaggtct gacaactgca
    76261 gcaggcattt gggcttcggc aggaattgga ttagctattg gagtaggttt ttatgaggga
    76321 gctcttttag tagccatttc tgtttggggt gtgatatcca tgttccaacc actaaaaaaa
    76381 tatctgcaaa atcgttctaa aatgattgaa ttgtatatag tggttaaatc tacagaagcc
    76441 tataatcgtg tattggttta ttgtgcagaa aatggtatca gaatgaccga ttcaagaaca
    76501 gcgtttggag atgttaattc tgacagaatt gaatactttg atgttccgga caaaaaaata
    76561 gcgtcattta ttactctgga attatcaggt agatttgaac atcttcgact gatggaagaa
    76621 attgctaata ttgtaggtgt tatttatgtc gaagaaatta gctgaaattt agtaaacaaa
    76681 gggacagatg tttttgtcct tttgtttttt agatgtttta atcatctaat ttttgagtag
    76741 atttttgctc agaggttttt atgaaagatt ataaaatcaa ttttgattta ggtaaaatag
    76801 aatattttga taataattgt ttgatacaag tatacaaatt tatttctttt tatgatattt
    76861 gtgaaatggt gtttgccttt catttacctc ctgatgagtt gataacaaat gttatcttta
    76921 aagaaaaaat taactctatg ttaaaatgtt acattgacag gctattatat gtttttataa
    76981 atcctacaca ttttactgaa aaagttaatc tacaatttta tggtagtttt ttctcatatg
    77041 aatttatttg tcgtgaagtt ggaaacattc ttaaaaataa aggtgtgaaa tgcaatttaa
    77101 acttttttga aggggaagaa tatttgtaaa attaattttg tgaatttgtg gatcttaaat
    77161 aatttactaa attctcttgt taaaaaaaat taaatattgt atagtaatat tagaatgttc
    77221 gtaatggagg actgaaatga aaaatataaa tgggaaaaag gtaactattt atgatattgc
    77281 acgtttatca ggtttttctc caaaaacagt ttcacgagtt attaatggtg gagtaaatgt
    77341 taaagaagaa acttatcaag cgattcaaaa agttatagag gaattgtcgt atattccaaa
    77401 tgcgtatgca aaaaatttaa ctaaaaaaga agctataaat atattgattt ctgtaaaaaa
    77461 aatcgactct tttcctttaa tttggtttca tacgctgtta gataaagtgt tacggacgtg
    77521 taaagaattt ggtgttaatg ctatagttga gtactttgga gaggaggata caattagtaa
    77581 ttcaattata tcaagcacag gtagcctagt agatggtgtt attgtttttt atgaaagtgt
    77641 agatgatatc agaattcagt atttaaagaa gaaccatatg ccttttcttg ttttcggtga
    77701 atctcaaacg tctggagtag tctatgtatc taataataat tttcaagcta cttatgatat
    77761 gatgaaagct gtaactgaag aaaaatttaa aaatatgtgg ttgcttatgg gaggagaatc
    77821 ccatgttaat aaggatcgtg aaagaggtgt gcgttctttt ctgaatgata aaaattactt
    77881 tatggattta aaagtcattt atggcttatc tacaattgat tcagtttatt cttatgcaat
    77941 gcagcacttg actacccaaa attatccgga cattattttt gtttcaggag atgaaaaggt
    78001 tcagggcttg attcgtgcgt gctatgagaa aggaattctt attccagatg atatttctat
    78061 cattggattt gataatattc ctatttctca gtattatact ccagctttgt ctacaattgc
    78121 tcccaattat gttaaattgg ctaaagaaat gatagaaggt gttttagcaa ttattaaagg
    78181 ggaaagtgtc acatctgttg aagtttctcc taaatttgtt aggagacaga gtttctagta
    78241 ttgtttaatt cttgaaaatc ctagtggaaa agatggagtg ttctaaaata agttctgttt
    78301 agcctccatt cagtttctat tgagttggat ccaatttcta acaagtggga catgttcatg
    78361 ttcgatctaa ggaagacatg gtcacattcg aatgatattt tcaaaaaaat cgtaaaaaag
    78421 tcttgacaaa gaaaaaacaa agtattaaaa taagttcaac aaatcagaaa agtaactatt
    78481 tttgatcttc agggagcctg tggtggttgt gaataggtgg ttggaagtag tgaaagtggg
    78541 ctgattttga aaatgaattt gaaacaatga aaattcggtg cgcacacctt acagtgcagc
    78601 ttgttgttaa acaaggcaga gatgtaaagg gatagtccct ttataattga ggtggcaccg
    78661 cgttaccaac gccctcacac ggaagtatat tttgtgtgtg ggcttttttc tatccgtcgt
    78721 ttggtttatc ttttattagg gccttaagtc gctttgatga acttgagttc tatctacagc
    78781 tccttgccta ctactaaaag caaacaaaaa gctggactaa tacgaaaaaa gctagtaata
    78841 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggttgctcaa aacactgttt
    78901 tgaggttgtg gatagaactg acgaagtcag ctcaaaatac tgttttgagg ttgtggatag
    78961 aactgacgaa gtcagctcaa aacactgttt tgaggttgca gatagaactg acgaagtcag
    79021 taaccatacc tacggcaagg cgacgttgac gcggtttgaa gagattttcg aagagtataa
    79081 aggtgtatcg aaataaaaat ctcctcatca atatctctgg tcgtggaggc aaggacctag
    79141 ctgcgattgc agattaccta gaagctaaaa aataatagat ggaaaaatta cagtcttttc
    79201 tctcacagag agcttgtggt tgctgaaaac aagcagagaa agctgtaaag ttgggttcat
    79261 ctgaaacgag agaagaaaac atcattctca agggagtgcc ctttatcgca cagcctgtta
    79321 caggaggtat ctgagacagg aatgagagat aggagaaatc ctataattga ggtggcaccg
    79381 cgaatttcgt cctcacgcaa gttattttgc gtggggattt ttcatacagt caccacggac
    79441 tagaagtaga actgaaaggg aaattacaat ggaacgaatc attcatggag atgtcttatc
    79501 accaatcttg gcttatatgc gcttaaaggg gcaacacaag gttatcttag agagtattcc
    79561 gagagacaag gaaacagctc gtttttctat cttagcctat aatcctgttt ttgagattaa
    79621 gtttgaaaat ggagttcttt atcaaaatgg tcaagtgatt gatcgagatc ccttggattt
    79681 cctttatgaa gtgattcata agagtcagca ccactcagag ctaccttttg gtggtggagc
    79741 cattggtttt gtgggttacg atatgatttc gctttatgaa gaaattggtc aaatccctga
    79801 ggatacaatt gggacgccag acatgcattt ctttgtctat gagagctata tggtctttga
    79861 ccacaagaag gagaagatac atgtcataga ggatgctctc tatagtgagc gcagtcaaga
    79921 ggccttggaa aaatccttga accaagtgct tgaggaatta cgcattcctg ctccaaatga
    79981 atttgaagac ttggatttat caccacttga cttcaaaccg catatcgctc cacataagtt
    80041 tgaggtaatg gtagaaacag ctcgtgactt gattcgtaat ggtgatatgt tccaatgtgt
    80101 actcagccag cgtttctcag cagaagttac tggaaattca tttgacttct acagaaatct
    80161 ccgcgtgacc aatccatcca attacctcta tttctatgat tttggggatt atcaaatcat
    80221 cggagctagt ccagaaagtt tagtttctgt caaaaatggc atcgtgacaa ccaatccgat
    80281 tgcagggacg cgaccaagag gggttacgga tgaagaagac aagaccttgg cgactgacct
    80341 cctctctgat gagaaggaaa cagcagaaca tcgaatgttg gtagacttgg ggcgtaacga
    80401 tattggccgc atctctgaaa cggccagtgt ccaagttact aagtatatga aggtggagct
    80461 cttccgctac gtcatgcatt tgaccagcgt ggtcaagggg cgtttgcttg cagaactcac
    80521 tgccatggat gccttgaaag caacgcttcc tgctggaacc gtttctggag caccaaagat
    80581 tcgggcgatg agacgcatct atgaactgga aacggaaaaa cggggcgtat atgcaggagc
    80641 aatcggctac ttgtctgcga cgggtgatat ggatttggcc attgccatcc gaaccatgat
    80701 tctcaaaaat caaagagcct atgtgcaggc tggggcaggg attgtctacg actctatcgc
    80761 ccaaaacgaa taccaagaaa ccattaacaa agcaaaatct atgactagaa ttggagaact
    80821 aagaccatga ttttattgat tgacaactat gattctttta cctataactt ggcccaatac
    80881 attgggaatt ttgcagaagt tcaggttctg agaaatgatg attccaagct gtatgaagaa
    80941 gctgaaaaag cagatggtct ggtcttttct cctggtcctg gttggccagt tgatgctgga
    81001 aagatggaag acatgattcg tgattttgca ggcaagaagc cgattctagg gatttgtttg
    81061 ggccaccaag ccattgcaga agtctttggt ggtaagctag gtttggctcc aaaagtcatg
    81121 catgggaaac agagcaatat caactttgaa gcgccatctg ttttgtatca aggtattgag
    81181 gatggacgtg cggtcatgcg ttatcacagt attttgattg aggaaatgcc agaagacttt
    81241 gaagtgacag ctcgttcgac tgatgaccaa gccatcatgg ggattcaaca taaaaaccta
    81301 ccgatttatg gcttccagta ccatccagag agcattggaa cgccagacgg cttgtcttct
    81361 attcggaatt ttatcgagaa ggttgtaaag tgaggaaact aggatgaaag agattattga
    81421 aaaactagca aaatttgaaa atttatcagg tgtggaaatg acggatgtca ttgagcgtat
    81481 cgtaactggg cgtgtaactg aagcgcagat tgcttctctc ctcttagctc ttaagatgaa
    81541 gggggaaaca cctgaagaac gcacagccat tgcccaagtc atgagaggac atgcccagca
    81601 tattccaact gagattcatg atgccatgga caactgtggt acaggtgggg acaagtcttt
    81661 cagttttaat atttccacaa ctgcagcctt tgtcttggct ggtggcggta ttcacatggc
    81721 caagcatggt aaccgctcga tttcttctaa atctggttcc gcagatgtcc tcgaagcctt
    81781 gggaatcaat cttgacctca aaccagctga actaggtaag gtctttgata aaactggaat
    81841 cgtctttctc ttcgctaaaa atatgcaccc agctatgaaa tacatcatgc cagctcgttt
    81901 ggaattggga attccaacga ttatgaactt gactggtcca ctgattcatc caatggcttt
    81961 agaaacacag cttcttggaa ttagtcgtcc agaactccta gaaagtacag ctcaggtttt
    82021 gaaaaatatg ggtcgcaaac gtgccatcgt ggttgctgga ccagaagggt tggatgaagc
    82081 tggcttgaac ggaacaacca agattgcact tcttgaaaat ggcgaaatca gcttgtcaag
    82141 ctttactcca gaggatttgg gaatggaagg ctatgctatg gaagatgttc gtggtgggaa
    82201 tgctcaggaa aatgcagaaa ttttgcttag cgttctgaaa aacgaagcaa gtccattctt
    82261 ggaaacgaca gtcttgaatg ctggtcttgg tttctatgct aatggtaaga ttgatagcat
    82321 caaggaagga gttgccttgg cccgtcaagt gattgctaga ggcaaggccc ttgaaaaact
    82381 cagactgtta caggagtatc aaaaatgagt caggaatttt tagcacgaat cttagagcag
    82441 aaggcgcgtg aggtggagca aatgaagctg gagcaaatcc agcctctgcg ccagacctat
    82501 cgcttggcag aatttttgaa gaatcatcag gaccgcttgc aggtaatcgc tgaggtcaag
    82561 aaagctagcc ctagtttggg agatatcaat ctcgatgtgg atattgtgca acaggcccag
    82621 acttatgaag aaaacggagc agtgatgatt tcggtgttga cagatgaggt tttctttaaa
    82681 gggcatttga attatctacg ggaaatttcc agtcaggtag agattccgac gctcaacaaa
    82741 gactttatca tagatgaaaa gcaaatcatc cgcgctcgca atgcaggtgc gacagttatc
    82801 ttgcttattg tggcagcctt gtccgaagaa cgcctcaagg aactgtatga ctacgcgaca
    82861 gagcttggtc tggaagtctt agtggagact cacaatctag ctgaactaga ggtagcccac
    82921 agacttggtg ctgagattat cggggtcaac aaccgcaact tgactacctt tgaggtcgac
    82981 ttgcagacca gtgtagattt agccccttac tttgaggaag gtcgctatta catttctgaa
    83041 tctgccattt tcacagggca ggatgcggaa cgactagccc catactttaa cggaattttg
    83101 gtagggacag ctcttatgca ggcagaaaat gtggcccaga gaatcaagga gttgcagatt
    83161 gacaaaggtt aaaatttgtg gactatcgac caaagaagcg gtggaaacag ccgtttcagc
    83221 aggagccgac tatatcggtt ttgtctttgc acctagtaaa agacaggtga ctttagaaga
    83281 ggcagctgag ttggcaaagc ttattcctgc agatgtgaaa aaggttggag tatttgtttc
    83341 accaagtcgg gtagaactgc tggaagcgat tgacaaagtt ggcttggact tggttcaagt
    83401 tcacggtcag gtggcagctg atttatttga gaatttgcct tgtgccagta ttcaggctgt
    83461 gcaggtagat ggaaatgggc atgtccccaa ttctcaggca gattatctac tctttgatgc
    83521 ccctgtggca ggaagtggtc agtcctttga ttggggtcaa ctggatacga ctggactagc
    83581 acagcccttc tttatcgcag gtggccttaa tgaagataat gtagtaaaag caattcaaca
    83641 ttttactccc tatgcagtag atgtatcgag cggagtggag acagatggac aaaaagatca
    83701 tgaaaagatt agaagattta tagagagggt aaagcatggc atatcaggaa ccaaataaag
    83761 atggatttta cggaaaattc ggcggacgtt ttgtcccaga aacattgatg acagcagttt
    83821 tggagttgga gaaggcctac cgtgaaagtc aggcagaccc aagtttccaa gaggaattaa
    83881 accagctttt gcgccagtac gtaggacgtg aaactcctct ttattacgca aaaaacttga
    83941 cccagcatat cggcggagcc aagatttatc tcaaacggga agaccttaac catacaggag
    84001 cccacaagat taacaatgcc ttgggacaag tttggcttgc caaacgcatg ggtaaaaaga
    84061 aaattatcgc agaaactggt gctggtcagc acggtgtggc aactgcaact gctgcggccc
    84121 tctttaacat ggaatgtacc atctacatgg gtgaggaaga tgtcaaacgc caagccctca
    84181 atgtcttccg tatggagctt ttgggagcta aggtcgaggc cgtgacagat ggttcgcgcg
    84241 tgctcaagga tgcggtcaat gcagcccttc gttcatgggt ggctaatata gatgataccc
    84301 actatatcct tggttctgcc ttggggcctc atccatttcc agaaattgtt cgtgacttcc
    84361 aaagtgtcat tggtcgagag gctaaacaac agtaccgtga cttgacagga caaaatctgc
    84421 cagatgccct agtagcctgt gttggtggtg ggtcgaatgc catcggtctc ttccatccct
    84481 ttgtagaaga tgagtcagta gccatgtatg gagctgaagc ggctggattt ggtgtggata
    84541 cggagcacca cgcagctacc ttgaccaagg gtcgtccagg tgtccttcac ggttccctca
    84601 tggatgtgct ccaagatgcc catggtcaaa ttcttgaagc cttctctatc tcagcaggtt
    84661 tggactatcc tggtatcggt ccagagcatt ctcactacca cgatattaaa cgtgccagct
    84721 atgtccctgt gacagacgaa gaagccttgg aaggattcca actcttgtct cgtgtggaag
    84781 ggattatccc agctttggaa tctagccatg ctatcgcctt tgcggtgaaa ttggccaaag
    84841 aacttggacc agaaaagtct atgattgtat gcctatcagg tcgtggggac aaggatgtgg
    84901 ttcaagtaaa agaccgcttg gaagcagatg cagcaaagaa gggagaagct catgcctaag
    84961 acactaacaa aaaaattaaa tgctattaaa gcagctggaa aaggaatttt tgttccctat
    85021 atcatggctg gtgaccacga aaaaggtttg gatggtcttg ctgaaacaat tcacttttta
    85081 gaagatttgg gtgtctctgc aattgaagtg ggtattccct tttcagaccc tgttgcagat
    85141 ggacctgtta tcgaagaagc tggcttgcgc agtttagccc acgggacctc tacccaggct
    85201 ttagttgaaa ccttgaaaac cattgaaaca gagattccac tggtcatcat gacctacttc
    85261 aaccccctct ttcagtacgg tgtggagaac tttgtcaaag atctggctga tacagctgtg
    85321 aagggcttga ttatcccaga cctgcctcat gaacatgcca actttgtaga accatttttg
    85381 gcagatacag atatcgcctt gattccttta gtaagcttga ccacaggaat tgagcgccag
    85441 aaagagttga ttgaaggggc ggagggattc gtctatgccg ttgccatcaa tggggtaaca
    85501 gggaaatcag gcaattaccg tgcagatttg gacaagcact tggcgcaact tcatcaagtg
    85561 gccgacatcc cagtcttgac aggttttggt gtatctagtc aagccgatct ggaacgcttc
    85621 aatgcggtgt cagatggtgt tatcgtcggt tcgaaaatag taaaagctct ccaccaagga
    85681 gagccgattc aggactttat caaacaagca gtagcttacc aaaaataatt aaacaagtag
    85741 caagtaagag gaaaggcacg aaaggaagtc tttccttttt cttttgcagg agaaaggcta
    85801 gttttatagt gaattgaatc tggaatatta cactacggtt cctaaaatat tttaagaaag
    85861 tgatttgaat ttcccaataa atttgttcag tttttaattg attttactat agaagatata
    85921 attttctaaa ttactctgac acagaacttt aagaaaaagc taattattgt agtaatttct
    85981 ttaagaaaat gatataattc attaaaaagt atttggagga ggaagaatta tgttgaatca
    86041 ggatctcttt gattcgcttg aggcacaaaa aattgtagat actttgatga aagggcaaaa
    86101 agattatgta gatgaacgtc tagaaaaaag agagacaatg atagtgtcga atggttatgc
    86161 atggacgcga cctaatcata ttgatactgc atttgcatca gcagatttgt ttgagtataa
    86221 attacaatta gcaggacaga cttggggata tttagaattt gaaacaaata cagaaaaata
    86281 tgggaaagta ttgttaatta taaagggtaa gaagcgactt acgaaccaat ttcctttggt
    86341 acaaaaaaat aagagtggct acttatttga atatgctcaa atgaatacac tttatcttaa
    86401 tcaacattct tcctacaaaa atgatgaaga tagtcattcc tttccaattc agatggagtt
    86461 agtttctgat gaaatgattc aagaaattga acaagctacc aaaaattcga atatcgaaaa
    86521 atttatgatt ttaacttatg aggcggactc agaaaacaat attatatctg tagatgttgt
    86581 tatgcctgat gcacgaactg gtcagttaca cttgattcaa gatttgtctg agtatattca
    86641 atcaagttcg taccatttcg aagaagctaa ataccaagat attcctaatt tttcagaatt
    86701 atcggaaaca gaagattttg aaattattcc aagaatagaa aaacaagaag gtcaaaagta
    86761 gtaaggagta tgtaaatgtt taatggtcgg gtattgaaag aattacggct gttaaatggt
    86821 ttaagtagag cagaattagc tcagagaatt aatttaacgg aacaagccat ttggcagttt
    86881 gagtccaacg aaacgaaacc taaattatca accaaaatgc atttggccaa ccaatttcat
    86941 gttgatttaa cttattttga acaggaagaa gagagcattc gatttgattc ttctgtaatt
    87001 gcctttagaa atgcagacct agcaacacgg aaaacaatag atattcaaac tatgtattta
    87061 cataaggtag atagtttgat tgattatttt gaaagttttg taattatacc taatattaca
    87121 attcatgacc taagtaatgt agtgagtgaa tcttatcata agggagaatc cattgaggaa
    87181 ttggctcttt atgccaggga aaaattaggt atttcaaaag ataatcatga tttgctttat
    87241 aaattagaac gttcaggcat ctatatcgtg gaacgattaa ttaatggcca agctgatgct
    87301 tatagcgcat ggtcaaaatt gggaagacct tatattgtgt tgggaacgaa taaatcatct
    87361 gtacgtcgaa attttgactt agctcatgag ctaggacata ttcttttaca taaatataaa
    87421 gatatgaatg aagatggcga tcgtttggag caagaagcaa attattttgc atcatgtttt
    87481 ttattgccaa aagaagagtt tttagtcaaa tttgaagaga gggttggcaa gcgtgtcagc
    87541 aatcctgata gttatatttt attgaagtcg gatttgaatg tttcgataca ggctttagag
    87601 tatcgagctt ttaagttagg attattgact ccaaagcaac attcttactt ttatcgtcaa
    87661 attgcgcaaa aaggttacaa aatgattgaa cctttggatg atcaaatttt tgttaaaaaa
    87721 ccaagcaaag taaagagtat tctggacgtc gttttgagta atcatctagt cagtctagcg
    87781 actataatgt ctaaacaaag tattcgttta cagtttataa gcgaaatatt ttcagtcgaa
    87841 atgaaatttt ttgatcagta tcaagaagat agaagaacag atcgatttga taacatcatc
    87901 cctttgtaca aaagaaataa tttataattt aactgtgaaa taatttcatg aaggacatat
    87961 ggcagaaatt ggattttatt agacaagcag tagcttacca aaaataatca aacaagtagc
    88021 aagtaagagg aaaggcacga aaggaagtct ttcctttttc ttttgcagga gaaaggccag
    88081 gatacccgtc gcagaagcga actgaatcaa gatcagtaac tccgttacgc taaagacgag
    88141 agcacaagaa gctaaaaaaa ggaaatcccc tgcacccatg cggatatcga taaaatgagc
    88201 caaaattcca agtatgagga aggagaccat gaccagattc cagccagagg aagctattag
    88261 gattaggtgg caagtcatcc agaccagtaa gggatattcc tgatggtgaa agtcgtagat
    88321 acccaaggtc aaaccagcgg tgattaggac gacttgcccc aaggaaagca atttccaaga
    88381 gtaaagcaga aagaggagtc ctaagactaa ttcaaagagg gcataccaga caggatagcg
    88441 aactttgcag tagcgacagc gaaagcgatt gaagacctgt gagagaatcg gaatcaaatc
    88501 taagggacgc aagcgagtct gacaggaatc gcagtgactg gctgaactga taatggattg
    88561 ctctggaaaa cggtcaatga ccaaaccaag aaaggaagcg agaatgctcc cgacgagaaa
    88621 aaaataaaaa tcaatcatac ttatctattc gtaaaaaatg ggagaaatag tataatggag
    88681 aaacatagat aagatggtga ggaaaagatg acaattcgtt ttgaagaaaa ggtgagtata
    88741 gaaaacgctc aatttgtatg ccagtggtcc aactccctag gcaaatcctt tcaagaacaa
    88801 tggatgggac caaggattcc ttttctactg acccttcaag ccttggaagg agtcttttca
    88861 atctttgatg aacaagagtt tgtgggattt atccagaaaa tcaggctaga agacagcaat
    88921 cttcatatcg ggagattttt tatcaacccc cagaaacagg agcaaggctt aggtagccag
    88981 gctttaagga aatttgttag tttggccttt gaaaatgaag atatagatag tatttctcta
    89041 aatgtcttcg aggcaaatca aagagctcag aatctttacc aaaaagaagg atttgaaatc
    89101 gttcaaatgg ttgaagcacc tgtacgaaaa tatagtatat tgaaactaga atagtacacc
    89161 tctacttcta aaacattgtt agaaatcgat ttgactgtc
//
LOCUS       DBEJJV010000003        83569 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.003, whole genome shotgun sequence.
ACCESSION   DBEJJV010000003 DBEJJV010000000
VERSION     DBEJJV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 83569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.003"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..516)
                     /locus_tag="ACL3GT_000205"
                     /pseudo
     CDS             complement(1..516)
                     /locus_tag="ACL3GT_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            complement(890..1039)
                     /locus_tag="ACL3GT_000206"
     CDS             complement(890..1039)
                     /locus_tag="ACL3GT_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
                     /protein_id="HGR0515939.1"
                     /translation="MEKFNFKNNIGQENKLLQIEIYKFTNFCKLQNYTSVNIFSKDIF
                     EAIVN"
     gene            1004..1123
                     /locus_tag="ACL3GT_000207"
     CDS             1004..1123
                     /locus_tag="ACL3GT_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HGR0515940.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(1219..2565)
                     /gene="glnA"
                     /locus_tag="ACL3GT_000208"
     CDS             complement(1219..2565)
                     /gene="glnA"
                     /locus_tag="ACL3GT_000208"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HGR0515941.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(2602..2958)
                     /gene="glnR"
                     /locus_tag="ACL3GT_000209"
     CDS             complement(2602..2958)
                     /gene="glnR"
                     /locus_tag="ACL3GT_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HGR0515942.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYENQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(3035..3562)
                     /locus_tag="ACL3GT_000210"
     CDS             complement(3035..3562)
                     /locus_tag="ACL3GT_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0515943.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(3698..4894)
                     /gene="pgk"
                     /locus_tag="ACL3GT_000211"
     CDS             complement(3698..4894)
                     /gene="pgk"
                     /locus_tag="ACL3GT_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HGR0515944.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     VALTEK"
     gene            complement(4984..9894)
                     /locus_tag="ACL3GT_000212"
     CDS             complement(4984..9894)
                     /locus_tag="ACL3GT_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HGR0515945.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYRFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFEWGMTVQDTSLPRPLAENIVPG
                     ATVIGSTFPDTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGHEVNFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            10187..11817
                     /locus_tag="ACL3GT_000213"
                     /pseudo
     CDS             10187..11817
                     /locus_tag="ACL3GT_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0005436 - sodium:phosphate symporter
                     activity [Evidence IEA];
                     GO_process: GO:0044341 - sodium-dependent phosphate
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            complement(12376..13983)
                     /locus_tag="ACL3GT_000214"
     CDS             complement(12376..13983)
                     /locus_tag="ACL3GT_000214"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HGR0515946.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAAAMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDTEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(14373..14960)
                     /gene="rpoE"
                     /locus_tag="ACL3GT_000215"
     CDS             complement(14373..14960)
                     /gene="rpoE"
                     /locus_tag="ACL3GT_000215"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HGR0515947.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(15088..15537)
                     /locus_tag="ACL3GT_000216"
     CDS             complement(15088..15537)
                     /locus_tag="ACL3GT_000216"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0515948.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(15542..15931)
                     /locus_tag="ACL3GT_000217"
     CDS             complement(15542..15931)
                     /locus_tag="ACL3GT_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HGR0515949.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(15959..16609)
                     /locus_tag="ACL3GT_000218"
     CDS             complement(15959..16609)
                     /locus_tag="ACL3GT_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0515950.1"
                     /translation="MRDKQTFLMKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIR
                     GDLPDYLTILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIV
                     TFKNIYQRPRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQI
                     VLGLYLVSVLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(16599..17162)
                     /locus_tag="ACL3GT_000219"
     CDS             complement(16599..17162)
                     /locus_tag="ACL3GT_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0515951.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(17327..17561)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(17615..18118)
                     /locus_tag="ACL3GT_000220"
     CDS             complement(17615..18118)
                     /locus_tag="ACL3GT_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HGR0515952.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(18311..19141)
                     /locus_tag="ACL3GT_000221"
     CDS             complement(18311..19141)
                     /locus_tag="ACL3GT_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0515953.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(19126..20808)
                     /locus_tag="ACL3GT_000222"
     CDS             complement(19126..20808)
                     /locus_tag="ACL3GT_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0515954.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LISDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(20910..21167)
                     /locus_tag="ACL3GT_000223"
     CDS             complement(20910..21167)
                     /locus_tag="ACL3GT_000223"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515955.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(21174..21722)
                     /locus_tag="ACL3GT_000224"
     CDS             complement(21174..21722)
                     /locus_tag="ACL3GT_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HGR0515956.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(21737..22585)
                     /locus_tag="ACL3GT_000225"
     CDS             complement(21737..22585)
                     /locus_tag="ACL3GT_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HGR0515957.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            22773..24122
                     /gene="trkA"
                     /locus_tag="ACL3GT_000226"
     CDS             22773..24122
                     /gene="trkA"
                     /locus_tag="ACL3GT_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HGR0515958.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            24126..25565
                     /locus_tag="ACL3GT_000227"
     CDS             24126..25565
                     /locus_tag="ACL3GT_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0515959.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKMVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(25690..26091)
                     /locus_tag="ACL3GT_000228"
                     /pseudo
     CDS             complement(25690..26091)
                     /locus_tag="ACL3GT_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
     gene            27489..27773
                     /locus_tag="ACL3GT_000229"
     CDS             27489..27773
                     /locus_tag="ACL3GT_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515960.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            28100..28318
                     /locus_tag="ACL3GT_000230"
     CDS             28100..28318
                     /locus_tag="ACL3GT_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515961.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(28685..31009)
                     /gene="pflB"
                     /locus_tag="ACL3GT_000231"
     CDS             complement(28685..31009)
                     /gene="pflB"
                     /locus_tag="ACL3GT_000231"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HGR0515962.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            31403..32464
                     /gene="dinB"
                     /locus_tag="ACL3GT_000232"
     CDS             31403..32464
                     /gene="dinB"
                     /locus_tag="ACL3GT_000232"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HGR0515963.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            complement(32611..33456)
                     /locus_tag="ACL3GT_000233"
     CDS             complement(32611..33456)
                     /locus_tag="ACL3GT_000233"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HGR0515964.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(33487..33624)
                     /locus_tag="ACL3GT_000234"
     CDS             complement(33487..33624)
                     /locus_tag="ACL3GT_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515965.1"
                     /translation="MRYQTHYQLKQKLWLDPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            33711..34682
                     /locus_tag="ACL3GT_000235"
     CDS             33711..34682
                     /locus_tag="ACL3GT_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HGR0515966.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALKLLSDPNREQFQHDNRQVDLKILARHIHRLKKKQSDWKVQYTRCLD
                     IIFPELDKIVGKHSEYTYQLLTRYPNPQKRIEAGFDKLIEIKRLTASKIQDILSVAPR
                     SIETTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILA
                     EIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKVCARF
                     SPAFKAYLKTKLEQGKHYNVAIIHLAKKLIRTLFYILKKSCHLTNKK"
     gene            complement(34881..36770)
                     /locus_tag="ACL3GT_000236"
     CDS             complement(34881..36770)
                     /locus_tag="ACL3GT_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HGR0515967.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWSRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNFFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKTLQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            36908..38473
                     /locus_tag="ACL3GT_000237"
     CDS             36908..38473
                     /locus_tag="ACL3GT_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0515968.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            38473..39213
                     /locus_tag="ACL3GT_000238"
     CDS             38473..39213
                     /locus_tag="ACL3GT_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0515969.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(39322..39537)
                     /locus_tag="ACL3GT_000239"
     CDS             complement(39322..39537)
                     /locus_tag="ACL3GT_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515970.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(40408..41658)
                     /gene="ilvA"
                     /locus_tag="ACL3GT_000240"
     CDS             complement(40408..41658)
                     /gene="ilvA"
                     /locus_tag="ACL3GT_000240"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004794 - threonine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HGR0515971.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(41708..42064)
                     /locus_tag="ACL3GT_000241"
     CDS             complement(41708..42064)
                     /locus_tag="ACL3GT_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0515972.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEIFGDE"
     gene            complement(42302..42538)
                     /locus_tag="ACL3GT_000242"
     CDS             complement(42302..42538)
                     /locus_tag="ACL3GT_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0515973.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKY"
     gene            complement(42645..43667)
                     /gene="ilvC"
                     /locus_tag="ACL3GT_000243"
     CDS             complement(42645..43667)
                     /gene="ilvC"
                     /locus_tag="ACL3GT_000243"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HGR0515974.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(43733..44209)
                     /gene="ilvN"
                     /locus_tag="ACL3GT_000244"
     CDS             complement(43733..44209)
                     /gene="ilvN"
                     /locus_tag="ACL3GT_000244"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HGR0515975.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(44202..45902)
                     /locus_tag="ACL3GT_000245"
     CDS             complement(44202..45902)
                     /locus_tag="ACL3GT_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HGR0515976.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(46102..47769)
                     /locus_tag="ACL3GT_000246"
     CDS             complement(46102..47769)
                     /locus_tag="ACL3GT_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HGR0515977.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(47772..48137)
                     /locus_tag="ACL3GT_000247"
     CDS             complement(47772..48137)
                     /locus_tag="ACL3GT_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0515978.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(48294..48482)
                     /gene="rpmB"
                     /locus_tag="ACL3GT_000248"
     CDS             complement(48294..48482)
                     /gene="rpmB"
                     /locus_tag="ACL3GT_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HGR0515979.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(48601..49083)
                     /locus_tag="ACL3GT_000249"
                     /pseudo
     CDS             complement(48601..49083)
                     /locus_tag="ACL3GT_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
     gene            complement(49352..50896)
                     /locus_tag="ACL3GT_000250"
     CDS             complement(49352..50896)
                     /locus_tag="ACL3GT_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HGR0515980.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            51109..51411
                     /gene="gatC"
                     /locus_tag="ACL3GT_000251"
     CDS             51109..51411
                     /gene="gatC"
                     /locus_tag="ACL3GT_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HGR0515981.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            51411..52877
                     /gene="gatA"
                     /locus_tag="ACL3GT_000252"
     CDS             51411..52877
                     /gene="gatA"
                     /locus_tag="ACL3GT_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HGR0515982.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWNHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            52877..54319
                     /gene="gatB"
                     /locus_tag="ACL3GT_000253"
     CDS             52877..54319
                     /gene="gatB"
                     /locus_tag="ACL3GT_000253"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HGR0515983.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            54448..55008
                     /gene="efp"
                     /locus_tag="ACL3GT_000254"
     CDS             54448..55008
                     /gene="efp"
                     /locus_tag="ACL3GT_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HGR0515984.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            55030..55419
                     /locus_tag="ACL3GT_000255"
     CDS             55030..55419
                     /locus_tag="ACL3GT_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0515985.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            55412..55834
                     /gene="nusB"
                     /locus_tag="ACL3GT_000256"
     CDS             55412..55834
                     /gene="nusB"
                     /locus_tag="ACL3GT_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HGR0515986.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     AVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(55883..56077)
                     /locus_tag="ACL3GT_000257"
     CDS             complement(55883..56077)
                     /locus_tag="ACL3GT_000257"
                     /EC_number="3.4.26.-"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR0515987.1"
                     /translation="MILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFFNFL
                     NHAKPIWIFVYNYIYYHFFR"
     gene            complement(56132..56583)
                     /locus_tag="ACL3GT_000258"
                     /pseudo
     CDS             complement(56132..56583)
                     /locus_tag="ACL3GT_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(56601..56786)
                     /gene="briC"
                     /locus_tag="ACL3GT_000259"
     CDS             complement(56601..56786)
                     /gene="briC"
                     /locus_tag="ACL3GT_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HGR0515988.1"
                     /translation="MTGTETFTVISTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(56945..57712)
                     /locus_tag="ACL3GT_000260"
     CDS             complement(56945..57712)
                     /locus_tag="ACL3GT_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HGR0515989.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(57709..58575)
                     /gene="accD"
                     /locus_tag="ACL3GT_000261"
     CDS             complement(57709..58575)
                     /gene="accD"
                     /locus_tag="ACL3GT_000261"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HGR0515990.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(58612..59979)
                     /gene="accC"
                     /locus_tag="ACL3GT_000262"
     CDS             complement(58612..59979)
                     /gene="accC"
                     /locus_tag="ACL3GT_000262"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0004075 - biotin carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HGR0515991.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASRNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(59991..60413)
                     /gene="fabZ"
                     /locus_tag="ACL3GT_000263"
     CDS             complement(59991..60413)
                     /gene="fabZ"
                     /locus_tag="ACL3GT_000263"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0019171 -
                     (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HGR0515992.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(60410..60895)
                     /gene="accB"
                     /locus_tag="ACL3GT_000264"
     CDS             complement(60410..60895)
                     /gene="accB"
                     /locus_tag="ACL3GT_000264"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HGR0515993.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(60898..62133)
                     /gene="fabF"
                     /locus_tag="ACL3GT_000265"
     CDS             complement(60898..62133)
                     /gene="fabF"
                     /locus_tag="ACL3GT_000265"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HGR0515994.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(62155..62886)
                     /gene="fabG"
                     /locus_tag="ACL3GT_000266"
     CDS             complement(62155..62886)
                     /gene="fabG"
                     /locus_tag="ACL3GT_000266"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HGR0515995.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(62920..63840)
                     /gene="fabD"
                     /locus_tag="ACL3GT_000267"
     CDS             complement(62920..63840)
                     /gene="fabD"
                     /locus_tag="ACL3GT_000267"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HGR0515996.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTSLLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTTHLAHVEDQASLVALLKK"
     gene            complement(63833..64807)
                     /gene="fabK"
                     /locus_tag="ACL3GT_000268"
     CDS             complement(63833..64807)
                     /gene="fabK"
                     /locus_tag="ACL3GT_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018580 - nitronate monooxygenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HGR0515997.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(64926..65150)
                     /locus_tag="ACL3GT_000269"
     CDS             complement(64926..65150)
                     /locus_tag="ACL3GT_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0515998.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(65210..66184)
                     /locus_tag="ACL3GT_000270"
     CDS             complement(65210..66184)
                     /locus_tag="ACL3GT_000270"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HGR0515999.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(66184..66618)
                     /locus_tag="ACL3GT_000271"
     CDS             complement(66184..66618)
                     /locus_tag="ACL3GT_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR0516000.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(66712..67497)
                     /locus_tag="ACL3GT_000272"
     CDS             complement(66712..67497)
                     /locus_tag="ACL3GT_000272"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HGR0516001.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            67866..69230
                     /locus_tag="ACL3GT_000273"
     CDS             67866..69230
                     /locus_tag="ACL3GT_000273"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HGR0516002.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            69233..69604
                     /locus_tag="ACL3GT_000274"
     CDS             69233..69604
                     /locus_tag="ACL3GT_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HGR0516003.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            69818..71092
                     /gene="serS"
                     /locus_tag="ACL3GT_000275"
     CDS             69818..71092
                     /gene="serS"
                     /locus_tag="ACL3GT_000275"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HGR0516004.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVEAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(71117..72016)
                     /locus_tag="ACL3GT_000276"
     CDS             complement(71117..72016)
                     /locus_tag="ACL3GT_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HGR0516005.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(72126..72674)
                     /locus_tag="ACL3GT_000277"
     CDS             complement(72126..72674)
                     /locus_tag="ACL3GT_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HGR0516006.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(72892..74214)
                     /locus_tag="ACL3GT_000278"
     CDS             complement(72892..74214)
                     /locus_tag="ACL3GT_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005283 - amino acid:sodium symporter
                     activity [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/glycine:cation symporter family protein"
                     /protein_id="HGR0516007.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFTFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(74305..74393)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(74557..76893)
                     /locus_tag="ACL3GT_000279"
     CDS             complement(74557..76893)
                     /locus_tag="ACL3GT_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HGR0516008.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKGQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQIGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(76997..77545)
                     /locus_tag="ACL3GT_000280"
     CDS             complement(76997..77545)
                     /locus_tag="ACL3GT_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HGR0516009.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(77542..77844)
                     /gene="zapA"
                     /locus_tag="ACL3GT_000281"
     CDS             complement(77542..77844)
                     /gene="zapA"
                     /locus_tag="ACL3GT_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HGR0516010.1"
                     /translation="MANLNRFKFTFGKKTLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            77931..78812
                     /gene="rnhC"
                     /locus_tag="ACL3GT_000282"
     CDS             77931..78812
                     /gene="rnhC"
                     /locus_tag="ACL3GT_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HGR0516011.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            78816..79430
                     /gene="lepB"
                     /locus_tag="ACL3GT_000283"
     CDS             78816..79430
                     /gene="lepB"
                     /locus_tag="ACL3GT_000283"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HGR0516012.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            79664..82030
                     /locus_tag="ACL3GT_000284"
     CDS             79664..82030
                     /locus_tag="ACL3GT_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HGR0516013.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNSIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(82078..83361)
                     /gene="tig"
                     /locus_tag="ACL3GT_000285"
     CDS             complement(82078..83361)
                     /gene="tig"
                     /locus_tag="ACL3GT_000285"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HGR0516014.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
BASE COUNT        24645 a        18638 c        15594 g        24692 t
ORIGIN      
        1 tattcgttgt tgttcggata gtggggggag agcaattaat aatagattaa aattataatc
       61 attgattgca ggataacttg ttccagtaga tttattatta acacgattga taaaattatc
      121 tgataataaa taatatttca aatatgtttc gttaagtaaa gtatccaaaa caataaatgc
      181 tgtactagct atcaaatact ctttaagttc tctaactaca gcaatatttt ttagatatgg
      241 tctaactgtt gaaaataaga cactattctg cgaaactaat tttctagcac gggaaggcgc
      301 ttgttcaggt gaaagatatt gtagattttt gtagttgatt atgttctttt ttctatcaat
      361 actagacgta tctatatacc taaaggattt ctctggctta ttttgcccaa aattccaata
      421 aattgatttt atcctcaccc actcccaagt atcaggaata tcataaggaa catcaatttc
      481 ttgagtactt ccatcagcaa acttcccata atgtttctta tgtgcttcaa gtatataaaa
      541 aggcgtaaaa atacgcctat agataatggg gttgaaatag gtttattgtt gatgagattg
      601 tagataattc aattttttac ttccaatcga atattcaaaa cctccacctt ttctgcctgt
      661 aattgttcat cataaaattc aatatcttca ggattttccc cttggcaacc tcggcagaaa
      721 tattcttccg ctcgatcagg attcaaaaat cgacaagcac aaacaaaaca gtcgccatca
      781 tcatttattg agataatata gtagattgaa ataagatgta aacaaatcga ttaggaaagt
      841 taaattagtt tctagaaatt tttagcagat gtagtgtact attctagtct caatttacta
      901 tggcttcaaa tatatctttc gaaaaaatat ttacagatgt gtaattttga agcttgcaaa
      961 agttagtaaa cttgtagatt tcgatttgaa gtaacttgtt ttcttgcccg atattgtttt
     1021 tgaaattgaa tttttccata gtgactcctt aattttcttc tacacgtctg atgataaatc
     1081 taattcgcaa aagagtcaag aggatttttc gaaaaataaa tagcgaccga aatcgctatt
     1141 ttaagggtta taggtatttg atggcttaga ctgctgtgtg actgtttacc cacaggcaat
     1201 ctttcttcta tattagtatt agtaaaggtc taaataatta tcaatttccc attgtgaaac
     1261 gaaggttgca taacttgccc attcgattcg tttggcttca aggaagctag tatagatgtg
     1321 atctccgaga gcagctttaa ccacttcatc ttctgtcaaa gctttcaaag cgttgtgaag
     1381 agttgatgga aggtctgtaa taccagcttc cttgcgctct tctgctgtca tgatgtagat
     1441 attttcttcg ataggagctg gtgcttcgat tttattttca ataccataca aaccaacttc
     1501 caaaagaaca gccatagcaa cgtaagggtt cgccattgga tccactgaac gcaactcaag
     1561 acgagttccc ataccacgtg aagcaggtac gcgcacaagt ggcgaacggt tacgaccagc
     1621 ccaagcaatg taaacaggcg cttcataacc tggaaccaaa cgtttgtatg agttaactgt
     1681 tgggttcatg atggcagtat agttgtaagc atgcttgatc aaaccgccta ggaaatggta
     1741 agctgtttct gacaactgca ttccttttgg atcatttgga tcaaagaagg cgttatttcc
     1801 ttctgcatca aacaaggaca tattacagtg catacctgag ccagcaatac caaattttgg
     1861 cttcgccata aatgttgcgt aaagtccgtg tttgcgagca atggttttaa caacaagttt
     1921 aaagatttga atcttatcac aagcacggag aacttcatcg tacttaaagt caatctcatg
     1981 ctgtccaacc gcaacctcgt ggtgactcgc ttctacttca aatcccattt tggtcaagac
     2041 attcacaatc tcacgacgtg tgttgtccgc aaggtcagta ggtgccaaat caaagtagcc
     2101 acccttgtca ttcacttcaa gtgttgggtc cccattttca tccaacttaa ataggaagaa
     2161 ttctggctct ggaccaaggt tgaaggattt gaatccaact tcttccatgt gacgaagagc
     2221 tcgtttcaaa ttaccacgag ggtcacccgc aaatggttca ccttctgttg tataaacatc
     2281 acagatcaga cctgcaacac ttccattttc atctccccaa gggaagactg tccatgtatc
     2341 caagtccggg tacaagtaca tatccgactc attgatacgt acaaaacctt caatagaaga
     2401 tccatcaaac ataaccttgt tcgacaagac cttatctaac tgttcatctg tagcaggaat
     2461 ttcgacgttt ttcatggttc ccaaaatatc tgagaacata agacgaataa aggtaacatt
     2521 tttttccttg acttcacgac gaatatctgc agctgtgatt ggcataagtt ttctccttaa
     2581 tctatgacta cttgcggttg cctaaccgcg accaaaaggt gactgtactg aagcaaaacg
     2641 cccctgttgg aggagttcat tgtgaagtgc acgacgtact tcagtctgac taaccgcttt
     2701 cttggatttc gcttcacgtt cagcatattt tttcttaatg gcagcgatat tataaccttc
     2761 agagatataa tctttgattt caagcagacg atccatgtca ttcaaggaat acatgcgacg
     2821 atttccttcg tttcgatcgg gcttgatcaa ctcttgattt tcataataac gaatctgacg
     2881 cgccgataga tcggtcaact tcataacact gccgatagga aaaacagcca tatttcggcg
     2941 aaattctttt tccttcattt acaatttcct tctttctgtc tattatagtc taaaaaaaga
     3001 caaacgtcaa ttaataatgt tataaaatgt aacattattt ttcttttttc tctaaaaaga
     3061 gacgaatacg atcaatatcg taatttacga taattgcgac aaaaactccc ataaatgttt
     3121 ctaatacacg cacaaacacg tacaaaattg tctcaccact tggaattgat agggtaataa
     3181 ttaacatagc tgctacacca ccaataaccc ctgctttgtt attcatggct acatttgtca
     3241 taatggttaa catggtgcag attggaacaa ctaccaaggt cacccaaaag gcttcgtgga
     3301 aaaaggtatt taataagaag aagaccaagg catagagtcc accgatacta tttcctagaa
     3361 tacgcgaagt cccaaaatga acactctcat caaaactctc cctcaggcta aaaacggctg
     3421 tcaaagcacc aatttgaaga cctttccagc caaaaaagcc aaaaatcaag agaactagaa
     3481 aaacagcaat acctgtttta aaggttcgca taccaagttt gaactgggat ttatcgaatt
     3541 tatatttttt aaaataactc ataatctcaa ctttctattt ccattttatc ataaatcggt
     3601 gatttttatg agtaatagtt gagaggaagc gtttttattt taagcaaaag aaaagaggaa
     3661 ctttcatccc tctcttcttt gatttgttta taaaatctta tttttctgtc aaggctacaa
     3721 gtcctggaag aaccttacct tcaagaagtt ccattgatgc tccaccaccc gtactaatcc
     3781 atgagaactt gtctgcacgg ccaaggttaa tcgctgcggc agctgagtca ccaccaccga
     3841 tgattgattt aactcctggt tgtttcacga tagcgtccat cacaccgatt gtaccagctt
     3901 ggaaatctgg gttttcaaat acacccatag gtccgttcca tacaactgtt ttggcaccag
     3961 tcaaagcttc gtcaaatttg gcgatagatt ttggaccgat gtcaagacca aggaagcctt
     4021 cagaaactgc ttcaccttca gtgtcacgca cttcagtgta accagcaaat gcgttagctt
     4081 cttttgagtc aactggcaag atcaatttac catttgcttt ttcaagaaga gctttcgcaa
     4141 catccaattt gtcttcttct acaagtgagt taccgatttc gataccttgt gctttgtaga
     4201 atgtgtaagt catcccacca ccgataagga ctttatcagc tttttcaagc aagttttcga
     4261 taacaccgat cttgtctgaa acttttgaac caccaaggat agccacgaat ggacgttctg
     4321 gagtttcaac tgcttcttgg atgtaggcaa tttcgttttc aagaaggaaa ccagcaactg
     4381 ctttttcaac gtttgctgag ataccaacgt tagatgcgtg tgcacggtga gctgtaccga
     4441 atgcatcgtt tacgaagata ccatctccaa gtgatgccca gtatttacca agttcaggat
     4501 cgtttttaga ttctttcttg ccgtcaacat cttcgtaacg agtgttttca accaagagaa
     4561 cttgtccatc ttcaagagcg ttgattgccg cttccaattc agcaccacga gtgacacctg
     4621 ggaaaacaac atcttgacca agttttgctg ccaagtcagc tgctacagga gcaagtgatt
     4681 taccagcttt atcagcttct tctttcacac gtccaaggtg agagaaaaga attgcacgtc
     4741 caccttgttc gatgatgtac ttaatagttg gaagagctgc tgtgatacgg ttatcgttag
     4801 tgattacacc atctttcaat ggtacgttga agtcaacacg aacgaggact tttttacctt
     4861 tcaagtcaac gtctttaaca gtaagttttg ccatgttaca aaaactcctt tatttatttt
     4921 attcgaaact attatatcac actttagaaa tataaggaaa gatttcacaa gatttttcga
     4981 tatttaatct ttatcttctc ttttccgtct caaggtcaag gctaaactag caagaccaag
     5041 gctggctaag cctgctatta gggcttcatt agcatcagct gttcctgtat ttggcaattg
     5101 tttgcttgct tcttctgatt taactgctgt attttgagct ggtttttcct gtgtagctac
     5161 tactgctggt actgttttta cttttgttcc aatttcaaca atttctggaa tcgcttcttg
     5221 gatgacttct gttgaacgaa gacgacgctg accgttttca tcaacttcaa agacatgtct
     5281 taacagtcca tctcgtccct gtatgatgac tcgttgttcc ccaactagca tctcagcatt
     5341 ttcatgctct tgacgatgaa aggcaacctt ttcctcttga acttccaatt taggagcctt
     5401 ttgttgatca gaagccggtt gataagtagg ttttggaagg actgtgtttt gtggtgctgg
     5461 tttagcaggt tgtggttttt cagcagattc ataaacaaag gcataatgag taaagtgagg
     5521 tgctgtaaag ataacatgac tatccgtttg ttcaaaagcc aattctactg cctctttgcc
     5581 ttcaggtaag aaaaatactt tcttaacttt cttatctttt tcaattggga ttttcacaat
     5641 agaagcataa gagagatcaa catcttgacc tttttcatcc aaaccttcta tttcaaagac
     5701 atgagcatct tctccagcaa agtatttctt ctcttcagca cttgcttgaa cacgctctac
     5761 tttcaaaccc ttgatgacag tcttctcttt atttgagaag tgtacttcaa cacctgtttt
     5821 actatcagaa aagactgctg gcttgtcttc tttcaataaa gcaaccagat cttttagact
     5881 ctgtttcgct gttgcaagct cttctggact caaatctact ttttcaacca aggccttgtt
     5941 tttctcaaga agcggagcta gggcagaacc tgaaggatgg tttggtttgg cagccaagag
     6001 ttcttgaacc tcacctgtta aacgatcaag ctctgtcttt tcttccttaa atttctcttg
     6061 accattcaga gctttatgag cttctgtcaa tttattaagt cggtcattga cttgatcttg
     6121 ggtgctagtt tcatggtctt tcaacacttg ttcggccgct tcaattgctt tcaagaaagc
     6181 ttcttttact tctggtgaag caaagttata gaccaccttg ttcttagcag cttcaacttc
     6241 tgctaatttt tgtttgaggt actcatcgtt caatgctgct tttggagata ccaaaacatc
     6301 aaagttgact tcatgacctt ggtaacgaag cgtcaaggtt tgacgaccag tcttttgagc
     6361 atcgtaacca gaaatttcaa ctccctcatc agtaaaggaa tgttcttcca tggtgtcatt
     6421 gctataagcc actgcaaagc gtccttcaga caagtctaag ctatcaccaa ctaggtaatc
     6481 ttttttcggt tcctgactta cttcaattcc caaaatagtt ttcggacttg cttcgtcttg
     6541 gccagtgaca gtcactgaca aattagcatt tactggttgt cccaaatatt ggagagtaag
     6601 attctgttct cccttatgat gcgtatcaaa acctgatact gatacacctg cgtgagttag
     6661 gcgaatgagt tcgtcctcag ttcctccttc atactgaact cgaagaacac cacctctaag
     6721 gtccaaatcc tccccttcgg cgtagcttgt tttcttaggt cctgtttcta ggctgactga
     6781 cttgattctt ctgtcatctt ttggaacgga aactgctagg acattactaa tttccttgcc
     6841 tggcaactgg gtacgataat aaagaagacc agattgattt gtcaaatcca atggtgcact
     6901 tgctaggtct cctccaactt cgctcttcaa ggttgcgagt ggagtttgag aatttggatt
     6961 atcataaacg gtaatagttg ctccagccgg tacatctgca aagccaactt gtaccttgtt
     7021 attgcctaga gaacgggctg cagccttggc catcggaata ttgacactct cagtatcaag
     7081 cttttcatac attttccagt tatagatacg aatagccttc catggagttc cattgtcaga
     7141 agtgacaaca ttcaagcgcc agtcttgagc agtgattggt ttatcaagag tgatatctgt
     7201 cacgtgtgct ttgttgccac ggacttcctt agctagcttc cactcaccat ctgcatcttt
     7261 ataataaagg tcaaagtctt tggtgttcat caagccatcg ttaacagact caccaccagc
     7321 ccctgcatga tccatgaccc atctaacaac ggtacgtggc ttggtcaaac gaatatccac
     7381 actaccactc aactgagctg aagaccattt atctgacaag ctagtaatgg taccgttcaa
     7441 cataccttca ataccttctc caccttctgt atctgggaag gtacttccga taacagtagc
     7501 ccctggaacg atgttttctg ctagaggtct tggaagactt gtgtcttgga cagtcatccc
     7561 ccactcaaag gttgtggttg cagcttctga acgaactcca tttttaccga ctgctacaac
     7621 cttcagttct tgagttgtac cctgagcact tgctgagcgg ctaacttttg gtagataaat
     7681 agttgtagaa gatgagccag ttagtaattt ccagctgtct ccatcttttt cataaacttc
     7741 atagaaatct gcatccttgt tgcctttaaa ttgcacaact gcttccgctt cttgggcatt
     7801 tttaagagat tgtttcacta cagaaaagct tgtcggcgat tgtggctctt ggtgattgtc
     7861 cgagatagtt aattgtccta ggttgaaccg ataatctttt acagcacctt catgctcgaa
     7921 aaatagtttg actgcataga tggttttacc tgctagtgag ctgagatcaa attcttcatt
     7981 tgtccagttg tcagaaaggg ttagctcttt ccatgcatct gcatcatcga atttgtagtc
     8041 tggagttgta gagaatgcca tataaacttt agaacctttt cctcccttgt gggcaacacg
     8101 aagtttggtc ttctcagtta cttctaactt agtagaataa agtctcacat cctgatctgt
     8161 cttaccggct acatcaccag agaatttaag ggaatttccg ccattatagg catctgtaaa
     8221 atcatattct gcacgaagtt tttcccctgt tgaagtctgc caccagcgcc atgttggaag
     8281 aacacctgat actgaacgat aattccactc agaatcctta gaaaccttac catctacgaa
     8341 ccatttttta ccatgacctg tattaaaaga agtagtaaaa gtattaccta ccgctggcgt
     8401 acggtccgca actaggttag caataccata ccaatctttg tcacctggtt tttgaccagt
     8461 agggtctcct tgataacctg taaagaagat atcttcattt ttatgataat cttcaccagt
     8521 ttttcctaaa cttgtaatgg tatctggggc aaataaacca agagaaaggc gcaatttccc
     8581 attttcgtct aaaatgtcat tccacttaac ctttgtcttg taggaaccac cctgttgcaa
     8641 ttccaaacct gcaaatacat cataaggatt acgaccaatc cagttggcag ttgcaatagt
     8701 gtaatcattt ttagccttat cccagttaaa gttagcaaag aagttatctg ccggaacctt
     8761 atctccttct ggttgcatga attggtagtt gtattctccc aaaccatctt gatggtaacg
     8821 tccatagtta taggtcatgg catcatacca agaatacttg attggatggt ttaccttagc
     8881 agcatattcc ttgctataga gcataaactg gcgcatcttt tctccaagag gtttaaccaa
     8941 atctccagtt gtttcttggt tgatgaaata gccatcatag ccataatact tggccatgtc
     9001 taccaattta cgggcaattg ggaagctacc atctgcgtct tgcttcaaag cttcagcaaa
     9061 tctttcttga tctgcaatac tattagacca gttgaagaag agtgtaccgt atacaggaac
     9121 cccgttacgg tgacctgcat caataacgtc aggagttggt acgagacctt cccagaagac
     9181 cattgaatct agatattgcc aatagtcaaa agcataggcc ttgaactctt ctccaccaac
     9241 agaagcatgg tcttttgctt tagaattggt gtttgataag gcttgaactt ttgcttcctt
     9301 gctagctttt tcattgacta aatgacctgt ccgacgtgaa gcgaggacaa cagatccgcg
     9361 gttaatagca tcatcttcac gagcacctgg ttcccatttt aacaattctt cccaagaatt
     9421 aaatttgatt tcctttggtt ttaatgtttt ttctgtattt ttagggacat ctggctggac
     9481 ttctttttca gtcttattag cttctgctgc tggcttagac tcatcccctt ggttagttgc
     9541 ttcgggcttt gcttctgttt ccttgtcaga cttaggtttt gcttctgcag atggtgtttc
     9601 tgcaaccacc tcacctgctt tttcctctgg tttagctgcg ctagctgctt ctgccttttc
     9661 tagcttgttt tctctagcat gttccccttc attctgctta tcagcttcat tggtcgaatg
     9721 ctcactctct cctgaaacaa gctctgtatt agctccgcta ttttcaggaa ctgcagtttc
     9781 ttcagccaag gctggaccag caaataaaac agcaccaatc atcagcgagc aggctcctac
     9841 tgataactta cgaatactgt aacgacaacg tctttcaaaa aatggattct tcattttctc
     9901 ctcctaaaag attgattttg ttgttttaaa gaaagcgctt tatattctgt agttttttat
     9961 caaactctag aaccatgata atcacatttt tatcctaaaa catttttaga caaaaaacaa
    10021 taactgtttg cacaaatcta aaataaggtt aaaaactctt aaaaataata cacttatcaa
    10081 ttataatttt cttttacaaa cttgacatta acacttgtta gatttacttt tatcctttaa
    10141 aatagaatag gagatattcc gcgattattt ttcggaggaa aaagaaatgt ccattaattg
    10201 gcaggaaatt ttatttcact ttttaggtgg tctggggcta ttcttatata gcatcaagac
    10261 catgggagac ggtttgcaac aagctgctgg agatcgcctt cgtttttaca ttgacaaata
    10321 tactagtaat cctttctttg gagttctggt tggtattggg atgactgctc taattcagtc
    10381 tagttctggt gtaacagtta ttacagtcgg cctggtcagt gccggtctct taaccttacg
    10441 tcaggctatc gggattgtca tgggtgctaa tattgggaca actgtcacat cctttctcat
    10501 cggttttaaa ttaggtaact atgccctacc tatgctcttt atcggtgccg tctgtctctt
    10561 ttttacgaaa aatcggacag tcaataatat cggacgcatc ctctttggtg tcggtggtat
    10621 cttttttgcc ctcaatctca tgagcggcgc aatggctcca ctcaaggatt tacaggtctt
    10681 taaggactat atgattgagc taagtaagaa tcctgttttg ggtgtctttg tcggtaccgg
    10741 cttgaccttg ctaattcaag cttcttcggc taccattggg attttacaaa acctctacgc
    10801 cggcaatcta attgacctac agggagcttt gccagttcta tttggtgaca atatcgggac
    10861 aaccattaca gccatcattg cctctttagg ggctaatatt gcagctaaac gggtagcagg
    10921 agctcatgtt gccttcaacg ttatcggaac agtcgtctgc gttatttttc tagttccttt
    10981 tactgtcctg attcattggt ttgaagctac gctaaatcta gcaccggaaa tgaccatcgc
    11041 ctttgctcac ggaaccttaa tattaccaac accattgtcc aatttccatt tatcggagct
    11101 ctggcttact ttgtaaccaa gattattcct ggagaggacg aggttgtcaa atacgaaccc
    11161 ttatatcttg atgaacattt catcaaacaa gccccatcta tcgctctagg aaatgctaaa
    11221 aaagagctct tgcacttagg aaactacgct gctaaagcct ttgacctttc ctataagtac
    11281 atcattgact tggatgaaaa agttgctgaa aaagggcata aaaccgaaga agcaattaac
    11341 accatcgatg agcaattaac acgttatctc attgcccttt caagcgaagc tctcagccaa
    11401 aaagaaagtg aagtgctcac caatatcctt gattcctccc gtgatttgga acggattgga
    11461 gaccacacgg aggctctact caatctgact gactatcttc aacggaaaaa tgttgaattt
    11521 tctgatgccg ccttgaaaga attagaggaa gtttaccgcc aaactagtga ctttatcaaa
    11581 gatgctctgg atagtgtgga aaacaatgat attgaaaaag cacgcagtct tgtagaacgt
    11641 catgaagcaa tcaataagat agaacgtgtt ctcagaaaaa cccacatcaa acgcctcaac
    11701 aaaggcgaat gttcaacaca agctggggtc aactttatcg acatcatctc acactacact
    11761 cgtgtatcag accacgctat gaaccttgct gaaaaggttt ttgcagaaca aatctaataa
    11821 ccaagaagct atccatcata attggatggc ttcttacttt ttcctaagca agactaggct
    11881 gaatgaaact gaaagagtat tctgcagata tatagtatat tgaaactaga atagtacacc
    11941 tctatttcta aaacattgtt agaaatcgat ttgactgtcc tgatcgattt gtcctgttat
    12001 tatttcattt tactatagtg gattaaatta aaaaagtata atgtattgaa tctataacag
    12061 tacatcttga ctgctaaaat atttctataa attaatttga ctttccttat agagatgttc
    12121 acatcttatt tcaattcatg atacaatcca gttcctaaaa ctttgctaga aattaatttg
    12181 gctttccgaa ttaatttgtt cagattttat ttcatttcaa tatactgata aatccattca
    12241 ctagcacagg gcaagaggga gtcgctattg atttcaacgg tagcaggtac atacagagga
    12301 ctcctacctc agatatactg caatatcatc gtatgcaaaa aacctctgag atttttctca
    12361 aaggttctga ttttgctaat tgctgttctc aaccgctgca gtaacaaagg cagtgtagag
    12421 ttcttctggt cggtttggac ggcttgacag ttcagggtga tactgacaag ctacaaagaa
    12481 tttattttca ggaatttcca cgatttctac caaacgattg tctggagaaa ctcctgaaaa
    12541 gacaaaacct gctgcctcaa actgctcacg gaaggcatta ttaaactcat aacggtgacg
    12601 gtgacggcgt tgcaccactt cttgattgtg ataagcagca gcagccttag agccacgttt
    12661 caacttagac ggataaagtc ccaaacgaag ggttccaccc atatcctcaa tatcaatctg
    12721 atcacgcatg atatcaatga tagggtattt tgtttctggt gcaagctctg cagaattggc
    12781 accttcaaga cctaaaacgt gacgagcaaa ctcgatacat gtcaactgca ttcccaagca
    12841 gactcccaac attggaacat cattttcacg cgcatagcgg atggcttgga ttttcccttc
    12901 tgtaccacgt tgaccaaaac cacctggtac gatgatcccg tccgcatcag acaagagttc
    12961 tgctacattc tctgctgtca catcattggc attgacccaa ttgattttaa cttctgtatc
    13021 attgacatag ccagagtgtt tcaaggcttc gaccactgag atataggcat cttgcaactc
    13081 cacatactta ccaacaaggg aaatcttaac ttgtttcttg aggttcatga ccttgtccac
    13141 catggctgac cattctgtca tagccgctgc tggtgcgtct aatttcaaat gatcacaaac
    13201 aatttggtcc atcccttgtg cctgcaagtt cagtggaatt tggtaaaggt gttcaacatc
    13261 caacgattcg ataacggctt ctggtgccac atcacagaac tgggccagtt tatttttaat
    13321 tccttgacca gctggctctt ctgtacgaat aaccaacata tttggttgga ttcccaagcc
    13381 acgcaattct ttgacagagt gttgggttgg tttggttttc atttcaccag cagccttgag
    13441 gtaaggaagc aaggttgtat ggatatacat gacattatcc gcacccacat ctgccttcat
    13501 ctgacgaaga gcctctagga atggcaagga ctcgatatct cctactgttc caccaacctc
    13561 tgtgataatg acatcagagt cggtcgttag agcggcacgc ttgatttttt ctttcaaagc
    13621 atctgtgata tgaggaatga cttgaacagt tgccccaagg tattctccac ggcgttcttt
    13681 acgaagaact tcactgtaaa ttttcccagt tgtcacgttg gaatatttgt tgagattgat
    13741 atcgataaaa cgttcatagt gacccaagtc caaatctgtc tcagctccgt catctgtcac
    13801 aaaaacttcc ccgtgctggt aaggactcat ggttcccgga tcaatattga tataagggtc
    13861 aaacttttga atggttactt tgagaccacg atttttcaag agacggccta gactcgctgc
    13921 cacaatccct ttcccaatag acgataccac accaccagtt acaaaaatat atttcgtaga
    13981 catagattcc tctttctaaa atgctcaagg tcttgttaac tacgagggga tatagaaaac
    14041 aagaccctac taataagaat aatctgggac gactgcacca gattcacaac taatactctt
    14101 cgaaaatctc ttcaaaccgc gtcaacgtcg ccttgccgta gatatgtgtt cctgactttg
    14161 tcagtcttat ctacaacctc aaaacagtgt tttgagcagc ctacggctag tttcctagct
    14221 tgctctttga ttttcattga gtataaaata caagaagata acttcttgaa aaaacaaaaa
    14281 tagctcccta agaactaggg agccccgacc tctaaaagag gtgcccaaac aatatgatac
    14341 ctaaaaatag gataattgtc aatagctaac tcttattcct cgctggtttc agcgtcgtca
    14401 tctgaaaact cgtcgtcgtc ttcgttgaga tccacatctt ctcccaagtc atctggagcg
    14461 atttcgttga tttctgcatc ataagcttcc acttcatttt tttcatcatc tggattttca
    14521 tcatcgtatg aaagagctgg atctgcttcg tatgcatctt cgtcttctgg atcatctgca
    14581 ttgtagtcaa tggcatctga atcaccatcc ataaaggcat tgacacgttt tttcttagct
    14641 tttggtgcta cttcatcgtc gtcattttct tcaagagcga tgatttcttc gtcgatttcg
    14701 tccacaccat accatgaacg aagaccccat ttgttgtccc caagtgagat gaagctaccg
    14761 tcaaagttca actctgtgta gaacagaggc aaagcttcgc ggatatcgct gtttgatgtt
    14821 ccaaggtagt tttgaatttc gtttacaaga tcgctaaaat gcatctcatg atcgcgacca
    14881 cgaagttcta atatagcacg cgctacctca atcatagata gttcactttt ttcttgccca
    14941 gcaaatactt ctaattccaa agcgtttctc ctcatttata ctactatcgc cagagcgaac
    15001 agactctgac ctcattttat catttactct ttattttacg ataattttgc ggaatagtca
    15061 aaggttaagg gggagaaagt ggcaggatta gactaattcc aatataaaac tccttccttt
    15121 ttctgttgct ccattttcca caaatccaag cgacttgaaa cacctcctag aagcatgatt
    15181 gtaggtgtag atttccttga ctctcaattc tttccatcct tttactcgag ccaattcaat
    15241 caaagcactt agaatctttt ttccaagtcc tcgatgttgg taagcggaat tcccaatcac
    15301 aatggggaga ttatcctgag atagtgtaat atccccaatt ggaaaccatt ctcccttctc
    15361 cttgacttca atccaaaaaa gctcaccatg ccgatccaaa taggaataca tggcttccaa
    15421 ggtcgcttga ctgtaaggaa gcttcacccc atctacgagg taaaccaagt tcacatcctg
    15481 ataccaagca aaagcttcct cacaatgatt gaccttataa taaggaacaa aacacaatgc
    15541 actacctttt caacaaaaga gttgctgctt gattaaaacc atcacaccag ttataccatt
    15601 ttgcttcata cccatcttga gctaggatac gatcttctaa atcaaaaaca gagtaaatct
    15661 ttctttcctc gcaagcttgc gcatagagat gatatagttc atcaccacca tctctatccc
    15721 actcagcaga aatcgtatcc cgatctgcca ataaagtctg ataagccctg tgatgcccat
    15781 ctgtaatcag caaacaatct ccaaaggcaa gaatactgat tggatcgact tggattgttt
    15841 ctgccgactg gtaaagcatc tgaatatctt gcaacttctt ttctgataaa tatagttgag
    15901 tcggatgaag atctgctatg ttgactttca tttctttctc ctcaagggaa ttcgatactc
    15961 acttctgttt gcctttaaat cgccattgga agcggagctt gtcatagaag ggaaactcga
    16021 taaacaggac tcccaagccc acacagagac tggcaaggac gtctgatggg taatgaactc
    16081 ccagatagac tcttgatacc agcacactga ctaggtagag gccaaggacg atttgtacga
    16141 tttttctcca gactggatct ttaatccgct gactaagaat aacaatcaaa gtacctacca
    16201 tcaaggttac agccagagaa tgcccacttg ggaaggaaaa tcccttctcc tccaccagat
    16261 gtaagatatc tggccgtggg cgctggtaga tatttttaaa ggtcacgatt aaaagacctg
    16321 ccaaagccag atttcccagc atgaagaaac tttctatctt ccatcgctta cgataaaaga
    16381 caaaagctgt aatgacaacc caagtgataa tcactgggat atcaatcaga cgtgtgaggg
    16441 ctcgaaaaag aatagtcaaa taatctggta agtctcctcg aatggcagtc tgaatcgatt
    16501 ggtcaaaatt gaccagcgtt tcagggtaaa atttgaccat gtagccaaga ataacgaaaa
    16561 gtaaaagggc aaaactgccc ttcattaaaa atgtttgttt atctctcata atgttttaag
    16621 gttggtttca agagaacata caacaaccag aatgaaacgg aaaagataac accttcaatc
    16681 aagttaaaag gtaataccat ggtcattagg tagttggaaa gtcccaaaat ttttccaata
    16741 tcaaagttag caaacttagc gtacaaagga acagcataaa catagttgag aaccaacatg
    16801 gccaaggtta aaccaatagt tccagctaga gagcctagta ggaaacgaag ggttgtccgt
    16861 tcctttttcc aaatcaaagc aaatacgatg acaaaaactc ccaaagctac gatattcatc
    16921 ggcaaaccaa tgtaagtatt cactccttgg ctgttaagaa gcaacttcaa gagtgagcga
    16981 agcaagagca ctcctagagc agcaggcaaa tccatgacca ccagacccac aaggactggc
    17041 aagatactaa attcgatctt gaggaaagat gccgctggta aaagcggaaa atcaaagtac
    17101 atcagcacaa atgagatggc tgatagaatt gcaatggtcg aaagtcgacg tgtgtttgtc
    17161 ataacaggtt cctccaattt tctataaaat cagaagaagt tggaaaggat tcctctatct
    17221 attctcactt tttatatccc aaaagttccc tcttactcta ttaaagaaaa acaaagcaag
    17281 tggttacaat ccggctataa atctatcaaa acagacaaag ctattctttc gtcttctccc
    17341 atccagacta tactgtcggt tgtggaatct caccacatca gcttgcgctc gcggacttct
    17401 ttaaagggaa agaaatagag atttttcttt tagactaggc gacaagctgt aggcataact
    17461 tctggttagg caaagcttgt caacaaagta taaaaggaaa agatcatttc ctagttaaag
    17521 tcaccgccgg tcgggaatca caccctgccc tgaagactct tttatcataa caaaaaacgc
    17581 ttgcaagcgc aagcattttg ttcattttca ttttttattt caatttatcc acttcatagg
    17641 tatggacgag ctcaagacct gcaaagttct gctggcgaag agcctcatag acaatcatgc
    17701 agacggtatt agacacattg agactgcgga catgttcatc attcatggga atacggagag
    17761 ccttctcagg atgttctcgc ataaaatctt caggtaagcc cttgtcttca cgtccaaaga
    17821 gaaaataatg gtcctcgtca gtcgataaat ccacctcaga atagattttt tccgcgaatt
    17881 tcgaaatcag atagagtttt cccttcatct gagatatgaa atcttctaaa ctctcgtaaa
    17941 aataaatctc tagcttatcc cagtaatcca atccagcccg cttcatcttg cggtcatcaa
    18001 taggaaagcc cataggcttg atgatgtgga ggggagaatt ggtcgcagcg caagtacgcg
    18061 cgatattgcc tgtattttgt ggaatttgag gttcaaataa tacaatgtga tttgtcatga
    18121 cttgcttcct ttcaccattg caaaaaaata gccacactgc ccggagtcaa gctcagcaaa
    18181 cagcgtggtt aaggcatcgt taacttacct cacaacaggt ttgaagtaaa tcagcgaaac
    18241 tactttctta gtataacact ttcagaatca ttgtcaatag aaatgacttg attttttcaa
    18301 ttttttcaag ctatttccaa gggttgtaaa atcgtccctg attctgcaag ataagtagta
    18361 aactaactac taaaaacaag gttgccaaga gcaaggtaat atagtctcct tttttcaagg
    18421 cctgataact ataccatgtg cgttttttct ctttcccaaa gcggcgaagc tccatggcag
    18481 tcgcaatggt atcaatgcgt tctagcgagc taaaaatcaa gggcgtaata atgagcagat
    18541 tgcctttgat tcgttgcata agagaagctt tcttggataa ttccatccca cgcgcctcct
    18601 gagacatctt gatagtaaag aattcttcct gcaaatctgg aatatagcgc aaggtcaggc
    18661 tgacagaata agcaatctta tagggcacac caatttgatt taaactggaa gcaaactgac
    18721 taggatgggt tgtcatcaaa aagataatag ccagaggaat ggtgcaaaga tacttaatgg
    18781 ccaaatttag cagataaaag agctcctggc tggttagagt gtagacaccg attccctgcc
    18841 aaatcacact tctctctcca taaagtccaa ccccatactc gggagaaaag agatagacca
    18901 tcaaaacgtt taaaacggca aataccgtcg caaaaacggc tacaaaggaa acatctttaa
    18961 agcgaatttc tgataaatag aggagaaaga ctgaaaagat ggcaatcagc aagagcattc
    19021 tggtatcata gctaatcatg gccgccaatg ataccagaat gaaaaagaga agtttcccag
    19081 ctcctgacaa gcgatgaatc acagtatctc tatgctggta accgattaat ttagcttgca
    19141 tccctctctc ctttctttgt aaaatgccgt taaatccagt ggatccacat ctagtttctt
    19201 agccaagtta aagatggagg tttcttttag attggctttt actaacagct caggatcgct
    19261 caacagactg gctggaacag tatcggcaat caattctcca tccaccatga caaggacccg
    19321 gtctgaataa tccagcatca attgcatatc atgggtaatc atgacaatgg tatgcccttt
    19381 ttgatgtaac tcttcgagaa attccataat ctcagtatag ttcttctgat cttgacctgc
    19441 agtcggttca tctaggagaa taatttcagc tcctaagacc aaaattgaag caatggtgac
    19501 acgttttttc tgaccaaatg acagggcaga aataggccaa ttacggaatt cataaagtcc
    19561 acagattttc aaggtttcat agactctcgt ttcaatttcc ttctcatcca cacctcgcaa
    19621 acggagccct agagccacct catcaaaaat catattggtt gaaatcattt gattaggatt
    19681 ttgtagcaca tagcctactc gttccgcccg ctctgcaaca gaatcgcctt ttatatcctg
    19741 tttttcccaa agatagcgtc cttccgtctg aataaagcta cttatagcct tggctagagt
    19801 tgatttccct gctccatttt ttccgacaat agcaatcttt tcaccctttt taatatctaa
    19861 atgtagggat tttaaaatcg gtctatcatc ataagagaaa gacacgtcct ctaatttaaa
    19921 gagtgactgc aattctggag tttcttttgc cagttcattc tgcagctgaa cctgaccttt
    19981 tgagatagac atgttatcca gattcgctaa ctgttcttcc ttgactaagt ccacacctaa
    20041 ttgacggaga gtcgttagat aaaggggttc tcgaattcca ttttgagtca ataaatcagt
    20101 cgcaagcaac tggtcagggc tcccattaaa aaggatacga ccatcgctta tcaagacaat
    20161 ccgatccaca gggcgatgca gaacatcctc caaacggtgc tcgataatca gagtcgtcgt
    20221 cccctcttcc ttatgaatct ggtcaatcaa ttcgataata tcctgacctg acttgggatc
    20281 tagattggcg agtggctcat caaacaagag aatcggactt tcatcaatca agacaccagc
    20341 cagactgact cgctgctttt gtccacctga caaatcctga ggacgctgat ccagtaaagg
    20401 aagaaggtcc agcttttcag cccatttata aacacgacct ttcatctcat ctagggctgt
    20461 cacatcattt tccagagcaa acgccaaatc ttctgccaca gacaagccaa taaactgccc
    20521 atctgtatcc tgcaaaactg tgctaaccag atgagactta tcatagatgc tcatatcaaa
    20581 ggctacttga ccctttatca aaaattctcc atatgtctga cccttgtaaa tattgggaat
    20641 aatcccattc aaacactgac ccaaggtaga tttacctgac ccagatggtc caacaattaa
    20701 gactttctct cccttgtaaa tggtcaagtc tatcccttgc aaggtcggtt cttgttgtgt
    20761 ttcataccgg aaagagaaat ccttccactc aattatagct tctttcatct tactctcttc
    20821 attcgcttct tagacttcta ttttatcata aatcaagccc ttcttgcagt ctcttctctt
    20881 aaaatcttag cgccaaaaag attcctatcc tagcttactt gcctaactaa tctataaaca
    20941 tcgaaaaaga ctagttgccc agccttcccc atcattttat actcttcgaa aatctcttca
    21001 aaccacgtca gcttcgcctt gccgtaggta tggttactga cttcgtcagt ttcatctaca
    21061 acctcaaaac catgttttga gctgacttcg tcagttctat ccacaatctc aaaacactgt
    21121 tttgagcaac ctgcggctaa cttcctagtt tgctctttga ttttcattga gtattagtcc
    21181 tttttcaaac ttcctgcacg agtttgggtt cctgcatagg caagtaagag aagagttcct
    21241 gcaatagcta cagatacacc attggcaatt cccgcaacaa tcccttgtgc aaatactttt
    21301 tctgccgctt cttgataaat cacaacatct ccaagtggtg ccaagacacc ccaaacaagg
    21361 gcatttgcaa gtagttgaat gaggttaaaa ataagaatat ctttccagtc aaaaacacca
    21421 ttgatcactc gaacgtactt tctaaaaagt cccacaacta gaccaaagag tccgctagcg
    21481 ataatccaag tccaccatag accataacca gcaagagagt ccttgattgc atgaccaatc
    21541 aacccgacaa gcaaaccgat aatcggtcca aaaataatag aaagtagcgc ttgtaccgca
    21601 tactgaagct ggatgcttgt atttggaaca ggggttggaa tgttgatcat cccgatgacg
    21661 acaaagaggg cagcgccaat tccgacagca acaacttgtt taattgtaaa tttgatttcc
    21721 atactattct cctattttat ccttctattt tctttatttc aatggtccaa gatgaaccga
    21781 cacctacatt ataggccttg gcaaaggaac cttggttgat agccaaacct aaacgataga
    21841 gagagttgat gtaaaggatg ggttgcccaa ttctcacatc tgcaaatgat ttgccataga
    21901 caacctgatt ttgatagacc agcatatcag catgatagat ggtcacttca aaacgatcac
    21961 caaattctgg ttccagcttg taaaattctt cccgtgtgat agaggtccaa agcgaaccga
    22021 aacgcacatc cagaatatca atggctccct tcaccagatg atcttctatg atggtcgcta
    22081 cgactggaag ctctacaatc tgttccacac tgagctctgg ccctacttcc tcaaaagtaa
    22141 tgtgaccact ggccagttta gcaccagtat aggcatagac atcacgaccg tggaaggtat
    22201 aagaatgctc tgtgttttga cgcctattgg ccacctcaga aatctcacga atggctacaa
    22261 tgccaacgtg tttcttgata aaggaaagcg tcccattatc tggcgtgaca atgtattgat
    22321 tttttgcagt cttggcaact acactcttac gtttcgaacc gacacctgga tcgacaaccg
    22381 atacaaacgt cgttccctca ggccagtaat ccaccgtctg aaagagacga tagctcccct
    22441 caaaaatatt ataaggcgtg atatcgtgcg tcaagtgatg gatttttaag gttggagact
    22501 cttctaaagc cactccaatc atagccgaca ccgcaccatc aaccagacca aagtctgatt
    22561 gtaataccag taaattattg ttcattttat ctccttgtat atcctttatc ataccatatt
    22621 tcagagaaag tcgctaatag ctatttcaat tggttagggt atagttttac cttatagcga
    22681 attttcacta aaagctcttg ttattagcta gtaggtgcat tttttcttga aaaagggtat
    22741 gatagttaca tcatgaaaaa gtaggtttta ttatgaaaat tatccttgtc ggagggggaa
    22801 aagttggttt tgccctctgt cgctccttgg ttgcagaaaa gcatgatgtt ttgctgattg
    22861 agcaagacga agctgttctc aatcatattg tcagtcgctt tgatatcatt ggtatccttg
    22921 gtaacggggc cgattttgcc attcttgagc aagccagcgt ccaagattgt gatatcttta
    22981 tcgccctgac tgagcacgat gaagtcaaca tgattgcagc agttctagcc aagaaaatgg
    23041 gagctaaaga aactatcgtt cgggtgcgga accctgaata ttctaactct tatttcaagg
    23101 aaaagaatat tctcggtttt tctcttatcg ttaatcctga gctcttggct gcccgcgcta
    23161 tcgcgaatat cattgacttc cccaacgccc tgtctgtcga acgctttgct ggtggacgcg
    23221 ttagcctcat ggaatttgtc gtcaagtcca ccagcggtct ttgccaaatg cccatttctg
    23281 attttcgtaa aaaatttggt aatgtcattg tctgtgcgat agagagggat catcaaatta
    23341 tcattccaag cggtgacatg actgtacagg ataaagatag aatctttgtc actggtaacc
    23401 gtgtcgatat gatactcttc cataattatt ttaaatcacg cgccgtgaag agccttctca
    23461 tcgttggagc aggtagaatt gcctattatc tacttggtat tctcaaagat agtcgtatcg
    23521 atacaaaagt cattgaaatc aatcctgaaa tcgccagctt ctttagcgag aaattcccaa
    23581 atctctacat cgttcaagga gatggaaccg caaaagatat cctgctggaa gaaagtgctc
    23641 aacactatga tgccgttgcg actctaacag gagtcgatga ggaaaatctg attacatcta
    23701 tgttccttga cagggtaggt gtacagaaaa atattactaa ggtcaatcgt accagtctcc
    23761 tcgagattat caatgcgcct gatttttcaa gtatcatcac acctaaaagc atcgctgtag
    23821 atacgattat gcactttatt cgtggtcgag ttaatgccca gtattcagac cttcaagcca
    23881 tgcaccatct agccaatggc caaatcgaaa ccctgcaatt ccatatcaag gaagccaata
    23941 aaatgactgc caaacctctt tctcaactga aattgaaaaa aggggttctt attgcagcca
    24001 ttattcgaaa gggcaagact attttcccaa ctggggagga tatgttggaa gttggagaca
    24061 agctcctagt aacaaccttg ttgccaaaca tcaccaagat ttatgacttg attgcgaggt
    24121 aagaaatgaa taaaagtatg attcgttacc tcctttcaaa gttacttttg attgaagctg
    24181 ttctcctctt ggttcctgtg gctatcgctg tctattaccg tgaatcgagc caagtcttta
    24241 cagccctctt ttcgaccata gggattctcg tattgttagg cggttcaggg agtttacaga
    24301 agccaaaaaa tcaacggatt tatgccaagg agggagtctt gatcgttgcc ctctgttgga
    24361 tcctttggtc tttctttggt ggtctcccct ttgtcttttc tgggcaaatc cctagcctta
    24421 ttgatgcctt ttttgaaatt agttctgggt ttacaactac tggagcaagt attttgaacg
    24481 acatttcggt tctcagccgt tccctcctct tctggcgaag ttttacccac ttgattggag
    24541 ggatgggagt gcttgttttt gcacttgcta ttatggacaa tgccaaaaat agtcacctag
    24601 aagtaatgaa ggctgaggtt cctggtcctg tctttggtaa ggttgtatcc aaattaaaaa
    24661 acactgccca gatcctctat ctcctttaca tagccctctt ttccctcttt gtcatcatct
    24721 attatctagc cggtatgcct ctctacgata gttttgtcat tgctatgggg acagcgggaa
    24781 ctggaggatt taccgtctat aacgatggaa ttgcccacta tggtagctca ctgattacct
    24841 atctggttag tataggagtt ttggtttttg gggtaaattt caatctctac tactacctta
    24901 tgctccgtcg ggttaaggcc ttctttggag atgaagagct tcgggcttac ttggtcatcg
    24961 tgctggtttc tacaggcttg attagcctca atactctcta cctctaccca gggttttcaa
    25021 agagctttga aatgaccttc ttccaggttt ccaacatcat tacaacaact ggttttggat
    25081 atggagatat taccaactgg cccctcttct cccagtttat cctccttttc ctcatggcaa
    25141 tcggtggctc tgctggatca actgcaggtg gactcaagat tattcgaggc ctcatccttt
    25201 caaaaattgc caaaaaccaa attttgtcaa tcctatcgcc ccaccgtgtt ttgaccctcc
    25261 atgttaataa aatggtgatt gacaaagata cccagcataa gattctcaag tactttgtca
    25321 tctatgctat gattttgcta gcgcttatct ttattgtcag cctagatagc aatgattttc
    25381 tggtcgtgac cagcgctgtc tttagctgtt tcaataatat cgggcctatt ctaggaacca
    25441 cttctagttt ctcaatcttt agtcccatct caaaaattct cctctccttt gcaatgattg
    25501 cagggcgctt ggagatttac ccaatcctcc ttctctttat gaaaagaact tggtctaaga
    25561 gataaaatac aaaatccctc tttttacaat tgtgaaagag ggatttttat attaaaaagg
    25621 gggaacgttt ttaaatccaa gcctgtctgt aagcaaagtt cttactcaaa taaaagatgg
    25681 aaaaacttac tacacagctt ggtaatgctc caatacaaat tgtaaggctt tacttggatt
    25741 ctttgttaaa tgaatatatt ccattcctct ggtagcaact atctgaatac ctaatctttc
    25801 tgcatccacc ttcatctctc tataataact ccgaacttgt ggagccagaa taattaaatc
    25861 ataaacaccc ataatatcat aatgagctcc gtacgctcct gaattcgcaa tcactctaac
    25921 ttctgctaat tgagcgccct cgttaattgc attggctaat tacgcacttg ttccagaccc
    25981 tgcacaaaga accagtactt tcaactcctt actttttatt acatctatct caccaggcat
    26041 tatttcactt gtatcctcct ctaaaataat atcatttgag cttgcaatat ctacaacctg
    26101 tagtagatat ctcgtattta gacaatatga aaacaagacg acttccatat aggaaaccgc
    26161 cttctctcta tgttgagtga tttatattaa aataactttt cttctagctg cattttatta
    26221 ttataaaaac attcatcata accctgaact taaataacga tttttattca agatacatac
    26281 tcctagaata aactttatat gaaattctca tttttgtttt tacaattctc cttagttaaa
    26341 tcttgtttaa tatatgtttt acatatagta tttagcgcca catagtactg aactctctcc
    26401 aaaaacggtt attcctcttt gaatagggcg ttatcacaag aaaagcatct ccacgtttca
    26461 acttcatatg gctcaaaaac aatcaattga tgctaaaacc tgtacctaga tgtttcggtt
    26521 cataaaacca tgaaactgta aaagtgaatg aaattgatag cgatagtcaa atcaagaggc
    26581 atcataactc taaaaagtca caatatataa gttcatcctc ggaaaaatat cattctaatt
    26641 gttgaaatgc ctacatgaaa agaaacgtca aatgctcatg aaacaacgaa tacaggtatc
    26701 aaaactatga caaaacaagt ccctaaattt actaaagaca ctgctcaact ttacacctgt
    26761 aagtggttgt tgtataataa agttacaaag atgtacgacc acactgttgt aaatcatagt
    26821 gttcgcgaat atattactga tagcatttct acaaatacaa ttgaagagac tggatagact
    26881 ttaaacgaaa tatgtcagtg ttttggcatt cctagccttc atatcattta aagaattcta
    26941 tagacaaaat ttttcccaat acagacactc gtaacaactg cttcattttt ctaccaacat
    27001 atttaggaac aggataagat acaagaggat taatccatag atcagttcta taccaatcta
    27061 agacaaataa gctaaaaaaa cgattgataa taagcaaata gattccaaat tttctctatc
    27121 tgctcatttt aataaacaat actagtgtaa ctatccttcc agtcagaaac ttgtcaaatc
    27181 acaccgaaaa ctcttctaaa atttatctcg ttaggcaatc aagcaaaaac tcgacgatag
    27241 tacaaacatt atcatacaga attgactgcc taaattatat actttagtaa ggttttcgga
    27301 taagaaaaaa ggttcatttt acatttctaa acattctttt ctaagatgaa aaacagaatt
    27361 tttcgattgt gatttaaagc aacaagaaga ttttcagtat catcctatag atacgagcta
    27421 attaagaaaa actacatttt tgaatataaa ctacaataat ataaactaaa ttttatagga
    27481 ggaagacaat ggattggtac gattatatga tacaggcatc caaacaatca caattcaacg
    27541 caagccattg gtttcgctat ttgcgaaaag ttatttttga agactattct tatttaacaa
    27601 accaagatgt agaaaagttg ctagactcca aagaactaac ccgttttcaa aaaattagct
    27661 tgaagtatgc ctttcaagag catactccaa ctcataaata tgtgatttca ttaaataaac
    27721 ctgctaagtt aaccaatgtt caaaaattga tggagaaata caaacatgga taaaatgaaa
    27781 ccggtcttcc aagccctaaa taagaaatta attcaggaaa atctgacttt aacaattatg
    27841 gttatgtctt agaatatcat ggtttacgta ccacacaaga tgttgatgct ttttatgacc
    27901 aaaatcagaa aatcaatgaa attattgctc gtgtaggaaa acagtttaat cttaacatcc
    27961 acgaagagtt atggctcaac aatcatgttg caaagcaaat atgaacaaac aacctccctt
    28021 aagtttatgc gaatccttgt actcatttga gaatctgacc gttttagtag tccctattga
    28081 gtatgtgtta ggaatgaaga tgatgagtat cagagagcag gatttgcaag atattggtgc
    28141 aattattaaa tacaaaaact ttcattcacc attcgatacc tttaaatatt taaaagacat
    28201 gggatttgat actattgacc tctctgttct attagaaggt tttagttatg cttatggtat
    28261 ggattggtta gaaaaatttt ttaaagaaaa tcaagataaa cttcgcgaat tttattaaca
    28321 gtatcaaaca agatgattgt caattagcca gtcatcttat ttttatgatg aaatgaaata
    28381 aaatcggaac aaatcactta gagaattcca gtcaatttct agcactgttt gagccgtttc
    28441 agcggactat agtaaaatga aataagaata ggacaaatcg atcaggacag tcaaatcgat
    28501 ttctaagaat gttttagaag taaaggtgta ctattctagt ttcaatctat tatatttcag
    28561 attcggtcca ctattccttc ccaaaaacat tgcatattgc gccgaaggaa ttgctcatac
    28621 tatcccaagc acaaaaccct cagtcgtttg accgagggtt ccttttcatt attcaaaaac
    28681 ttgattagct caatgcatcc aaggcatcat ccattgaaag aacttcgtgg aagacacgtt
    28741 gtgtcaattc agttttttgt tctggagtga ggtatttagt atttacacag tatccagaga
    28801 tacgtacgat aacgtcttca cctgacataa ttttttcgta aacatcgttc aagtccataa
    28861 cgttcaagtt aacgtgttgt ccaccgtttt cgaagtaacc atcaaggatt gttaccaagt
    28921 tatcaacttg ttcatcacga gtcttaccaa gagcgcgagg tgatacttgt gtagtcaatg
    28981 agataccgtc agctgcataa ctaaagtcaa ggctagaaag tgagttcaag ttttgcaacc
    29041 aaccaccttt agctttgtta gatgggttag cacctggtga gaagaattca agtttagaca
    29101 agttcacaga accatcttcg ttgaggtata cacctttgtg aactggtgag ttaccagttt
    29161 gtttagagta agcaacgtta gatgtgattg tcaaaagtga tactgtagct tctgcgtctt
    29221 tgtatagttt gtggctacgt agacgagttg tgtaagcttc gatcaaccat tctgccaatt
    29281 cgtttgaacg tgggtcatct tcaccccagc gtgggtagtc accgattgtt tcgtaatcgt
    29341 agatgtagcc atcttcgtca cggattggtt taactgtagc gtatttgata gctgacaatg
    29401 tatcaacagt gttagcaaat ccacagatac cgaatcccat gttggcacgt tgtttagttg
    29461 gcaagaaggc catttgaaca gcttcgtagt tgtacctatc agtcatgtag tggatgatgt
    29521 tcaaggcatc tacgtaagtg tcagtcaacc agtcaagaga tttttcaaag ttcgctttaa
    29581 ctgattcgaa ttcaagaact tcgtcacgga ttggttcgat atcaaatact ttgtagtctt
    29641 tgtgaacatc gtcgtaacca ccattcaaac cagtaagaag ggctttaaga acgtttacac
    29701 gagcaccgaa gtactggatg ttgtggcgtt gttcttcatt ttctggatca agtggagaca
    29761 cacagcatga gatacagctc atttcaccat atccgtcttt agccattgtt gttacacctt
    29821 cgtattggat agaagagtgt ttgtggctca tgtgcataca gtagcgacgg aagttgtatg
    29881 gcaatttgtc agtccaaaga actgtcaagt ttggttctgg tgagttaccg atgttgtcaa
    29941 gagtgttcaa gaaacggtag tccatcttag taacacggtg acgaccgtcg ttacccatac
    30001 cagccataga agttgtgata aaggttgggt cacctgagta caattggtca taagcttttg
    30061 tacgagcaaa tttaactgta cgaagtttca taacgaaatc atcaacgaat tcttggattt
    30121 ctgattcagt aaatgtacca cgagcaaggt cacgttctgc aaagatgtcc aatacgattg
    30181 gtacacgacc tagagatgta gcagcaccgt taatcacacg gcagacagcc atgaaagcaa
    30241 tgttaaccca ttggattgct tctttcacgt tcatcgctgg tttgcgaaca tcaaccccgt
    30301 aaaggtcacc caggcgaaca acttgttgca atgcttggta ttgaaggttt acttcttcac
    30361 gaagacggat tgtttcttca tcgatttctt tgattgcatt ccagtcattt actttttctt
    30421 gcatcaagta gtctgcaccg taaagagcaa gacgtgcgta aacaccgatg atacgtccgc
    30481 gtgagtatgc atctggaaga ccagttacag tgtgtgcgtg acgagcgcga cgaatatttg
    30541 aagtgtaggc acggaaaata ccgtcgttaa ctgttgttac atatttagtg aagatttcgt
    30601 gaacagctgg gtctggttcg tatccatttt ctttcaaagt agtttcagcc atacggatac
    30661 caccttttgg catgaagttc aatttgaaga gttcatcgtt ttggataccg aagataactt
    30721 cattttcttt gtcgataaat ccagcaggga tatcagcgat agatgttgga cgagtgtcca
    30781 ttgggaaacg agtttcttcg tagtgtgctt tagtttcttc tacaattttc ttgatgtgaa
    30841 gtgaacgctc tgttggtcct gcaaggaagc tttcgtctcc atcataaggt gtgtagttag
    30901 cttgtacaaa gcgtgataca cttgcttttt ctttccaatc tacgcctttg aagccttccc
    30961 aagctttgtc aaaaatatct tgtgcttcaa caactgtctt aacaaccata ttaatgtcct
    31021 cttttttcta gtaacagtca tctgttacat tcatgagaca agtataccat atagtaaccg
    31081 attttaacaa gtgaaaaatc cctattttta cactttcttt tctaaaacag tctatatttt
    31141 atttcaaact gtattatatt tttgaaaaaa taaagtcctt ttttcttttt ttcagaaaaa
    31201 agggtataat aaaagaaaat aagcagtaac actcaatgga aatcgaaaag caaactagga
    31261 agctagccgc aggctgctca aagcactgct ttgaggttgt aaatagaact gacgaagtca
    31321 gctcaaaata ctgttttgag gttgcagatg gaagctgacg tggtttgaag agattttcga
    31381 aaagtataaa aaggtgctag gcatgttgat ttttcctttg ctaaatgatt tgtcaagaaa
    31441 aatcatccat attgacatgg atgccttttt tgctgcggtg gaaatcaagg ataatcctaa
    31501 actcagagga aaacctgtca ttattggaag cgaccctcgg caaacaggtg gacggggagt
    31561 cgtttctacc tgtagctatg aggctcgagc ttttggtgtc cattctgcca tgagttccaa
    31621 ggaagcttat gaacgttgtc cccaggccgt ctttatctca ggaaattatg agaaatacaa
    31681 agctgtggga ctccagattc gagctatttt taagcgctat acagatttga ttgaacccat
    31741 gagcattgac gaagcctatt tggatgtgac agaaaataaa ctcggtatca agtcagcggt
    31801 caaaattgct cgcctcattc aaaaagatat ctggcaagaa ctccatctaa ctgcttctgc
    31861 cggtatttcc tataacaagt tcttagctaa aatggcgagt gattatcaaa aaccacatgg
    31921 tttgacagtg attctacctg aacaggctga ggattttctc aaacaaatgg atatttccaa
    31981 atttcatgga gtaggaaaaa agacagtaga acgtcttcat caaatgggcg tttttactgg
    32041 tgctgattta cttgaagttc ctgaggtaac cctaatagac cgttttggta gactaggcta
    32101 tgatctgtat cgaaaggctc gtggcattca caactctcca gtcaaatcca atcgcatccg
    32161 taaatcaatc ggcaaggaga aaacctacgg gaagattctc cttgctgagg aagatatcaa
    32221 aaaagagctg actcttctat cagaaaaagt cgctctcaat ctacatcaac aagaaaaagc
    32281 tggaaaaatt gtcattttga aaatccgcta cgaggacttt tcaactctta ccaaacgaaa
    32341 aagtcttgct caaaaaacac aagatgctag tcagataagc caaatagccc tgcaactcta
    32401 tgaagaatta agcaagaaag aaagaggtgt ccgcctattg gggattacca tgactggatt
    32461 ttaaagctca atgaaaatca aagagcaaac taggaggcta gccgcaggct gctcaaaaca
    32521 ctgttttgag gttgcagata aagctgacgc ggtttgaaga gattttcgaa gagtataaaa
    32581 ccttgaagag ttgccccttc aaggtttttc ttatacaaat aaacggacaa aactgtaaag
    32641 tagcaaaaca ctaccaagca cgatacggta tttaccaaaa agggtgaagt cgtgtttttt
    32701 cacatagctg gtcaagaagc gaatagccac catgctgacc gcaaaagcta ctcccatcgc
    32761 gaccaagagc aaaaacaatt gcccaaagct caagagttct ccggctttca caaatttgaa
    32821 aatctttaag gcactagctc caaacataac aggaatccca agatagaagg taaattctgt
    32881 cacaactgaa cgactggttc catttaacaa accaccgaca atcgttgcac ctgaacggct
    32941 agtccctggt aaaagagcaa gaacttggaa gagtccgata tagaaagcgg tcgtataagg
    33001 aagcttgtcc aactctgtta cacttggctc gatagcacgc gctttattgc gcttttccaa
    33061 atagatgaag gcaaccccgt agataatcaa catgagagca actgaaacca tgttatggaa
    33121 gtgggtatca aaccaatcat caaatttaaa gacaccaagt aaaggtaaag tagcaatcaa
    33181 gaccttcaac catagtctcc aagtcttacg aacttcctgt ttgtccttag tcggtttaaa
    33241 aggattgagc ttgttaaaat aaatcaccat aactgctaaa atagcaccaa gctgaatcac
    33301 gacattaaac atggacataa aggcttcatt ttgattttgg tattggatga attcctctgc
    33361 taaaatcaag tgacctgtac tggaaatcgg caaccattcc gtaattcctt caacaatccc
    33421 gaagaagata gattttaaaa tttcaataag atacatagat tactccctat attataatta
    33481 gcgcagttag ctactgccaa agcccaagtg gtatacttgg aataagccac tgtggattag
    33541 ttcatttcct ccaatcgctt gacgatttcc gaaaggatct aaccacagct tttgtttcaa
    33601 ttggtaatga gtttgataac gcatagacgt tttatctcgt ctaaggtaac aaggcaaaaa
    33661 gttcgtggat aaccaagtag acttgaaata ctatatctgg aggtactccc atgctttatg
    33721 tgggcattga tatcgctaaa aataaacacg atgttacagc cttgaatgtt ccaggaaaaa
    33781 ctgttcttaa accactcact ttttcaaata ataaagctgg ttttgaactc ttagatctgt
    33841 ctcttcgaca gctcaaccaa gactgtctca tcgctcttaa acttctttct gatcccaatc
    33901 gtgaacaatt tcaacacgat aatcggcaag tagacctaaa aatactggct agacatattc
    33961 atcgtctcaa gaaaaaacag tctgattgga aagtacaata cactcgttgt cttgatatca
    34021 tctttcctga gttggataaa atcgttggaa agcattcaga atatacctac caactcttga
    34081 cgcgctaccc taatcctcag aaaaggattg aggcaggatt tgataagctg atagaaatta
    34141 agcgattgac cgcttctaaa attcaggata tcctctcagt cgcacctcgt tctatcgaaa
    34201 caacatctcc tgctcgtgaa ttcgaaatca tcgaaatcat caaacattac aagaggctca
    34261 ttgacaaggc ggaaacatgt gtcaatgact tgatggctga gttcaactca gtcatcacga
    34321 cggttactgg gattgggggt cgtttagggg cggtcatttt agccgagatt cgaaatattc
    34381 atgcctttga taatcctgct caattacaag ctttcgctgg actggattct tctatttatc
    34441 agtcaggtca gattgattta gctggaagaa tgatcaaacg gggttcccct catctgcggt
    34501 gggcactcat acaagctgcc aaagtatgcg ctcgcttttc acctgctttt aaggcctatc
    34561 ttaagactaa gttagaacaa ggaaaacatt acaatgtagc catcatccac cttgcaaaaa
    34621 aacttatccg aaccctgttt tatatcctaa aaaagagctg ccatttgacg aacaaaaagt
    34681 gatgtaattt ctgaaattaa cacaggatta cctttgaaaa aatggacttt ttcaatagct
    34741 ttttgccgtg ctctaaaatc atcgccaaat catcaaattg aaataagaaa tagtttagat
    34801 aaaactattg acttttctta tagtttgtct ttcttctatc ttccattata tcatactttt
    34861 tcagtctatg gtagctctct ttaaaaggct ccgatactgc cgccacctcc gcctccagag
    34921 aagccaccgc cagaacttcc acttccagaa gatacggagt aggtacttgc tgtatttgcg
    34981 acactagcat aatggctcat ttgcgcgctt gaatgataaa acatactgtg ccagccataa
    35041 gctacataga gattgatatc tggattttca acttgaatct gatgaacctt catcaaatga
    35101 ctaaccttgt ccgcatagcc aaataaggtt gcatagacca agagacgatt ccaaacaaca
    35161 atactttcca attcagcctt atccagtcgt gcaatctcac gtaacatatt ttcaaaactg
    35221 gtccagagat agtagacctc agctcccgct tcatttagaa caccatcacg attatctagt
    35281 cgaagcttcc aataatagaa aacagacaaa actaacccta gaaaaccaag tattggcaaa
    35341 gggaggtaaa gatagccatg aacgtctaaa ctgtacaaga acaaaccaaa tccgataaat
    35401 aggggcaaga tagtcaagac acccataccc acttgcaaag tcttttccaa accagttaaa
    35461 ggacgatagt aatctgggag cccccagaag gaaactcgtt ttctcactcc ttcttgcatc
    35521 tggttcaata cctcttcaaa agaagatttg agttgaagcc ctcttgcttg aatccgtttt
    35581 tcatcagaaa ctttggctct acgataaaga ctatcagata ccttgtaatc cgcaaaaaaa
    35641 ttggaaagag tggcttcttt tttgcctgaa aaggctagat ttagacagtc tctctcaaat
    35701 cttgacaaac catcttcttt caccaatctc aagccaactg catctccttc tgaaataata
    35761 gagacattcc cacggtctat cacatctagc aaggtagctt gaataagttg gtcaaaagtg
    35821 aatttgccag cccccttgac caagggactc acttcctcca aggaggtcga gtagactgct
    35881 tctgataaaa ccataggctc taattccatt ggtggttcat agagacgatg atttttggca
    35941 tatttgactg aaggagtggt ctttcttcta taaataaaat agaagcagac actcaataac
    36001 aaggagatag aaagtatcga agggaggacc caagtaacga gttgtttact ctgatctttt
    36061 tctctaacaa tcgagtcttc tatcttatta aactcttcta aacgattccc tttcaagccc
    36121 tgatccctag cgctagcaaa atcggtccga gaccaatagg catgcaactc aactccacgc
    36181 ttagccggaa gattgtctaa acggatagta taatcaaggt tactcttttc aatcgttccc
    36241 tctctaaaaa gtttccctgt atggaaaaag agtttctcag cccccttgtc tccccttaca
    36301 tgaaattcaa acttttcaat agactctgaa ctatctgtca gaggttgcca atttaattca
    36361 gcgatatcat cataaaggaa aagtaaattt tttaagttcc agacgaggtc aacttcaact
    36421 atgtcgccct cctgacctgg attatagact ctcacagtat aaccatccgc ttcttctgtt
    36481 acttcgctag tcacatctgc tagttctgca ccgtttttcg cagcctgaac ctttggatga
    36541 gggtcaatgt caaacccgct aggcatctta ccagcacgtc caagtcccac gatttggccc
    36601 ttaaagtcct cctcaaactg gtaaactatc ttctgtctaa actctgccgt attatctgca
    36661 tgaatataca aatccccttg ataagagttt atcttgaaat caatggcaaa aacagagagt
    36721 ggaagaaggc aaaacaagcc taacaccagt aagaaaaaag tttttttcat caactaagcc
    36781 ccctttttat ctttcttatc attatagcat cttttcgtaa gtaaaggctt acttatgttg
    36841 aaaaattacg catttttcga taaaatagga gacagttatt ttttaataga tcagaatagg
    36901 agaaatcatg agaaaaatat acctatctat tttcacaagt ctcttgctga tgctaggact
    36961 tgtcaatgtt gctcaagccg atgaatattt acgcatcggg atggaagcag catatgctcc
    37021 ctttaactgg acccaggatg atgatagcaa cggagctgtc aaaatcgatg ggaccaatca
    37081 gtatgccaac ggatacgatg ttcaaatcgc caagaaaatc gctaaggact taggtaaaga
    37141 acctttggtt gttaaaacca agtgggaagg tctagtccct gcccttactt ctggtaagat
    37201 tgacatgatt atcgcaggta tgagtccaac tgcagaacgc aaacaagaaa ttgccttttc
    37261 gagcagttac tacactagcg aaccagtttt gcttgtcaaa aaagattctg cctacgcaag
    37321 tgctaaatct ttggatgact ttaatggtgc gaaaatcact tctcaacaag gtgtctacct
    37381 ctacgacttg attgcacaaa tcccaggtgc taaaaaagaa acagccatgg gagacttcgc
    37441 tcaaatgcgc caagctcttg aggctggtgt cattgatgct tatgtttctg aacgtccaga
    37501 agcactgact gctgaagctg cgaactctaa gttcaagatg attcaagtag aacctggttt
    37561 caaaactggg gaagaagata cagctatcgc tatcgggctt cgtaaaaatg acaatcgtat
    37621 tagccaaatc aatgccagca ttgaaaccat ttcaaaagat gaccaagttg ccttgatgga
    37681 tcgtatgatc aaggaacaac ctgccgaagc tacaacaact gaagagacta gcagtagttt
    37741 ctttagccaa gtcgctaaaa ttctttctga aaactggcaa caactcttgc gtggtgctgg
    37801 tatcactctt ttaatctcta tcgtcggaac catcataggt ctcattattg gacttgccat
    37861 tggtgtcttc cgtactgctc ctctctctga aaacaaagcc atttatggcc ttcaaaaact
    37921 agtcggctgg gttctcaatg tctacattga aattttccgt ggtacgccaa tgattgttca
    37981 atcgatggtt atctactatg gaactgccca agctttcggg atcaaccttg accgtacact
    38041 ggctgctatc ttcatcgttt caatcaatac cggtgcctac atgactgaaa tcgtccgtgg
    38101 tggtatccta gcagttgaca agggacaatt tgaagctgcg actgctcttg gtatgaccca
    38161 taaccagacc atgcgtaaga ttgtcctacc tcaggtagtc cgtaacatcc tacctgcaac
    38221 tggtaatgaa tttgtcatca atatcaaaga tacatctgta ttgaacgtta tctctgttgt
    38281 cgaactttat ttctcaggaa ataccgtggc aacacaaacc tatcaatact tccagacatt
    38341 tacaatcatc gccgtgattt actttgtcct caccttcacc gtaacacgta tcctacgatt
    38401 tatcgagcgc cgaatggaca tggataccta tactacaggt gctaaccaaa tgcaaacgga
    38461 ggatttgaaa taatgacaca agcaatcctt gaaattaaac acctcaaaaa atcctatgga
    38521 caaaacgaag tgctaaaaga catttcactc actgtccaca agggagaggt catctctatc
    38581 atcggaagct ctggaagcgg aaaatcgacc ttcctacgct ccattaacct acttgaaaca
    38641 ccaactgatg gacaaatcct ttatcatgga caaaacgtcc tcgaaaaagg ctatgacctc
    38701 acgcaatacc gtgaaaagtt ggggatggtt ttccaatcct ttaacctctt tgaaaatctc
    38761 aatgttcttg aaaacacaat cgtcgctcag acaactgtcc taaaacgcga acgcacagaa
    38821 gctgaaaaga ttgccaaaga aaacctggaa aaggtcggca tgggagaacg ctactggcaa
    38881 gccaaaccaa aacaactctc aggtggtcaa aaacaacgtg tggccatcgc tcgtgccctc
    38941 tccatgaatc cggacgctat tctctttgat gaaccaacat cagctctcga tccagaaatg
    39001 gttggagaag tcctcaaaat catgcaggac ctggctcagg aaggcttgac catgattgtc
    39061 gtaacccatg aaatggaatt tgcccgtgat gtctctcacc gtgttatctt tatggataag
    39121 ggcgtgatcg ctgaagaagg taaaccagaa gacctcttca ccaatcctaa agaagaccga
    39181 acaaaagagt tccttcaacg ctatctcaaa taaaaagaaa aggctgcatc aaccgtgcag
    39241 tctttttgct gtcctcaaaa tgaaaaggca gattctctat ctctactact tgaaggtcaa
    39301 gaatccgccg ttatccaaag attaatcttc aaatttttca taattttttt catagaaatc
    39361 aattaagcct agggctgttt caaatgaaat attttttact tttgcacgac cctgcgccag
    39421 agcaatgata gacatttcac gcgcattcgt ttctttagag atacggtagc ctgtgatttt
    39481 cttatcacga acccagccaa caactgattc tactttttca aagtttgact tagccatgtt
    39541 tttctcctat tttcttcttt ataatattta attgtatacg tttttactac ttttgtcaat
    39601 aaaaaaaaca tatattcaac gaaaataatt agttcagaat tttcttactt cctttttaaa
    39661 tccgataata tataggtttt gctagcctct acaccataaa tatttgctaa taaaactact
    39721 gtattattac cctcttaagg tgcgaaatta ttcaagttct taaaaaatgc ttctctattt
    39781 ccgtaagata gcttatttct tcgatttaag aactgaagat gatagttcta acctttagaa
    39841 atccaagcct tcactagctc aaaaactcct atctttcttc ctcaataaat catctgagag
    39901 ataggtattt cttatatcct tcaaattcat cactcctttg gatattgagg tgctagccta
    39961 gaagcagaca cccgattatc taaaccatcc ttaatagaga tgacaagaca gataagctca
    40021 gttaattact tatatatctt tttaatatgg tatatttgtc aacaaaaaga aatcaaatca
    40081 taccttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcaa gttgctcaaa
    40141 acactgtttt gaggttgcag atagagctaa cgtggtttga agagattttc gaagagtatt
    40201 aaagacagtg tgactatgct tgtcaataga taggaaatca aaatgaagga tggaaatctg
    40261 agccaaacat cataagtgct ataatgaaca gaagtaagaa ttgcacgata agttttctaa
    40321 aaccatagga atcgtcccct ttcttcatct tcattatagc atatatacat cagttgtaca
    40381 aataatatga tattttttta ttagtcctca gacaagcata ttataaagcg tttcattacc
    40441 atttaagtta atataagctg gatcaaaacc ttccattcta cgaatcaaac ctgcataatc
    40501 atgcttatct gctaaagcga tcccaatcaa tactgggcct gttcccttgc tagctcgttt
    40561 gatatactca aaacgtgtga tatcatcatt tggccccagg atatcattta caaactcacg
    40621 caaagctcct ggacgttgtg ggaaattgac cacaaaataa tgtttgatac catcataaat
    40681 caaggcacgc tcttccattt ctggcatacg gttgatatca ttatttcctc cagaaatgat
    40741 acaacaaatg gttttcccct taatatattc agctaaaacc tctaaagagg cgatactagc
    40801 tgctccagca ggttctgcga ctatcccttg cttagagtaa aggtcaatca aggtttcaga
    40861 aatcaatccc tcatcgacac ctaccaaagt ttgaatatgt tgacgagttg cttcataggt
    40921 caactgacct accttttgca cagcaatccc atccgcaaat ttatcaattt ccttgagttt
    40981 gactggacct ccagcctcaa aggcagcttt catggaacgc gctccattcg cctctactcc
    41041 gataacctca atctctggac ttgtttcctt gatataggta gaaaccccgg caatgagacc
    41101 gccaccacca acaggaacca agacagcatc aaaatcaatc gattcttttc gagcttcttc
    41161 taaaatctca taagcaactg ttccttgacc tgcttgaaca tgagcatcat caaaaggatc
    41221 aataaaggta cgattttcag agactgtaaa ttcttgagct gctttggctg aggcatcaaa
    41281 ggtatctcca actagtttaa tagttacaaa atccccacca aaaaagcgaa cctgaccaat
    41341 cttttgttgt ggcgtagtaa tgggcataaa gatagtagca ggaattttca tttcattaca
    41401 agtataggct actccctgcg catgatttcc cgcagaagcg caaactaccc cacgttcacg
    41461 ttcttccttg ctgagctggg aaatggcata ataggcacca cgaattttaa aggagcgaac
    41521 acgctgggca ttttcttttt tcaaataaat cttagcacca tacttctccg ataaataatg
    41581 atcgtaatcc agtggagtat tcacaaccac accgttcaag accttgtgag ccttgattat
    41641 atcttttgaa cttaacatat aaaacctctt tttctataaa aaacagtcac taatgactgt
    41701 tttttagtta ttcatctccg aaaatttcag taacactttc atggtattta tgagccatac
    41761 gaatcgaaaa ctctttagga agttcataac gatttgtgga aatccaatca tataaccatt
    41821 ctaccaaact ttcttcacta tcattacgat ggaagataaa atagtttaaa atttctttat
    41881 attctacatc attcaaatcc aacgtgtcta caaattgact acgaggaaca aaattagaat
    41941 ctaattttct tagttgatct gtcaattctc ccaattgtaa atccaactga aaaaatagtt
    42001 tttgcagttg cctatcagtt tcatcacatc ctgtcttgat agaaaacaaa ttggtaatat
    42061 tcatatgatt tcaaccccta aataagtaca tctaatatcc cacgaatagc tgaagctaaa
    42121 gttttcgcag tccagtcatt taaacccgat tctttcaatc cagatgcaat aatttgctct
    42181 atttgatata aaccgccatc tatcgtctca tttattctgc gaagaggacc ttcaatatag
    42241 gataaagctt ctccgaatct aacagctgat ttaggtccta atgatttacc aactatattt
    42301 gttaatattt tttatttctc aaaatccatt tcgctatata acgagcagat ttagtcgcac
    42361 cagctctctc aaacggagaa tgaatttcaa gaccttcttc tctagctatt tgtgccaatt
    42421 tgaagaattg ttcaaaggtc atatgcaacc taccatcttc aaaattagca tcatcataaa
    42481 tgttaattac agcattttca tcatacgacc aatctgcttt attttggtct gctagcacta
    42541 ttaccgacgg tgtaattaca ttatacaact agaaccaata ataacgatgc aatttttctc
    42601 ataatctttt tcataaaatc atctccagcg ctatatattt ctaattagtt atagattttg
    42661 aatgcatcat cgtcgttttt accaacgaat ggcattgctt tacgcaattc tgcaccaact
    42721 ttttcaattt caaggttagc tgcttgttca cggtaagcag tcaattttgg acgtccagct
    42781 ttatagtcat ttacaaagtc atttgcaaat ttaccatttt ggatgtctgc caagacagcc
    42841 ttcatatttt ctttaacttg ttcagtgatt acacgtggac ctgatacata gtcaccgtat
    42901 tcagcagtgt ttgaaataga ttgacgcatt ttcttgaatc caccttcgta gatcaagtca
    42961 acgatcaatt tcatttcgtg aagaacttca aagtaagcca attctggagc gtaacctgct
    43021 tctgtcaaga cttcgaaacc tgcttcgata agggcagtca aaccaccaca aagtacagct
    43081 tgttcaccaa acaaatcttc ttcagtttct tctttgtaag ttgtttcaag aagacctaca
    43141 cgagccgctc caacaccttt acaccagtcc atagcaatgt ttttagcatt tcctgttgca
    43201 tcttggtata ctgcataaag agctggaaca ccaaatcctt cttcgtaagt acgacgtacc
    43261 aagtgtcctg gtcctttagg agcacacatg aagacatcta catccgcagg aactttgata
    43321 aattcaaagt ggatgttgaa accatgggca aatccaactg cgtttccagc ttccaagttt
    43381 ggagcgattt ctgcttcgta caattcttgt tgaatttcgt ctggcgccaa gatcatgata
    43441 acatcagcca acttagtagc ttctgctact gtgtaagtat caaatccatc ttcttttgct
    43501 ttatcaaaag atttacctgg acgtacaccg ataataacgt cacgacctga atcacgcaag
    43561 ttttgagcat gcgcatgccc ttgtgaacca taaccgataa cggcgatttt tttaccgtca
    43621 agtgctgcta ctttaacatc tttttcatat tccatttgaa ctgtcatagc ttttctctct
    43681 tttctattat ttattgcctt ttaagctggt ttaacaaatt taagttggat ttttaatcgc
    43741 gggtaaatcc agttgcaccc gttcgagcaa tattgcgaat accgtatggg cgaatgactc
    43801 gcaatagggc ttcgctcttt tctgcatttc ccgtcatctg aatggtaatc gagcttggcg
    43861 ctacgtctac cactgttgca cggaaaggtt gaataatcgc taaaatctca gctctcttct
    43921 cagctggcgc tgacatctta accaaaatca cctcgcgctc caaatgaggc ttgtctgtaa
    43981 tatctcgaat gcgaatcaca tcaatctgac gattgagctg tttgatgatt tgctccactt
    44041 catcatgaga agcaacatca ataataatag tgatacgcga tacattcgga tcttctgttg
    44101 ctccaacaga gatgctttca atattaacct gacgacgaga taggacacct gtaaagcgat
    44161 tgaggactcc tgaacgattt tgtagttttg ctgttaacat tctacgcatg gaactgcacc
    44221 cccaacatct catgattact cttaccagcc ggtaccattg gtaacacctg ttccttacga
    44281 gaaatatcta cctcaattag cataggaaca tcctcagtga tgacttcaag gtcttgagcc
    44341 aaggtctcag gattgtcaaa cttatagttt ttaataccat aagcctgcgc catcaattgg
    44401 aaatcaggaa gggtatcaaa gaccgactct gatgttctgc cttcatagaa ggattcctgc
    44461 cactggcgaa ccattccgag tgaatgattg ttcagcataa ccaccttgat tggcaccttg
    44521 taaatattca aaatagccaa ctcctggttg gtcatttgga aaccaccatc cccaacaaac
    44581 aagactactt ccttatctgg gttagcaatt ttagcaccga ttgctgctgg aattccaaag
    44641 cccattgttc ccaaaccacc tgaagtcact aactgacgtt cattttggta gggataatac
    44701 tgagctgtcc acatttggtg ttgaccaacg tctgttacca caatggcatc tccattcgtc
    44761 aattcaccaa ttcgttcaat aactgcttgc ggttgaacca cacgctcttt cttgtcatac
    44821 gaacgaacac gattcttgtc tttagtgact ttctcaatcc acttttcagt attgttgtga
    44881 actgttggtt ctgctagcaa catttgcaag gccttcttag catctccaac tacaggaatg
    44941 tctgcactga taatcttgcc aatctcagct gggtcaatat caatgtgggc aaccttagca
    45001 ttcttagcga aagtcttagg attccccgtc aaacggtcat cgaaacgaga accaatacta
    45061 atcataaagt ccgcttccgt catggcaata tttgctgcga atgacccgtg catgcctccc
    45121 attccaagaa agagtgggtg actcgttgca atcgttcctt gtcccaaaag actggttacc
    45181 actggaattt gatagcgttc tgcaaattca tttagttccg tagcagcctc agcataacta
    45241 attccaccac cagctaacaa gactggcttt ttagccttgg acaattgctt caagattttc
    45301 ttgatttgca tatcattcgg ctcaagagtc ggctgataac ttggtaaatt cacttctggt
    45361 gaataaatga agtctgtttc taaagcagat atgtcttttg gtaggtcaat tacaactggc
    45421 cctggacggc ctgtagttgc gatatggaca gcttccgtaa tgatacgcgg aatatcagct
    45481 gtctcacgaa cttggtaatt gtacttagtg attggcatgg taattcctac gatgtctgcc
    45541 tcctgaaagg catccttccc aatccctgct cgcgccacct gacctgtaaa gaccaaaagg
    45601 ggaacgctat cgctcatagc atccgcaatc cctgtaatgg catttgttgc tcctggtcca
    45661 ctagtgacga cggcaacacc caactttcca gttgatttgg catagccttc agcttcatgc
    45721 aaacaacctt gctcatggcg ccctagaatg tggcgaatgc ctttaaaatt atatatcgca
    45781 tcataaaaag gcaaaaccgc accaccagga taaccaaaga tggtatcaac tcctaaatca
    45841 cgaagtgttt ccaaaactag gtccgacccc gtcttaggag attctaaact gattttctcc
    45901 attattcccc tttctttcct cttaaaaata acttgttact atcataccat tttttcaaaa
    45961 tttttcaaga taaaagaaga aattttctga attttctatt ttaacgttta tttatgaatg
    46021 ttatttttgt ttttattaaa aagataccga tttcatttac taaaaagaaa aaagaactga
    46081 tttctcagtc cttcattaat cttattccac actaaatagg tatgggtaaa caggttgttg
    46141 accttggtga atctcgactt caacgtcttc gaattcttct acgatttctt gagcgatttc
    46201 attggcaagt tcttcgcttc cgtcttcacc gacatagaag gttacgattt cactgtcttc
    46261 atccaacata tgtttcaagg tttcagtcaa tgtttggtgc atatcagggt ttgacacaag
    46321 aatttttcca tccaccatac ctaaattatc gttttcatgg atttctaagc catcgatcgt
    46381 tgtatcacgc acggctgttg tgacgcttcc gctaacgaca tcgctaagag cagctgtcat
    46441 acgctcttgg ttttcttcaa tggacttgct tggatcaaag gcaagaagac ttgtcatacc
    46501 ttgaggaaga gtgcgagcct ctaccactac cgctggttgc tccaaaactt ctgccgcaga
    46561 ttgagctgcc atgaagatgt tcttgttgtt tggcaagaag atgatgttac gggcattaac
    46621 ctgttcaaca gccttgataa agtcttctgt tgaagggttc atggtttgac cgccttcgat
    46681 aacataatcc acgccttgag aacagaagat atctgctaga cctttaccag ccaccacagc
    46741 aatcaaagca tactcttttt cttcagccga cttgataact tgagtagctt ctttctcaac
    46801 ctgtgcttcg tgttggttac gcatattgtc aacttttacc ttgaccaagc taccatattt
    46861 gagaccttct tgcataacaa gtcctggatc ttctgtatga acatggactt tgacaatttc
    46921 atcatcgtta acaacgagga gagaatctcc aagctcatcc aagtagttac ggaattcatc
    46981 gtagtcaaaa tctttagcat aggttggacc ttgcttaaga gctaccatga tttcagtaca
    47041 gtaaccaaac gtgatgtcct cagtcgctac gtgaccagct acagacttat gatgctctac
    47101 attgatcatc tcactcatgt tggcaggagt cgctacaaag tcctcagatg caatatattc
    47161 gccagtaagg gctgaaagga aaccttcgta gatgaagacc aatccttgac cacctgagtc
    47221 cacaacgcca acttctttca atactggaag catgtctggt gttttagcta gagctgtttt
    47281 agcaccttcc aaggctgcgc gcatgacttc aacagtgtca tctgtttgct cagctttttt
    47341 cttagcaccg atagcagctc cacgagaaac tgtcaaaatc gttccttcaa caggtttcat
    47401 cactgcctta taggcaactt ccacacctga ttggaaggcc agagccaagt cttgacctgt
    47461 taactcgtct ttatccttga tagcttggga aaatccacgg aaaagctgag acgtaatcac
    47521 tcctgagttc ccacgcgcac ccatcaaaag ccctttggca agaatgctcg ctacttctcc
    47581 aactgtagaa gctggcttgt ctgcaacttc tttagcacca ttttcaatgg tcattcccat
    47641 atttgtccca gtatctccat ctggaactgg aaagacgttt aatgaattga catattcagc
    47701 ttgcttattc aagcgagttg atgcagcctg caccatttct tgaaataagc tagtagtaat
    47761 ttttgacacg gttattctcc tacaactttg atattttgaa tgtagacatt tacagtctga
    47821 gcagtaattc caagctggtt ttccaagcta aaggcaacac gctcttgaat gttttttgac
    47881 acttcactaa tctttgttcc gtagcttaac acggtatata catcaactgc aatactgcca
    47941 tcttcggctg cctttacgac gacaccttta gaataatttt ccttacctag cagggcttgg
    48001 aaattatctt tgagggcatt tttactagcc ataccgacca caccaaaaat ctcagttgct
    48061 gctccaccta cgacggttgc aatcacttca tctgttagtt cgatttgacc atcttttgta
    48121 ttaattttta cagtcatcct ttttacctca actagttgat actctatttt atcatatttc
    48181 agcccaagtg taaaagcaga atgatgtatc agcggatatt tactctattt ttcaaacgat
    48241 gttataccca caataaaaga aaaaagaccc taaggtctcc tttgctttta ttattaaacg
    48301 cgttcaactt tacctgattt caaagcacga gctgaagccc aaactttttt aggtttacca
    48361 tcgataagaa cagtaacttt ttgaaggttt ggttttacgg cacgttttgt ttggttcatc
    48421 gcgtgtgaac ggttgtttcc tgatacagtc ttacgacctg taaagtaaca tactttagcc
    48481 attgtgtttt cctcctatta gatctaatat agcggatgtg ctagcaccac ataccgtact
    48541 atgttatcac actttcttgt tttttgcaag ggaattggaa gattttttat ttgtgtctta
    48601 aatcaggtct tgcgtgacat tttctgctct ccacatgcca ttgttgatta acagaacacc
    48661 agaattaaaa ttatgtgtat aaaaatcatc tctaactgca gctaagggta tagccgtcaa
    48721 gtccaaatcc cacagctcat ctatcgattt tcttacaaca atatctgaat ccaaatacag
    48781 tacacgagac tcgcttacat actttggaat aaaataccta aaaaaagccg catatgaaag
    48841 tccctcaaag gggagacgat aacctttcag aatactactg tcaatctgaa cattcacaat
    48901 ctcactattc aaagtctcta gtcttttttc catcaattgg aaccattctc gcggaaggtc
    48961 atcattaaaa acataaaact taagattata atgatgaaca caaagagatt ttattgttgt
    49021 ttcaacttta tccatataag cattatctgc acctaagaca atcgcttttt tctcttcttt
    49081 cactctttat cttatttctt tttattccca tcatattatt cccatcatat gtttctacgt
    49141 aaccattatt ttcgcctatt cgttcgtaaa accataccag tggagatttt agatgaagtc
    49201 ccattacggt ttacaatttt tacattacga cacggagttt tacaaatcga tttcatttgc
    49261 caaacgtagt tagtgaggca gttagctagt tcgccaaata gcgactagcg tccaacaatt
    49321 tggaacttta gctccaattg ttggtactga gtcacatctt ctcctctaac tctacgtctg
    49381 gatacttgtc cgcaaaccag cggagggcaa agtcattttc aaagagaaag actggttggt
    49441 caaaacggtc tttggctaag atattgcgac ttgacgacat ccgttcatcc aagtcctcag
    49501 gcttgatcca acgaacggtc tttttaccca ttgggctcat gaccacttcc gcattgtatt
    49561 cgccttccat acggtgttta aagacttcaa actggagttg accaacagct cccagcatgt
    49621 actcacctgt ttggtaattc ttataaagct gaacggctcc ttcttgcacc aattgctcaa
    49681 tccccttgtg gaaggatttt tgcttcataa cattcttggc agaaactttc atgaaaattt
    49741 caggagtaaa ggttggcagt ggttcaaatt caaacttgtt ttttccaacc gtcaaggtat
    49801 ccccaacctg ataagtaccg gtatcgtaaa ccccgataat atcacctgcc acggcattga
    49861 tcacattctc acgactttcc gccataaact gggtaacatt agatagttta gcccccttac
    49921 cagtacgagg gagattgaca ctcatgccgc gctcaaattc gcctgatacg atacggacaa
    49981 aggcaatacg gtcacggtga cgaggatcca tgttggcttg gattttaaag acaaagcctg
    50041 agaaatcctt gtcataagga tccacaattt caccgtctgt tttcttgtga ccatgtggtt
    50101 ctggagcaaa cttgaggaag atttcaagga aggtctgcac accaaagttt gtcagggctg
    50161 aaccgaaaaa gacaggcgtc aattctccag ccagaatagc ttcctctgaa aactcattcc
    50221 cagcttcatt taaaagctca atgtcatcct tgacttgctc gtagaaagga ttgctaccaa
    50281 agagtttgtc cccgtcttct agactggcaa aacgctcatc ccctttgtaa agctctaaac
    50341 gttggttata gaggtcatac aagccctcaa aggctttccc catcccgata ggccagttca
    50401 tagggtagct agcaatgccc aagatttctt ccaattcttg caagagatcc aaaggctcac
    50461 gaccgtcacg gtccagcttg ttcataaagg taaaaactgg aatgccacga tgtttcacaa
    50521 cctcaaacaa tttcttggtt tgagcctcga tccccttggc agagtccacg accatgaccg
    50581 cagcatccac cgccatcaag gtacgatagg tatcttctga gaagtcctcg tgccctggcg
    50641 tgtctaagat attcacgcgc ttgccgtcgt agtcaaattg cataacagat gaagtaacag
    50701 aaatcccacg ttgcttctcg atatccatcc agtcagattt agcaaaagtc cctgttttct
    50761 tcccttttac cgtaccagcc tcacgaatct cacccccaaa gtagagtaac tgctcagtga
    50821 tggttgtttt ccccgcgtcc gggtgggaga taatggcaaa ggtacgacgt ttcttaattt
    50881 cttcttgaat attcataagt tctctttctt tgattctcta tttttcttgt ttcaatagct
    50941 gagaatgatt tttacattgg attttaccat tcctttcaat actccattat atcggatttt
    51001 agcatttttt tcaatttcta tctcttttca cttccccctc ccttatttat aggaaaatat
    51061 ggtaaaatag aacagactaa aaatcatcat ttcacgaaag gatgcaagat gaaaattacg
    51121 caagaagagg taacacacgt tgccaatctt tcaaaattaa gattctctga agaagaaact
    51181 gctgcctttg cgaccacctt gtctaagatt gttgacatgg ttgaattgct gggcgaagtt
    51241 gacacaactg gtgtcgcacc tactacgact atggctgacc gcaagactgt actccgccct
    51301 gatgtggccg aagaaggaac agaccgtgat cgcttgttta aaaacgtacc tgaacaagac
    51361 aactactata tcaaggtgcc agctatccta gacgatggag gagatgcctg atgactttta
    51421 acaataaaac tattgaagag ttgcacaatc tccttgtctc taaggaaatt tctgcaacag
    51481 aattgaccca agcaacactt gaaaatatca agtctcgtga ggaagccctc aattcatttg
    51541 tcaccatcgc tgaggagcaa gctcttgttc aagctaaagc cattgatgaa gctggaattg
    51601 atgctgacaa tgtcctttca ggaattccac ttgctgttaa ggataacatc tctacagacg
    51661 gtattctcac aactgctgcc tcaaaaatgc tctacaacta tgagccaatc tttgatgcga
    51721 cagctgttgc caatgcaaaa accaagggca tgattgtcgt tggaaagacc aacatggacg
    51781 aatttgctat gggtggttca ggtgaaactt cacactacgg agcaactaaa aacgcttgga
    51841 accacagcaa ggttcctggt gggtcatcaa gtggttctgc cgcagctgta gcctcaggac
    51901 aagttcgctt gtcacttggt tctgatactg gtggttccat ccgccaacct gctgccttca
    51961 acggaatcgt tggtctcaaa ccaacctacg gaacagtttc acgtttcggt ctcattgcct
    52021 ttggtagctc attagaccag attggacctt ttgctcctac tgttaaggaa aatgccctct
    52081 tgctcaacgc tattgccagc gaagatgcta aagactctac ttctgctcct gtccgcatcg
    52141 ccgactttac ttcaaaaatc ggccaagaca tcaagggtat gaaaatcgct ttgcctaagg
    52201 aatacctagg cgaaggaatt gatccagagg ttaaggaaac aatcttaaac gcggccaaac
    52261 actttgaaaa attgggtgct atcgtcgaag aagtcagcct tcctcactct aaatacggtg
    52321 ttgccgttta ttacatcatc gcttcatcag aagcttcatc aaacttgcaa cgcttcgacg
    52381 gtatccgtta cggctatcgc gcagaagatg caaccaacct tgatgaaatc tatgtaaaca
    52441 gccgaagcca aggttttggt gaagaggtaa aacgtcgtat catgctgggt actttcagtc
    52501 tttcatcagg ttactatgat gcctactaca aaaaggctgg tcaagtccgt accctcatca
    52561 ttcaagattt cgaaaaagtc ttcgcggatt acgatttgat tttgggtcca actgctccaa
    52621 gtgttgccta tgacttggat tctctcaacc atgacccagt tgccatgtac ttagccgacc
    52681 tattgaccat acctgtaaac ttggcaggac tgcctggaat ttcgattcct gctggattct
    52741 ctcaaggtct acctgtcgga ctccaattga ttggtcccaa gtactctgag gaaaccattt
    52801 accaagctgc tgctgctttt gaagcaacaa cagactacca caaacaacaa cccgtgattt
    52861 ttggaggtga caactaatga actttgaaac agtcatcgga cttgaagtcc acgtagagct
    52921 caacaccaat tcaaaaatct tctcacctac ttctgcccac tttggaaatg accaaaatgc
    52981 caacactaac gtgattgact ggtctttccc aggagttcta ccagttctca ataaaggggt
    53041 tgttgatgcc ggtatcaagg ctgctcttgc cctcaacatg gacatccaca aaaagatgca
    53101 ctttgaccgc aagaactact tctatcctga taaccccaaa gcctaccaaa tttctcagtt
    53161 tgatgaacca atcggatata atggctggat tgaagtcaaa ctagaagacg gtacgaccaa
    53221 gaaaatcggt atcgaacgtg cccacctaga ggaagacgct ggtaaaaaca cccatggtac
    53281 agatggctac tcttatgttg acctcaaccg ccaaggggtt cccttgattg agattgtatc
    53341 tgaggcagat atgcgttctc ctgaagaagc ctatgcttat ctgacagccc tcaaggaagt
    53401 tatccagtac gctggcattt ctgacgttaa gatggaggaa ggttcgatgc gtgtggatgc
    53461 caacatctcc cttcgtcctt atggtcaaga gaaattcggt accaagactg aattgaagaa
    53521 cctcaactcc ttctcaaacg ttcgtaaagg tcttgaatac gaagtccaac gccaggctga
    53581 aattcttcgc tcaggtggtc aaatccgcca agaaacacgc cgttacgatg aagcgaataa
    53641 agcaaccatc ctcatgcgtg tcaaggaagg ggctgctgac taccgctact tcccagaacc
    53701 agacctaccc ctctttgaaa tttctgacga gtggattgag gaaatgcgga ctgagttgcc
    53761 agagtttcca aaagaacgtc gtgcgcgtta tgtatctgac cttggtttat cagactacga
    53821 tgctagtcag ttgactgcta ataaagtcac ttctgacttc tttgaaaaag ctgttgccct
    53881 aggtggtgat gccaaacaag tctctaactg gctccaaggg gaagtcgctc agttcttgaa
    53941 tgctgaaggt aaaacactgg aacaaatcga attgacacca gaaaacttgg ttgaaatgat
    54001 tgccatcatc gaagacggta ctatttcatc taagattgcc aagaaagtct ttgtccatct
    54061 agctaaaaat ggcggtggcg cgcgtgaata cgtggaaaaa gcaggtatgg ttcaaatttc
    54121 agatccagct atcttgatcc caatcatcca ccaagtcttt gccgataacg aagctgctgt
    54181 tgccgacttc aagtcaggca aacgtaacgc cgacaaagcc tttacaggat tccttatgaa
    54241 ggcaaccaaa ggccaagcca acccacaagt tgcccttaaa ctacttgcac aggaattggc
    54301 gaagttgaaa gaaaactaga cagaacaaaa ccagccctaa ggttggtttt ttcttctcta
    54361 ccaactccca ataactattt tggctttatt tccagagtat tttatggtaa aatgaagagt
    54421 aataatattt attaaagagg taaaaacatg attgaagcaa gtaaattaaa agctggtatg
    54481 acctttgaaa cagctgacgg caaattgatt cgcgttttgg aagctagtca ccacaaacca
    54541 ggtaaaggaa acacgatcat gcgtatgaaa ttgcgtgatg tccgtactgg ttctacattt
    54601 gacacaagct accgtccaga ggaaaaattt gaacaagcta ttatcgagac tgtcccagct
    54661 caatacttgt acaaaatgga tgacacagca tacttcatga atacagaaac ttatgaccaa
    54721 tacgaaatcc ctgtagtcaa tgttgaaaac gaattgcttt acatccttga aaactctgat
    54781 gtgaaaatcc aattctacgg aactgaagtg atcggtgtca ccgttcctac tactgttgag
    54841 ttgacagttg ctgaaactca accatctatc aaaggtgcta ctgttacagg ttctggtaaa
    54901 ccagcaacga tggaaactgg acttgtcgta aacgttccag acttcatcga agcaggacaa
    54961 aaactcgtta tcaacactgc agaaggaact tacgtttctc gtgcctaatc tctagaaaga
    55021 ggtcattcta tgggaattga agaacaactt ggcgaaatcg ttatcgcccc acgtgtactt
    55081 gaaaaaatca ttgctatcgc tactgcaaag gtagagggtg ttcactcttt ttcaaacaga
    55141 tcagtgtctg ataccctttc aaaactttca ctcggccgtg gcatttatct taaaaacgtg
    55201 gacgaagaac tcacagcaga tatctatctc taccttgagt acggagtaaa agttcctaag
    55261 gtagcggttg ctatccagaa agctgtcaaa gatgccgtcc gtaatatggc tgatgtagaa
    55321 ctcgctgcta tcaatattca cgttgcaggt atcgtcccag ataaaacacc aaaaccagaa
    55381 ttgaaagatc tatttgacga ggacttcctc aatgactagt ccactattag aatctagacg
    55441 ccaactccgt aaatgcgctt ttcaagctct catgagcctt gagttcggta cggatgtcga
    55501 aactgcttgt cgtttcgcct atactcatga tcgtgaagat acggctgtac aacttccagc
    55561 ctttttgata gacctcgttt ctggtgttca agctaaaaag gaagaactag ataagcaaat
    55621 cactcagcat ttaaaagcag gttggaccat tgaacgctta acgctcgtgg agagaaacct
    55681 ccttcgcttg ggagtctttg aaatcacttc atttgacact cctcagctgg ttgctgttaa
    55741 tgaagctatc gagcttgcaa aggacttctc cgatcaaaaa tctgcccgtt ttatcaatgg
    55801 actgctcagc cagtttgtaa cagaagaaca ataaaaagaa aaagtgtttg atatctatca
    55861 aacacttttt ctttgcctcc cactatctaa aaaaatgata atagatataa ttgtaaacaa
    55921 aaatccagat aggttttgca tgattgagaa agttaaaaaa actatggcag agaatcgtta
    55981 atctcagatt gtcggtagaa cgataaacaa gggcaaaaaa gaaaccaatc agactataat
    56041 ataataaact aattggatct ctgtgagata gtatcaaatg actaagccca aagataaggc
    56101 ctgataagat gacatctaaa taatacttgg actagggaaa gaaggtattc ataaaatacc
    56161 ctctatcaag agtctcctca aaaacaggac cgatgattac aggcaggaca aaagataaga
    56221 tagtcgataa aaaggttggt tgtccatttg aaagaaccac ggtaaaatac tcatcatgaa
    56281 tattcctatg attaatcaaa tgagcatagc gtgcccaaaa attaccgaga atctgataaa
    56341 ccacataagt tgcaaataag gagaagacaa atgaccagtt ccagctcttt ttctttttta
    56401 acctccaaat taatagaaaa ggaaacttcc cactaatccc actgttaaaa taagagaata
    56461 gacatcagct cctaacccta aaatgatcgt cacatacaat ccaattgttt gtggtaaata
    56521 ggtagatagt aaaataataa gcaaaaatat tccaaattgt cttagtttct ttgtgtttct
    56581 catcgtactt ttttgaaaga ttaccctgtt cggaagccgt acttccaagc atctatataa
    56641 gaattaagtg ccccttgcct catataggga gcaaattctc tataatataa ccatctacta
    56701 tatccatctt cccaaacagc aagaccacct gaagtttgct ccaagtcctc agttgaaata
    56761 actgtaaatg tttctgtacc tgtcattgca agtaccttct taaaatagat tgttgtaggc
    56821 tcacatttat agtatatttc tttttttgtc tattttatag tctatctcct caactggcaa
    56881 tttttcgacc tgaattgcat ttttccataa aaaatgagac ctttctagtc tcatttagtc
    56941 attcttagta ttttctaaat cgttgatagc gttcttccag caactcttct agcggttttt
    57001 gtgaaagtct agccagctcc gtttggagtt cttttttgac actcttaatt agttctttac
    57061 tagaaagtcc tacttcagaa atcaccttat ccaccacgtc catttctaac agttcatgcg
    57121 aagtgatttt catcagttct gctgcttcca tggcgcgagt accgtccttc cataaaatgg
    57181 aagcaaagcc ttctggactg agaatggcat agatagaatt ttccagcatc cagacacggt
    57241 ccgcgacagc tagagccaga gccccgcctg aaccaccttc accgataata atggcgataa
    57301 taggaacttt caggtcactc atttccatga gattgcgagc gatagcttcc ccttgaccac
    57361 gttcttccgc tccgacacca ggataagcac ctgctgtatt gataaaggtc acaactggac
    57421 ggccaaattt ctcagcctgt ttcatcaacc gcagtgcctt tcggtagcct tctggatgtg
    57481 gttggccaaa attccgtttg aggttgtctt gcaaactctt gcctttttgg ataccaacca
    57541 ctgttacagc ttggtctcca agccaaccaa taccaccaac aactgcacca tcatcacgaa
    57601 aagaacggtc accatgtaat tggataaatt catcaaaaat gcctgtcgca aagtccaagg
    57661 ttgtcaagcg actctgctca cgcgcttctc tgactatttt tgcaatattc atctaggact
    57721 ccctccatgc aatctgacta ggctagcaat cgtatctggt aagtctcttc ttttgacaat
    57781 agcatccaca aagccatgtt ctaataggaa ttctgccttt tggaaatcct caggcaagct
    57841 ttcacgaacc gtattttcaa tcacacgacg cccagcaaaa ccaaccaagc tctgtggttc
    57901 agccagaatg atatcgcctt ccatagcgaa agaagctgtc acaccaccag tcgttggatc
    57961 tgtcaaaatg gtcaggtaaa agagaccagc atttgaatgg cgtttaaccg ctgcagagat
    58021 cttagccatc tgcatgagac tcatgattcc ttcctgcata cgggctccac cagaggctgt
    58081 gaataggaca actggcaatt tttcgacagt cgcatactca aacaaacgag tgattttttc
    58141 acctacaacc gtacccatag aagccatgat aaaattagaa tccataatcc caagagccac
    58201 agtctgacct ttaataagag cagttcctgt cacaacggct tcatgcagac ctgttttttc
    58261 acgcatagat gccagtttct tttggtaacc agggaaatgc aagggatcct tgctttcaat
    58321 ccctgtaaac aattctttga aggttcccat atcaatcgtc aaagccaagc gttcttgggc
    58381 agaaatacga aaggtatagc tacagtgcgg acagatacgt tcacttccca gatccttctg
    58441 atagatggta tgcttacagc ctggacactg ggaaaataat tcatctggaa cctctggctt
    58501 agcttgaggt ttttccctaa ccgaacgatt gggattgatt cgaatatact tatctttttt
    58561 actaaataga gccattgatt ccccttttcg gtttaaactc ttaaagtcat tttattcttt
    58621 ttcttgatat ttaggtaaga aggtttccat caagaaggaa gtatcataat ccccagcaat
    58681 gacattgcga tctgaaatga gatcaagctg gaaatctgca ttggtctgca ctccttcaat
    58741 ctctaattca tagagggcac gttgcatttt catcaaggcg tcaaaacgat tttcgccgtg
    58801 tactatgatt ttggcaatca tactatcata ataaggcgga atggtataac ctggataaac
    58861 tgctgaatcc acgcgcaagc caactccacc acttggcaga tagagattag taatcttacc
    58921 tggacttgga gcaaagttaa aggctgggtt ttctgcattg atacgacact cgatggcatg
    58981 accgcgtagg acaatatctt cttgcttaac agacaaaggc tgacctgccg caatgcaaat
    59041 ctgttcctta acgatatcaa cacctgaaac aaactctgtt actggatgtt ctacctgaac
    59101 acgagtattc atctccatga aatagaaatt tctacttgct tcatcaagaa gaaattcaat
    59161 ggttcctgca ttctcatagc caacaaactc tgccgctcga acagcagcag cacctatttc
    59221 atgacgcagc gtttttccga ttgcaatcga gggactttct tccaaaacct tttggttatt
    59281 cctttgaaga gaacaatccc gttcacccaa gtgaatcaca tgtccatgct catcacctag
    59341 gatttgaacc tcaatgtgcc gagctggata gataacccgt tctatgtaca tggcaccatt
    59401 gccataattg gccttggcct cactagaggc agtttcaaag gcagaaacga ggtcatctgg
    59461 tttttcaacc ttacgaatcc ctttaccacc tccacctgct gaagccttga gcataacagg
    59521 atagccaatt ttttcagcaa caatcaaagc ttcttcagag ttatgcactt ctccatctga
    59581 acctggtata acaggcacac ctgctttaat catctgagca cgcgcattga tcttatcccc
    59641 catcatatcc ataacatgac cagatggacc gataaacttg atacctactt cttcacacat
    59701 ggtcgcaaat ttggaatttt cactgagaaa tccaaaacca gggtgaatag cttctgcctc
    59761 agtcaagact gcagctgata gaactgcatt aatattgaga taagactctg ttgccttgcc
    59821 aggaccaata caaactgctt catctgccaa aagcgtatga agagcttcct tatcagcagt
    59881 tgaataaacc gctaccgtcg caatccccaa ttcacgtgcc gcacggataa tacgaaccgc
    59941 aatttcacca cgattggcaa ttaaaatttt tcgaaacatg gagaacctcc ttagttccca
    60001 attgcaaaag taaggatacc actggctgca agcttgccat ccacttcagc ctttgcttca
    60061 accacagcta tggtgccacg acgttttaca aaagtcgctg tcataaccaa ttggtcgcct
    60121 ggtacaactt gcttcttgaa cttaaccttg tccataccag cgtaaaagac cagttttcct
    60181 ttattttcag gttttgataa ctccaacaca ccagcagttt gcgccaaggc ttccataatc
    60241 agaacacctg gcataactgg gtattgagga aagtggccgt taaagaaagg ttcgttaatg
    60301 gtcacatttt tgatagcaac aatggtatcc tcgctcactt ccaagacacg gtccactaga
    60361 agcataggat aacggtgggg aagagcttct ttgattcctt gaatatcgat catttgatac
    60421 gtaccaatcc tttaccaaac tcaaccattt cttcgttaga gacgagaatt tccgttacca
    60481 caccatcctt aggagctggg atttcattca tgactttcat ggcttcgata attaccaatg
    60541 tttgaccttt tttgacacta tcaccaactg taacgaaggc aggtttatct ggtccagcag
    60601 ccaagtaaac cactccaaca agtggactct ctacaagatt tccctcagta gccacacttg
    60661 cttcagctgg agctggaact tcttctgcta cagtctctgc tggagcagat gtaggagcta
    60721 ctggactcgg tgttgctaga acgggtgctg gagcgacttg agttgcaact tcaggcacag
    60781 gtcttgcttc attcttgcta aactgcaact catccgtccc atttttataa gaaaattctc
    60841 tcaaacttga ctggtcaaat tgagtcatca agtctttaat atcgtttaaa ttcatactta
    60901 tctattctcc caacgtttga aagcaagaac tgcattgtgg cctccaaaac caaaagtatt
    60961 tgaaatagcg tatggaattt ctttctccaa accttgtcca taaacgacat tagcttcgat
    61021 ataatctgat acttcacttg tcccagctgt cattggtaca aagttatgac gcatagcttc
    61081 gatggtgacg atagcttcta ctgcacccgc agcccccagc aaatgtcctg taaaagactt
    61141 ggttgatgat acaggtactt ccttaccaag aacagctacg atagcaccac tttctccttt
    61201 ttcattggca ggagttgacg ttccgtgagc attaacatag gctacttgct ctggagaaat
    61261 ctcagcttct tccaaggcta gtttgatggc cttgatagct ccctgacctt ctggatgtgg
    61321 agaagtcatg tggtaggcat cacaagtatt tccgtaacca accacttcag ccaggatagt
    61381 agctccacgt ttttcagcgt gttcaagact ttctagaacc aacatccctg aaccttcacc
    61441 cataacaaac ccattgcgat ccttatcaaa tgggatcgaa gcacgagttg gatcctctgt
    61501 agtagagaga gctgttaagg cttggaaacc agcgatggca aaaggtgtga tagaagcttc
    61561 tgttcctccc accaacatca catcttggaa accaaactta atggagcgga aggcatcccc
    61621 aatcgcatca tttgatgaag agcaggcagt attgatagat ttacaaacac cgtttgcacc
    61681 aaaacgcatg gctacattcc cagaagccat atttggtaaa gcttttggaa gagtcattgg
    61741 tttgacacgt ttgggtcctt tttcatgaag gcgaagtacc tgatcttcaa tttccttgat
    61801 tccaccaata ccagatgcaa cgataacacc aaaacgatcc ctattaagag cctctacatc
    61861 aagattggca tggtttacag cctcttgggc tgcatacaag gcatataaag aatagttatc
    61921 aaaacggttg gtatcttttt ttacaaagta tttatcgaac ggaaaatctt ggatttctgc
    61981 cgcattatgc acatcaaagt cactatgatc aaattttgta atgccaccaa tgccgatttt
    62041 cccagttgct aaactattcc aaaattcttc tggtgtattt ccgattggag atgttactcc
    62101 ataacctgtt accactactc gatttagttt cattcttttc acctctagct ttcgctacat
    62161 acttaagcca ccatcaatgg caatcacttg accagttaga taatcttggc ctgctaaaaa
    62221 tactgtcaaa tctgcaacct gctctgcctg cccaaattct ttcatcggaa tctgagctag
    62281 tgtagcttcc ttaatcttat ctgataagat agctgtcata tcagactcaa tcattcctgg
    62341 agcaatcaca ttgactcgta tattccgact agcgacctcg cgtgccacag acttggtaaa
    62401 gccaatcaag ccagccttag aagcagcata gttagcttga ccaatattcc ccatcaaacc
    62461 aacaacacta gacatattaa tgatagcacc ttctctggct ttcatcatcg gtttcaagac
    62521 tgattgtgtc atattaaagg caccagtcag attgaccttg agcacttttt caaaatctgc
    62581 ttctgtcatc ttgagcataa gagtatcttg ggtaatccct gcattgttga ccaaaacatc
    62641 tactgaaccc agttctgcaa tagcttgatc aatcatacgc ttagcgtctg caaaatctga
    62701 tacatctcct gaaatgggaa ccaccttgat accatagttt gaaaactcag cgagcaattc
    62761 ttctgagatt gccccacgac tgtttaagac aatgttggct cctgcttgag caaacttgtg
    62821 ggcgatggca agaccaattc cacgactcga acctgtaata aagatatttt tatgttctag
    62881 tttcattttt ttcctttcaa aacttctact tattttagtc tattttttta aaagtgctac
    62941 taaactcgct tgatcttcca catgagctaa gtgagtagtt tgatcaattt ttttaacaaa
    63001 acctgacaag actttccccg gtccaatctc gataaagttg cttatgcctg cttcttgcat
    63061 gaccccaata ctttcataga aacgaacggg ttccttgacc tgacgcgtca agagctgagc
    63121 aatgtcctct ttttgcatca cagcagcttc tgtattgccg actaggggac aagtaaaatc
    63181 tgaaaaactt acctgagcca gagtttcagc tagtttctgg ctagcaggtt caaggagaga
    63241 ggtgtgaaag ggacctgaca ccttaagagg aatcaagcgt ttggcacctg cttcttgcaa
    63301 aagttcaacc gctcgatcaa ctgcaaccac ttctccagca atgacgattt gtgcaggtgt
    63361 gttatagttg gctggagtaa ccactccaag ttcagaagct ttttgacagg cttcttcaat
    63421 gacctctact ggcgtattga gaactgctac catcttgcca gagtcagcag gagccgcttc
    63481 ttccatatag gctccacgct tagctaccaa ggcaaccgca tcttcaaaat ccaaggcgcc
    63541 gcttgccacc aaggcagagt attctccaag agacaaacca gcaaccatat caggctgata
    63601 gcccttttct tgcaataaac ggtagatagc aaccgaagtc gctagaatgg ctggttgcgt
    63661 atagcgggtc tgattgagtt tgtcttcttc cgtatcgatg agataacgca aatcataacc
    63721 tagcacctga ctcgctcgat caatcgtttc tttaacaatc ggatactgat catagaaatc
    63781 ccgtcccatc cctagatact gggcaccttg accagcaaat aaaaaggctg ttttagtcat
    63841 ttcttacaac tcctgtccag cgagaggctt cttcttgaat tttcttagcg gctccgtaat
    63901 acaaatcttt taggatttct tcagctgttt cttctttaga aacaagccct gcgatttgac
    63961 ctgccatgac agagccaccc tccacatcac cgtgaacaac tgctttggct agggcacctg
    64021 ctcccatttg ttcaaagatt tctaaatcag gatcttcctg cttaaaggca tctttttcag
    64081 ccagttcaaa atctctagtc aactgatttt taatagcacg aacagcatga ccaaagtgct
    64141 gagctgaaat cgtagtgtca atatcccttg cttttaaaat tttctccttg tagtttggat
    64201 gggcattcga ctcttttgca actacaaacc gtgtccccac ctgtacagcc tctgcaccta
    64261 gcataaagcc agccgcagca ccttcaccat ccgcaattcc tcctgcagca ataacaggaa
    64321 tagatacagc tgtggctacc tgtcgcacca aggtcatggt tgttaattta ccgatatgcc
    64381 ccccagcttc cattccttct gcaataacag cgtctgcacc gattttttcc atgcgtttag
    64441 ctaaagcgac actaggaacg acaggaataa cgattatccc agcttcatgg aaacgttcca
    64501 tatacttgct tggatttcct gctcctgttg tgacaacttt aacaccttct tcaataacga
    64561 gatccacgat atcttccaca aagggagata agagcatgat gttgacccca aagggtttat
    64621 cagtcaatga tttgatttta tcaatattgg ccttgacaac ttctttcggg gcatttcccc
    64681 caccgataat tcctaatcct ccagccttgg aaacagcccc tgccaaatca ccatcagcaa
    64741 cccaggccat ccctccttgg aaaataggat agtcaatctt caataattct gtaatacgcg
    64801 ttttcatagt gcctccaacc ttccttgctt acgtaatagt tcgatttcac cataatttga
    64861 cagtcaaact attacctaaa caagagggag tgggtttctc cctactcctt ctactaatat
    64921 tctgcttatt ttgcttgctc ttcaacgtaa gcaaccaagt caccaactgt tttcaagtca
    64981 ttttctgctt cgatttggat atcaaaagca tcttcgattt ctgagattac ttggaacaag
    65041 tccaatgaat ctgcgtccaa atcatcaaaa gttgattcaa gtgttacttc tgatgcgtct
    65101 tttccaagtt cttcaacgat aatttcttgt actttttcaa atactgccat gataggactc
    65161 ctttaaaata aatagttttt ttataacaat gtgttcacca catgattacc taaattgtaa
    65221 gaatgagcgt gccccaggtc aaacctccac cgaagcctga tagaagaaca gtctggctac
    65281 catctaaagg gatgagacct tgttctacac actctgaaag taaaatcggg atactggctg
    65341 cactggtatt gccatattcc atcatattgg ctggaagttt ggctcggtca acaccaattt
    65401 ttctagccat cttatccaaa atacggtcat tggcttgatg aagtagcaga taatccaagt
    65461 ctgtcacctc tataggagat tcatcaatag tctgcttgat agacttggct acatctcgaa
    65521 tggcaaaatc aaagactgtg cgtccatcca tcttcaaaaa cgaatctgca ctttcttgat
    65581 ctgaaaatgg agaatgcaaa cctgaatgcc cataagttaa acactcgctg cgacttccat
    65641 cgctattgag actctcagct aagaaatgct cttgctcgct agcttctaac aagacaccac
    65701 cagcaccatc tccaaacaac acagctgttg atcgatccga ccaatcgact gccttagaga
    65761 gggtttcact accaatcacc aagccttttt gaaagcgacc agaagcgata aacttttcag
    65821 cagttgaaag agcaaataca aatccactgc aagccgcggt taagtcaaaa gcaaaggctt
    65881 tattagcacc aatattagct tgaacacgag cagctgtaga gggcatcatc gaatctggag
    65941 taatggtagc taggatgata aaatccagtt cttctcctgt tattccagct tttgccatca
    66001 gtttcttagc aacctctgta gccaaatcac tggtagattc tgttcttgaa atatgccttt
    66061 gtcgtattcc cgttcgactt gaaatccact catcattggt atccataatc tgagccaagt
    66121 cgtgatttgt aaccacttgc tctggcacat aatgagcaac ctgacttatt tttgcaaaag
    66181 ccattatttc aaatcctcca aaaattggta aagattagtc aagcctttac ccatgacagc
    66241 aatttcttcc tcgctcatgc catcaataat tttttctacc atggccttgt ggaagcgttt
    66301 atgcagtcta tgaatcaagc gacccttctt tgtcaaatgc agatgcacca cacgacgatc
    66361 ctgttctgac cgaactcgct caatgtagcc cttacgctct aaattgttca aacttgtcgt
    66421 aacagttcca agagttacca ttaactcttt tgacacttga cttggagtca catctggagc
    66481 cttaccgatg acatcaattg tatgcatttc tttgatggag atatccttaa aacgactacc
    66541 tctcaagttc acttcctcaa ttacaaggac attgttaaat atagatgtta aatattcatt
    66601 gattcgttgg tagtccattt ttcatatccc tccttcttca aaaaactttt acaatcaaaa
    66661 catttgacag aaagaattat atcaaaattc aaagaatgat gcaagtattt tttattttcc
    66721 tgtaaattta ggtcttcttc tctccgaatg agctcgcact ccttctttga aatcctctgt
    66781 ttgagctaag gatttctgta ggttcagttc taaagtagcg taaccctgcc agtctttaaa
    66841 ttggctctcc caaaccaact tcttaatggc agcataggaa ttacttgaag cacgtcttaa
    66901 ttttttaaga agctgttctc tcgtcttttc aagtttttca gcttcagaaa cgcggtaaac
    66961 caacccccat tctagggctt tttctgccgt taaagcctct cctgtcatag ctaattgagc
    67021 agcacgcgtc acaccgatac tgcggctcaa gagatgaatt ccccctgcat ctggagccaa
    67081 accaacacca acaaaggctt ggataaactt agccttatcc gtcgccaaac agaaatctgc
    67141 cgcaacagcc atattcgctg cggcacctgc aacagcaccg tcaacttcca ttaaaacagg
    67201 tttggctatt tgcttgattt tataagaaat cgtattgacc aactctgcga tttttgtcaa
    67261 tgatggaata tcatcctcat ccactgcccg cttcatctct accaaatctc ccccaactga
    67321 gaagaccttt ccattggcat tgattaagat aaaatgcaca gctggatttt cttctgccaa
    67381 agtcagagct tctaaaatct cctcacacat gggaatatga aaaccatttg cgacctcagg
    67441 acggttcaag gtaaggattg ccaagtcctc ttcaagctga taaataatgt gttccatcag
    67501 ggctcctttt tattttataa gcagtttata ctcttcgaaa atctcttcaa accgcgtcag
    67561 cttccatctg caacctcaaa acagtatttt gagctgactt cgtcagtctt atttacaacc
    67621 tcaaagcagt gctttgagca gtctgcggct agcttcctag tttgctcttt gatttcattg
    67681 agtgttaaat tatttcactg tcaaagtata tcttttttag gagcagaaag caagaaaaaa
    67741 tcgactgaaa gtgtctcagc cgataagaaa ggctcgcttt aggctagaaa gcatcttatt
    67801 ttcttcattg aaaaaagcct ttctttctgc tataatcgta taaaatactt actttaggag
    67861 ttcttatgaa agttgttaaa tttggaggta gttctcttgc ctctgctagt caattagaaa
    67921 aagttttaaa catcgtcaaa agcgattcag agcgtcgttt tgtagtcgtt tctgcgcctg
    67981 gtaaacgcaa tgctgaagat actaaggtta cggatgccct gattaaatac taccgcgact
    68041 atgttgcggg taacgatatt agcaagagcc aaagctggat tatcgaccgc tatgctgcta
    68101 tggttagtga attgggacta aaaccagctg tgctagaaaa aatttctaaa agcattcacg
    68161 ccttggccac tcttcctatt gaagaaaatg aatttctcta cgatactttc ctagcagccg
    68221 gtgaaaataa caatgccaaa ttgattgctg cctactttaa ccaaaatggt atcgatgcac
    68281 gctatatgca ccctagagaa gctgggattg tggtcacaag tgaacctggt cacgctcgca
    68341 tcattccatc aagttatgac aagattgaag aattgacaaa caccaatgaa gtccttgtca
    68401 ttcctggttt ctttggtgtc actaaggaaa atcaaatctg tactttctca cgtggaggtt
    68461 ctgatattac aggttctatc attgctgctg gtgtcaaagc cgacctctat gaaaacttta
    68521 cggacgttga tggtatcttt gcagcccacc ctggtattat ccaccaacca cactcgattc
    68581 ctgagttgac ctaccgtgaa atgcgcgagt tggcctatgc aggcttctca gtccttcatg
    68641 acgaggctct tcttcctgcc taccgtggaa aaattcctct ggttatcaag aataccaaca
    68701 accctgacca tccaggtact cgtatcgttc taaaacacag taatgatgaa tttccagttg
    68761 tgggaattgc tggtgactca ggctttgtca gcattaacat gtcgaaatac ctcatgaacc
    68821 gtgaggttgg atttggccgc aaggttctgc aaatcctgga agaacttaac atcggttggg
    68881 aacatatgcc aacaggtatc gacgatcttt ctatcattct ccgttctcgc caactaactc
    68941 ccatcaagga agaagaaatc ctgcgtcagt tggttcaaaa ggctaaagta gatcatgcag
    69001 aaatcgaaca cgacctttct atcattatga ttgttggtga aaaaatgaag agccacatcg
    69061 gagtgactgc tactgcgaca cgcgctctat ctgaaaacaa aatcaacatc cagatgatgt
    69121 ctcaaggttc tagtgaagtt tctattatgt ttgttgtcaa taaagaccaa gagaaagcag
    69181 caattaaagc cctctacaat gccttttttg gagaaagtaa ggaagactaa gcatggccca
    69241 atcacttaac aaaacagtac tcctcagtac gacaggcact tcctacctct ctatcgctgg
    69301 gaaagttggg aaattccttg tcggagatca ggctttggaa ttttacccag atgtcaatgt
    69361 cgaacaattt atccagattc cttggagcca tatcaatcag attggagcca atgtcactgg
    69421 acgcaaaatc agccgccact tcgaagtctt tacagacaaa ggaaaattcc tctttgcttc
    69481 aaaagactca ggtgccattc tcaaaattgc acgcgaaaaa ctaggcaatg acaaggtcgt
    69541 caaacttccg accctgattc agacaattag ccaaaaattt aaaaatctat ttgcaaaaaa
    69601 gtagaaactt tagtataatc atagcaacgg ataagtaggt tatcttcttc tttcagaaag
    69661 tctgcgggta ctgcgagcag atagggggga taggtgaaat tctaccgtta gtaacaatta
    69721 catacacaat caagtgcaca cctgtgaagt tggatggaac cgtggccctg ccactccaac
    69781 gttttgtcag gcgtgctttt ttcataaagg agttcttatg ttagatatca aacgtattcg
    69841 tacagatttt gaagctgtcg cagaaaaatt agctacacgt ggtgtagagg ctgctgtctt
    69901 gaatgaaatg aaagaaatcg atgctaaacg tcgtaacatc ttggtcaagg ttgaaactct
    69961 caaagcagaa cgtaacacag tttctgctga gattgcccaa gctaagcgca acaaggaaaa
    70021 tacagatgac aagattgctg ccatgcaaaa tctatctgct gaggttaaag ccttggatgc
    70081 tgaattggca gaaatcgatg ctaaattgac agaatttaca acgactcttc caaatatccc
    70141 agctgacagc gttcctgttg ggactgacga agacgacaat gtggaagttc gccgttgggg
    70201 tactccacgc gagtttgact tcgaacctaa agctcactgg gatctcggtg aagaccttgg
    70261 tatccttgac tgggaacgcg gtggtaaggt aacaggcgct cgcttcctct tctataaagg
    70321 cctcggtgct cgtttggaac gtgctatcta caactttatg ttggatgaac atggaaaaga
    70381 aggctatact gaagtcatca caccttacat agtcaaccat gattctatgt ttggtactgg
    70441 tcagtatcca aaatttaagg aagatacttt tgaactcagc gataccaact ttgtcttgat
    70501 tccaactgct gaagttcctc tgacaaacta ctaccgtgat gaaatcttag acggcaaaga
    70561 tcttccaatc tacttcactg ccatgagtcc gtcattccgt tctgaggctg gttctgccgg
    70621 tcgtgatacg cgtggcttga tccgtttgca ccaattccac aaggttgaaa tggtcaaatt
    70681 tgccaaacca gaagaatctt acgaagaatt ggaaaaaatg acagccaacg ctgaaaacat
    70741 tcttcaaaaa ctcaaccttc cataccgtgt cgttgctctc tctactggag atatgggctt
    70801 ctcagctgcg aagacttacg acttggaagt gtggattcca gcacaaaaca attaccgtga
    70861 aatctcaagc tgttcaaaca cagaagattt ccaagcccgt cgtgcccaaa tccgttaccg
    70921 tgatgaagca gatggcaagg tgaaactcct tcataccttg aacggttctg gacttgcagt
    70981 tggacgtaca gtggctgcaa ttcttgaaaa ttaccaaaat gaagatggtt ctgtgaccat
    71041 cccagaagca cttcgtccat acatgggtgg agctgaagtc atcaaaccat aaaaaataag
    71101 gtttagctat ttctagctag accttttttc gtaaccaaat cagataagca cctagtacaa
    71161 agaataaaat agttaggcat ataatggttt cagccaatac caggtaatcc agaaatggaa
    71221 gtttcaaaat tccctgagcc atcttgagcg aggtcgctgt gataatggtt gggaaggtga
    71281 gggctgagaa ggctggttga aaaccttgtt ttaaaatgtt gggcagacga gttaaaacaa
    71341 agaaaaagaa ggattgagaa gccaaaatca tgacaatcaa gacccaagtc ggcaggctgg
    71401 ttcctcctac tcgaactaga gaagccaaga gtagagagaa aggagcacag tagattcctt
    71461 cttgtccaag caaggctagt gggagtggat gtttctttaa atcgctataa ataaggggat
    71521 agagatagaa ggtcaagaga aaaccaaaac tcaaggtcgc ataggcaatt tcgataatac
    71581 ctaccagagg ataggtcaag gcagccactg ctatccccac atagagaacc gtccaacttg
    71641 gagtggcatg aaccctccgc cctgaacaag caaacttgat ggtaaaacca gcaatcaagg
    71701 tcaaatccaa gagaaatgaa aaccaccaaa tcccttgtgc taccaaagga agataagaga
    71761 atacgcgaaa gacataggtc gataaaatca tcccagccat aggaaaggtt gccattcctg
    71821 acaaaagagg gggcttggtc aattcttgct tggtttcttt ccaattaaag agatgcagaa
    71881 ttagaaagta aatccataaa accaaaccag tcagactaaa aagatgggat agaaccggca
    71941 acgtatctaa aataagattt ccagctcctg ccaaacctag caaacaacct gaaaatacta
    72001 aggggagttt tttcatccta acctccaata atcatgttag tttcagtata acataaaagc
    72061 gcttaaatga ggatttaaaa aaacgaagtc cgcttatttc agacttcatt ttactcagat
    72121 atgaattagg cataaggttg caattctgga ttaattggtg tattagctaa gttgttggca
    72181 tagttacaga ggattgctag gctgacacca aaaaccacat ccaaggcatt ttgttgagtg
    72241 tagccagctt ctaaaaactc agacaaggct tcatctccta cacgaccctt ggtattgata
    72301 actgccaagg taaacttagc tagggtatcc aatttaggat ctgtttcaat tggagtacga
    72361 ttgcgaagag cttgaatcaa gtcatcattc atctggattt gtttgatgga aaaggctgtg
    72421 tgacctgcga cacagaaggc acaaccattg gtcacggctg ccgtgatttg caccacttca
    72481 cgctcaacgg gtgtcaggct gttgcgacgg tggatagatg agacaatttg gtaggcttct
    72541 aaaacagtcg gggcattggc caagagaccg attaggttgg gaatatagcc attgttgtct
    72601 ttttctactg tttcaagaat ttctttcact tctgctggtg ctgactctac tgtatggata
    72661 gtaaatgttg tcataagata cctcttttct tattattgac actaatatta ttggaaaatc
    72721 ttataaaatc ctgattccta agtttatcta agataaagct ttattctctc ataagatttt
    72781 cgttgttata ttagtttatc acacttccaa tcacttgcat aatatatatt atatatcagg
    72841 ctgataaaaa ttatttatag gcaaaaaaat cacacgagct gtgtgattcc attatttgtc
    72901 aaaatacttt ttagtttcag caataacgac tggcgacaag accaagaggg caatcaagtt
    72961 tggcagagcc atcaaggcgt taacgatatc tgcgataatc cagaccatat ccaactcgat
    73021 aaatcctcct aacaagacca tgagcacaaa aaacacacgg tagagccaga taaagcgagc
    73081 cccaaagagg aactcaaaac agcgttctcc gtaatagttc caacctagaa tcgttgtaaa
    73141 ggtaaaaagt acaaggaaga tggtcaagag ggcaggccca aagtgtgaaa agactgttga
    73201 gaaagctgac tgagtcaagg caaccccatt caagtcacca ctccaaactc cagttaccaa
    73261 gatggtcaaa ccagttagag tacaaatgat gagggtatca ataaaggttc ctgtcatgga
    73321 aatcaaacct tgctctactg gttcatttgt cttggcagct gcagctgcaa taggagcaga
    73381 acccagacca gattcgtttg agaacacacc acgcgccaca ccattttgaa tagccatccg
    73441 aacgctagca ccagcaaatc cacctaccgc agcaagggga ctaaaagctg aggtaaagac
    73501 taaagcgatt gtgccaggga tttttccgat attaaagaaa ataactgtaa gagttcctaa
    73561 gatataaatg agggccataa aaggaacaac agtagttgaa accttagaaa tagacttgag
    73621 tccaccaaag actgcaatcg ctacaaagac agacaagacg agagctgtga tggctggcga
    73681 aatcgtcgtt gtattttgga tagattctgt aatcgagttg acttgggtga aggttccgat
    73741 tcccaagaga gcaaccaata ctcctgctac tgcaaacaaa acagcaagtg gtcgccactt
    73801 ttctcccatc cctagaagga tatagtgcat gggacctccc gctactgcac catggtcgtc
    73861 cttggtgcgg tatttgatgg ccaagagtcc ttccgcatac ttggtagcca ttccaaagaa
    73921 agccgccatc cacatccaaa atagagctcc tggtccacca accttgatag ccgtcgcaac
    73981 tcctatgata tttcctgttc caacagttga tgccaaggct gtacacagag ctgcaaaact
    74041 ggatacatca ccatgtccct tatcctggat aaaaataagc tgaaaggcct tgggcagacg
    74101 caaaacctgc aagagtccta gccgcatggt taggtaaatc cctgttccga ccaataaaat
    74161 caagaggggc ggtccccaag caaaagcatc gattgattta agcaattcta acattttctt
    74221 ctcctatcgt ttcaacccca aaagaaagag cacatgcaag atacatgtac tctggaatgc
    74281 ttagataaat gctaaaaagc ggtctatcct agctctgtcc ttttacctga gagtttgagc
    74341 agttgcctgc cttgcccctt cggtgccttt acggtctctc cagagttccg tccatttaca
    74401 gtcatggaaa atcaaacgat tccccacttc tattaaactt cattcggtgt tggtatttaa
    74461 ttgattctaa ttttacaaaa aatgttggct tttgtcaatg tgtttattag taaaaattag
    74521 ttcaacagtt tttactttat aaagtccaga atactgctat cctttaaaag tgacaatagt
    74581 cgcaccactg cctccagcat tttgtggggc atagccgaaa ctcttgacat gtttgtttct
    74641 ttgcaagtat ttggtaactc cttcacggat gactcctgtt ccgataccat ggatgatatc
    74701 aacttgagcc atattgttaa gcaaggcttg gtcgatgaag gtatctagct cattcatggc
    74761 ttcttcatag cgcttgcctc gaagatccag tctagcttga ggtcctcgcc cagaagttcg
    74821 tttcacaaca ttgacctgtt tcttcttgac tggtttttct tgctgggctt gaacaagatc
    74881 aaactctttc tcttccaagg tcatcttaat caagccaatt tgggcttccc agcggccgtc
    74941 cttgagttga ctggtcaagg taccacgctg accataactg agaaccacga tatcatctcc
    75001 cacctttgga gctcgttttt tcttggcctt ttgaaggacc ttgtttttag acaagtccac
    75061 tttttcagga gccaattttt tcaacttggc cttggcttca atgatttcgt ggggcttgag
    75121 ttgggattta ctgtggagat ttttgagaat ctggtcactt tcacttaggg ccatatccac
    75181 aatctcagca gcctgttcac gcgccttgtt aagctcggtt tccttttcac gattaagctc
    75241 gttgtagagt ttttttagcg cacggttcat cttgagattt tcttgctcca cctcacggat
    75301 attgtccaag cgtttgcggc tttccagcgt ctgctcttct aattgctcaa tgatacgatt
    75361 gacgtcattg tcctgatcga tctgctgact ggcatctcct acgataactt cagataggcc
    75421 tagacgtttg gcaatttcaa aggcattact tcggccagga acaccctgca taaagcgata
    75481 ggtcgggcga agagttgcag tatcaaactc catactggca ttttgcacaa aggctgtctc
    75541 aataccgtag gccttgagtt ctggatagtg ggtcgtcgcc atggtcttga tttgacgcag
    75601 gcgaaggtcc tccagaatag ccatggcaag ggctgctccc tcttggggat cagtaccagc
    75661 ccccaactca tccaaaagta agagtgaatg ttggttgacc ttgccaagaa tatccacgat
    75721 attggtcata tggctagaga aggtagacaa gctctgctca atagactgct catctccaat
    75781 atcagcaaag atttcttcaa aaataccaac acgacttccc ttgtctgcta aaatcggcaa
    75841 tcctgactgg gccatgacct gtgtcaagcc cagagtttta agcatgatgg tcttcccacc
    75901 tgtattggga cctgtaatga caatagctgt taaatcttga ccaaaataga catcatttgc
    75961 gacggcattt ttgaccaaag gatggcagac atggagcagt tgaatctctt gattttctga
    76021 cagctgaggc acgactgctt gtctttcttg aataaatcga accttggcac gaatcaagtc
    76081 cagatgaccg ataatccaag cgtcattagc aatctcagcc gcatgagggc ggacacgctc
    76141 agaaatttct tggagaatgc gaagcatttc atagcgctca tctgctcgca gactagcaat
    76201 ttcttcgctc agtttgacta cctcacgtgg ttcgatatag acggtgtttc cactagcaga
    76261 aatatcatga acgacacctg caatcttatt gcggtaggtg tttttgactg gtaaaacctg
    76321 acggccattt ctgctagcaa caattccttc cgtcaacatc tgcccttttt gcttgagcaa
    76381 gtcttgtaaa acatcgcgta cctgactctc gctatcatgt atttttcgac ggattcgcgc
    76441 caattcttca ctggcaaaat tttcaatgaa acccgcatca ttaaaggcct gaagatttcc
    76501 ttgtaattgc ggaaaatcat gtaatttctc aaaccaaagg gctaattctt ccaagctgac
    76561 attttccaga ttggcgtaaa aactttgaag ttctcggctg gcaagaagca cgcgtttcaa
    76621 gagtaggaac tcctcgatat tgagatccgc tcccatctcc aacctcttgc agactcctgc
    76681 aatttcctta gttgagagaa tagtaaaatg cggttgctcg acgaaaagag cctgcatttc
    76741 tttcatctca gcaaaagcct gtttgatttt atctgctttg gcagtcggag ccagctgtct
    76801 caattgctcc aagccctgct cggtcaacaa atgaggctca aacaaggcct tgaccttatc
    76861 gaactctaat gtttctaata ttttcttatt catctttatt tccttgtctt tgaatgtcta
    76921 ggtgtggtag ctttttacat tctgatagat tcgagtcaaa tctgtaaaca aagggctagg
    76981 aaaactcctg ccctttttat ccgattaaat ttgtcaccca gatttgtttg agccaactgg
    77041 ttgttatcgg tatgctctgg atgatgtgtt ttgcgacgat actcttttca agaggatttt
    77101 gtataactgc catagggatg gtcgccaaga ttgtcaaggc catttgcaag acaaataagg
    77161 tcaccaacat ggacaagata cctgctgaaa cttggaacaa cttaccaccc agttttttgc
    77221 taggaatcaa gtgtaagaga agaccaagca aacgaccaat gctatagaca atcccaaata
    77281 caagcaagta gccgatacct gcataaaaga ccttatccag ctgaaagagt tgatccgatg
    77341 ggaaaaagaa agtcccctga ccttcctgcg aatttgcata agggagcaat aaatggaatt
    77401 gctctccaag ccccttataa aactggccag ccataaaagc cgatgccatg gctgaaatca
    77461 ggtaataaac ctgtaagagc aggcctctcc gatagccgat ataaaatccc caaaccaaga
    77521 ccaatagaag aaggaatgaa atcataagga atcctcaatc ttgctctgtt cttgcttaca
    77581 agtcacaagc ttgtgacgga gttcttctag ctcttgctcc ttatcgtcaa attcaatctc
    77641 acggctgagc tgagttgata aacagttgac tgccaacaaa agagcgattg tttcatcatc
    77701 tgcgctaggc atttgttctt taattgcttg gtatttttct gtcgcaacct tagcgatttc
    77761 ctccataaaa aggttatcat gttcgcttgt caaggttaac gtttttttcc cgaatgtaaa
    77821 tttgaatcga tttagatttg ccataaaatt cacctcacga tattatacca aaattcgcta
    77881 attttgtcag tttttacaaa ttttactgct tttgtggtac aatagaaact atggcaagta
    77941 tcacactcac accaagcgaa aaggatattc aggcttttct tgaacactat caaaccagtc
    78001 tggctcctag caagaatccc tatatccgct actttttgaa actacctcaa gcaacggttt
    78061 ctatctatac ttctggaaaa atcttgcttc agggtgaagg ggctgaaaaa tacgccagtt
    78121 tctttggcta tcaagctgta gagcaaacca gcggacaaaa tcttccttta attgggacag
    78181 atgaggtggg aaatggttcc tactttggtg ggcttgcagt tgtggctgcc tttgtcacac
    78241 ctgaccagca cgacttttta cgaaaactcg gtgtggggga ttctaagact ctgaccgacc
    78301 aaaagatccg tcagattgct cctattctca aggaaaaaat tcagcaccag gcactccttc
    78361 tctcacccag caagtacaac gaggtcatcg gagaccgcta caatgctgtt tcggttaagg
    78421 ttgccctcca taatcaggct atctatctcc tccttcaaaa aggtgttcag cctgagaaaa
    78481 ttgtgattga tgcctttacc agtgctaaaa attatgacaa gtacttggca caagaggcca
    78541 atcgtttcag caatcctatc agcttagaag aaaaggctga gggcaaatac ttggctgtcg
    78601 cagtttcttc tgtcattgcg cgtgatctct ttctggaaaa tcttgaaaat ctgggacgag
    78661 aactgggtta tcagctccca agtggagctg gaacagcttc tgacaaggtg gctagccaga
    78721 ttttgcaagc ctatggtatg cagggactca gcttctgcgc caaattgcac tttaaaaaca
    78781 ctgaaaaagc gaaaaaacgc ttagaaaggt aagttatgaa ttcatttaaa aatttcttaa
    78841 aagagtgggg attgttcctc ctaattctgt cattactagc tttaagtcgt atcttttttt
    78901 ggagcaatgt tcgcgtagaa ggacattcca tggatccgac cctagcggat ggcgaaattc
    78961 tcttcgttgt aaaacacctt cctattgacc gttttgatat cgtggtggcc catgaggaag
    79021 atggcaataa ggacatcgtc aagcgcgtga ttggaatgcc tggcgacacc attcgttacg
    79081 aaaatgataa actctacatc aatgacaaag aaacggacga gccttatcta gcagactata
    79141 tcaaacgctt caaggatgac aaactccaaa gcacttactc aggcaagggc tttgaaggaa
    79201 ataaaggaac tttctttaga agtatcgctc aaaaagccca agccttcaca gttgatgtca
    79261 actacaacac caactttagc tttactgttc cagaaggaga ataccttctc ctcggagatg
    79321 accgcttggt ttcgagcgac agccgccacg taggtacctt caaagcaaaa gatatcacag
    79381 gggaagctaa attccgcttc tggccaatca cccgtatcgg aacattttaa gaaacctaag
    79441 aggccgagaa tcaccaatct cagcctcttc ttctatcgtg agaagtgatt gtttattgac
    79501 aaatactcaa tgaaaatcaa agaacaaact aggaagctag ccgtaggctg cttaaaacag
    79561 tgttttgagg ttgcagatgg aagctgacgt ggtttgaaga tattttcgaa gagtataaaa
    79621 taaaaacaat cccaactctc acctattcat gcaaaggaat tttatggaag tttatttttc
    79681 aggaaccatt gaacggatta tttttgaaaa tcccagcaat ttttatcgca tcctcctcct
    79741 agaaatcgac gatacggacg cagaggattt tgatgacttt gaaatcattg tcacaggaac
    79801 catggctgat gtaattgagg gcgaagacta tactttttgg gggcaaattg tccagcactc
    79861 caagtatgga gaacaactgc aaatcagtcg ttatgatcgc gcaaaaccaa ctagtaaggg
    79921 cttggtcaag tacttttcaa gtagccattt caaggggatt ggtctcaaga cagctcagaa
    79981 aatcgtggat acctatggcg aaaataccat tgacgaaatt ttgcaacacc cagaaaagtt
    80041 agaaggcatc gcaggactct ctgccaaaaa tcgcgaggct ttcgtctcca ctctccgtct
    80101 caactacggt acggagatgg ttttggccaa actagccaac tacggcattc ccaacaaact
    80161 agcctttcag attcaagact tttacaagga agaaaccctt gatgtggttg aaaattatcc
    80221 ctaccaactg gttgaggata tcaagggttt gggctttacc attgctgacc aactagctga
    80281 ggaactaggc atcgaaagtc aggctcctga acgcttccgc gccggtctag ttcacagtct
    80341 ttttcaggcc tgtatggaaa caggagacac ctatgttgaa gcacgggatt tgctggaaca
    80401 aacccttact ctccttgagt cttcccgtcc cgtggaacta gaccccagcc aagttgccca
    80461 agagctctcc tacctgatcg aagaagacaa ggttcagcag attgatacca agatctttga
    80521 caacagcctc tttttcgctg aggaaggcat ccgcagtcac ttggttcgta tccttgaaaa
    80581 aggaaaacag aagagtcatg atttagaaac cattcaaaaa catatcacta ctatcgagga
    80641 agagctggga attgagtatg ataacattca aaaacaggct atctgtgacg ctatccagaa
    80701 caaggtcttt atcctgacag gtgggcctgg tactggtaag acaactgtta tcaatggaat
    80761 catcgctgtt tatgcccttt tagaaggact tgacttcagg aagaaaaaca atctgcccat
    80821 tcttcttgct gctccaactg gacgagccgc tcgccgcatg aatgaattga caggtttgcc
    80881 tagcgcgacc atacaccgcc acttgggaat gacaggtgac gatgatacca gtcatctgga
    80941 agattaccta gatgctgact ttatcatcgt ggatgaattc tctatggtgg atacttggct
    81001 ggccaatcaa ctcttctcca atatctcttc taacagtaag atcctcatcg tgggtgacag
    81061 tgatcagcta ccttctgtca gtcctggaca ggttctagcg gatctgcttc atattccttt
    81121 gattcctcag actcgcttgg aaaaaattta tcgacaaagc gaagaatcaa ccatcgtcac
    81181 cctagctagt cagattcgac agggcatctt gccagctgat ttcacccaaa aaaaagctga
    81241 ccgttcctac tttgaaattg ctagtggcca tattcctgcc actattgaaa aaatcttagg
    81301 tgccgccctc agaaatagta ttcctgcccg tgatatccaa gttctggctc ctatgtaccg
    81361 agggacggca gggattgatg ctatcaatca gctcatgcaa gacctgctca atcccccaca
    81421 aaaagatcaa ctcagttttg aagctcctca gtgccactat cgtaagggag acaaggtcat
    81481 tcatttggtt aacgatgctg aaatcaatgt ctttaatggg gatttaggag ctatcacaga
    81541 cctgattcct ggtaaataca ccgaatcgaa acaagacgag attgtcattg attttgatgg
    81601 taatgaagtc tcttaccccc gtaacgaatg gtacaagatt cgcttggcct atgccatgag
    81661 tattcataag tctcagggaa gtgagttccc agttgtcatc ctaccgatta ctagtgctag
    81721 ccgacgtatg ctggagcgaa atctcatcta cacagccatt acacgtgcca aaagcaaact
    81781 catcttacta ggcgaattac aagccttcga ctatgctacc caacacatcg gaactgcccg
    81841 aaaaacctat ctgattgaac gcttcagtga tctactggag aatgttgaag aaaagcaaca
    81901 agctgtctct gaaacagtca catcaagtgc ctctgaacaa tcctacatcc taaccgaaga
    81961 aaactgggac agcattccag ccatgattgg gattacagac acagacctca aagagatttt
    82021 tggaaaatag tgcatcagaa aaaccaccaa ttcaggtggg ttttctgttt attaagatta
    82081 ttttactgtt gctgtgcttg tgatcaattc aacagctttt ttgatagtga tatcatgttt
    82141 caacatgtca gctgaaagca agttttgaac ttgtgcaact tccatgttgt agtctgctgc
    82201 caattgctca acttcttttt ggatttcttc ttctgaagca tcaaatcctt cagctttggc
    82261 aactgcttcg ataacaaggt tagtcttagt acgtgactca gcttctgctt ggtattggtt
    82321 gtgaaggtct tcttgagtag ttccagtgat ttggaagtac atgtcagggt tgatcccttg
    82381 acgttgcaaa ttcccaagga attcatttac tgaacggtga acttcttcat ggatcatttc
    82441 ttctggaagt tctacgattt cagcattttc tacagctgta tcaattgctg caccttcaac
    82501 tgcatctttg taagcttctt ctttagcagc agccaattct ttgcggtatt tttctttcaa
    82561 gtcagcaagt gtttcaactt cttcatcaat gtcttttgca agttcatcgt caagagctgg
    82621 aacttcttta gcttttactt cgtggatagt tgtcacgaat ttagcttctt tacctgcaag
    82681 gtcttctgct tggtagtctt ctgggaatgt tacgataaca tcaacggttt cgccagctga
    82741 gtgacctacc aattggtctt cgaaaccagg gatgaattga cctgaaccaa gtccaagtga
    82801 gaagttttca ccttttccac cgtcaaattc aacaccgtcg atagaaccaa cgaagtcgat
    82861 cacaacagtg tcgccgtttt cagcagcagc ttccttgata accaattcag ccaggttgtt
    82921 gcgttcgcgt tcgatacgct cttcgacatc agcgtcagtt acttcttttt ctacatcaac
    82981 tgatacttca aggtttttgt agtcacccaa ttttacttca ggttttgtaa cgacttcagc
    83041 agtgataacc cagtcttgac ctttttccat tgaagttacg tcaatttttg gttgggcaac
    83101 cacttcaaga ccagcttctt ttacagctgc ttcataagcg tttggcaaaa gagcgttcat
    83161 aacgtcttgg taaagtgatt cttcaccaaa tttttggtcg aagataggac gtggaaggtg
    83221 acctttacgg aaacctggaa cattaagaga tttcttcact gacttgaaga cacggtccaa
    83281 ttctggtttg atttggtctt gagagatagt gaaagtcaag acaccacggt ttgtttcttt
    83341 gttttcaaat gatacagaca ttctgtcatt tctccttaaa attttttaaa tacagtctat
    83401 tataacattt tctataaata aaatctagac taatgcagcc aattatagac aacaagcctt
    83461 tttcctaact aaaacactca taaagtatag acaattttag actactttgg atatcttttg
    83521 gttagtcatt ttccaaaact aatttatcta atttttcagt tatatagta
//
LOCUS       DBEJJV010000004        76085 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.004, whole genome shotgun sequence.
ACCESSION   DBEJJV010000004 DBEJJV010000000
VERSION     DBEJJV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 76085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.004"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            160..594
                     /locus_tag="ACL3GT_000286"
     CDS             160..594
                     /locus_tag="ACL3GT_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0516015.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQESVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            606..1796
                     /locus_tag="ACL3GT_000287"
     CDS             606..1796
                     /locus_tag="ACL3GT_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HGR0516016.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1807..2298
                     /locus_tag="ACL3GT_000288"
     CDS             1807..2298
                     /locus_tag="ACL3GT_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0516017.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2313..3092
                     /locus_tag="ACL3GT_000289"
     CDS             2313..3092
                     /locus_tag="ACL3GT_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0516018.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            3079..3897
                     /locus_tag="ACL3GT_000290"
     CDS             3079..3897
                     /locus_tag="ACL3GT_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0516019.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGENQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3897..4190
                     /gene="yajC"
                     /locus_tag="ACL3GT_000291"
     CDS             3897..4190
                     /gene="yajC"
                     /locus_tag="ACL3GT_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0516020.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            4212..6113
                     /locus_tag="ACL3GT_000292"
     CDS             4212..6113
                     /locus_tag="ACL3GT_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HGR0516021.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKFMSFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHRRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6173..7174
                     /locus_tag="ACL3GT_000293"
     CDS             6173..7174
                     /locus_tag="ACL3GT_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0516022.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7284..7619)
                     /locus_tag="ACL3GT_000294"
     CDS             complement(7284..7619)
                     /locus_tag="ACL3GT_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516023.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7630..7872)
                     /locus_tag="ACL3GT_000295"
     CDS             complement(7630..7872)
                     /locus_tag="ACL3GT_000295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516024.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7888..8082)
                     /locus_tag="ACL3GT_000296"
     CDS             complement(7888..8082)
                     /locus_tag="ACL3GT_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0516025.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8248..9198
                     /gene="rsmH"
                     /locus_tag="ACL3GT_000297"
     CDS             8248..9198
                     /gene="rsmH"
                     /locus_tag="ACL3GT_000297"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HGR0516026.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPEGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            9210..9527
                     /gene="ftsL"
                     /locus_tag="ACL3GT_000298"
     CDS             9210..9527
                     /gene="ftsL"
                     /locus_tag="ACL3GT_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HGR0516027.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            9531..11783
                     /gene="pbp2X"
                     /locus_tag="ACL3GT_000299"
                     /gene_synonym="pbpX"
     CDS             9531..11783
                     /gene="pbp2X"
                     /locus_tag="ACL3GT_000299"
                     /gene_synonym="pbpX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HGR0516028.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            11785..12765
                     /gene="mraY"
                     /locus_tag="ACL3GT_000300"
     CDS             11785..12765
                     /gene="mraY"
                     /locus_tag="ACL3GT_000300"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HGR0516029.1"
                     /translation="MFISLSAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            13329..15434
                     /locus_tag="ACL3GT_000301"
     CDS             13329..15434
                     /locus_tag="ACL3GT_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGR0516030.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(15730..16212)
                     /locus_tag="ACL3GT_000302"
     CDS             complement(15730..16212)
                     /locus_tag="ACL3GT_000302"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HGR0516031.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(16307..17791)
                     /locus_tag="ACL3GT_000303"
     CDS             complement(16307..17791)
                     /locus_tag="ACL3GT_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HGR0516032.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDATRAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            17944..19554
                     /locus_tag="ACL3GT_000304"
     CDS             17944..19554
                     /locus_tag="ACL3GT_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HGR0516033.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVEMTD"
     gene            complement(19698..21094)
                     /locus_tag="ACL3GT_000305"
                     /pseudo
     CDS             complement(19698..21094)
                     /locus_tag="ACL3GT_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            21272..22717
                     /gene="cps4A"
                     /locus_tag="ACL3GT_000306"
     CDS             21272..22717
                     /gene="cps4A"
                     /locus_tag="ACL3GT_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HGR0516034.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGVDVHNDQ
                     EFSALHRKFLFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGTDRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            22719..23450
                     /gene="cps4B"
                     /locus_tag="ACL3GT_000307"
     CDS             22719..23450
                     /gene="cps4B"
                     /locus_tag="ACL3GT_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HGR0516035.1"
                     /translation="MIDIHSHIVFDVDDGPKSIEESKALLREAYNQGVRMIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYREIHAGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVLKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKEFFVDNPRKIIMDQLI"
     gene            23459..24151
                     /gene="cpsC"
                     /locus_tag="ACL3GT_000308"
     CDS             23459..24151
                     /gene="cpsC"
                     /locus_tag="ACL3GT_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HGR0516036.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQEEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLSKLK"
     gene            24161..24844
                     /gene="cpsD"
                     /locus_tag="ACL3GT_000309"
     CDS             24161..24844
                     /gene="cpsD"
                     /locus_tag="ACL3GT_000309"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HGR0516037.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIARSFARTGYKTLLIDGDTRNSVISGVFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVIQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTAIGEVNKRDVQKAKQQLEQTEKLFLGVVLNKLDISVDKYGVY
                     GSYGNYGKK"
     gene            24860..26227
                     /locus_tag="ACL3GT_000310"
     CDS             24860..26227
                     /locus_tag="ACL3GT_000310"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HGR0516038.1"
                     /translation="MDEKGLKIFLAVIQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVISKRILDICGATIGLIL
                     FAIASLVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMRIDAEAIKEQLMDQNTM
                     QGGMFKIDNDPRVTKIGRFIRKTSLDELPQFWNVFIGDMSLVGTRPPTVDEYDQYTPE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            26233..26976
                     /locus_tag="ACL3GT_000311"
     CDS             26233..26976
                     /locus_tag="ACL3GT_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HGR0516039.1"
                     /translation="MNERMQILGVTIDPLTMKETVDAVEQYVLKKHPLHLMGVNADKI
                     NQCHEDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEILQDMLKVFKQRYPNLNVVGYRNGYFSPEDEKKIQEDIKGGKPDFVF
                     VGITSPKKEYIIQSFMDNGINAVFMGVGGSFDVLSGHIKRAPLWMQKLNLEWLFRVVN
                     EPKRLFKRYFIGNVTFIKRVLDEKRKSKK"
     gene            26951..28036
                     /locus_tag="ACL3GT_000312"
     CDS             26951..28036
                     /locus_tag="ACL3GT_000312"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0516040.1"
                     /translation="MKSENQKNNILHISRTMDIGGAERIVYQLSSDLKDEFDSVHVAS
                     TGGLWESKLLSKGVQHHKILDVDSKNPLTMVKILSSFYRIIKNNDITIVHTHHRMAAF
                     YIRLLKIINPKLIHVYTAHNVFKNKLPLYKFSLKKAYCVAVSKAVNDNLKHDVGISDS
                     TVIYNGVVFEKTDKLVGEIVNYNGIKLGCIARLSEQKGLTYLIDAMSLVKHRNITLFI
                     VGDGELRDELENKVKQLNLQKSVIFLGYRKDIVECINSFDYLVSSSLYEGFGLNAIEA
                     FMKGKTMVSSDIPGINEVVNNKNGILVPVKDDVALARAIEKLATDKKLREKLAYQAKK
                     DYETKFNYSLFLDNYRRLYRKLMGESK"
     gene            28033..29121
                     /gene="wecB"
                     /locus_tag="ACL3GT_000313"
     CDS             28033..29121
                     /gene="wecB"
                     /locus_tag="ACL3GT_000313"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="non-hydrolyzing UDP-N-acetylglucosamine
                     2-epimerase"
                     /protein_id="HGR0516041.1"
                     /translation="MKKVMLVFGTRPEAIKMCPLVNELKQNDSIKTLVCVTGQHKEML
                     EQVLEVFKVVPDYDLGIMKANQTLFTITTSILDKIQAVLEKEKPDLVLVHGDTTTTFA
                     TALAAFYMGIKVGHVEAGLRTYNLQSPFPEEFNRQTTSIIADYHFAPTEVAKENLLRE
                     DRKNIFVTGNTVIDALKTTVQDNYHHPILEWAKGSKLIMLTAHRRENLGKPMENMFNA
                     VNRILNEFEDVKVVYPIHKNPKVRELASKVFGDNERMKIIEPLEVIDFHNFMNQSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVVAGTLKLVGTEEENIYSNFKLLLEDET
                     EYNKMSKASNPYGDGMTCKRIVDIILEV"
     gene            29238..30302
                     /locus_tag="ACL3GT_000314"
     CDS             29238..30302
                     /locus_tag="ACL3GT_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HGR0516042.1"
                     /translation="MATLFALLSTLVKLFVTFDYIPKVLLQHKVTLIDILVVLFLFFQ
                     AFAAFQSQTLYLNYVGGQFFLLGLYSFLKHFLLLDCKTTIKSLFLTFILFLCVQVITQ
                     LLFPVGFDSLHPTGDNRLYFLGRKNIATPYIIVGLGGFYLLNKKMNEFISLKEIIFLG
                     LFGILSFLTQSSTAIICYGLFIFIRLLGLKENIGKLYSLVSMAVYVCFSLSIIFSQST
                     ILSTFTAIFSKNATFSGRINIWQLAIRIFEENFWFGRGLNVNFNAWTNGIIVNSAHNT
                     LLDILARTGIFPGVLFIVLLMNLFLGKYRIESKTLLAMLASFMIYITMETSSMSILLL
                     IIVLCVYWPRGEEKLHEQVT"
     gene            30286..31155
                     /locus_tag="ACL3GT_000315"
     CDS             30286..31155
                     /locus_tag="ACL3GT_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HGR0516043.1"
                     /translation="MSKLLNTIYYRLFRLYKKIYLQVFSKKTVDILGEKANLENELIV
                     SFTTIPSRLNYLPSMIKSIFNQTIIPNRFIMYVYKDEFEGINLESILELEIKNGLEIV
                     YVDENLRSHKKYFYAMKDNPNSIVVLVDDDIIYPRNTIKKLIASYRIYPQCVSAMRCH
                     RIKLFSDGSLYPYNQWEYEISGATIPSYFNFFTSGGGTLFPPCTRNEDLFNKKNIREL
                     SFLADDVWLNFLVVKNGIKTVKATRYKGTPLTIDDNPEESLVYLNTVYDNNNDKCIRN
                     MVEYYQINFTEDK"
     gene            31155..32579
                     /locus_tag="ACL3GT_000316"
     CDS             31155..32579
                     /locus_tag="ACL3GT_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HGR0516044.1"
                     /translation="MNVEKNLKRGIFYTAIGKYSNVVIQLLVTAILSRILSPVEYGIV
                     AVVNVFLLFFQMLADSGIGPAIVQNKELNKSDLISIFSLTIYSGIVLSCIFALLGYPM
                     GVLYGETIYVSLFPLLGLCVLFYTITIVPQAILMKTMNFKIVNFLTIFSNIASGLVGV
                     ILAVSHFGVYSLIFSNIVKAMVLFIALYSKAKINFYWKVSKSSIGKIFEFSKFQFLFN
                     FWNYFARNLDNLLIGRLISPSDLGYYDKAYQLSLYPNQILSQVVTPALHPIMSNFQDN
                     ISKIGEVYLQISRIFVIVGIPISAYLYFNAQYVVTFMFGDNWSQSVPVFQILAATIWL
                     QMANSPTGAFYQATNQTKLLFRIGLLTSFINILAIVIGVMLQSIQCVAYMLLISFSLS
                     LVINTLYLTKKVLNISAQKYIKPILINLTIISPYIVFNLFISDFVNDLILHLSVQFVI
                     LFLIWGIGMYISGEYRRVFAVIRK"
     gene            32592..33794
                     /locus_tag="ACL3GT_000317"
     CDS             32592..33794
                     /locus_tag="ACL3GT_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0516045.1"
                     /translation="MKILFVNMFYNEAGGAQKSTKFLAEQLVKEGHEVFAYSDDAIDS
                     DIDEVINRVKIFRRRTPLFSLHYIFSAKKNPAKHFFYKIFETYNVFAKRKFINIIEEV
                     QPDIVHFNTISGMSLSIVKEAKKRNIRTVWTLRDYWLEYPWGEKDISLIKLLNRIYRP
                     FVKKSLRHLDIVTAPSAFTLNNFINKGFINPSSQKCMVIENAVIFSKGKLENIIKQKQ
                     ETKRNPEKTNFLFVGSILEIKGVFNLVKAFKKLTSPEISLKIVGKGKDLEKLQKEIES
                     DPRIQYLGFQDTETLYKTYQNSDVLVVPSAWDEPFGRVVIEGNANGLPVITSDRGGLP
                     EIVQTVGGGEIFTDESGNTLYSLLKKFVEMENYNVYYQCILENIDIYSIEKQSEKFTN
                     LYLDKEIE"
     gene            33828..35060
                     /locus_tag="ACL3GT_000318"
     CDS             33828..35060
                     /locus_tag="ACL3GT_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGR0516046.1"
                     /translation="MKIAVAGTGYVGLSIAVLLAQHHEIKAVDIVAEKVELINQKKSP
                     IQDDYIEKYLVEKDLNLEATMDAKYAYEDAEFVVVAAPTNYDSKKNFFDTSAVEAVIQ
                     QVKKINPKAVIIIKSTIPVGFTESVQKKYQYKNILFSPEFLRESKALYDNLYPSRIIV
                     GTDLEDTYLKDKANIFASLLKEGAIKEDIDTLFMGVTEAEAVKLFANTYLALRVSYFN
                     ELDTYAEVKGLDAKAIIDGIGLDPRIGNHYNNPSFGYGGYCLPKDSKQLLANYFDVPQ
                     NMMTATVESNRTRKDFIAQRILEKAGVSETDSLDAFKNIQDIVIGIYRLTMKSNSDNF
                     RHSSIQGVMKRLKAKGVTVIIYEPTLKDGETFFGNKVVNNLDKFKEASNVIVANRFEP
                     SLEDVSNKVYSRDIFKRD"
     gene            35279..36129
                     /locus_tag="ACL3GT_000319"
                     /pseudo
     CDS             35279..36129
                     /locus_tag="ACL3GT_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            36080..36814
                     /locus_tag="ACL3GT_000320"
     CDS             36080..36814
                     /locus_tag="ACL3GT_000320"
                     /inference="COORDINATES: protein motif:HMM:NF013884.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGR0516047.1"
                     /translation="MQKVAGASVRVPTMIFNLLNIYKFPLGVSWYLYTLWSILIVYGL
                     LSVVFKNRKSLLLVSVFAYIFTLFIQTDIFIVQRTLVWGICFFLGSVLSEIHFDKINL
                     KKFLFFFVLFDFIYMFAWFLFYEVGSKKDYVSYINPGLWGIAFIVCVLVAFAIFPKME
                     KNFPKTFLYFTKYGKDSLGIYILHAPICSMIRILMLKVGINSVFLHVVVGIVLGWYLS
                     ILATYILKKIPFLNIVLLPQKYIKLK"
     gene            36992..38974
                     /locus_tag="ACL3GT_000321"
     CDS             36992..38974
                     /locus_tag="ACL3GT_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0516048.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGGIKDFSQVG
                     IKVLDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            39275..44578
                     /locus_tag="ACL3GT_000322"
     CDS             39275..44578
                     /locus_tag="ACL3GT_000322"
                     /EC_number="3.2.1.97"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033926 -
                     endo-alpha-N-acetylgalactosaminidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SpGH101 family
                     endo-alpha-N-acetylgalactosaminidase"
                     /protein_id="HGR0516049.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDERDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KQALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEITVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASVTVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HNPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNTNFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSNQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(44745..46904)
                     /gene="pbp1a"
                     /locus_tag="ACL3GT_000323"
     CDS             complement(44745..46904)
                     /gene="pbp1a"
                     /locus_tag="ACL3GT_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1A"
                     /protein_id="HGR0516050.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(46901..47497)
                     /gene="recU"
                     /locus_tag="ACL3GT_000324"
     CDS             complement(46901..47497)
                     /gene="recU"
                     /locus_tag="ACL3GT_000324"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HGR0516051.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            47563..48090
                     /locus_tag="ACL3GT_000325"
     CDS             47563..48090
                     /locus_tag="ACL3GT_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HGR0516052.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            48160..48489
                     /gene="gpsB"
                     /locus_tag="ACL3GT_000326"
     CDS             48160..48489
                     /gene="gpsB"
                     /locus_tag="ACL3GT_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HGR0516053.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            48510..48890
                     /gene="rnpB"
                     /locus_tag="ACL3GT_000327"
     ncRNA           48510..48890
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACL3GT_000327"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            48975..50132
                     /locus_tag="ACL3GT_000328"
     CDS             48975..50132
                     /locus_tag="ACL3GT_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HGR0516054.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREMRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QVAGVAGDITFKQMRVQDLCSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            50145..51539
                     /gene="mapZ"
                     /locus_tag="ACL3GT_000329"
     CDS             50145..51539
                     /gene="mapZ"
                     /locus_tag="ACL3GT_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HGR0516055.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLGKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            51615..53039
                     /gene="gndA"
                     /locus_tag="ACL3GT_000330"
     CDS             51615..53039
                     /gene="gndA"
                     /locus_tag="ACL3GT_000330"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HGR0516056.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPYLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            53051..53740
                     /locus_tag="ACL3GT_000331"
     CDS             53051..53740
                     /locus_tag="ACL3GT_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0516057.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGIGYTMQE"
     gene            53838..54860
                     /gene="cbpC"
                     /locus_tag="ACL3GT_000332"
     CDS             53838..54860
                     /gene="cbpC"
                     /locus_tag="ACL3GT_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HGR0516058.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGSTWYYLDPSNGDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            54878..55876
                     /gene="cbpJ"
                     /locus_tag="ACL3GT_000333"
     CDS             54878..55876
                     /gene="cbpJ"
                     /locus_tag="ACL3GT_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HGR0516059.1"
                     /translation="MKILKKTMQVGLTVFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDSTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(55994..57226)
                     /locus_tag="ACL3GT_000334"
     CDS             complement(55994..57226)
                     /locus_tag="ACL3GT_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0516060.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(57269..58144)
                     /locus_tag="ACL3GT_000335"
     CDS             complement(57269..58144)
                     /locus_tag="ACL3GT_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0516061.1"
                     /translation="MYPPELDSKILSIIKKAVTIRTTHTYEYQYSLLFGDAGYLWLLL
                     HLFSISKNQYYLQLANVTAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLK
                     IFIHNSIGEIYHYFLQRDTAKESILDYSFAHGYCGIAYALFAYSKVLEPSMFYNDLHT
                     FHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLCMYDCDGNKDIISKYQEFVFN
                     HHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILACSERDDHGLLMFQGDSGKAD
                     LFDFGIGSMGYIGVY"
     gene            58860..59084
                     /locus_tag="ACL3GT_000336"
                     /pseudo
     CDS             58860..59084
                     /locus_tag="ACL3GT_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            59206..60084
                     /gene="mvk"
                     /locus_tag="ACL3GT_000337"
     CDS             59206..60084
                     /gene="mvk"
                     /locus_tag="ACL3GT_000337"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HGR0516062.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITETCVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            60066..61019
                     /gene="mvaD"
                     /locus_tag="ACL3GT_000338"
     CDS             60066..61019
                     /gene="mvaD"
                     /locus_tag="ACL3GT_000338"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HGR0516063.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEYLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            61006..62013
                     /locus_tag="ACL3GT_000339"
     CDS             61006..62013
                     /locus_tag="ACL3GT_000339"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HGR0516064.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDILIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVSFEEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            61997..63007
                     /gene="fni"
                     /locus_tag="ACL3GT_000340"
     CDS             61997..63007
                     /gene="fni"
                     /locus_tag="ACL3GT_000340"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HGR0516065.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            63084..63782
                     /gene="liaF"
                     /locus_tag="ACL3GT_000341"
     CDS             63084..63782
                     /gene="liaF"
                     /locus_tag="ACL3GT_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HGR0516066.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            63779..64774
                     /locus_tag="ACL3GT_000342"
     CDS             63779..64774
                     /locus_tag="ACL3GT_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0516067.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            64788..65420
                     /locus_tag="ACL3GT_000343"
     CDS             64788..65420
                     /locus_tag="ACL3GT_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0516068.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF"
     gene            65496..66179
                     /locus_tag="ACL3GT_000344"
                     /pseudo
     CDS             65496..66179
                     /locus_tag="ACL3GT_000344"
                     /inference="COORDINATES: protein motif:HMM:NF020296.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            66329..66568
                     /locus_tag="ACL3GT_000345"
     CDS             66329..66568
                     /locus_tag="ACL3GT_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516069.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            66649..67470
                     /gene="cbpG"
                     /locus_tag="ACL3GT_000346"
     CDS             66649..67470
                     /gene="cbpG"
                     /locus_tag="ACL3GT_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HGR0516070.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHSYYRHDYGKEADDIYVLPAVSP
                     SQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            67489..68511
                     /gene="cbpF"
                     /locus_tag="ACL3GT_000347"
     CDS             67489..68511
                     /gene="cbpF"
                     /locus_tag="ACL3GT_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HGR0516071.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRQEIAFRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWV
                     YDDGDWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQHLGNKWYYLRSSGAMATGWYQDGSTWYYLDAENGDMKTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(68639..69979)
                     /locus_tag="ACL3GT_000348"
                     /pseudo
     CDS             complement(68639..69979)
                     /locus_tag="ACL3GT_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            70188..71957
                     /locus_tag="ACL3GT_000349"
     CDS             70188..71957
                     /locus_tag="ACL3GT_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HGR0516072.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGASPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            71981..73936
                     /locus_tag="ACL3GT_000350"
     CDS             71981..73936
                     /locus_tag="ACL3GT_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0516073.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEIMKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            73938..74375
                     /locus_tag="ACL3GT_000351"
     CDS             73938..74375
                     /locus_tag="ACL3GT_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0516074.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            74437..75573
                     /locus_tag="ACL3GT_000352"
     CDS             74437..75573
                     /locus_tag="ACL3GT_000352"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HGR0516075.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNDFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPTQSHEDSLFVMVEPFNEWVVETKRLKNPDLRLEDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
BASE COUNT        23525 a        12905 c        16543 g        23112 t
ORIGIN      
        1 taaaaatgga atattttgaa atttctgtct attaaaatgg ttaaaaagat aatgaaagcg
       61 ctaatatttt tttaaaaaaa ctattgacaa gataaaaata aaggattaca atggggaata
      121 taaagtaaac cggtaaacct aaacaagaaa ggagaaaaga tgaaaattgt acttgtaggg
      181 catggacatt ttgctacagg gatttatagt tctttacaat tgattgcagg caatcaagaa
      241 agtgtggagg cgattgactt tgtggaagga atgtcagcag atgaactcaa gcaaaaaatc
      301 ttacttgcaa tttcaaatga agaagaagtt ttaatcctaa gtgatctctt gggaggatcg
      361 ccattcaagg tttcttctac cataatggga gaaaatccag ccaaaacaat gaatgttctc
      421 tcgggtttga acttagccat gttaatggaa gcagtctttg ctagaatggc tcatagcttt
      481 gatgaggttg ttaataaatc agtagtggcg gcccagggcg gagtcgtaaa tggtaaagaa
      541 ttgttttcaa cggatgcaga ggaagaggaa gaagatttcg aatcgggtat ttaaagggta
      601 aaagaatgat aaaaaaggtt acgattgaaa aaataaaatc gcctgagcgc ttcttagaag
      661 taccacttct gacgaaagaa gaagtcggcc aggcaatcga taaggttatt cggcagttag
      721 aactcaacct tgactatttc aaggaagatt tccctacgcc agctaccttt gataatgtct
      781 atccaatcat ggataacacg gaatggacca atggtttctg gacaggagaa ctgtggttgg
      841 cttatgaata cagtcaacag gatgcattta aaaacatcgc tcataaaaat gttctttctt
      901 tcctggatcg tgtcaataag agagtagaat tggatcacca tgatctcggc ttcttgtaca
      961 caccgtcttg tatggctgaa tataagataa atggagatgg agaggctaga gaagcaacct
     1021 tgaaagctgc agataagttg attgaacgct atcaagaaaa aggtggtttt attcaagctt
     1081 ggggagactt gggcaagaaa gagcattacc gtttgattat cgactgcttg ctcaatatcc
     1141 aactcttatt ctttgcttat caagaaacag gcgatcaaaa atactacgat attgcagaaa
     1201 gtcatttcta tgcttcagct aataatgtaa tccgtgatga cgcttcgtcc ttccacacct
     1261 tctattttga tcctgagaca ggtcaaccct ttaaaggtgt aacgagacaa gggtatagtg
     1321 atgattcatg ctgggcacgt ggtcaatcat ggggagtcta tggtattcct ttgacttatc
     1381 gtcacttaaa agacgagtcc tgctttgact tgtttaaggg tgtgaccaat tatttcttga
     1441 atcgtctgcc aaaagatcat gtgtcctatt gggatttgat ttttaatgat ggtagtgatc
     1501 aatcacgaga ttcttcagca acagctatcg ccgtctgtgg gattcatgaa atgctaaaac
     1561 atctcccaga ggtggatgct gacaaagata tttataaaca tgctatgcat gccatgcttc
     1621 gttccttgat cgaacattat gcaaatgatc aatttacccc tggtgggaca agtctcctcc
     1681 acggtgtgta ctcatggcat tcaggtaaag gagtggatga aggcaatatc tggggtgact
     1741 actattacct agaagccctt atccgtttct acaaagactg gaacctatat tggtaggagg
     1801 agaaatatga caatgccaaa tattattatg acccgtatcg atgaacggtt gattcatgga
     1861 caaggacaac tttgggtaaa atacctaggt tgtaatacgg tcattgttgc caatgacgaa
     1921 gtaagcacgg acaagatgca acaaactctg atgaaaacag ttgtgccaga ctcagttgcc
     1981 atgcgtttct tccctttgca aaaggtgatt gatatcattc acaaggctaa tcctgctcaa
     2041 acgatcttta tcgttgtaaa ggatgtgaag gacgctttaa ccttggtaga aggtggtgtc
     2101 cctatcaaag aaatcaatat tgggaacatt cacaatgcta ctggtaaaga gcaagtgaca
     2161 cgctccatct tcctgggtga agaggacaag gcagccctca aggaattaag ccaaactcat
     2221 caagtaacat ttaatacgaa aacaactcca acaggaaatg atggagctgt tcaagtcaac
     2281 attatggact atatttaaaa gaggagatcg ttatgtcgat taatgtattt caagcgattt
     2341 taattggatt atggacagct ttctgtttta gtggaatgct attaggaatt tacaccaata
     2401 gatgtattgt tctgtcattt ggtgtcggaa ttattctagg tgatctgcct actgctcttg
     2461 caatgggagc tattggtgaa ttggcttata tgggattcgg tgttggtgct ggaggtactg
     2521 ttccaccaaa cccaatcgga cctggtatct ttggtacctt gatggctatc actagtgctg
     2581 gtaaagtcag tccagaagcg gctcttgccc tctctactcc gattgctgtg gcgattcaat
     2641 tcttacaaac tttcgcctac actgtacgtg ctggtgcgcc tgaaacggcg atgaagcact
     2701 tgaaaaacca taatttgaag aaattcaagt tcactctaaa tgcaacaatt tggttgtttg
     2761 cctttattgg atttaccttg ggttgcttgg gtgccctttc aatggatacc ttgttgaaac
     2821 tcgtagacta cattccaccg gtattgctta caggtttgac agttgctggt aaaatgctcc
     2881 cagctatcgg ttttgcgatg atcttgtcag tgatggctaa gaaagagttg attccctttg
     2941 tcttgttggg atatgtttgt gcagcttatc taaacatccc aacaattggt attgcaattg
     3001 taggtactat ctttgctttg attgaatttt ataacaagcc aaaaacagcg gatcatgtgg
     3061 tagaggagga agcacacgat gactggatct aacaaattaa caaaacgtga ttatcttaaa
     3121 acgtctttgc gggcattctt ttgtcaaaat ggatttaact atagtaacta tcaagggttg
     3181 ggatatgcca atgtgatgta tcctgctttg aaaaaacact atggagagaa tcaggaaggt
     3241 ttctaccaag ccttggaaga aaactgtgaa ttctataata ccaacccaca cttcctgcct
     3301 tttattacca gcttgcatct tgtaatgttg gaaaatggcc gtccggcaaa agaaacacgt
     3361 agcatcaaga tggccttgat gggaccatta gcaggtattg gggattctct ctctcaattc
     3421 tgtttagctc cattgttctc aaccatcgca gcttcgtttg ctcaagaagg cttggttgtc
     3481 ggtccaatct tgttcttcct tgcgatgaat acgattttaa cagcgattaa attgtcaact
     3541 ggtctgtatg gatacaaact aggaacgact gtgattgata aactaagcga gcagatggca
     3601 acgatttctc gtattgccaa tattattggt gtaaccgtaa ttgctggttt ggcagcgaca
     3661 tctgttaaga ttatggtacc gatcaccttt gctgcagggg aagttaaagc agacgctaaa
     3721 caaagtatcg taagtattca gggaatgctt gataaggttg ctccagctct tctaccagcc
     3781 ctatttacac ttttagttta ctacttgatc aaagaaaaga aatggacaac atataaactc
     3841 gttattttaa cagttatcat cggaattatc ggaagctggc ttaagattat agcttaatgg
     3901 atacaacatt gttttatgga atagtgattg tcttggcagt gagtcccctt ttactgtcaa
     3961 gctttcattc tattcgtcag caaaagttgc ttcgcaaaca gatggagcaa cgacaagagt
     4021 atttagcttc tttaacatct ggtgatgaag tgttgttatt gtctggaatt catggaaaaa
     4081 tcatttctat ccaagatgac ttggtctcct tgcagattgc aaaaggtgtg gtcatctatg
     4141 tagaaaagga aagtgtaatg ggaaagacaa aagaactgct ttttaagtag ttctttttct
     4201 ggtaatagat aatgaaagaa gaaagaagac aattttttga aagaatcgat ggaaaccaat
     4261 gtcgtgatta tatcttgtcc cactgttcaa aagactatga gaaagtcaag agttcccttg
     4321 aacgcttgat ggacaatcgt tttatgtttg atagtccttg ggatatggag ccttgttcaa
     4381 aaatccatca aatccagccg atggtatggg atcaagtatt tgaagatgat ccagaatggt
     4441 cttatatgct caatcgacaa gaatatctct tgcagtttat gatagggtat gtggtagaag
     4501 gagataagga ctatattcaa aagtgcaagt tctttctatt tgattggatt gagcaggtga
     4561 gagaattttc tcctcaatcc ttgatgacta gaaccttgga taccggtatt cgttccttta
     4621 cttggttgaa actactcttg ctcctcttga aatttgactt gctagaggag aaagaactag
     4681 agaaaatttt ggtcagtcta gaaaagcaga ttgactttat gaaaagccac tatcgcgcca
     4741 agtacaccct tagtaactgg ggaattttac aaacaattcc gatgcttgct atctatcatt
     4801 tctttgcaga taagatggac ctagaagaag cttaccattt tgcttcagag gagttgaaac
     4861 agcaaattga gacacagatt ttaggagatg gaagccagtt tgaacagtcg attctctatc
     4921 atgtagaggt ttataaagcc ttgctggatt tgtgtctctt gcttccagac ttgcaagata
     4981 gttaccaaga gttgctggaa aagatggcga cctatattca aatgatgaca ggcttagatg
     5041 gacgaacttt ggcttttggt gatagcgatt ctacagaaac gacagaaatg ttgagcctgt
     5101 ctgctgtggt tttgaacaag gaagaccttc ttaacggtct ggatgttaaa gtcgatttgc
     5161 ttagcctctt gttcctgggg cgagaaaagg tcaagcgact gcaggaattt gaaaagcgag
     5221 cttggcagcc taagttcatg agctttgaag actctggaca tgtctgcatt aaggatgaac
     5281 atcgttatct atttttcaaa aatggtccgc taggaagtgc ccatagccat agtgacgaga
     5341 atagtttttg cttacagtat caaggccaac ctattttcat agatgctggg cgttattctt
     5401 atcgggagat atatgaacgt tatctcttaa agagtgcttg gagtcattcg acctgcattg
     5461 tagatgggaa agctccggaa agaatcacgg gatcctggga atatgaatac tatcctcact
     5521 ccctgttttg tcaccataaa gaaagggagg gaatgcatta tattgaaggg gcttattggt
     5581 cagcagaacc tgatttgcct tatcttcaca ggagaaaaat cctcatgttg gtagaggatg
     5641 tctggctctt ggtagatgac atcaggtgtc aaggtcagca tgaggcgttg actcagttta
     5701 tccttgacaa ggatgtgacc tatcaagatg ggaaaatcaa tcagttgaga ctatggagtg
     5761 aagttgattt tgatttggaa gataccatca tttctcctaa atacaatgag cttgaaagaa
     5821 gtagcaaact caccaagcgc caattctttg agaatcagat gctggattat accatcattg
     5881 cgcatgagag ttttgaaatc atccgtcatt ctgtctacca gacagatgat cgtgaagtgg
     5941 aaaatgctct ggcttttgaa gtgaaaaatg acgaaacaga caagctgatt ctgttattaa
     6001 gcgaggatat ttgtgtaggt gaaaaattgt gcctcgttga cggaacaaaa atgcgtggaa
     6061 aatgtctagt atatgataaa ataaatgaga gaatgattcg cttgcagtgc tagaaatagg
     6121 cattttgaat agtgaatatg ttataataag tattagtagg aggtgtttta gattggagaa
     6181 gaaactgacc ataaaagaca ttgcggaaat ggctcagacc tcgaaaacaa ccgtgtcatt
     6241 ttacctaaac gggaaatatg aaaaaatgtc ccaagagaca cgtgaaaaga ttgaaaaagt
     6301 tattcatgaa acaaattaca aaccgagcat tgttgcgcgt agcttaaact ccaaacgaac
     6361 aaaattaatc ggtgttttga ttggtgatat taccaacagt ttctcaaacc aaattgttaa
     6421 gggaattgag gacatcgcca gccagaatgg ctaccaggta atgataggaa atagtaatta
     6481 cagccaagag agtgaggacc ggtatattga aagcatgctt ctcttgggag tagacggctt
     6541 tattattcag ccgacctcta atttccgaaa atattctcgt atcatcgatg agaaaaagaa
     6601 gaaaatggtc ttttttgata gtcagctcta tgaacaccgg actagctggg ttaaaaccaa
     6661 taactatgat gccgtttatg acatgaccca gtcctgtatc gaaaaaggtt atgaacattt
     6721 tctcttgatt acagcggata cgagtcgttt gagtactcgg attgagcggg caagtggttt
     6781 tgtggatgct ttaacagatg ctaatatgcg tcacgccagt ctaaccattg aagataagca
     6841 tacgaatttg gaacaaatta aggaattttt acaaaaagaa atcgatcccg atgaaaaaac
     6901 tctggtattt atccctaact gttgggccct acctctagtc tttaccgtta tcaaagagtt
     6961 gaattataac ttgccacaag ttgggttgat tggttttgac aatacggagt ggacttgctt
     7021 ttcttctcca agtgtttcga cgctggttca gccctccttt gaggaaggac aacaggctac
     7081 aaagattttg attgatcaga ttgaaggccg caatcaagaa gaaaggcaac aagtcttgga
     7141 ttgtagtgtg aattggaaag agtcgacttt ctaaaatgaa ggaaaatgac ttgcaatctc
     7201 tgttaagaaa taaaataatc ccacctagaa caagctaggt gggattattt gcctatgaaa
     7261 tgagaaatta tgggagcaag ctcctaaatc aactgttttt gatctacttc tttaactact
     7321 tgataaaagt tatagaagta ggccaaactt gaaatgatgg ttacgactag gaatattgaa
     7381 aatttccatt ggacagggtt ggttaaaagt tgtggaaagg atatgaggag aaagaagagg
     7441 gctgcgttga ggacaggtat ccgttttgat tgtattttct caagtccttt attgagcgca
     7501 ggaagaaaga ggagtaggag tagtaaaact gtatgagaaa cagctcctga aataagggca
     7561 aagaaaagga aaatactgat aaaaacatga atgatcagta gtctagctag tgatttcata
     7621 aggtacctcc taatcctggt cttttttagc tcttgcaata cgaagtgagt cgacaatatg
     7681 tatcatcact ccgaaaaaga aagctcccag tatagtttta aaaatatgtt ttgtatttag
     7741 aagagaactg ataaaatttg gattttcact tgttagggta tcaatgagtg gaattataaa
     7801 aaatatcact gttccataaa tcgaacctgc tttcagacca ggataacgta actgtttctt
     7861 ttcttttttc atgagtttgc tcctttttta aaaatcttcc tcccaaaaga gactgttgag
     7921 gtcagtttgg aggctgcggg cgagattgag acagagttcc aaggttggat tgtacttgtc
     7981 gttttcaatc atattgatag tctgtctcga gacaccgata tccttggcga gttcgagctg
     8041 ggaaataccc aattccttgc gaaattcttt cacacgattc atctggtctc ctttctgatt
     8101 tatgtcgtat atatttgact atattatagt cttttaaaca taaagtgtca agtatttttg
     8161 acatattttt tgaagaaata gtagtctcct tgtcctattt gtctgacaag tgcaagctgg
     8221 tcggatttgt ggtaaaatag ataagatatg acaaaagaat ttcatcatgt aacggtctta
     8281 ctccacgaaa cgattgatat gcttgacgta aagcctgaag gtatctacgt tgatgcgact
     8341 ttgggcggag caggacatag cgagtattta ttaagtaaat taagtgaaaa aggccatctc
     8401 tatgcctttg accaggatca gaatgccatt gacaatgcgc aaaaacgctt ggcaccttac
     8461 attgagaagg gaatggtgac ctttatcaag gataacttcc gtcatttaca ggcacgtttg
     8521 cgcgaagctg gtgttcagga aattgatgga atttgttatg acttgggagt gtctagtcct
     8581 caattggacc agcgtgagcg tggtttttct tataaaaagg atgcgccact ggacatgcgg
     8641 atgaatcagg atgctagtct gacagcctat gaagtggtta atcattatga ctatcatgat
     8701 ttggttcgta ttttcttcaa atacggtgag gataaattct ctaaacagat tgcgcgtaag
     8761 attgagcaag cgcgtgaagt gaagccgatt gagacaacga ctgagttagc agagattatc
     8821 aagttggtca aacctgccaa ggaactcaag aagaagggtc atcctgctaa gcagattttc
     8881 caggctattc gaattgaagt caatgatgaa ctgggagcgg cagatgagtc catccagcag
     8941 gctatggata tgttggctct ggatggtaga atttcagtga ttacctttca ttccttagaa
     9001 gaccgcttga ccaagcaatt gttcaaggaa gcttcaacag ttgaagttcc aaaaggcttg
     9061 cctttcatcc cagatgatct caagcccaag atggaattgg tgtcccgtaa gccaatcttg
     9121 ccaagtgcgg aagagttaga agccaataac cgctcgcact cagccaagtt gcgcgtggtc
     9181 agaaaaattc acaagtaaga gggaaaaaga tggcagaaaa aatggaaaaa acaggtcaaa
     9241 tactacagat gcaacttaaa cggttttcgc gtgtggaaaa agctttttac ttttccattg
     9301 ctgtaaccac tcttattgta gccattagta ttatttttat gcagaccaag ctcttgcaag
     9361 tgcagaatga tttgacaaaa atcaatgcgc agatagagga aaagaaaacc gaattggacg
     9421 atgccaagca agaggtcaat gaactattac gtgcagaacg tttgaaagaa attgccaatt
     9481 cacacgattt gcaattaaac aatgaaaata ttagaatagc ggagtaagat atgaagtgga
     9541 caaaaagagt aatccgttat gcgaccaaaa atcggaaatc gccggctgaa aacagacgca
     9601 gagttggaaa aagtctgagt ttattatctg tctttgtttt tgccattttt ttagtcaatt
     9661 ttgcggtcat tattgggaca ggcactcgct ttggaacaga tttagcgaag gaagctaaga
     9721 aggttcatca aaccacccgt acagttcctg ccaaacgtgg gactatttat gaccgaaatg
     9781 gagtcccgat tgctgaggat gcaacctctt ataatgtcta tgcggtcatt gatgagaact
     9841 ataagtcagc aacgggtaag attctttacg tagaaaaaac acaatttaac aaggttgcag
     9901 aggtctttca taagtatctg gacatggaag aatcctatgt aagagagcaa ctctcgcaac
     9961 ctaatctcaa gcaagtttcc tttggagcaa agggaaatgg gattacctat gccaatatga
    10021 tgtctatcaa aaaagaattg gaagctgcag aggtcaaggg gattgatttt acaaccagtc
    10081 ccaatcgtag ttacccaaac ggacaatttg cttctagttt tatcggccta gctcagctcc
    10141 atgaaaatga agatggaagc aagagcttgc tgggaacctc tggaatggag agttccttga
    10201 acagtattct tgcagggaca gacggcatta ttacctatga aaaggatcgt ctgggtaata
    10261 ttgtacccgg aacagaacaa gtttcccaac gaacgatgga cggtaaggat gtttatacaa
    10321 ccatttccag ccccctccag tcctttatgg aaacccagat ggatgctttt caagagaagg
    10381 taaaaggaaa gtacatgaca gcgactttgg tcagtgctaa aacaggggaa attctggcaa
    10441 caacgcaacg accgaccttt gatgcagata caaaagaagg cattacagag gactttgttt
    10501 ggcgtgatat cctttaccaa agtaactatg agccaggttc cactatgaaa gtgatgatgt
    10561 tggctgctgc tattgataat aatacctttc caggaggaga agtctttaat agtagtgagt
    10621 taaaaattgc agatgccacg attcgagatt gggacgttaa tgaaggattg actggtggca
    10681 gaatgatgac tttttctcaa ggttttgcac actcaagtaa cgttgggatg accctccttg
    10741 agcaaaagat gggagatgct acctggcttg attatcttaa tcgttttaaa tttggtgttc
    10801 cgacccgttt cggtttgacg gatgagtatg ctggtcagct tcctgcggat aatattgtca
    10861 acattgcgca aagctcattt ggacaaggga tttcagtgac ccagacgcaa atgattcgtg
    10921 cctttacagc tattgctaat gacggtgtca tgctggagcc taaatttatt agtgccattt
    10981 atgatccaaa tgatcaaact gctcggaaat ctcaaaaaga aattgtggga aatcctgttt
    11041 ctaaagatgc agctagtcta actcggacta acatggtttt ggtagggacg gatccggttt
    11101 atggaaccat gtataaccac agcacaggca agccaactgt aactgttcct gggcaaaatg
    11161 tagccctcaa gtctggtacg gctcagattg ctgacgagaa aaatggtggt tatctagtcg
    11221 gggtaaccga ctatattttc tcggctgtat cgatgagtcc ggctgaaaat cctgatttta
    11281 tcttgtatgt gacggtccaa caacctgaac attattcagg tattcagttg ggagaatttg
    11341 ccaatcctat cttggagcgg gcttcagcta tgaaagactc tctcaatctt caaacaacag
    11401 ctaaagcttt ggagcaagta agtcaacaaa gtccttatcc tatgcctagt gtcaaggata
    11461 tttcacctgg tgatttagca gaagaattgc gtcgcaatct tgtacaaccc atcgttgtgg
    11521 gaacaggaac gaagattaaa aacagttctg ctgaagaagg gaagaatctt gccccgaacc
    11581 agcaagtcct tatcttatct gataaagtag aggaagttcc ggatatgtat ggttggacaa
    11641 aggagactgc tgagaccctt gctaagtggc tcaatataga acttgaattt caaggttcgg
    11701 gctctactgt gcagaagcaa gatgttcgtg ctaacacagc tatcaaggac attaaaaaaa
    11761 ttacattaac tttaggagac taatatgttt atttccctca gtgctggaat tgtgacattt
    11821 ttactaactt tagtaggaat tccggccttt atccaatttt atagaaaggc gcaaattaca
    11881 ggccagcaga tgcatgagga tgtcaaacag catcaggcaa aagctgggac tcctacaatg
    11941 ggaggtttgg ttttcttgat tacttctgtt ttggttgctt tctttttcgc cctatttagt
    12001 agccaattca gcaataatgt gggaatgatt ttgttcatct tggtcttgta tggcttggtc
    12061 ggatttttag atgactttct caaggtcttt cgtaaaatca atgaggggct taatcctaag
    12121 caaaaattag ctcttcagct tctaggtgga gttatcttct atcttttcta tgagcgcggt
    12181 ggcgatatgc tttctgtctt tggttatcaa gtgcatctag ggattttcta tattgtcttc
    12241 gctcttttct ggctagtcgg tttttcaaac gcagtaaact tgacagacgg tgttgacggt
    12301 ttagctagta tttccgttgt gattagtttg tctgcctatg gagttattgc ctatgtgcaa
    12361 ggtcagatgg atattcttct agtgattctt gccatgattg gtggtttgct cggtttcttc
    12421 atctttaacc ataagcctgc caaggtcttt atgggtgatg tgggaagttt ggccctaggt
    12481 gggatgctgg cagctatctc tatggctctc caccaagaat ggactctctt gattatcgga
    12541 attgtatatg tttttgaaac aacttctgtt atgatgcaag tcagttattt caaactgaca
    12601 ggtggtaaac gtattttccg tatgacgcct gtacatcacc attttgagct tgggggattg
    12661 tctggtaaag gaaatccttg gagcgagtgg aaggttgact tcttcttttg gggagtggga
    12721 cttctagcaa gtctcctgac cctcgcaatt ttatatttga tgtaagaatg gcaccctgat
    12781 gtttcagggt gtttttgtgt ttaaatacac aatgaaaatc aaagaacaaa ctagaaagct
    12841 aactttaggc tgctcaaaat atagtagatt gaaactagaa tagtacacat ctacttctaa
    12901 aatattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgttctt atttcatttt
    12961 aatatacagt tttgaggttg tagataagga gaagctgatg tggtttgaag aggttttcga
    13021 agagtgtaaa aaaatattgg tcagttaaag tcaaaactct tgaccttttc tgactaatgt
    13081 agtatattat gaacgtaagg taaatgaaag ccttactaga acacttattt aaagtaaaat
    13141 agaaagaggt gggtctatgt ttcatctaga aatcttcaga agtaaagata gtctactcct
    13201 gcttgaaaaa gaaaaaccag aaatagtacg tagggtagcg atctagctag tctaaatttt
    13261 ttaaaacaat ggtcaaagat agtcaatatc agtaatcata actaagtaaa caaaaagagg
    13321 taaagaatat gaataacaac tttaataatt ttaataacat ggatgattta tttaaccaat
    13381 tgatgggtgg tatgcgagga tacagttctg aaaatcgccg ttacttaatt aatggacgcg
    13441 aagtcacacc tgaggaattt gctcactatc gtacgactgg tcaattacca ggaaatgcag
    13501 aaactgatgt gcaaatgcca caacaggcat caggtatgaa acaagacggt gtccttgcaa
    13561 aactaggtcg aaacttgaca gcagaagcgc gtgagggcaa gttggatcct gttatcggac
    13621 gaaacaagga aattcaagaa acatctgaaa tcctctcacg ccgcaccaag aacaatcctg
    13681 ttttggtcgg agatgcaggt gttggtaaga cagcagttgt cgaaggtcta gcgcaagcca
    13741 ttgtgaacgg agatgttcct gctgctatca agaacaagga aattatttct attgatatct
    13801 caggtcttga ggctggtact caataccgtg gtagctttga agaaaatgtc caaaacttag
    13861 tcaatgaagt gaaagaagca gggaatatta tcctcttctt tgatgaaatt caccaaattc
    13921 ttggtgctgg tagcactggt ggagacagtg gttctaaagg gcttgcggat attctcaagc
    13981 cagctctctc tcgtggagaa ttgacagtga ttggggcaac aactcaagac gaataccgta
    14041 acaccatctt gaagaatgct gctcttgctc gtcgtttcaa cgaagtgaag gtcaatgctc
    14101 cttcagcaga gaatactttt aaaattcttc aaggcattcg tgacctctat caacaacacc
    14161 acaatgtcat cttgccagac gaagtcttga aagcagcggt ggattattct gttcaataca
    14221 ttcctcaacg tagcttgcca gataaggcta ttgaccttgt cgatgtaacg gctgctcact
    14281 tggcggctca acatccagta acagatgtgc atgctgttga acgagaaatc gaaacggaaa
    14341 aagacaagca agaaaaagca gttgaagcag aagattttga agcagctcta aactataaaa
    14401 cacgcattgc agaattggaa aagaaaatcg aaaaccacac agaagatatg aaagtgactg
    14461 caagtgtcaa cgatgtggct gaatctgtgg aacgaatgac aggtatccca gtatcgcaaa
    14521 tgggagcttc agatatcgaa cgtttgaaag atatggctca tcgcttgcaa gacaaggtga
    14581 ttggtcaaga taaggccgta gaagctgtag ctcgtgctat ccgtcgtaac cgtgctggtt
    14641 ttgatgaagg aaatcgccca atcggcagct tcctctttgt agggtctact ggggttggta
    14701 agacggagct tgctaagcaa ttggcactcg atatgtttgg aacccaggat gcgattatcc
    14761 gtttggatat gtctgaatac agtgaccgca cagctgtttc taagctaatt ggtacaacag
    14821 caggctatgt gggttatgat gacaatagca ataccttaac agaacgtgtt cgtcgcaatc
    14881 catactctat cattctcttg gatgaaattg aaaaggctga tcctcaagtt attacccttc
    14941 tcctccaagt tctagatgat ggtcgtttga cagatggtca aggaaataca gtaaacttca
    15001 agaacactgt cattattgcg acctcaaatg ctggatttgg ctatgaagcc aacttgacag
    15061 aagatgcgga taaaccagaa ttgatggacc gtttgaaacc cttcttccgt ccagaattcc
    15121 tcaaccgctt taatgcagtc atcgagtttt cacacttgac taaggaagac ctttctaaga
    15181 ttgtagattt gatgttggct gaagttaacc aaaccttggc taagaaagac attgacttgg
    15241 tagtcagtca agcggctaaa gattatatca cagaagaagg ttacgacgaa gtcatggggg
    15301 ttcgtcctct ccgtcgcgtg gttgaacaag aaattcgtga taaggtgaca gacttccact
    15361 tggatcattt agatgctaaa catctggaag cagatatgga agatggcgtt ttggttattc
    15421 gtgagaaagc ctaagacaga attttgagaa taaaaaagaa ggagccagct gaaaaaaact
    15481 ggttcctttt gaggtacgac gggcatgtcg tgtagtagag atgtactatt ctagtttcaa
    15541 tctactatag tagctcagaa atcggtactt aaacgtgcta tatcaaaacc agtccttgaa
    15601 aaacgtggac tggtttcgtg tttggattat tactttgaac gacatgcgtt aaaagttagt
    15661 tgaaccgccg tatgccgaac ggtacgtacg gtggtgtgag aggggctaga gattatcccc
    15721 tactcgattt taaatcacat gacgttcaaa ggcatcatct gaaatccctt gttccaagat
    15781 gagttttgcc cattctttag cagagaagag gctgtggtcc ttgtagtttc cgcaagattc
    15841 gatggttgtc cctgggacat cttcccaagt agtagtttca gcgatttcct tgagcgaatc
    15901 cttgataaca gctgcgattt tagcactggt gtgacgtccc cacataatca tgtggaagcc
    15961 tgtgcggcaa ccaaatggcg aacagtcaat catgccgtca atgcgggtac ggatgagttt
    16021 ggctaagagg tgctcgatag tgtgaaggcc ggcggtaggg atagagtctt cgtttggttg
    16081 caccaagcga atatcataat tggagatgat gtctcctttt ggtcctgttt cttccccaat
    16141 caagcgaaca tagggtgctt tgacaatggt gtggtcaagt tcaaaacttt cgacaataac
    16201 ttcttttgac atggtaaatc ctttcagttt tcttctctca ttatatcata aaggttgctc
    16261 ctgagacaga gagaaaacct ctccgaggct ggagaggttg aaatctttac ttacgatata
    16321 agcggtcgta ttggtagtat gggtcaaagg ttacgttgat acccagttta cgaaggacat
    16381 tcttgtcttc atcagtcaag atgatggttg agtgggcttc gcttcctttg aggttgccga
    16441 gttcttccat agcgcgggta gcatcaggat tttctgtagc tgtgatagca agtgcaatca
    16501 ggatttcatt tgaatgaagg cgtggattgc ggctaccgag atgatcgatt ttaagacctt
    16561 ggattggctt aacaacttcc ggctcgatta attttacttc tttagcgatg tcagctgatt
    16621 ttttgatggc gttgatcaag gcagcggctg tagggccaaa gagttctgag ttcttaccag
    16681 tgacgatttc cccatttggc aattcaaagg ctagggctgg tccaccagtt tcttctgctt
    16741 tttggcgcgc aacgacagca accttacggt ctgcaggtgt gataccgagg tcgttcatga
    16801 gcaactcaat tttcttgacg gcagcttcgc caactttttc agctttgaag tcaagaactg
    16861 tttgatagta acggcggatg atttcttgtt tagaagcttc gacagcggcc tcgtcatctg
    16921 taatagcgaa accaaccatg ttgacaccca tatctgtcgg tgaagcgtat ggtgattttc
    16981 cgagaatacg ttccaacatg cgtttgagca ctgggaagat ttcgatatca cggttgtagt
    17041 tgacagtggt ttctccatag gtttggagat ggaaggggtc aatcatgttg acatcatcaa
    17101 ggtcagctgt ggcagcttca taagccaagt taactggatg atgaagggga agattccaaa
    17161 cagggaaggt ttcaaattta gcgtagccag atttgatgcc attgatttgg tcgtggtaca
    17221 tattggacat acacgttgcc aattttccag aaccaggtcc aggagcggtt acgacaatca
    17281 agttgcgact ggttttgatg tagtcgtttt tgcccatgcc ttctggggaa atgatgtgat
    17341 ccatatccgt cggatatcct ttgattggat aatgaagata tgaatcaatt ccgtttttct
    17401 caagttggtt gcggaaggca tctgcagcgg gttggccagc gtattgtgta atgacaacgg
    17461 aaccaacaaa aatccccaat tcattgaatt tgtcaatcaa acgaagaact tcttggtcat
    17521 aagaaatgcc taagtcgcca cgtgctttgg aatgttcaat gttgctagca ttaatggcaa
    17581 tcacaacctc aacctgctct ttcaattctt gcaagagctt gattttgttg tcaggttcat
    17641 aaccaggaag gacacgagca gcgtggaaat cttctaacat tttaccgcca aactctaagt
    17701 agagcttgcc gtcaaattgg ttaatacgct ccaaaatatg gtcgcgttgt aaattcaaat
    17761 attgttcaga actaaaagct tgttttttca tttttttacc tctggactct attataataa
    17821 aaaattggaa gttaggaaac tacggagcta aaaaagaaat taaaaagatt aagcaaacgc
    17881 ttgcacaaaa ttttaaaaag tgctatcata gactatagat tattaaaata atgaggtaaa
    17941 cagatgcaag aaaaatggtg gcataatgcc gtagtctatc aagtctatcc aaagagtttt
    18001 atggatagta atggagatgg agttggtgat ttgccaggta ttaccagtaa gttggactat
    18061 ctagccaagc taggaatcac agcaatttgg ctttctcccg tttatgacag ccctatggat
    18121 gataatggtt acgatattgc tgattatcaa gcgattgcaa cgatttttgg aaccatggag
    18181 gatatggatc aactgattgc agaagctaag aagcgtgata tccgtatcat catggacttg
    18241 gtggtcaatc atacctcgga tgagcatgcc tggtttgtag aggcctgtga aaatcctaat
    18301 agccctgagc gagactacta tatctggcgc gatgaaccca atgacctaga ttctatcttt
    18361 agtgggtctg cttgggaata cgatgaaaag tcaggtcaat actatctcca ctttttcagc
    18421 aagaaacagc cggatctcaa ctgggaaaat gaaaaacttc gccagaaaat ttatgagatg
    18481 atgaacttct ggattgataa aggtattggt ggtttccgta tggatgttat tgacatgatt
    18541 ggcaaaattc ctgacgagaa ggtagtcaat aatggtccta tgctccatcc ctatctcaag
    18601 gaaatgaatc aggcgacctt tggagataag gatctcttga cagtagggga gacttgggga
    18661 gcaacgccag agattgccaa gctctactct gatccaaagg ggcaagaatt gtctatggtc
    18721 ttccagtttg aacatatcgg tcttcagtat caggaaggtc agcctaaatg gcactatcaa
    18781 aaagagctga atatcgctaa gttaaaagaa atcttcaaca aatggcagac agagttagga
    18841 gttgaggacg gctggaattc cctcttctgg aacaaccatg acctccctcg tattgtctca
    18901 atatggggaa atgaccaaga ataccgcgaa aaatctgcca aagcctttgc aatcttgctt
    18961 catcttatga gaggaactcc ttatatctac caaggtgagg agattgggat gaccaactat
    19021 ccgtttgaaa cactagatca agtagaagat attgaatctc tcaactatgc gcgtgaggct
    19081 cttgaaaaag gtgttccgat tgaagaaatc atggacagta tccgtgttat tggacgtgac
    19141 aatgcccgta cccctatgca atgggacgag agcaaaaacg ctggtttctc aacaggtcaa
    19201 ccttggttgg cggttaatcc aaattacgag atgatcaacg tccaagaagc gctggcaaat
    19261 ccagattcta ttttctatac ctatcagaaa ctggtccaaa ttcgcaagga gaatagctgg
    19321 ctagttcgag ctgactttga attgcttgat acggctgata aggtctttgc ttatatacgt
    19381 aaggatggcg accgtcgctt cctagttgtg gctaacttgt ccaatgaaga gcaagacttg
    19441 acagtagaag gaaaagtcaa atctgtcttg attgaaaaca ccctagctca agaagtcttt
    19501 gaaaaacaaa tcttagttcc atgggatgct ttctgtgtgg aaatgactga ctagaatgag
    19561 caaacctcaa gtttttgaag cttgaggttt tttactatag tggattgaaa ctagaatagt
    19621 gcacctctgc ttctaaaaca ttgttagaaa tcgatttgac tgtcccgatc gatttgtcct
    19681 attcttattt cattttgcta tacttgtagt tgaggagaat taagctcctc actagtaaac
    19741 tcttcataat cctttttatt tttatgaaga tattgtttga aagatgtgag tttccacgga
    19801 tgggtttgtg gagggatata cttgcgtctt tctttttttg ttctggttct tgttcaaagt
    19861 ttttcgaata gagttcatga tttagtagct cctttgtgtg atagattttg tcagcgatat
    19921 tgaggtagat gtctccgtca aatgctttta taactaatgc tttcgtcttt ctgatgaaat
    19981 agacttcttt tccttgttcg gtagggatat agtaacgatt ttggaatcgg atatggtgtc
    20041 cactatcgac gactctctcc gccagtctag ccagaatgag attcctttca gaggggttag
    20101 gaacctcctc gaagacagag agttttgtct tgtttccaaa ctgttcatta aaggtttgaa
    20161 tgtaggaaag caggaaggta ttggcttctt ccaaggtatg aatattgttt tgttccagtt
    20221 cgataggcag gcgagattgt agtgtctgat tgagtctttc gactctccct ttagcttgag
    20281 ggatagaggt tgtctcaagg agaatcccta gttggtgaca ggcgtatcca aactgtgtat
    20341 gggtatcgtc ctccattttc ttagagttgg aggcttgata ggtaaagacc gttctcttat
    20401 ctgttttaat ttgaagggga atgccgtgat tggctaagat ttgttcgagg acatgatagt
    20461 aagcattcaa gttctcttgt ttatcaaaat aagcgcctag gatattgcca gaagcatcat
    20521 caatggctaa gtgtaagtta gatgtttggg ctccaaacta ggcatgaggg ctggcatcca
    20581 tttgaatgag ttcaccagca aatttctttc tgggtctact aggatgtact tttttagggt
    20641 cttcaaggaa gttttcagcc gtcggtaaga ttggattgtc taggggttga ttcaggttca
    20701 gtttagcttg ttttcttact ctcttctttg tctttctatg ggacttaggc gacaggatat
    20761 ttttcttata gagtattttt ctaacagtag tatcagagag ctgaattcct tcttcttcag
    20821 ctagcaattc acagaaatga aggacatttg gtttatatgt ttcataggag aggtattttt
    20881 ttaggagacg ttctttgatt tcatcaggga ttgcatgttt tggttttcga tttctgtttc
    20941 cgtgtctgaa ggcttctttt cctttcagtt gataggctag tagcagacga ttgatttgtc
    21001 tttcagaaag attgagctcg acacaggctc gtttctttgt tttctttcct tgggctatag
    21061 cttttatcac aagatatttt ttcgtttcat tcatattcag ttggatcctt ttcatatgac
    21121 tattctacca aatgggacat tttcacgttc gatttactaa agacattatc acattcgaat
    21181 tacacaagat gcagatagtg aaaataaagg tgtagacatt accgtaaaaa agtgatataa
    21241 ttgtatgatg ttcaatgtat aggtgttaat catgagtaga cgttttaaaa aatcaggttc
    21301 acagaaagtg aagcgaagtg ttaatatcgt tttgctgact atttatttat tgttagtttg
    21361 ttttttattg ttcttaatct ttaagtacaa tatccttgct tttagatatc ttaatctagt
    21421 ggtaactgcg ttagtcctac tagttgcctt agtagggcta ctcttgatta tctataaaaa
    21481 agctgaaaag tttactattt ttctgttggt gttctctatc cttgtcagct ctgtgtcgct
    21541 ttttgcagta cagcagtttg ttggactgac caatcgttta aatgcgactt cgaattactc
    21601 agaatattca atcagtgtcg ctgttttagc agatagtgag atcgaaaatg ttacgcaact
    21661 gacgagtgtg acagcaccga ctgggactga taatgaaaat attcaaaaac tactagctga
    21721 tatcaagtca agtcagaata ccgatttgac ggtcaaccag agttcgtctt acttggcagc
    21781 ttacaagagt ttgattgcag gggagactaa ggccattgtc ctaaatagtg tctttgaaaa
    21841 tatcatcgag tcagagtatc cagactacgc atcgaagata aaaaagattt ataccaaggg
    21901 attcactaaa aaagtagaag ctcctaagac gtctaagaat cagtctttca atatctatgt
    21961 tagtggaatt gacacctatg gtcctattag ttcggtgtcg cgatcagatg tcaatatcct
    22021 gatgactgtc aatcgagata ccaagaaaat cctcttgacc acaacgccac gtgatgccta
    22081 tgtaccaatc gcagatggtg gaaataatca aaaagataaa ttaacccatg cgggcattta
    22141 tggagttgat tcgtccattc ataccctaga gaacctttat ggtgtagata ttaattatta
    22201 tgttcgtttg aattttacct catttttgaa attgattgac ttattgggag gggtagatgt
    22261 tcataatgat caagagtttt cagctctaca taggaagttc cttttcccag tagggaatgt
    22321 ccatctagac tctgagcagg ctctaggttt tgtacgtgaa cgctactcac tagccgatgg
    22381 agaccgtgac cgtggtcgca accaacaaaa ggtgattgtg gctattcttc aaaaattaac
    22441 gtcaaccgaa gcactgaaaa attatagtac gatcattaat agcttgcaag attctatcca
    22501 aacaaatatg ccacttgaga ctatgataaa tttggtcaat gctcagttag aaagtggtgg
    22561 aacttacaaa gtgaattctc aagatttaaa agggacagat cggatggatc ttccttctta
    22621 tgcaatgcct gacagtaacc tctatgtgat ggaaatagat gatagtagtt tagctgtagt
    22681 taaagcagct atacaggatg tgatggaggg tagatgaaat gatagacatc cattcgcata
    22741 tcgtttttga tgtagatgac ggtcccaagt caatagagga aagcaaggca cttttaagag
    22801 aagcttataa tcaaggagtt cgaatgattg tgtctacttc gcatcgtcga aaagggatgt
    22861 ttgaaactcc ggaagagaag atagcagaaa actttcttca ggttcgggaa attgcaaaag
    22921 aagtagcaga tgatttagtc atagcttatg gcgcagagat atactatact ctggatgctc
    22981 tagaaaagct agaaaaaaaa gaaattccta cccttaatga tagtcgttat gctttgattg
    23041 agtttagcat gcatacttcc tatcgtgaga ttcatgcggg attgagcaat attttgatgt
    23101 tgggaatcac gccagtaatt gctcatattg aacgttatga tgccttagag aataacgaaa
    23161 aacgtgttcg tgaactgatt gatatggggt gctatactca gataaatagt tatcatgttt
    23221 taaaacctaa gttctttggt gaaaaatata aattcatgaa aaagagagct cggtattttt
    23281 tggaacgtga tttagttcat gtagttgcaa gtgacatgca caatttagac agtagacctc
    23341 catatatgca acaggcatat gatatcattg ctaagaaata tggagcgaaa aaagcgaaag
    23401 aattttttgt agataatccc agaaaaatta taatggatca attaatttag gagaaaatat
    23461 gaaggaacaa aacactttgg aaatcgatgt attgcaacta ttcagggctt tatggaaaag
    23521 aaagttggtc attttattag tggcaattat aacttcttca gttgcttttg cctacagtac
    23581 ttttgttatc aaacctgagt ttactagtac gactcggatt tatgtagtta accgtaatca
    23641 ggaagagaag tctggtttaa ccaatcaaga cttgcaggca ggatcatact tggttaaaga
    23701 ctatcgtgaa attatcctat cgcaggatgt tttggaggaa gttatttctg atttgaaact
    23761 agatttgacg ccaaaaggtt tggctaataa aattaaagta acagtaccag ttgatacccg
    23821 tattgtctct gtctcagtta atgatcgagt tcctgaagag gcaagccgta tcgctaactc
    23881 tttgagagaa gtagctgctc aaaaaattat cagtattact cgtgtttctg atgtgacaac
    23941 actggaggag gcaagaccgg cgatatcacc atcttcgcca aatattaaac gcaatacact
    24001 aattggtttt ttggcagggg ggattggaac tagtgttata gttcttcttc ttgaactttt
    24061 ggacactcat gtgaaacgtc cggaagatat cgaagataca ctgcagatga cacttttggg
    24121 agttgtacca aacttgagta agttgaaata ggagagagga atgccgacat tagaaatagc
    24181 acaaaaaaaa ctggagttca ttaagaaggc agaagaatat tacaatgcct tgtgtacaaa
    24241 tatacagttg agcggagata aactaaaagt aatttccgtt acttctgtta accctgggga
    24301 aggaaaaaca actacttccg taaatatagc aaggtcgttt gcgcgtacag gctataaaac
    24361 tcttttgatc gatggcgata ctcgaaattc agttatatca ggagttttta aatcgcgtga
    24421 aaaaattaca gggctaacag aatttttatc tgggacagct gatttatctc acggtttatg
    24481 tgatacaaat attgaaaatt tatttgtaat tcaatcggga tctgtatcac caaaccctac
    24541 agccttgtta caaagtaaaa attttaatga tatgattgaa acattgcgta aatattttga
    24601 ttatatcatt gttgatacag cacctattgg aattgttatt gatgcggcaa ttatcactca
    24661 aaagtgtgat gcgtccatct tggtaacagc aataggtgag gtgaataaac gtgatgtcca
    24721 aaaagcgaaa caacaattag aacaaacaga gaaactgttc ctaggagttg ttttaaataa
    24781 attggatatc tcggttgata agtatggagt ttacggttcc tatggaaatt atggtaaaaa
    24841 ataacttagg aaagatttta tggatgaaaa aggattgaaa atttttctag cagtaataca
    24901 gagtattatt gtcattttat tggtttattt tcttagcttt gttagagaga cagaacttga
    24961 acgttcttcg atggttatac tataccttct ccactttttt gtattctatt ttagttccta
    25021 tggtaacaat ttttttaaaa gagggtacct agttgagttt aatagtacta taagatatat
    25081 ttttttcttt gcaatagcta taagtgtatt aaactttttt atagcggaac ggtttagtat
    25141 ctctagaaga ggaatggtat acttcttaac tttagaagga atatccttat acttgttaaa
    25201 tttcttagta aagaaatatt ggaagcatgt gttttttaat ctaaaaaata gcaagaaaat
    25261 tttactgtta acagtaacga aaaatatgga aaaagttctt gataaattgc tagaatctga
    25321 tgaactttca tggaaattgg tagcagtaag tgttttggat aaatctgatt ttcaacatga
    25381 taaaatacct gtaattgaaa aggaaaaaat tattgaattt gcaacgcatg aagttgtgga
    25441 tgaggtgttt gtcaatcttc caggagagag ctacgatatt ggagaaatta tctctaggtt
    25501 tgagacaatg gggatagatg taactgtaaa tcttaaagca tttgataaga atttgggtcg
    25561 caataaacaa attcatgaga tggtaggatt gaatgtagtc actttctcta caaattttta
    25621 taaaactagt catgtgattt caaagagaat tctcgatatt tgtggtgcca ctattggcct
    25681 tattcttttt gctatagcta gtctagtttt agttccattg attcgtaaag atggcggatc
    25741 agctattttt gctcaaactc gtatagggaa aaatggtcga cattttacct tttataaatt
    25801 ccgttcgatg cgaatcgatg ctgaagctat caaagaacag ttgatggatc aaaatacgat
    25861 gcaaggtggt atgtttaaga tagacaatga tcctcgtgtt acaaaaattg gtcgctttat
    25921 tcgtaaaact agtttagatg aattgccgca gttttggaat gtctttatag gagatatgag
    25981 tttggtggga acacgtccac ctacagtaga cgagtatgat cagtatactc cagaacagaa
    26041 acgtcgactc agctttaaac ctggtattac aggtttatgg caggttagcg gccgtagtaa
    26101 aataaccgat tttgacgatg ttgtaaaatt agatgtggct tatattgata attggacaat
    26161 ctggaaagat attgaaattt tgcttaaaac tgttaaagtt gtatttatga gagatggagc
    26221 gaagtaattc atatgaatga gagaatgcaa atattaggag ttactataga tccattaacg
    26281 atgaaagaaa cagtggatgc tgttgaacag tatgttttaa agaagcatcc tttgcacttg
    26341 atgggagtta acgcagataa aattaatcag tgccatgaag atgagaaaat caaaaaaatc
    26401 gttaatgaat caggaatcat taatgcggat ggagcatcag ttgttcttgc aagtaagttt
    26461 ttaggaacgc ctgttcctga acgagtagcg ggtattgatt tgatgcaatg tcttttagag
    26521 ttgtcaaata aaaaaggata ttcagtttac ttttttggag ctaaagaaga aattttacaa
    26581 gatatgctaa aagtttttaa acaaagatat cctaatctta atgttgttgg ctatagaaac
    26641 ggatattttt cacctgaaga tgaaaaaaag attcaggaag atattaaagg aggaaaacca
    26701 gattttgtat ttgtagggat tacttctcct aaaaaggagt atatcatcca atcattcatg
    26761 gataatggga ttaatgctgt ctttatgggt gttggtggca gttttgatgt attatcagga
    26821 cacattaaac gagctccatt atggatgcaa aaattgaatc tggaatggtt gttccgtgta
    26881 gttaatgaac ccaaacgcct ttttaagcgt tattttatag ggaatgttac ttttattaag
    26941 cgagttttag atgaaaagcg aaaatcaaaa aaataatatt ctacatattt ctcgtacaat
    27001 ggatattggt ggtgcagaac gtattgtata tcaattgagt tctgatttga aagatgaatt
    27061 tgatagtgtc catgtcgctt caacaggtgg actatgggag agcaaacttt tatcaaaagg
    27121 agttcaacat cataaaattt tagatgttga cagtaagaat cccctaacta tggtaaagat
    27181 cctttcaagt ttttatagaa ttatcaaaaa taatgatatt accattgttc acactcatca
    27241 tcggatggct gccttttata ttcgcttgtt gaaaatcatt aatcctaagt tgatacatgt
    27301 ttacactgca cataatgtat ttaaaaataa attaccatta tacaaatttt ccttaaaaaa
    27361 agcgtattgt gtagctgtaa gtaaagcggt taatgataat ttgaaacatg atgtaggaat
    27421 cagtgatagt acagtaatct ataatggggt tgtttttgaa aaaactgata agctagttgg
    27481 tgaaattgta aactataacg gaatcaaatt ggggtgtatt gctaggttat cagagcaaaa
    27541 aggattgacc tacctaattg atgcgatgtc tttagtgaaa cacaggaata ttacgttgtt
    27601 cattgtcgga gatggagagc ttcgagatga gcttgaaaac aaggtgaaac aattaaatct
    27661 tcaaaaatca gtgatatttt taggttatcg aaaagatatt gttgaatgta tcaatagttt
    27721 tgattactta gtgtcatcat ctttatatga ggggtttggt ctaaatgcaa ttgaagcatt
    27781 tatgaagggg aaaacgatgg tttcatcaga tatcccagga ataaatgaag tagtcaataa
    27841 caaaaatggg attcttgttc ctgttaagga tgatgttgcc ttagcgagag cgattgaaaa
    27901 gcttgcgact gacaaaaaac ttagagaaaa actcgcttat caagcaaaaa aagattatga
    27961 gacaaaattt aattattcct tgtttttgga taattatcgg agactttata gaaaattaat
    28021 gggagaatca aaatgaaaaa agtcatgttg gtttttggga cacgtccaga agctattaaa
    28081 atgtgtcctt tagtaaatga actgaaacaa aatgattcaa tcaagacact tgtgtgtgta
    28141 actggtcaac ataaggaaat gttagagcag gttttagagg tgttcaaggt tgtcccagat
    28201 tatgatttgg gtatcatgaa agcaaatcag accctattta ccattacgac tagtatcttg
    28261 gataaaattc aggcggttct agagaaagaa aaaccagatc ttgttcttgt tcatggagat
    28321 actacaacaa catttgcgac agctttagca gcattttata tgggaatcaa agtgggacac
    28381 gtcgaagcag gtctcagaac ctataatctc caaagtccat ttccagagga attcaatcgc
    28441 cagacaactt ctatcattgc cgactatcat tttgcgccga ctgaagttgc gaaggaaaat
    28501 ctactaagag aggacagaaa aaatatcttt gtgacgggaa atacagtcat tgatgctttg
    28561 aagacgactg ttcaagataa ctaccatcac ccaattttag aatgggcaaa gggtagtaag
    28621 ttaatcatgc taacggctca tcgacgagaa aatcttggga aaccgatgga aaacatgttt
    28681 aatgctgtta atcgaatttt aaacgaattc gaagatgtaa aagttgtata tcccatccat
    28741 aaaaatccta aggttcgaga attagcaagt aaagtttttg gcgataatga acgaatgaaa
    28801 atcattgaac cgttagaggt tattgatttt cataatttta tgaatcaaag ctatatgatt
    28861 ttgacagatt ctggaggtgt acaggaagaa gcaccttctt taggaaaacc tgtcttggtg
    28921 atgcgtgata caacagagcg tcctgagggg gtcgttgctg gcacgttgaa gttggtagga
    28981 acagaagaag agaatatcta tagcaacttc aaacttcttc ttgaagatga aacagaatat
    29041 aacaagatga gcaaagctag caacccttat ggagatggaa tgacttgtaa acggattgtt
    29101 gatattattc tggaagtata aaaataattc aattatggat gaggaaagaa taaattagat
    29161 tgatgataaa aagaaaaata tatataatct gtgtattact gtcgtatttt ttacctagtt
    29221 tttttacagt tggatcaatg gcgactttat ttgctttgct ttctacttta gttaagctat
    29281 ttgtaacttt tgattatatt cccaaagttc ttttacagca taaagtaaca ctgattgata
    29341 ttctagttgt tctattttta ttttttcaag catttgcagc ttttcaaagc caaacgttgt
    29401 accttaacta tgttggaggt cagtttttcc ttttaggact atattcattt ttgaaacact
    29461 ttttattgtt ggattgtaaa acaacaataa aaagcctctt tttaaccttt atcttgtttt
    29521 tgtgtgttca agtaataact caattgcttt ttccggtcgg tttcgattct ttgcacccta
    29581 caggagataa tagactttac tttttaggaa gaaagaacat agctaccccg tatatcattg
    29641 ttggattagg tggtttttac ttattaaata aaaaaatgaa tgagtttata tcactaaagg
    29701 agattatttt tttaggattg ttcggaattt tatcattttt aacacaatcc agtacagcga
    29761 ttatatgtta tgggcttttt attttcatac gtctattggg attaaaggaa aatataggaa
    29821 aactatattc tttagtcagt atggctgtat atgtttgttt ttctctttct ataatctttt
    29881 cacaaagtac aattttatca acttttacag cgattttttc caaaaatgca actttttcag
    29941 gacgtatcaa tatttggcaa ttagcgattc gtatttttga agagaatttt tggtttggac
    30001 gaggcctcaa cgttaatttt aatgcttgga caaatgggat tatcgttaat tcagcacaca
    30061 ataccttatt agatatactt gctcgaactg gtatatttcc aggtgtttta tttatagtgc
    30121 ttcttatgaa tctgtttctt ggaaaatata gaatagaatc aaaaacactg ttggctatgt
    30181 tagcctcatt tatgatttat attacaatgg agacttcatc tatgagcata ttgctgctaa
    30241 ttattgttct ttgtgtatat tggccacgtg gagaggagaa gttgcatgag caagttactt
    30301 aataccatct attatcgact atttagatta tataaaaaaa tttatctaca agtttttagt
    30361 aaaaaaacgg ttgacatctt gggtgaaaag gctaatttag aaaatgaact aattgtttcg
    30421 tttacaacaa ttccaagtcg tcttaattat ttaccaagta tgattaaaag tattttcaat
    30481 cagacaatta tccctaaccg ttttattatg tatgtttata aagatgaatt tgaaggcatt
    30541 aatttggaga gtattctaga acttgaaatc aaaaatggtt tggaaattgt ctatgtggat
    30601 gagaatcttc gttcacacaa aaaatatttt tatgctatga aggataatcc gaacagtata
    30661 gttgttctag ttgatgacga tatcatttat cctcgaaata ctataaagaa actgattgca
    30721 tcctatagaa tttatccaca gtgtgtttca gcaatgcgat gtcatcgaat taagttgttt
    30781 tctgatggaa gtttatatcc atataatcaa tgggaatatg aaatatcagg agctactata
    30841 ccatcgtatt ttaatttttt tactagcgga ggtgggacat tatttcctcc atgtactcgc
    30901 aatgaggatc tttttaataa aaaaaatatc agggaactca gttttctagc tgatgatgta
    30961 tggttgaatt ttttggtagt caaaaatgga attaaaacag taaaagcaac acgatataaa
    31021 gggacaccat taactataga tgacaatcct gaggagagtt tggtatattt gaataccgta
    31081 tatgataaca acaatgataa atgtattaga aatatggttg aatattatca aattaatttt
    31141 acagaggata aataatgaat gttgaaaaaa atttgaaacg tggaattttc tatactgcaa
    31201 tagggaagta ttcgaatgta gttattcaat tacttgtaac agcaattctt agccggattc
    31261 tctcacctgt agaatatggt atcgtagcag tagtaaatgt atttctttta ttttttcaaa
    31321 tgttagcaga ttcaggaata ggacctgcta ttgttcaaaa taaagaactg aataagtcag
    31381 atttaatcag cattttctca ttaacgattt atagtggaat cgtactttct tgtatttttg
    31441 ctttactagg atatcctatg ggggtgttat acggcgaaac tatttatgtt agtttatttc
    31501 cgcttttagg tctttgtgtt ttattttata ccattacaat tgtaccgcaa gctattctaa
    31561 tgaaaacgat gaactttaaa atagttaatt ttctaactat tttttctaac attgctagtg
    31621 gcttggtggg cgttattcta gcggtatcac attttggtgt ctattctcta attttttcta
    31681 atattgtaaa agcaatggtt ttatttatcg ctttatattc taaagcaaag ataaatttct
    31741 attggaaagt ttcaaaaagt tctattggta aaatttttga gttttcaaaa ttccaatttt
    31801 tgtttaattt ttggaattat tttgctagaa atttagataa tttattaatt ggacgattga
    31861 ttagcccgtc agatcttggt tattatgata aggcttatca attatctttg taccctaatc
    31921 aaattttatc acaggttgtg acaccagcat tgcatcctat tatgtccaat tttcaagata
    31981 atatcagtaa gataggcgaa gtttatcttc agatttctag aatattcgta atagttggca
    32041 tacctatttc ggcttattta tactttaatg ctcaatatgt tgttacattt atgtttggag
    32101 ataattggtc ccaaagcgtt ccggtgtttc aaatattagc agcaacaatt tggttacaaa
    32161 tggctaatag ccctactggt gcattttacc aagcaactaa tcagacaaag ttattgttta
    32221 gaattggctt attgacatct tttattaata ttttagctat tgttattggt gtaatgttgc
    32281 aaagcatcca atgtgttgcg tacatgcttt tgatttcttt cagtcttagt ttagtaatca
    32341 atactcttta cttaacaaaa aaagtattaa atatttctgc tcaaaaatat ataaaaccga
    32401 tattaattaa tttgacaatt atcagtccct atattgtgtt taatttgttt atctcggatt
    32461 ttgtaaacga ccttatttta catttatcag ttcagtttgt tattttattt ttaatatggg
    32521 gaattgggat gtatattagc ggagagtatc gacgagtctt cgcggttata agaaaataaa
    32581 ggagcaattt tgtgaaaatt ttatttgtga atatgtttta taatgaagca ggaggtgcac
    32641 aaaagagcac caaatttcta gctgaacaac ttgtaaaaga aggacatgag gtatttgcat
    32701 actctgatga tgccattgat tcagatattg atgaagttat taatagggtt aagattttta
    32761 gaagaagaac cccgcttttt agtcttcact atattttcag tgctaagaag aatccagcta
    32821 aacatttttt ctataaaata tttgaaacct ataatgtatt tgcgaaaaga aaatttatca
    32881 atatcattga ggaagtacaa ccagatattg ttcactttaa tacaatttca ggaatgtctt
    32941 tatcaatagt taaagaagct aaaaagagaa atatcaggac cgtttggacc ttgcgagact
    33001 attggctaga atatccatgg ggtgagaaag atatttctct tatcaaactt ctaaatagaa
    33061 tatatagacc ttttgttaag aaaagtttaa gacacttaga catagtaaca gcaccatcag
    33121 catttacttt gaataatttt atcaataaag gatttattaa cccatcttct caaaaatgta
    33181 tggtcattga aaatgctgtt atattttcaa agggtaagtt ggaaaatatt atcaaacaaa
    33241 agcaagaaac aaaaagaaat ccagaaaaaa cgaattttct ttttgtaggt tctatacttg
    33301 aaataaaggg cgtttttaac ttagtaaagg cctttaaaaa actaactagt ccggaaattt
    33361 ctttgaaaat tgtaggaaaa ggaaaagatt tagaaaaact tcaaaaagaa attgagagtg
    33421 atcctagaat acaatattta ggctttcaag atacagaaac cctctataaa acttatcaaa
    33481 attcggatgt attggtcgtc ccatctgctt gggatgaacc gtttggtaga gttgtaattg
    33541 aaggaaatgc aaatggcctt cctgtcatca cttcagatag aggtggatta cctgaaattg
    33601 tgcaaacagt aggaggagga gaaattttta cagatgaatc gggaaataca ttatatagtc
    33661 ttttaaagaa atttgtagaa atggaaaact acaatgtcta ttaccaatgc attcttgaga
    33721 atattgatat ttattctatc gaaaaacaaa gtgaaaagtt cactaatctg tatttagata
    33781 aagaaatcga ataataagtt gtttttgtag cagtaacgga ggtaattatg aaaatagcgg
    33841 tagcaggaac aggttatgta ggattatcaa ttgctgtgtt gttggcacaa catcacgaaa
    33901 taaaagcagt tgatattgtt gctgaaaaag ttgaattaat caatcaaaaa aagtctccaa
    33961 ttcaggatga ttatattgaa aaatatttag tggaaaaaga tttaaatttg gaagcaacta
    34021 tggatgctaa gtatgcttat gaagatgcag aatttgttgt tgttgcagca ccaacaaatt
    34081 atgattcgaa aaagaacttt tttgatacat cagcagtaga ggcggtcatt caacaagtaa
    34141 aaaaaattaa tcccaaagcg gtaataatta ttaaatctac aatccctgtt ggattcacag
    34201 agtccgttca aaagaaatat cagtataaaa atatcttatt tagtccagaa tttttacgcg
    34261 aatctaaagc attatacgat aacctgtatc caagtcgcat cattgttgga actgacttag
    34321 aagatactta tttaaaagac aaagctaata tatttgcttc cctactaaaa gagggggcta
    34381 ttaaagaaga catagataca cttttcatgg gagtaacgga agctgaggca gttaaattat
    34441 ttgccaatac ctaccttgcg ttgcgtgttt cttactttaa tgaattggat acttatgcag
    34501 aggtgaaagg tttggatgca aaagccatta ttgatggtat tggcctagat ccacgtatag
    34561 gaaatcatta taacaatcca tcctttggct acggtgggta ttgtttacct aaagatagta
    34621 agcagttatt agcaaattac tttgatgtac cacaaaatat gatgacagca actgttgaaa
    34681 gcaatcgaac gcgtaaggat tttatcgctc aacggatttt agaaaaagct ggagtatctg
    34741 agactgatag tttagatgcg tttaagaaca tacaagatat tgttataggt atttatcgtt
    34801 taacaatgaa aagtaattcg gataacttcc gtcactcctc tattcaaggc gttatgaaac
    34861 gattgaaagc taagggagtt acggttatca tctatgagcc aactttgaag gacggggaaa
    34921 cattctttgg taataaagtg gtaaataatc tagataaatt taaagaagct agtaatgtta
    34981 ttgtagccaa tcgttttgaa ccttcactag aggatgtgtc taataaagtt tatagtcgag
    35041 atatatttaa gcgtgactaa taaatacgtc cacgtgacgt aatatctatt aaatgaataa
    35101 aatattaata aacatggcat cgatatcttt tttggacttg aattgtcaaa ttaagtgcac
    35161 atttttttca tagaaaactt cataaggtgt tttccggtta agacattttc gtggtctatt
    35221 atctaagttg gtttatataa tagacttcct gcgaaacaaa atatggtata atagttctat
    35281 gaattatgaa gcaagtaaac aactaaccga tgtacgattt aagcgtcttg ttggtgttca
    35341 acgcacgact tttgaagaga tgttagctgt attaaaaaca gcttatcaac ttaaacacgc
    35401 aaaaggtgga cgaaaaccta aattaagcct agaagacttt cttatggcga ctcttcaata
    35461 agtgcgagaa taccgcactt atgaacaaat tgcggctgat tttggtattc acgaaagcaa
    35521 cttaatccgt cggagctaat gggttgaagt aactcttgtt caaaggtggt gttacgattt
    35581 caagaactcc tctcagttct gaggacacgg taatgattga tgcgacggaa gtaaaaatca
    35641 atcgccctaa aaaaagaatt agcgaattat tctggtaaaa agaaatttca cgctatgaag
    35701 actcaagcga ttgtcacaag tcaagggaga attgtttctt tggatatcac tgtgaactat
    35761 tgtcatgata tgaagttgtt caaaatgagt cgcagaaata tcggacaagc tggtaaaatc
    35821 ttggctgaca gtggttatca agggctcatg aagatatatc ctcaagcaca aattccacgt
    35881 aaatccagca aactcaagcc gctaatagct gaagataaag cctataacca tgcactgtct
    35941 aaggatagaa gcaaggttga gaacatcctt gccaaagtaa aaacgtttaa aatgttttca
    36001 acaacctatc gaaatcatcg taaacgcttc ggatatttta ggcatactat atatttttta
    36061 ttcaattatt cacttttgta ttcaaaaggt tgcgggtgcc tctgtccgag tacccactat
    36121 gatatttaac ctattgaata tctataaatt tcctctggga gtttcatggt atctatatac
    36181 gttatggtcg atattgatag tttatggttt actatctgtt gttttcaaaa atcgtaagtc
    36241 ccttttgtta gttagtgttt ttgcctatat tttcacacta tttattcaaa ctgatatttt
    36301 tattgtgcaa cggacgttgg tttgggggat ttgtttcttt cttggcagtg tattgagtga
    36361 aattcacttt gataaaatta atttgaaaaa atttcttttt ttctttgtgt tatttgattt
    36421 tatttatatg ttcgcttggt tcttgtttta tgaagtaggg tctaagaagg attatgtaag
    36481 ctatattaac ccaggtttgt gggggattgc ttttattgtc tgtgtattag ttgcttttgc
    36541 gatttttcct aaaatggaga aaaattttcc taaaactttc ctatatttca ctaaatacgg
    36601 gaaagatagt ttagggatct atattcttca tgcaccaatt tgtagcatga ttcggattct
    36661 aatgttgaaa gtgggaataa actcagtttt tcttcacgtt gttgttggga ttgtgctagg
    36721 ctggtattta tccatactag caacttatat attgaaaaaa attccatttt tgaatattgt
    36781 tttattacca caaaagtata ttaaattaaa ataaattatt ttagatttat aatgtggctc
    36841 tttgtcaact aacatctgga gaggacaatc actgtcttct ctttttttgt cttttcagaa
    36901 tataccaaat taacacaaaa attctgaaaa ttctgttgac atctttctga aaagagttta
    36961 taatggagag aaagttttaa aggagaaaat gatgaaaagt tcaaaactat ttgcccttgc
    37021 gggcgtgaca ttattggcgg cgactacttt agctgcatgc tctggatcag gttcaagcac
    37081 taaaggtgag aagacattct catacattta tgagacagac cctgataacc tcaactattt
    37141 gacaactgct aaggctgcga cagcaaatat taccagtaac gtggttgatg gtttgctaga
    37201 aaatgatcgc tacgggaact ttgtgccgtc tatggctgag gattggtctg tatccaagga
    37261 tggattgact tacacttata ctatccgtaa ggatgcaaaa tggtatactt ctgaagggga
    37321 agaatacgcg gcagtcaaag ctcaagactt tgtaacagga ctaaaatatg ctgctgataa
    37381 aaaatcagat gctctttacc ttgttcaaga atcaatcaaa gggttggatg cctatgtaaa
    37441 agggggaatc aaagatttct cacaagtagg aattaaggtt ctggatgaac agacagttca
    37501 gtacactttg aacaaaccag aaagcttctg gaattctaag acaaccatgg gtgtgcttgc
    37561 gccagttaat gaagagtttt tgaattcaaa aggggatgat tttgccaaag ctacggatcc
    37621 aagtagtctc ttgtataacg gtccttattt gttgaaatcc attgtgacca aatcttctgt
    37681 tgaatttgcg aaaaatccga actactggga taaggacaat gtgcatattg acaaagttaa
    37741 attgtcattc tgggatggtc aagataccag caaacctgca gaaaacttta aagatggtag
    37801 ccttacagca gctcgtctct atccaacaag tgcaagtttc gcagagcttg agaagagtat
    37861 gaaggacaat attgtctata ctcaacaaga ctctattacg tatctagttg gtacaaatat
    37921 tgaccgtcag tcctataaat acacatctaa gaccagcgac gaacaaaagg catcgactaa
    37981 aaaggctctc ttaaacaagg atttccgtca ggctattgcc tttggttttg atcgtacagc
    38041 ctatgcctct cagttgaatg gacaaactgg agcaagtaaa atcttgcgta atctctttgt
    38101 gccaccaaca tttgttcaag cagatggtaa aaactttggc gatatggtca aagagaaatt
    38161 ggtcacttat ggggatgaat ggaaggatgt taatcttgca gattctcagg atggtcttta
    38221 caatccagaa aaagccaagg ctgaatttgc taaagctaaa tcagccttac aagcagaagg
    38281 tgtgacattc ccaattcatt tggatatgcc agttgaccag acagcaacta caaaagttca
    38341 gcgcgtccaa tctatgaaac aatccttgga agcaacttta ggagctgata atgtcattat
    38401 tgatatccaa caactacaaa aagacgaagt aaacaatatt acatattttg ctgaaaatgc
    38461 tgctggcgaa gactgggatt tatcagataa tgtcggttgg ggtccagact ttgccgatcc
    38521 atcaacttac cttgatatca tcaaaccatc tgtaggagaa agtactaaaa catatttagg
    38581 gtttgactca ggggaagata atgtagctgc taaaaaagta ggtctatatg actacgaaaa
    38641 attggttact gaggctggtg atgaggctac agatgttgct aaacgctatg ataaatacgc
    38701 tgcagcccaa gcttggttga cagatagtgc tttgattatt ccaactacat ctcgtacagg
    38761 gcgcccaatc ttgtctaaga tggtaccatt tacaatacca tttgcattgt caggaaataa
    38821 aggtacaagt gaaccaatct tatataaata cttggaactt caagacaagg cagtcactgt
    38881 agatgaatac caaaaagctc aggaaaaatg gatgaaagaa aaagaagagt ctaataaaaa
    38941 ggctcaagaa gatctcgcaa aacatgtgaa ataactgttg caaaatataa gaaaggattt
    39001 agtatttctc ttgaatgctg aatccttttt tacatttgta aagaaagatt ctaaatgtac
    39061 tgacccccaa aagttggagc ctctttttgt cagaatagag aaaatttttg ttaattttac
    39121 ttgtttccta ttgctttatc agttattatt tgttatatta aaagtataat tattttttat
    39181 ttatcagggt taagcattgc actttcagag gaaggagtat tttttaaaaa ggaaatgtaa
    39241 acgcttgccc aaaaatgaaa ggatttagaa gtttatgaat aaaggattat ttgaaaaacg
    39301 ttgtaaatat agtattcgga aattttcatt aggtgttgct tctgttatga ttggagctgc
    39361 attctttggg acaagtccgg ttcttgcaga tagcgtgcag tctggttcta cggcgaattt
    39421 accagctgat ttagctactg ctcttgcaac agcaaaagag aatgatgagc gtgattttga
    39481 agcgcctaag gtgggagaag accaaggttc tccagaagtt acagatggac ctaagacaga
    39541 agaagaacta ttagcacttg aaaaagaaaa accggctgaa gaaaaaccaa aagaggataa
    39601 acctgcagct gctaaacctg aaacacctaa gacggtaacc cctgaatggc aaacggtaga
    39661 gaaaaaagaa caacaaggaa cagtcactat ccgagaagaa aaaggtgtcc gctacaacca
    39721 actatcctca actgctcaaa atgataacgc aggcaaacaa gccctgtttg aaaagaaggg
    39781 cttgaccgtt gatgccaatg gaaatgcaac tgttgattta accttcaaag aagattctga
    39841 aaagggcaaa tcacgctttg gtgtcttctt gaaatttaaa gataccaata ataatgtttt
    39901 tgtcggttat gacaaggatg gctggttctg ggagtataaa tctccaacaa ctagcacttg
    39961 gtatagaggt agtcgtgttg ctgctcctga aacaggatca acaaaccgtc tctctatcac
    40021 tctcaagtca gacggtcagc taaatgccag caataacgat gtcaatctct ttgacacagt
    40081 gactctacca gctgcggtca atgaccatct taaaaatgag aagaagattc ttctcaaggc
    40141 gggctcttat gacgatgagc gaacagttgt tagcgttaaa acggataacc aagagggggt
    40201 aaaaacagag gatacccctg ctgaaaaaga aacaggtcct gaagttgatg atagcaaggt
    40261 gacttatgac acgattcagt ctaaggtcct caaagcagtg attgaccaag ccttccctcg
    40321 tgtcaaggaa tacagcttga atggacatac tttgccagga caggtgcaac agttcaacca
    40381 agtctttatc aataaccacc gaatcacccc tgaagtcact tataagaaaa tcaatgagac
    40441 aacagcagag tacttgatga agattcgcga tgatgctcac ttaatcaatg cggaaataac
    40501 agtacgcttg caagttgtgg acaatcaatt gcactttgat gtgaccaaga ttgtcaacca
    40561 caatcaagtc actccaggtc aaaagattga tgacgaaaga aaactacttt cttctattag
    40621 tttcctcggc aatgctttag tctctgtttc tagtgatcaa actggtgcta agtttgatgg
    40681 ggcaaccatg tcaaacaata cgcatgtcag cggagatgat catatcgatg taaccaatcc
    40741 aatgaaggat ttggctaagg gttacatgta tggatttgtt tctacagata agcttgctgc
    40801 tggtgtttgg agtaactctc aaaatagcta tggtggtggt tcgaatgact ggactcgttt
    40861 gacagcttat aaagaaacag tcggaaatgc caactatgta ggaatccata gctctgaatg
    40921 gcaatgggaa aaagcttata agggcattgt tttcccagaa tacacgaagg aacttccaag
    40981 tgctaaggtt gttatcactg aagatgccaa tgcagacaag aaagttgatt ggcaagatgg
    41041 tgccattgct tatcgtagca ttatgaacaa tcctcaaggt tgggaaaaag ttaaggatat
    41101 cacagcttac cgtatcgcga tgaactttgg ttctcaagca caaaacccat tccttatgac
    41161 cttggatggt atcaagaaaa tcaatctcca cacagatggt cttgggcaag gtgttctcct
    41221 taaaggatat ggtagcgaag gccatgactc tggtcacttg aactatgctg atattggtaa
    41281 gcgtatcggt ggtgtcgaag acttcaagac cctaattgag aaggctaaga aatatggagc
    41341 tcatctaggt atccacgtta acgcttcaga aacttatcct gagtctaaat acttcaatga
    41401 aaaaattctc cgtaagaatc cagatggaag ctatagctat ggttggaact ggctagatca
    41461 aggtatcaac attgatgctg cctatgacct agctcatggt cgtttggcac gttgggaaga
    41521 tttgaagaaa aaacttggtg acggtctcga ctttatctat gtggacgttt ggggtaatgg
    41581 tcaatcaggt gataacggtg cctgggctac ccacgttctt gctaaagaaa ttaacaaaca
    41641 aggctggcgc tttgcgatcg agtggggcca tggtggtgag tacgactcta ccttccatca
    41701 ctgggcagct gacttgacct acggtggcta caccaataaa ggtatcaaca gtgccatcac
    41761 ccgctttatc cgtaaccacc aaaaagatgc ttgggttggg gactacagaa gttatggtgg
    41821 tgcagccaac tatccactgc taggtggcta cagcatgaaa gactttgaag gctggcaagg
    41881 aagaagtgac tacaatggct atgtaaccaa cttatttgcc catgacgtca tgaccaagta
    41941 tttccaacac ttcactgtaa gcaaatggga aaatggtaca ccggtgacta tgaccgataa
    42001 cggtagcacc tataaatgga ctccagaaat gcgagtggaa ttggtagatg ctgacaataa
    42061 taaagtagtt gtaactcgta agtcaaatga tgtcaatagt ccacaatatc gcgaacgtac
    42121 agtaacgctc aacggacgtg tcatccaaga tggttcagct tacttgactc cttggaactg
    42181 ggatgcaaat ggtaagaaac tttctactga taaggaaaag atgtactact tcaatacgca
    42241 ggccggtgca acaacttgga cccttccaag cgattgggca aagagcaagg tttaccttta
    42301 caagctaact gaccaaggta agacagaaga gcaagaacta actgtaaaag atggtaaaat
    42361 tactctagat cttctagcaa atcaaccata cgttctctat cgttcgaaac aaaccaatcc
    42421 tgaaatgtca tggagcgaag gcatgcacat ctatgaccaa ggatttaaca gtggtacctt
    42481 gaaacattgg accatttcag gcgatgcttc taaggcagaa attgtcaagt ctcaaggggc
    42541 aaacgatatg cttcgtattc aaggaaacaa agaaaaagtt agtctcactc agaaattaac
    42601 tggcttgaaa ccaaatacca agtatgccgt ttatgtcggt gtcgataacc gtagtaatgc
    42661 caaggcgagc gtcactgtaa atactggtga aaaagaagtg actacttata ccaataagtc
    42721 tctcgccctc aactatgtaa aagcctacgc ccacaataca cgtcgtaaca atgctacagt
    42781 tgacgataca agttacttcc aaaacatgta cgccttcttt acaactggat cggacgtatc
    42841 aaatgttact ctgacattga gtcgtgaagc tggtgatcaa gcaacttact ttgatgaaat
    42901 tcgtaccttt gaaaacaatt caagcatgta cggagacaag catgatacag gtaaaggcac
    42961 cttcaagcaa gactttgaaa atgttgctca gggtatcttc ccatttgtag tgggtggtgt
    43021 cgaaggtgtt gaagataacc gcactcactt gtctgaaaaa cacaatccat atacacaacg
    43081 tggttggaat ggtaagaaag tcgatgatgt tatcgaagga aattggtcac tcaagacaaa
    43141 tggactagtg agccgtcgta acttggttta ccaaaccatc ccacaaaact tccgttttga
    43201 agcaggtaag acctaccgtg taacctttga atacgaagca ggatcagaca atacctatgc
    43261 ttttgtagtc ggtaagggag aattccagtc aggtcgtcgt ggtactcaag caagcaactt
    43321 ggaaatgcat gaattgccaa atacttggac agattctaag aaagccaaga aggcaacctt
    43381 ccttgtgaca ggtgcagaaa caggcgatac ttgggtaggt atctactcaa ctggaaatgc
    43441 aagtaatact cgtggtgatt ctggtggaaa taccaacttc cgtggttata acgacttcat
    43501 gatggataat cttcaaatcg aagaaattac cctaacaggt aagatgttga cagaaaatgc
    43561 tctgaagaac tacttgccaa cggttgccat gactaactac accaaagagt ctatggatgc
    43621 tttgaaagag gcggtcttta acctcagtca ggccgatgat gatatcagtg tggaagaagc
    43681 gcgtgcagag attgccaaga ttgaagcttt gaagaatgct ttggttcaga agaaaacggc
    43741 tttggtagca gatgactttg caagtcttac agctcctgct caggctcaag aaggtcttgc
    43801 aaatgccttt gatggcaatg tgtctagtct atggcataca tcttggaatg gtggagatgt
    43861 aggcaagcct gcaaccatgg tcttgaaaga accaactgaa atcactggac ttcgttatgt
    43921 tccacgtgga tcaggttcaa atggtaactt gcgtgatgtg aaacttgttg tgacagatga
    43981 gtctggcaag gagcatacct ttactgcaac tgattggcca gataacaata agccaaaaga
    44041 cattgatttt ggtaagacaa ttaaggctaa gaaaattgtc cttacaggta ctaagactta
    44101 cggagatggt ggcgataaat accaatctgc agcggaactt atctttactc gtccacaggt
    44161 agcagaaaca cctcttgact tgtcaggcta tgaagcagct ttggctaagg ctcagaaatt
    44221 aacagacaaa gacaatcaag aggaagtagc tagcgttcag gcaagcatga aatatgcgac
    44281 ggataaccat ctcttgacgg aaagaatggt ggaatacttt gcagattatc tcaaccaatt
    44341 aaaagattct gctacgaaac cagatgctcc aactgtagag aaacctgagt ttaaacttag
    44401 ctctttagtt tccaatcaag gtaagacgcc agattataag caagaaatag atagaccaga
    44461 aacacctgaa caaatcttgc cagcaacagg tgagagtcaa tctgacacag ccctcttcct
    44521 agcaagtgtt agtctagccc tatctgctct ctttgtagta aaaacgaaga aagactagta
    44581 tttagtaaaa cctcttaaca agattacgga agcagtctct atcttttcca atgaggttta
    44641 tagtacagaa aaagcctgag aagatgtctt ctcaggcttt tgttaagcac ataaatacaa
    44701 tagtgctatg acaaaatcac ccagaaaaat ctgggtgata aatgttatgg ttgtgctggt
    44761 tgaggattct gattttgttg atcaggggtt gtatttgatt gttgcgtatt attgttagga
    44821 ttggtagtcg tactattatt tgtgcttgga gtggttgagc tagactgtga agttgaacta
    44881 tctgatgatg agcttgaact ttcagttgat gggggttgtt gtggagcagg tgagttccac
    44941 gtagaacgag caccattttt aaatacgaat tctccatttc tgtagagccc ctctggtata
    45001 ttccaatcct ctggattgct tccttcagac agataggtca tcatagagcg gtaaactttg
    45061 gcagcgaccg taaggccatt gcctacaagt ggtgtcagac ggttagaata gcctgtccat
    45121 acagccattg aatatttacg cgtatagcca gcaaatagtt catcaggtgc tacaaattga
    45181 gaggtcttga tgtggttttc aatttcctcg tctgtatagt tagaggttcc tgttttacca
    45241 gcctgaggga gccaagcaag ataggcattt cgtccagttc cataactcaa gactgttttc
    45301 atcatgtcgg tcatcatata ggctgtcgtt tccttcatgg cacgagttcc gacattagag
    45361 aactcttttt cactcccatc actaaagacg actttatgga tatacattgg tttatagtaa
    45421 gttccaccat ttgcaaaggc agcgtaagca gcagccatct tttcactact tgctccatat
    45481 tttttgtctg attcggttgt gttacttgaa atggcatttg agtagtgaat acttgggtag
    45541 tcgattccga gaccatttag gaaagtcttg gcgcggttga gtccgacctt gtttagagtt
    45601 tccacggctg ggacgtttcg cgattgttgc agggcgtatt gcaaggtgat gttgccaaag
    45661 tagcccctat cccagttata aacaggggta tttgtcccag ggtagttata gggctcatcg
    45721 tgaacgatag tagcagttga atcgtagata ccgtactcca aggcaggagc atagtctgtg
    45781 atcggtttca tagttgatcc ccagtcgcgg tttgtttcta ctgcttggtt aattccgaag
    45841 gaaacattac ttgactgatg gcgtgctcct agctgggcaa tgactttacc gttagaaaca
    45901 tcaacaatgg tagaagcgac ttgcaattca tcgtctggat aggcaacgta ttcgtctgta
    45961 ttgtaaatat cccacagatg tttttgagct tcttggtcta catttgtgta gacatccatc
    46021 ccagttgtga gcaggttata gcctgtttct tcttcaactt gattgatgac ttccttgagg
    46081 taattatcca tgtaagcagg gtaattactt gctgatttga gactttgtag tccatcagta
    46141 attggtgtat tgactgcttt ctcatactgt tcagcagaga tgtagccttg atttttcatt
    46201 tcagataaga ccaagtttcg gcggtcttgg gctgcttctg gatgtgaata ggggtcatat
    46261 tggtttggtg cctgaggcat tccagccagc aaggctaact gaggtaaact taaattattg
    46321 aggtctttac catagtagtt ttgagctgct gtctgcattc catagttccc attagacatg
    46381 tagaccttat ttatatagta ggtcaagatt tcttgcttgg ttgctttttg ttctaactga
    46441 atcgctaacc aagcttcctg agccttacga gaaatagtct ggtcggaagt cgaagttgaa
    46501 aagtaagtca acttaatcaa ctgttgggtg agagttgatc caccttggag ggaattgctt
    46561 tgcagattgc gcaagaaagc tcctaggata cggatggtat caatccccct gtggtcgaag
    46621 aagcgatggt cttcgataga aacgattgcc ttaaccaaat ctgtgggaat atcattagct
    46681 tgggcattga cgcggcgttc agaacccaag tcagcaatga gttgattttt attgtcgtag
    46741 attttactag aagttgttgc aactagttta ctctcggata ggctaggagc cttgctaacg
    46801 tagtagaaaa aaactcctcc gcctaagaca atggctgcga taaccaagct taagaagcta
    46861 atgctcagat acttgattag gcgcagaatc gttggtttgt tcatcttgtt ttaccaccta
    46921 ataaatgttc tttgataaca ttgagataag gaatttgagg gaaggcacca gccttgattt
    46981 catatccata ttctcgaata tattcaagtg gcattgattt ttgtccctta tcttgatgat
    47041 agaagcgaat caaatcgaat gccggcaata agtaggtttc ttgctgagaa gaaaagtgaa
    47101 gaaggacaaa gcagattcct tgttgggcaa ggacttgttc catatgctga atctgatgtg
    47161 gatgaaaatt tttcatcgga atcgcacgtt tttgttttgt ttccttgact tcaaagtcga
    47221 tgtaatatcc attataaacg ccagaatagt ccgtcgttga agcttgtcga aaataggctt
    47281 caacaatctt ggcacgactt cgttgtggat agtccacttg tacgatttga ataggagttg
    47341 gtttcttatg tataacagcc aagccctgag acaaatagta gtcgttggta gcattgatca
    47401 tcttttcaaa agacattcct cgatttgcga aatttttggg ttgagaaaga gatgtttgtc
    47461 ttttttgtga tgaaacttta tgtggatagt tgaccataat tctccttatt ggtacaataa
    47521 catcacttta ttataccata atttgcacag aaagggttaa aaatggctac agctttggtt
    47581 ttaggctatt ctgcttttga tttgggttta ttttctgata aggatcctcg tcttaaattg
    47641 attaaaaaag cgatacgtaa agatttagag gctatggcag cagatggggt gtcttggctt
    47701 gtgtttacag ggagtttggg ttttgaatat tgggttttag aggttgctca ggagatgaaa
    47761 actgaatacg gtttccagtt ggccaccatt tttgcttttg aaacccatgg ggaaaattgg
    47821 aatgaaggca atcagatgaa actgagtcgc tttaagcagg tagactttgt caaatatgcc
    47881 tatcctcgct atgaacacaa ggggcagtta agagattacc agcagttttt gctggaaaac
    47941 acgactagtt cctatctttt ttatgatgaa gaaaatgaaa caaaactagc ttatttttac
    48001 caaaagatga aaaatcaaga ggactatttt ataaagagat taacatttga tgaattaaat
    48061 gaacttgctg aaaatttttc cgaaaattga agctttgacc ttgatttttg tttgcctttt
    48121 tttatataat aatactagca agcgagaatg gagagagaca tggcaagtat tattttttca
    48181 gcgaaagata tttttgaaca agagtttgga cgtgaagtcc gtggctataa taaagtagaa
    48241 gttgacgagt ttttagacga tgtcatcaag gactatgaaa cctatgctgc cttggtcaag
    48301 tcacttcgtc aggaaattgc ggatttgaag gaagaattaa ctcgtaaacc gaaaccttca
    48361 ccagttcaag cagaacccct tgaagcggca attacaagtt ctatgacgaa ttttgatatt
    48421 ttgaaacgcc tgaatagatt ggaaaaagaa gtttttggta aacaaatttt agataactca
    48481 gatttttaag tagttatttg agatgtgcaa tttttggata atcgcgtgag gagaattgct
    48541 tctcatgagg aaagtccatg ctagcacagg ctgtgatgcc tgtagtgttt gtgctaggcg
    48601 aaaccataag cctagggacg agaaatcgtt acggcagttg aaatggctaa gtccttggat
    48661 aggccagagt aggcttgaaa gtgccacagt gacggagtct ttctggaaac agagagagtg
    48721 gaacgcggta aacccctcaa gctagcaacc caaattttgg tcggggcatg gagtacgcgg
    48781 aaacgaacgt agtattctga ctgctatcag ctagagctgt tagtggtaga cagatgatta
    48841 tcgaaggaag tggtcctagt cacttctgga acaaaacatg gcttatagaa aattgcatat
    48901 aggttggggc tgagaaattt tctcaacctc attttttaaa gtggacatat agaaaggtct
    48961 tgcaagactg taacatgaaa aaagaattta atttaattgc aactgtggca gcagggcttg
    49021 aggctgtcgt tggtcgtgaa atgcgagagt tgggctacga ttgtcaggtt gaaaatggac
    49081 gtgttcgttt tcaaggagac gtgagagcta ttatcgaaac caacctttgg cttcgggcag
    49141 cagatcgtat caaaattatc gtaggaacgt tcccagctaa gacttttgaa gagctatttc
    49201 agggagtttt cgctttagat tgggaaaatt atttaccact tggagctcgg ttcccgattt
    49261 caaaagctaa atgtgttaag tccaaacttc acaatgagcc cagtgttcag gctatttcta
    49321 agaaagctgt tgtcaagaaa ttgcagaaac actatgctcg cccagaaggg gttcctctga
    49381 tggagaatgg tccagagttt aagattgagg tctctattct caaagatgtg gcaactgtca
    49441 tgattgatac gaccgggtct agcctcttta aacgtggtta tcgtaccgaa aaaggtggcg
    49501 ctcctatcaa ggaaaatatg gcagcagcca ttttacaact ttctaactgg tatccagaca
    49561 agcctttgat tgatccgacc tgtggttcgg ggactttctg tattgaggca gttatgattg
    49621 ctagaaagat ggcgccaggt cttcgtcgtt cttttgcatt tgaggaatgg aactggatca
    49681 gcgatcgctt gattcaagaa gtgcgcacag aagcggctaa aaaagtagac cgtgagcttg
    49741 agctggatat catgggctgt gatattgatg ctcgcatggt ggaaattgct aaggccaatg
    49801 ctcaggtagc tggtgttgca ggagacatta cttttaagca gatgcgcgtg caggatttat
    49861 gttccgataa aatcaatgga gtaatcattt ccaatccgcc ttatggtgaa cgtttgtcag
    49921 atgatgcagg ggtgaccaag ctctatgctg agatggggca agtatttgca ccgctgaaaa
    49981 cttggagcaa atttatcctg actagtgatg aagcttttga aagcaagtat ggtagccaag
    50041 cagataagaa gcgtaagtta tacaacggaa ccttgaaagt ggatctatat caatattttg
    50101 gtcagcgtgt caaacggcaa gaggtaaaat agaaagggat actcatgagt aaaaaaagac
    50161 gaaatcgtca taaaaaagaa ggtcaagaac cgcaatttga ttttgatgaa gcaaaagagc
    50221 taacagttgg tcaagctatt cgtaaaaatg aagaagtgga agcaggagtc ttgcctgagg
    50281 attccatttt ggacaagtat gttaagcaac acagagatga aattgaggcg gataagtttg
    50341 cgactcgtca atacaaaaaa gaggagttcg ttgaaactca gagtctggat gatttaattc
    50401 aagagatgcg tgaggctgta gagaagtcag aagcttcttc ggaggaagtt ccatcttctg
    50461 aagacatctt actacccttg cctctggacg atgaggagca aggcttggat cctctattgc
    50521 tagatgatga aaatccaaca gaaatgactg aagaagtgga agaggagcaa aacctttctc
    50581 gtctggatca agaggactca gaaaagaaaa gtaaaaaagg ctttattttg accgttttgg
    50641 cgcttgtatc agtaattatt tgtgtcagtg cttattatgt ctaccgtcaa gtggctcgtt
    50701 cgactaagga aattgaaact tctcaatcaa ctacagccaa tcaatcggat gtggatgatt
    50761 ttaatacact ttatgacgcc ttttacacag atagcaataa aacggctttg aaaaatagcc
    50821 agtttgataa actgagtcaa ctcaagactt tacttgataa gctggaaggt agtcgtgaac
    50881 atacgcttgc caaatctaaa tatgatagtc tagtaacgca aattaaggcc attcaagatg
    50941 tcaatgcaca atttgaaaaa ccagctattg tggatggtgt gttggatacc aatgccaaag
    51001 ccaaatcgga tgctaaattt acagatatta aaactgggaa tacggagctt gataaagtgc
    51061 taggtaaggc tatcagtctt ggtaagagcc agcaaacaag tacttctagc tcaagttcaa
    51121 gtcaaactag cagctcaagc tctagtcaag caagctcaaa tacgactagt gagccaaaac
    51181 caagtagttc aaatgagact agaagtagtc gcagtgaagt caatatgggt ctctcgagtg
    51241 caggggttgc tgttcaaaga agtgccagtc gtgttgccta taatcagtct gctattgatg
    51301 atagtaataa ctctgcctgg gattttgcgg atggtgtctt ggaacaaatt ctagcaactt
    51361 cacgttcacg tggctatatc actggagacc aatatatcct tgaacgtgtc aatatcgtta
    51421 acggcaatgg ttattacaac ctctacaagc cagatggaac ctatctcttt acccttaact
    51481 gtaagacagg ctactttgtc ggaaatggcg ctggtcatgc ggatgacttg gattactaag
    51541 cagtcgttac aaaattcttt cttttcaaaa gtaaaaatga taaaataaaa caaatgaaac
    51601 aagaggagtg tcaaatgaca aaagctaact ttggtgttgt aggtatggcc gtaatgggtc
    51661 gtaaccttgc ccttaatatt gaatcacgtg gttacacagt tgctatctac aaccgtagta
    51721 aagaaaaaac ggaagatgtg attgcttgcc atcctgaaaa gaactttgta ccaagctatg
    51781 acgttgaaag ttttgtaaac tcaatcgaaa aacctcgtcg tatcatgctg atggttcaag
    51841 ctggacctgg tacagatgct actatccaag cccttcttcc ataccttgac aagggtgata
    51901 tcttgattga cggtggaaat actttctaca aagataccat ccgtcgtaat gaagaattgg
    51961 caaactcagg tatcaacttt atcggtactg gggtttctgg tggtgaaaaa ggtgcccttg
    52021 aaggtccttc tatcatgcct ggtggacaaa aagaggccta cgaattggtt gcggatgttc
    52081 ttgaagaaat ctcagctaaa gcaccagaag atggcaaacc atgtgtgact tacatcggcc
    52141 ctgatggagc tggtcactat gtgaaaatgg ttcacaatgg tattgagtac ggtgatatgc
    52201 aattgatcgc agaaagctat gacttgatgc aacacttgct aggcctttct gcagaggata
    52261 tggctgaaat ctttactgag tggaacaagg gtgaattaga cagctatttg atcgaaatca
    52321 cagctgatat tttgagccgt aaagacgatg aaggccaaga tggaccaatc gtagactaca
    52381 tccttgatgc tgcaggtaac aagggaactg gtaaatggac tagccaatca tctcttgacc
    52441 ttggtgtacc attgtcactg attactgagt cagtgtttgc acgctacatt tcaacttaca
    52501 aagaagaacg tgtacatgct agcaaggtgc ttccaaaacc agctgccttc aactttgaag
    52561 gagacaaggc tgaattgatt gaaaagatcc gtcaagccct ttacttttca aaaatcattt
    52621 catacgcaca aggatttgct caattacgtg tagcctctaa agaaaacaac tggaacttgc
    52681 catttgcaga tatcgcatct atctggcgtg atggctgtat catccgttct cgtttcttgc
    52741 aaaagattac agatgcttac aaccgtgatg cagaccttgc caaccttctt ttggatgaat
    52801 acttcttgga tgttactgct aagtatcaac aagcagtgcg tgatatcgta gctcttgcgg
    52861 ttcaagctgg tgtgccagtg ccaactttct cagcagctat tacttacttt gatagctacc
    52921 gttcagctga ccttccagct aacttgatcc aagcacaacg tgactacttt ggtgctcaca
    52981 cttaccaacg taaagacaaa gaaggaacct tccactactc ttggtatgac gaaaaataag
    53041 taggtcagcc atggggaaac ggattttatt acttgagaaa gaacgaaatc tagctcattt
    53101 tttaagtttg gaactccaga aagagcagta tcgggttgat ctggtagagg aggggcaaaa
    53161 agccctctcc atggctcttc agacagacta tgatttgatg ttattgaacg ttaatctggg
    53221 agatatgatg gctcaggatt ttgcagaaaa attgagccga actaaacctg cctcagtcat
    53281 catgatttta gatcattggg aagacttgca agaagagctg gaagttgttc agcgttttgc
    53341 agtttcatac atctataagc cagtccttat cgaaaatctg gtagcgcgta tttcggcgat
    53401 cttccgaggt cgggacttca ttgatcaaca ctgcagtctg atgaaagttc caaggaccta
    53461 ccgcaatctt aggatagatg ttgaacatca cacggtttat cgtggtgaag agatgattgc
    53521 tctgacccgc cgtgagtatg accttttggc gacacttatg ggaagcaaga aagtattgac
    53581 tcgtgagcaa ttgttggaaa gtgtttggaa gtatgaaagt gcgaccgaga caaatatcgt
    53641 agatgtctat atccgctatc tacggagcaa gcttgatgtt aaaggacaaa aaagctacat
    53701 taaaactgtg cgtggtattg gatataccat gcaagaatag aaaagcagtt gcagttgtgt
    53761 aactgctttt ttgaggagtt tttatatatt gacatgcagt cgggtctttg ctacaatcgt
    53821 tttaggagga tatatagatg aaacttttga aaaaaatgat gcaagttcta ctagcagtct
    53881 ttttctttgg tttgctagct acaaatacgg tatttgcgaa taccacaggt ggccgatttg
    53941 ttgataagga taatagaaaa tattatgtaa aagatgatca taaagcaatc tattggcata
    54001 aaatagacgg taaaacttac tattttggtg atattggaga gatggttgtc ggttggcaat
    54061 acttagaaat tcctggaaca ggttatcgtg ataatttatt cgataaccaa ccagttaatg
    54121 aaattggcct tcaggagaag tggtactatt ttggacaaga tggtgctttg ctagaacaaa
    54181 cagataaaca agtactagag gcaaaaacgt ctgaaaatac aggaaaagta tacggtgaac
    54241 aatatcctct atctgctgaa aagagaactt attattttga taataattat gctgtaaaga
    54301 caggctggat ttatgaagag ggtcattggt attatttaaa taagctagga aattttggcg
    54361 atgattctta caatccacta ccaattggtg aagttgctaa gggttggact caagattttc
    54421 atgttactat tgacattgat agaagcaaac ctgctccatg gtactaccta gatgcttcag
    54481 gtaagatgct tacagattgg caaaaagtaa acggaaaatg gtattatttt ggctcctctg
    54541 gttctatggc aacaggttgg aaatatgtac gaggcaaatg gtattactta gataataaaa
    54601 atggtgatat gaaaacagga tggcaatacc ttggtaacaa gtggtactac ctccgttcat
    54661 caggagctat ggtaactggc tggtatcaag atggttcaac ttggtactat ttagatcctt
    54721 ctaatggaga tatgaaaata ggttggacaa aagtaaatgg aaaatggtat tatctcaatt
    54781 caaatggagc aatggttaca ggtagccaaa ctatcgatgg taaagtttat aatttcgcct
    54841 catctggtga gtggatttaa tattggaggg tatatagatg aaaattttga aaaaaactat
    54901 gcaagttgga ctgacagtat ttttctttgg tttgctaggg accagtacag tatttgcaga
    54961 tgattctgaa ggatggcagt ttgtccaaga aaacggaaga acctactaca aaaaggggga
    55021 cctcaaagaa acctactggc gagtgattga tggtaagtac tattattttg attctctatc
    55081 tggagagatg gttgtcggct ggcaatatat cccgtttcca tctaaaggta gtacaattgg
    55141 tccttaccca aatggtatca gattagaagg ttttccaaag tcagagtggt actacttcga
    55201 taaaaatgga gtgctacaag agtttgttgg ttggaaaaca ttagagatta aaactaaaga
    55261 cagtgttgga agaaagtacg gggaaaaacg tgaagattca gaagataaag aagagaagcg
    55321 ttattatacg aactattact ttaatcaaaa tcattcttta gagacaggtt ggctttatga
    55381 tcagtctaac tggtattatc tagctaagac ggaaattaat ggagaaaact accttggtgg
    55441 tgaaagacgt gcggggtgga taaacgatga ttcgacttgg tactacctag atccaacaac
    55501 tggtattatg caaacaggtt ggcaatatct aggtaataag tggtactacc tccgttcctc
    55561 aggagcaatg gccactggct ggtatcagga aggtaccact tggtattatt tagaccaccc
    55621 aaatggcgat atgaaaacag gttggcaaaa ccttgggaac aaatggtact atctccgttc
    55681 atcaggagct atggcaactg gttggtatca agatggttca acttggtact acctaaatgc
    55741 aggtaatgga gacatgaaga caggttggtt ccaggtcaat ggcaactggt actatgctta
    55801 tagctcaggt gctttggcag tgaatacgac cgtagatggc tattctgtca actataatgg
    55861 cgaatgggtt cggtaatgac agggcgctta taattatatt agaacactcg cttaatcaaa
    55921 gaagtgactt tgttgtactt gacctgacga ttggggagat taaaagcatg tgaaatctac
    55981 acatgctttt tcgttagtta tgagtgttga acttgactaa ccattgacaa aagataagag
    56041 caattaaaat aagatacaaa aatatcaatg ctaactgcac cgaaacgccc gatgctatgg
    56101 atagggctaa tagggagagc agggacgggg cgagaatgtc cactgtgctc agagcagagc
    56161 ccaccgtccc catcttgtca ctggggatat gggcaaagac agctgcttgt aggcgagggc
    56221 tgagaatgcc gataatcgta gaactgatga aactggtcat gaaaattacg atataggctt
    56281 gacaaaggat actagttatt agagtcaata gggaaatctc acagaaaacc aagaggtgcg
    56341 tgaaacggat atttttaaat agattactgc tggtcatatt gccaaggata gctccacaag
    56401 acatgatgat ggagagcagg gcgaggagtt gcccaatgct cagttgtgct agtgtctgtt
    56461 ggatgaagcg gagggcaatc agccgagggg acacatccaa gatggcaatc atactggtcg
    56521 tcagaaacag tagtatgacg gtatctttta acctcaggag cacagccagc gactgtttaa
    56581 gatgttgaaa atatttctta aaactcagtg ctgtatgtga catttcaatt cttttttcaa
    56641 cctcatacaa ggtatgtcga ataacataca ggcccaaaaa ggcaatgaca aaagtcagag
    56701 tgttgataag ggaaatagtt tgaatactta taacattgat aaggaatgcg ccagccagat
    56761 tggcgacaat acggacaacc ctcatcagag actgcctgaa ccccatggca tcatgcaggt
    56821 cgtccttaat tacactgatg tagagggcgt tcatcatgta ggcagacagg tagctcaagg
    56881 tgtcagagat gaggttgatg atgacaatca taatgactga aactaatgaa aagggcgaca
    56941 agacgagaaa tactgtcaaa atagcgtaga gcaggatttt gattttggca atccagagtg
    57001 cgtgtttgac tctattttct tgaaaatctc ctagaatccc gagaaagagt tgcgatagta
    57061 ggggaaccat ctctgaaatg gaaatcagta aaatcgctag cggagcgaaa ttgtactgag
    57121 ccacataatt gataatggcg aggtagaaaa tactgtcgcc gaatgatgaa aaacagctgt
    57181 ttagcagcaa ctgtctatat atgttgtttg tccaaaataa tttcatactt ttctccttat
    57241 gtctgcacat cgaatgggaa tttattattt aatagacacc aatatacccc atgcttccta
    57301 ttccgaagtc aaacaaatct gctttaccac tatctccttg aaacataagt aaaccgtgat
    57361 catctcgttc agaacatgct aaaattacct gttggatttt tttcatcagt aatttgtttt
    57421 gattgtagac agtggtttgt agtaagctag ttattccgtg gcaatatcct gtcatcattt
    57481 ttagatgatg gttaaaaaca aattcttgat atttactaat aatatctttg tttccgtcac
    57541 aatcgtacat acaaagatat aagattattc cggaaattcc tttgcaccaa gaaagttgta
    57601 aatttcctaa attttcagta ttagaagtaa ctttttctaa taattttttt aattcagtat
    57661 ggaatgtatg gagatcatta tagaacatag aaggttctaa gactttagaa taggcaaata
    57721 aagcatatgc aattccacaa tatccatgag caaagctata gtctaaaatg ctttctttgg
    57781 ctgtatctct ttgtaggaaa taatgataaa tttcccctat actattgtgg atgaaaattt
    57841 taagagtatt gtcattggta aattgatagt attttattaa tgataatagg acaccagatt
    57901 ttcccaatgc aaagtctatt tcctctagag tatcataatt ctctattaat tttttagcgg
    57961 tgacgtttgc taattgtaga tagtattgat ttttactgat agaaaataaa tgtaggagta
    58021 accatagata gcctgcatca ccaaatagca gtgagtattg atattcatat gtgtgtgtcg
    58081 ttctaattgt cactgccttc ttgatgatag agagtatttt agaatccagt tctggggggt
    58141 acaatttatt tagaggaaac agtagtccag ctattccgtg ttggaatgat aaattactta
    58201 cgaaatttcc aaattctgtt gaagaagtga tccttccttc agaatttaca gttttatcta
    58261 gtaaaaattg tagaacacta ttacattctg ttttgtaatc atatttatgt tcctctattt
    58321 ttttaatttt gactaaatta tttgtttgac ttaaatttag tagacattgt aaccaaaata
    58381 gttgctcatc tgtgagctga ccttgagtat gtgatagttc tagtaattga ataggatcct
    58441 ttagttagat tcaatcaatc tataacacaa caacataata atacttttag gataacttat
    58501 caaatattat agtaaaatga gataataaca ggataaatcg atcaggacag tcaaatcgat
    58561 ttctaacaat attttagaag tagaggtgta ctattctagt ttcaatctac tatagtatat
    58621 atttttacat cttgaattgt caaattaagt gcataacttt cccgtagcat acttcataag
    58681 gcgttttcca cttaagaaat tttcgtggtc gattatttag aacctgtatt cacaaaaaat
    58741 gttaaactag agttatgaca cgcaaagtat atgatactga tttaaacgat caagaatggg
    58801 ctaagattga accctatttc tccaaacacc gcacctataa atgaccgaaa cgagtacttg
    58861 ttaatgagac tttgtacgtc actaaaacag gttgtcaatg gcgcatgctc cctcacgact
    58921 ttcctcttta cttaatggta tggagtttct ttcgtcgttc tatgacgaca ggttggttcc
    58981 aggtcaatgg cagatggtac tacgcttata gctcaggtgc cttggcagtg aatacgaccg
    59041 tagatggcta ttttgtcaat tataatggcg aatgggttca ataatgaaag aagcgattgt
    59101 gaatggaaac aatcgctttt tttgtgaaaa tataataaaa tagataggaa agaattaata
    59161 cttgtatgaa aaataagacg ttttttcgtc tagtaaaagg aaaaaatgac aaaaaaagtt
    59221 ggtgtcggtc aggcacatag taagataatt ttaatagggg aacatgcggt cgtttacggt
    59281 tatcctgcca tttccctgcc tcttttggag gtggaggtga cctgtaaggt agttcctgca
    59341 gagagtcctt ggcgccttta tgaggaggat accttgtcca tggcggttta tgcttcactg
    59401 gagtatttgg atatcacaga aacctgcgtt cgttgtgaga ttgactcggc tatccctgag
    59461 aaacggggga tgggttcgtc agcggctatc agcatagcgg ccattcgtgc ggtatttgac
    59521 tactatcagg ctgatctgcc tcatgatgta ctagaaatct tggtcaatcg agctgagatg
    59581 attgctcata tgaatcctag tggtttggat gctaagacct gtctcagtga ccaacctatt
    59641 cgctttatca agaacgtagg atttacagaa cttgagatgg atttatccgc ctatttggtg
    59701 attgccgata cgggtgttta tggtcatact cgtgaagcca tccaagtggt tcaaaataag
    59761 ggcaaggatg ccctaccgtt tttgcatgcc ttgggagaat taacccagca agcagaagtt
    59821 gcgatttcac aaaaagatgc tgaaggactg ggacaaatcc tcagtcaagc gcatttacat
    59881 ttaaaagaaa ttggagtcag tagccctgag gcagactttt tggttgaaac gactcttagc
    59941 catggtgctc tgggtgccaa gatgagcggt ggtgggctag gaggttgtat catagccttg
    60001 gtaaccaatt tgacacacgc acaagaacta gcagaaagat tagaagagaa aggagctgtt
    60061 cagacatgga tagagagcct gtaacagtac gttcctacgc aaatattgct attatcaaat
    60121 attggggaaa gaaaaaagaa aaagagatgg tgcctgctac tagcagtatt tctctaactt
    60181 tggaaaatat gtatacagag acgaccttgt cgcctttacc agccaatgta acagctgacg
    60241 aattttacat caatggtcag ctacaaaatg aggtcgagca tgccaagatg agtaagatta
    60301 ttgaccgtta tcgtccagct ggtgagggct ttgtccgtat cgatactcaa aacaatatgc
    60361 ctacggcagc gggcctgtcc tcaagttcta gtggtttgtc cgccctggtc aaggcttgta
    60421 atgcttattt caagcttgga ttggatagaa gtcagttggc acaggaagcc aaatttgcct
    60481 caggctcttc ttctcggagt ttttatggac cactaggagc ctgggataag gatagtggag
    60541 aaatttaccc tgtagagaca gacttgaaac tagctatgat tatgttggtg ctagaggaca
    60601 agaaaaaacc aatctctagc cgtgacggga tgaaactttg tgtggaaacc tcgacgactt
    60661 tcgacgactg ggttcgtcag tctgagaagg actatcagga tatgctgatt tatctcaagg
    60721 aaaatgattt tgccaagatt ggagaattaa cggagaaaaa tgccctggct atgcatgcta
    60781 cgacaaagac tgctagtcca gccttttctt atctgacgga tgcctcttat gaggctatgg
    60841 actttgttcg ccagcttcgt gagaaaggag aggcctgcta ctttaccatg gatgctggtc
    60901 ccaatgttaa ggtcttctgt caggagaaag acttggagta tttgtcagaa attttcggtc
    60961 agcgttatcg cttgattgtg tcaaaaacaa aggatttgag tcaagatgat tgctgttaaa
    61021 acttgcggaa aactctattg ggcaggtgaa tatgctattt tagagccagg gcagttagct
    61081 ttgataaagg atattctcat ctatatgagg gctgagattg ctttttctga cagctaccgt
    61141 atctattcag atatgtttga tttcgcagtg gacttaaggc ctaatcctga ctacagcttg
    61201 attcaagaaa cgattgcttt gatgggagac ttcctcgctg ttcgtggtca gaatttaaga
    61261 cctttttctc tagaaatctg tggcaaaatg gaacgagaag ggaaaaagtt tggtctaggt
    61321 tctagtggca gcgtcgttgt cttggttgtc aaggctttac tggctctgta tgatgtttct
    61381 gttgatcagg agctcttgtt caagctgact agcgctgtct tgctcaagcg aggagacaat
    61441 ggttccatgg gcgaccttgc ctgtattgtg gcagaggatt tggttctcta ccagtcattt
    61501 gatcgccaga aggtggctgc ttggttagaa gaagaaaact tggcgacagt tctggagcgt
    61561 gattggggct tttcaatttc acaagtgaaa ccaactttag aatgtgattt cttagtggga
    61621 tggaccaagg aagtggctgt atcgagtcac atggtccagc aaatcaagca aaatatcaat
    61681 caaaattttt taacttcctc aaaagaaacg gtggtttctt ttgaggaagc cttggaacag
    61741 gggaaatcag aaaagattat cgagcaagta gaagtagcca gcaagctttt agaaggcttg
    61801 agtacagata tttacacgcc tttgcttaga cagttgaaag aagccagtca agatttgcag
    61861 gccgttgcca agagtagtgg tgctggtggt ggtgactgtg gcatcgccct gagttttgat
    61921 gcgcaatcaa ccaaaacctt aaaaaatcgt tgggccgatc tggggattga gctcttatat
    61981 caagaaagga taggacatga cgacaaatcg taaggacgag catatcctct atgcccttga
    62041 gcagaaaagt tcctataata gctttgatga ggtggagctg attcattctt ccttgcctct
    62101 ttacaatctg gatgaaatcg atctttcgac agagtttgct ggtcgaaagt gggactttcc
    62161 tttttatatc aatgccatga ctggtggaag taataaggga agagaaatca atcaaaagct
    62221 ggctcaggtg gcggaatcct gtggtatttt atttgtaacg ggttcttata gcgcagccct
    62281 caaaaatcca acggatgatt ctttttctgt caagtctagt catcccaatc tcctccttgg
    62341 aaccaatatt ggattggaca agcctgtcga gttaggactt cagactgtag aagagatgaa
    62401 tcctgttcta ttgcaagtgc atgtcaatgt catgcaggaa ttactcatgc ccgagggaga
    62461 aaggaagttt agaagctggc aatcgcatct agcagattat agcgagcaaa ttcccgttcc
    62521 tattgtcctc aaggaagtgg gctttggaat ggatgccaag acaatcgaaa gagcctatga
    62581 attcggtgtt cgtacagtgg acctatcggg tcgtggtggc accagctttg cctatatcga
    62641 aaaccgtcgt agtggccagc gtgattacct caatcaatgg ggtcagtcta ccatgcaggc
    62701 ccttctcaat gcccaagaat ggaaagataa ggtcgaactc ttggttagtg gaggggttcg
    62761 gaatccgctg gatatgatta agtgcttggt ttttggtgct aagtctgtgg gattgtcacg
    62821 aaccgttctg gaattggttg aaacctacac agttgaagaa gtgattggca ttgtccaagg
    62881 ctggaaagca gacctacgct tgattatgtg ttcccttaac tgtgccacca tagcagatct
    62941 acaaaaagta gactatcttc tttatggaaa attaaaagaa gcaaaggatc agatgaaaaa
    63001 ggcgtaacca gcgccttttt tccatcctca gactgaggtg acttttttga attgtgataa
    63061 aatagaaggg agaggatgaa cctatgagaa aatttaaaat ctttttattt atcgaagcct
    63121 gtcttctgac aggagctctg attttgatgg tatcagagca tttttcgcgt tttctgctga
    63181 tactattcct ctttttgctt ttgattcgct actacactgg taaagaggga aataatcttc
    63241 ttttagtagc ggcaaccatt ctcttctttt tcatcgttat gctcaatcct tttgtgattc
    63301 tagctatttt tgttgcggtt atctatagcc tctttcttct ttacccgatg atgaaccagg
    63361 aaaaagagca gaccaatttg gtttttgaag aggtcgtgac ggttaagaag gagaaaaatc
    63421 gttggtttgg aaatcttcat catttttcaa gctaccagac ttgccaattc gatgatatca
    63481 atctctttcg cttcatgggc aaggacacta ttcatctgga gagggtcatc ttaaccaatc
    63541 atgacaatgt cattatcctc agaaagatgg taggaacgac caaaatcatc gtacctgtag
    63601 atgtggaagt cagtctcagc gttaactgtc tctatgggga tttgactttt ttcaaccagc
    63661 ccaagcgagc cctccgcaat gaacactatc atcaagaaac aaaagactat ctcaagagta
    63721 acaagagtgt caagattttc ttgaccacta tgattggtga tgtggaggtg gttagaggat
    63781 gaaaaaacaa gcctatgtca ttattgctct cacctccttc ctgtttgtct tttttttctc
    63841 ccacagcttg ctggaaatac ttgattttga ctggtctatc tttttgcacg atgtcgaaaa
    63901 aacagaaaaa tttgtctttt tattgttggt tttcagcatg tccataacct gtctcttagc
    63961 cctgttttgg cgagggatcg aagagctttc tctaagaaaa atgcaggcta atctcaagcg
    64021 tttattggca gggcaagaag tggttcaggt tgcagatcca gatttggatg ccagtttcaa
    64081 gtccttatca ggtaaactta accttttgac agaagctctt caaaaagctg aaaatcagag
    64141 ccttgctcag gaagaggaaa tcatcgagaa ggaacggaag cgaattgctc gggatttgca
    64201 cgatacagtc agtcaggagt tgtttgcggc ccacatgatt ttatcgggta tcagtcagca
    64261 ggctttgaaa ttggatagag aaaagatgca gatccagttg cagagtgtca cagctatttt
    64321 agaaacagcc cagaaggatt tgcgggtttt gctcttgcat ttgcgaccag ttgaactgga
    64381 gcagaagagc ttgatagaag ggattcagat tctcttaaaa gagcttgagg acaagagtga
    64441 tcttagggtt agtctcaagc agaatatgac gaaattgcct aagaaaatcg aggagcatat
    64501 cttccgtatc ctgcaagagt tgattagcaa taccctccgc catgcccagg catcttgcct
    64561 agatgtctac ctctatcaga cagatgttga attgcaactg aaggtggtgg acaatgggat
    64621 tggtttccag ttagggagct tagacgactt gagttatgga ctgcgaaata tcaaggagcg
    64681 ggttgaagat atggctggaa cagttcaact cttgacagct cccaagcaag ggctggcggt
    64741 tgatatccgt attcccctgt tagataagga atgataaagg agtaaagatg aaaattttac
    64801 tagtagatga ccatgaaatg gtccgattgg gcttgaaaag ctactttgac ctccaagacg
    64861 atgtagaagt tgtgggtgag gcgtccaacg ggtctcaagg gattgacttg gccttggaac
    64921 tgcgtccaga tgtcattgtc atggatattg tcatgcctga gatgaatggg attgacgcga
    64981 ccttagcaat ccttaaagaa tggcctgaag ccaagatttt gattgtgacc tcttatttgg
    65041 acaatgaaaa aatcatgcca gtcttagatg ctggtgccaa aggctatatg ctcaagactt
    65101 ctagtgcaga tgaattgctt catgccgtca gtaaggtagc tgctggcgag ctggccattg
    65161 agcaagaggt tagcaagaag gttgaatacc accgcaatca tatggaactt catgaagaat
    65221 tgactgcgcg tgagcgagat gttctccaac tcatcgccaa gggctacgaa aatcagcgca
    65281 tcgcagatga cctctttatc tctctcaaga cggtcaagac ccacgtgtcc aacattcttg
    65341 ccaaacttga agttagcgat cgtacccagg cggctgtcta tgcctttcag caccatttgg
    65401 tggggcatga ggagttttag atgagtttag cagatttact tgaggagcta gaagcagcaa
    65461 aagactctaa aaaagcaagg cccatggaag cctatatgtg ccatcaattt tcttttctag
    65521 gttgaaagaa ataaactcta taaaaatatt ttccagaagc gaaaaaaaca aagattatcg
    65581 attgggattt tgcagacact tgctgggaaa aggagcctag aaaataccaa tatgtggctg
    65641 ctaactattt gaaagcaatg cagtcttatc taaaggaaac cgatttgcct aagctagagc
    65701 agttagtcgt gacaaaatcc tggtgggaca cggtagatat cctagatcga gtagtaggga
    65761 gtttggtgta taaacatcct gaactagaag aaataatctt aatattcttc gaaaatctct
    65821 tcaaaccacg tcagctctat ctgcaacctc aaaacagtgt tttgagcaat ctgcggctag
    65881 cttcctagtt tgctctttga ttttcattga gtataaaatg gagcctatca gataatatct
    65941 ggctgagacg tgtcgctatt gacaaccagt tgttaagaaa agagaagacc aatactcaat
    66001 taatggaaaa gattctcctt cataacttga accaaacaga attttttatc aataaagcca
    66061 ttggctggac tctgcgagac tactccaaaa cgaatcccac ttgggtaaca tgctttattg
    66121 agaaaaacaa ggaaagaatg gctgaactta gtatcaaaga agcaagtaag tacctctagc
    66181 gtgattgaaa agcgcagtca ttaattgaaa agtttacctg tttatgtgat aatggagggt
    66241 atttaaagaa ggtggtagat ttcttgattc tatagtagat taagaaattt agaatagtac
    66301 gctataatta cattaggagg atacaataat gaagaaaact gtttataaaa aattgggtat
    66361 ttcaattatt gcgagtactt tattggctag ccagttatcg acagtatctg ctttgagtgt
    66421 tatttctagt acgggtgaag aatatgaggt aagtgagaca ctagaaaaag gtccaggatc
    66481 taatgattct tcattatctg agatttcacc aacatatggt tcatactacc aaaagcaatc
    66541 agaagtatta tcggtaatga tgatttgatt aaaattgata atactttaca gtatccgtat
    66601 tcgacttcag ctatggtttt atctaagtat tatggagtag ccgatggaat gaatgtagaa
    66661 gggaggggaa gtgcgaattt tattaaagat aatgtgttaa ttacagcggc tcacagctac
    66721 tacagacatg actatgggaa agaagcggat gatatttatg ttcttccggc tgttagtcca
    66781 agtcaagaac catttggaaa gatcaaagta aaggaagttc gttatttgaa ggaatttaga
    66841 aatttaaatt ctaaggatgc aagggaatat gacttggctt tattaattct agaagagccc
    66901 attggtgcaa aattagggac tttgggtctt cctactagtc aaaaaaattt gacaggaata
    66961 actgtgacta tcacaggcta tccatcatat aattttaaag ttcatcaaat gtatacagat
    67021 aaaaaacaag ttttaagtga tgatggcatg ttcttggatt accaagttga tactttagag
    67081 gggtctagtg gatctacagt ttatgatgct agtcaccgtg tagtaggagt gcatacttta
    67141 ggagatggag ctaatcaaat taacagtgca gttaaattaa atgaacgaaa tttgccattt
    67201 atttattcgg ttcttaaagg ttactctctt gaaggatgga agaaaataaa tggtagttgg
    67261 taccattata gacaacatga taaacaaacg ggttggcagg agataaatga tacttggtat
    67321 tatttagaca gttccggtaa gatgcttaca gattggcaaa aagtaaatgg aaaatggtat
    67381 tatctcaatt caaatggagc aatggttaca ggtagccaaa ctatcgatgg taaagtttat
    67441 aacttcgctt catctggtga gtggatttaa tgttggagga tatataaaat gaagcttttg
    67501 aaaaaaatga tgcaagtcgc actagccaca tttttcttcg gtttgctagg gaccagtaca
    67561 gtatttgcag atgattctga aggatggcag tttgtccaag aaaatggtag aacctactac
    67621 aaaaaggggg atctaaaaga aacctactgg agagtgatag atgggaaata ctattatttt
    67681 gatcctttat ccggagagat ggttgtcggc tggcaatata tacctgctcc acacaagggg
    67741 gttacgattg gtccttctcc aagacaagag attgctttta gaccagattg gttttacttt
    67801 ggtcaagatg gggtactaca agaatttgtt ggcaagcaag tgttagaagc aaaaactgct
    67861 acaaatacca acaaacatca tggggaagaa tatgatagcc cagcagagaa acgagtctat
    67921 tattttgaag atcagcgtag ttatcatact ttaaaaactg gttgggttta tgatgatggg
    67981 gactggtatt atttgcagaa ggatggtggc tttgattctc gcatcaacag attgacggtt
    68041 ggagagctag cacgtggttg ggttaaggat taccctctta cctatgatga agagaagcta
    68101 aaagcagctc catggtacta tctagatcca gcaactggca tcatgcaaac aggttggcaa
    68161 catcttggta ataaatggta ctatctccgt tcatcaggag ctatggcaac tggctggtat
    68221 caagatggtt caacttggta ctatttagat gctgaaaatg gcgatatgaa aactggttgg
    68281 caaaaccttg ggaacaaatg gtactatctc cgttcatcag gagctatggc aactggttgg
    68341 tatcaggaag gttcgacttg gtactatcta aatgcaagta atggagatat gaaaacaggc
    68401 tggttccaag tcaatggtaa ctggtactat gcctatgatt caggtgcttt agctgttaat
    68461 accacagtag gtggttacta cttaaactat aatggtgaat gggttaagta atgaaggcta
    68521 attgtaaact gtgatggata cttaactttg tataataggt ggataaaagt cttcacaatc
    68581 aaaaaacgca tagtatcaag gtttttctgt actgccctca aacagttaga caattaattt
    68641 atccgaagga tttagttctg tattgcacag ggctaagtcc ttttagtttt accttaattc
    68701 gtttattgtt gtagtaatca atatagtcta taatggcttg ttccaattgc ttaagcgact
    68761 gaaacgactt ctcataaccg taaaacattt ccgatttcag aatcccaaag aaggactcca
    68821 tcatactatt gtctgggctg tttcccttac gtgacatgga tgcttgaatt cccttactct
    68881 ctaggaaccg atgataagaa tcgtgttggt attgccagcc ttggtcacta tggagaatcg
    68941 tattcttgta gtgcttctct gtgaatgcct gttccaacat tgtttgtact tgttctaagt
    69001 tgggtgaagt tgaaagatta taggcgataa tttcgctatt aaagccatct aaaactggtg
    69061 ataagtaaag cttttgagta cttgctggaa tggcaaattc tgtcacatct gtgtagcact
    69121 tttccattgt tttagagcct tcaaattggc gttgaatgag attctctgcc ttcttgccaa
    69181 cgtcttttat gagaagaata ttttcgtttc tgtcgcgttt tagcttgtaa attgagtact
    69241 ttcatcaagc cttgaattct tttatgattt accagataac cacgatttct tagttctaaa
    69301 tgaacccggc gataagtata atttcccttg tgttcgataa aaatggattg aatttcagct
    69361 ttaagctctt agtccttatc tggtttatct agctgtttca agtgatagta gtaggtcgaa
    69421 cgagctagtt taatgacttt tagaagaaga gctaacgaaa attcagtcat taattcttga
    69481 acaatttctg tctttcttct ttctcctcct tcaatcggag ttctcttaac ttttttagga
    69541 tggcattctc cgctctcagg tactcatttt ctgcttgaag acgttctaat tctgtcctct
    69601 cttcaggtct cgtttttggc ttacgtccca ttttaggtac tctccctctt gttttctcaa
    69661 caatagtata cccgtttttc ctgtattgtg ctagccagtt aagaagtatc gtacgacttg
    69721 ggagaccgta ttcaagagaa actctatctt tagtccagcc ttcatgtcag actttattac
    69781 tcatttcttg ttttaaatca ggagaatagt aacgattttt tccttttttg acgaactcta
    69841 ttccgtaacg atcaatcaat ttaatcatgt acctaatatt agaattgctt atcccaaatt
    69901 tatttgaaag cttctctaag ctatatcctt gttttctaag ttcatagatc tgaactttat
    69961 catcataagt tagtttcata ataaaaacac cccaaaagtt agattttttc tgtctaactt
    70021 ttggggtgta gttcatgtac acctgatatg atgcgtttta taatttttaa gcctttttgc
    70081 ccagcctcgt caaaagtaat gttttgacac aaaatctgtg acaaaacttt agttttaaag
    70141 gtttttaact ttgtatatac tagttttaag aaaaggagga tgatctaatg gaagaaaaag
    70201 tatcattgaa agtcagggtt caaaaactag ggacatcgct ttcaaatatg gttatgccca
    70261 atattggagc atttattgct tggggagtat tgactgccct ctttatcgct gatggctatc
    70321 tgccaaatga acagttagct actgttgttg gtcctatgtt aacgtattta ttgccaatcc
    70381 tgattggtta cacaggtgga tatatgatcc atggccaacg tggtgccgtt gtaggagcta
    70441 ttgctactgt tggtgcaatc acaggttcta gtgttcctat gtttatcgga gctatggtaa
    70501 tgggcccact gggaggatgg actatcaaga aatttgatga gaagttccaa gaaaaaattc
    70561 gtcccggatt tgaaatgtta gttaataact tctcagctgg tctcgttggt tttgcattat
    70621 tgcttttggc tttctacgca atcggtccag tcgtatcgac tcttactgga gctgttggga
    70681 atggtgttga ggctattgtc aatgctcgcc tccttcctat ggctaatatt atcatcgaac
    70741 cggctaaagt ccttttcctc aataatgccc tcaatcatgg catttttact cctctgggag
    70801 tagaacaggt agctcaagct ggtaagtcaa ttctcttcct attggaagct aatcctggac
    70861 caggcctggg aattctatta gcttatgctg tattcggtaa aggttctgct aaatcttctt
    70921 cttggggggc aatggttatt catttcttcg gagggattca tgaaatttac tttccttatg
    70981 ttatgatgaa gcctactcta tttttagctg ctatggcagg aggtatctct ggaactttta
    71041 cttttcaact cttagacgct ggtcttaaat ctccagcttc accaggttct attattgcga
    71101 ttatggctac ggcgccaaaa ggtgtttggc cccatctaaa tgttcttcta ggtgttttag
    71161 tagcagcagt tgtttctttc cttgtagcag cccttattct tcatgcagac aagtcaactg
    71221 aggattcgct cgaagctgct caggcggcta cccaagcagc taaggctcag tctaaaggtc
    71281 agttagtatc aacttctgtt gatgcagttg tttcgacaga ctcagtggaa aaaatcattt
    71341 tcgcctgcga tgctggtatg ggaagctctg ctatgggagc tagtattctt cgagataagg
    71401 ttaaaaaagc aggtctagag attccagtat ctaatcaggc aatctcaaat ttgcttgata
    71461 caccaaaaac attaattgtt actcaggaag aactgacacc aagagctaaa gacaagagtc
    71521 caagtgctat tcatgtttct gttgataatt tcttagcgtc ccctcgttat gatgaaattg
    71581 tagcttcatt aacaggagct tctccaatag cagaaattga aggagatata ccaacttcag
    71641 caccagtaga tagtcaggaa attgacctta accatattga tgctgtagta gttgcttatg
    71701 gtaaagcaca gggaactgca actatgggct gtgaaacgat tcgggctatc tttagaaaca
    71761 agaatattcg tattccagtt tctactgcca aaatttcaga attaggtgaa tttaattcta
    71821 aaaacataat gattgtaaca actatttctt tacaggcaga agtgcagcaa gcagcaccga
    71881 attctcaatt tcttattgtg gatagtttag taacaacacc agaatatgac aaaatggctg
    71941 ctagaatgta caaatagaac tagaggtttc taaattacga atgctattaa ccaaacgaga
    72001 agaacaatta ttgaaggctt tcctacatgt agggaagctt tcaatgcaag atatgactga
    72061 aatcttacag gtttcatcta gaacaattta tcgaacttta tcagatttga cagatagcat
    72121 ggagcaatat ggaatcgaaa taatgaagca tgggaaatac tatattttga ctggagagtt
    72181 ggatgatttg ccgacagaac ttgaagtgtt agttgagtat agtccccaag aaagacaaga
    72241 gttgattacc tatcgccttc tgactgagag cggttttgtc accaatgaag cattgcaaga
    72301 gtgcacgaaa gtcagtaatg taactattat tcaggatatt tcagatattg ataagcgtct
    72361 tttagacttt gatctgaaaa ttgaacgaca aaaaggttat cggatttctg gtgattcagt
    72421 tggtaagaga agatttttgg ctattttact gacaaactgt atctcagtag cagatttttc
    72481 aaccggtaat tttgggagct ttgatatttt agaagcagat agaactaggc tggccagtca
    72541 gattgttaat aagcaactgt caggttttcc agatatggat gctaggatga agatgttttt
    72601 tgcgatcttg ttatctctta taggtcagga gcaaaacatt gaaaattcac ctaatactag
    72661 taagcaggct ttggaaattt ctcaaaaaat ttttcaaact tactctaagc agactgcaca
    72721 attttatagt attcaggaaa ttatctattt tgcgagcatc ttggatgaat taatcattaa
    72781 acgtcaggac aatccgctct ttacggagaa atttgatggt gaatttttct acaatatttc
    72841 aaatctgatt gatacggttt ccatgtatac caagattgac ttttttaagg acaaggtttt
    72901 attcaatttt cttttccatc atattcggct cagtttaggc gtccctatcc tttttcaggg
    72961 tgaaaatttg ccagaatctg tccagatttt agttgaaagg aataaatttc tttatacagt
    73021 catcagtctt ttagtgaatg atatttttcc gaaatatctt catacagagt atgagtatgg
    73081 catgattgcc ctacatttta tctctagctt aggccgtagt ccagagattt atccagtccg
    73141 tgttttgctt ttaacggatg aacgtcgggt cactagagat ttattagtca gtaaaattaa
    73201 gagtgttgct ccttttgtag agttgataga tattcagtct ctagtagatt accacagtat
    73261 tgatctcagt cagtatgatt atattttatc taccaagccg ctgactaatc aggaaatcga
    73321 tgtaatttct agttttccaa ccgtcaaaga attgcttgaa ttacaggaac gacttcagta
    73381 tgtacaggca catcgtacaa ttgtcgcgcg tgatgctatc gctccagaga aaagttatga
    73441 cttgcaagat tatttaatat ctagtagtca gcttttgagt caattcgagt tggttcaatt
    73501 ggagaataat caatcatttg agcacacggt agaacaaatc atccaatatc agaagaatgt
    73561 gagtgacaga gattacctaa caagaaaatt gttatctcac ttccagaata gtcctatggc
    73621 tattcctaat actggtctgg tgcttttaca tagtcagtct agcaaagtaa caacaaatag
    73681 ttttactatg tttgaactca aactacctat ctccgcattg tcaatgaaac gagaggaaga
    73741 agaggtcaaa aggtgtctgc taatgctaat gtctaaagaa gctagcgagg aagcgagaga
    73801 tttaatgaca gctatcagtc agtcgattat tgaaaatcat ctttatacag agatttacaa
    73861 gacgggaaat caatccatta tttatcagat gctaaatact atttttaacg aaaaaattaa
    73921 gaaattggag aactaatatg aaacttgaaa aacatttgat taagcttaat aaacaatttt
    73981 ctaacaagga ggaagctatt tgttattgtg ggcaagttct ttatgagggt ggatatgtta
    74041 atgaagacta tattgaagcc atgattgagc gagataaaga gctatctgtt tacatgggta
    74101 actttatcgc cataccgcat ggaacagatg cagcaaaaaa tgatgtcctc aagtctggta
    74161 ttacagtcgt tcaagtccct agaggggttg attttgggaa tgtatctaac cctcaagtgg
    74221 caacggttct ttttggtatt gctggtattg gtaatgaaca cttagaaatt attcagaaaa
    74281 tttctatctt ctgtgcagat gtagataatg ttcttaaact agcagatgct cagtcaaaag
    74341 aggaagtatt gcgcttattt gatgctgttg aataattgaa tttcgtcatt tgtcatctag
    74401 tatatatgtc cctcaaatag gaaaaggaga aattgaatga aacattctgt tcattttggt
    74461 gccggtaata tcggtcgtgg ttttataggt gaaattctat ttaaaaatga tttccatatt
    74521 gattttgtgg atgtcaataa tcagataatt catgctctaa atgaaaaggg caagtatgaa
    74581 attgaaattg cacagaaagg acagtctcgt atagaagtaa ctaatgtggc tggaattaat
    74641 agcaaagaac atcctgagca agtcattgaa gcgattcaaa agacggatat tattactact
    74701 gcaatcggac ctaatatact cccttttatc gctgaacttc tagccaaagg aatcgaagct
    74761 cgccgagttg caggaaatac acaggcattg gatgttatgg cctgtgaaaa tatgattggc
    74821 gggtctcaat ttctttatca agaagtcaag aaatatttaa gtccggaagg tttgacattt
    74881 gctgataact acataggttt tccaaatgct gcagtagaca ggattgttcc aacacaaagt
    74941 cacgaagatt ccctttttgt tatggtcgag ccctttaatg aatgggtcgt ggaaaccaag
    75001 cgtcttaaaa atccagattt acgtctagaa gatgtgcatt atgaagaaga tttagaaccc
    75061 tttattgagc gaaaactttt ttcagtcaat tctggacatg caacttcagc ttacattggt
    75121 gcgcattatg gtgccaagac aattttggaa gctcttcaaa atcctaatat caaatctcgg
    75181 attgaatctg tattagctga aattcggagt ctcttgattg ccaaatggaa ctttgataaa
    75241 aaagaattgg agaattatca caaagtcatt atagaacgat tcgaaaaccc tttcatagtg
    75301 gacgaggtta gtcgcgtagc tcgtactcca atccgaaaat taggctataa tgaacgattc
    75361 atccggccga tacgtgaatt gaaagaactc agtttgtcat ataaaaacct acttaaaaca
    75421 gttggctatg cctttgacta tcgcgatgta aatgatgaag aaagtattcg attaggtgaa
    75481 ttgttggcta aacaatcagt caaagatgtt gttatacaag ttacaggttt agacgaccaa
    75541 gaattgattg agcaaattgt agagtatatt taatcttttt cgaaaatctc ttcaaatcag
    75601 gttagcatcc atctgcaacc tcaaaacagt attttgagct gacttcgtca gttctatcta
    75661 caacctcaaa gcagtgcttt gagctgactc cgtcagtctt atctgcaacc tcaaaacact
    75721 gtttgagtta tctgcggtaa tctttctagc ttgtctttga tttttgttgt tatttataag
    75781 gtaaaagaag ctggacaaaa agtcttcaaa atcggaaaaa ggcagcctat cgggtgttca
    75841 aaaatcttga taggatgtcc tttattatgg aaagtcttat tggattttct cctcagattg
    75901 agtttttgat cagctttatg agataggttt tgctagagat gtagcccatc atgttatttt
    75961 tatggacagt gggaaaattg ttgaaaaaaa taatgcccat caattcttta gtcgtccaag
    76021 agaagaacga accaagcaat tttggaacga attctttcga atgtgatcta tatagtaaaa
    76081 tgaaa
//
LOCUS       DBEJJV010000005        76059 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.005, whole genome shotgun sequence.
ACCESSION   DBEJJV010000005 DBEJJV010000000
VERSION     DBEJJV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 76059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76059
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.005"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            145..6846
                     /gene="bgaA"
                     /locus_tag="ACL3GT_000353"
     CDS             145..6846
                     /gene="bgaA"
                     /locus_tag="ACL3GT_000353"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000515226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adhesin/beta-galactosidase BgaA"
                     /protein_id="HGR0516076.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWHF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNNFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SSQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFLYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFVQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKNLTVEWEEVPAEN
                     LIKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7094..7540)
                     /locus_tag="ACL3GT_000354"
     CDS             complement(7094..7540)
                     /locus_tag="ACL3GT_000354"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0516077.1"
                     /translation="MFDKEQKRGYKQSAKNLANWHYNDKEDSYIHPDGWCYRFHHIKY
                     QKTQTDFQQEIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQDRQIFAQRKI
                     DVEPVFGQIKACLGYKRCNLRGKRQVRIDMGLVLMANNLLKHSEMK"
     gene            complement(7705..7950)
                     /locus_tag="ACL3GT_000355"
     CDS             complement(7705..7950)
                     /locus_tag="ACL3GT_000355"
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0516078.1"
                     /translation="MHIHYNTNQTTLPLEISSFLPQDHLVFTIEKVVNTLEERHFYTS
                     YHAFGRPSYHPKMLVSTLLFAYSQGIFSGRKIEKWKS"
     gene            complement(8161..8520)
                     /locus_tag="ACL3GT_000356"
     CDS             complement(8161..8520)
                     /locus_tag="ACL3GT_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HGR0516079.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            8612..9568
                     /locus_tag="ACL3GT_000357"
                     /pseudo
     CDS             8612..9568
                     /locus_tag="ACL3GT_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9552..10109
                     /locus_tag="ACL3GT_000358"
     CDS             9552..10109
                     /locus_tag="ACL3GT_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0516080.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10102..10356
                     /locus_tag="ACL3GT_000359"
     CDS             10102..10356
                     /locus_tag="ACL3GT_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516081.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10368..12422
                     /locus_tag="ACL3GT_000360"
     CDS             10368..12422
                     /locus_tag="ACL3GT_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HGR0516082.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLSLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12601..13461
                     /locus_tag="ACL3GT_000361"
     CDS             12601..13461
                     /locus_tag="ACL3GT_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HGR0516083.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPCFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLRDPVFKKD"
     gene            13672..14382
                     /gene="ccdA2"
                     /locus_tag="ACL3GT_000362"
     CDS             13672..14382
                     /gene="ccdA2"
                     /locus_tag="ACL3GT_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0516084.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14402..14968
                     /locus_tag="ACL3GT_000363"
     CDS             14402..14968
                     /locus_tag="ACL3GT_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HGR0516085.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14979..16091
                     /gene="msrB"
                     /locus_tag="ACL3GT_000364"
     CDS             14979..16091
                     /gene="msrB"
                     /locus_tag="ACL3GT_000364"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0516086.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISEDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            16359..17096
                     /locus_tag="ACL3GT_000365"
     CDS             16359..17096
                     /locus_tag="ACL3GT_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HGR0516087.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            17093..18784
                     /locus_tag="ACL3GT_000366"
     CDS             17093..18784
                     /locus_tag="ACL3GT_000366"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0516088.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYHMKIDSRPQKGTKVEIYINRIETS"
     gene            18900..19463
                     /locus_tag="ACL3GT_000367"
     CDS             18900..19463
                     /locus_tag="ACL3GT_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HGR0516089.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGHIG
                     KESSQEIGELIVETILDILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKT"
     gene            19485..25154
                     /locus_tag="ACL3GT_000368"
     CDS             19485..25154
                     /locus_tag="ACL3GT_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0516090.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGYLSGDILKTLGLDTV
                     LEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEALKEEAPKTEESPKEEPKS
                     EIKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPTEEPKV
                     EQVGEPVEPSEDEQAPTAPVEPEKQPEAPEEEKAVEETPKPEDKIKGIGTKEPVDKSE
                     LNNQIDKASSVSPTDYSTASYNDLGPVLETAKGVYASEPVKQPEVNSETNKLKTAIDA
                     LNVDKTELNNTIADAKTKVKEHYSDRSWQNLQTGVTEAEKVAANTDAKQSEVNSETAS
                     LKTAISRLNTDKVELENQLKIAQGKTETDFSMESWTVLSTAKNKAQEVKDNGTATQEQ
                     INEAEKSLKTALADLSVDKTALGSAIDTATKKNKENYTNQTWAELETALTAAKSVNTN
                     ESKQSDVNEAAEKLTATMEKLVELSEKPRLTLSIEKRDIDRKATVTYTLENPANTQIK
                     SITATLKKGEEVVKDFVLTEENLKTNHLTALFEKLDYYKEYTLSTDMVYNRGNDDETE
                     SISEELIQLNLKKLELKDIQTVSLMKFENGQESQVTHLSDKPTDLSKLYLKVTSSTSK
                     DAVLAVSSIEEEIIENKKIFKIHADTPELVVRKKDGSLSKGFDYYMERVIPHDGDIYY
                     DFKDLISAMTSNPTGTFILGRDISSRNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIF
                     DLEYPLFDTIKSGVVKDIDFKHVNMVFPDSNQGDNVATIARVIKDKTKIENVNVEGYL
                     EGRDHVAGLVNNLEGNSEIENVSFTGKIKSKGGNSITAGIAGRNILSRVKRAYVNADI
                     EVHRSSNSSMLVAVNGINADASGGWGTWGRLTESVAKGTLETKQGGQAGGASSTVWPY
                     GAIDNVVSYAKVTKGKELFGSDGDLNYDWFMKKISNIFGVQGISSGDSGSDSKFTRIS
                     EEEANQKVASYNITAPNLMSDSSLLVDRLNESWKNTDQFESIQDYQAQNQLIYQNLTK
                     FTPYYNKEFIVHEGNALTPEQEILKTKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGS
                     QKRYKVTSTGKFSITNLPEYQVEDLNVVYTSEHIVHPLDSSLINNLVEELKKVELYTE
                     STYQVLGIDKDNANKLNRTKRLFLDESLDAVKTQLPTFVKTMFENEWLHINGESSGAV
                     AALRQKIMDNKTAILLALTYINRYYDVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRL
                     GSSGENRLKGSENAETFKQLFASETKQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDY
                     IQFEERPSLVEEIKDAKYRVYDNLTAPYYQGYILPLLTLKNTHLAILSNYSTMTFVSR
                     EKRPNWKNEDFDKWVKYVATAHRNHVDTWYKILPDNIKGKMVKENVTAVWEGLSIPGS
                     EWVDQNAVDRKGRDYAPAREFFNLVGGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSE
                     YGISVFTHELTHVNDTWIYLGGYGRRENMGPEAYAQGLFQSPVPGQPGWGALGLNMAF
                     ERKNDGDLIYNASPTQFENRKELDSYMKNYNDTLMMVDYLEGDAVISKGKEAITKWFK
                     KVEPKVVSQTAQYDTVRQLTAEEKEKLSVSSVDDLVDQGLMSDRAVGNNTYNPADFET
                     SYIAIDYMTGIYGGGKNSVGSPGALMFKHNTFRMWGYYGFEEGVLGYASNKFKQASRD
                     EGHAGLSDNFIISKISKGEFLTMEAFKKGYFKKVVEELKTKGIRPVTINQKTYSTFEE
                     LQEGFKQAVERDLKKNQLDERETRNFKFQVFRQLLQQTDSFKTSIFR"
     gene            25215..26936
                     /gene="pabB"
                     /locus_tag="ACL3GT_000369"
     CDS             25215..26936
                     /gene="pabB"
                     /locus_tag="ACL3GT_000369"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HGR0516091.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFHSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGKISQKQLMFEE
                     QHLERLRKASRYFAYPFDPEILRQKIEAECQTCDANQDYRLRISLSKSGEIEFSRQIL
                     TPLSPSFCQAKLCLQEANLNQSFTYFKTTYRPHLSIEEQEKIYHNGKGELLETSIGNL
                     VLKIDGKLYTPPIRLGILPGIYHQYLLETGQVEEKVLTLADFAQAEAIYGCNAVRGLY
                     ELQVIGL"
     gene            27467..28582
                     /locus_tag="ACL3GT_000370"
     CDS             27467..28582
                     /locus_tag="ACL3GT_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0516092.1"
                     /translation="MSKGDFIDPKTQFKHQYRGESPVFRIRNRKYVELGTTDKKLDER
                     RDNSVYKDGVVEHKVNLSLTSYQGGNGVTAIFSTDSVNSNLLNSFGEKAKKVLIRSKL
                     INVKTGEVIDETFSPKVSLTSKILKSGSTAVFYFIDLTDGEYKYVAYESQQYTDPQTT
                     LTHQYRGESPIFSIKDGKFSGLVSASKPDENPKPTPKPDEKPKPSAPQQEKTKPTVQS
                     GWVGSSYYQNGKKVTSKWIFDKKYNSYFYLDASGNYVQNAWVGNYYLKSGGYMAKSEW
                     IYDKNYGSYYYLTSEGSYARNTWSGNYYLKSNGKMAKSEWVYDSNYKSYYYLTSEGSY
                     ARNTWVGNYYLKSNGKMAVNERTPDGYRVDGSGKWVK"
     gene            28669..29588
                     /locus_tag="ACL3GT_000371"
                     /pseudo
     CDS             28669..29588
                     /locus_tag="ACL3GT_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811638.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Ltp family lipoprotein"
     gene            29723..30682
                     /locus_tag="ACL3GT_000372"
     CDS             29723..30682
                     /locus_tag="ACL3GT_000372"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HGR0516093.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            30779..31618
                     /locus_tag="ACL3GT_000373"
     CDS             30779..31618
                     /locus_tag="ACL3GT_000373"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HGR0516094.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(31666..31836)
                     /locus_tag="ACL3GT_000374"
     CDS             complement(31666..31836)
                     /locus_tag="ACL3GT_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HGR0516095.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            31957..32841
                     /gene="miaA"
                     /locus_tag="ACL3GT_000375"
     CDS             31957..32841
                     /gene="miaA"
                     /locus_tag="ACL3GT_000375"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HGR0516096.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            32834..34072
                     /gene="hflX"
                     /locus_tag="ACL3GT_000376"
     CDS             32834..34072
                     /gene="hflX"
                     /locus_tag="ACL3GT_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HGR0516097.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            34065..34688
                     /locus_tag="ACL3GT_000377"
     CDS             34065..34688
                     /locus_tag="ACL3GT_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HGR0516098.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTDQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFFENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVISLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            34703..35632
                     /gene="rnz"
                     /locus_tag="ACL3GT_000378"
     CDS             34703..35632
                     /gene="rnz"
                     /locus_tag="ACL3GT_000378"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HGR0516099.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTGASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            35653..36408
                     /locus_tag="ACL3GT_000379"
     CDS             35653..36408
                     /locus_tag="ACL3GT_000379"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0516100.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(36462..37370)
                     /locus_tag="ACL3GT_000380"
     CDS             complement(36462..37370)
                     /locus_tag="ACL3GT_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0516101.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            37434..37703
                     /locus_tag="ACL3GT_000381"
     CDS             37434..37703
                     /locus_tag="ACL3GT_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HGR0516102.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            37703..38083
                     /locus_tag="ACL3GT_000382"
     CDS             37703..38083
                     /locus_tag="ACL3GT_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0516103.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            38172..38399
                     /locus_tag="ACL3GT_000383"
                     /pseudo
     CDS             38172..38399
                     /locus_tag="ACL3GT_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(38439..39164)
                     /locus_tag="ACL3GT_000384"
     CDS             complement(38439..39164)
                     /locus_tag="ACL3GT_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HGR0516104.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGKILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTILKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            39326..41167
                     /gene="typA"
                     /locus_tag="ACL3GT_000385"
     CDS             39326..41167
                     /gene="typA"
                     /locus_tag="ACL3GT_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HGR0516105.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            41187..41441
                     /locus_tag="ACL3GT_000386"
     CDS             41187..41441
                     /locus_tag="ACL3GT_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HGR0516106.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLLLAYFSVRDITLMPVKKSKRR"
     gene            41806..42105
                     /locus_tag="ACL3GT_000387"
                     /pseudo
     CDS             41806..42105
                     /locus_tag="ACL3GT_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
     gene            42188..44209
                     /locus_tag="ACL3GT_000388"
                     /pseudo
     CDS             42188..44209
                     /locus_tag="ACL3GT_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            44211..44852
                     /locus_tag="ACL3GT_000389"
     CDS             44211..44852
                     /locus_tag="ACL3GT_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516107.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            44956..46308
                     /gene="murD"
                     /locus_tag="ACL3GT_000390"
     CDS             44956..46308
                     /gene="murD"
                     /locus_tag="ACL3GT_000390"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HGR0516108.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLVKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            46312..47370
                     /locus_tag="ACL3GT_000391"
     CDS             46312..47370
                     /locus_tag="ACL3GT_000391"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0051991 -
                     UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-
                     glutamyl-meso-2,
                     6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol
                     4-beta-N-acetylglucosaminlytransferase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0007049 - cell cycle [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0030259 - lipid glycosylation [Evidence
                     IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HGR0516109.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLLELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            47380..48579
                     /gene="divIB"
                     /locus_tag="ACL3GT_000392"
     CDS             47380..48579
                     /gene="divIB"
                     /locus_tag="ACL3GT_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HGR0516110.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEDDKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDLDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            48812..49513
                     /gene="pyrF"
                     /locus_tag="ACL3GT_000393"
     CDS             48812..49513
                     /gene="pyrF"
                     /locus_tag="ACL3GT_000393"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HGR0516111.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHTIKDEWTQDWN"
     gene            49547..50179
                     /gene="pyrE"
                     /locus_tag="ACL3GT_000394"
     CDS             49547..50179
                     /gene="pyrE"
                     /locus_tag="ACL3GT_000394"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HGR0516112.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            50640..50762
                     /locus_tag="ACL3GT_000395"
     CDS             50640..50762
                     /locus_tag="ACL3GT_000395"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516113.1"
                     /translation="MYYNGGGDNYIGSGTRLAMAPQFGNHVRIHTSGSWNPDSY"
     gene            50858..51622
                     /locus_tag="ACL3GT_000396"
     CDS             50858..51622
                     /locus_tag="ACL3GT_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516114.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            51622..52374
                     /locus_tag="ACL3GT_000397"
     CDS             51622..52374
                     /locus_tag="ACL3GT_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516115.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            52384..53082
                     /locus_tag="ACL3GT_000398"
     CDS             52384..53082
                     /locus_tag="ACL3GT_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516116.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            53079..53726
                     /locus_tag="ACL3GT_000399"
     CDS             53079..53726
                     /locus_tag="ACL3GT_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516117.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(53806..54667)
                     /locus_tag="ACL3GT_000400"
                     /pseudo
     CDS             complement(53806..54667)
                     /locus_tag="ACL3GT_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(54679..55437)
                     /locus_tag="ACL3GT_000401"
     CDS             complement(54679..55437)
                     /locus_tag="ACL3GT_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0516118.1"
                     /translation="MSETILEIKELKKSFGDNPILQGLSLEIKKGEVVVILGPSGCGK
                     STLLRCLNGLESIQGGDIFLDGQSIVENKKNFHLVRQKIGMVFQSYELFPHLDVLQNL
                     ILGPIKTQGRDKKEVTEEALQLLDRVGLLDKQHSFARQLSGGQKQRVAIVRALLMHPE
                     IILFDEVTASLDPEMVREVLELINDLAQEGRTMILVTHEMQFAQAIADRIIFLDQGKI
                     AEEGTAQAFFTNPQTKRAQEFLNVFDFSQFGSYL"
     gene            complement(55438..56115)
                     /locus_tag="ACL3GT_000402"
     CDS             complement(55438..56115)
                     /locus_tag="ACL3GT_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0516119.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(56075..56743)
                     /locus_tag="ACL3GT_000403"
     CDS             complement(56075..56743)
                     /locus_tag="ACL3GT_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0516120.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LSQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGDSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            56969..57103
                     /locus_tag="ACL3GT_000404"
                     /pseudo
     CDS             56969..57103
                     /locus_tag="ACL3GT_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            57243..58733
                     /gene="lysS"
                     /locus_tag="ACL3GT_000405"
     CDS             57243..58733
                     /gene="lysS"
                     /locus_tag="ACL3GT_000405"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HGR0516121.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYTNLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            59358..60494
                     /gene="lctO"
                     /locus_tag="ACL3GT_000406"
     CDS             59358..60494
                     /gene="lctO"
                     /locus_tag="ACL3GT_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HGR0516122.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDKRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGTQTIEDVKHFKLRHNPYNPTFPVDPRDLRLY"
     regulatory      60748..60836
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            61051..61719
                     /locus_tag="ACL3GT_000407"
     CDS             61051..61719
                     /locus_tag="ACL3GT_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HGR0516123.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLIMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            61956..62738
                     /gene="thiM"
                     /locus_tag="ACL3GT_000408"
     CDS             61956..62738
                     /gene="thiM"
                     /locus_tag="ACL3GT_000408"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004417 - hydroxyethylthiazole kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0516124.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPE
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            62740..63369
                     /gene="thiE"
                     /locus_tag="ACL3GT_000409"
     CDS             62740..63369
                     /gene="thiE"
                     /locus_tag="ACL3GT_000409"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0516125.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDNIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      63578..63666
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            63928..64488
                     /locus_tag="ACL3GT_000410"
     CDS             63928..64488
                     /locus_tag="ACL3GT_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0516126.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            64489..65874
                     /locus_tag="ACL3GT_000411"
     CDS             64489..65874
                     /locus_tag="ACL3GT_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0516127.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMESLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMDRTTCEFGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            65876..66526
                     /locus_tag="ACL3GT_000412"
     CDS             65876..66526
                     /locus_tag="ACL3GT_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HGR0516128.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            66537..67229
                     /gene="tenA"
                     /locus_tag="ACL3GT_000413"
     CDS             66537..67229
                     /gene="tenA"
                     /locus_tag="ACL3GT_000413"
                     /EC_number="3.5.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050334 - thiaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HGR0516129.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            67234..67758
                     /gene="thiW"
                     /locus_tag="ACL3GT_000414"
     CDS             67234..67758
                     /gene="thiW"
                     /locus_tag="ACL3GT_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HGR0516130.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            67758..68561
                     /locus_tag="ACL3GT_000415"
     CDS             67758..68561
                     /locus_tag="ACL3GT_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HGR0516131.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRIAASYAAQVCLPMVVDAVGVTASSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            68554..69186
                     /gene="thiE"
                     /locus_tag="ACL3GT_000416"
     CDS             68554..69186
                     /gene="thiE"
                     /locus_tag="ACL3GT_000416"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HGR0516132.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(69396..70187)
                     /gene="thiD"
                     /locus_tag="ACL3GT_000417"
     CDS             complement(69396..70187)
                     /gene="thiD"
                     /locus_tag="ACL3GT_000417"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0516133.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(70271..70369)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            70553..70948
                     /locus_tag="ACL3GT_000418"
     CDS             70553..70948
                     /locus_tag="ACL3GT_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HGR0516134.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            70959..71330
                     /locus_tag="ACL3GT_000419"
     CDS             70959..71330
                     /locus_tag="ACL3GT_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HGR0516135.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFSFACGMNMMHGKMIVE"
     gene            71340..73583
                     /locus_tag="ACL3GT_000420"
     CDS             71340..73583
                     /locus_tag="ACL3GT_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0516136.1"
                     /translation="MTEIVKASLENGIQKIRIQAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSICTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKKNAKLAISQLKKRGLGTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            73790..75565
                     /gene="spxB"
                     /locus_tag="ACL3GT_000421"
     CDS             73790..75565
                     /gene="spxB"
                     /locus_tag="ACL3GT_000421"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HGR0516137.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            75676..76023
                     /locus_tag="ACL3GT_000422"
     CDS             75676..76023
                     /locus_tag="ACL3GT_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0516138.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
BASE COUNT        23186 a        13750 c        16744 g        22379 t
ORIGIN      
        1 catatctacg gcaaggcgac gctgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgctgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caagcttcaa gtcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa atgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggca ctttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgcagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 aatttcgatc atgaatctcc tgcacaaaat gaaggtggac aactcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc tatccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac gtggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggcaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcatcagc aacccgtaca
     2101 cgaggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt cagattatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt gttcttgaat ggaaaatctc ttggtcttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccaggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc acccttactg ctcactctga tctcttgaaa
     3061 tctagtcaag tcactgtctt tactggtaag aaagaaggac aagaaaagac tgttttgggg
     3121 acagaggtgc caaaagtaca gaccattatt ggagaggcac ctgaaatgcc taccactgtt
     3181 ccgtttctat acagtgatgg tagtcgtgca gaacgtcctg taacctggtc ttcagtagat
     3241 gtgagcaagc ctggtattgt aacggtgaaa ggtatggctg acggacgaga agtagaagct
     3301 cgtgtagaag tgattgctct taaatcagag ctaccagttg tgaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcctatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaagca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ttgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcaag catatttgtt cagcctaaag atggtggccc tcttcaaacc
     3781 tatgcaattc aattcctaga agaagcacca aaaattgctc acttgagctt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgat aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagtgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtcca
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaagg tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag actcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgtcc tattcggaga ttcaggtatt
     4741 ttgagcaaac gttcagttga taacttaagc gttggcttcc atgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtga gagcagacaa caaactagga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa gcaaggacaa
     5101 acaagaatcc aagttgacgg taaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttacg gcagtcacag caagtgttag caacaatggc
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccgg ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaaaac
     5461 ctgacagttg aatgggaaga agttccagcg gaaaatctga taaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgct
     5821 caagccaaac ttcacttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagcagat aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac caagtgaatt gcctcaagaa agcacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgaga agacagttgc tgctgtacaa
     6421 gaagatcttc caaaactcga atttgttgaa aaagatttgg cctacaagac agttgagaaa
     6481 aaagattcaa cactgtatct aggtgaaact cgtgtagaac aagaaggaaa aactggtaaa
     6541 gaacgtatct ttacagcgat taatcctgat ggaagtaagg aagaaaaact ccgtgaagtg
     6601 gtagaagctc cgacagaccg catcgtcttg gttggaacca aaccagtagc tcaagaagct
     6661 aaaaaaccac aagtgtcaga aaaagcagat acaaaaccaa ttgattcaag tgaagctagt
     6721 caaactaata aagcccagtt accaaataca ggtagtgcgg caagccaagc agcagtagca
     6781 gcaggtttag ctcttctagg tttgagtgca ggattagtag ttactaaagg taaaaaagaa
     6841 gactagaaat tttgatacct tctttatcat taaagaccaa agaaaaactc ttgtcctaaa
     6901 tagaagataa agagtctgga acaaaatagt tctcaaccac aaaaaagcta gatatttcca
     6961 attgcggaac tctagctttt taattttgag tcgttctctt attgtatagt agattgaaac
     7021 tagagtagta cacttctact tctaaaacat tgttagaaat cgatttgact gtccttatcg
     7081 atttgtcctg ttcttatttc atttcactat gttttaggag gttattggcc ataagtacca
     7141 atcccatgtc aattctcact tgacgcttgc ctctcagatt acatctcttg taacccaaac
     7201 aagcctttat ctgcccaaag acaggttcta catcaatctt gcgttgagcg aaaatctgtc
     7261 tatcttgggg agataaaagc gcctgacatt ctttagcttt caagttttga tagcgttcgt
     7321 tcatatacaa tcccttttga ggggctgatt caggttcatc agcgtagtaa accttgattt
     7381 cctgttgaaa gtctgtctgt gttttctggt acttgatatg gtgaaaacga tagcaccagc
     7441 catcaggatg tatgtagcta tcctccttgt cattatagtg ccaattcgct aagtttttag
     7501 ctgactgttt ataccctctc ttttgttcct tatcaaacat ggcatattta atcagaaggg
     7561 gagtgatttc ttcttgaaaa tagacttgta tctgttcttg aagtttggcg gagaatttct
     7621 ctgtcgtttt cttccacaca aaactatact tgttggcatt ggattcaatc ttagttccgt
     7681 caataaacaa acaatctaag gtcactaact cttccatttt tcaatttttc gaccagagaa
     7741 aatcccttgt gaataggcaa atagaagagt agatacaagc attttagggt gataagacgg
     7801 gcgaccaaag gcatgatagg aggtgtagaa gtgacgttcc tccaaggtat tcaccacttt
     7861 ttcaatagta aagacgagat ggtcttgtgg taagaaggaa ctgatttcta gtggtaaagt
     7921 tgtttgattt gtgttatagt gaatatgcat gggatagcct ttctaaatgg tttattaagc
     7981 aattctattt taccaagact atcgtaacca tgcaaaaaag caacggcaaa tccgttgcct
     8041 tttttggata taagagacta ttgtcccaga ctcttttctt tgtataaaat tgtatagtgt
     8101 tattgtctat actattttgt agagaaagca aaaatcccta gaaaatgctt agggattcga
     8161 ctatttcatt aagaacaatt caacaatcat ctctatatac atgataaggg ttaataaaaa
     8221 tcctgtacgc cagaagaatt tgatgaattt aggatagtaa aagctgcgtt tttttaaaag
     8281 gaagaaaaag acgagaataa tggctaggaa cgagagggct agccccagtc tagggaggaa
     8341 attatgggta aaggttttag ctgtaatcaa gtaatactca aataccaaga ctggaaaagc
     8401 caaatccgca aagtttcgtc ctagtttttt taatctaaaa agtttggtta ggataatgca
     8461 gacgactaag gtcagtatca ataataaaat agatgctaat ttcattaaaa tcatacccat
     8521 attgtatcat aaaaaaaggc taatggaaac gagaaacaga ggaatttata ggaaagtcag
     8581 gcttttgaga ttgtgggtga tttttgttat aatgaaagtt ataaaatctt atgatacctt
     8641 gaatgattat tatcgaaaac tctttggaga aaagactttt aaagtcccta ttgatgcggg
     8701 atttgactgt cccaatcgtg atggaactgt ggctcatgga ggctgtactt tttgtacggt
     8761 ttccggttct ggagatgcca ttgtagcccc agatccgcct atccgtgagc aattttataa
     8821 ggaaattgac tttattcatc gtaagtggcc agatgttcag aagtatctgg tttattttca
     8881 aaattttacc aacacccatg aaaaggtgga agttattcga gagcgttatg aacaggctat
     8941 caatgagcca ggtgtggtag gaatcaatat tggaacgcgc ccagactgtt taccagacga
     9001 aaccatcgaa tatttggctg agttatcgga gtgcatgcat gtgacggttg aattgggctt
     9061 gcagactact tatgaagcaa cctctgacct gattaaccgt gcgcattctt atgaattgta
     9121 ggtggaaacg gtcaagcgtt tgagaaagta tccaaaaatt gagattgttt cccatttgat
     9181 caatggtttg cctggtgaaa cccatgagat gatggttgaa aatgtccgcc gttgtgtcac
     9241 ggataacgat attcaaggga ttaaactgca tttgctccat cttatgacaa atactcgtat
     9301 gcaacgagat taccatgagg gacgtttaca attgatgagt caggacgaat atgtcagggt
     9361 catctgtgac caactggaaa ttattcccaa acatatcgtc atccatcgaa ttacaggaga
     9421 tgcgcctagg gatatgctga ttggtcctat gtggagcctc aataaatggg aagtcctcaa
     9481 cagcattgag atggagatga gacgtcgtgg aagtgttcaa ggatgcaagg ctgtaaaaca
     9541 ggagtttgaa aatgaaaaga ccacttgaga tggcacatga ttttttggct gaggtcgtga
     9601 caaaagagga tgtcgtagtg gatgcgacta tgggaaatgg tcatgacacg ctttttttag
     9661 ccaagctagc caagcaagtc tatgcctttg atattcagaa gcaagccttg gaaaagaccc
     9721 aagagcgttt gcatcaggct ggcttgacaa atgcccagtt aatcttgcaa ggccatgaga
     9781 cactggacca gtttgtgaca aaagctaagg cagggatttt taatttgggc tatttgccgt
     9841 cagctgataa gtctgtcatc acccgaccgc agacaacgat tgaggcatta gaaaagctat
     9901 gtggcttact tgtcaaaggt ggacgaattg ctattatgat ttactatggt catgaaggag
     9961 gcgacctcga gagagatgct gtcttggatt ttgtgatcca gttgaaccaa caagagtaca
    10021 cagctgccat ttaccgaact ttaaaccaag tcaacaaccc gccgttttta gtgatgattg
    10081 aaaaattaga gagatacaga catggataaa caatacctac acgaaaagct ggatgccatg
    10141 cgccagaatt ttgttgaatc aacctaccac gaacgagcgg tgggcgtgct agaccaagcg
    10201 catatgagca aaaaaatgct taaaatcaag aaaaaattag ttgctcttga aatggaacgg
    10261 tgccagagaa aaattgagca caaagactgt tccaagattg accaaaaaat caaagagcag
    10321 aaggagatat ttgaatcctg ttgtaaaaaa gattaaggag gacgtgcgtg gaattactga
    10381 tttacctcat cctattttta ctggtcttga ttgtctcaag tacaaccaat aagctcctac
    10441 cctttttgcc tctccctttg gtgcagattc ttttgggaat tgtgattggt ctctttttac
    10501 ccaatactga ctttcacctt aatacggagt tgtttttggc actggttatc ggccccttgc
    10561 ttttccgaga ggctgaagaa gcagatgtta cggctatttt aaaacactgg cgaatcattg
    10621 tttatctcat atttccagtg atttttatct cgaccctgag tttgggtggc ttggcccatc
    10681 ttctttggtt cagccttccc ttggcagctt gcttggctgt tggggcagcc cttggtccta
    10741 cggacttggt ggcctttgcc tctctttcgg agcgttttag ctttcctaag cgcgtgtcca
    10801 atattcttaa gggcgaagga ctcttgaatg atgcttctgg tttggtggct tttcaggtag
    10861 ctttgacagc ttggacaact ggagcttttt ctctggggca agctagcagt tcactcatct
    10921 tttcaatcct aggcggtttt ttaattggat ttttaacagc catgaccaac cgcttcctcc
    10981 ataccttctt gctaagtgtg cgtgcaacgg atattgccag tgaactttta ttagaattga
    11041 gtttgcctct tgtgaccttc tttctggcag aagaagttca tgtttcaggt attattgccg
    11101 tcgtagttgc tggaatttta aaggcaagtc gtttcaagaa aatcacgctc ctcgaagccc
    11161 aagtggatac ggtgaccgag acggtctggc atacagtgac ctttatgctc aacggttctg
    11221 tctttgtgat tttagggatg gagctggaaa tgatagcaga acctatcttg accaatccaa
    11281 tctataatcc tctactttta ttgctatctc ttatcgccct tacctttgtc ctctttgtca
    11341 ttcgttttat tatgatctat ggctattatg cctatagaac ccgacgcctc aagaaaaagc
    11401 taaataagta tatgaaggac atgtttctct tgaccttttc aggtgttaag ggaacggtgt
    11461 cgattgctac gattctcttg ataccaagta atctagaaca ggagtatcct ctcttgcttt
    11521 tccttgttgc aggtgtgacg cttgttagct ttttaacagg tctcttggtc ttgcctcatc
    11581 tttctgatga agaggaagaa agcaaggatt atctcatgca tatcgccatt ttgaatgaag
    11641 taacgctaga gttggaaaaa gagttggaag acaccagaaa taaactttcc ctctatgcgg
    11701 ctattgacaa ttatcatgga cgtattgaaa atctcatttt aagccaagaa aaccaggatg
    11761 atcaagaaga ctgggctgct ttgaaactct tgattcttag tattgaaagt gatggtttgg
    11821 aacaggccta tgaagagggg aatattagca atcgtgctta ccgagtttac caacgttatc
    11881 tgaaaaatat agaacaagga atcaatcgta aacttgcctc aagactgacc tattattttc
    11941 ttgtttcctt gaggatttta cgttttctcc ttcatgaagt ttttactctt ggaaagacct
    12001 tccgtagctg gaaggacaag gagcaaagcc gtctccgtgc tcttgattat gaccaaattg
    12061 cagagctcta tcttgccaat acagagatga ttattgaaag tttggaaaac ctgaagggag
    12121 tctacagacg ctctttgatt agttttatgc aggagtctcg tcttcgagaa acagctatta
    12181 tcagcagtgg tgcctttgtc gaacgggtta tcaatcgtgt caaacccaac aatatcgatg
    12241 aaatgctgag aggctattat ctggagcgca agttgatttt cgaatacgaa gaaaaacgat
    12301 taattacaac taagtatgcc aagaaattac gacaaaatgt aaataactta gagaactatt
    12361 ccttgaagga agctgccaat accctgccgt atgatatggt ggaattggta agaagaaatt
    12421 agttaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgga ttatatatgt
    12481 gactgacttc gtcagtttca tctacaacct caaagcaggg ctttgagcaa cctgcggcta
    12541 gcttcctagt ttgctctttg attttcattg agtataagat tataaatgaa ggagtatgac
    12601 atgaaaaagt ggtggaaaga gctgatagac aagcctttat taaaagcttt tttgcattat
    12661 tatcaagcat cagatagtga gttgaccagt gtcgcagtag cctactattg gttgatttcg
    12721 attttccccc tgcttttggt ggtggtcaat atcctcccct gttttcagat tcctgtggga
    12781 gaatttctgt gctttatgaa agacgttctg cccccaagcc tctatgaagg tgtggaaaaa
    12841 atagccagag aagttttgac gcaaccttca acaggtttat tgagtttttc tgttttatcg
    12901 gcgttatgga gtttttcaaa atctatgaat ttcttgcaaa aagcttttaa caaggcttat
    12961 ggcgtcgaaa agagtcgtgg acttatttcc catcagatgc taagtctcct agtcagtttt
    13021 ggcttgcagc tcctctttgc gtttgccttg tttttgatct tatttggtca gatgattttg
    13081 gctttacttg ctcattattg gacaaaagat ggcattatct atcaggcttt acaagggttg
    13141 gcaggtcctc tgatttacgc cctcctcttt gctatcttgg tcatgcttta ttattttctt
    13201 cccaatatat ctaacaggaa aattagctat accctaccag gcagtgcctt tgttctctta
    13261 gtgattttag gtttactaac tctgttctct agttatctca attactatgt ccatcatttg
    13321 gtggatgtcc gaattttagg ttccgttctt cttgttgtta tgatgttttg gtttatcttg
    13381 attgctaaaa ttgttatcct aggcgcggtt atcaatgcca gtatgcagag tttgagagat
    13441 ccggtcttta aaaaagacta actatttatc cattacaaaa gcgcatagta tcaaaacttt
    13501 atagaacctt gatactatgc gcttttgtgc tttgacagtt ttttgtatag tttttgtcca
    13561 agatttctaa atcatctgat taaattccta ttttccccta tcattgtccc tgttttttcg
    13621 aaaatggaag gagtataata aatctatcaa taaaatgata ggaggaactt tatgggtcat
    13681 attttctttt ttctaagtgt ctttttggca gggattctat ccttcttttc tccttgtatc
    13741 ttacctttgt taccggtcta tacaggagtg ttactagatg ataaggatgg tgctcaggct
    13801 tctagcggca aattttcaat ctcagttact agtttattac gaactctggc ctttatagca
    13861 ggaatttcct ttatatttat tttgttgggc tatggagctg gttttttagg cgatttgctt
    13921 tatgcttctt ggttccaata tcttactggg gcaattatta tccttcttgg tttgcaccaa
    13981 atggagattc tacactttaa ggggctttat aaggaaaaga ggctacaact gcaaggacag
    14041 gggcaaaatg gtaagggcta tagtcaggca tttttattgg gcttgacctt tagttttgct
    14101 tggacgcctt gcgtggggcc ggttctgggg tctgttttgg ccttggcggc ttcaggtggt
    14161 tcaggagctt ggcagggagc tggtctcatg ttggtgtata cgctgggctt ggcgctacca
    14221 ttcttgcttc tagctctgac ctctagttat gttttgaaac atttccgaaa acttcatccc
    14281 tatctcggaa tcctcaaaaa agtgggtggt tttctcatta ttgtgatggg actcttggtt
    14341 ctgtttggaa atgcttcaat tttaagtcaa ttatttgaat aaaatggaaa ggaatatcaa
    14401 tatgaaaaaa tggcaaacat gtgttcttgg agcaggttcg ctcctttgtt tgacggcttg
    14461 ttcaggcaag tccgtgacta gtgaacacca aacgaaagat gaaatgaaga cggagcagac
    14521 agctagtaaa acaagcgcag ctaaagggaa agaggtggct gattttgaat tgatgggagt
    14581 agatggcaag acctaccgtt tatctgatta caagggcaag aaagtctatc tcaaattctg
    14641 ggcttcttgg tgttccatct gtctggctag tcttccagat acggatgaga ttgctaaaga
    14701 agctggtgat gactatgtgg tcttgacagt agtgtcacca ggacataagg gagagcaatc
    14761 tgaagcggac tttaagaatt ggtataaggg attggattat aaaaatctcc cagtcctagt
    14821 tgacccatca ggcaaacttt tggaaactta tggtgtccgt tcttacccaa cccaagcctt
    14881 tatagacaaa gaaggcaagc tggtcaaaac acatccagga ttcatggaaa aagatgcaat
    14941 tttgcaaact ttgaaggaat tagcctagga ggtgtcttat gaatgataag ttaaaaatct
    15001 tcttgttgct aggagtattt tttctagcca taaccggttt ctatgttcta ttgatacgaa
    15061 atgcagggca gacagatgcc tcgcaaattg aaaaggcggc agttagccaa ggaggaaaag
    15121 cagtgaaaaa aacagaaatt agtgaagacg cagacttgca cgaaatttat ctagctggag
    15181 gttgtttctg gggagtggag gaatatttct cacgcgttcc cggggtgacg gatgccgttt
    15241 caggctatgc aaatggtaga ggagaaacaa ccaagtacga attaattaac caaacaggtc
    15301 atgcagaaac cgtccatgtc acctatgatg ccaagcaaat ttctctcaag gaaatcctgc
    15361 ttcactattt ccgcattatc aatccaacca gcaaaaataa acaaggaaat gatgtgggga
    15421 cccagtaccg tactggtgtt tattacacag atgacaagga tttggaagtg attaaccaag
    15481 tctttgatga ggtggctaag aaatacgatc aacctctagc agttgaaaag gaaaacttga
    15541 agaattttgt ggtggctgag gattaccatc aagactatct caagaaaaat ccaaatggtt
    15601 actgccatat caatgttaat caggcggcct atcctgtcat tgatgccagc aaatatccaa
    15661 aaccaagtga tgaggaattg aaaaagaccc tgtcacctga ggagtatgca gttacccagg
    15721 aaaatcaaac agaacgagct ttctcaaacc gttactggga taaatttgaa tccggtatct
    15781 atgtggatat agcaactggg gaacctctct tttcatcaaa agacaaattt gagtctggtt
    15841 gtggctggcc tagttttacc caacccatca gtccagatgt tgtcacctac aaggaagata
    15901 agtcctacaa tatgacgcgt atggaagtgc ggagccgagt aggagattct caccttgggc
    15961 atgtctttac ggatggtcca caggacaagg gcggcttacg ttactgtatc aatagcctct
    16021 ctatccgctt tattcccaaa gaccaaatgg aagaaaaagg ctacgcttat ttactagatt
    16081 atgttgatta atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg
    16141 tagggttact gacttcgtca gttttatcta caacctcaaa gctatacttt gagctgactt
    16201 cgtcagtttt atctacaacc tcaaagcggt actttgagaa acctgtggct atcttcctag
    16261 tttacttttt gatttttatt gagtataaga ggtctttcct aagcagttag aggagaattt
    16321 tgctatactg atactagtaa gtggtaaagg agcagagcat gacctacaca atcttaatcg
    16381 tagaagatga atatctggta agacaaggtt tgactaaact ggtcaatgta gcagcctacg
    16441 atatggaaat catcggtcag gctgaaaatg gaaggcaggc ttgggaattg atccaaaagc
    16501 aggtgccaga tatcatttta accgatatca acatgcctca tctaaatggc atccagttgg
    16561 ccagtctggt acgagaaacc tatcctcagg ttcatttggt ctttttaaca ggttacgatg
    16621 attttgatta tgccttgtct gctgtcaaac taggtgtgga cgactacctg ctcaaaccct
    16681 tttctcgtca ggatattgag gaaatgttgg ggaaaatcaa acaaaaacta gacaaggaag
    16741 agaaagaaga gcagttacaa gatttattga ctaataggtt tgaaggaaac atggcccaga
    16801 aaatccagtc tcatctggct gatagccaat ttagtttaaa gtctttagcc agtgacttag
    16861 gttttagtcc gacctatctg agttccttga ttaagaaaga gttgggcttg ccttttcagg
    16921 attatctggt gagagaacgt gttaaacaag ccaagctctt gcttttaact acagatctga
    16981 agatttatga gatcgcagag aaggttggtt ttgaagatat gaactatttt acccaacgtt
    17041 ttaagcagat tgcaggtgtg acacctcgtc agtttaagaa gggagaagac cgatgaagcg
    17101 ttcttctctt ttagttagaa tggttatttc catctttctg gtctttctca ttctcctagc
    17161 tctggttgga actttctact atcaatcaag ttcttcagcc attgaggcca ccattgaggg
    17221 caacagccaa acgaccatca gccagactag ccactttatt cagtcttata tcaaaaaact
    17281 agaaaccacc tcgactggtt tgacccagca gacggatgtt ctggcctatg ctgagaatcc
    17341 cagtcaagac aaggtcgagg gaatccgaga tttgtttttg accatcttga agtcagataa
    17401 ggacttgaaa actgttgtgc tggtgaccaa atctggtcag gtcatttcta cagatgacag
    17461 tgtgcagatg aaaacttcct ctgatatgat ggctgaggat tggtaccaaa aggccattca
    17521 tcagggagct atgcctgttt tgactccagc tcgtaaatca gatagtcagt gggtcatttc
    17581 tgtcactcaa gaacttgttg atgcaaaggg agccaatctt ggtgtgcttc gtttggatat
    17641 ttcttatgaa actctggaag cctatctcaa tcaactccag ttggggcagc agggctttgc
    17701 cttcattatc aatgaaaacc atgaatttgt ctaccatcct caacacacag tttatagttc
    17761 gtctagcaaa atggaggcta tgaaacccta catcgataca ggtcagggtt atactcctgg
    17821 tcacaaatcc tacgtcagtc aagagaagat tgcaggaact gattggacgg tgcttggcgt
    17881 gtcatcattg gaaaagttag accaggttcg gagtcagctc ttgtggacct tgcttggggc
    17941 cagtgtcaca tctcttcttg tctgtctctg cttagtgtgg ttcagtctta aacgctggat
    18001 tgctcctttg aaggatttga gagaaaccat gttggaaatt gcttctggtg ctcaaaatct
    18061 tcgtgccaag gaagttggtg cctatgaact gagagaagta actcgccaat ttaatgctat
    18121 gttggatcag attgatcagt tgatggtagc tattcgtagc caggaagaaa cgacccgtca
    18181 gtaccaactt caagcccttt cgagccagat taatccacat ttcctctata acactttgga
    18241 caccatcatc tggatggctg aatttcatga tagtcagcga gtggtgcagg tgaccaagtc
    18301 cttggcaacc tatttccgct tggcgctcaa tcaaggcaag gacttgattt gtctctctga
    18361 cgaaatcaat catgtccgcc agtatctctt tatccagaaa caacgctatg gagataagct
    18421 ggaatacgaa attaatgaaa atgttgcctt tgataattta gtcttaccca agctggtcct
    18481 acaacccctt gtagaaaatg ctctttacca tggcattaag gaaaaggaag gtcagggcca
    18541 tattaaactt tctgtccaga aacaggattc gggattggtc atccgtattg aggatgatgg
    18601 cgttggcttc caagatgctg gtgatagtag tcaaagtcaa ctcaaacgtg ggggagttgg
    18661 tcttcaaaat gtcgatcaac ggctcaaact tcattttgga gccaattacc atatgaagat
    18721 tgattctaga ccccaaaaag ggacgaaagt tgaaatatat ataaatagaa tagaaactag
    18781 ctaactccca gtcaattctg ggagttttat gcgtaattgg gcaaactttc taggttgtct
    18841 atcttgctaa aaacaagaaa aaacggtatg atagaagagt gacaacagag gtaacagaga
    18901 tgaacgagac acagattcaa agagaaacac gtcaggtagt ggaagatgtt ttagaaaaga
    18961 ccaatttgaa gcagggggcc ctttttgttt taggtctatc ttctagtgag gtgctaggtg
    19021 gtcatattgg gaaagaatcc agtcaagaga ttggtgagct gatagtggag actatcttgg
    19081 atattctagg tagtagaggt atccatttag cagttcaagg ttgtgagcat gtcaatcggg
    19141 ctctcgttgt tgaacgtcag gtggcagagc agtttggtct ggaaattgtc agtgtccatc
    19201 ctactcttca tgcaggaggt tcggggcagt tggcagcctt taagtttatg caggatccag
    19261 ttgaggttga atttatcaag gctcatgctg gattggatat cggagacact gcaattggca
    19321 tgcatgtcaa gcatgttcag gttccgattc gccctatttt gagagagatt ggtcatgccc
    19381 atgtaacggc actggctagt cgtccaaaat taatcggagg tgcgcgtgcg cactatccgc
    19441 aagatgctat tagaaagacc tgagaatgaa taaaggagat aaaagtgttt aaaaaagacc
    19501 gtttttcaat tcgtaagatt aagggagttg taggctctgt atttcttgga agccttttga
    19561 tggctccttc tgtagtggac gcagccacct atcactatgt aaataaagag attatttcac
    19621 aagaagctaa agatttaatt cagacaggaa agcctgacag gaatgaagtt gtatatggtt
    19681 tggtgtatca aaaagatcag ttgcctcaaa cagggacaga agcatctgtt ttgacagctt
    19741 ttggttatct atcaggtgac atcctcaaaa cgcttggctt ggacactgtt ttagaagaaa
    19801 cctcagcaaa acctggagag gtgactgtag tcgaagttga gactcctcaa tcaacaacaa
    19861 atcaggagca agctaggaca gaaaaccaag tagtagagac agaggaagct ctaaaagaag
    19921 aagcacctaa aacagaagaa agtccaaagg aagaaccaaa atcggagata aaacctactg
    19981 acgacaccct tcctaaagta gaagagggga aagaagattc agcagaacca gctccagttg
    20041 aagaagtagg tggagaagtt gagtcaaaac cagaggaaaa agtagcagtt aagccagaaa
    20101 gtcaaccatc agacaaacca acagaggaac caaaagttga acaagtaggt gaaccagtcg
    20161 agccaagtga agacgaacag gcaccaacgg caccagttga gccagaaaag caaccagaag
    20221 ctcctgaaga agagaaggct gtagaggaaa caccgaaacc agaagataaa ataaagggta
    20281 ttggtactaa agaaccagtt gataaaagtg agttaaataa tcaaattgat aaagctagtt
    20341 cagtttctcc tactgattat tctacagcaa gttacaatga tcttggacct gttttagaaa
    20401 ctgcaaaagg tgtctatgct tcagagcctg taaaacagcc tgaggtaaat agtgagacaa
    20461 ataaacttaa aacggctatt gacgctctaa acgttgataa aactgaatta aacaatacga
    20521 ttgcagatgc aaaaacaaag gtaaaagaac attacagtga tagaagttgg caaaacctcc
    20581 aaactggggt tacagaagct gaaaaagttg cagctaatac agatgctaaa caaagtgaag
    20641 taaattctga gactgcaagt cttaaaacag caatttctag attaaataca gataaagttg
    20701 aactcgaaaa tcaacttaag attgcacagg gaaaaactga aactgatttc agcatggaat
    20761 cttggactgt tttgagtaca gctaaaaata aagctcagga agtaaaagat aacggaacag
    20821 cgacccaaga acaaataaac gaagcagaga aaagtttgaa aacagccctt gctgacttat
    20881 ctgttgacaa aacagctttg ggaagcgcta tcgatacagc tactaagaaa aataaagaga
    20941 attatacaaa tcaaacatgg gcagagttgg aaacagcgct tacagcagca aaatctgtaa
    21001 atactaacga gtctaaacaa agcgacgtta acgaagctgc tgaaaaatta actgcaacta
    21061 tggaaaaatt ggttgaattg tctgaaaagc cacgtttgac tctatctatt gaaaagagag
    21121 acatagatcg aaaagctacg gtcacgtata ctttggaaaa tccagcaaat actcaaataa
    21181 aatcaataac tgcaactctg aaaaaaggag aggaagttgt taaggatttt gttttaacag
    21241 aagaaaatct taaaactaat catttaactg ctttgtttga aaagctagac tactacaaag
    21301 aatacactct atctacggat atggtatata acagaggaaa tgatgatgag acggagagta
    21361 tttcagaaga actaattcag ctgaatctta agaaactaga attgaaagat atccagacag
    21421 tctctctgat gaaatttgaa aatggtcaag aaagtcaggt tacacacttg tctgataaac
    21481 cgaccgattt gagtaaatta tacttaaaag ttacatcatc aacgtctaag gatgctgtgt
    21541 tagccgttag ctctatagaa gaagagatta ttgaaaataa aaaaatcttt aaaattcatg
    21601 cagatacacc agaattagta gttcgtaaga aagatggcag tctttctaag ggatttgact
    21661 attacatgga gagagttatc cctcatgatg gtgatattta ttatgatttt aaagacttga
    21721 tttcagctat gacatctaat cctacaggta cgtttatttt agggagagat atttcctcgc
    21781 gtaatgtaaa accggatgga aatggaaaat cttatatcaa aggtgaattt aaaggaaaac
    21841 tacttggtac aaatgataat gttagacact cgatctttga cttagaatat ccattgtttg
    21901 atactataaa atcaggagtc gtgaaagata ttgatttcaa gcatgtcaat atggtattcc
    21961 cagatagcaa tcaaggagat aacgtagcaa caattgcaag agtaatcaaa gataagacaa
    22021 aaattgagaa tgttaatgtt gaaggttatc tcgagggtcg agatcatgta gctggtttag
    22081 ttaataatct tgaaggtaat tccgaaattg aaaatgtatc ctttacagga aagattaagt
    22141 ctaaaggtgg taattctatt acagcaggta ttgcaggtag aaatatctta tctcgtgtta
    22201 aacgtgccta tgtaaatgca gatatagagg tacatcgatc atctaattct agcatgcttg
    22261 ttgcagtaaa tggaataaac gcagatgcaa gtggtggttg gggaacctgg ggtagactta
    22321 ctgagtcagt tgctaaagga acattagaaa ccaagcaagg agggcaagct ggaggagcct
    22381 cttctacagt ctggccttat ggagcaattg ataatgttgt cagctatgca aaagtgacca
    22441 aagggaaaga attatttgga tcagatggtg atttaaatta tgattggttt atgaaaaaaa
    22501 ttagtaatat ttttggtgtt caaggcatca gctcaggcga ttcgggtagt gattctaaat
    22561 ttacgcgtat ttctgaggaa gaagcaaatc aaaaagttgc ttcttataat attacagctc
    22621 ccaacttgat gagtgactca agtcttttgg tagacagact caatgaaagt tggaaaaata
    22681 ctgatcaatt tgaaagtata caggattatc aagcccaaaa ccaattaatt taccagaact
    22741 tgactaaatt tactccttat tacaataaag aatttattgt tcatgaagga aatgctctca
    22801 ctcctgaaca ggaaatattg aagactaaga aaatcaaatc gattgtaggg ttgaaaggaa
    22861 cagagttcgt tgtagatggc agtgatattg atactatcat gcttcatttt gaggatggta
    22921 gtcagaagcg atataaggta acctctactg gtaagttttc gataactaat ttaccggaat
    22981 atcaggttga agatttaaat gtggtgtata catcagaaca tatagtacat ccactagatt
    23041 cgtcactgat aaataacctt gttgaagaat tgaaaaaagt agaattgtat acagagtcta
    23101 cttaccaagt tctaggtatt gataaagata atgctaacaa attgaataga actaagagat
    23161 tattcttaga tgagtcatta gatgctgtta aaacacaatt gcctaccttt gtaaaaacaa
    23221 tgtttgaaaa tgagtggttg cacatcaatg gagaatctag tggagctgtc gctgctttac
    23281 gacaaaaaat catggataat aagacggcta tattgcttgc tttgacttat atcaatcgtt
    23341 attatgatgt taaattctca gactataata ttaaaaaact gatgctcttt aaaccaactt
    23401 tccatggtga aaagattgat ctattagatc gattaatccg actaggatca tctggagaaa
    23461 atagattaaa aggttcagaa aatgcagaaa cgttcaagca gttatttgct agcgaaacga
    23521 agcagaagga tttggtgact tatttagact acaatcgctc tttgttgact aattatcaaa
    23581 caacagggga atggtttaaa gaaacgacta aggattatat tcaatttgag gaacgtccat
    23641 ccttagtaga ggagattaaa gatgccaaat atcgagttta cgataattta accgcaccgt
    23701 attatcaagg atatatccta cctctcttaa cgttgaagaa tactcattta gcaattttat
    23761 cgaactatag tactatgaca tttgtcagcc gtgaaaaacg ccctaattgg aaaaatgaag
    23821 attttgataa gtgggtgaaa tatgtagcaa ctgctcatag aaaccatgtt gatacttggt
    23881 ataagatttt acctgataat atcaaaggta aaatggttaa agagaatgtt actgctgttt
    23941 gggaaggatt gagcatccca ggaagtgaat gggtagacca gaatgctgta gatagaaaag
    24001 gaagagatta cgccccagct cgagaattct ttaatcttgt aggtggtcct atgggaggtt
    24061 ggtatgctta ccatggttat ggtgcgcatg ctggaggaag aaatcgggtt aattatgagg
    24121 tgtttgatgt attaagtgag tatggtatat cggtctttac tcatgaattg actcacgtta
    24181 atgatacttg gatttactta ggagggtatg gtagacgtga aaatatggga cctgaagctt
    24241 atgctcaggg attattccag tctcctgttc caggtcagcc gggttggggg gcgcttggtc
    24301 tcaatatggc atttgaaaga aaaaatgatg gtgatctaat ttataatgcc tccccaactc
    24361 aatttgaaaa taggaaagag ttagatagtt atatgaaaaa ttataacgat actctcatga
    24421 tggtggacta cttggaagga gatgcagtta tctctaaagg taaagaagct attactaaat
    24481 ggtttaaaaa agttgaacct aaggttgtta gtcaaacagc tcagtatgat acggttcgtc
    24541 agttgactgc tgaagagaaa gaaaaacttt ctgtttctag tgttgatgat ttagttgatc
    24601 aaggattaat gtcagacaga gctgtaggaa ataataccta taatccagct gattttgaaa
    24661 caagttatat tgcgatagat tatatgactg gtatttatgg tggaggaaag aatagtgtag
    24721 gttcaccagg tgccttgatg tttaaacata atactttccg tatgtggggc tactatggtt
    24781 ttgaagaagg tgttctagga tatgcttcta ataaatttaa gcaagcatct agagatgaag
    24841 gtcatgctgg acttagtgat aactttatta tttctaagat ttccaaaggg gaatttttaa
    24901 ctatggaagc atttaaaaag ggatatttta agaaagtagt agaagagtta aaaactaaag
    24961 gtattcgtcc tgttactatc aatcaaaaaa catatagcac ctttgaagaa ttgcaagaag
    25021 gatttaagca ggctgttgaa agagatttga agaaaaatca gttagatgag agggaaacaa
    25081 gaaacttcaa attccaagtt ttcagacaac ttcttcaaca aacagatagc tttaaaactt
    25141 ctatctttag ataatcgaaa tctctcatct gctttgcgga tgagggtttt cttattttat
    25201 gctatactta aagtatgcat agaaaaacag tgattgattt taggactttg ggggagagat
    25261 atacctttac ccagcctatt aaagagttga aaacgagaaa tgtagaagaa gtggcagatt
    25321 tgctggcaca agtggaaagc taccaagagc aaggttatta tgtggtgggg tatgtcagct
    25381 acgaggctgc acctgctttt gaggaaaaat tagcagttca caaggatccc ctactgggag
    25441 agtacctgct ttattttact gttcatgata gcgtagaaac ttcccctatt cctctgactt
    25501 atgaggatat tgatttgccc tcaaattggc aggaagtaac gtctgcagca gactatgaaa
    25561 aggccattgc ccaaattcac catcatttac ggcagggaga tacctatcag gtcaactaca
    25621 ccgtccaact taagcaaaag ttaaatgcca atccttttgc catctacaat cgtatggtgg
    25681 tagagcagga ggcgggctac aatgcctatg tggaacatga cgagatggca gtgatttcca
    25741 tgagcccaga gctctttttt gagcaaaatg atcgcgagtt gacaacacga ccaatgaagg
    25801 ggacgactca gcgtggggta actgaccaag aagatcttga acaggccagt tggttggaac
    25861 aggatcccaa aaatcgctct gaaaatatga tgattgtgga cctcttgcgc aatgatatga
    25921 accgtatttc tgaagttggg agcgagcacg tggagcgtct gtgtcaggta gagcagtatt
    25981 caactgtttg gcagatgact tcgaccatca agagtcagtt gcgagaggat gtggaccttg
    26041 ttgaaatctt ccactcactc tttccttgtg gttccataac gggtgcaccg aaaattgcga
    26101 caatggagat tatcaaggac ttggagcctc aaccgcgtgg agtctactgt ggaacgattg
    26161 gtctcttgct tccaaatgga cgacggattt ttaatgtggc cattcgtacc attcaacttc
    26221 acaaaggtca agccatttat ggagttggcg gagggattac ttgggatagc acttgggaat
    26281 ctgaataccg tgaagttcat caaaaggcag cagttctcta tcgtaaacaa gctcgcttcc
    26341 aattaattac aactggaaaa atcagccaaa aacaactgat gtttgaagaa caacatctgg
    26401 aaaggctgag aaaagctagt cggtattttg cttatccttt tgacccagaa attttgagac
    26461 aaaagattga agcagagtgt cagacttgtg atgctaatca agattaccgc ttgcgaattt
    26521 ctctcagcaa gtctggagag atagaattca gtcgtcaaat cttaacacct cttagtccaa
    26581 gtttttgtca ggccaaactt tgtctgcaag aagcgaattt gaatcaatcc tttacctatt
    26641 ttaaaacgac ttacagaccg catttgagca tagaggaaca agagaagatt taccataatg
    26701 gaaaaggaga acttcttgaa acctctatcg gaaatttggt tctgaaaatc gatgggaaac
    26761 tctacacacc gcctatccga cttggaatct tgccaggaat ttatcaccag tatttactag
    26821 aaacaggaca ggtagaagag aaagtcttga ccttggcaga ttttgcccaa gcagaagcta
    26881 tttacggctg taatgcagtg agaggcttgt atgagttgca agtgatagga ttgtgagttt
    26941 tagctattaa tagtttttaa tatatattaa aatatattgg tgtttacttt tgatgagata
    27001 tcatatttgt gttataatgt aaccgtaaac aatagaaatt taaaggagat ttttgatgaa
    27061 atcaaaaata gttttgggag cttcgctagc gatcgcaaca cttagcttag tatctcttgt
    27121 cgagattgaa ggactctcac cgtttttaat agagaatgtt agcgcaaata ctcattctgc
    27181 aaataaagtt attaatcata aagtaagtat ttacttagaa aatgctgatg aaggtaaagg
    27241 tctaactgta aacttttcaa cagacagtgt tagtccaaat ttatttgatg agttcgaaaa
    27301 aaagagtgga attacaataa ctactatgtt agtgaatgct aagacaggtg aagttgtaga
    27361 aaaaagatta acaccaagcg tttttttacg ttccaatgat ttaaccagtg ggaccatatc
    27421 ttcgtttatt tttagtgaat atcctgatgg agaatataaa tatgttgtgt ctaaaggaga
    27481 ctttatcgat cctaagactc agtttaaaca tcagtataga ggagaatctc cagtttttag
    27541 aatacgtaat cgaaaatatg tggagttggg aacaactgat aaaaaattag atgaaagacg
    27601 tgataatagc gtttataaag atggggttgt tgaacacaag gtaaatttaa gtttaacaag
    27661 ttatcaagga ggtaatggag ttactgcaat tttttcaact gatagtgtta actctaactt
    27721 acttaattct tttggtgaaa aggctaaaaa agttttgatt aggtctaagt taattaatgt
    27781 taagactggc gaggttattg atgaaacgtt ttctccaaaa gtaagtttaa cctctaaaat
    27841 tttgaaaagt ggttctacag cagtatttta ttttatagat ttaactgatg gcgaatataa
    27901 atatgttgcg tatgaaagcc agcaatatac tgatcctcaa acaacattga ctcatcagta
    27961 tagaggagaa tctcctattt ttagtatcaa agatggaaaa ttttctggtt tagtatctgc
    28021 ctcaaaacca gacgaaaacc cgaagccaac gccaaaaccg gatgagaaac caaaaccttc
    28081 agcaccacaa caggagaaaa caaaacctac agttcagtct ggttgggtag gttcatctta
    28141 ttatcaaaat ggtaaaaaag tcactagtaa gtggattttt gataaaaaat ataattcata
    28201 cttctatcta gatgcatcag gaaattatgt tcaaaacgct tgggtaggta actattatct
    28261 caaatcaggc ggatacatgg ctaaaagtga gtggatttat gataagaact atggttcata
    28321 ctactatcta acatcagaag gcagctacgc tcgtaacact tggtcaggca attattattt
    28381 gaagtcaaat ggtaagatgg ctaaaagtga gtgggtatac gatagtaact acaaatcata
    28441 ttactacttg acatcagaag gaagttatgc tcgtaacact tgggtaggca attactatct
    28501 taaatcaaac ggtaaaatgg ctgttaatga acgtacacca gatggttatc gtgtagatgg
    28561 ttcaggtaaa tgggttaaat aagaaactaa aaaataggat aataggtaat atcagatgaa
    28621 taaaaaaaat tattttcatg tgctttagca ttttcaacga ttggaacatt gtcaacgatt
    28681 gataaatcag gagttcttcc tttttcagcg caaacggtgc aggctgacat acaaacgctt
    28741 accccaatgg caaaatatta tattattctt ccgaaggatg cagaaatata taaaacttgg
    28801 agaggtactg tcaatattcc cattattgat gctacaaaaa ctactccaga attatcttat
    28861 ttcaaagaag atcatcgcaa ctatatagct aatgagaata agtctggtgc caattacata
    28921 gagtggaagg gaacagtaga agagtttaaa gaggccatta agaagttgac tgataaaaaa
    28981 tcaactactg caacaccaaa aaaggatgaa aagccaacac caaaaccgga tgagaagcca
    29041 aaaccaacac ctacagttca gtctggttgg gtaggttcat cctattatca agatggtaaa
    29101 aaagtcatta gtaagtggat ttttgataaa aaatataatt catacttcta tctagatgca
    29161 tcaggaaatt atgttcaaaa cgcttgggta ggtaactatt atcttaaatc aggcggatac
    29221 atggctaaag gtgaatgggt ttatgatgcc acctatcaag cttggtatta tttgacatca
    29281 gatggttctt atgcttacag tacatggcaa ggaaattact atctaaaatc ggatggtaaa
    29341 atggctgtca atgaatgggt tgatggtgga cgttattatg ttggcgctga cggagtttgg
    29401 aaggaaggtc aagcaagtac agcttcttct agtaatgata gcaatagtga atattctgct
    29461 gctttaggaa aggcaaaaag ttataattcg ttattccaca tgtcaaaaaa aaacgtatgt
    29521 atagacaatt aacttctgat tttgataaat tttcaaatga tgcagctcaa tatgccattg
    29581 atcattagat gattaacaga tactggtagg cgaaaaaatt ccttataatc catttacgca
    29641 aacctttgca taagtgaatg gattttgata tactagtact gtaagcattt tcaattacta
    29701 cacaatgaaa aaggagaata tgatgagtca aaagattatt gggattgacc ttggtggaac
    29761 ttctatcaaa tttgcaatct taacaacagc aggagaaatc caaggaaaat ggtcaatcaa
    29821 gaccaacatt ttggatgagg gaagtcatat cgttgatgat atgattgagt ctattcaaca
    29881 tcgtttggac ttgcttggat tggcagcagc ggacttccaa ggcattggaa tgggatcacc
    29941 aggtgtggtt gaccgtgaca aagggactgt tatcggtgcc tacaacttga actggaaaac
    30001 ccttcaacca atcaaacaaa agattgaaaa agctttgggc attccatttt tcatcgataa
    30061 tgatgccaac gtagcagctc ttggtgagcg ctggatgggt gctggagata accaaccaga
    30121 cgttgtcttt atgacactcg gtactggtgt tggtggcggt atcgtcgcag aaggcaaatt
    30181 gcttcacggt gttgctggtg cagcaggtga gcttggtcac atcactgttg actttgacca
    30241 gccaatctca tgtacttgcg gtaagaaagg ctgccttgag acagttgctt cagcaacagg
    30301 gattgtcaac ttgactcgtc gctatgccga tgaatacgaa ggcgatgcag ccttgaaacg
    30361 cttgattgat aatggagaag aagtaactgc taagactgtc tttgatctcg caaaagaagg
    30421 agacgacctt gctttgattg tttaccgtaa cttctcacgt tacttgggaa tcgcttgtgc
    30481 taacattggt tcaatcctaa acccatcaac aatcgtcatc ggtggtggtg tgtcagctgc
    30541 gggagaattc cttctacaag gtgttcaaaa agtttacgat gaaaatagtt tcccacaagt
    30601 acgcacatct actaaattag ctcttgcaac tctaggaaat gacgctggag ttatcggagc
    30661 agcatcactt gtattgcaat aagataatga gagaggaaaa tgctaaccta gagttagtaa
    30721 tgttcctctt ttatttttta tgctatacta gttaggacaa tgaatgaggt gagagtaaat
    30781 gacaaaagca gatacgattt ttaaagagaa tattgaatgc attctaaagg aaggtgtttt
    30841 ctcagagcaa gctcgtccta agtacaagga tgggactgtt gctaattcca agtatgtaac
    30901 tggtgccttt tccgagtacg acttatctaa aggagaattt cctatcacaa ccttgcgtcc
    30961 cattgcaatc aaatccgcca tcaaagaagt tctctggatt taccaagacc agtcaaatag
    31021 cttagaagtg cttaatgaca agtacaatgt tcactactgg aatgactggg aagttggaga
    31081 cacgggaacc attggtgagc gctatggtgc cgttgttaag aaacacgaca ttatcaataa
    31141 gcttctcaaa cagttggaaa ccaatccttg gaatcgccgc aatattattt cgctctggga
    31201 ttaccaagct ttcgaagaaa cagatgggct gctcccgtgc gcctttcaga ccatgtttga
    31261 tgtccggcgt gttgatgggg aaatctatct ggatgcgacc ttgacccagc gctccaatga
    31321 tatgctggtg gcccaccaca tcaacgctat gcagtatgtg gctttacaga tgatgattgc
    31381 caaacatttt ggttggaagg ttgggaagtt cttctatttc atcaacaacc tccatatcta
    31441 tgataatcaa tttgaacaag ctcaggaatt gctccgtcgg gagccgtcaa actgccaacc
    31501 acgcttggtt ttaaatgttc ctgatgggac taatttcttt gatatcaaag cagaagattt
    31561 tgagttggtg gattatgacc ctgttaagcc acagttgaag tttgacctag ctatttaaaa
    31621 gaatagaaaa aagaagttga gaataatccc aacttctttt gtttcttaac gtgatacgcg
    31681 gcgacgagct gcttttttac gattttcttc gatgaaagct gctttttgct cttctggttc
    31741 gattactttc tttttaaatg cgtatactgc acctgcaacg gcagcgacag ttcctgcgac
    31801 acctgttaca agacctttag cgaatccttt agccatgagt cttcctcctt tatattctca
    31861 atcagccagc ctcctcaaga ggtcacattt ttctgactga cctttttgtg ttataataat
    31921 agtaacgaaa aaatgggaat ttttcaagga aaaaagatga aaacaaaaat aattgtgatt
    31981 gttggaccga ctgctgttgg aaagacggct ctagctattg aagttgcaaa gcgctttaat
    32041 ggcgaagtgg ttagtggaga tagccagcaa gtctatcgag gacttgatat tgggacggcc
    32101 aaggctagtc cagaagagca ggcagctgtt cctcatcatt taatcgatgt tagagagata
    32161 accgagtctt actcggcttt tgattttgtt tcagaagcta agatgactat tgaggatatt
    32221 cagagccgtg gcaagctagc cattatcgcc ggtgggactg gactttatat ccagagcttg
    32281 ctagaaggtt accacctagg tggggagact cctcatgagg agattttagc ttatcgagct
    32341 agtttggagc catattcaga tgaggaatta gcccatttgg tggagcaagc aggccttgag
    32401 attccccagt ttaatcgtcg tcgtgctatg cgtgccttag aaattgccca ttttggtcag
    32461 gatttggaaa atcaagagat cttgtatgaa ccgctgatta tctgcttgga tgatgaacgt
    32521 agtcaacttt atgagcgtat caaccaccga gtggatttga tgtttgaggc tgggcttttg
    32581 gatgaggcca agtggctgtt tgaccattcc cctaatgtac aggctgctaa aggaattggc
    32641 tataaggaac tctttcctta tttccgtgga gagcagacct ttgaggaagc tcgtgagagt
    32701 cttaaacagg cgacccgtcg ttttgccaag cgtcagctga cctggttccg taatcgcatg
    32761 caggtcacct tttatcagat tggagaatct ggtgtacaag accgcatttt aagccagata
    32821 gaggagtttt tagatgattg aaacggagaa aaaagaggag cgagtcctgc tgattggtgt
    32881 ggaattgcag ggtatggaca gttttgacct ctccatggaa gaattggcta gtttagcgaa
    32941 aacggcaggg gcagtcgttg tagatagcta cagacaaaaa cgtgaaaaat atgattccaa
    33001 gaccttcgtc ggctctggta agttggaaga gattgcgctt atggtggatg cagaagaaat
    33061 cactactgtc atcgtcaaca atcgtctgac cccaaggcag aatgtcaatc tagaggaagt
    33121 tctcggtgtt aaggtcattg accgtatgca attgattttg gatatctttg ccatgcgggc
    33181 tcgaagccat gaagggaagc tccaagtcca cctagcccaa ctcaaatacc tcttgcctcg
    33241 cttggttggt caggggatta tgctcagccg tcaggcaggg ggaattggtt cccgtggtcc
    33301 tggtgaaagc caactggagc tgaaccgtcg tagcgttcgc aatcaaatca cggatatcga
    33361 gcgccagctt aaggtggttg agaaaaatcg tgcgactgtc agagaaaaac gtttggagtc
    33421 tagcactttt aagattggtt tgattggtta tactaatgct gggaaatcaa ctatcatgaa
    33481 catcttgacc agtaagaccc agtatgaagc agatgagctc tttgcgactc tggatgcgac
    33541 aaccaagagt attcatctgg gaggcaatct ccaagtaact ttgacagata ccgttggctt
    33601 tatccaagat ttgccgacag agttggtgtc cagtttcaag tcaaccttgg aagaaagcaa
    33661 gcatgtggac cttctggttc atgttatcga tgctagcaat ccttaccacg aggagcatga
    33721 aaaaacggtt ctctccatca tgaaagacct ggacatggaa gatattcctc acttgacgct
    33781 ttataataaa gcggatttgg tggaggattt cacgcctacc caaacgccat ataccctcat
    33841 ttctgccaag tctgaggaca gtcgtgaaaa cttgcaagca ttattgctag ataagattaa
    33901 ggaaattttt gaagcattta ccctgcgagt gcctttttca aagtcctaca agattcatga
    33961 tttagagagt gttgcaattc tggaagaacg tgattatcag gaagacggcg aagtgattac
    34021 aggctacatt tccgagaaaa ataaatggag gttagaagaa ttttatgact gatattaaaa
    34081 ctttggctct aaagtatgga ggttatacaa gtctggacaa ggtctatctg gatcagcttc
    34141 tagctggtaa aacagatcag gagcagttaa cacttattac acctccgcca agtgttgtta
    34201 atgcctactt tgcagaactc tatcagaaaa agagtcctca ggctgcgacg gattattttg
    34261 cagaactcag tcaggaactg aatctttaca atactgagcc aagtttcacc ctagaaaata
    34321 agccttttat tcggcttaat ctgtctggta aatcctttgg tttttgttat gagagtgacg
    34381 gccttggtcg gattttcttt gaaaatgagg agaaaatctc ggatgacttg ctctttgaaa
    34441 ttgcgcaaat tttcccccat caattagtct ttgaagagtc tggtaagatt tacatgaagc
    34501 ctgtcgagga cgaggaagtt atcagcctag aaagtctcac agctttgact gatttggaaa
    34561 gattggctga tggtcgaaaa cgtctcaaag gctacagcca agaggattta ttgcaagaag
    34621 ctgctgcttt ttctggcaaa cgctatttcc gatcggaaaa ccgcacagcc atgttatata
    34681 ttgattaatt agaaagtatc gaatggatat tcaattttta ggaacggggg ctggtcagcc
    34741 ctctaaagcc cgcaacgttt caagtctcgc cctgaaactt ttggatgaga ttaacgaagt
    34801 ttggctcttt gactgtggag aaggtacgca aaatcgcatt ctggaaacca caattcgacc
    34861 acgtaaggtc agcaaaatct ttattaccca tctgcatgga gaccacattt ttggtttgcc
    34921 aggtttcctt tctagccgtg cctttcaggc caatgaagag cagacagatt tggaaatcta
    34981 cggacctcaa ggaatcaagt catttgtctt aaccagcctt cgtgtgtcag gttctcgtct
    35041 gccctaccgc attcatttcc atgagtttga ccaagattct ctgggtaaaa ttcttgaaac
    35101 cgataaattc actgtgtatg cagaggagct ggaccacact attttctgtg ttggctatcg
    35161 tgtcatgcaa aaggatctag aagggacgct ggatgctgaa aaactcaagg ctgctggtgt
    35221 tccgttcggc ccgctttttg gtaaaatcaa aaacggccag gatcttgttt tggaagacgg
    35281 aactgaaatc aaggcagcag actatatctc agcgccacgt ccaggtaaga ttatcactat
    35341 tttaggagac actcgaaaaa cgggtgccag tgtgcgtctg gctgtcaatg cagatgtcct
    35401 agttcatgag tccacttatg gcaagggtga tgaaaaaatt gctcgtaacc atggtcactc
    35461 aactaatatg caagctgcac aagtagcggt agaagcaggt gccaaacgcc tcctactcaa
    35521 ccatatcagt gcccgtttcc tctcaaaaga tattagcaaa ctcaagaaag acgctgccac
    35581 aatttttgaa aatgtccatg tggtcaaaga cttggaagaa gtggaaatct agcagtcaca
    35641 gaaaggataa gtatgcctac tattctcatt accggagcta gcggtggtct agctcaagaa
    35701 atggtcaaac tcctgcccaa tgaccaactc atcttgcttg gtagaaataa ggaaaaatta
    35761 gcccaactct acggaaatta ttcccatgca gaattgattg aaattgatat taccgacgat
    35821 tcagccctag aagctctggt aactgatctt tatctccgct atggcaagat tgatgtcttg
    35881 attaacaacg ctggttacgg gatttttgag ggatttgacc agattgctga taaagatatt
    35941 caccagatgt ttgaggtcaa tacctttgcc ctgatgaatc tgtctcgtca ccttgcggct
    36001 cgtatgaagg aaagcagcaa agggcatatc atcaacatcg tcagcatggc aggtctaata
    36061 gctactggca agtctagtct ttactcagcg accaagtttg cggctattgg tttttcaaat
    36121 gctctgcgac tcgaacttat gccctatgga gtctatgtga caacagtcaa tccaggtcca
    36181 atccgaacag gatttttcga ccaagccgac ccagatggaa cttatcttaa atcggttgac
    36241 cgcttcctgc tagaaccaga tgcagtggct aaaaagattg tcaagattat aggaaaaaac
    36301 aaacgagaac tcaatctccc gattttgttg aacctagctc ataagtttta taccctcttt
    36361 cctaagctag ctgataagtt ggcaggggaa acttttaatt ataagtaaaa agaaccaatg
    36421 tgcaggttgt tgctagccta catattggtt cttatcattt ctcaactatc aaactgaact
    36481 tcttctagga gatagtctat aaagcgttcg cccatcttag ataggctggt tttctcatgc
    36541 tggatataga ccagctcgat cgggtcatca atatccagtg ggatagaaac gatattgtct
    36601 ccgtttaggt tgctgttcaa aatccctgtc gcaatggtat aaccatccaa accaatcaag
    36661 agattaaaga gggtggcacg gtcactgacc acaatggatt tcttgtggtg ttcttgagaa
    36721 agaatctctt ctgaaaagta gaaggagttg tgcgtccctt ggtcatagct gaggtaaggg
    36781 aaattctcca aatcagacag tttcaccttg tctttctttg ccagagggtt ggtcttgctg
    36841 acaaagatat gtggttgcgc tgtgaagaga tggtgggcta gcaggtgatt gtcatccagc
    36901 atcttggtta aaacatcacg gttgtaactg tttaagaaga ggaccccgac ctcactgcgg
    36961 aagttcttga cgtcgtcgat aatctcccaa gtccgagttt cacgaaggaa gagttcgtat
    37021 ttctccatat cgcttttctt gagcaaagag acaaaggcat tgaccacaaa ggcatagtgt
    37081 tgagacgaaa cgctaaatag ttcgcggtgg gcgacaggat ttttatagcg ttcctccaga
    37141 agctgggtct gctcgacaac ctgacgggca taagagagaa actccatccc atcacgggtc
    37201 aaggtgattc ccttgggatt gcggataaag atctcaatgc ccatttcatt ttccaaatct
    37261 cgcactgcat tggagagact tggctgagtg ataaagagtt gcttggctgc ctcattcatg
    37321 gagccagttt cgacgatttt gataatataa tgtaattgtt gaattctcat gtttttattg
    37381 taccatactt gccttagaat cgctaaagaa gataggaaaa taaggagcat tgtgtgagtc
    37441 tcttcttgaa aaaaacacaa aattttgcta gaatgagtct tatgaaaaca ttctatgatg
    37501 tgcagcaatt cctcaaacga tttggtatta ttgtttacat gggaaaacgc ttatatgata
    37561 ttgaactgat gaagttggaa ctatctcgga tttacgatgc agggttgatg gataaattag
    37621 actatctaga ggcagaagca gttcttcgca gagagcacaa ggtagaattg gattatattg
    37681 agaaaaatgg agaaaagaac taatggttac ttggattttg tgggcactta tactagcaat
    37741 gttggcgtgg atgggcttta actatcttcg tattcgccgt gcggctaaaa ttgtggacaa
    37801 tgaggagttt gaagccttga ttcgtacggg tcaattgatt gatttgcgcg acccagcaga
    37861 attccacaga aaacatatcc ttggtgcacg caatattcct tcaagtcagt tgaaaactag
    37921 tcttgcagcc cttcgtaaag ataaacctgt ccttctctac gagaaccaac gtgcgcaacg
    37981 agttacaaat gcagctcttt acttgaaaaa acaaggtttt tctgagattt atatcctttc
    38041 ttatggcttg gattcttgga aagggaaagt gaagactagc taaccttatt tccaaattag
    38101 tcgaatgata ggatgaagct attgttttat agtataatta atttgtataa aatttaagga
    38161 gttcttagaa cataaaagaa aagaagaaaa atccactttt tgtgggtatc ttgtcgatta
    38221 ttcttggttt gttatttcca attgtaggcc tgattttggg tatcatagga ttggtcttgg
    38281 ctatttcata ccaaaaagag tcataattag actataaaat agaaaagatt cttaatatct
    38341 taggaattgt gatttctgta gttaactgga ttgtagcaat cgccttaatt tttcggtaaa
    38401 taaaagaaaa aagctttagt tttaaagctt tttttgtttt atcgactcat ctctaaatag
    38461 tttttaatga tttgtaactc tttttggttc aaagggcggt agttactttc tgctaaatct
    38521 gggttcaatg tgaagtcccc aaattggatt ctcttgagga tagtcacctt aacaccaacc
    38581 gagaggaaca ttttcttgat ttgatgaaat tttccttctg aaatggtgat agaggcttga
    38641 ctgatggagg gacttgcaga tagaatctct agttttgcgg gtttacagac agtaccatct
    38701 aaaaagacaa ttcccttttg aaaggcttgg atatggtcag gtgttagaag tccattaacc
    38761 tcaacttgat aagtcttatc gacatgatat tggggatgga ggagttggaa gcccaaggga
    38821 ccgttatcgg tcaagaggag gagtcccgtt gtatctcggt ccagtcggcc aacggcatag
    38881 agcttgtcag actggatgtc agatggaagc aggtccatga cggtcggaag ttccttgtct
    38941 ttgttggctg taacgacacc agcaggttta tgaagcataa gataggtgtg ttcatagcct
    39001 tgaatgattc gatcctgaaa aaggagttct tgtagtcctg tatcgatatt ttgagctagg
    39061 gagcgggctg ggcaaccatc gactagaatt ttccctctga ggagtgcttg cttcatggcc
    39121 tttcggctga ttttttcttg ggctaataaa ttatctaaac gcatactgtg cctatcttat
    39181 cataagtcgc ttgctttgaa aaggcttgac gtgaaaagaa aagcggagtg aaaacattta
    39241 cacttgcttg agttatgtta tttatttgaa attatggtat aatcgttcag ttagaaaata
    39301 aattttgaat attatagagg aaatcatgac aaaattaaga gaagatatcc gtaacattgc
    39361 gattatcgcc cacgttgacc acggtaaaac aaccctggtt gacgaattat tgaaacaatc
    39421 agaaacgctt gatgcacgta ctgaattggc agagcgtgct atggactcaa acgatatcga
    39481 aaaagagcgt ggaatcacca tccttgctaa aaatactgcc gttgcttaca acggaactcg
    39541 tatcaacatt atggacacac caggacacgc ggacttcggt ggagaagttg agcgtatcat
    39601 gaaaatggtt gacggtgttg tcttggtcgt agatgcctat gaaggaacca tgccacaaac
    39661 tcgtttcgta ttgaaaaaag ccttggaaca agaccttgtc ccaatcgtgg ttgttaacaa
    39721 aatcgataag ccatcagctc gtccagcaga agtagtggat gaagtcttgg aacttttcat
    39781 cgagcttggt gcagatgacg accagcttga tttcccagtg gtttatgctt cagcgatcaa
    39841 cggaacttct tcattgtcag atgatccagc tgaccaagaa gcgactatgg caccaatctt
    39901 tgacacgatt atcgaccata tcccagctcc agtagataac tcagatgagc ctttgcagtt
    39961 ccaagtgtca cttttggact acaatgactt cgttggacgt atcggtatcg gtcgtgtctt
    40021 ccgtggtaca gttaaggttg gggaccaagt taccctttct aaacttgacg gtacaactaa
    40081 aaacttccgt gttacaaaac tcttcggttt ctttggtttg gaacgtcgtg aaatccaaga
    40141 agccaaagcg ggtgacttga ttgccgtttc aggtatggaa gacatctttg tcggtgaaac
    40201 catcactccg acagatgcag tagaagctct tccaatccta cacatcgatg agccaactct
    40261 tcaaatgact ttcttggtca acaactcacc atttgctggt aaagaaggta aatgggtaac
    40321 ttctcgtaag gtggaagaac gcttgcaggc ggaattgcaa acagacgttt cccttcgtgt
    40381 tgacccaact gattcaccag ataaatggac tgtttcagga cgtggagaat tgcacttgtc
    40441 aatccttatc gaaacaatgc gtcgtgaggg ctatgaactt caagtatctc gtccagaagt
    40501 tatcgtaaaa gaaatcgacg gtgttaaatg tgaaccattt gaacgtgtac aaatcgacac
    40561 tccagaagaa taccaagggt ctgttatcca aagcctttct gaacgtaaag gtgaaatgtt
    40621 ggatatgatt tcaactggta atggtcaaac tcgtttggtc ttccttgttc cagcgcgtgg
    40681 tttgattgga tactcaactg agttcttgtc aatgactcgt ggttacggta tcatgaacca
    40741 taccttcgac caatacttgc cattgattcc aggggaaatt ggtggacgtc accgtggtgc
    40801 ccttgtttct atcgatgctg gtaaggctac aacttactca atcatgtcta tcgaagaacg
    40861 tggtacgatc tttgtcaacc caggtactga ggtttatgaa ggaatgatca tcggtgaaaa
    40921 ctctcgtgaa aatgacttga cagttaacat cacgaaggca aaacaaatga ccaacgttcg
    40981 ttcagctact aaggaccaaa cagctgttat caagacgcct cgtatcttga cacttgaaga
    41041 gtctcttgag ttcttgaacg acgatgagta catggaagta acgcctgagt ctatccgttt
    41101 gcgtaaacaa atccttaaca aagcagagcg tgagaaagct aacaagaaga aaaaatcagc
    41161 tgaataagag ctagaaagag agaaagatgg tctatttagt cctaggaatt ttactgctcc
    41221 tactctatgt atttgcgaca ccagaaagca ttaaagggac agtcaatatc gtcgctatgg
    41281 tatgtatttt agtggcactc ttgattttat tggttctatc ttttctgaaa atttttcaat
    41341 taccaacaga aatattccta gcaatagcca tgttgctcct agcttacttt agtgttagag
    41401 acattacact catgccagtc aaaaaaagta aaagaagata aaaaagagag ttttggctct
    41461 cttttttgct aggaatttta caagattgca atttattttt gagttatcac catctctttt
    41521 gtttggataa tatgaatggg aaaaacttga ataaaattcg ttaatggaat ctattttata
    41581 tttggttagt actggttgca tattattttg aaataaaact actatataat attattcata
    41641 gaggtaatat agtaaaatat ctaaaaaatt cgattttttc cttgacaaca aataataaaa
    41701 atgttattct tatcacataa gaaagcggtt tcaataaaag agagaggagg atttattttg
    41761 ttgcattgtt gctcaaggtg tgattttttt gaaagaaaaa ataaaatgaa aacgaaaaaa
    41821 catagattac ttgctctagc tcttatttca agttttacat tattgggagc tgcatcagct
    41881 gctgtataat atccagatgg aggagtatgg acatatggag aaggttcagg aggtggttag
    41941 gctttttcaa attactatca tggtaaaaaa tatcattatt catccatcgt gagcagatgg
    42001 gatggtcatt ctgataaagg agaagctcct gctggaaaaa cctcctatgc atggatttgg
    42061 actaaatggg gagaacaagt agcattttac tgtgattatg actaatcgtt cattgattta
    42121 aatcgttccc cttgtaagaa attacagggg gaattttgtt tacaaggagt ctaccaagga
    42181 gtctactatg aagaaactat tcatattatt atcaactttt tttctcagct tcttccttgc
    42241 ttggattatt gtcttacgtg cgccacaata tttatatgca agctatgatt ccgtttcttt
    42301 acttcgtgtc aaaaaagata ctcaggaacc gacgcgtgag gtatttgaac aggaattgga
    42361 gaattttgca aactcagaac agagtttaat agctagaaga attgtagagc cgagtaagga
    42421 tgggacgact cactttactt atgcaactta tggtcaggga actttaccaa aagaattcca
    42481 agaagctagc caagaaagtc gtgaacgtag tgatccgcta aatagttatc tccttttgtc
    42541 aggctccttg acgaaagaaa agcttgccga taaattagga gatttgggtt ataaagcaag
    42601 tgctgaccga aagataccgc cctattttct tgcttttcga atattactaa atccccttat
    42661 tttaattagt ttagcaatat ttggcttatc tttctttgct ttagtgatta tcactcggat
    42721 taaggaaatg agagcagcag gtataaaact cttttctggt cagactctct tatccatcat
    42781 ggggcattct ttatctactg atatcaaata gctccttcta tcagccctcc tttccttcct
    42841 aggtggggga gtcgttcttt ttagtcaagg tttgttttat cctatcttgt tagccaccta
    42901 tggttttggg attagtttct atctgttgtt tttattggcg atttcaattt tactaatgct
    42961 tctttatcta atgagtttga gttacaaagc attagttccc gttattaagg ggagattacc
    43021 ccttaaacgc ctgatgattt taaccctatt gtgtcagttg gttgctgtct ttacagtagg
    43081 atacgctgtt aagacaggtt tgacgtctta ccaacgattg aaagaacttg aaatttcaaa
    43141 acaagcatgg caggatagag cagactatta tcaaatttct tttggcttag gtgatagagg
    43201 aaaagataca gaaaatcaga gcaagtggta tgcctttgcc aaggaagcaa tcgaagagga
    43261 acaagctctt tatgtaaagg ataatctgct ccattttgcc aatccacaag gaaaaaatga
    43321 acagggagag acactggata cctatagtcc agatgctaat acgctctatg ttagtcccag
    43381 ttatttggac aaggaaaagg tcgtggtaga tgctgagacc aaacagaagt tagcccatct
    43441 ccaaaaaggt gagtttatcc tcttgctccc agaacatttg cgctctcgag aagcagaact
    43501 taagaaagtt tttgaagaaa gattgagtta ttatggaaaa tctggtgagg aggcaagtgc
    43561 tcctttggat tatgagatga aagcgcacgt tagttatctt tcaatgggag aaaagcggtt
    43621 tgtttataat aacggtgaga atcccgtatc tactcagtat ttgactgatc cgattttagt
    43681 ggtattcacg ccgacttcta caggtgatag ttttatatcc ttatctagtt ggtctatcaa
    43741 tgctggaaaa caactcttta tcaaaggata tgagagtggg ctagaactct tgaagaaagc
    43801 tggaatttat gagcaagtat cctatcttaa agaaggaaga agtgtttatc taactcgtta
    43861 taatgaagtt caaactgaaa cagcaacttt aatcttagga gctattgtgg ggatagctag
    43921 ttccttatta ctattttatt ctgtcaatct tctatatttc gagcaattcc gccgagatat
    43981 cttgattaaa cgaatttcag gtttacgatt ttttgaaaca catgctcagt atatggttag
    44041 ccaatttgcc agttttgtat ttggtgctag tctctttatt ttaagcagtc gagacttggt
    44101 gattggcttg ctcactttat tggtctttct agctagtgca gttttgacgc tttaccgtca
    44161 agcgcagaaa gaatctcgtg tttctatgac aattatgaaa ggaaaatagg atgattgaac
    44221 taaagaatat atctaaaaaa tttggaagcc gtcagctatt ttcagatacg aatcttcatt
    44281 ttgaaggtgg gaaaatttat gccttaatcg gtacaagtgg ctgtggtaag acaacactct
    44341 tgaatatgat tggacgattg gagccatatg acaaagggca aatcatctat gatggcactt
    44401 ctcttaagga catcaagcct tctgttttct ttagagatta cttaggatac ttatttcaag
    44461 attttggctt aattgaaagc caaaccgtca aagagaatct caatctgggt ttagttggta
    44521 aaaagttgaa ggaaaaagag aaaatctctt tgatgaaaca agctctaaac tgtgtaaacc
    44581 tctcttattt ggatttgaag caacctatat ttgagttatc aggaggagaa gcacaacgtg
    44641 ttgcactagc gaagataatt ttaaaggatc cgcctttgat tcttgcagat gaaccaaccg
    44701 cttccttaga ccccaaaaat tctgaggaat tactttccat cctagaatct ttaaaaaatc
    44761 cgaatcggac cattattatt gcgacccaca atcctctgat ttgggagcaa gtggatcagg
    44821 tcattcgagt taccgattta tcacatagat gatatggtaa gattcagtta gaagaaagag
    44881 tcacaaacac actttgtggc ttttttattt ccataaaaat ggtaaaatag taggagtaga
    44941 aatggagttc gagacatgaa agtaatagat caatttaaaa ataagaaagt tcttgtttta
    45001 ggtttggcca agtctggtga atctgcggct cgtttgttgg acaagttagg tgccattgtg
    45061 acagtaaatg atgggaaacc attcgaggac aatccagctg cccaatgttt gctggaagaa
    45121 gggatcaagg tcattacagg tggccatcct ttggaactct tggatgaaga gtttgccctc
    45181 atggtaaaaa atccaggtat cccctacagc aatcccatga ttgaaaaggc tttggccaag
    45241 ggaattccag tcttgactga ggtggaattg gcttatttga tttcagaagc accgattatt
    45301 ggtatcacag gatcgaacgg taagacaacc acaacgacta tgattgggga agttttgact
    45361 gctgctgggc aacatggtct tttatcaggg aatatcggct atcctgccag tcaggttgct
    45421 caaatagcat cagataagga cacgcttgtt atggaacttt cttctttcca actcatgggt
    45481 gttcaagaat tccatccaga gattgcggtt attaccaacc tcatgccaac tcatatcgat
    45541 tatcatggat tatttgagga atatgtagca gccaagtgga atatccagaa caagatgaca
    45601 gcagctgatt tccttgtctt gaactttaat caagacttgg taaaagactt ggcttccaag
    45661 acagaagcca ctgttgtacc attttcaaca cttgaaaagg ttgatggagc ttatctggaa
    45721 gatggtcaac tctacttccg tggtgaagta gtcatggcag cgaatgaaat cggtgttcca
    45781 ggtagccaca atgtggaaaa tgcccttgcg actattgctg tagccaagct tcgtgatgtg
    45841 gacaatcaaa ccatcaagga aactctttca gccttcggtg gtgtcaaaca ccgtctccag
    45901 tttgtggatg acatcaaggg tgttaaattc tataacgaca gtaaatcaac taatatcttg
    45961 gctactcaaa aagccttatc aggatttgac aacagcaagg tcgtcttgat tgcaggtggt
    46021 ttggaccgtg gcaatgagtt tgacgaattg gtgccagaca ttactggact caagaagatg
    46081 gtcatcctgg gtcaatctgc agaacgtgtc aaacgggcag cagacaaggc tggtgtcgct
    46141 tatgtggagg cgacagatat tgcagatgcg acccgcaagg cctatgagct tgcgactcaa
    46201 ggagatgtgg ttcttcttag tcctgccaat gccagctggg atatgtatgc taactttgaa
    46261 gtacgtggcg acctctttat cgacacagta gcggagttaa aagaataaaa tatgaaaaaa
    46321 attgtcttta caggtggggg gacggttgga cacgttaccc tcaatctttt gttaatgccc
    46381 aagttcatcg aagatggttg ggaagtccac tatatcgggg acaagcgtgg tatcgaacac
    46441 caagaaatcc ttaagtcagg tttggatgtc actttccact ccattgcgac tgggaaattg
    46501 cgtcgctatt tctcttggca aaatatgctg gacgtcttca aagttggctg gggaatcgtc
    46561 caatcgctct ttatcatgtt gcgacttcgt ccacagaccc ttttttcaaa ggggggcttt
    46621 gtctcagtac cgcctgttat cgcagcgcgt gtgtcaggag tgcctgtctt tattcacgaa
    46681 tctgacctgt ctatgggctt ggccaataaa atcgcctata aatttgcgac taagatgtat
    46741 tcaacctttg agcaagcttc gagtttgtct aaggttgagc atgtgggagc agtgaccaag
    46801 gtttcagatc aaaaaaatcc agaaccagat gaattggtgg atattcaaac ccactttaat
    46861 cataaattgc cgactgtatt gtttgttggc ggttctgcag gtgctcgtgt ctttaaccaa
    46921 ttggtgacag accataagaa agaactaaca gagcgctaca atattatcaa tctaactgga
    46981 gattctagcc tgaatgagtt gagccaaaat ctttttcgtg ttgactatgt gaccgatctc
    47041 tatcaaccct tgttggaatt ggctgatatt gttgtgacac gaggtggtgc caatacgatt
    47101 tttgagctct tggcgatagc aaaattgcat gtcattgtgc cgcttggtcg tgaagctagt
    47161 cgtggtgacc agattgaaaa tgcagcttac tttgtaaaaa aaggctatgc agaagacctt
    47221 caagaaagcg atttgacctt ggatagtttg gaagagaagc tttctcactt actaagtcac
    47281 aaggaagatt accaagctaa gatgaaagct tctaaggaat tgaaatctct agcagatttt
    47341 tatcaattgt tgaaaaaaga tttatcataa ggaaagtaaa tgtcaaaaga taagaaaaat
    47401 gaggacaaag aaatcctcga agaattgaaa gagttatcag aatggcagaa acgaaaccaa
    47461 gaatatctaa aaaagaaggc tgaagaagaa gcggctctag ctgaggagaa ggaaaaggaa
    47521 agacaagctc ggatgggaga agaatctgag aagtcagagg acaaacagga ccaggagagt
    47581 gaaacagacc aggaagattc agaatcagct aaggaagagt ctgaagaaaa agtagcatcc
    47641 tcagaggatg acaaagagaa agaagagaaa gaagaaccag agtctaaaga gaaggaggaa
    47701 caggataaaa agcttgctaa aaaggctaca aaggaaaaac cagccaaagc aaagattcct
    47761 ggtatccata tcttgcgagc cttcacgatt ttatttccaa gtctgctttt attgattgtc
    47821 tctgcctact tgctcagtcc ttatgcgacc atgaaagata ttcgtgttga gggaacggtg
    47881 caaactacag ctgatgatat tcgacaggct tcaggcattc aggattcgga ttatacgatt
    47941 aaccttctgc tagacaaggc aaaatatgaa aagcagatta agtctaacta ttgggttgaa
    48001 tcagctcaac ttgtctatca atttccaact aagttcacta ttaaggtcaa ggaatatgat
    48061 attgtggcct actatatttc tggtgaaaat cattatccta ttctttccag tggtcagctt
    48121 gagactagtt ctgtgagcct gaacagttta ccagaaactt atttatcagt tctctttaat
    48181 gatagtgaac aaatcaaggt ttttgtctca gaacttgctc aaattagccc agaactcaag
    48241 gcggctatcc aaaaggtgga attagcccca agcaaggtga catccgattt aattcgattg
    48301 actatgaatg atttggacga agtcttggtt ccgctttctg aaatgagcaa gaaactgcct
    48361 tattatagta agattaagcc acaattgtca gaaccgagtg tgattgacat ggaagctgga
    48421 atttacagtt acactgtggc ggataaatta attatggaag ctgaggaaaa agccaaacaa
    48481 gaggctaagg aagctgagaa aaaacaagaa gaagaacaga aaaaacaaga ggaagagagc
    48541 aatcgaaacc aaacgaccca gcgctcatcg cgtcgctagg tttacctttt ctcttatagt
    48601 tctttagtga ccatgttttt acttgacaag tgctagtaga aataatagaa tagtaaaaaa
    48661 cctttaaagc agtccagaga ggcagctaag gttagacggt gaaagggtgg agactaccca
    48721 tttttcgtgg aaccttgctg ttggcaggtt ccttttttcg tggcttctgt tggccagact
    48781 ctctcactag taaaggtaaa aggagaaacc tatgcgagaa catcgtccag tcattgctct
    48841 tgattttcct agttttgagg cggtcaagga atttttagct cttttcccag cagaagaaag
    48901 cctttatctc aaggtaggga tggagcttta ttacgcagcg gggcctgaga ttgtgtccta
    48961 cttaaaaggt ttgggtcata gtgtcttttt ggatctcaaa cttcatgaca ttcctaatac
    49021 agtcaagtca gccatgaagg tcttgtctca gcttggtgtc gatatgacta atgtccatgc
    49081 ggctggtggt gtagagatga tgaaggcggc gcgtgaaggc cttgggagtc aagctaaatt
    49141 gatcgctgta actcagctca catcaacgtc agaagctcag atgcaggagt ttcaaaatat
    49201 ccaaaccagt ctgcaagagt ctgtgattca ctatgccaag aagacagctg aagctggctt
    49261 ggatggtgtt gtttgctcgg ctcaggaagt acaagtcatc aagcaggcta ccaatccaga
    49321 ttttatctgt ctgacaccag ggattcgtcc agctggtgct gcagttggag atcaaaaacg
    49381 agtcatgaca cctgctgatg cctatcaaat cggcagtgac tatatcgtag tgggacgtcc
    49441 cattacccaa gctgaggatc ctgttgcagc ttatcatacc atcaaggatg aatggacaca
    49501 ggactggaat taaagaacta gattagaaaa ataaaaggag aataccatga cacttgctaa
    49561 agatatcgct agccacctct tgaaaatcca agccgtttac ctcaaaccag aggaaccctt
    49621 cacttgggca tctggtatca agtcaccgat ttacactgat aatcgtgtga cactagccta
    49681 tccagaaact cgtaccctaa ttgaaaatgg ttttgtggaa gctatcaaag aagcctttcc
    49741 tgaagtagaa gtgattgcag gaactgcaac agcagggatt ccacacggag ccattattgc
    49801 tgataagatg gacttgcctt ttgcctacat ccgtagcaaa ccaaaagacc acggagctgg
    49861 taatcaaatc gaaggtcgcg tagctcaagg tcaaaaaatg gtagtggttg aagaccttat
    49921 ttcaacgggt ggttcagttc ttgaagctgt agcagcagcc aagcgagaag gagcagatgt
    49981 gcttggagtt gtagcgattt tcagctacca attgccaaaa gcagataaga actttgcaga
    50041 tgctggtgtt aaacttgtga cgctttcaaa ctatagcgag cttatccatc tagcccaaga
    50101 agaaggttac atcacgccag agggccttga tcttctaaaa cgctttaaag aagaccaaga
    50161 aaattggcaa gaaggttagg tcagtaagat aaagagagat gaggctaccg agcctctttt
    50221 atcattttat ttaaaatatg acaatatttt aaataaaatg attgacaacg ctttcttttg
    50281 ttgatataat gaaaatgtaa tatgtatcaa attgatcaat caactatctt gtttatcact
    50341 tcttaggagg acgatgtcat gaaaagaaga aaaatatatt ccttttttgc gtagttacaa
    50401 ttgcatctag tttgtttctc cttacagttt tagctagaca gattggagat tatgatttaa
    50461 cgttgccgcg ttggggttcg gatacaacta gtgagcttga gaaagaaaac gcctctgctg
    50521 gaattaataa taatgacagc actggtggcg gtaaaaggtt aaatacctct attcgtagcg
    50581 cctatagtgg gtcagatatt accccggtat attcattggg gtctggctct aggattgtca
    50641 tgtactataa tggaggtggt gacaattata ttggttctgg tactagatta gctatggcgc
    50701 cacaatttgg aaatcatgta agaattcata cttcaggttc ttggaatcca gattcttatt
    50761 aacttacttg tcagagtaag ccttagagat ggttgattgt gggtgtagca tgaaaaaaga
    50821 atgctacacc ctatttttat tataaggagg agtaaggatg gaatttttca tttgtaatct
    50881 tgtacgagtc gttcaatcac ctcgatttta tatgtcttta tttttgaccc ttctttgcat
    50941 gagtttagga aatttccttg ctttcaatgg tatttataaa attgaaggtt tatcgatttt
    51001 ttttgccgct tcttctattc gaggattttc accgattagc ctagtagctg cacttatctg
    51061 tacactgccc tattctagtc agataataga ggatgctgag agtcattttc taacagcaca
    51121 attgtgtcga atttctaaaa agaagtatct ggctattgtg ggtagtactg taattatttc
    51181 ttcttttcta gtcttttttc tcccctattt attattatta ggaattaatc ttttagtgac
    51241 tccttatcag gaaatttata ttggagatta tagtggtgcc ttaaaagaat tatttgattc
    51301 caatcagttt ctctatagtc ttgtaacgac tctctggtat ggagtttggg gcgctgtgtt
    51361 ctctattttt ggactagcta gtgctttgct agtgaagaaa aaaataggag ctattttcat
    51421 cccagttgcc tatatgatgg ttggtggtat tttttgggct attttagggc tatcttactt
    51481 agaacctgtg acaacattag ctttgggata tcagaaagat atcagtcttt ccttagttag
    51541 tgggcatctt gcttttattt tatttgttag ttgtttggtt gtttatggta cattttttct
    51601 acattcagag gactacgtat aatgaaacaa tttgttcaat tttacaaaaa agatttttta
    51661 tcagtattgg tttattttat attactgcta tcctgtgttt tatctagtac agtatattta
    51721 ttgcgctgtc gccaatattc aatccatcca aatgtattag aatggatctt agttttactt
    51781 caagatatga cgactggagt atattgcttt ccgttcacat atatattgtt ctttttttat
    51841 ttgatgaata actattttaa taggttggag tgtcgcattc gtctgaaatc aattaagcac
    51901 tttaccagtt ttagtttcaa attagcagct cttagtacgg ggatttggac ggcgacttta
    51961 tttttattga tttttctaat tgcatttagt aatggtttta gcttctcttt ggagataaag
    52021 gaggttgatt ttttaagaga attttatggt ataagtattg caaacaatgc tagtttcttt
    52081 ataggatttt ttttctctta tatagcatac tatttctttt tatccttact tactattagc
    52141 agtttttctt ggtttaaaaa atcaaacatg agcttagtat ttctgtttac ttttttattt
    52201 gtagaatcct tattctggat ttatcagttg gacaatggga taattggatt attgccaatt
    52261 tttcagtata tggtaaattc caatccgtat gcattgattt attggcttac attactatct
    52321 atcataattc cattgactgt attttctgtt catagaaact ggaggagagt gtaaaagttg
    52381 gaaatgggaa agttaagtag tcacatgtgg aggttgaatc agataatcta taccaagtac
    52441 ttttggggtt atgttctttt ttggatattg atttgtttag gattatggta ttggttagaa
    52501 ggaaatgata gacttgttat agaaatttta aaagggccta atctgagtca aaactctttt
    52561 ttagtcttat ctatatggtt gcttcattgg tttattattc atacattttt tctagcagtt
    52621 gtatatcgta gaagagcatc cgatttcttt atggaagtga ttcgattttc ttctattaag
    52681 ctctggatta ggtatcagat ttggacctgt tttctttatg gactcatttt aatcatggta
    52741 aaagttctag tgattcaatt tatgttacag ttaccaaact gggatatagg agttttgttt
    52801 atagttgatt ctttgaatgc ttgtgtgtta gtcttgtttt gctttatgtt atacgcacta
    52861 ggagcgaatg tacaaatgaa ctttgcttgc gttagtttct ttttactcat gattgtgttt
    52921 ggtggtctat ttgtaggaaa tcgaactaat tatctatttt atattttgaa tcgagggaat
    52981 ggagatatag gacgagattt atttcttcag ttgctatttt tagtctttct ttttaaaagt
    53041 attttctatt tcactcgtca aaagaggagg tttatagaat gaatgaaata atcatattaa
    53101 aaaatattga gttgaaatta aaaaaaacat gtgtttttca aaaccttaat tttagttgta
    53161 aacaggggga aattatagga attactggtg cgaatggctc agggaaaagt gtattgttta
    53221 aattaatagc tggtttatat agtccgtctt atggagaagt gttaatcaat ggggaaaata
    53281 ttgttcctga gagaaaaatt ccagctaatt tgggagcttt gattgaagaa cctggtttta
    53341 taaattatta tagtggcttt aagaatttac aatatttggc aagcatacga ggagtagttg
    53401 gtaatcagga aatcaatgat acactgaaaa tagttggtct atatgagcaa aaagaccaga
    53461 aagttaaaac ttattcgcta ggtatgagga aaaagctagg gattgctcaa gcaattatgg
    53521 agaatccctc tattctttta ctagatgaac ctatgaatgc cttggataaa tcaagtgtag
    53581 aaaatatgag aacattgttt agaaagctct ctagtgaaaa agggacaaca attttgattg
    53641 ctagtcatag tgaagaggat attcgtatct tatgtgataa agtatatgca atagaagata
    53701 aagtatgtac actgtgttca gattgaacat cttagataga ctcaggatgt tataggtaaa
    53761 atcttaaaaa gggattggag cttaaaatcc agtccctttt aagagttaat ggccaccttc
    53821 aacaaccagg tcatctgctt tagcagcgtc accgtaggtt gggtgaagtg ttttttcata
    53881 ggccttgtgg aagaagtttt ccttgcctaa tttttcaata tctttattga tgaagtctag
    53941 caattcttgg ttgccttttt gaactgctgc cgcaatggta tcgggatcac cgagggaagt
    54001 aattcctact tcaaatcctt tattttcaag cgcccaagct agaacttccg tattgtcagt
    54061 tgaaaaggca tctccacgtc cgtcaagaag agcttggtaa gagtcactgt attggtcgta
    54121 tttttggagt ttgatttctg gatgattctt ttcaaaataa gtctcagcag tcgttccttt
    54181 tgtgacaatt aaggttttac cttcaagttg tttgacgtct gtaatgagac cagtcttagg
    54241 tgatacgaca cccagagaaa ctttcatata tggaagggca aaatcaactt gtttcttacg
    54301 ttcgtcagtt actgtaaagt tagcaagagt aatatctacc ttgtttgaaa tcaagtattc
    54361 cgcacggttg gcagcatcga ctgaaatgta tttaaccttg acaccaaggt ctttagctag
    54421 ttggttccct agttcaatat cgtagccttg gtaagaacca tcattgtcaa cgtagccaaa
    54481 cggtttttta tctccaaaca cggcgattcg cagttcaccg cctttttttg atttcatcga
    54541 tagtgcgagc tttggcagtt gtttttccag aggatgaacc agcgtttcca cctgagctac
    54601 aagcagtgat aaagataagg gcaaaggcaa gtgctaaaac agttaagagt ggtttgaata
    54661 gtttcataag aatctccttt atagatatga gccaaattgg ctaaagtcaa agacgtttaa
    54721 aaattcctgg gctcgtttgg tttgcggatt ggtaaagaag gcttgagctg ttccttcttc
    54781 agcgattttc ccttggtcga ggaagataat ccggtcagca atggcttggg caaactgcat
    54841 ttcgtgggtt actaaaatca tggtacggcc ttcttgggcc aaatcattga taagttccag
    54901 cacctcacgc accatttctg gatccagcga agcagtcacc tcgtcaaaaa ggatgatttc
    54961 tggatgcatt aggagggcac ggacaattgc aacacgttgc ttctgtccac cagataattg
    55021 acgggcaaag ctatgttgtt tatccagcaa accgacacga tctagtaatt gcaaagcttc
    55081 ttccgttact tctttcttgt cccttccttg agttttgata gggcctagga tgaggttttg
    55141 taagacatcc agatggggaa agagttcata actttgaaag accatgccaa tcttttggcg
    55201 aactaggtga aaattttttt tattttcaac gatagactga ccatccagaa aaatatctcc
    55261 accttgaata ctttctaagc cgttgaggca acgaaggagg gtacttttcc cacaaccaga
    55321 tggccctagg atgacaacaa cttccccttt tttgatttct agagaaagtc cttggaggat
    55381 gggattgtct ccgaaggatt tttttagttc cttgatttct aagatagttt cagacattta
    55441 gtttctccaa tgtttttcta agtgagtgga tagtttggaa atagggtagc aaactgcgaa
    55501 atataagact agaatggttc cataaatcca aaatgaagca gttgggatgg tcaggcgatt
    55561 gctatcgatg atttgttgtc caactttggt cacttccaca accccaatca aaacaactaa
    55621 tgaagtggtt ttaatcatcc gagtgacaag attgatagcc tgcggtagca gtcttctcaa
    55681 gacttgtggg atgatgatgt ggtagtaaag ttgaacatta gtcaagccga gtgcctgtcc
    55741 actttcaaac tgatgtttag ggagagaagt gatagctcca cgtaccaagt ctcccatttc
    55801 agctgttccc cagagggtaa aaacgataat agctgaagtc tcacctgaga tattgatatt
    55861 aaagtttcga gccaagccaa agtaaacgat gaagagtagc accagctggg gcatgatacg
    55921 gataaattcc agatacaatc gtgttaaaaa tcgtatgatt ctagaatggg aggtcatgat
    55981 gattcccatg actgttccga acatcatgga taagaggaca gacaggatgg atatcccaat
    56041 cgtaacgccc aatccctgta agattctcag gagattattt ccttgaaaga gtacttggat
    56101 tcccgaatcc tgcatggcgg agcctccttt ctatccagct aaagaccagt gagatgggta
    56161 gcagcatgat cagataagca actaccaaca tagctagcgc aatgtctgtc tcatagtaga
    56221 gaccaatcaa atccttggcg acgtacatga ggtcggccaa agccactgct gagaaaacag
    56281 aggtttcctt gataaggaaa atgacattgg cactaaagga ggggagtgcc accgctgttg
    56341 cttgcggaag aaccacatag taaaagacct gtagaggtgt cagaccaata gcgaggccaa
    56401 tctcctgctg ggtttgactg atggcttcca gcccgcttcg gaaagattct gccatatagg
    56461 agtctcctaa aaagacaagc ccaagcgttg cacagacttc tgaagatagg acaatcccga
    56521 ttcggggaag accgaagtag agaaagaaga gttgaatcaa aaggggcgta ttacgtgaca
    56581 attcaatgta ggctgtcgct acttgcgaca aaacaaggat tcgataatgt cggatgatac
    56641 taacgattaa accgagcaga aaggatccca aaattcccca aactgcaata tgcaaggtca
    56701 gaaagaatgc cttttgatat agtggtagat attgttcaac aatggatcaa tccaaaaata
    56761 gaacctccca tctagaaata atacagttat tgtagcactt aaaatcttct ttggataata
    56821 tctatttttt attgccgtta taaggatttt tatcatagac ataaaatttc tgaaatttcc
    56881 aaacaaaata ttttaaaagt tttgaaaaag agttaagata tttttgtaat acacaaagta
    56941 aacgcttact tattaaggag gacattttat gtcatacaaa acaagcaatg cagaaggtca
    57001 tgtagatttc atcaatacct atgatttgga gccaatggcg caacaagtta ttcctaaagc
    57061 agcatttggc tatatcgcta gtggggcggg agatactttc acttctttcc agtgatttta
    57121 gcgtcaggtt ctttttagtt tttaaagatt atccgtgaat ttcttgctta tttatgataa
    57181 aatgggagta tcgcaaaaaa tgactcatcg tattcaattt tgagtaaaac taggaggatc
    57241 ccatgtctac agaacatatg gaagaactaa atgaccagca gatcgttcgc cgtgaaaaaa
    57301 tggctgcgct ccgcgaacaa ggaatcgatc ctttcggaaa acgttttgaa cgtactgcaa
    57361 attcacaaga attaaaagat aaatatacca acctcgataa agaacaatta cacgataaaa
    57421 acgaaacagc tactatcgca ggacgcttgg taaccaaacg tggtaaagga aaagttggtt
    57481 ttgcccacct tcaagaccgc gaaggccaga ttcagatcta cgttcgtaag gatgctgtcg
    57541 gtgaagaaaa ctacgaaatc ttcaaaaaag cagaccttgg tgacttcctt ggtgtcgaag
    57601 gtgaagtgat gcgtacggat atgggagaac tctctatcaa ggcaacccac atcacacact
    57661 tgtctaaggc tcttcgtcct cttcctgaga aattccatgg tttgacagac gttgaaacaa
    57721 tttaccgtaa acgttacctt gacttgattt ctaatcgtga aagctttgaa cgctttgtca
    57781 ctcgttcaaa aatcatctct gaaatccgtc gttaccttga ccaaaaagga ttccttgaag
    57841 tggaaacacc tgttcttcat aatgaagccg gtggtgctgc tgcccgtcca tttatcaccc
    57901 accacaatgc ccaaaacatt gacatggtgc ttcgtatcgc gactgagctt cacttaaaac
    57961 gccttatcgt gggtggtatg gaacgtgtct atgaaattgg ccgtatcttc cgtaacgaag
    58021 gaatggacgc tactcataac cctgagttca cttctatcga agtttaccaa gcttatgcag
    58081 acttccaaga catcatggac ttgactgaag gcattatcca acacgctgct aaatcagtca
    58141 aaggtgatgg cccagtcaac taccaaggta ctgaaatcaa gattaacgaa ccatttaagc
    58201 gtgttcatat ggtggatgct atcagagaaa ttactggtgt cgatttctgg caagacatga
    58261 ctttggaaga agctaaagct atcgctgctg agaagaaagt tccagttgag aaacactaca
    58321 ctgaggttgg tcacatcatc aatgccttct ttgaagagtt tgttgaagaa actttaatcc
    58381 aaccaacctt tgtctatgga catccagtag ctgtatctcc actcgctaag aaaaatcctg
    58441 aagaccaacg ctttactgac cgtttcgagc tctttatcat gactaaggag tacggtaatg
    58501 cctttactga gttgaacgac ccaatcgacc aacttagccg ttttgaagcc caagctaaag
    58561 ccaaagaact tggtgatgat gaagcgacag gaatcgacta tgactacatt gaagctcttg
    58621 aatacggtat gccaccaaca ggtggtttgg gaatcggtat cgaccgtctc tgcatgctcc
    58681 tcactgatac aacaactatc cgtgatgtat tgctcttccc aacaatgaaa taaattctta
    58741 tcctctggct cttaccaggg gattttttga ttcaaaaaga gactgaattt aaggagaaaa
    58801 tgaagtgtag tatattgaag ttgaaatagt acactttgat ttctaagaca ttgttagaaa
    58861 ttggtttaaa ttccctaagc aatttgtgca tgttttattt cattttacga tagtacgctg
    58921 aaactgttca aaaagtacta gaaattgact tggattcccc aattgatttg ttcagattca
    58981 ctataaataa aaaattaata agtgggatag gaagttagcg tcaactagga tagtatcttg
    59041 cttaaacagt atatatggga ctgatataag tccataggtc ctattagagg atgttctggt
    59101 gtcttattca cttgtttttt tatagtatta gtagatagaa tccgcaaata aaaaagtagt
    59161 tcaaatgcct ggcagcaaaa aatctcaacg attcacttaa tatagactaa ggtttagagt
    59221 ttaaggaaag tagggctagt atattgtatg aaaaaataag atggttttta agcaaaactc
    59281 ttgaaaatga ttgaaaaaag agttattata gttgtgtagt aaaaagcaaa cgcttactta
    59341 atcaaggagg gcattttatg tcatacaaaa caagcaatgc agaaggtcat gtagacttca
    59401 tcaataccta tgatttggag ccaatggcgc aacaagttat tcctaaagca gcatttggct
    59461 atatcgctag tggggcggaa gatactttca ctttaagaga gaatatccgc gcctttaacc
    59521 acaaactcat cgttcctcat acactttgcg atgttgaaaa tccaagtaca gagattgaat
    59581 ttgcaggtga aaaactatct tcaccaatca ttatggcgcc tgttgcggcc cataaattag
    59641 cgaatgaaca gggggaagtg gcgactgcgc gtggtgtgca tgagtttggt tctctttata
    59701 caaccagttc ttactctact gttgaccttc cagagatttc tgaagccctt caagggacac
    59761 cccattggtt ccaattttac tttagtaagg atgacggtat caaccgccac atcatggatc
    59821 gtgtgaaggc tgaaggttat aaagcgattg tcttgacggc agatgctact gtagggggga
    59881 atcgtgaagt ggataagcgt aatggttttg tcttcccagt tggcatgccg attgttgaag
    59941 aatacctgcc agaaggtgct ggtaaatcaa tggactttgt ttacaaatca gctaaacaac
    60001 gcttgtctcc acgtgatgta gaatttatcg ctgaatactc aggacttcct gtgtatgtca
    60061 agggaccaca atgccgtgag gacgttgaac gttcgcttgc tgcaggagct tctggtatct
    60121 gggtaaccaa ccacggtggt cgtcaaatcg acggtggacc agctgccttt gactcgcttc
    60181 aagaagtggc agaagcagtt gataaacgtg tgccaattgt ctttgactct ggtgttcgtc
    60241 gtggtcaaca tgtctttaaa gccttggctt caggagcaga cttggtagct attggtcgcc
    60301 cggttatcta tggcttggct ctcggcggta gtgttggtgt gcgtcaagtc tttgaacact
    60361 tgaatgcgga attgaagaca gttatgcagt tgtctggaac tcagactatt gaagatgtta
    60421 aacacttcaa actccgtcac aacccataca acccaacttt cccagttgac cctcgtgact
    60481 taagattgta ttgataaaag agattgcctc cactgaatgt ggaggttttt cttcgtgtat
    60541 tggaagaata aatcgctatc gaaaaccata gtaaaatgga ataaaaacag gacaaatcaa
    60601 tcaggacagt taaatcgatt tttaacaatg ttttagaagt agatgtgtac tattctagtt
    60661 tcaatctact atatataaag atatttttcg gtcaaatatc ttgctagggc tttcattttt
    60721 tgctatactg gttcagtaat taaataatag agacatttgg ggtgctttaa gctgagatga
    60781 tacccattga acctgataca gttaagactg gcgaagggaa atgtgaaacg ttttttcgta
    60841 tgacgaaatg aacgatctaa tcttgtaagt caactctaat tcttgattgt aattggagtt
    60901 ttttgtttat ataaactgga taggcttgtt tagttagctc tctgcaaatg ctctcgatgt
    60961 gctttaaaag gatcaagtgg aattacgatt ttgcttgata tttcttggtg ttttattaat
    61021 tactaacaag taaagagagg agaagtaaat atggaaacac aagactatgc atttcagcca
    61081 ggtttgactg ttggagaatt attaaaaagc agtcagaagg attggcaggc tgcaatcaat
    61141 catcgttttg ttaaggaact ttttgcgggg acaattgaga ataaggtctt aaaggactat
    61201 ctgattcaag attatcactt ctttgatgcc ttcttatcca tgctgggtgc ctgcgtagct
    61261 cacgcagata aacttgaatc caagcttcgt tttgccaagc aactaggctt tcttgaagca
    61321 gatgaagatg gttatttcca aaaggctttt aaagagttaa aagtagcaga gaatgactat
    61381 ctagaagtga ctttgcaccc tgtaacaaaa gcctttcagg atctaatgta ttcggcagtg
    61441 gcttcatcag actatgccca tcttttgatt atgctggtca ttgcagaagg tctctattta
    61501 gactggggtt ctaaagattt ggctttacct gaagtctata ttcattcgga atggatcaat
    61561 ctccacagag gtcctttctt tgcagagtgg gttcaatttc tggttgacga actcaatcgt
    61621 gtcggtaaaa atcgagaaga tttgacagaa cttcagcaac gctggaatca agcagtcgct
    61681 ttagaattag ctttttttga tattggttac gatgtctaga gaaggctcat gatatttaca
    61741 aatttgatga ggtaagactc ttcgaaaatc tcttcaaacc acgtcagttc tatccacaac
    61801 ctcaaaacag tgttttgagc aacctgcggt tagcctccta gtttgctctt tgattttcat
    61861 tgagtataaa tcattcaatg taaatgaaaa aaattctcaa ctaaagataa atcgaaatta
    61921 gtagatcgta taaagtgaaa aggaaggatt tcaatatgac aagtttaaaa ttattaaaag
    61981 aaaaagcacc tttggtcatt tgcatcacca atgatgtagt aaaaaatttc acagcaaatg
    62041 gattagtagc actgggcgcc tcaccagcca tgagtgagtt tccagaagat ttagaggact
    62101 tattaaagta tgctggtggt ttattaataa acataggaac attgacagat gaaaattgga
    62161 aattatacca agctgctctg aaaattgcag agaaatataa tgtcccagca gttttagatc
    62221 ctgtagcctg tggagcagga gaatatagaa aaaaagtagc agatgattta atcaacaatt
    62281 acaaactagc tgcgattagg gggaatgctg gagagattgc ctctttagta ggaatagatg
    62341 tggcatctaa aggagtagat agtgcgggag tagataatat tgacgagatt gctctagcag
    62401 caaatgagaa gttcaatatt ccaatagtag taacaggtga agtggatgct attgcggtaa
    62461 atggagaagt ggtaacgatt cataatggta gtgccatgat gccaaaagtt attggaactg
    62521 gatgtttatt aggagctgta gtagcaagtt ttatcggact ggaaaaaggt caagaattaa
    62581 aatcattaga aacagcaatg ttagtttaca atatcgctgg agaaatggca gaaaaacgtc
    62641 caaatggaca tcttcctggg acatttaaag ttgaatttat aaatgcctta tacgagatta
    62701 cagatgaaga tgtaaaggaa ttcaaaagag tgaagtaaga tgtttcataa agaattacta
    62761 aaactatatt ttatttgtgg aacgactact tgccaaggaa aaaatctata tacagtcgtt
    62821 gaggaagcct taaaaggtgg tataacctta tttcaatttc gagaaaaagg tgagggtgct
    62881 ttagaaggct tagaaaaact tgagctagct atccaaatta aagaactttg taaaaaatac
    62941 aatgttccat ttatcgttaa tgacgatata gatttagcaa tggaaattga cgccgatggc
    63001 gtacatgtag gtcaagataa tattggtgtt gatgaaatta gaaaattgat gccagataaa
    63061 ataattggtc tttctataag aaacgaagaa gaatttcaac aatcaaaagt tgaatatgta
    63121 gattatgtag gtgttgggcc tgtatttgat acccagtcaa aagatgatgc tggtggtgct
    63181 ataggttatg aaggtcttga attgatgaga aaactattgc cacaaatgcc tttagttgca
    63241 attggtggga tacagacgaa acatattaaa gacattataa agaccaatat ggatggcgtt
    63301 tcaatcattt cggcaatatc gtatgcaaaa aatatagaaa aaactgttcg ggaaatgagt
    63361 gaacaataga tatctatcct tggattctaa gtaagtagga ttttcctttt ttaaaaagct
    63421 atgtccagat tcagcttgaa tggctaattc atcaaacagg tcatttgttt tttgcaaaag
    63481 aaagatctgc tgtctttgtg agtgcaaggc tgtatttcca gttcaatttc ttgaactagt
    63541 ataaaatgtg tgttataata atcacataat taaataataa agacatttgg ggtgctttag
    63601 gctgagatga tacccattga acctgataca gttaagactg gcgaagggaa atgtgaaatg
    63661 tttttttcgt atgtcgaaaa gaactgtcta atcttgtaag ctgaactcta attcgtatct
    63721 gtaattagag ttttttcttt tacgaaactg gatgaagatg atatagtaga ttgaaataag
    63781 atgcgaacaa atcaattaga aaattcaaat taatttctag aaatatttta gcattcttgt
    63841 gtactgttct aaattcagtc tgctatacaa agtatttagg tcggtcttct tgagtgcccc
    63901 acttttcttt aaaaaaagga gttttttatg ttgaaaaaat ggcagttaaa agatgttatc
    63961 ttgcttgctt tcttgtctat cttttttggt ggggttttcg ttggttcagg atatgtgtat
    64021 aatattctca gtctactctt aacacctctt ggtttgcagg cctttgccaa tgaaatcctc
    64081 ttcggtctct ggtgtatggc tgcgcccatt gctgccatct ttgttccgag agtcggaagt
    64141 gcaacgattg gagaagtgct agctgcgctt gctgaagtcc tttatggtag ccaatttggt
    64201 ctaggagctc ttttgtctgg cttggttcaa ggtttgggaa gtgaatttgg ttttatcgta
    64261 actaagaatc gctatgaaag ttggctctct ctaactgcta atagtattgg gattacgctt
    64321 gttagctttg tctatgaata cattaagtta ggttactacg ccttttccct tccgtttgtc
    64381 ctttccttac ttgtggtacg ttttatttct gtttatttct tctgtaccat cttggttcgt
    64441 gccattgtca aactctatca tcagtttgca actggaggaa aagcatagat gggtctggaa
    64501 ctacgagcga ttcagtcccc aatcttctct gagccgtttg attttacttt tcatgcgcaa
    64561 gcctttacct tgttagttgg gagtagtggg tctggaaaat ccagcctctt tcaaatgatt
    64621 gcccaagtca gttctcttcc ctatagtggt caagtcctga tagatgggag cgaggtcagt
    64681 caactttcta tcatcgcacg tgtccagaag gttggcattc tctttcaaaa tcccaatcat
    64741 caatttacca tggagagctt gtttgaggag ctgattttca ccttggagaa tatcggctat
    64801 caccttcagg aaattgattc taaaatagca gaggttgtcc agcaatgtcg ttgcgaggca
    64861 atcttacacc gtcccattca tcacctatca ggtggggaaa agcaaaaagc agcgctggct
    64921 gtcctctttg ccatgaatcc tagggtctat ctcttggatg aaccttttgc ttccattgac
    64981 cgcaagagca gaatcgagat attggagatt ctaaaagagt tggctcttga tggaaagaca
    65041 gttattttgt gcgaccatga tttatctgac tataaagcct atatcgacca tatggttgag
    65101 ctaagagacg gaaaactaag ggaagtgttt caaatccctt cctatgagat gacacaggtt
    65161 gcttcaaagg aagttgcttc tagcccggaa ctattccata tggatagaac gacttgtgag
    65221 tttggaaatc gccccctctt ttcaattgct gatttcacat tctatcaagg gatttcctgt
    65281 atcctgggtg acaatggtgt cgggaaatca accctctttc ggtctattct tcaatttcaa
    65341 aagtataagg ggcgcattgc atggaagggt tcggtcctga aaaagaaaaa gagtttgtat
    65401 cgtgatctga ctggtgttgt tcaggaagct gagaagcagt ttatccgagt cagtctgcga
    65461 gaggagcttc aattagatgg acctgattct gaaagaaatc agcggatttt tcaagcttta
    65521 cgatattttg atttggagca ggcagtcgat aagagtccct atcaattaag tggtggtcag
    65581 caaaaaattc ttcagctcct gaccatcttg accagtaagg cttccgtgat cttgctagat
    65641 gaaccttttg caggtttgga tgatagagcc tgccattatt tttgcaagtg gattgtggag
    65701 gagaggaatc aaggaagaag ttttctgctc attagtcatc gtttagaccc tttgatttct
    65761 gtggttgatt attggattga gatgactagt cagggtcttc ggcatgtgaa agaagtgacc
    65821 attaccaaac cacttacatc tcagagtagc aatacccaag gggaggtgag atagtatggt
    65881 caaagtagca acccagacac cgattatcag tctcttcttg ctgattttat ccttggaaac
    65941 atctttcatt ccttcgattg ctctgaatct ttcggtagtc gcattttgta ttctctttat
    66001 gctctattac cgtcgattta aaatgttagc ttggatgatc atacttgcca ttttaccatc
    66061 ttttgccaac tactgggcag ttcagttaca cggagatgct tcacaggcag tcatgcttgg
    66121 aacgagggcc tttgtgacag tttgtatcgg ccttgtcttt gtttcctcta tttcactaaa
    66181 agagcttctc ttgtacttgg ctcaaaaggg gctatcacgc tcttggtcct atgccttgat
    66241 tgtggtattc aattcttttc ctctcattca gcaagaaatc aagtccctca aagaagcttg
    66301 cctattacgt ggtcaagaac tacatttttg gtcgcccttg atttacagta aggttctgat
    66361 gacagtcttt aggtggcgcc atctttacct gagagctcta tctgctcacg gatatgacga
    66421 acatgcacag ttgaagaata gctatcggac tttttatatt cctaaaaaaa caaaattaat
    66481 ctacctgctt ttctttttat tgcttcaaac cagtctattt ttataaagga gttattatgg
    66541 aatttacaga tattgcgatg gaattatcca agaaagcttg gcaggcttcc tttcatcatc
    66601 cctttatttt acaattacaa gaggggaatt tagaacctgc cattttccgc tattacctga
    66661 ttcaggatgc ctactatctg aaggctttct cagaaatcta tcatcttttg gctgataaga
    66721 cttcaaacca agagatgaaa agactcttga aacaaaatgc tcagggttta gtggagggtg
    66781 agttatttat tcgccaacaa tttttcaagg aattggaaat cagcgaccag gaaatggagc
    66841 aacatccaat cgctccaacc tgttatcatt acatttctca tatttatagg caatttgcag
    66901 aaccgaactt agccatcgct tttgcaagct tgcttccttg tccttggtta taccatgata
    66961 taggcaaatc acttaatctt aaaccatcac caaatcctct ctatcaacaa tggattgaaa
    67021 cttatattac ggatgagtta gagcaacaga tcagagagga gggagcactg gtcaatcagc
    67081 tctatcgaga aagtgatgag acagataagc aaaaaatgct agatgccttc cacatcagtg
    67141 ttcatatgga agccaagttt tgggagatgg cttaccaaca ccagacatgg aagagcgatt
    67201 tacagtcttt agaaaaagga gaagaataga aacatgagaa agcaccaact acaagttcac
    67261 aaattgacca ttttatctat gatgattgcc cttgatgtag tccttacacc tatctttcgg
    67321 attgagggaa tggcaccgat gtccagtgta gtcaatattc tagcgggaat catgatggga
    67381 cctgtttatg ccttggctat ggctacagtg acagccttta tccgtatgac gactcaaggg
    67441 attccgcctt tagctctcac aggagcgact tttggagccc ttctagcagg tctcttttat
    67501 aagtacggtc gaaaatttta cttttctgcc ttgggagaaa ttgtgggaac aggtattatt
    67561 ggttctattg tttcctatcc tgttatggta ctctttacag gatcagctgc taagcttagc
    67621 tggtttatct acacgcctcg atttttcgga gcaaccttga ttggtacagc gatttccttt
    67681 attgcctttc gatttttaat caagcaggaa ttctttaaaa aagtgcaggg atatttcttt
    67741 agtgaaagga tagactgatg caggaattta caaatccctt tcctataggc tctagttccc
    67801 tcattcactg tatgaccaat gagatttctt gtgagatgct ggcaaatggg attttggctc
    67861 tgggatgcaa acctgtcatg gcagatgatc cccgtgaggt tcttgatttt actaagcaaa
    67921 gtcaggctct cttcatcaat ttggggcatt tgtcagctga gaaggagaaa gcaatccgta
    67981 tagcagcttc ttatgcagct caagtttgtc tcccaatggt agtagatgcg gttggcgtaa
    68041 cagcttcatc cattcgtaag agcttagtca gagacctttt agactataga cctacggtcc
    68101 ttaaaggaaa catgtcagaa attcgaagtc ttgttggatt aaagcaccac ggcgttgggg
    68161 tcgatgcgag tgctaaagat caagaaacgg aggatttgct tcaagtcttg aaagactggt
    68221 gtcagaccta tcatggtatg tctttcttag tcacaggtcc caaggacctc gtcgtttcga
    68281 aaaatcaggt cgctgtactg ggaaatggct gtgcagaatt agactggata acagggacag
    68341 gagatttggt tggagcctta acagccgttt ttctcagcca aggaaagact ggttttgaag
    68401 cttcttgctt agcagtctct tatctcaata tcgctgctga gaaaatagtt gttcaaggaa
    68461 tgggattgga agaatttcgt taccaagtac tcaatcagct ttcgctccta agaagagatg
    68521 aaaattggct agataccatc aaaggagagg tttatgaata gagaagcact tagactatat
    68581 ctggtaacca atcgctatca agattccgtg gaaagctttc ttgcaaaagt tgagacggcc
    68641 tgccgttcag gggttaccat agtccaattg cgagaaaaaa atctcacaac caatcaatat
    68701 tatcaactgg caaaacaagt caaggaaata acagatgctt atcaggtacc cttgataatc
    68761 gatgatcggt tggatgtttg tcttgcggtt gatgctgctg gtctgcatat tggagatgac
    68821 gaactcccag tttcggttgc ccgacaagtc ttgggtcctg aaaaaatcct cggtgtcacc
    68881 gctaaaacgg ttaaaagagc tctggaagcg gagaaatcag gtgcagatta cttggggaca
    68941 ggagccattt ttccgacaac caccaaggaa aatgcaccca tcaccctgat ttcaaccttg
    69001 aaaacaattt gccaaacggt tgccattcca atagttgcta ttggtggctt gacttcggag
    69061 aatattgatc agcttatggg cactggcata gctggtgtag ctgttgtacg tgatttgatg
    69121 caagcagaag atattgaggc aaaaacgcaa gcctttttaa caaagttgca tgacattctt
    69181 tcctaattaa tactcaatga aaatcaaaga gtaaactaga aagctagtcg caggttgctc
    69241 aaagtactgc cttgaggttt tagataagac tgacgaagtc agctcaaaac agtgttttga
    69301 agttgcagat ggaagctgac gtagtttgaa gagattttcg aagagtataa aaactctcta
    69361 attcccttaa agtgggaact agagagtttt ttttcttaat ctttaaaagt tgtatggttg
    69421 actggaccag aaccatgacc gagttgaggg gcatcttgaa tagcttttgt gataaaggcc
    69481 ttggccttat caactgcctg gtaaagactc ttgcccttgg ctagttcagc agtaatcact
    69541 gcagcaaagg tacatccagt accatgggtg tgacaggttt gaattcgtgg gctttcccag
    69601 acaaattgtt cattcttggt aaagaggaaa tctttagcac cacctttgag atgtccgcct
    69661 ttgataacca cagactgagg accaaattct tttaaaatca ggcgaccagc acgctgcatg
    69721 tcttcggggt catggattga aaaaccaaca atctcttctg cttcaggaag atttggcgta
    69781 ataatagttg ctagaggtag taagtttgtt ttgagatagt ctctagcact tgagtcaatc
    69841 aaggcatctc cacttgtagc aaccataaca ggatcaagga catagggaca atccagtttt
    69901 ttaagatagg gttggatgat ttccatgatt tcagtagtag ccaacattcc agtttttaca
    69961 gcctgaggtg gaatatcaga aaagacactc tccaattggg ctttcaacat ttgaggagaa
    70021 acgtgctcga ttagctgaac acctctggta ttttgagcga caagactggt tacaacagcc
    70081 attccataga catctctcgc ttggaatgac tttaaatctg ccataatgcc agcaccacca
    70141 ctagggtcag tccctgcaat ggtcaaagca acgggtaaat aagtcatcta aaacctccca
    70201 accaactgaa gtttgtattc ttaagaacaa gctagtctgt tttagaaagg caatagaaga
    70261 ctgctagtcc ccattatcat ttccacttcc atcagctagc attacctaga ttgagtcaga
    70321 gggatctaac agtcgttaat ctcagcttta cgcaccccta gtggttgttt tcttttttct
    70381 ttagtatagc atatttttat tgtttatata gtaatatttg actgcaaatc gtttttcaaa
    70441 tgattaaaat tctatttttc gaagaaaata ttatttctat aattgacaaa tgtagatttt
    70501 gggagtatac tgttgagtgt aattgacaaa tgtagatttt ggaggtatgg taatgcagat
    70561 ttcagatgca gaatggcagg tcatgaagat tatttggatg cagggggagc agaccagtac
    70621 agatttgatt agggttttgg cagagcggtt tgactggtcc aagtccacgg ttcagacact
    70681 tttggctcgt ctagttgaga aagagtgttt gactcggaaa aaagaaggca agtcctttgt
    70741 ttattcagcg cttttaactc tagaccaaag tcgggattta cttgtccaag atatcaaaga
    70801 caaggtttgt tcccgtagga ttaggaattt gttggctgac ttgattgtag aatgtgaatt
    70861 tactcagact gacttggaag acttggaagc tgtgatttca gagaagaaat caagtgctgt
    70921 aacagaagta agatgtaatt gtatgtaaag gagacgtcat gttaaatagt attgtaacca
    70981 ttatttgtat tgcccttatc gcgtttatct tgttttggtt tttcaaaaag cctgaaaaat
    71041 ctggacaaaa agcccagcaa aaaaacggat accaagagat tcgagtggaa gtcatgggag
    71101 gctatactcc tgagttgatt gtcctcaaga aatcagtgcc agcccgcatt gtctttgacc
    71161 gcaaggatcc ttcaccatgt ctggatcaaa ttgtttttcc agattttggt gtacatgcga
    71221 acctgccaat gggggaagag tatgtagtgg aaatcacgcc tgaacaggct ggagagttta
    71281 gctttgcttg tggtatgaac atgatgcacg gcaagatgat tgtagagtag gtggagacta
    71341 tgacagaaat tgtgaaagca agcttagaaa atggcattca aaaaatccgt atccaagctg
    71401 aaaaaggcta tcatccagcc catatccagc ttcaaaaggg aattccagct gagattacct
    71461 ttcatcgtgc tactccttca aactgttata aggaaattct gtttgaagaa gaaggtatct
    71521 tggaaccaat cggcgtagat gaggagaaag tcattcgttt tacacctcaa gaattagggc
    71581 gacatgaatt ttcttgtggc atgaagatgc aaaagggaag ctatacagtc gttgagaaga
    71641 ctcgaaaatc tctatctctc ctgcaacgtt tttggattac tagtatctgt actgtgcctc
    71701 ttgtgattct catgattggg atgttggcag gtagcattag tcatcaagtc atgcattggg
    71761 gaacctttct agcaacaacg cctattatgt tagttgcagg taagccatat atccagagtg
    71821 cttgggccag ttttaaaaag cacaatgcca acatggatac cttggttgcg ctgggaactc
    71881 tagtggctta tttctatagc ctagttgctc tctttgctgg tctccctgtt tacttcgaaa
    71941 gtgctggatt tatcctcttt ttcgttcttt tgggagcagt ttttgaggaa aaaatgagaa
    72001 aaaatacgtc ccaagctgtg gagaaattac tggacttgca agctaaaacc gcagaagtct
    72061 tgagtgatga tagttatgtc caagttcctt tggaacaagt caaggtaggc gacctgattc
    72121 gagtgcgtcc cggtgaaaag attgctgttg atggtgtcgt agtagaaggt gtctctagta
    72181 ttgacgaatc catggtgaca ggtgagagtc tgcctgtgga caagacagtt ggagatactg
    72241 tcattggctc aaccatcaat catagtggaa cgcttgtctt tagagcagaa aaagttggct
    72301 cagagactgt tttggctcag attgtggatt ttgtgaagaa agctcagaca agtcgtgcgc
    72361 cgattcagga cttgacggat aagatttcag ggatttttgt cccagtagtt gtcattttag
    72421 gaatcatgac cttttgggtt tggttcgtct tgctcaggga tagtgtggtt gtgcttggag
    72481 ctagctttgt gtcctctctt ctctacggag tggcggtttt gattatcgcc tgtccttgtg
    72541 ccttgggact tgcaacaccg acagccctta tggtggggac aggacgtagt gccaagatgg
    72601 gggttctcct caaaaatgga actgtcttac aggaaatcca gaaagttcaa acccttgtct
    72661 ttgataagac cgggactttg acggaaggga aacctgtggt aacagatgtc atcggcgacg
    72721 aagtagaagt gtttggattg gcagcctcct tggaagatgc ttctcaacac ccactggctg
    72781 aggctatcgt taagcgagcg agtgaagctg gacttgagtt tcaaactgtt gaaaattttc
    72841 aggccttgca cgggaaaggt gtttcagggc gaatcaatgg aaaacaagtt ttacttggaa
    72901 atgctaaaat gctggatggc atggatattt ctaatactta tcaagataaa ctagaagaac
    72961 tagaaaaaga agctaagaca gttgtgttct tagctgttga caatgaaatc aaaggcttgc
    73021 ttgctttgca agatattcct aagaaaaatg ctaagctagc catcagtcag ctaaaaaaac
    73081 gtggtctcgg gacagtcatg ctgacaggag acaatgctgg tgtggcgcgt gctattgcag
    73141 atcaaatcgg aattgaagag gtcattgcag gcgtcttgcc agaagaaaaa gcccatgaaa
    73201 tccataaact gcaacagtca ggtaaagtag cctttgttgg tgatgggatc aatgacgctc
    73261 ctgcccttag tgtagcagat gtggggattg ctatgggagc tggaacagat atcgccatcg
    73321 agtcagcaga tttggtgttg acaaccaata atcttttagg agtggtgcgt gccttcgaca
    73381 tgagtaagaa aacctttcat cgtattctgc tcaatctttt ctgggctttt atctacaatg
    73441 ttgtcggaat tccgattgca gcaggagtct tttcaggtgt tggactggct ctcaacccag
    73501 aattggcagg tctagccatg gcctttagtt ctgtatctgt tctgaccagt tcccttctgt
    73561 taaattttag taaaatagac taaaagtaat gactagattt ttttgttata aaacagaaat
    73621 gacgacactt tcaaaactgt attagaatag agaatagaga gttttgagca gatttttaga
    73681 aaagtcagca taaatatgat acagtggaat agtaaaaaat tggagaacgt ttccaattct
    73741 atgtaatcgt attctccaag tctaaaaaaa ttgaaggaga gttatcatta tgactcaagg
    73801 gaaaattact gcatctgcag caatgcttaa cgtattgaaa acatggggcg tagatacaat
    73861 ctacggtatc ccatcaggaa cactcagctc attgatggac gctttggctg aagacaaaga
    73921 tatccgcttc ttacaagttc gccacgaaga gacaggtgct cttgcagcgg ttatgcaagc
    73981 taaattcggc ggctcaatcg gggttgcagt tggttcaggt ggtccaggtg cgactcactt
    74041 gattaacggt gtttacgatg cagctatgga taacactcca ttcctagcaa tccttggatc
    74101 acgtccagtt aacgaattga acatggatgc tttccaagag cttaaccaaa acccaatgta
    74161 caacggtatc gctgtttaca acaaacgtgt agcttacgct gagcaattgc caaaagtaat
    74221 tgacgaagcc tgccgtgctg cagtttctaa aaaaggtcca gctgttgttg aaattccagt
    74281 aaacttcggt ttccaagaaa tcgacgaaaa ctcatactac ggttcaggtt catacgaacg
    74341 ctcattcatc gctcctgctt tgaacgaagt tgaaatcgac aaagctgttg aaatcttgaa
    74401 caatgctgaa cgcccagtta tctatgctgg atttggtggt gttaaagctg gtgaagtgat
    74461 tactgaattg tcacgtaaaa tcaaagcacc aatcatcaca actggtaaaa actttgaagc
    74521 tttcgaatgg aactatgaag gtttgacagg ttctgcttat cgtgttggtt ggaaaccagc
    74581 caacgaagtg gtctttgaag cagacacagt tcttttcctt ggttcaaact tcccatttgc
    74641 tgaagtttac gaagcattca agaacactga aaaattcatc caagttgata tcgaccctta
    74701 caaacttggt aaacgtcatg cccttgacgc ttcaatcctt ggtgatgctg gtcaagcagc
    74761 taaagctatc cttgacaaag taaacccagt tgaatcaact ccatggtggc gtgcaaacgt
    74821 taagaacaac caaaactggc gtgattacat gaacaaactc gaaggtaaaa ctgagggtga
    74881 attgcaattg tatcaagttt acaatgcaat caacaaacat gctgatcaag acgctatcta
    74941 ctcaatcgac gtaggtaaca ctactcaaac atctactcgt caccttcaca tgacacctaa
    75001 gaacatgtgg cgtacatctc cactctttgc gacaatgggt attgcccttc ctggtggtat
    75061 cgctgctaag aaagacaatc cagatcgcca agtatggaac atcatgggtg acggagcatt
    75121 caacatgtgc tacccagacg ttatcacaaa cgttcaatac gaccttccag ttatcaacct
    75181 tgtcttctca aatgctgagt acggcttcat caagaacaaa tacgaagata caaacaaaca
    75241 cttgtttggt gtagacttca caaacgctga ctacgctaaa attgcggaag ctcaaggagc
    75301 tgttggattc acagttgacc gtatcgaaga catcgatgca gttgttgcag aagctgttaa
    75361 attgaacaaa gaaggtaaaa ctgttgtcat cgatgctcgc atcactcaac accgtccact
    75421 tccagtagaa gtacttgaat tggatccaaa acttcactca gaagaagcta tcaaagcctt
    75481 caaggaaaaa tacgaagcag aagaactcgt accattccgt ctcttcttgg aagaagaagg
    75541 attgcaatca cgcgcaatta aataattcct ctcgccgaaa atcaaatatg aaacttgtag
    75601 actttattct ttgattttca tagagcagaa ctttaaaaga tcggagcaat ccggtctttt
    75661 tatggaggag agtaaatgaa tttaaatcaa ttagatatta tcgtttcaaa tgttccccaa
    75721 gtctgtgctg acttggagca tattttggat aaaaaggcag attatgctga tgatggtttt
    75781 gctcagttta cgattggtag tcactgcctt atgttgtcac aaaatcattt ggttcctttg
    75841 gaaaactttc agtcaggaat cattattcat atcgaggttg aggatgtaga ccagaactac
    75901 aaacggttga acgagcttgg tataaaggtt ttacacggac caactgtaac cgattgggga
    75961 acagagtcct tattagttca aggacctgct ggtctagtgc ttgattttta tcgtatgaaa
    76021 taggtcgcgt agtcatttga cgttaacctt agctatttt
//
LOCUS       DBEJJV010000006        75062 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.006, whole genome shotgun sequence.
ACCESSION   DBEJJV010000006 DBEJJV010000000
VERSION     DBEJJV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 75062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.006"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(126..995)
                     /gene="thrB"
                     /locus_tag="ACL3GT_000423"
     CDS             complement(126..995)
                     /gene="thrB"
                     /locus_tag="ACL3GT_000423"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004413 - homoserine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HGR0516139.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(997..2283)
                     /locus_tag="ACL3GT_000424"
     CDS             complement(997..2283)
                     /locus_tag="ACL3GT_000424"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004412 - homoserine dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HGR0516140.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQEFGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2434..3171)
                     /gene="mecA"
                     /locus_tag="ACL3GT_000425"
     CDS             complement(2434..3171)
                     /gene="mecA"
                     /locus_tag="ACL3GT_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HGR0516141.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3371..4405)
                     /locus_tag="ACL3GT_000426"
     CDS             complement(3371..4405)
                     /locus_tag="ACL3GT_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0516142.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4434..5867)
                     /locus_tag="ACL3GT_000427"
     CDS             complement(4434..5867)
                     /locus_tag="ACL3GT_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HGR0516143.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5883..6869)
                     /locus_tag="ACL3GT_000428"
     CDS             complement(5883..6869)
                     /locus_tag="ACL3GT_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0516144.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6871..7974)
                     /locus_tag="ACL3GT_000429"
     CDS             complement(6871..7974)
                     /locus_tag="ACL3GT_000429"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HGR0516145.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTNVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7964..8809)
                     /locus_tag="ACL3GT_000430"
     CDS             complement(7964..8809)
                     /locus_tag="ACL3GT_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0516146.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9088..10362)
                     /gene="psr"
                     /locus_tag="ACL3GT_000431"
     CDS             complement(9088..10362)
                     /gene="psr"
                     /locus_tag="ACL3GT_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HGR0516147.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10359..11207)
                     /gene="pheA"
                     /locus_tag="ACL3GT_000432"
     CDS             complement(10359..11207)
                     /gene="pheA"
                     /locus_tag="ACL3GT_000432"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HGR0516148.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11204..11680)
                     /locus_tag="ACL3GT_000433"
     CDS             complement(11204..11680)
                     /locus_tag="ACL3GT_000433"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HGR0516149.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11673..12956)
                     /gene="aroA"
                     /locus_tag="ACL3GT_000434"
     CDS             complement(11673..12956)
                     /gene="aroA"
                     /locus_tag="ACL3GT_000434"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HGR0516150.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKAVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13048..13386)
                     /locus_tag="ACL3GT_000435"
     CDS             complement(13048..13386)
                     /locus_tag="ACL3GT_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HGR0516151.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13397..14500)
                     /locus_tag="ACL3GT_000436"
     CDS             complement(13397..14500)
                     /locus_tag="ACL3GT_000436"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HGR0516152.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14510..15676)
                     /gene="aroC"
                     /locus_tag="ACL3GT_000437"
     CDS             complement(14510..15676)
                     /gene="aroC"
                     /locus_tag="ACL3GT_000437"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HGR0516153.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15686..16753)
                     /gene="aroB"
                     /locus_tag="ACL3GT_000438"
     CDS             complement(15686..16753)
                     /gene="aroB"
                     /locus_tag="ACL3GT_000438"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HGR0516154.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTELNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKTRGNTLKLVLVS
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(16772..17626)
                     /locus_tag="ACL3GT_000439"
     CDS             complement(16772..17626)
                     /locus_tag="ACL3GT_000439"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HGR0516155.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALENVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17616..18293)
                     /gene="aroD"
                     /locus_tag="ACL3GT_000440"
     CDS             complement(17616..18293)
                     /gene="aroD"
                     /locus_tag="ACL3GT_000440"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HGR0516156.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18290..19453)
                     /locus_tag="ACL3GT_000441"
     CDS             complement(18290..19453)
                     /locus_tag="ACL3GT_000441"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HGR0516157.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20138..21772)
                     /locus_tag="ACL3GT_000442"
     CDS             complement(20138..21772)
                     /locus_tag="ACL3GT_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516158.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEMPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEALVGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPVLTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21753..22502)
                     /locus_tag="ACL3GT_000443"
     CDS             complement(21753..22502)
                     /locus_tag="ACL3GT_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516159.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            22681..24135
                     /locus_tag="ACL3GT_000444"
     CDS             22681..24135
                     /locus_tag="ACL3GT_000444"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004556 - alpha-amylase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HGR0516160.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24225..26843)
                     /gene="alaS"
                     /locus_tag="ACL3GT_000445"
     CDS             complement(24225..26843)
                     /gene="alaS"
                     /locus_tag="ACL3GT_000445"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HGR0516161.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPCITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(26865..27350)
                     /locus_tag="ACL3GT_000446"
     CDS             complement(26865..27350)
                     /locus_tag="ACL3GT_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HGR0516162.1"
                     /translation="MKTFLVKQKFRLGGERFAIKNDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27625..27864)
                     /locus_tag="ACL3GT_000447"
     CDS             complement(27625..27864)
                     /locus_tag="ACL3GT_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516163.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28125..29195)
                     /locus_tag="ACL3GT_000448"
     CDS             complement(28125..29195)
                     /locus_tag="ACL3GT_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0516164.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29192..29965)
                     /locus_tag="ACL3GT_000449"
     CDS             complement(29192..29965)
                     /locus_tag="ACL3GT_000449"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516165.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29962..30768)
                     /locus_tag="ACL3GT_000450"
     CDS             complement(29962..30768)
                     /locus_tag="ACL3GT_000450"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516166.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30749..31906)
                     /locus_tag="ACL3GT_000451"
     CDS             complement(30749..31906)
                     /locus_tag="ACL3GT_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516167.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32066..32971)
                     /gene="murB"
                     /locus_tag="ACL3GT_000452"
     CDS             complement(32066..32971)
                     /gene="murB"
                     /locus_tag="ACL3GT_000452"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HGR0516168.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33083..33835)
                     /locus_tag="ACL3GT_000453"
     CDS             complement(33083..33835)
                     /locus_tag="ACL3GT_000453"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family glutamic-type intramembrane
                     protease"
                     /protein_id="HGR0516169.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(33845..34576)
                     /gene="budA"
                     /locus_tag="ACL3GT_000454"
     CDS             complement(33845..34576)
                     /gene="budA"
                     /locus_tag="ACL3GT_000454"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HGR0516170.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34718..35989
                     /locus_tag="ACL3GT_000455"
     CDS             34718..35989
                     /locus_tag="ACL3GT_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HGR0516171.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLKELERHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36009..36824)
                     /locus_tag="ACL3GT_000456"
     CDS             complement(36009..36824)
                     /locus_tag="ACL3GT_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0516172.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(36981..37634)
                     /gene="phoU"
                     /locus_tag="ACL3GT_000457"
     CDS             complement(36981..37634)
                     /gene="phoU"
                     /locus_tag="ACL3GT_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0516173.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37646..38404)
                     /gene="pstB"
                     /locus_tag="ACL3GT_000458"
     CDS             complement(37646..38404)
                     /gene="pstB"
                     /locus_tag="ACL3GT_000458"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0516174.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38417..39220)
                     /gene="pstB"
                     /locus_tag="ACL3GT_000459"
     CDS             complement(38417..39220)
                     /gene="pstB"
                     /locus_tag="ACL3GT_000459"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0516175.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39231..40115)
                     /gene="pstA"
                     /locus_tag="ACL3GT_000460"
     CDS             complement(39231..40115)
                     /gene="pstA"
                     /locus_tag="ACL3GT_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0516176.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40105..41022)
                     /gene="pstC"
                     /locus_tag="ACL3GT_000461"
     CDS             complement(40105..41022)
                     /gene="pstC"
                     /locus_tag="ACL3GT_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0516177.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41022..41900)
                     /gene="pstS"
                     /locus_tag="ACL3GT_000462"
     CDS             complement(41022..41900)
                     /gene="pstS"
                     /locus_tag="ACL3GT_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HGR0516178.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42474..43778)
                     /locus_tag="ACL3GT_000463"
     CDS             complement(42474..43778)
                     /locus_tag="ACL3GT_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HGR0516179.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43779..44552)
                     /locus_tag="ACL3GT_000464"
     CDS             complement(43779..44552)
                     /locus_tag="ACL3GT_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HGR0516180.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44542..44820)
                     /locus_tag="ACL3GT_000465"
     CDS             complement(44542..44820)
                     /locus_tag="ACL3GT_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HGR0516181.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44820..45221)
                     /locus_tag="ACL3GT_000466"
     CDS             complement(44820..45221)
                     /locus_tag="ACL3GT_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HGR0516182.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45431..46048)
                     /locus_tag="ACL3GT_000467"
     CDS             complement(45431..46048)
                     /locus_tag="ACL3GT_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HGR0516183.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(46038..46811)
                     /locus_tag="ACL3GT_000468"
     CDS             complement(46038..46811)
                     /locus_tag="ACL3GT_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HGR0516184.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46822..47559)
                     /locus_tag="ACL3GT_000469"
     CDS             complement(46822..47559)
                     /locus_tag="ACL3GT_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HGR0516185.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEEYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAEQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(47564..48694)
                     /gene="hemW"
                     /locus_tag="ACL3GT_000470"
     CDS             complement(47564..48694)
                     /gene="hemW"
                     /locus_tag="ACL3GT_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HGR0516186.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48778..49167)
                     /locus_tag="ACL3GT_000471"
     CDS             complement(48778..49167)
                     /locus_tag="ACL3GT_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HGR0516187.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49140..49566)
                     /locus_tag="ACL3GT_000472"
                     /pseudo
     CDS             complement(49140..49566)
                     /locus_tag="ACL3GT_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
     gene            complement(49567..50355)
                     /gene="lgt"
                     /locus_tag="ACL3GT_000473"
     CDS             complement(49567..50355)
                     /gene="lgt"
                     /locus_tag="ACL3GT_000473"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HGR0516188.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEK"
     gene            complement(50348..51283)
                     /gene="hprK"
                     /locus_tag="ACL3GT_000474"
     CDS             complement(50348..51283)
                     /gene="hprK"
                     /locus_tag="ACL3GT_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HGR0516189.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51413..51589)
                     /gene="rpsU"
                     /locus_tag="ACL3GT_000475"
     CDS             complement(51413..51589)
                     /gene="rpsU"
                     /locus_tag="ACL3GT_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HGR0516190.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51729..52436)
                     /locus_tag="ACL3GT_000476"
     CDS             complement(51729..52436)
                     /locus_tag="ACL3GT_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HGR0516191.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52587..53615
                     /gene="queA"
                     /locus_tag="ACL3GT_000477"
     CDS             52587..53615
                     /gene="queA"
                     /locus_tag="ACL3GT_000477"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HGR0516192.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFY
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54276..54665)
                     /locus_tag="ACL3GT_000478"
     CDS             complement(54276..54665)
                     /locus_tag="ACL3GT_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0516193.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54719..55426)
                     /locus_tag="ACL3GT_000479"
     CDS             complement(54719..55426)
                     /locus_tag="ACL3GT_000479"
                     /inference="COORDINATES: protein motif:HMM:NF019142.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR0516194.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKEATDTVIKVPAKSKVEEVFVPFATKYEADNDLSAGQEQEITLGKNGKIVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEISIETEYLDGPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(56126..56677)
                     /locus_tag="ACL3GT_000480"
     CDS             complement(56126..56677)
                     /locus_tag="ACL3GT_000480"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0516195.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(57027..57851)
                     /gene="nadE"
                     /locus_tag="ACL3GT_000481"
     CDS             complement(57027..57851)
                     /gene="nadE"
                     /locus_tag="ACL3GT_000481"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HGR0516196.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(57848..59308)
                     /locus_tag="ACL3GT_000482"
     CDS             complement(57848..59308)
                     /locus_tag="ACL3GT_000482"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HGR0516197.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(59424..59912)
                     /locus_tag="ACL3GT_000483"
     CDS             complement(59424..59912)
                     /locus_tag="ACL3GT_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6773 family protein"
                     /protein_id="HGR0516198.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(59902..60111)
                     /locus_tag="ACL3GT_000484"
     CDS             complement(59902..60111)
                     /locus_tag="ACL3GT_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0516199.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(60497..60967)
                     /locus_tag="ACL3GT_000485"
                     /pseudo
     CDS             complement(60497..60967)
                     /locus_tag="ACL3GT_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(60992..61863)
                     /locus_tag="ACL3GT_000486"
                     /pseudo
     CDS             complement(60992..61863)
                     /locus_tag="ACL3GT_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(62220..62948)
                     /locus_tag="ACL3GT_000487"
                     /pseudo
     CDS             complement(62220..62948)
                     /locus_tag="ACL3GT_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            complement(63208..63519)
                     /locus_tag="ACL3GT_000488"
     CDS             complement(63208..63519)
                     /locus_tag="ACL3GT_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CHY zinc finger protein"
                     /protein_id="HGR0516200.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(63534..64820)
                     /locus_tag="ACL3GT_000489"
     CDS             complement(63534..64820)
                     /locus_tag="ACL3GT_000489"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HGR0516201.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            65417..66001
                     /locus_tag="ACL3GT_000490"
                     /pseudo
     CDS             65417..66001
                     /locus_tag="ACL3GT_000490"
                     /inference="COORDINATES: protein motif:HMM:NF021048.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
     gene            65998..67188
                     /locus_tag="ACL3GT_000491"
     CDS             65998..67188
                     /locus_tag="ACL3GT_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR0516202.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(67703..68695)
                     /locus_tag="ACL3GT_000492"
     CDS             complement(67703..68695)
                     /locus_tag="ACL3GT_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0516203.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            68855..70609
                     /locus_tag="ACL3GT_000493"
     CDS             68855..70609
                     /locus_tag="ACL3GT_000493"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516204.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            70593..72314
                     /locus_tag="ACL3GT_000494"
     CDS             70593..72314
                     /locus_tag="ACL3GT_000494"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516205.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            72325..72909
                     /locus_tag="ACL3GT_000495"
     CDS             72325..72909
                     /locus_tag="ACL3GT_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HGR0516206.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            72909..73604
                     /locus_tag="ACL3GT_000496"
     CDS             72909..73604
                     /locus_tag="ACL3GT_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0516207.1"
                     /translation="MSTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGISF
                     KNPVKYLEYVSMPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            73592..74956
                     /locus_tag="ACL3GT_000497"
     CDS             73592..74956
                     /locus_tag="ACL3GT_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516208.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSINVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFIFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        23096 a        16033 c        13646 g        22287 t
ORIGIN      
        1 tgttttgagc agcctgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa
       61 cttcttttca caaaaaggat atgaaaccct ctggttaaga gtttccccat cctatcttct
      121 attctttatt ttgcttctac acggacacct tgggtatcaa ctctcaagtc atgcagtttt
      181 cctttgaaag gttgcttttc caattctgcc ttaattgttg gcatcttgtc atgagaagcc
      241 agaaccataa ctgtcggccc agcaccagaa aggtaggttg cataggcccc attttctttg
      301 gtcacttgct taatcatcgc aaattctctt accaagtcct gacgataacg ctcatggaag
      361 aggtctccct cgattgcttg cccagcggtc accatgtctc ctgccaacaa ggcagcaacc
      421 gctacattgg cgatagaact tgcagcaaca gcttccttat aagacaattt tttaggcaag
      481 acactacggc tgtcgcgagt acgtaattca tagtttggaa tgtaagctag aaaatcacac
      541 tctggaaagt ctgctacgat agcagagact tgcccttcaa cagaacttgc aataacgaga
      601 ttaccataaa tggctggagc cacattgtca ggatgccctt caatcttggt cgctaactgc
      661 aatttttcat ggtctgataa gttgagttga cccagttggt tggctagttc aatcccagca
      721 acgataaccg agctggaaga acccaaaccg cgcgccaaag ggacatcact ggtcattttc
      781 aagcgtcttg gttgcaagtc tggtacaatt tgcaaagcga ttttgagcaa gagattacgc
      841 tcatcatgtg gaatccattt gccaatctgg tgttcaatca gccactcatc tcgttcttcg
      901 cagacctcaa tttgaagata cttggttaca gctacaccga ccgagtcaaa acctggcccg
      961 atattggcac tggttgcagg tacaataatc ttcatcttat tctcctagca ccttgaaggt
     1021 attcaagagg tcgaattctg aaaccttctt caattcagct gagacatttt caagctgggc
     1081 tttattaatc ttgtgtgtga tgataacgac acgcgccttg tcaccctctt tgccatcttg
     1141 aaggatttgc ttaaaggaaa tatcttgagc attgaagatt tcagccaact tcaagacctg
     1201 accttttgag tctggagcca agattgagaa atagtagttt gctttgacat cttcaggatt
     1261 tgccaagacc aagtcacggc tatattcgtt gaagtctttg ccaatggtac catcattcaa
     1321 acgacgaacg atacggacaa tatcagctac aacacttgtt gcagttggtt tttgacccgc
     1381 acctggtccg tagtacatag actcaccaat accgatagat tctacaaaga cagcgttcat
     1441 tacgccattc acactagcaa gtgggtgcgc tttaggtagg aaggttggag tcacttctgc
     1501 agcaatacct gaagaagttt cctcaataga accaaccaat ttcactacgt aaccaaactc
     1561 ttgagctaca gctacgtctt ctggtgtgat attgcggatt cccttgtggg ctacatcatc
     1621 aaaggcaatc ttcatgccaa aggcaaattg gctcaaaata accatcttgt aggctgcatc
     1681 aatcccatct acgtcattcg tcggatcgct ttctgcaaat cctagacgtt gtgcttccgc
     1741 aagagcatca tcgtaagacc agccttcttc caccatcttg gtcaccatga agttggaagt
     1801 tccgttgact actccaagca cgcgcgtaat tttatcagaa gccaaggaat ttgctaaagt
     1861 acgaagaatt ggaatcccac cagcaactgc tgcttcgtag taaagtgcta ccttgttagc
     1921 ttgagcgatt tctagcaatt ctgcgccatg gacagctaaa aggtccttgt tagcagtaac
     1981 aacgtgtttt ccagcttcca aggcacgagt gataaaggtt ttagcaggct caatacgccc
     2041 catcaattcc actacgatag taatatcctg gtctgataaa atatcatcca cattggttac
     2101 aaagttaaag tcattccctg ctgcaagcaa gcgatttttt tcatcttcat ccttgaccaa
     2161 taccttagca actttgatat ctgaatgtgc tgattgattg atttttcctc cattttcctt
     2221 taggaggaaa ggcacaccac ttgcaacggt accaaatcct agtaaagcaa ttttaactgt
     2281 catctttatc tcctcgaaat tttctaatat agccattata acagaatttt gtgaaaattc
     2341 ctattatagt aaatcactat ttcagtataa aaagaaaaaa cgaatcagac gattcgctct
     2401 tcttaaaatc tgaaaatagc tttccagaaa ggattagccg attttttgca gattgagcac
     2461 tgcatcgtga ctcatcaaga cttgaccata ctcttgtaag actgagcgac tgatatcact
     2521 atcgtctgca aactcgcgca tacgggccaa cagccaagct ggatatgggc ttggatgatt
     2581 ttcaatatcc actaaaatgg tcaaataata gcgctcgttc attttgtaga gttcagaagt
     2641 ttccatttca aaagtcactg tcttggcaaa aactaccaag tcagccaact tagcaaaaga
     2701 aaggatgtag tagatgtaag gttctttctt actctcagct tcttgttcag cctgctcttg
     2761 ctcttcttcc ttggcttcaa cttgctcaag agattgaatg gcttcgatat catccttggt
     2821 tttgtctgcg atgctttttt ccagggtttt gataaattca tctggagaca tttgagccaa
     2881 ttcttccata tctggcaaat ccgataagtc ttcaaaatct agattttggt caatctttga
     2941 cttggtcaca aagacatcta ccttatcagg ttttggagtc acacggaagc tcaacatgcc
     3001 tgtatccaga aagctatcag gcatctctag ttcatccaag atagcataaa agaactcttc
     3061 tgttttttct tgaggaacga gaaagtcagc aatctccatt ccacgatcca tcaaatcctc
     3121 taaagacatc gtgattttta aagttgtatc actaatttgt ttcattttca ttgctagtaa
     3181 cctcatactt tcagttctat ctattatact agatttttac gattttatca aaagaaggct
     3241 cctctatacg gatagatttt ccctagggtc tttctatagg agactccaaa agaaaatttc
     3301 tgcagacaga tagaaaaagc cttcaaaatc agctcttagc cgattttgaa gaccttatac
     3361 atcagaatac ttataattta aaggttgcta caccaaggat agaacgattt aagtttctga
     3421 gaatttgaag actttgctca aatttcttat aacgagtcac tccgtactct tcaacaagaa
     3481 ggactgtatc tctttccaaa agagatgata catcctgtaa atctacaaaa tgcattcctt
     3541 ttaaagcttc ttgactctgt ttcaatttat ctaggatagc tttatttgag ctaacgatgg
     3601 tcaattcctg tccagtattt ttgtatgaca aaacatctgc taggttagca attgttgtaa
     3661 tctctgttac aaaatcaatt tgatactgag aaaaatcacc tactctattg attgttggat
     3721 taaagagata aactaacaca tttcccatca caaccaaaat cacacaaacc actccaataa
     3781 caactaaacg aagaatcaga tttttcacat ttaagccaag cgctgtttca ccatttgcgt
     3841 tcaattcttt agagttgatg gtttccagtt tttcaatttt cacatttgca taggcatgtt
     3901 taaatttctc aatcaaccca tcaatttttt tctctaacaa gtcattggca tctttacttg
     3961 atgtcaaaat tttcacacca acccctgcat cgtcaatcat atagtagacg gtcaattttt
     4021 tccaccaata gtcattcgtt gaatttttca aggttgtttc tgtcgtgtct aattcactgg
     4081 caattttttt caactcactg ggttctacat cattgaaaag ataagctcca ttcaaattac
     4141 catcaatcaa tttcccataa aaatcactat aaccaccaat ttgatgattc aaaatcgttt
     4201 tggccgactc ttttggagga gtgattttat agataagata agttgaataa cttgttgtat
     4261 ctttgacagt gtttttattc ctaactgctt taattgtaaa tggtacagca atgagagcaa
     4321 ataaagcgat gagagctaaa atatttgctt ttcgcttttt ataaagattt gcaaacaaat
     4381 cagctactga ataatgttca aacatgattt ttttctcctt tgtttagtag atactagttt
     4441 tcctttgtaa gcatttttgc tacaaatata atcacaagaa caattcccca gaattgcatt
     4501 gtaaataaat tgaagaaact ttctgaaaag ctgcttcttg gcataaagaa tagattattc
     4561 aagatgagta gggataaagc aaataggatt gtccttgagc gataggctac ttgcagcatg
     4621 gctataaata atacgccgag taagaaacta agcagaaaga ctccaatcat accatagtcg
     4681 gtatacaact ccatgatata actacttccg ataccatgcc ctttcaagta ttccttgttc
     4741 aagacaagat aggatagatt gtgggcataa ctattactat caatagctag ttccacacta
     4801 ttggttgtat gttcaaaggc ttttcctccg aaaatggctc ccaaactccc ccttgcaaaa
     4861 taatcaagaa caggaccaaa agtaaaatta cggaaatctc ggtaagggag gctactgtta
     4921 aatagaaaac ctcgagccag aacaccaaaa ctagtccctt gtttatagat aaagtcaagt
     4981 aagatatccc agaaacctgt atgagaaact tggacattat cccgtacata attgagtact
     5041 cccatcgcta acatgagaat aggagaacct acaaaaatcg ctaacttttc tttaaaccca
     5101 atccattttc ctttttcagt ttgctcccgc ataaagtaat aaacaaaagc aaataaaata
     5161 cttaaaataa agggatttcg tgtcccaatt gccaaatgaa tagtattagc tgcaataaag
     5221 gagacaagca ctgctgtggc ctgcaatttc tttggcttgg ttgccagata catacacatt
     5281 gcatagaccg taaaggtaga caaaatgtag gtaaaataag gcagtttact ttcaaaattt
     5341 gcatagtagg catagtagga agtctgcaaa cgatacaaga gccgttcaaa taaccgaatg
     5401 aaatagaaag gataggttag aagaaaaact cctagtgata caaagcgtaa ccgcttgata
     5461 taaacctctt ttagagaatt tcctatattt gctactttta ttttcttcct agctatgaag
     5521 taacgagcca gaatgcctcc tgtggtcaag cccagaatcg aaaccatgac aactataaag
     5581 gcaaaacgat aggctattgg atgataggta tccaaagcac catccctaaa ataatcaatg
     5641 gtcggtcttg ataccagaaa tacaaaaatg gttaaataga aaataaaatg gattaagtaa
     5701 tacttgatat cattccaaca agcaattaag ctactaacca acaagaacaa taaagtagaa
     5761 agtaagctaa cattattatt attaaacaga tacacaattc cacttactag cgtcaaggca
     5821 taactgacta tggtcaaact aaataataat cgtttcccat caatcacttg gtcacccccg
     5881 ttctaatgta attttttaga tttttcaata tttttcagta ataagaatcg atataaggaa
     5941 atatttatga atagggccaa agcactaatt cttctcccct tacggaaaat tggattccta
     6001 gaaatagcaa aggcatggcc ttttaaaaaa cgatgaatct gagaataggc ttcaaactgt
     6061 ttatactgat catctagcaa catcttatcc agaataaaga agtgggcata ggccaatctg
     6121 aaaaaagcga cctctttcaa gtcaggatag tttttcacaa cttcattata aaacttttgg
     6181 tagatatcaa tataggctaa atccttctct gcatagggtt tggtcgtaat actatcccct
     6241 ctatggaaat agtaataata gggtttagta ttaaccacat acttcttggc caacttgatt
     6301 aaatcaaaat ggtaataggc atcttcgtaa atcaacccct taggaaagga tagggcagtt
     6361 gcaatctgtc tcttgattag cttattgcaa atcgtcccag gtattttttc acctatgagg
     6421 tattccttta gaaatgtttg agaatcacag acaaaatagt catcctgatt ggctgactgt
     6481 gggctttcat cattagcata gacattcatg acaccacagc ttgaaacatc cgcatcttct
     6541 tgaactaatt gctcatataa gctctgaatc atttctggat ggatataatc atctgagtca
     6601 ataaaaatca gataatcccc gtgagcctgc ttcatcccat catttcgtgc ttgcgacaat
     6661 ccttcgttct ttttatgaag cactgacacc ctgtcatctt gttcagcgat tgaatcacac
     6721 aagcgaccac tttcatctgt tgcaccatca tcaacaagaa taatttccag attttgatag
     6781 gtctgcttct gaatggaagc tatcgatttt tctaggtact gcgccacatt atagactggc
     6841 acaatcacac taattaatgc agtttccatg ctactcctct aatagttttt ctacttgttc
     6901 gatttgtttt gtaattgtaa attgttgaat gaattggcta gcctcatcga catcaaagtt
     6961 tgaggcagaa gtcatgtaat tagtaatcgc ctgagctgcc tcttgattgc tctcaatgat
     7021 ttgtccaaat cgtccttctt gggataattc ctcagcccct ccaacgttcg tagagataaa
     7081 agggagtccc agactcaagg cctccacata cactccagga aaaccttctt gtttagacat
     7141 agacaaaaga actttcgtct gagatagata ctgataagga tttttttgat aaccaaggaa
     7201 atgtacatag tcctcaatcc catactcttt gactcgtttt ttcagttcct cttccatatc
     7261 accagccccg ataaaataga gatgatagtt ttttccctct tggtgtaata atcgtatcac
     7321 ttccactaca cggtcagaac ccttattttc ctcaatccgt ccgatagtac agatactttg
     7381 aggagcaatc tcgatatcga tcttctcttg agatttttct agaatagtct gaaaatcata
     7441 tccattgtag attgtctgta atttagaagt ataatctgga taaacttcct tgatagaatt
     7501 gctggtcttt tttgaaatcc ctacaattgt attcgcagca tccaactggc ttctatgtga
     7561 ttctctttta gagctatcct taagaagttc ttcaatactt ccatgaatcc aagatatctt
     7621 cttgacttct cttcttttag agaacaacag tggtggattc ataatggtaa aagaaacttc
     7681 aacatcataa tcatctttta caagcaaacg acgagccagt cttggaaaat aaattctcat
     7741 tctccacaaa aaagctcgta accatctggt ttggcgataa tcttgaaggg attttaaaat
     7801 gcgtacatgc tttggaacag attcatatcc cttgtcaaag tgctccattt caagaatatc
     7861 aatatcatac ttttctggat ccagatttga aacaatggtt gatagaatct tctctgcacc
     7921 acctccaaga gaaaaagacc acataaaaaa taagattttt ttcttagcca ccatattctc
     7981 ccttgtattc tgtataagac ttatccatat cagcgatgac agcatcatga tgcggtacct
     8041 gcttgtctgc tggtggaggc gtcatataat ccccaaaagc agttctgaga tagacatcat
     8101 agccgattgg aataggcatc tctgttcctt caaatggcaa gaaaagattg tcttcaaaag
     8161 atgtgattgg gtacttgttt ctcatgtagc caggacctga gcataattct gtaatgccat
     8221 cacaatcagc caaatcatac ttagtcattt ctttctcagc ttttttccag atgcgataac
     8281 agagagattt tggagtcaaa cccagtaaaa tgcgacttcc ccatttcatg agagcaccat
     8341 gcttttctgg aatagtttgc gcacaaaaga gtgaataaat caaggcccaa cgaacctgtt
     8401 ttttccgctc agctggattt ttcggataat aatccaaagg caaaacatcc aaggccagac
     8461 catgtggcaa atccaaatcc tgctgataag gcttgataca ggtggtttcc ttgtcacgaa
     8521 tggtaataaa aagattacga tcaacaaaat ccttgtgact ctttgacaag aaataacgtt
     8581 catctgcata acgaggccat aattctgcta atttctcata atctttacga ggcataaaaa
     8641 agtctaggtc gtcgtcccaa ggaataaatc ccttgtttcg aagggcacca atagcgcctc
     8701 cgccacagag ataacagagc aaatcatgtt ctttacaaaa ggccacaaaa tattcagcca
     8761 tctccagact acgagcctga attgctttta aatcagtcat attgttcatt attctttcta
     8821 tcgtatcgtt tcattatacc acaaacaagg ggtgaaaatc tattgcagac tgtaaaaaat
     8881 caaagcctga ctgctatcca aatagctatc aaactttgat ttttctgtct tatactcttc
     8941 gaaaatctct tcaaaccacg tcagcttcac cttgccgtag gtataggtaa ctgacttcgt
     9001 cagtcttatc tacaacctca aaactgtgtt tttagcagcc tgcggctagc ttcctagttt
     9061 gcactttgat tttcattgag tattatctta tctcaagccc atttgagcga gcttggtttg
     9121 atatttgttt tgatcaacca gcaagcccaa gcctccataa acatcatagg catctaccca
     9181 gtcacccagt tctggaatcg tcaatttttc aataccattt tttgctccat ccaaaacaga
     9241 taaaccgttt gttaggagga aagtataggg tacgttggtt gaggtcatag caaaaacctt
     9301 tccaagagct tcagaaccag tgaaaagttt agtgggatct ttaatttgct ctaaaattgc
     9361 tgttaaaact tgttgctgtc tttttgtacg gccgtaatcc gcctcatcat catcacggaa
     9421 acgagcataa ttgagcaggg tcgagccatt catctgctgt tttccgactt taatggtttg
     9481 ggttggagac tcagtctcgg tagcgtataa atcatctccg actgtagctt ctgttagggg
     9541 acgcccattc aatgttgaaa attgagcatc aatcgtcacc ccatcaggga aaagcgtgtc
     9601 aatcgctgtg gcaaaggcct ggaaatcaac caaggcgtag tacttaatgt ccaagtcaaa
     9661 attatctttc aagacttggc gaaccatttc tgcccctttt tgcccctctt gttctcctaa
     9721 ctcgtaggct acgtttaact tgttatctgt ctgttttcta ccgttaatca cttgactata
     9781 accatctata tagaccaaat tatcacgcat gaaactgact agcttcattt tcttatctga
     9841 gcccccgaca tttaatacca taatagagtc agttcgtgtc tcaacactgt tctggccgat
     9901 tcgaccatca gtacccatga ttaaaatatt aactccatct ctagtgtcct gaccattaaa
     9961 gacttctact tgagctgccc gggcatcagc agttttcttt gcgctagcat cttggtaacc
    10021 acgcaaaaac atgaatacca tggccaaagc cacacagacc aaaagtgaaa aaatcaccat
    10081 aaaaattcgt ttaagacgga gcttccgtct tttctttttt ggagggaaag agagtgcttg
    10141 tgatttggat tgtgagcgac tccggttcgc atagcttggt aagtcaacct gctcttctct
    10201 ttcttgttcc aagctagagc tactatttcc cctagcaaga gttagctttt cttgcaaata
    10261 ggcaaactca tttttttctc tctcattgag atagtgaata ttttttagca aataatcata
    10321 acgcaactgc tcatgatgac ttaagggatt ttctttactc atcttctctc ctttccatgg
    10381 tctgatattg gataaatagg ataggcaccc agaattttat actggattcc aatcgcttct
    10441 aattcttttt gggcaaagtg gaccaagtcc ttatcggtat aatccacatc gataatgaaa
    10501 aagtattcac ccagtgctgt cttgagtgga cgactttcaa tttttgtcaa gtcaattcct
    10561 cgccaagcaa aggtcgacag ggccttataa agtgcacctg gaaggttgtc aggtaatgtc
    10621 aaggccaaac tcatcttttc agtttgtgct tgcaagggaa tactaggctt ttcagctcct
    10681 agaacccaga aacgtgtgaa attggcttcc atttcctgaa tatcctcggc aatcagttcc
    10741 aatccatatt cttcagcaga acttctaggt gcaactgctg caaagggctg gtctggatgt
    10801 tcggaaataa aacgggccgc ataagctgta ctagctgtta cctcgatttg agcctctgga
    10861 tattgttcat cgatgaattt ctttccttga gccaaggcct gtggatgtga aaaaatcttt
    10921 tcaatcttag tatggcctgg aaccaccatc aactgctgat gaataggctg aacgatttct
    10981 gctactgctt ggatgtgagc ctgatgaaaa agatagtcca aggtttcatg aacactaccc
    11041 tcaatagaat tttcaactgg caccacagaa tagtccacta atccttgctc ataagccttg
    11101 atgacatctg taatgttagc aaaagcctgc aattcctcat gaggaaaagc tatctgcaca
    11161 acgtggtgtg aaaatgatcc cttgggacct agataagcaa ttttcatctt agttcctcta
    11221 taatttcctc tgggcttagc ttggtcacat ccaaaacccg actagccact tcctcatacc
    11281 aagcctgtct ttcttgaaaa atagctacta gttcttcctt gctattattt agaaaaagcg
    11341 gtcgctgatt gtccttatca gctgcgatac gttggtagag ggtttcaaaa tctgctttca
    11401 ggtagatgtt atctgtatta gtcttgagta agtcacgatt tctctgagaa ataaccactc
    11461 ctcctccagt tgacacgact tggtctgttt gtagtaaatc agctaggact tctgattcta
    11521 cctgacgaaa ggctgcttct cccttttcag cgaaaaaatt cgcaatggac atacctaggc
    11581 gcttctcaat cagagcatcc atatcaaggt aattagggtc caagcctctt gcaatagtcg
    11641 attttccagc ccccataaac cctaataaca ccttagccat gaatcaagct ctccaaatca
    11701 tcaaagaaac taggatagct ggtattgatg gcttctgcac ggtcaagctc cacctctcca
    11761 tctgcaacca agagggctgc gatagctgtc atcatgccga tacggtggtc accaaacgta
    11821 ttgactctag caccgtgaag agctgatttc cctttgataa tcatcccatc tgccgtagga
    11881 gtaatatctg ctcccatact atttaaggcg tctgccacaa cctgaatacg gtctgtttcc
    11941 ttgaccttga gctcctcagc atccttgata actgttacac cttgggcttg agtcgcaagc
    12001 agggcaataa tgggcaattc atcaatcaat cgtggaatca aagcgccacc aatctctgtt
    12061 cctttcaagt cagaagactc aacagtcaag gtagaagatt tagcgactgg atcgatttca
    12121 gttatttcca attttccacc catggcacga atgacatcaa taataccggt gcgagtttcg
    12181 ttgatcccca cattctgcag cactagacga gaatttggaa caatcaaacc tgcgactaac
    12241 caaaaggctg cactggaaat atctcctggt acgaccgcct tctgtcctgt caatttttgt
    12301 ggcccttgga ctgtgatttt cttaccgtcc acacttaaat gaccaccaaa ttgtttcaac
    12361 atatcttcag tatgattacg ggtgcactct ttttcgataa taactgactc ccccttagct
    12421 tgtaaggctg caaacatcaa ggctgacttg acttgggcag aggcaattgg caactcataa
    12481 tgaataggtc ttaggttttt cgtccctttt aagcgaaggg gaggcaagtc tcgttcagtt
    12541 tgccctgaaa tgctgacgcc catttttttc agtggaaggg tcacacggtc cataggacgt
    12601 ttggaaagac tatcatctcc aaacatctct acttcgaaat ctgcaccagc aaggacacct
    12661 gaaatcaggc gaatcgaggt gccagaattt cccatattaa gggcattttg tggcgctttt
    12721 aagccagcca tgcctacacc ttgaatggta ataaccccat ctttatcctc aatttcaaca
    12781 ccaaggtcac gaaaaacctg catggtcgaa agaacgtctt cacctcgcag aatatcataa
    12841 accttggtct caccctcagc caaacttcca aagataatgg aacggtggct gatagacttg
    12901 tcacctggga cgcggatact accatgtaaa tggcgaatgt ttgtttttag tttcatactg
    12961 gacctcatac ttgcaatact tttacctatt ttatcataaa aagccagaaa ttccttaaaa
    13021 attcctgact ttaggatcgt tcttttctta tttcagcaat tctgaaactg gttcaaaaac
    13081 aattttttca atgtcagaaa ggtaaatggc caattgttgt tgcttggtaa agaattctga
    13141 caagaggcta tttccttgaa tctgtttacc aaagccttcc atcttagctt ggaaggacgc
    13201 atctggcatt tgacctgtat gtgctagttt ttgaatttcc tcttgaaagg caagatattc
    13261 tgtaaagatt ttgcttgcct cagcatctgc tgcaatcgca tctttagctg ctttaacagc
    13321 cttgtattct ggtaatccgc gtagaccgcg actgagttcg tttgcactat cgtaaatatt
    13381 tgacatgttc ttctccttat ttgatgacga ctgtatagtc ggtattttct gttatgagat
    13441 gctcagctct ttccaagtct tgagcatttt taaatgaaat ttgtaggatt ccgtgaatat
    13501 cctcacgatt ttcctcgttg atgtggatgt taaccaagga agtcccacgt agcagttcca
    13561 aaatccgcag gatgacatct tcttcatcag gaacgtcaac atagaggtcg taagagctat
    13621 ccacaccacc acgcttatgg atttccatgg tctggcgttg ttcacgcgct tggttaaaaa
    13681 agttccaaat ttgctcttca tctcccttac taatggcctg accaatcact tccaaacgtt
    13741 ccttgaaatc ctcaattcta tccagaatgg tctcgctatt ggacaagaga atggaggtcc
    13801 acattcctgg ctcgctttcc gcaattcggg tcatatctcg aaaaccacct gccgcaaagc
    13861 gccttgccat ctcatgctct tgagcataga ccgcagtctg ctccatgaga ctagaagcca
    13921 aaatatgagg aaaatggcta atctgagaag tgacacgatc atgctccttg gcatcaatct
    13981 cgataaaacg agcatgaaga cctgaaagca gatccttcat ttccttaagc gtgtcctgac
    14041 ttgtcaggct tgaaggtgta aagatataat aggcattttc aaaaagattg acatctgccg
    14101 aagcagcccc tgtcttgtga ctaccagcca tgggatgggc cccgacaaag cgaacagact
    14161 tgccagccaa atactgctcc gccgcatcca caatggttga cttggtcgaa ccagcatctg
    14221 aaataataac gccttctcgc aaatccaaat tggccaactc cttaatgaaa gcaatagttt
    14281 gtttgattgg caagctgagg ataatgacat ctgccaaagg agcaaaacta gcaaaatcat
    14341 ccgttgcacg gtcaatcatg ccttctttca aggcgatatc tctcgaagct tgactacgat
    14401 tataacctaa aatttcataa tctggatgat cgcgtttgat accaagtgcc atagaggctc
    14461 caatcaaccc aagacctgcg atatagattg tttttgccat aggaactcct taatagttct
    14521 ttgtatagtc tcggtgtttg gctaccgctt cttttagttc ctcaagatta tctgatgaga
    14581 atttttcgag gatttcttgc gccagaaccg ttgctacaac tgcttccatg accattcctg
    14641 cagctggaag agcagtcgga tcacttctct ccacggttgc cttgtaaggt tcgtgggttt
    14701 cgatatccac actcataaga ggtttataaa gagtaggaat gggtttcatg accccacgaa
    14761 caacgatggg ttgcccatta gtcataccac cttcaaaacc acctagatta ttggtacggc
    14821 gagtataacc gtcttcttta gaccagagaa tttcatccat aacttggctg cctttacgat
    14881 aaccagcctc aaagccaaga ccaaattcca cccctttaaa ggcattgata gagacaacag
    14941 cttgagccaa tcttgcatcc aattttctat cccattggac ataggaacca agaccaactg
    15001 gaacgcctcc gacgactgtc tccacaaccc caccgatggt atcaccatca cgtttgattt
    15061 ggtcaatata gtccttgatt tcctgttctc gttcttggtt aacaatagaa acttcagact
    15121 gggcagctct ttgcttaatt tcagcgactg tcagattttc aggaacatcg atttccttgc
    15181 caccaaagac cacgacatgg ttggcaatct ccatatccag ctcagccaag aggcgtttgg
    15241 ctactgcacc aactgccacc cgcatggtgg tttcacgagc tgatgaacgc tccaaagaat
    15301 ttcgcaaatc atcaaaacgg tacttaatcc ccccaaccaa atcggcatga cctgggcgag
    15361 gatgagtaat tttccgcttg cttttaaggc ggtcttcaat gtcctccgca gacatgatgt
    15421 ccagccattt ctggtggtcc ttattgatga catccatagt aataggcgcc cctgtcgtct
    15481 tcccgtggcg aacgcccgaa gtaaagacaa cctggtcact ctcaatcttc atacgaccac
    15541 cacgaccgta gccaccctga cggcgtctaa ggtcctcatt gatatcctca gctgtcaatg
    15601 gaagtccagc tggaattccc tcaataatag ctgttagacg ggggccgtgt gattctcctg
    15661 cagttaaata tctcatacac tctccttatt ttaccaagta gtctttcatc tcttccagag
    15721 aaactgggtg aatgatcgct gaaccaagct ctgacaccaa gaccaatttc aaggtgttac
    15781 cacgcgtttt cttgtcatga gtaagagcct gataaagctt gtcaacttcc caattttcat
    15841 agtcaacagg caagccgaat ttctgacaca tctctgtgat agattgggta atgccagctg
    15901 gcatgaggcc tttttcctca gcaaccttgg aaatctgtac cattcccatg gcaacagcct
    15961 ctccatgcat gaccttgcca taaccggcag tcgcttcgat ggcatggcca atagtgtggc
    16021 caaaattgag gtaaagacga ataccattgt ccaactcatc ttcaaccacc atcttgcgct
    16081 tcacctgaca agaatgttca atcaaggtct ctgcatgttc caaaatgctc tcaacagaac
    16141 cattcagttc cgtcaagaga gcccacagtt ctggatcctc aatcaagcca tacttgataa
    16201 cttcacccat cccttcaatc aactctcttt ttccgagggt ttcaagaaca agtggatcaa
    16261 tcagaacccc atctggttgg gcaaaggtcc ccaccatatt tttagcaaat ggtgtgttaa
    16321 cgcctgtctt tccaccgata gaagaatcaa cctgagctgt caaactagtc ggaatctgaa
    16381 caaagtgaat accccgcata taggtagagg ctacaaatcc agccaggtcc ccaacaacgc
    16441 caccaccaag agcaacgatt ccatcgctac gagtcagacc ttgcttgact agaaattcat
    16501 agactttctg aacagtagtt aaattctttc tttcttcacc ttctaagaaa tcaaaaacag
    16561 ctacctgaaa accagcatct tctaggctga gcttgacctt ctctgcatag agagaggcta
    16621 catggttatc tgtcacaatg actacctttt gcggttgcca gagttctcgc aaccactgac
    16681 cagcctgggc catacaacct ttttcaatct gaatatcata aggatgatga ggaatatcga
    16741 ttctgatttt cataggagag tctccctttc tttattggta tttttctgtt aaagactgcc
    16801 aaatctcttc tgtcggcatt tccttgcctg tccacagttg aaaagcttct gcagcttgat
    16861 agagcaacat tcccagacca ttgactgctg gattgccctg acttctagcc catttcaaaa
    16921 acggtgtttc aaagggttgg tatatgatat ctgcaactaa gagagtttct ggtaagacta
    16981 tgttttcagg aacaggagag gattggccat ccatgcccac actggtggca ttaactagca
    17041 aatccgactc ggcaatcctt gcttgcagtt cagaaacatt ctctaaagca cacaaatcca
    17101 ctttaaaacc tgtctgctcc tgtaacttgt ctaggtaagg tcttgttttt tccatagaaa
    17161 cggaacgaac aaagaccgaa atctgactga cgccatccaa aatagcctgt gccaagattg
    17221 atttagccgc accacctgca cccagcaggg tcatcttttt acctgaaatt gtaaaagaag
    17281 gcaagcactt aaaaaatccc ttgccatctg tattatatcc aattaaattg ccattctcat
    17341 tgacaaccgt attaaccgca ccaatcaagc gcgcttcatc gctcagctta tccaaataag
    17401 gaatcacctg ctccttatag ggcatggaca gattgatgcc aaacatctgg tagcgacgaa
    17461 tattggccac tgtttctgcc aagtcactcg cttcaatctc ccaagccaca taagcaccgt
    17521 tggtagctgt cgcctcaaag gctctattgt ggatgaaggg agaaatagaa tgcttaatag
    17581 gattggcaac aactgcagct aaacgtgtat agccatcaag cttcatccaa aatctccctg
    17641 atttttttca tgctagctag agaaatctgc ccaggggcac taacctcatc cagactggca
    17701 aaagaccaac tcgaaccagt cacatccgca gtgatacgag agaccttgcc caccttaccc
    17761 atagaaatgg tcacatattc ctgttcagga ttgagggttt taaagcctcg tgtatagttc
    17821 atcaagtcta agacatcctg ctccgtgtga gccatcaccg caaccttaac aagttttgga
    17881 tttaggatcg tcaactctga caagatttcc atcatgttct caggtgtttc ttggaaatta
    17941 tggtaactca aaacaagatt tgggaagtcc agcatttcct caaaaacatc cttgtagcta
    18001 tagtactcaa aatcaatata gtctggttga tagaattgcg caacttcctt gattagatgg
    18061 atatactctt ctggagaaag gtcgatttct ccaccttcgg agcgagttcg tagcgtgaaa
    18121 accaactcac ggcctgcgaa tttttcaaaa atggctggag ctacctgcaa aatcgcttct
    18181 ttaggcagat agtcggcacg ccattcaatg atgtcggcat ccaggtacct cgtggcatcc
    18241 agagcctgag cctcctctaa acttcttggc attactgaaa cgattaattt catttactaa
    18301 ccttcatact aatcaccttg aggtaattac tactttcatc ttttttatta taggcaaaat
    18361 ctgctggaag accatatttg tttaaaatct ggtaacttct tcctgcaaag cctttatcaa
    18421 tttgttctgt aaatttctga cgggaaacat tggcagcatt ggtactggca atgataatcc
    18481 ctcccggatt taaaatctca agactctggg aaatcaactt gtgataatcc ttggccacag
    18541 agaaagtttg ttttttattc cgagcaaagc taggcggatc taggacaatc acatcgtagg
    18601 tcaagtcttt gcgtttggca tatttgaaat actcaaagac atccatgact ataaaacgat
    18661 gctcgtctgt gctgagccca tttgcctgaa aatgcgcttg agacaattct cgtgaacgtt
    18721 tggctagatc aacagaagtt gtctggctag ctcctcccat ggccgcagct actgaaaaag
    18781 ccgctgtgta ggaaaacata ttgagcaagg atttacccat agccaagccg tcaactaaac
    18841 taccgcgaac ctcatgctgg tctaggaaaa ttcctgtcat caagccatca ttcataaaga
    18901 cttgatacag gacaccattt tctaaaacag tgaaaaagtc aggtgcttct tgaccataaa
    18961 catgggcaga ttcatagtca aaacccttaa agcggatttt ctcataagcc cctaaaacct
    19021 cagggaaaac ctgtctaaag gcttctgata tagtctgacg aatctgataa acataagagt
    19081 tataccaaga aaagacggcg tagtcgccat aaaggtccac tgtcagaccc ccaaagccat
    19141 ctccctcttg attaaagaga cgaaaggcag ttgtcaaatc atcttgatag taggcgtttc
    19201 tcttttcttt ggcttttcta aacaacgttt caaagaaagt ttgattgaag gccaccttgt
    19261 ctttgctgac aaaccagccc aagcccttgt tttgctgaga aaggtaggca gtcccaagaa
    19321 agtttccttc ctgaccctgc acctctactt cctgatcctt aagattgaca ttctcaagat
    19381 cactggcttc tagtaaaact agccccttag caagcttctt ttcaaccctt ttgctgactc
    19441 ttattctatt cataactacc attatatcaa acttttagac aattctcaaa aaagaaacta
    19501 cccttgcttt tttactcttc ttttaaaaaa tggtatacta gacttcctgc aaaactagga
    19561 aataaatgtg taagaatcac aataaaaaat gctcttccgt cttggaggag catttctttt
    19621 tatcaacgaa aatcaaatag caaactatga aactagcctc aggttaaccg tgagattata
    19681 ggtagagagg ttgtatcagc aatatgtgtc tgtcaaattt agtgacaaag gtagtagaag
    19741 aaagatgaag aaataaatca gcttcagtag gtatctggaa aatttgattt tatagagaag
    19801 ccttttgtta caaactcaat atactatcaa taaataatat tatagaagca acaataatta
    19861 aaatttcacc tatttgcatc attctatttc gaactctaaa tatatgttct atcaaaaata
    19921 cttggatcac acacattata ggaattaacg tttttgaaat tgaaaaatat cccaataaat
    19981 aaactataaa caacaataat agaactatat tatatttctt attcaaaaca ttcctcccta
    20041 tatttttgat taccaatctt aatcatttac aactacattc taacaaacta taaaagcgtt
    20101 tgtcgaattg aatttatcaa gcaagcaacc aactatctca tcttttttct atttctgcca
    20161 atatgcgtga caggtaataa tgatagccaa aaatagcaag agcaagcaag acgataagag
    20221 ctcctactcc caagttgatg gcaaggatag gggagagaga ctgaaccaag aatatgctcc
    20281 caattacaag ggccatcagg attgcactat aaataaacaa taaaactatg gcgactatgc
    20341 catttgaacg attcaccagg tccgtaatgc tactccaatt ggttgacaga tttttaacgt
    20401 ccttaaagta atggtggcaa gaaaggatga cactggcaat gatccagact acaagaaggt
    20461 aaatcatcga aaggatggac aagcctagat atagagaaag accgagcaaa gtcagaactg
    20521 gtaaaaagga ctgaacagca aagataatcc aaaatttcac tttcacataa cgagcaaagt
    20581 caaagggtaa actcttcaga aaatcaacat tttccctctc caaggacaag gcaattgaat
    20641 gcaggctggt gatattgtta ttgacaactg ctataaacac tcctacaaaa aacaagggta
    20701 accagtatgg aggatgaatg tctggaacta tctgagaatc tcggattttg gaaatcagac
    20761 tgatcatcat gagataagga aggaaagcac ttgtaaaaag cactgtaatc acaccagtcc
    20821 cctgtcccaa gagggtgagg tggtagcgta aaaccatacg gaaaaagccc tttttagtag
    20881 ttgaaatcct ctccttgctg cgacgttctt ttttgacctt ctcctcactg ttaagcagga
    20941 tcacgtcata aaaacgagga aggaccttct ttttggtcag ataaagcagg aagagagtta
    21001 gtcctatcca agcgagcaga cccactaagg cttctgtcga aaaaggctcc actgctattt
    21061 tgtaaaagat atgaagagga taaaggagaa atggaatgtc tctaactttg tcaacaatac
    21121 ttccaaaagt cgactgaaga aagaagataa atattaaagg tatgagaact cctatcccaa
    21181 tcatcacatt cgaaaaaata gactgatact ttctgaagac cctagtctga gccaagaaat
    21241 gtactgccac taccgtcact aaagtaacag agacaaataa taaggtcaag gacagtagca
    21301 tcaaaggcaa acccagccaa agagaaggag ctagactaat atagagggct agaaaataag
    21361 ctaggattgg tacaattcca gttagagctg gcaagaggac agacagacct ttggccatta
    21421 taatctctga ttctttaaag gcatagggcc tataggaggc caggtcctta ctctcataaa
    21481 agacattgta aaaggcagtg aaagaagttg aaaaggccag caccagtaaa atagcaacca
    21541 tcgagctaaa ataaataggc atttcctcaa aaggaaaatg aatggctata ttactaaaac
    21601 agatgagcat caagagactg gaaaaaatgt aagaacttag gactctagca gaaacattta
    21661 cttttttccc aggattctta gcctgcttct ttcgtagatt agccagatta gcttcttgag
    21721 atgaatagag gatattgata tcaactaatt ttttaatgac cttgagacgc atccgcaacc
    21781 tcctcttttc taccagcaag actaaggtag atactttcca aaaactggtc tgggtggtct
    21841 ttcctcaagt cctctacctt accacaataa atcaaatgcc cctttttcaa aatggcaatc
    21901 cgatcacaga cttgctctgc cacctctagg acatgagttg aaaacaagac tgtcttccct
    21961 ttttgtgcat gttccttcat catctgtttc aaatcaaagg cagcctgggg atccaaacca
    22021 gtcaagggtt catccaagac ccaaatatcg ggatcagaca agagtgctcc gatgacaaag
    22081 actttctgac gcattccgtg agaaagagtt tcaataacct gatagcgatt ttcagcaaaa
    22141 tcaaaaacgt tcaatagcct agctagacta gcctccaagt cagatctact cagatcatag
    22201 gatgaggcga tcaattccca aaattcattg gccgttaagc gtaaaaataa gtcaggcgag
    22261 tctgctacgt agccaatctt tcgtttaata gccaagcgat tttccgataa ctcctgaccg
    22321 tctaccaaaa tacgaccact gctgggtgaa atgatactga ctagggattt tatggtggtc
    22381 gattttccag ccccattatg accaatcaag cccataatct ctccattttc aatctgcaaa
    22441 ttgagattac tcaaggcctc tttatcacca tacaacttac taacattttg aaattcaatc
    22501 atgggacaac tcctatcttt atctgtatta tacatcgcta tactagcact ttgatacaaa
    22561 aaaatcaata ctttatttta agtagttaaa atagtttcct tctatcttac gcaaacgttt
    22621 gcaccaagag atactttatg atagaataaa gaacaagatt gacaagtaag aggaaacatc
    22681 atgcaaaatc aaacactcat gcaatacttt gaatggtatc tgccccacga cggtcaacac
    22741 tggacgcgtc tggctgaaaa tgctccacac ctagctcatc tggggatcag tcacgtctgg
    22801 atgccaccag ccttcaaggc aaccaacgaa aaagatgtcg gctatggggt ctatgactta
    22861 tttgacttag gagagttcaa ccaaaaaggg actgtccgca ccaagtatgg tttcaaagaa
    22921 gactatcttc aagccattca agcccttaaa gcacagggaa ttcaacctat ggccgatgta
    22981 gttctcaacc acaaggctgc tgccgatcac agggaagcct ttcaggtcat cgaagttgat
    23041 cctgtagacc gtacagttga acttggagaa cccttcacca tcaatggctg gactagtttt
    23101 accttcgatg gtcgccaaga tacctataat ggcttccact ggcattggta ccacttcacc
    23161 ggtacagact acgatgccaa acgcagtaaa tctgggattt atctgatcca aggggacaac
    23221 aagggctggg ctaacgagga attggtcgat aacgaaaacg gaaactacga ctacctcatg
    23281 tatgccgacc tagactttaa acatcctgaa gtcatccaaa acatctatga ctgggctgat
    23341 tggttcatgg aaacgactgg tgtagctggt ttccgtttgg atgccgttaa gcatattgac
    23401 tctttcttta tgcgcaactt catccgcgat atgaaggaaa aatacggtga cgatttctat
    23461 gtttttggtg aattttggaa cccagacaag gaagccaatc tggactatct cgaaaaaacg
    23521 gaagaacact ttgaccttgt cgatgttcgt ctccaccaga atctctttga agccagtcaa
    23581 gctggcgcaa actatgacct tcgtggcatt ttcacagata gcctggttga actcaagcct
    23641 gacaaggctg tgacttttgt cgacaaccac gatacccaac gaggacaagc ccttgagtct
    23701 accgttgaag aatggttcaa gccagcagcc tatgccctca ttttgttacg ccaagacggc
    23761 cttccatgtg tcttttacgg agactactat gggatttcag ggcagtatgc tcaacaagat
    23821 ttcaaagaaa tccttgaccg cctcctagcc atccgaaaag atttggccta tggagaacaa
    23881 aatgactact ttgaccatgc taactgtatc ggttgggtac gttcaggtgc tgaaaatcaa
    23941 tccccaatcg cagtccttat ctcaaatgac caagaaaaca gcaagtcaat gtttgtcggt
    24001 caagaatgga ctaatcaaac ctttgtagat ttacttggta accaccaagg tcaagttaca
    24061 attgatgagg aaggttatgg acaattccct gtctcagcta gatccgtaag tgtctgggca
    24121 gtcaatacca tctaatagct cataataacc aagctaggtc caagcggatt tggctttttt
    24181 gtattcacaa aaagacctac ccaaatggat agatctttac ttgattacaa tttacctgct
    24241 actgcatcca acaattcttg gatcttagct tggttgcttc ctcctgccat ggccatgtct
    24301 ggtttaccac caccacgtcc atcgatgatt ggtgctaatt ctttgacaag gtttcctgca
    24361 tgaaggtctt ttgtcttgct tgctacaagg acattgactt tgtcaccgat agcagcaact
    24421 aggacaagaa gatcagagta gtctttttgt ttccagttat ctgcaaaggt acgaagggca
    24481 ccggcatctg atacagacac ttgactagca atgtagcggt gaccgttgac ttccttcaca
    24541 tccttgaaga tatcgcctgc ggctgcagct gcggcttttt ctttcaactc agcattttct
    24601 ttttgaagtt gacgaagttg ttcttgaagt ccttctacct tgtgaggtac ttccttgact
    24661 tgaggtgctt tcaaggttgc tgcaacagct ttaagagcgt cctcttgttc acgataggct
    24721 tcaaaggctt ccttaccagt cactgccaag atacgacgag ttcctgaacc gattccttct
    24781 tctttgacaa ttttgaagag accaatctca gaagtgttgc caacgtgggt accaccacaa
    24841 agttcaatag agtagtcacc gatagtcacg acacgaactt ccttgccgta tttctcacca
    24901 aagagggcca tcgctcccat ttctttagca gtgtcaatat ccgtttcaac tgtcttaact
    24961 tcaagagctt cccagatttt ttcgttgact tgctgttcaa tcgcacgaag ttcctcagca
    25021 gttactgctt ggaagtgggt aaagtcaaag cgaaggaatt caacttcgtt aagagatcct
    25081 gcctgtgttg cgtggtttcc aaggatattg tgaagggcag cgtgaagcaa atgagtcgca
    25141 gtgtggtttt tcatgacacg gtgacggcga ttgctatcaa ttgccaaggt atattcttgg
    25201 ttcaaggcaa gcggtgcaag gacttcaact gtatgaaggg cttgaccatt tggggctttc
    25261 tgaacattgg tcacagtagc cacaacctta cctgactcat ccaagatttg tccgtagtca
    25321 gctacctgtc cacccatttc agcataaaat gacgtttccg caaagataag agaggcagtt
    25381 ccttctgaaa cagcttctac ttctgcattg tccgccacga tagctaccaa tttagaagac
    25441 aattggctag cattgtagtt gaagacactt tctacagtga tgttttgaag agtttcattt
    25501 tgcataccca ttgagccacc cttgacagct gaggcacgcg cgcgttcttg ctgttctttc
    25561 atggctgctt caaaaccttc acggtctaca gtcataccag cttcttcagc gatttcttca
    25621 gtcaattcaa ctgggaaccc ataagtatca tagagtttga agacatctga accagcgata
    25681 acagattgac ctttttcttt caagtctgct acaatgcctt gggcaaagtg ttgacctgag
    25741 tgaagggtac gggcaaatga ttcttcttcg ctcttaacga ttttctcaat aaagtcacgt
    25801 ttctcaagca cttctgggta gtagctttcc atgatttttc caacagttgg aaccaatttg
    25861 taaaggaaag gctcgttgat acccaatttt tgaccatgca tagaagcacg acggagaaga
    25921 cgacgaagaa cataaccacg accttcattt cctggaaggg caccatcacc gatagcaaat
    25981 gaaagagaac gaatgtggtc tgcgataacc ttgaagctca tgttgtcgcc atcttggtca
    26041 taaaccttac cagacaattt ctcgacttca cggataatcg gcatgaagag gtccgtttca
    26101 aagttggtct tagccccttg gataacggcc accaaacgct ccaaaccagc gcccgtatca
    26161 atgttcttat gtggcaattc cttgtattcg ctacgaggaa cagcagggtc tgcgttaaat
    26221 tgtgacaaaa cgatgttcca gatttcaata taacggtcgt tttcaatatc ttctgcaagc
    26281 aggcgaagac cgatattttc tgggtcaaag gcttccccac ggtcaaagaa gatttctgta
    26341 tctggtccag aaggtcccgc accgatttcc cagaagttgt cctcaattgg aatcaagtga
    26401 cttggatcca ctcccacttc aatccagcgg ttgtaagaat ctttatcgtc tggatagtag
    26461 gtcatgtaaa gtttttcagc agggaaatca aaccattcag ggcttgtcaa aagctcataa
    26521 gcccaagtga tagcttcgtc acggaagtaa tccccgatag agaagttccc cagcatttca
    26581 aacatggtat ggtgacgcgc ggtcttccct acgttttcga tgtcgttggt acggatagcc
    26641 ttttgggcat tggtaataca tggattttca gggataatgg tcccgtcaaa gtatttctta
    26701 agggttgcta ccccagagtt gatccacaaa agagttgggt catttacagg aaccaaactt
    26761 actgatggtt ctactgagtg acctttggtc gcccagaaat caagccacat ttggcgtact
    26821 tgtgcactag atagttgttt catattgtct ccttattcac ttgtttaatg tgattggctt
    26881 tccagcattt ccacatagtc aatcgcgaca cagagggaaa tgactaggtc tgcataagcg
    26941 tcttcaagaa ccgttacggt ataggtagag gtcagatgga agagttcctt cttaatttcc
    27001 gcaatcaact gatcgcgatc atccagcaat ttgaaattca aatcccagat attgccctcg
    27061 atacgaagac ctagattatc aaactcatac ttatctcgcc agaaggtcaa cttcttacga
    27121 atgacaaaac tcgagccatc ccgaagctga atctcaaaac gaggaagcaa ggtcaagatt
    27181 tctttactaa tctcactgac ttgttcacca gccgcatcat agatggtaaa ggttttagga
    27241 atcttaaaaa atgatccctc cacctgatag gcaatttctc ccctgtcatt cttgatagcg
    27301 aagcgttcgc ctccaagacg aaacttttgt ttgacaagaa atgttttcat caacacctcc
    27361 aaaaatcaaa agacaagctc atatcacgaa gggcgaaaaa ccgcggtacc accttcattc
    27421 aatgaacttg tcattctctt gttcttatgc aattgtatga ttgagtagca tgacttccta
    27481 gcttagatgg ctcgcagcac cgccatttct ctggactaag acaagtgaaa atcaattctc
    27541 aactttctta ttatatcgtt tttttaatct tgcgtcaact ggaaatgatc tccgttgaat
    27601 tagaccaatt ccctacatct ctgattactt tttcaggata tattttttct tactgccatt
    27661 tttcttttta tcccaaattt tcatattact aaacacagct actagaatat ttccaaatat
    27721 aaaggtgcct atcacccaat atatggactc agttgttagg tattgtcgat ccaagccatc
    27781 ctttaaatgg aatagtataa cagtttggtt aacaatcata aaggttggcc agaaactttt
    27841 tttgaaaaaa gtagacattt tcattatttg ttgccgcttt ctgtaaggtt aatactcaat
    27901 aaaaatcaaa aagcaaacta ggaagctagc ctcaagctgt acttgagtac ggcaaggcaa
    27961 cgctgacgtg gtttgaagag tataggctta gtatactact aggcaagcaa ataagcaaat
    28021 aaacaaataa acaactagaa tagaaaaaga tagggctcta aaaactgact tctattcctt
    28081 aaaaacgaac cagcttgact gattcgtctt cttacgttta tctcctactt ccgatacatt
    28141 ttaaactgta ggaagaggtc gctatatttc cctgtccatt tatggtcaaa tttctcataa
    28201 acttctaggt gtttcatggt ttcaacatcg ggatagaagg ccttatcttc ctttgtttcc
    28261 tctgggagca attccttcgc tggtaggttt ggtgttgaat agccgacata ctccgcattt
    28321 tggagagcat tttcaggttt caacataaag ttgataaagg cataggctga gttttggttt
    28381 ttaactgttt tgggaatgac catattgtca aaccaaagat tgctggcctc tgtcggtacc
    28441 acataacgta gattttcatt tttttctaac atttggctgg cttcaccaga gaaggtcacg
    28501 ccgattgcaa cattattctg aatcatatag cccttcatct cgtccgcaac gatagccttg
    28561 atatttggag tcagtttgta gagcttatcc actgtctctt ccaactgctg cagatccttg
    28621 gagttgaggc tgtagccgag ggaattgagt cctagtccca gcacctcacg cgccccatca
    28681 aagagcatga tagaattctt atactccggc ttccaaaggt catcccaatg ctcaggcgct
    28741 tcatctacca tggtttcgtt gtagacaatt cctaaggttc cccagaagta agggatggag
    28801 aatttattac ctgggtcaaa ggactggttg agaaactctg gtccgatatt ttcgattcct
    28861 ttaatttttg aataatcaag cggaaccaag aggtcttcgt ccttcatctt gttaatcatg
    28921 tattcacttg gaatggcaat atcgtaggtc gttccaccct gctttatctt agtgtacatg
    28981 gcttcgttgg agtcaaaagt ctcgtactga acttgaattc ctgtttcttc tgtaaactga
    29041 gtcaagagtt caggatcgat atagtctccc cagttataga taaccaattt ttgactatct
    29101 cgactattga ttttactatc taaatgagtc gcaattcccc acaagacaag gataatcgct
    29161 gcaattcctg ctaaaaatga atagattttt ttcatgcttg ctcctccttc tcacgagaga
    29221 taaagtaata acctacaact aggataatac taaagagaaa gactagagca gacagggcat
    29281 tgatttctaa ggaaatcccc ttgcgagcac gagagtaaat ctcgactgat agggttgaaa
    29341 agccatttcc tgttacaaag aaggtcacgg caaaatcatc cagcgaatag gtgaaggcca
    29401 tgaagtaacc tgcaatgata gacggagtca ggtaaggaag catgatttcc ttaaacatct
    29461 gaaattgact agctcccaag tcataggccg catgaatcat gtcgccattc atttccttga
    29521 gtcgaggcaa gaccatcaag accacgatag gaatggagaa ggccacgtga ctagatagaa
    29581 cggtcaaaaa gccaagtgaa aacttgagtt gggtaaagag aatcaagaag ctagcaccaa
    29641 tcataacgtc aggcgcaacc atgaggatat tattgagtga tagaaaggct tcttggtatt
    29701 tcttacgaga ctggtagatg taaatggcac caaaagtccc gataatggtc gctatcaagg
    29761 ctgataggaa ggccaagaaa aatgtctgag ccaaaatcag catgagtctc ccatctccaa
    29821 acatggtttc aaagtgagtc cagctaaaac ctgtaaagct attcatatca tcaccagcat
    29881 taaaggcata gccaatcaag taaaaaatcg gcaggtagag gaccagaaag accagtccca
    29941 gataaaggtt ggcaaatttt ttcatcgttc tctcctttcc ttggtcaccc acatggtgat
    30001 gaacatggtc aggatgagaa tcacaccgat ggttgaaccc ataccatagt tgtcattggt
    30061 tagaaaattc tgctcaatag ccgtccccaa ggtgataacg cggttcccac caatcaaacg
    30121 ggtcagcatg aagagactca aacttgggat aaagaccgac tgaaccccac ttcgcacacc
    30181 gttcatagat agagggaaga tgacatgacg gaaggtctcc cacttagttg caccaaggtc
    30241 gtaactagca ttgatgagat tattatccat atcgtctaag acattgaaaa tcggcaaaat
    30301 cataaagggg agctcgatgt agcttgcgac aaagataaag gaaaaatcgg taaaaagcaa
    30361 ctgttgtgaa ccaattccga taaattccaa gaattggtta atagagccat tttgaccaaa
    30421 aatcccgata aaagcatagg ctttaaggag caaattgatc caggtaggaa ggataatcag
    30481 catgagccag agttgacggt gcttgagacg ggtcaaaaag agggctgttg gatagctgat
    30541 aagcaaggtc acaaaggtca caatccctgc ataaagcact gagttgaaac tcattttgag
    30601 gtaggtcaag ttttgtgacg caaagtaaga tttataattt tctaaactaa actggccttc
    30661 aatgttgaaa aaggattgtc cgaaaatcaa gaccaagggt gccaatacaa agagggcaat
    30721 ccaaagcatg tagggcacta caaagagttt agagcttgtt ttcttcatct ctttcctcct
    30781 cgatcgcatt gatcagacct gcttcttgct cttcgatttc cacgtattct tcgatacgag
    30841 catcgaactc ttcttcggtt tcattgagac gcatgatgtg gatgtcttct gattcaaagt
    30901 ccagaccgat ttcctcaccc acgatggcct tacgggttga gtggatcatc cattcatttc
    30961 caagttcgtc ataggcgata atttcataat gaactccacg gaagagctgg gtgtcgacct
    31021 taacttggag tttgccttct tcaggaaggg taatgcgcaa gtcctctgga cgaataacga
    31081 cctcaacagg ttcatttggc ttcatcccac catcaaccgc ttcaaagcgt ttgccgttaa
    31141 attcgaccaa gtagtcctca atcatggtac ctggcaagat gtttgactcc ccgataaagg
    31201 tggcaacaaa gtggttgatt ggctcatcgt agatgtccac aggggttcca gactggacaa
    31261 tctcgccatc attcataacg aaaatccagt cactcatggc aagagcttct tcctgatcgt
    31321 gagtgacaaa gacaaaggta atgcccaatc gttgttgtaa ttcacgcaat tcgtactgca
    31381 tgtctgttct caatttcaag tccagcgctg ataaaggctc gtccaacaag accacacggg
    31441 gttggttgat gatagcacgg gcgatggcca cacgctgacg ttgtcctcca gaaagtttgc
    31501 ggatggaacg tttttcataa ccttccaact gaaccatctt gagaacttcc gctacacgct
    31561 gctcgatttc tttcttatca attttacgca agcgaagtgg aaaggcaaca ttttcaaaca
    31621 cattcatatg tgggaacaag gcataggatt ggaagacggt atgtacgtcg cgcttgttgg
    31681 ttggaatatc attgatacga acaccgtcta gcatgatatc tcctgtcgtc gcatccagta
    31741 aacctgcaat aatgtttagg atagttgatt tccccgaacc agatgcacct agaagggtgt
    31801 agaatttccc ttcttccaac tcaaagttga tgtctttgag aaccttggtg ttgctgtctt
    31861 caaaaacttt agagacgttt ttgaattcga taattggttt tttcaattgg cataaattcc
    31921 ttctttttca tagattaacc gatcggggct ctgtcaggtc cccactacct cttgcaggga
    31981 gtaaaaccac ctgcatacat cttcgctacc gataggcttt cacccccttt ccatgacata
    32041 gcagcagctt ttcaaataca gcttcctact tgctttcacc caagatccgg acttctcttt
    32101 caagcgtaat acctgagtgt tccttgactt tttcgataac cgattggatc aagtcctcgt
    32161 agtctttggc cgttccatct gcgacattga tcataaatcc tgcatgcttt tctgacactt
    32221 ctacgccacc gatacgatag cctttcaagc cagcttctga aattaactga cctgcaaaat
    32281 gcccgactgg acgcttaaag accgagccac aagatgggta ttccaaaggt tgcttgagtt
    32341 cacgtaggtg cgtcaagcgg tccatttcct gcttgataac ctgatgggtt cctggggcta
    32401 gggcaaattt aactgacaag acaactgcac cagactcctg aatagctgaa tggcggtaac
    32461 caaaagccaa gtctttagca gacagggttt cgatttctcc atccttggtc aagaccttac
    32521 aagactgcaa gatgtgagca atctcgccac cataggcacc cgcattcata aagacagcac
    32581 cgccaacgct tcctggaata ccacaagcaa actcaaagcc agtcaaacta tgacggaggg
    32641 caatgcgagt tgtttcaatc aagttagccc cagcttctgc ttcaatggta tagccatcaa
    32701 cagaaacgtt attgagcttg tcacacaaga tgacaaatcc acgaatccca ccatcacgaa
    32761 cgatgatatt gcttgcattg ccaagaacca tccaagggat attttcttgg ttggcaaatt
    32821 tcacaaggcg cgccaactca aaacgatttc gtggaaagac caaataatca gcctctccac
    32881 ctacttttgt ataactatag ctatgcaagg gttccttaaa acggatatca attccttcta
    32941 agatttcaag cattttttct cttacagaca tgtcactctt ccttttacaa aattcattcc
    33001 attataccat ttttagagac atttgacgac cataaaaata ccttgtttgg attttgcata
    33061 agaaaaagag gttcccccct ttttatgatt ttttacaaaa gatttccttg gttccatagg
    33121 cgaccagaac gagctccagt gctagaatca cttcaaccaa gactggattt gtcaaccagc
    33181 ctacttggaa aagagatggt gccagatcaa agaaggcatg caagccatag gctgctagga
    33241 gataaatcca tttcttctgg cgaacagctt ggtaaaccca aactgtcaaa agtaattgga
    33301 aaccaagcgc caagattcgc tcaaaaccaa gcaaataaat ctgccagacc gaaagtgact
    33361 gaatggtttt taacatattt tcagacagta attgcataac ctgtggattc tgagtttgaa
    33421 ctgccgaaag aacgatgtaa agattgagta aactaataag gcctagaaaa atcaactcca
    33481 agccaccatg ccctaggcca taggccaagg catctgcctt ttccaaactt ctctttttct
    33541 ccaaccattt gaagaaaaca agacgagccg tttcctcaaa aaatgctgcc atggctaggc
    33601 catagataat atagataagc ggatgatctt gcaagagggc aatactaccg tctttttgag
    33661 ggtgcaaaat caagatatgc accagttttt ccaaaatctg cgaagagaca aagaaagcga
    33721 ctgcacccaa gcccaagaca gctagattaa tctggtattt ctttttggca aaccaaatgc
    33781 ttcctatcag aaaagctagc aacagcaaca tggtaataat gatatgaatg gtcattttct
    33841 tctcctattc tgccttttca atatcttttt tcatctcgtc aacattgaac ttagcaaaca
    33901 agtattgacg gtcttggact gggaaacgtt ggtccaactg gtcaactgct cccacctcga
    33961 taatgccttc cttgatgaca aaatccatga catgtccacc gaaggtcaaa tcatctgata
    34021 tgaagtgcag atggtagcct gccacactga ccccatggaa aatctcaggc gtccagaaac
    34081 caacaatagt ccccgcaaca ttgtcacgac tatattccgg ttgatgggtt gcgacatcag
    34141 caaacttagt atcgggtgtt gacttaggaa tcatacgcac atgcatatgt gaaaattctc
    34201 cccgaatctt gatagaacgg aaaagatttt ccccatcata ataagactca attcgttctt
    34261 tcaattcctt gtctgtcatc tcaaagcgct ggcggaaaat gacctctgcc tgatgcggta
    34321 ccactgcagc gtaaggaata agggcatctg gtgacacttc cacaatttct ggctggtctc
    34381 ctgacccttt ggcctgataa gccttgccat ccaagacaat caattcccca tcaatagaat
    34441 ccaaggttcc caaaccaagg tcaccatgct ctagcaattc tcccactgtc atggtaccac
    34501 cataaaggcc agccatcaag gctccaagag tattgtattg aaataatttc actggttcct
    34561 gcacgttctt atccattcac tttcttgtct gttattctat aaatcttact cctaagtata
    34621 ccacatttgc ccctagatgt gaacgagaga aacgctctag acattgccaa gaaggaaaaa
    34681 aaagggtaca atgtaacaaa atcaagggag gtctggaatg aagaaacaaa gcaagtacaa
    34741 agaggtcgtt tcctatctga aaaatggtat cgagtctgga cgatttccga cgggtagtcg
    34801 cctgccttct atccgtcaac tgagccttga ctttcactgt agcaaggaca ccattcaacg
    34861 agccctgctg gaattacggc acgaacaata cctctatgcc aagccccaga gtggctacta
    34921 tgtcctagaa caagggcaac accaggacct agaaatcgag gttaccgacg aacatgccag
    34981 tgcctatgac gatttccgac tctgtgtcaa tgaaaccttg attggccgag aaaactacct
    35041 cttcaactac tatgataatc aagaaggatt agaagaccta agacaatcca ttcacaaact
    35101 cctctttgag caagctctct actgcaaggc taaccaacta gtactgactt ctggaaccca
    35161 acaagccttg tttatcctct ctcaaatatc ctttcctagc caagccaagg aaatcttggt
    35221 ggaacagcca acctaccatc ggatgaatcg cctcttgatt gcacaggggc tggactatca
    35281 aacgattgaa cgaggcattg atgggattga cctgaaggag ctggagcgac acttcaagac
    35341 aggaaaaatt aagtttttct acaccattcc ccgatttcac tatcctctgg gacattccta
    35401 ttctgagcaa gacaaacgat ccattcttaa cttagctgcc aagtatgatg tctatatcgt
    35461 agaagacgat tatctgggtg atttggactc caagaagggc caaaccttcc actatcttga
    35521 tacagaggag catgtcattt atatcaagtc cttctcgacc agcctttttc ctgcccttcg
    35581 tattacagca ctcattcttc caaatgctat caaagaagca tttgtggcct acaaaaatat
    35641 cctagactac gacagcaacc tcattatgca aaaggccctg tcactctata ttgacagtca
    35701 attgtttgaa aaaaatcgtt tggctcgctt gaccaatcat gaatcttacc aaaaacaaat
    35761 cgaggaaagg ataactaaaa caccttgtcc ccttcctcat tatcccctac acgatggttt
    35821 attgctagac ctgagacagt atcctaaaat cgccagtctc aaacacagtc aaccgggctt
    35881 ggacttcttt gaagaggcct atttaagtac ctgtccttat caatttgcca aggtgtccct
    35941 agacaatctg gaaaatgttt taaactattt aaaagcagaa ttggaatgac atccaactct
    36001 gctttttctt attcttcaac ttcagttaga cttgctgctt tttcaagata gctttggtaa
    36061 attccttcat ccttaagttt ttggatgacc ttgtctacca cttctttcaa atcatcacta
    36121 ttttttctaa gagcaacggc attggcgtcg ccgtccttca tcttcaagct gacagttgcg
    36181 acagctaagc cagcgttttt agcagcataa ctaagtgcaa caggctcatc catatgaaca
    36241 gcatctactt ttccagcctg caattcattg actgcttcac ccatattagt tagggaagtt
    36301 aattgagctt ttggcaattg ttccttgacc attgattctg gaacagtccc tttttgggct
    36361 gcaatattag cactttctag gctagttaaa tccttgtatt tttccacatc agccttacga
    36421 accaagaaac taatcttgtt ttcatagtat gggattgaaa aatcaaagac ttcttttctc
    36481 tcgtcagtag cactaattcc tgcaactgct aggtcagcct taccagtttg aagactggtc
    36541 aaaacattgt caaaactcat gcttgagatt tccaacttaa ccccaagttc atcagcgata
    36601 gcctgagcca tgtcgatgtc tgcaccgact acctggttct ttccatcaac caatgattga
    36661 aattcaaagg gtgcatagtc aggactggtt gccacaacta atttcccctt ttgcttaatt
    36721 gcctcaacag ctgactgaga accattagaa cctgactggc aagctactaa gaagaaactt
    36781 gcaagaaaat tacataaaac aaatatccat ttttttgatt tcataaataa acaacctctc
    36841 tgttaatttt gtataattat aacgatatcc aagttacttg tcaagtgttt tttaaatttt
    36901 tatctcaaaa atattttttc gttcaaaaaa aggagccatc agttgatttc aagctccttt
    36961 ttatacagaa ttaaactatt ttatagttcg acaatcttac ctgtttcaaa gtagacaacc
    37021 cattcacaga tatttttagc atagtcaccg atacgctcca agtaggaaat aacttggaaa
    37081 taatcacgac ccgtaacaat ggcttctgga tttttcttaa tctcttcagt cgcaaggtca
    37141 cggatagttt caaaatagtg gttaatttgc tcatccatgg aggccacccg gtatgcgtcg
    37201 tcaacagaac cattaagata aagatcaagt gctgcttcaa caacgctttt aacttcacgt
    37261 cccatttttt taatttcttc ctctacagct ggaatacgtt cttccccctt catacggatg
    37321 gttgcctggg caatggctac agcgtgatcc cccatacgct ccacatctga tacagcctta
    37381 aggacagtca agactgtacg caaatcttga gagactggtt gttggagtgc gatcatttca
    37441 aatgatttct tttccagttt cacttcgtat tcatttactt ctgcatcatc ttcgatgacc
    37501 tcttttgcca ggtcacggtc atgcgtgaca aaagcacgta ccgtacgatt gatttgtgag
    37561 agcacttctt gtcccatagc gtagaactgg ttatgtaatt tctctaaatc ttcttcaaat
    37621 tgagatcgta acatctttca tctccttatc caaattttcc tgtaatatag tcttccgttt
    37681 ccttgtgttg gggatcaagg aacatctgct tggtatcatt aaattcaatc aaatctccat
    37741 ctaggaaaaa tcctgtctta tcagagatac gtgaagcttg ctgcatggaa cgggttacca
    37801 gaagcatggt gtacttgtct tttagaccat acaaggtttc ctcaatttta ccagctgaaa
    37861 tcggatccaa agccgaagtt ggctcatcca agaggatgat tttaggacta gttgccaaga
    37921 cacgggccac gcagacacgc tgctgttgac cacctgacaa tccaatagct gaatcatata
    37981 gacgatcctt gacctcatcc cagatagagg caccttgcaa ggctttttct acggcttcat
    38041 ccagaacctg cttatcctta attccattga tacgaagccc gtagacaaca ttctcataga
    38101 tagtcatagg gaaaggatta ggttgttgga aaaccattcc gatttcctta cgtaattcaa
    38161 ccgtatctgt acgcggactg tagatgttgt gaccattgta caccacggat ccagttgtgg
    38221 tcacctctgg attgagatct cccatgcggt tgagagactt gaggagggtt gacttccctg
    38281 atccagatgg accaatcaag gctgtaattt ccttaggttg gaaagatagg gaaacactat
    38341 tcaaagcctt ctttttatta taataaacgg acaggtctga tacctgtaaa atcgcatctg
    38401 tcatacggtt tcctttctaa ccaaagtgac cagatacata gtcattggtg gactgtagct
    38461 tggcattttg gaaaatagtt gcagtcttgt catactcaat caaatcaccc aagtaaaaga
    38521 agcctgtata gtcacttgca cgagcagcct gctgcatatt atgcgttaca atgatgatgg
    38581 taaagttttt cttgagctca aacatggtct cttctagttg catggtcgca atcggatcca
    38641 aggctgaggc tggctcatcc attaagagga tatctggctt aacagagatg gcacgagcga
    38701 tacagagacg ttgttgctga ccacctgata aggtcaaggc tgacttgtgg agatcgtctt
    38761 taacctgatc ccagagggca gcctgacgaa gggaggtttc tacgatttca tctaggactt
    38821 gcttatcctt aactccagca cgttcatgcg caaaggtaat attacggtaa attgacttag
    38881 caaatggatt ggggcgttga aaaaccattc caatgtgttt acgcatttca taaacgttga
    38941 tttctggacg gttgacatca attccacgat agagaatctg cccagttact ttagcaatat
    39001 caatggtatc attcatgcga ttgagactgc gtaagtaggt agatttcccc gatcccgacg
    39061 gaccaatcaa agctgtaatt ttatttcttt caaattgcat atcaatcccc ttaatggatt
    39121 catttttacc atagtaaaca tggacatcct tagtagaaag ggctactttt tcttcaggaa
    39181 aggtaaggat atgcttctca tcccagttat atgttgacat ggcttctcct ttaggcagcg
    39241 gttaatttct tgtgtagata gcttccgaac ttacgagctc caaagttaaa aatcaggata
    39301 aagatcagga gcacagcggc agaacctgct gatacaatgg ttccatctgg aatagtgcct
    39361 tcactattga ctttccagat atggacagcc aaggtttctg cttgacggaa gatagagatg
    39421 gggctagtca cactgaggat attccagtta gaccagtcaa gagctggcgc cgattgccct
    39481 gctgtataga tcagagctgc agcttcgcca aagatacgac cagatgccaa gacgacaccc
    39541 gttacaatac ctggaagcgc ttctggaata acaacatgaa ccactgtctc ccagcgagaa
    39601 atcccaagag ccagaccagc ctcacgttgg gtatggtgaa cgtgtttcaa actatcctct
    39661 acattacgcg tcatctgagg caagttaaag actgtcaagg ccaaggcacc tgaaatgatt
    39721 gaaaacccat actcaaactg gactacaaag atcaagtaac caaagagacc caccaccact
    39781 gatggtaaag aggacaagat ttcaatacaa gtccgcacaa agttggtaac aggacctttt
    39841 ttagcatatt cagccaagta aatcccagct cccatagaaa gaggtacaga aataatcaag
    39901 gtaatgacca ataggaaaaa ggaattgtaa agctgaatgc caatcccacc acctgcttga
    39961 aaagcagaag accttccagt caagaaagac caagagatat ggggcaagcc ccgaaccaag
    40021 atatagagaa ttaaggaagc caagattgtc acaatgatgc tagcaatcgt atagaggaca
    40081 gctgttgcaa gtttatctaa tttcttagcg cgcataattt ttctttcctc tttctttcgt
    40141 aatcaattta atcacactgt taaaaactaa actcatcaag agcagtacca aggccagtga
    40201 ccagagaaca ttattattta cagttcccat gacagtgttc ccaattccca tagttaatat
    40261 agaagttaaa gttgcagctg gtgtggtcaa ggaagttggg ataacagctg agtttccgac
    40321 aaccatctgg atagctaaag cctcaccaaa ggcacgcgcc atcccaaaga ccactgcagt
    40381 gaaaatacca gaacgggccg ccttcaagat cacacgccag atagtctgcc agcgagtggc
    40441 tcccatagcg aaactggcct cacgataata acgaggaacc gcacgcaagc tatccgttgt
    40501 cataaaggtt acggtcggca aaatcatgac aaagaggacg gaaatccctg acaaaatccc
    40561 aaaaccagtc ccaccaaaga cactgcgaac aaagggaacg acgacttgca agccaataaa
    40621 tccgtacact actgaaggaa tcccaaccag gagttcaata gctggttgca aaatcttcgc
    40681 cccttttggt gatacttcgg tcataaaaac tgctgcacca atagcaaagg gtgttgcgat
    40741 aagggctgag agaatggtaa cgataaagga acccaaaatc ataggaaggg caccaaattc
    40801 tttactagaa ggattccaag ttcctcccaa aagaaagtca aagatattca caccattgac
    40861 aaagaaggtc gacaagcctt tttgcgctac gaaaaccaaa atcatggcca caaggatgac
    40921 tatcaaagaa agacaggcaa aggtcaaacc ttttcctaat ttctccagac gagaattctt
    40981 tgatggaagc aacattttct tagctaattc ttcttgattc attattgtct cccttccaac
    41041 actgtcacag ttccggcagc atctttttca accttcattt ccttaatcgg aatatacttc
    41101 aatcctttga caatcccttc ttgggtctca tccgagagaa caaaattgag aaattctgca
    41161 gccaactcat tgggctgccc caatgtatac atatgctcat aagaccacaa gggccaatta
    41221 ttgctactta tattttctgg acttaagtca tagccattca acttcatgct tttgaccgaa
    41281 tcatctatat aggtaagaga taaataagag atagctcctg gactttttga tacgattgat
    41341 tttaccgctc catttgaatc ctgctcctga ctttgcatgg cagactgacc ttccataatg
    41401 acagtatcaa aggtagcacg agaaccagag ccggctgccc gattgataac agagatgggt
    41461 aagtccttac caccaacctc tttccaattg gttacctcac ctatgaagat ttgacgaagt
    41521 tgctctgtcg ttaggttatc aacatcaacc tccttattga caatcagagc caagccagct
    41581 accgcgacct tgtggtcaac aagagcagaa gcatcaattc cgtctttttc ctcagcaaat
    41641 acatctgagt ttcctatatc aactgcccca gactgaacct gggacaagcc tgtaccagaa
    41701 cctccccctt ggacattgac cgtttttcca acatggatcg tgccaaattc atctgccgct
    41761 acttcaacca agggttgcaa ggcagttgag ccaacagccg ttatggattc tccacgatca
    41821 atccagctag cacagcctac taaacaagcc gtcagccaaa aagcgataag agacagagca
    41881 agcttttttc tttttttcac tgtttttctc ctcgaaaata attatgaata ctgtgaattt
    41941 tttaagtagt tctttatgag ttgacgcatg aattcttacc aaatttctgc gcaattgatt
    42001 atttatataa tataggctat attactcttt cctaacctcc ttttttcata tgtggataaa
    42061 atctcttgtc tatcccttcc cccattgtca cccattatag tcatttcgtg tctctttttc
    42121 ccctttttaa tgcaagggaa attactctcc ttagatgata atccaaaagc tagaaaggta
    42181 tctcaaacct ctctactctc ccagactagt ttacaactaa aaggaaaaga ttctatttta
    42241 tgagaaatct agtttacaag cggtaagaac gctaataact aaacttcttg tactctttga
    42301 aaatctcttc aaaccagtgt tttgagctat ctatggctag cttcctagtt tgctctttga
    42361 ttttcattga gtagtaaaac tacatgtaat ggcaatcaag atatcaagaa tcatcctact
    42421 aaaaaaatcc atactttcac tataacatag aataagatat ttgactagca ttttcatttg
    42481 aatctgaggc cttttggaaa ataatttttc aaaacatttc cagtaacctt tgcaaagccc
    42541 aagccattgc ctttaaccaa aacttggtac caaccatttg gcagactttc tgccagctga
    42601 acgatttctc cagccgcata cttgacaaac gcttcttggc caatttcaac cgactgttcg
    42661 acctgactcg gtttcaaggc taaaccaaga gcgaaactgg gctcaaagcg tttcttctta
    42721 aaagtgccca gatgcagtcc attgcgagca atcttgagct tccctaaatc tggcaaaagt
    42781 tctggcaaga gataaagctg gtctccaaaa gtctgcaaga tacccggtag attgaccttc
    42841 aaatggtttt gggcaaattc ctgccacaag gcaacttgtt cacggctgag gttactctta
    42901 cttgccttaa atttaggagc tggattgtta cccttaaact gtagatgggc aacaaactga
    42961 ccctctccct taaactgatg agggtacatc cgagccgttt ctggcaggtc aataccagct
    43021 accattccat tgatatgctc tactggcaac aagtcaaaat catactcttc cagcaaccaa
    43081 ttgacaatct cttcgttttc ctcgggtgcc caggtacagg tcgaataaac cagacgacca
    43141 ccttcagcta acatggtcac tgcatcctcc agaatttctc tttgcaagct agcacattga
    43201 ctcggataat ctaagctcca atagtccata gcatcaggtt gcttacgaaa cattccttca
    43261 ccagagcaag gggcatcaag aacgattaag tcaaaatagc ctttaaagac cttgaccaag
    43321 cggtcggcag attcattggt caccacgaca tttgtcgctc caaaacgctc catgttttca
    43381 accaaaatct tagcccgttt gcttgaaatt tcattggaaa caagtagccc ctcccctgct
    43441 agataggctg ccagttgagt tgatttgccc cccggtgcag cagccaagtc caagaccttc
    43501 ataccaggac tgggttgagc tacttgagcc accatttgag cagcaggttc ttgcgaataa
    43561 actaaacctg tagcatgctc aggcgatttc cctgaaacct tcccatagtg gccccaaggg
    43621 gtttgagtaa tggcatcaga aaaggaaagt tgctcttctt ttaagggatt gacccgaaag
    43681 gccgaaaccg cttcctcctc aaaagaggca agaaaatctc ttgcctcatc tcctagtatc
    43741 tctttatatt tttcaacaaa tccttctgga aattgcattt aagttctttt cctttcgtaa
    43801 atataggact gaatttcctc ctgcatctca agaggcacca tcatgaccgg ctgtctggtt
    43861 tgaaaatcag gagcttcacc aaaaagggtc acaacccgat agcccagact ttcccctaaa
    43921 atactagctg cggcataatc ccatggttgc agataagtga gataggtcaa caaacgccct
    43981 gacaaaatct tggcaaaact aatggccgca cttccataga cacgaacacc aagaaccgct
    44041 cggctcaaat cagccagccc ccattcattg gtttccagca taccactatt ccctgcaatg
    44101 agaaaatctc caagtggttt agttttaaaa ggagctaggg gcctatcatt tagacaaact
    44161 ggaaattccc caccaccgtg gtaacaatcc cctttgacca catcataaat cagaccaaac
    44221 tgtccctgac cattttcaaa ataagccatc ataacagcaa aatcttcctg ctgggctaca
    44281 aaattattgg taccatcaat gggatcaatg acccaaacct tgccctcttg aaccgaggct
    44341 cgcagacaac cttcttcagc acaaatctta tcctcaggat aacgggacaa aatctcacca
    44401 accaagagtt cctgaacttc tttgtccagt ctggtcacca aatctgttgg agaggacttg
    44461 gtttcaacac gcaagtcttc ctgcatatgg tcaagaatgt actgacctgc tttcttaaca
    44521 agctctttag caaattcaaa tttactttcc aagagaaatc tttccttccc ctttttcttt
    44581 ggcagcctga actgctcggt aaagtgaata gccactaacc gtttcaaatt ctcgtcccaa
    44641 acgtttctct tcgctcttgc ttggcacgac cgctttgaat cccttatagg agtccagtaa
    44701 ctttttagcc tctactttgc cttcataggc agcttcaaca tcattaaaaa aagaaagcac
    44761 tgaagcaagt tcttcagtgc tccacgacaa atctagtggg taactatact gtttgttcat
    44821 taactaatac cagctctcat tcttgcttct tttagttctt gcttacgata actacgaggg
    44881 agaaaagcac gaatctcatc ttcattaaaa ccgatttgca tacgcttggc atcaataata
    44941 attggacgac gcaaaagact aggatactgc tcaatcaaat gaagcaattc cgataccgaa
    45001 atactctcta catcaatatt caatttttga aaaatttttg aacgagttga aatgatgtca
    45061 tcagtaccat tttcggtcaa ggaaaggatg tgttgcaatt cttttcttgt taaaggactg
    45121 gtcataatat tgtgttccac aaagggaacc ttatgttttt ctaaccaggc cttagcctta
    45181 cgacatgatg tacagctcgg tgatagaaat agtgtaatca tgcttttctc ttcttatcta
    45241 tactttgcta cttctattat acaaaaaaat aaggcgcttg actagggatt tttagaaaaa
    45301 aagcctattt tttcaagaaa aataggctgt ttgcgaacga ttgacacaat tggatttggt
    45361 taattcactc ttaacgatgg ttttaaacga tatatatttt tatatatgca aattaaaaac
    45421 atctttcatt tcacttccta cgacttttca gacacagata gccaaagaag ctttcataga
    45481 gggcaaaaaa gaggaggaag gcatgaagaa agaaggtctc tggcaaaatc ataataacag
    45541 gatccttggc tggatcaaaa agccaggtat catctcccac aaagagaatt tgatggaaaa
    45601 gagtaaagaa ttggtcaaaa ccaatcaaaa ctcccccaag tccaatcatc acaggtaaga
    45661 ctactagagc caggagactt tttcgataaa gagacaaaaa gtcctttttc acaatcctat
    45721 tgacaaagac atagaaactt ggcagtgtca ctagagctac tagctgaacc aaatgaaaga
    45781 gattcttgac cactgcgaaa tggtgcagac cagctgctga cgaacgaaaa tcaggcatct
    45841 gtaagacctg actaaaagga ttggtcagat aattcatcaa gatatgaaaa ttgtattgaa
    45901 tggtttctgg ttttagatag actcgattcg ttaagtttag ccactgaatc tccataggat
    45961 agaaaatcca agccagataa atggtcagaa ggattgagag ggagaggaga aagagcatag
    46021 agccccaaaa ggtcaattta gttttcatca aaatcccact ccgcaaggct agaaaccaca
    46081 tgtgtcggtg cgattggcag gccagctact tcttctgcct tggtaaaacc tgtcgtcacc
    46141 aagagcgttg gaatgccatt gtcaatccca gcccggatat cagtcaaata attgtcccca
    46201 accatgatta actcttcacg ttccaaacct aagtgctcaa ccgccttgtc cataatgatg
    46261 gcatttggtt ttccgatata aaccggcttc actcgtgtcg ctacttcaag cagcgtaatc
    46321 agtgagccag cacctggcaa aagaccgcgt tccgtcggga tgttgaggtc aggattggtt
    46381 ccgataaaat gggcaccctt ttgaatagca agagttgctg tggcaaattt ttcatagtcg
    46441 acttgccaat ccagaccaac taccacgtag gcaggttttt ccttgtcttc cacataacca
    46501 gccgccttga tggcttcctt gagtcctgct tctccgacga catagacggt cttttcaagc
    46561 cccaaatcat tcatatagtc gatggttgcc aaagtcgctg tgtagacagt cgataggggc
    46621 gtatcgatat taaaattctg agccaacatc tccttaacac tctctggagt gcgggttgta
    46681 ttgttggtta caaagagata gggaatgtcc cgcttttgca attcatgaac aaaagtctct
    46741 ccagcaggga ttcggtcttt ccccttataa atggttccgt ctaaatcaat taaatagcct
    46801 ttatatttca tctatttctc cctaagcctt ttttatttct tgccaagtaa tgattgcttg
    46861 ggcattgata accccatcac ttgtaatttc atgcttgctt tccagtccag tccgttcaac
    46921 agccgatgta atcaccccac ctggtcgaac ttccttgaca tacttgaggt tgattttctt
    46981 gggaatatag tgggtcaaaa aatccgctcc catgacctca aaaatccagt ccaagtattt
    47041 actgttattg acatgaccat tcatatccaa gtcgtaaaaa cgaacatggt aatccttgct
    47101 gatcggttct tccaaggact catacttcgg tccacggata agttttttat caaaatcaga
    47161 ctggtaagga gccacaatct caggttcaac aacatggact tttcgactgt cgcggtccat
    47221 gagaacaaag gtcgccatca tgtggatgag ctcctgctcc gcttcattat aaatagtaaa
    47281 gcgacggtag caaaaaagtc gattgtagct caaggcttcc gtttcgatgg taatttcttc
    47341 cgcaaaacga ggcaaacgaa ccacctcaat atcatattct acgataatcc agaccagatt
    47401 atattcttcc aaaatggcct tatcactaac tcccagttca atcgactgca tccctgaaac
    47461 ttgcagtgac agcaaaatca catctggaag tttgatatga ccgttcatat cagccatatc
    47521 aaaaggaatt ttcattttca tttgataagt taagcccatg atcctactcc aaaataaatc
    47581 gttctgctac agtatctccc aaaaagagac ctctctttgt catgcgaacg tggtcaccct
    47641 caatctgcat gaggccttgt tgaaccaaat ctctgacaat ttctccataa agtccagcaa
    47701 aagactgtcc aaatttttcc tcaaatcgcg ccatggaaac cccggatttc ttgcggagtc
    47761 ccaagaacat ttcttcttcc atttgctcct tttgactcag gtgatcttct gtaatacaag
    47821 cattgccttc ctcaaccgca ctgagataat gacgaatggg accatgattt ttatagcgta
    47881 ctccattgac ataaccagat gcccctgcac caataccata gtattcagca ttgtcccagt
    47941 acatgagatt gtgacgactt tcaaaaccgg gtttggagaa attagaaatc tcataatgct
    48001 caaaacccgc tcgctccagc tctgcaatga tgtactcaaa catctccgct tctagttcct
    48061 ccttaggcag aggcaatttc ccacgtcgca tccggttcat aaagaccgta tggttttcta
    48121 aaatcaaact atacaaactc atgtggggaa tatccagtcc aatggcttta gccacatttt
    48181 cctttacttg ctccatggtc tgaccaggca gagcataaat caaatcaatg gagatgttgt
    48241 caaaaccagc cagtttcaga cgatcgatat tttcataaat atccttctcc aaatgactgc
    48301 gcccaatctt tttcaacatc ttatcatcaa aggtctggac acctagcgaa acacgattga
    48361 cagccgaatt tttcaaaaca gctatcttat ccgcatccaa atcgcctgga ttggcttcaa
    48421 tggtcaactc ttccaagaca gacaagtcca agtttttagt caagccattc agtaacacct
    48481 ccagttgcgg agccgacagg gctgtcggtg ttccaccacc gatataaagg gttgacaact
    48541 tttcaatatc ataagaacga aactcttcca gcagatgctc taaatagctg tcgactggct
    48601 gatttttgat gaagaccttt gaaaaatcac aataataaca aatctgggta caaaatggga
    48661 tgtgcacata ggctgacgtt ggttttttct gcatagtaat tattatacca caaagactag
    48721 attccagata aaaatcacca tccccagata catagtccgt ccggagatgg tgatggttta
    48781 ttcttctgtt atatcaatca caatctcttc tgagtcatca agagcttcgg ctttttcttg
    48841 ccattgttcc ttgagattat ttaattgatt ttttgatgct tctgtcgctt gaaaagcata
    48901 ggatttagct tgagcaagta tactgtccac agtgatttca cctgactcaa cctgttcttt
    48961 tgttttcaga acaaaatctg tagcctgctc cttaacttct gtcagttttt cacagacttg
    49021 ctccttggca tactccggat cttctctcaa atcatctaga aaatcttgag cctgactgca
    49081 aacttgtttg cccttatcac ttgttaaaaa caaggcaaga gctgcacctg aaaccgttcc
    49141 taaaaggatt gaggataatt tacccataag gattctcctt ttttattttt tgaaaaattt
    49201 acttgcaaga cgaagagctg acagacttgc accagtcttg agtgtttttg aaccagctga
    49261 tgaagctttc ttgctcaaga cacgcgcatg gtcattgagg tctgaaacag atagagataa
    49321 atctgcaaca gcactgaaga gtggatcaat cgtagccacc ttgacattga tatcatctgc
    49381 caagacattg accttagcca acaactcatt ggtgtgatgc aaggtcacat ccacatctga
    49441 agtcaaggtt ttaatcgtct tttctgtttc atcgatgaca cgaccaagct tttgtacagt
    49501 aatgatcaga tagaccaaaa agacaatcaa agctagggca acaagaatat atgcaacttc
    49561 taacatttat ttttcctcct ctgtaatata gtaaggggcc ttctttcgat tttgataaat
    49621 aacgatcatt ataccgagac cgataaggac aactgacagc cattgggaca ctcgaaggct
    49681 gaagaacatg agactatctg ttcgcatacc ttcgatgacc atacgaccga aaccatacca
    49741 aatcaagtaa aaggccgtga tatgacctcg tctgagactc ttccatttcc gtctaaaaat
    49801 cagaatcaaa gcaaagccaa gcagattcca tagagactca taaaggaaag tcggttgacg
    49861 gtagctcccc tcaatataca tctggtcacg gataaagcca ggtagataat ccagattatc
    49921 cactgttgca ccataagctt cttggttaaa gaaattaccc caacgcccca aactttgagc
    49981 aatcataacg ctaggcgccg caatatctag aaaatcccaa gtattgatga gtttacggtc
    50041 agcaaagata tagagcacaa gagccccagt tatcaaacca ccgtaaatgg ccaaaccacc
    50101 attccaaatg gcaaaaatct ctcctaaatt ctgactatag taatcaaatc ggaaaataac
    50161 atagtagaga cgagctccta aaatagccaa gggaaaggct actaagataa aatctaaaat
    50221 atcgtctggt atgatcttct ttctaggtgc ttctttcatg gtcaaataaa ccgcaagaat
    50281 caagcctgtc acaatacata aggcatacca acgaatggct aggggtccta gttgaatagc
    50341 aattggatca agcattttgc acctcatttc gagcaatgag acttgtcagt cgttcgtcga
    50401 acaaacgggt cgcatcaaag cccatttcct tggcacgata attcatggca gctgcctcaa
    50461 tcacaacaga gatattacga cctgttttaa ctggaatacg aatacgagga atggctacgc
    50521 cagaaacttc aagttcctct gcattgtttc caagacgatc aaaggtctta tgtgtatcgt
    50581 aattttccaa atagacagca agctgaacct gtgaagaatc cttgacagca ctcgcaccgt
    50641 agagactcat aacatcgata ataccaaccc cacgaatttc aatcaagtgt ttcaaaattt
    50701 cagctggttc accccagaga gtaatctcat ccttggcaaa gatatcgaca cggtcatcgg
    50761 ctaccaaacg gtgaccacgt ttgacaagct caagacctgt ctcgctctta ccaattccac
    50821 tatctccctg aatcaagacg cccatcccat aaatatccat caagacaccg tgcacactgg
    50881 tacgttctgc caaacgagaa tccagatagc tagataactc tccagataaa cgactggtag
    50941 ctgcacggct ggttaaaata gcaatcttac attctctagc agcctttaac atctcctctg
    51001 gaaccaccaa accacgagca acaatgactg ctggtgtctc aggtagaaac atttttttca
    51061 aaacttcata acggctgttg gaaggcatgc tgatcagata agaccactcc ttcatcccca
    51121 aaagttgaat ccgctctggt gtatagtagt caaaatagcc tgtcatttca agaccaggtc
    51181 gcgtaatatc cgctgtattg atttcctttt caagcaactc tggttcacca tagacaatgt
    51241 ctagtctaag cttttcaatc acttctttta ctaaaaccga catcatttcc tccttcaaat
    51301 gagttcttct ctctattata tcaaattgta ggaggaagtt tcagattttt gcaggctttg
    51361 gagtatttat ttaaaagaaa aaggactaga tttctctagc ctttcatttc aattagaatt
    51421 ttttacgttt acgagctact tctgatttac gtttacgttt tacagaaggt ttttcataga
    51481 attcacgttt gcgtgtttct tgaagagtac cagctttagt aaccgcacgt ttgaaacggc
    51541 gaagtgcgtc gtcaagagat tcattcttac gtactactgt tttagacatt tttttcactc
    51601 ccttcaagtt caatatctat ttcattctac acgtaaaagg aataattgtc aagcaaaaat
    51661 gcggtttaat tttgattttt tcttccattt atacaagagt tgaaagcgtt caatagaaca
    51721 ttgctttttt atttttcgag taagctaagc gcttcagcat ctgcgatgat ggttacatca
    51781 gggtgatttt gaaggctact tgcaggtagg ttctcagtca ctgggccaga tactgttccg
    51841 gcaatggctt ctgctttcga ctcaccgtaa gcaaaaagaa taatagactt ggcatccaaa
    51901 atgtttttaa tccccattga aatagcttgg gttgggacgt cttcaatctt ggcaaagaag
    51961 cgtgcattgg cttcgatagt agactggtca agttctacta gatgcgtttg actgtcaaat
    52021 ggagtaccag gctcattaaa gccgatatgc ccattgcgac cgattcccaa gatttggagg
    52081 tcaactggat ggtcagccaa aatttggttg tagcgttcaa cttcagcttc agcattgtcc
    52141 ttaacaccac gaggcaagaa actttcttta aatggttttt ggttgaacaa gttttcttgc
    52201 atgaagtaac gataagattg tggattgtcc ccatcaaggc ccacatactc atcaaggttg
    52261 acactggtta gatttgaaaa atcaaggtca ctctcaacaa tttccttgta aaattcaagt
    52321 gggctacttc ctgtcgcaag tcctagagtt tgagctccat tagccaattt ttccttcaaa
    52381 atctcaaaag caacttttcc accttgaact tggttttcaa ctttaataac tttcatcttt
    52441 tcatcctcca tttctgtcta tatttattat atggtataga ccaatttttg tcaagtgaaa
    52501 acgatttaat ttctaaaaaa agagcgtcca aacttgaaac gtgttataat ggataggatt
    52561 agaacttaga aagaatgaac aaatatatga atacagctga ttttgatttc cacttgccag
    52621 aggaattgat tgcccaaacg ccccttgaaa aacgtgatgc ctccaaactc ctcatcgtca
    52681 accgtgagac aggagaaatg caagataaac acttctactc tattattgat atgctggaac
    52741 ctggtgatgc ccttgtcatg aacgacaccc gagttctccc tgcccgcctc tatggtcaaa
    52801 aagtggagac aggaggtcat gtggaacttc tcctccttaa gaacactagt ggagacgagt
    52861 gggaagttct ggctaaacct gccaaacgcc tcaaggtcgg tactcgtatc agctttggtg
    52921 atggccgcct cagcgctgtc gttacagaag aattgaccca cgggggacgc attgtccgct
    52981 ttgaatacca aggaattttc ctagaagtct tggaaagtct gggagaaatg cctctgccac
    53041 cttatatcca cgaaaaatta gatgaccgtg aacgttatca aaccgtctac gccaaggaaa
    53101 gcggctctgc tgcagcaccg actgctggtc ttcacttcac caaagaactg ctggcagaaa
    53161 tccaagctaa gggtgttcat ctagtctatc tgactctcca tgtcggactc ggaaccttta
    53221 gacctgtttc tgtggataat ctggacgaac acgaaatgca ctcagagttc tatcaacttt
    53281 ctgaggaagc tgctgccacc cttcgctctg tcaaagaaaa tggtggtcgc gtcatcgctg
    53341 tcggaaccac ttctatccgc accttggaaa ctattggttc caagtttgat gggcaaatcc
    53401 aagcagattc tggttggacc aatatcttta tcaaacctgg gtatgagtgg aaggtcgtgg
    53461 atgccttctc aaccaacttc catctgccaa aatcaactct ggtcatgttg gtttctgcct
    53521 ttgcaggccg tgaattagtc ttagatgcct accaccatgc catccaagaa cactaccgct
    53581 tcttcagttt tggtgacgcc atgtttattt attgagaaag aatttctcta attcttctaa
    53641 taccaataaa tcgctaagat attatttcaa agaacatcta caattgaaac tctagctagc
    53701 tgtagaagac gcctagtaca ttgaaattaa aatgcttccc cctagcttcg aaaatattgc
    53761 catagattgc gttgactctc caaattgatt catctatatt ttatttcagc ttcctatatt
    53821 ttcttcgctg tttgtaaatc aaaatgcaag acacatgagt agcaccatat ttgttactct
    53881 tatctgtcct ctcaagagac tattatgagt tatttcagaa tcattcacta ctttgaccct
    53941 gactctcctt agtctcaaaa tcaaagactt atactcttca aaaatctctt caaaccgcgt
    54001 caacgtcacc ttggattata tatgtgactg acttcgtcag ttctatctac aacctcaaag
    54061 cagtactttg agcaacctgc gactagtttt ctagtttgct ctttgatttt cattgagtat
    54121 taaacaaaaa gtgaacaaat ctgaattcta atgtacagaa gactaggctt gttcactttt
    54181 ttatagtcgc tataagatga ccttatctat agctttttat atataattat atattcagac
    54241 atactattat caattttgtc gcagggagga atctgttaac gcacccattc accattatca
    54301 ttgactctat agccatctat acttgtattg accgctaact cacccgatgt atttacataa
    54361 taccatttac caccaacttg gaaccattga ttgactttca tagaaccgtt gctgttgagg
    54421 tagtaccatg aaccattaac ttgtacccaa cctgttgcca tggaaccatc agtattataa
    54481 aaataccaca taccattttc ttgtttccag cctgttgttg gagcaactgc tttagctggt
    54541 tctactgcta catctgttcc ttggttagat gtaacagata caggatacga aggaatagat
    54601 gattgctcag gaacaacaac tttttcaggt tctctcgtcc ctctccttat acgtcttttt
    54661 accatctctt tagtaatttg acgagaagta gtttcttcaa ttgttccatc acgttcatct
    54721 acagtataga ttgtagtaag agtaatttac caatttctcc tacttcttct acttcttgac
    54781 ttttatcaag agttgggcca tcgagatatt ctgtttcgat tgaaatttct tggacaagaa
    54841 cttggggctt ggttcctttt ttaacaactc ttgtttgaga gtcttctttt tgacttaaag
    54901 tactctcagt tacttgtcca ctctttccat ctacatcata agttatcgtt gtaactattt
    54961 tcccattctt tcctagagta atctcttgct cctgtcctgc agaaaggtca ttgtctgctt
    55021 catatttagt agcaaatgga acaaaaactt cttcaacctt gcttttagct ggaactttga
    55081 taactgtatc cgtggcttct tttctatcaa cagtaacctg ttcggtaaca tgaccagtct
    55141 ctggattaac atcgtaggtc cttgtcgtag ttacatagcc atcctctcca tcaattgtaa
    55201 caggattttc actacggtct tttgtttcat ctttttcata acgaattcgc gtacttgaaa
    55261 ttttcttggt tactacctta ggtttagtcg ctacttttac aataatatcc ccattgtcag
    55321 cgtcatcata ctctattccc tcttctttat ctctagtatc atctctgaca tattgaatcc
    55381 catcagcagc atgaacaaaa cttgtattca gattcctcct aaaaataaag ttagcccgat
    55441 taccgcagaa ccaaaaatct ttccgagttt acgtattgca tagcgcttat tagtattaga
    55501 ttttgccatt acatcctact tctagtatag catcttttct atcaaacgtt aaacaatata
    55561 ctttatatat aaaatagact tagaatgata tattgattat tgaactaaca ctttaactat
    55621 atcgtaatca atctcatata taaaggattg cagacatctt atctaaatac atgctaatat
    55681 atttagatac aaacattcca acttgataat tttcactcat ctttcatcat tccttataca
    55741 actatgcagt ataaatagaa tagttttctc atcagaatga gactatttta atattagata
    55801 atttgataga aaaaacatga ataaaattgg ttgaatttaa ttccctaact cgatagagga
    55861 ttctatttta aatttaacaa cagctaggat tacactataa aaagtacatt accacctgtt
    55921 cggctggaga atctagtcga ttaggtccct cttagttaca agcttaaagc gattttttaa
    55981 ctaatactaa accagattaa agaaggaact agaacatctg tcttgtacta atcaatatgc
    56041 tattttaaag tttcaaataa acttggaatg ctaattatta tatttacaat aaatagttga
    56101 cttcgataga aacagaaaat agaattcaac attcttccct acttatacca taataaataa
    56161 gatccgcaag atagcctttt ctctctacac cattaacaat ggtttgtaga taggacattc
    56221 cagccttttc catgacacga cctgaagctg ggttgagact ggcataacgt gctctgacct
    56281 tttgaaaacc tgcttgagta aaacaaaagt ccaagatagc tttcaaggcc tctgtcatca
    56341 taccatgtcc ccagtaagcc ttgcctagca catagccgat ttcacagctt aaatcagcct
    56401 cgtctatctt aacaatgctg atatctccta tcacttgctc tgggttttct tttagacaaa
    56461 tggcccattt ataatagttg agattagtat aggaagcaac ccaattgcga atcgagtttc
    56521 gagtgatttc gatatcagga tggggatccc aggtaacata ggtcagattc tcagcggatg
    56581 aagcccaatt ttgaaacata gcttctgcat cactctccac aaatcttctt aaaatcaaac
    56641 gttctgtctg taatatttgc gtaccaatag atttcatgat gctacctcac ttccttattt
    56701 ctatgctcgt agtaaaaagg ctcaactcag taacagctag aaaacgagtt tgtcttctaa
    56761 tttcttgacg caatcgctgc ctggtttgaa atgcgatcta gcaagctttt tcaaacctag
    56821 tcatcgttgc aggggtaaga cgatgaaatc gaactcttcg agttaccgaa tctgcctcat
    56881 tttcttattt ctaaactcgg ggttcaagat cccccagacc ttctctcact ttcttatttt
    56941 aagatgagag gctgaaaacc tccagtggag gtttttcttg ctttttaatt tcagggcaag
    57001 aagctaaaaa ggtcccccgg acctttttac tcccaaaagt catcaaatac agtgatgggt
    57061 aagtggcgtt tgtgttggcc tttgtgccac cagttttcaa tggtcgcttg agcttctggg
    57121 ctgattgttt tgccttctag gtagtcgtca atctctgcgt aggtgactcc aagtgcgact
    57181 tcgtcagcta ggcctggttt atcttcttct aggtctgccg ttgggatttt ttcataaagg
    57241 gctggctctg cgccaagttt ctgcaagagc tgttttcctt ggcgtttatt gaggcggtaa
    57301 agagggagaa tatccgcacc gccgtcacca aacttggtaa agaaacctgt gatattttcc
    57361 gcggcgtggt ctgttccaat gaccgctccg ctatgggaac cagcaagggc atactgagca
    57421 atcatacggc aacgtgcctt gatattcccc ttgttgaagt ctgaaacagg actacctgtc
    57481 gcttcaactg cagctgtcat ggcatcagct gattccttga tattcacaac caagctgaca
    57541 tctggctgga tgaaggctag agctttttga gcatctgctt catcagcttg cactccgtat
    57601 ggcaggcgga cagcgataaa tttgtagcta tcgtctcccg tttcagctcg cagttcttcc
    57661 atagctaatt gcgccaaacg ccctgccaag gttgagtctt gtcccccaga aatccctagt
    57721 acaaaggttt ttaggaaggg atgttttttc agatatcttt ttaagaaatc aatagaacga
    57781 cggatttctt cctgggcatc aatcactggt ttgacaccca gctcttggat aatcgtttct
    57841 tgcaaactca ttcttcttct ccttcaccaa gggcttcctt gcgcatctta tcaatcaagt
    57901 ccatcttatc ttgccataca tcacgcgcca aatccactgg atagtgctgc ggattgagca
    57961 cacgcttata ctcatcccac aacttgtcaa attctttacg ggcataatcc tgaatgtcag
    58021 tcaaactagg caagttgtaa actaatattc cttctttgaa gatatccacc aagagaggaa
    58081 cggcatcaaa attacgaacc gtcttcttga tgtatgtata ggtcggatgg aacatcttga
    58141 tttctgtcat gtcgctaata tccacaccat cataagtgat atagtcgcct tctgacttgc
    58201 ctttttcacg actggtaatg cgccacacct gcttcttacc tggcgtagaa actttttcag
    58261 cattattaga cagcttaatc gtattgcgca tctgaccagt ttcatcttcg attgcaacaa
    58321 tcttgtaaac tgcaccaaga gctggctggt cataggctgt aatcagcttg gtacccacgc
    58381 cccagacatc aatcttggcc ttttgcatct tgagattgag gatagtattt tcgtccaaat
    58441 cattagaagc ataaatctta gcctctgtaa atccagcctc gtccagttgc tgacggactt
    58501 tcttagaaat gtaggcaata tccccagagt caatccgcac acccataaag ttaatctgat
    58561 cacccagctc acgcgccacc tgaatggcag ctggtacacc gatgcgaagg gtgtcatagg
    58621 tatccacaag aaagacacaa tttttgtggg tcgcagcgta agccttgaaa gcttcatagt
    58681 cattgccata aacctgtacc aaggcatggg catgggttcc caaaacagga atgtcaaaga
    58741 gcttacccgc acgcacgttg ctagttccat tggcgccacc aatcacagct gcgcgtgttc
    58801 cccagatggc cgcatccatt tcttgagccc gacgtgtccc aaactccatc aagggttcat
    58861 cttcgataac cgaacgaata cgagctgcct tcgtcgccac caaggtctgg tagttgacga
    58921 tgttcaaaag agccgtttcg accaactgac attgggctag aggtccttcc acctgcacaa
    58981 tcggttcatt agcaaaaacc aaatcccctt cttgggcaga acgaacggtc aactccaact
    59041 tgaaattgcg aaggtaatcc aagaacgccc catgataacc aagcgactcc aaataggcta
    59101 tatcactatc tgaaaaacgc aagtcttcaa gatagttcac aattctttcc aaacctgcaa
    59161 aaaccgcata gccgttctta aaaggctgtt ggcggaaata cacctcaaag accgccttct
    59221 tattgtgaat cccttggtca aagtaaacct gcatcatgtt gatctggtac aagtccgtgt
    59281 gcaatgtcaa actatcatct ggatacatac ttttcctact tccttagcta gaaacccatg
    59341 aaaattttca agaactttca tgtattccaa taaattagta ctattatatc acattttagc
    59401 tggattgaga aaagagtaac aagctattct ccactctcca attcatccat atcttgttca
    59461 aattttttct gagcccattc gccatagctc ttaagaccaa gattgccaat aaagatccac
    59521 ggaaggtaaa tgatataagt aatgacccaa gcagacaggt atttaaaatt caaaggattg
    59581 tgctgataaa tttctatgtt gaattgataa ttctgcaaca tcaaaagagc cgtaatagcc
    59641 aaggttagga aaaaacaacc caaaatcgta aaatgaaaac gactatagta ggtcactccc
    59701 agataacggg cacgattgaa aaagtaaaat gtccctatga tgataacgat tagcagcata
    59761 ttagaattaa aaaggcttgg tgctaatact gaaatgatat aagataggag cgacaaagcg
    59821 atgcagatat agaaactttc agagcccgct ttattgaaca gttgttcttc tctttcgtct
    59881 agtaattgat aataataaaa tctatttttc atcttcttcc tcccaaaata gttggtctag
    59941 ggttttccct aaacatctgc aaatggactg gcagagcgag agactgggat tgtatttccc
    60001 cgcttctatc aaaccaatag tctggcgcgt caccccgaca gcctctgcca gttgaccttg
    60061 tgttaaatca cgctctaccc gagctaattt taattttaaa tttttagcca ccttcgtcct
    60121 ccttatagtt ttaatactca tctactctta aaaaatccaa aaccaacaca agctatcagc
    60181 tatttattat aaccccatta atttgcactc cagtattatc ttcagccgaa aatcagtatt
    60241 ttaggttgtt tgaaataaac ttcctagttt actcttttat ttttatttag tattagcttt
    60301 agtaggatct tttaaacgag tttttattgc ttatatttct tgtttagttt agttggtttc
    60361 atatcactat tatataatgc ttttggaaat gagcctagta taagtcaaaa acgtgttgaa
    60421 tagtgaaagc aggagcatac caagatgact gattttttta ttgtatttta ggtatgcaaa
    60481 ataatactaa atgaaactaa aatgaatact tcttgctttt cttgagagtg aaaaagtaca
    60541 ataaaatgat tgtagtgatt accacaagat actgactaat agacatcgta tttgaagcca
    60601 caaatacagg taaagaataa aaaggaagaa gttcaattgc tttgataaac aaatcattac
    60661 tagtattcat catcatcgta tttaatatat tagggataaa gagtagtaaa gctactaaaa
    60721 taccaaatac caagccactt ttcaatttgt ataaataaaa aatgtaagat aatagaaaat
    60781 aaaacaggac taacaaaatt gtattgacta caatagctac tataaaatct aatcctaaat
    60841 cacctggaat acccaattta cttactatga ctagtaacac aatgccattc aaagcataaa
    60901 taatggaaac tgagatggca tatagaaaat tagacaagac gtaaatcatc cgattcttct
    60961 gtttatttaa tttcatgatt ataaccttcc tttattttga acgatttagg taaatatctt
    61021 taagcgtctc ttttttagtt tcaaaatcaa ctactttaat agagttttcg ttaaaaaatt
    61081 taaaaagctc actattttga atattcccag acatagtaat tctcaatccc tcttcctgaa
    61141 caatatcccc aaattcttgt ttggtaatga aaatgtctct atctgtagct gatgaaaaag
    61201 ctatctcaaa caagaaatta tgactatctt ttcctacttt ttgaaatgtc aaaagcccgc
    61261 tctccaagaa aagaaccctc tcacaaattt cttcaatgtc ttctaattta tgactcgata
    61321 ttaaaattcc cacgttttca tttaaagcta atttttttta gaaccgctaa aactatttgt
    61381 gatgattcaa tatctaaacc attagtcggt tcatctaaaa tcaatatatc aggttccgta
    61441 acgagagtta gaagcaaagc taatttttgt tttgtaccca aagaataggt ctttactttt
    61501 ttattaatag actgagtcaa atctaactct tggatcaaac ttctaaatct ttcttgattg
    61561 tagtcaacac catataaatt tgacaaatat tttaaattct ctaaacctgt tttagataaa
    61621 aataattttg gttcttcgat taaataccca acattatcac tgtttataat attacctgaa
    61681 gtcggttgat tattttgaac aagaattttc atcaacgtac tcttaccaac tccatttctc
    61741 cctactagac caacaatttc acccttgtta agtgcaaaat ttatatcttt gagaatgatt
    61801 gaatgaccat aatgcttact tacatttata acttacattt tttattcctc cattaatatt
    61861 catggtttgc tctttgattc ttattgagtt taaaaagttg cgcctctttt taacaatatt
    61921 atatcatata tctaacttaa tgcaatatat aaatgtcatt ttgtaaaatt ttattaacaa
    61981 aaaactctct acaacaaaat aatagagagt tttctgctta ttaatttttt tcaaaatatc
    62041 taagacatcg cttctttgtt taatttgata ggctttaata cctaagctcc gactttatca
    62101 cttaaaaaat aaaaaaggac agctaatctc ttgcgcatca agggatttcg ccattcttta
    62161 atctcgttta agtgttgtat atggagcttt gcataatttt ttaaaactaa acaactacat
    62221 taagcacgaa ctgtgacgct ggttccatct tccttataaa gattgataag cccctcttta
    62281 agagctcgaa ccatgtctcc agcttgaaca agttgtggga ctttaatagt caatagttcc
    62341 attggatttg gagcgcggtc gattttattg cctttggcat catgcaaatc ttcaatatag
    62401 gtttcaaaat gacggaaacc tggaccataa aactcaactt ggtccccttc gttaatgacg
    62461 ttccgttgac gaatggttgc tgtttgtgtc gcatcatcat aagaaaccac ttcagcgaca
    62521 aacttgtact cagggatttt acgacgagca ccaaacaact gctcattttc agatggtgta
    62581 ccatagtaaa atcctgtagc cagttcacgt tgggcaacct tccacatctc gtccaccaag
    62641 tcttgtttga tagcttcaaa cttttcagga ctttcaagat aggcatccac agccgccttg
    62701 tagcagttgg ttactgttga tacatagtga atagactcca tacgtccttc gatttttaga
    62761 ctgtccacac cattttcaat catatctgag atatggtcaa tcatagacat atcaacggct
    62821 gacattgaaa attcttctgg aatctcaccc tgcaaactct tacgttcttt cccaaatggc
    62881 atatcgtaaa ggtcgtactt ccaacggcat gactgagaac atccaccacg gttggcatca
    62941 cgcatactct agacggattg ttttgacaat tctaaccttt tagactttgc ataataactg
    63001 ttaaacagtc gaaaattacc ccagttttaa caagtagtca aaataccaga taaagtaaaa
    63061 aggggctagg aaaaaagtct ttaaaatctt aaaaacgcat agtatcaggt attgaacaat
    63121 cttgatatta tgcgttttat tgtgggaaga tttacttcat tttctcttgg aattgagttt
    63181 tctcctactt caaaactaga tgatttgcta tttaaaatag cgttccttat gattttggca
    63241 acctggatta aagcgagaaa aacaaaagag gcaacttaag ctttctttat attgcttata
    63301 tgttaatagt tttagacaaa caccacataa aataggctta tcctgtatca aagataaggg
    63361 ataaggctca aaagggtgat tttctaatga atcatgacac cgataacaag cataatactt
    63421 tttacaatca tagcattgta aagcaataat atccagcttg ctatggtaat gaatgcatct
    63481 tgtttgctta tccactaaga aaccctgtgc ctctatcatt tccttttcct ttcttaagct
    63541 cgaactgtga cgctggttcc atcttcctta taaaaattga tgagtccttc ttttaatgca
    63601 cgaaccatgt ctcctgattg aacgggttgt gggactttaa tagtcaatag ttccattgga
    63661 tttggagcgc ggtcgatttt atttcctttg gcatcatgca aatcttcaat ataggtttca
    63721 aaatgacgga aacctggacc ataaaactca acttggtccc cttcgttaat gacgtttcgt
    63781 tgacgaatgg ttgctgtttg taccgcatca tcataagaaa ccacttcagc gacaaacttg
    63841 tactcaggaa ttttacggcg agcaccaaac aactgctcat tttcagatgg tataccgtag
    63901 tagaaacctg ttgccaattc acgttgggca accttccaca tctcgtccac caagtcttgt
    63961 ttgatagctt caaacttttc aggactttca agataggcat ccacagccgc cttgtagcag
    64021 ttggttactg ttgatacgta gtgaatagac ttcatacgtc cttcgatttt tagactgtcc
    64081 acaccatttt caatcatatc tggaatgtgg tcaatcatag acatgtcaac ggctgacatt
    64141 gaaaattctt ctggaatctc accctgcaaa ctcttacgtt ctttcccaaa tggcatatcg
    64201 taaaggtcgt atttccaacg gcatgactga gaacatccac cacggttggc atcacgcata
    64261 ctcatgtggt ttgaaagagt acaacgtcca gagtatgaaa tacacatagc tccatggaca
    64321 aaggcttcaa tttcaacatc tgtacgtttg cggatctcag ctaattcttc cattgaaacc
    64381 tcacgcgcta aaacgacacg agtcaagcct agctctttcc agaactcaag ggtttcatag
    64441 ttagtggcac tggcttgggt agaaaggtgg atttcaaggc ctggtgcttc agtcgctgca
    64501 atcataatca aggctgggtc agatacgata actgctgcaa tcccgatatc acgcagttta
    64561 cggaaccact caccagcacc agcttcattt ccttcgtgca taaccatatt agccgctaca
    64621 tagaccttgg caccatactt ggccgcaaac tgcacgcctt cttccatctg ttcgaaagta
    64681 aagtttcccg cacggctacg aagaccatag gcctgaccac cgataaagac agcatctgct
    64741 ccatactgaa cagctacctt tagcttctct aaagtccctg caggtgataa aacctcagga
    64801 cgttttaatg tttttgtcat gatttctcct atttgcaata taaaagtttg acatttttcc
    64861 ttctcatttt atagtaaata aaggataaaa tcaagcctag acggattgtt ttgacaattc
    64921 taatctttta gactttgcat aataactgtt aaacagtcga aaattacccc agttttaaca
    64981 agtagtcaaa aagtctaaaa aagtaaaaac cagtatccca agatactgac tcgtaaaaat
    65041 acataaatta gtccttagat gactactccc actctgttgc tcctataatg gaaaaggatt
    65101 gatacagtct agaatatcgc ttttttattt attattctga tataaaactg ttagaattga
    65161 ttttttgttt tatacccaaa tatgaataga gacgtagcta ataagttgaa taacatattt
    65221 ggaaaaatga gaaatagcaa tattactaga acttttagaa acaatcaata tttaaaaaga
    65281 aaaaagctca aagaatttat taaaccatgt tataatagat atagctataa ttttatttat
    65341 aacaagagga tagaaatgac cgaattagaa agaaaaaatc gaaaaattag ctaagaaata
    65401 ttctgataac ttaaacatca aagttcaaga gagagttcgt gaaatggcaa atgataataa
    65461 gagccattat ttgatataca gagttttagg tatttcattt gaagaaggag aaaatatcga
    65521 tttgtatcaa aataaaggtc gttttttata caaatatgct ggttcatttt tagaagaagc
    65581 tgcagtacta tcctttaacg aaaaatttgg tacagaaaat acttaaaaag ttaacattcc
    65641 taattctgaa aatacaaaac ctaagacttt tgaaattgat tgtttagtcg gagaaaaaca
    65701 cgcatacgaa ataaaatggt gggatgcaac tacagatgga gaccatataa ctaaagaaca
    65761 cactagaata aaagttattc ataacaaagg atatatacca attcggttaa tgttctacta
    65821 tccaaataga actcaagcta taaaaattca gcaaacttta gaaacattgt ataacggtat
    65881 tggagggaaa tattattatg gagattctgc ctgggaacat ttaagagcag tgaccggtat
    65941 tgatttactt agtattctaa cagatattgc aaataaaaaa acaggggtaa aatcaaaatg
    66001 acagtattaa aaggagataa cttagaaata ttaaaaacta ttgaatcctc aagtattgat
    66061 ttaatctata tggaccctcc tttctttaca cagaaaaccc aaaaattatc taataacaaa
    66121 aatattatgt attcattcga agatacgtgg acttcgattg aggattacaa agaatttttg
    66181 tctgtaagat tagaagaatg caaaagagtg ctaaaaaata gtggcagtat tttcgttcat
    66241 tgtgataaaa ttgcaaatca tcatattaga ttaattttag ataatatctt tggagcagat
    66301 atgtttcaaa gcgaaattat atggaactat aaacggtggt ctaattcaaa aaagggatta
    66361 ttgaacaatc atcaaaacat ttacttttat tcaaagtcaa aagattttaa atttaataca
    66421 atttttacag agtattcttc tactacaaat atcgaccaaa tactagtgga acgaaaacga
    66481 gatggaaact ctaaaactat atataaggtt gataataatg gtaactatat tctagcaaaa
    66541 gagaaaaatg gagttcccct ttcagatgtt tggaatatac catttcttaa tccaaaagct
    66601 aaagaaagag taggttatcc tacacaaaaa cctattctgt tattagaaca aattataaag
    66661 attgctactg ataaaaatga tatagtttta gacccgttct gtggaagtgg aactacttta
    66721 gtagcctcca agattttgaa tagaaattat atggggattg atttatctga ggaagctatc
    66781 aatataactc agcaacgtct ggaaaatgtt ataaaaacaa gttcaaattt attgaataaa
    66841 ggaatcgaag catatagaac caaaactgag gaagaggaaa acattcttaa attattacag
    66901 gcaaaaattg ttcaaagaaa taaaggaatt gatggttttt tacctaaaca ttttcaaaaa
    66961 aaaccgatac ctataaaaat tcaaaaaaat aatgaatgtc tgaatgagag tatctcttta
    67021 ttacagaatg ctataaactc caaaaaactt gattttggag tagttataaa aactcattca
    67081 gataatttat tatttgattt tgatacgatt cctgaaaata taatagtagt tgaccatttt
    67141 gaacttacaa tcgaaaaatg gttaagtaaa agtcaacagt tactatagtt tgcaaattat
    67201 ttacagaaag aacaaaaaat gctctgaaac actgatttca aggcattttt tgttagttta
    67261 aaattactcc cattcttctt ttccaaacgt acaatatatc caaaaccatt caaaatacta
    67321 gattctattt tttataatat cactaaatcc acctaattat aggacgtttt cagattttta
    67381 gtcccgtccc agtcccagta ccggagaaat attgttttaa tataatatct ctttttgtct
    67441 tctaagctct taaaagcaaa agaacaagta aagagtcaag acaaggataa aaagtccata
    67501 ttagggcaaa taaaaagctt taagacagat gacaaatcta agtcaaataa gaaagaccat
    67561 agcaaaggtg cagagagata aatattggcg gtcttcggac tgcctttatt tttttatcca
    67621 tttttcaaat caaatttatt cagactatat atgcacatat acacttaaat tcatataaaa
    67681 acatggcttg taaaaaatta ctttaatcac aataatcgca tttaaaattg tgatgtttgc
    67741 aagctaaatt acggacttca cttggaagtt ttcccttgta tcttttataa tagatagaaa
    67801 atttgctggc agatgaatat ccaacagatt ctgctatctc ttttataggt agttcagtgt
    67861 ttaaaagaag agtttcagct acattcattc tttttctttg agtgtactct gtaatgcttt
    67921 gacaatattt ttccttaaat aaatttttta atttagtacc actcatttta gatatttttt
    67981 caagcgtgcc ttgatttaca ttcgttgcaa aatgatcatc taagaatctt gctacatctt
    68041 caagtgcttt atcatcatca atttcaattt tatatttttt tctatttaag tatgtgtcaa
    68101 ttactatact tatccattca tttgcctttg ctttaaagaa aaaatcagcg gcaggagcgt
    68161 ccatcttaca atttaatatt tccattgcca ctctttctaa ggcctttgta agtattattt
    68221 gattcggttg aagcaaggtt gaataaaaag attctggatt aatgttaata gatgctaaat
    68281 gtttttctat tagctctttt ttaaaaccaa tggaaacagc aagataacaa caattctcgt
    68341 gtaataaaaa aacaaaatca tcttttatat tatcaaaatc aaaagtacat aaagagtttg
    68401 cggtaatagt ttgatacgga ttaaactttt ctccgtttgc actgacaatg taacttgaat
    68461 aaattgaaac atagtctgac atactataag tgctattttg aactacttcc tctttgatat
    68521 aaaaatcatg tatatcgata atgaagctgc ctccttcata aaaccaatat aggccttctg
    68581 cataagttga attctctttt ttccaacaaa atgtatgacc tgcacttgaa tacttctcat
    68641 tgtttttaca ttcatctact ttcatataat cttttacaaa atcataatat gacataacac
    68701 actatccctt ttagacaata ttccaattag ccttattaat tcaaaactat tgtattagta
    68761 attataacag atgtataata gaaaagcaat gatagatatt atcaattaag cgaatttata
    68821 tctaaaaggg atattaaaga aaggagatat gcttatgaag atttacaaaa aactatttgc
    68881 ttatgtccaa gataagaaat atcttggggt tttggccata attttttctg ctatatctgc
    68941 tctacttaca gtatatggat attatttaat ctacaaattt ctagataagt taataattaa
    69001 ttcaaactta tccggtgcag agagtatagc attaaaatct gttattacac taacaagtgg
    69061 agcgatattt tattttgtct caggaatgtt ttcacatatc ttgggattta ggcttgaaac
    69121 aaatttaaga aaaaggggaa tcgatggtct ggaaaaagca agttttaggt tctttgactt
    69181 aaatccatct ggtcaaataa gaaagatcat agatgataat gcagcacaaa ctcatcaggt
    69241 ggtagcacac atgattcccg atagttctca ggcaataatc acacccgtac ttgtacttgc
    69301 acttggcttt atagtaagta taagggttgg cataattttg cttgctctta ctataattgg
    69361 tggcttaatt ttaggggcaa tgatgggcga gcaagaattt atgaagatat accaagaatc
    69421 cctatctaaa ctaagtgctg aaactgttga gtacgtgaga ggaatgcaag ttgtaaaaat
    69481 atttaaagca aatgtagagt cttttaaaag cttttataag gcgataaaag attactcaaa
    69541 gtatgcttat gattattccc tatcttgtaa aaggccttat gttttgtatc aatggttatt
    69601 ttttggactg attgcaattt taattattcc tatagtttat tttatgacta gcttagctag
    69661 cgcaaaggtg attttacttg agcttatcat gattttattt ttatcaggag ttctctttgt
    69721 ttcattcatg agaatgatgt ggtactccat gtatatttct caaggaaatt atgcagtaga
    69781 tactttagag gcgctttacg aagatatgca aaaagacaaa ttagtgcatg gtaatgtcaa
    69841 taattttaaa aactataata tagaatttga gaatgttagc tttgcttata atgataaagc
    69901 tgtcattgaa aatttatcct ttaatttaga agaaggaaag tcctacgcac ttgtcggttc
    69961 atctggatca ggcaaatcaa cagtagcaaa acttatatca ggtttttaca atgttaataa
    70021 aggaagcata aagataggcg ggatagcaat aagtgaatat tctgacgaag ccttaattaa
    70081 agccatttcc tttgtttttc aagattcaaa attattcaag aagagcattt atgataatgt
    70141 agctttagct aataaagatg cgacgaaaga tgacgttatg agagccttaa aattagcagg
    70201 atgcgattta atattagaca aattcccaga aagagaaaat acaatcatag gctcaaaagg
    70261 tgtttattta tccggtggag aaaaacaaag aattgcaatt gctagagcaa ttttaaagga
    70321 ttccaaaatt attattatgg atgaagcatc agcatctatt gacccagata acgagtttga
    70381 attgcaaaaa gcttttaaaa atcttatgaa ggataaaaca gttatcatga ttgcacacag
    70441 gctatctaca attaaagacc ttgatgaaat tattgtcatg gatagtggaa aaattataga
    70501 aagagggtct gacaaagaat taatgtcaaa agatacaagg tataagagcc tgcaagagat
    70561 gtttaacagt gcgaatgaat ggagggtttc aaatgaaaga gttttataaa aaaagatttg
    70621 ctcttacaga tggaggagca agaaatttaa gtaaagcaac actggcttca tttttcgttt
    70681 attgtataaa catgcttcct gccatattac ttatgatttt tgctcaggaa gttttggaaa
    70741 atatgggcaa aagcaatggc ttttatatag tattctcagt tttgactttg atagcaatgt
    70801 atattttgct ttctatcgaa tacgataaat tatataacac aacctatcaa gaaagtgcag
    70861 atttaagaat aaggacagcg gagaatttat caaaattacc tctatcttac ttttctaaac
    70921 atgacatttc cgacatttca caaacaatca tggctgatat tgaaggcata gagcatgcaa
    70981 tgagccactc aataccaaag gtgggcggca tggtactgtt tttcccatta atatctgtaa
    71041 tgatgctagc gggcaatgtc aagatgggtt tagctgtaat tattccatct attttaagct
    71101 ttatatttat acctttatct aaaaaatatc aggttaatgg acagaataga tattatgatg
    71161 tcttaagaaa aaactcagaa agctttcaag aaaatatcga aatgcaaatg gagattaaag
    71221 catataattt atcgaaggat attaaagatg acttatataa aaaaatggaa gatagtgaga
    71281 gagtacactt aaaggcagaa gtaactacaa ttttaacttt gtctatatct tcaatattta
    71341 gctttatatc tcttgctgtt gtgatatttg tcggcgtaaa tctaattatt aataaagaga
    71401 taaattctct ctaccttata ggatatttac tagctgctat gaagataaaa gactctttag
    71461 atgcatctaa agagggcttg atggaaatat tttatttatc gcccaaaata gaaagattaa
    71521 aagaaattca aaatcaagat ttacaagaag gcgatgacta tagcttaaaa aaatttgata
    71581 ttgatctaaa agatgttgag tttgcctaca ataaagacgc aaaagtttta aatggtgtaa
    71641 gttttaaagc taagcaggga gaggtcactg ctttggtagg tgcaagtggc tgcggtaaaa
    71701 caactatctt gaaacttata tcaagacttt atgattatga caagggacaa atcttaatcg
    71761 atggcaaaga tataaaagaa atatcaacag aatctctttt tgataaggtc tctatagttt
    71821 tccaagatgt ggttctcttt aatcaaagca ttatggaaaa tattagaatc ggaaagcaag
    71881 atgcaagtga cgaagaggtt aaaagagcag caaaacttgc aaattgcaca gattttatag
    71941 aaaaaatgga taaaggtttc gatacagtta ttggtgagaa cggagctgag ctatcaggag
    72001 gagaaagaca aagattatca atagccagag ccttcttaaa agatgcgccg atattgatct
    72061 tagatgagat aacagcaagc cttgatgtta acaacgagaa aaagattcaa gagtctttaa
    72121 ataatttagt taaagataaa actgttgtaa tcatttcaca tagaatgaaa tccatagaaa
    72181 atgcagacaa gatagtagtt cttcaaaacg gaagagtaga aagcgaaggt aagcatgaag
    72241 agcttttaca aaaatcaaaa atttacaaaa atttaataga aaagacaaaa atggcagaag
    72301 aatttattta ttaggaggac tacaatggat aataaaaaat taaaagtaaa agatttagta
    72361 agtatcggtg tttttggcgt aatttatttt gccttcatgt ttggagttgg tatgatgggc
    72421 ttgattccaa tattgttctt aatatacccg acagtattag ccatagttgc aggaactgtt
    72481 gttatgttat ttatggctaa ggttcaaaag ccatgggcac tatttatatt tggtatgata
    72541 tcaccacttg tgatgtttgc agctggtcat acctacgtag ttgtggtttt atcacttata
    72601 gtaatgataa tagcagaatt aattagaaag attggtaatt ataattcatt taaatacaat
    72661 atgctttctt atgcaatctt cagcacatgg atatgtagct ctttaatgca aatgctttta
    72721 gcaaaagaaa aatatatgga gtggtctttg atgacgatgg gaaaagatta tgttgatgta
    72781 ttagaaaagt taataactta tcctcacatg gctttagtag ccttaggtgc tttcttagga
    72841 ggaattcttg gagcatatat aggcaaggct ctattgaaaa aacactttga aaaagcaggc
    72901 attgtataat gtctactttt tcttcaaatg ctccctttaa tcccaatccg atctctaaga
    72961 tattagtcgt atttatcaca ggcttaactg ttatgcatag cataaacatc cgttttgagc
    73021 tggcaattgt ttgtcttatt ggtattttgc tttatttgaa tggatacaaa aaaacacttt
    73081 tcaaatggat tatattgtgt gggatacttt actccttgcc taattttatg gtgttatctg
    73141 aattaaaccc tatagttaag atgtttttga gtatacctat tgttattaga atgtttattt
    73201 taccatttat ggcagcaagc tttatgataa agacctcgga tgtaggcgca ataatttcat
    73261 cgatggataa gcttaagatt tcaaagaatg tatccatacc tattgcggtt atgtttagat
    73321 tcttcccatc ttttaaggag gagaagaaaa acatcaaaat ggctatgaga gtaagaggga
    73381 taagttttaa aaacccagtc aaatatcttg aatatgtttc tatgccacta ctcattatat
    73441 catctaatat atcagatgac attgcaaaag cggcagaaac aaaggcaata gaaaatccaa
    73501 ttgccaagac cagatacatt cgcgtaaaga tacagctaat tgattttgtt tatgttttag
    73561 cggttgctgg acttattgtg ggaggcttaa tatggttgaa ataaaaaatt taagtcttga
    73621 ttatggtgaa gagcatatat tagatgatat atcactatcc atagccgagg gagagtgcgt
    73681 gctatttaca ggaaaaagtg gaaatggtaa gtcatcttta ataaattcaa tcaatggact
    73741 agctgtaagg tatgataacg caaagacaaa gggcgaaata attattgatg gtaagaatat
    73801 aaaaaatttg gaactttatc aaatctcaat gcttgtttca actgtttttc aaaatcctaa
    73861 gacatatttt tttaatgtca atacgacatt agaattatta ttttatttgg aaaatatcgg
    73921 tcttgcaaga gaagagatgg acaggcgttt gaaggatatg cttaagatat tcccgataaa
    73981 aaatcttttg aacagaaata tatttaatct atccggcggt gaaaaacaaa ttctttgcat
    74041 tgcagcttct tatatagcag gtacaaagat tatagttatg gatgagcctt catcgaattt
    74101 agatattaaa agcataaatg ttttggcaaa gatgctaaag atattaaaag agaaaggcat
    74161 aagcataatt gttgcagagc atagaattta ttatttgatg gacatagttg accgtgtatt
    74221 tttaatagat aaaggaaagc ttaaaaaaac ttatactaga agtgaatttt taaagctaga
    74281 taaaaatgaa ttaaatgctt taagtttaag agataaagaa ttaagtaaat taaaagttcc
    74341 ttatttaaaa gaaggtggag agtatcagat aaaaaatctt agctacaaat ttactgatga
    74401 tgagtgttta agcttaaaag atatttcatt caagcttggg aaaatttatg gcataatagg
    74461 atccaacgga cgaggaaaat caacgctttt aagatgttta ataggtcttg agaaaaaatc
    74521 aaaagaagaa atttatttta agggagagaa gctatctaaa aaagaaagac tcaaaaactc
    74581 ttcacttgtt atgcaagatg taaatcatca attattcaca gatgaagtat tcaacgagct
    74641 tagattagga gtaaagaatt ttgatgaaga aaaggcgaaa atcattttaa aagatttagg
    74701 cctggacgaa tttattgaaa ggcatccgat gagtttatca ggagggcaaa agcaaaggct
    74761 tgcaatagca tctgttatgt gcaagaattc tccatttatc ttttttgacg aaccttcaag
    74821 tggtatggat tattccaata tgataaaaat atctgaactg attaataagt ataaaaccat
    74881 ggataaaata atttttattg tttcccatga tatagaattt ttaaatgaag tggcagatga
    74941 aatttttgaa ttgtaaaata gagtctgtta aacatgtcta tagaactagt aaattgtcta
    75001 aaaatttaaa agatactaac acatattgat atttatagaa aattaacttc aggattttta
    75061 ca
//
LOCUS       DBEJJV010000007        61916 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.007, whole genome shotgun sequence.
ACCESSION   DBEJJV010000007 DBEJJV010000000
VERSION     DBEJJV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 61916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61916
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.007"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..178
                     /locus_tag="ACL3GT_000498"
     CDS             <1..178
                     /locus_tag="ACL3GT_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGR0516209.1"
                     /translation="VEDKACNHALSKERSKVENIFVKVKTFKMFSTTYRNHRKRFGLR
                     MNLIAGIINHKLGF"
     gene            complement(943..1203)
                     /locus_tag="ACL3GT_000499"
     CDS             complement(943..1203)
                     /locus_tag="ACL3GT_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516210.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(1262..1813)
                     /locus_tag="ACL3GT_000500"
     CDS             complement(1262..1813)
                     /locus_tag="ACL3GT_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516211.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1803..2798)
                     /locus_tag="ACL3GT_000501"
     CDS             complement(1803..2798)
                     /locus_tag="ACL3GT_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516212.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHILKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(3206..3631)
                     /locus_tag="ACL3GT_000502"
     CDS             complement(3206..3631)
                     /locus_tag="ACL3GT_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516213.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3775..4119)
                     /locus_tag="ACL3GT_000503"
     CDS             complement(3775..4119)
                     /locus_tag="ACL3GT_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGR0516214.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKK"
     gene            complement(4165..4371)
                     /locus_tag="ACL3GT_000504"
     CDS             complement(4165..4371)
                     /locus_tag="ACL3GT_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516215.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(4358..4519)
                     /locus_tag="ACL3GT_000505"
     CDS             complement(4358..4519)
                     /locus_tag="ACL3GT_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0516216.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4878..5834)
                     /gene="lytA"
                     /locus_tag="ACL3GT_000506"
     CDS             complement(4878..5834)
                     /gene="lytA"
                     /locus_tag="ACL3GT_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGR0516217.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(6210..7580)
                     /locus_tag="ACL3GT_000507"
     CDS             complement(6210..7580)
                     /locus_tag="ACL3GT_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0516218.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(7887..9053)
                     /gene="recA"
                     /locus_tag="ACL3GT_000508"
     CDS             complement(7887..9053)
                     /gene="recA"
                     /locus_tag="ACL3GT_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HGR0516219.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(9108..10364)
                     /locus_tag="ACL3GT_000509"
     CDS             complement(9108..10364)
                     /locus_tag="ACL3GT_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HGR0516220.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(10449..11465)
                     /locus_tag="ACL3GT_000510"
     CDS             complement(10449..11465)
                     /locus_tag="ACL3GT_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HGR0516221.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(11473..11991)
                     /locus_tag="ACL3GT_000511"
     CDS             complement(11473..11991)
                     /locus_tag="ACL3GT_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0516222.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGELFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(11981..12424)
                     /gene="tsaE"
                     /locus_tag="ACL3GT_000512"
     CDS             complement(11981..12424)
                     /gene="tsaE"
                     /locus_tag="ACL3GT_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HGR0516223.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(12510..13130)
                     /locus_tag="ACL3GT_000513"
     CDS             complement(12510..13130)
                     /locus_tag="ACL3GT_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516224.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTVFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(13513..14376)
                     /locus_tag="ACL3GT_000514"
     CDS             complement(13513..14376)
                     /locus_tag="ACL3GT_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0516225.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            14568..14690
                     /locus_tag="ACL3GT_000515"
                     /pseudo
     CDS             14568..14690
                     /locus_tag="ACL3GT_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhrA family quorum-sensing system peptide"
     gene            14841..15065
                     /gene="pneA1"
                     /locus_tag="ACL3GT_000516"
     CDS             14841..15065
                     /gene="pneA1"
                     /locus_tag="ACL3GT_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HGR0516226.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
     gene            15072..15260
                     /gene="pneA2"
                     /locus_tag="ACL3GT_000517"
     CDS             15072..15260
                     /gene="pneA2"
                     /locus_tag="ACL3GT_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HGR0516227.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            15494..18364
                     /gene="lanM"
                     /locus_tag="ACL3GT_000518"
     CDS             15494..18364
                     /gene="lanM"
                     /locus_tag="ACL3GT_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="HGR0516228.1"
                     /translation="MSIISEKTFEEMLKLNNYNKKIFSNTVNYDYTEEQIRLYSEYAK
                     NSEWYKFAEGSFEIFRKHPQRINFKKDFSRILEPFIINLLKLINNYLENKEYEWIDKN
                     GNIFSSLVFYLEDLIYPWIVKPLVLEINSLREKGLLEGESEQQRYKYFITLFDKEENI
                     LNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEELGLRGKLNDIKFGKGD
                     THSQGKTVLILFFDDAKIVYKPKNLIINNSLNTIAEYIRKVDEKIRIRIPRTIAYSDH
                     SYEEFIDYLPLEQKKKLPEYYYNFGVLLAFIYLFNGSDIHFENLISYGDMPVIIDFET
                     MLQQPLFDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGLDVEMSALTGNFKKDAFNG
                     QVLINLNTDKVKFDIGKIDFEGGKNLPVRDGDIEFDKYIKDFKKGFRDFYLIFEELNK
                     TEEFKMLLKANLYGLKTRVLFRDTNSYASVLSFLYHPDFYEEMLDREKALENLWSNKF
                     SNQGIVASECEQMRLLDIPIFYTDTNINEIYDDFGNHFISLHQFSGYDYFMKYLPNNN
                     LENLEKQLDIIEIYFPSFDQRKKGYKLNLSNRKKLPNESLVTILHNEVENIADSLVIN
                     NIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAGILLFMYYVKLLKDKSSYTQLYNK
                     MLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYDTNTLACLNYIKSVLTELEKTDFA
                     SVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRLVLSLGDTLYNDVSERDNSNFGYS
                     FGHGLSGVIFTLKNIYKVTRLKKYKELILQLVPREKIKIHSLKWCSGEFGTLVNHPQS
                     VPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDTSMELESLLCSVVMNKSKEGEYRIV
                     QTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIVIPSLLEI"
     gene            18714..19418
                     /locus_tag="ACL3GT_000519"
     CDS             18714..19418
                     /locus_tag="ACL3GT_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HGR0516229.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            19399..20328
                     /locus_tag="ACL3GT_000520"
     CDS             19399..20328
                     /locus_tag="ACL3GT_000520"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HGR0516230.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLSLEEVVFTLSNYIYSK
                     NNKYLEKIKYLKKLVDFRQEEIIDFILNKEEVL"
     gene            20325..22433
                     /locus_tag="ACL3GT_000521"
     CDS             20325..22433
                     /locus_tag="ACL3GT_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGR0516231.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            22457..24196
                     /locus_tag="ACL3GT_000522"
     CDS             22457..24196
                     /locus_tag="ACL3GT_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR0516232.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGG
                     ESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIIS
                     DIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDG
                     NDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSN
                     QSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPA
                     GSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYK
                     LKDQPYNYMFVKKILEETLPVKNGIKVLNIPNVLRYDLNMLQLEYKNEQSWDSFIDNV
                     NLIELEERIQTTIGIKQINTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLF
                     ISMVNILWAKKSK"
     gene            24247..25014
                     /locus_tag="ACL3GT_000523"
     CDS             24247..25014
                     /locus_tag="ACL3GT_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HGR0516233.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            25016..25648
                     /locus_tag="ACL3GT_000524"
     CDS             25016..25648
                     /locus_tag="ACL3GT_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516234.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(26577..26990)
                     /gene="ndk"
                     /locus_tag="ACL3GT_000525"
     CDS             complement(26577..26990)
                     /gene="ndk"
                     /locus_tag="ACL3GT_000525"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HGR0516235.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(27101..30778)
                     /gene="rpoC"
                     /locus_tag="ACL3GT_000526"
     CDS             complement(27101..30778)
                     /gene="rpoC"
                     /locus_tag="ACL3GT_000526"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HGR0516236.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(30811..34422)
                     /gene="rpoB"
                     /locus_tag="ACL3GT_000527"
     CDS             complement(30811..34422)
                     /gene="rpoB"
                     /locus_tag="ACL3GT_000527"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0516237.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            34838..34908
                     /locus_tag="ACL3GT_000528"
     tRNA            34838..34908
                     /locus_tag="ACL3GT_000528"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34870..34872,aa:Cys,seq:gca)
     gene            complement(35106..36437)
                     /locus_tag="ACL3GT_000529"
     CDS             complement(35106..36437)
                     /locus_tag="ACL3GT_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HGR0516238.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRIAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(36666..37490)
                     /gene="endA"
                     /locus_tag="ACL3GT_000530"
     CDS             complement(36666..37490)
                     /gene="endA"
                     /locus_tag="ACL3GT_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HGR0516239.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(37529..37717)
                     /locus_tag="ACL3GT_000531"
     CDS             complement(37529..37717)
                     /locus_tag="ACL3GT_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HGR0516240.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(37710..38993)
                     /gene="murA"
                     /locus_tag="ACL3GT_000532"
     CDS             complement(37710..38993)
                     /gene="murA"
                     /locus_tag="ACL3GT_000532"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0516241.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(39017..39247)
                     /locus_tag="ACL3GT_000533"
     CDS             complement(39017..39247)
                     /locus_tag="ACL3GT_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HGR0516242.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDENTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(39305..40342)
                     /locus_tag="ACL3GT_000534"
     CDS             complement(39305..40342)
                     /locus_tag="ACL3GT_000534"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HGR0516243.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     INDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(40326..40814)
                     /gene="coaD"
                     /locus_tag="ACL3GT_000535"
     CDS             complement(40326..40814)
                     /gene="coaD"
                     /locus_tag="ACL3GT_000535"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HGR0516244.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGRDIACYVPESILEEIRNEK
                     KD"
     gene            complement(40804..41343)
                     /gene="rsmD"
                     /locus_tag="ACL3GT_000536"
     CDS             complement(40804..41343)
                     /gene="rsmD"
                     /locus_tag="ACL3GT_000536"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HGR0516245.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(41408..42400)
                     /gene="asnA"
                     /locus_tag="ACL3GT_000537"
     CDS             complement(41408..42400)
                     /gene="asnA"
                     /locus_tag="ACL3GT_000537"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HGR0516246.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(42513..43196)
                     /locus_tag="ACL3GT_000538"
     CDS             complement(42513..43196)
                     /locus_tag="ACL3GT_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1 family protein"
                     /protein_id="HGR0516247.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(43252..43992)
                     /locus_tag="ACL3GT_000539"
     CDS             complement(43252..43992)
                     /locus_tag="ACL3GT_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HGR0516248.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            44026..44304
                     /locus_tag="ACL3GT_000540"
     CDS             44026..44304
                     /locus_tag="ACL3GT_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HGR0516249.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            44382..45308
                     /gene="yidC"
                     /locus_tag="ACL3GT_000541"
     CDS             44382..45308
                     /gene="yidC"
                     /locus_tag="ACL3GT_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0516250.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(45383..46177)
                     /gene="pflA"
                     /locus_tag="ACL3GT_000542"
     CDS             complement(45383..46177)
                     /gene="pflA"
                     /locus_tag="ACL3GT_000542"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HGR0516251.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTRQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(46303..47553)
                     /locus_tag="ACL3GT_000543"
     CDS             complement(46303..47553)
                     /locus_tag="ACL3GT_000543"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HGR0516252.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     IWLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(47620..48447)
                     /gene="purR"
                     /locus_tag="ACL3GT_000544"
     CDS             complement(47620..48447)
                     /gene="purR"
                     /locus_tag="ACL3GT_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HGR0516253.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(48714..49655)
                     /locus_tag="ACL3GT_000545"
     CDS             complement(48714..49655)
                     /locus_tag="ACL3GT_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HGR0516254.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(49645..50901)
                     /gene="rmuC"
                     /locus_tag="ACL3GT_000546"
     CDS             complement(49645..50901)
                     /gene="rmuC"
                     /locus_tag="ACL3GT_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HGR0516255.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(50903..51565)
                     /locus_tag="ACL3GT_000547"
     CDS             complement(50903..51565)
                     /locus_tag="ACL3GT_000547"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HGR0516256.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLLLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEKNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(51528..52184)
                     /gene="rpe"
                     /locus_tag="ACL3GT_000548"
     CDS             complement(51528..52184)
                     /gene="rpe"
                     /locus_tag="ACL3GT_000548"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HGR0516257.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(52195..53073)
                     /gene="rsgA"
                     /locus_tag="ACL3GT_000549"
     CDS             complement(52195..53073)
                     /gene="rsgA"
                     /locus_tag="ACL3GT_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HGR0516258.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(53075..53947)
                     /gene="rsmA"
                     /locus_tag="ACL3GT_000550"
     CDS             complement(53075..53947)
                     /gene="rsmA"
                     /locus_tag="ACL3GT_000550"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HGR0516259.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLMPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(54198..54491)
                     /locus_tag="ACL3GT_000551"
     CDS             complement(54198..54491)
                     /locus_tag="ACL3GT_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516260.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(54484..55125)
                     /locus_tag="ACL3GT_000552"
     CDS             complement(54484..55125)
                     /locus_tag="ACL3GT_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516261.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(55127..57157)
                     /locus_tag="ACL3GT_000553"
     CDS             complement(55127..57157)
                     /locus_tag="ACL3GT_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0516262.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     LGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(57234..57530)
                     /locus_tag="ACL3GT_000554"
     CDS             complement(57234..57530)
                     /locus_tag="ACL3GT_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0516263.1"
                     /translation="MKQTVKKLALVASIAATLGGGVSVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(57850..58749)
                     /locus_tag="ACL3GT_000555"
     CDS             complement(57850..58749)
                     /locus_tag="ACL3GT_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0516264.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(58821..59381)
                     /gene="rnmV"
                     /locus_tag="ACL3GT_000556"
     CDS             complement(58821..59381)
                     /gene="rnmV"
                     /locus_tag="ACL3GT_000556"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HGR0516265.1"
                     /translation="MKEKISQVIVVEGRYDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(59381..60154)
                     /locus_tag="ACL3GT_000557"
     CDS             complement(59381..60154)
                     /locus_tag="ACL3GT_000557"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HGR0516266.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVIQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(60459..61352)
                     /locus_tag="ACL3GT_000558"
     CDS             complement(60459..61352)
                     /locus_tag="ACL3GT_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor protein"
                     /protein_id="HGR0516267.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATLEY
                     KLETIPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(61636..61770)
                     /gene="rpmH"
                     /locus_tag="ACL3GT_000559"
     CDS             complement(61636..61770)
                     /gene="rpmH"
                     /locus_tag="ACL3GT_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HGR0516268.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        18747 a        12918 c        11243 g        19008 t
ORIGIN      
        1 agttgaagat aaagcctgta accatgcgct atctaaggag agaagcaagg ttgagaacat
       61 ctttgtcaaa gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg
      121 cttcggatta cgaatgaatt tgattgctgg tattatcaat cataaactag gattctagtt
      181 ttgcaggaag tctattatat atatgcacag acatatgaaa tctttttgat acagccttct
      241 ttttacatag agagacagca gttatgatat atttatccat tcacaaaatc ttctgtacca
      301 atactacaat aattggtaca ttttgattac acaatcgttt caaaaaatat gatggaagac
      361 tgagtatttt atagtaattc ccttcctatc aactagatca accagttgag tgttgaatgt
      421 tgaaacaccc tagcctcagc aaaggactat gatcagcatt tcctagccaa taggacgctc
      481 caaatcacct attctaagtc catcactagc ttggtcagta agatacagac tgcaaggcaa
      541 gactgacgtg gttgatgaga ttttggaaga gtattacaat catagattca ccagtagact
      601 tgaccgcaga tttaactata gtagattgaa actagaatag tacacttctg cttctaaaac
      661 attgttagaa atcgatttga ctgtcctgat caatttgtcc tgttctcgtt tcattttact
      721 atactaaaaa accacctgaa acaaatcaag tgactagagg ataaaaacaa agactgggca
      781 aaaagttttg aaaagcaaaa aacgcataat atcaggtctt gaaaaacctt gctactatac
      841 gtttgattgt gggaagattg acttcatttt ctcctgaaat tgaagttttt tctagtttcc
      901 aggtatagac gaattcaata tagccatctc gctacaatta ttttaaccat cgaaaaaatt
      961 tttcagaatt tcaaaaattt cattttgatc caatgaaatg tcattatttt gaagaatagt
     1021 tgacttcaca ggctctaatt ctatcacaaa gcggtgcatg tctgctttta ccgcactact
     1081 tgatgttata gccgataact tttcatctcc tagcaaggaa gctgtcaaac gggtaaggtc
     1141 attcaaatgc tttttaatgg acttacttaa accttgagca cctgtggcag agcgctccct
     1201 catatccagc caagctttag ccttaaaaat aattaatact caatgaaaat caaagagcaa
     1261 actaggaagc tagttgcagg ctgctcaaaa cactgttttg aggttgtaga tggaagctga
     1321 cgtggtttga agagattttc gaagagtata gaccacaatt actcaatacc gaatacccct
     1381 gaatggtttc ttttacatgc accaatatat tataataatc ttcatccaat aataaggctg
     1441 ataaactagc atcttggtca aaatataagg gaatttctcg accgtccttc tttaatggat
     1501 attctggtaa gatactaaat agttcaatca tagaaggaaa ctcagaatta gttgttgtaa
     1561 atcgaaaaag ctgcgctttc tcatctttct gacttccttg atactctccc aattctaaaa
     1621 aatgattcaa ggtagtataa aattccttat tttttacttc atcaatgatg accatatcat
     1681 aatcttttgt tgtgcgactt ttaaatcctt gcgaatccaa tacgatagag gtagcagttc
     1741 ccccaatcag aacataatag ttctgaaaat ccgcaaacat ttcttgaaaa ataactttcg
     1801 tattagctgg catcatcttc tcccagatac tgtaatatca tattttctag tgcttcactc
     1861 tcttcctcta tacgtgggtc atcatcatct tttaaggtca aataaagaga aatcggatct
     1921 acaaattgtt tatcatgatt atttttaaaa tcattccaaa actcagatac aaaaggacga
     1981 tatttccata tctctagcat ctttcctttt aaaatatgct gagaaagtgg caaggataac
     2041 tgattgaatt ttctctgcca tatgacatag ctagtatttt catccgtttc agctaaaaaa
     2101 gttgaatgcg acaaagcata agcaccacca tatagaaggt tagaaacaga ttttatctgc
     2161 tttatatcgc catctggcaa taaaatccgt tttttgatgg gattaaataa acatgacacg
     2221 gattttaaga ataattcttt ctttgacacc gtatatgtgt aaagcttatt ttgcttgttt
     2281 aaccaatata aagctttaaa agtcctcaaa cacctataaa ttgttgagtt tggaagtcca
     2341 gtgacttgtg aaagcaaatc aacatctact actttttgac cttttgtcaa taaaaaggca
     2401 atccacgtta attgttcgct aggtgttaat tccttaggga cttcagtatc attcgcattg
     2461 agtactagtc ccaatggagg gaagaagagg tttcccttaa agtctacaaa cggaactcta
     2521 gcttgaagta attgcttttt ttcactgtct gataacttcg aaaacaccaa aacaacatcc
     2581 atattggctt tttcacccat agtgcgagcc tgagtaacaa atgaactcaa actccccctt
     2641 ctcttttctt taatcaataa aaatgattcc ttatgaaaag tcatttgagt atactcaaac
     2701 ctttttacaa aactgattgg taaagtcaaa gtcagttcct caatactgac atcaacataa
     2761 aaggattgaa aaattgacat tatctttttg acattcatgt tttttcctta ttctatcatt
     2821 tttattatat tttatcattc ggtataataa aatataagtt ttttgataaa ataaccaaaa
     2881 actactccct atcccctctc acattaccct acatatcgtt tgacatgcga ctgatagttc
     2941 aggaaaactt caaggagaac ttttctctca tccactatgc aggacttact atttcacttc
     3001 tactcctata ggctcaattt gacacttttc tttttcgaat tgctcatatg cctcctgaat
     3061 agtgagttcg atttatccaa atttattttt gtctattttg atgaatactt ccacgaagat
     3121 agtctgaaaa tgaatttgca ccaattttcc ttctcttttt aagcatatta ttccagatat
     3181 gattgccctc ttgttcagta ataaattacg ctttaaacgc ttcaatcagt atatctcctg
     3241 ttgtcatatg ttctaaagaa aattcttcta catatgattt aacatctctt aggttattac
     3301 ttcctaatat cccattatgc tttttcgcta aggaaataga agccgcttct cccttaccaa
     3361 taatcttgtt actatcatga tttcttgtta aatctctata taatgcgtat tcttcagttc
     3421 caatgtctat gctcacaatc tcagctgaac ccttagctac caactgatct atcctagatt
     3481 ttaaatgggg aattgtaggt atattgattt catcatacac ctcttgtgga ataacaattt
     3541 tacccgaata gagcttttct aaaagatgtt cagtaccaac ccataaaaat actgaaatac
     3601 aatctgcatc aataaataca cgactagtca aacgacaact cccccctctt catctagccc
     3661 atatacaata tcatatctga aagcatctag taacagttcc tcatacttcc cttgcgaaat
     3721 tctgttattt tctaaaagtt gttcagttga attaacatat tatcctaata tcatttactt
     3781 tttactttct gacaaaggac gatataaact tgtatcatag cctaatcttg aagctgtctc
     3841 tataacacta atatccatat ttttaatttc ttctgcatca aggtatccat cattcctcaa
     3901 tctatataac ataactttat gactgatacc ataaaactga cccaatttta taatatcttc
     3961 tacttcaaga tgagttctat tggcattttc tctaatttcc tcaaccatcc tatacagtga
     4021 agatgggaaa attaaaaaat aagaagcaaa ctgatccgct tttctttcag tttcatctcc
     4081 ttcaccaatc aagataagac tgactgaact cttcttcacc tcatcataat aaagatgata
     4141 cagttcatgt gctaaagaaa atctttacct tcctaatgac atgtctgaat tgactgcaat
     4201 gagactgaac tgagttcctt tataacagac tccgctaata ttctttccga gtccataaaa
     4261 taccagcgtc aaattttcta tcttttgtac caatttaaaa atatctatcg gcgattcacc
     4321 atcagctccc aacttttttc taagatttga agctttatta cttaaatcca ttcgtgatat
     4381 tcctttcacc tttttccatt ttggcaatca tgctttgatt caaagacaaa tactcagcaa
     4441 tcttatcttg agtaagattt gaagatattc taagttcttt tattcttttt ccaacatcac
     4501 atacatttat cacatacatt tatcatattc atacacctct cataaaaaga atagcacact
     4561 tttgtcataa ttttttaaat aaaaaaatta tgacaaaaca aggaagcaat ttattgatgc
     4621 tgcttaaaaa tctaaaattg atgagttcct atcaaaaatc gtatcttcaa cctcaaaaca
     4681 gtacttaaag ctatccgact cggtttacat tgtcaaattt agattttatt tgagcataac
     4741 tttctagttt gctttctgat ttttgtttaa tatagtagca aacattgaag gaaatatctc
     4801 cacaaaaaaa cgcatactat taagcttttt caagacctaa taatatgcgc tgttctgatt
     4861 tgaaagacat tccattatta ttttactgta atcaagccat ctggctctac tgtgaattct
     4921 ggcttgtctg ccagtgttcc gtctggtttg aggtagtacc agcctgttcc gtccgctgac
     4981 tggataaagg catttgatac catggcgcct tctttagcgt ctaagtagta ccaagtgtcc
     5041 ttgtacttga cccagcctgt cttcatggca ccttcttcgt tgaaatagta ccacttatca
     5101 gcgattttct tccagcctgt agccatttcg cctgagttgt cgaaccagta ccagttgccg
     5161 tctgtgtgct tcctccagcg gtctgcaagc atatagcctg aactgtcaaa gtagtaccaa
     5221 gtgccattga ttttctcaaa cttgtctttt ggataagagc cgtctgaatg tacgtaccag
     5281 tagccagtgt cattcttctg ccagcctgtt tcaatcgtca agccgttctc aatatcatac
     5341 ttaaactgct cacggctaat gccccatttt gccaagtaag ggtatggatc cacatggtct
     5401 gagtggttgt ttggttggtt attcgtgcaa tactcgtgcg ttttaattcc agctaaactc
     5461 cctgtatcaa gcgttttcgg caaacctgct tcatctgcta gattgcgtaa gagttcgata
     5521 taaaggcggt agtccgtcat gaactcttct ttagttgaat ggctttcaat cagttcaacc
     5581 gctgcatagg tttcagcatt ccaaccgccc ccaacgtccc aggcaccatt atcaacaggt
     5641 cctacctgca tgatgcaacc gttcccaaca atgtgcgaga aaaaacctaa ttctgggtct
     5701 ttccgccagt gataatccgc ttcattctgt acggttgaat gcggattccc agttgagtgt
     5761 gcgtgtactt gcctatatgg ttgcacgccg acttgaggca aatctgttct taatttactc
     5821 acattaattt ccatattcta ctccttatca attaaaacaa ctcatttttt acaatccaga
     5881 accagaaact cctttatttc taccttacaa agaagacaat cttagtcacg attaggcttg
     5941 tagatagaac ctcaaaacgc actattttga cactgtaaat aggactgaca aggtctgcat
     6001 tctatctaca ataacacccc agactaaaaa gcttttcaaa agtatatttt tacagtctct
     6061 atatgtcctt ttcataaata ctatacttta ttatatcata taaaagaagt caaaagtctg
     6121 ttaaactatt ttcaacacca aactaaagaa gagaacacaa gttttttcga tgttcactag
     6181 aggaaatgga ttttattcag taaatccaac taggattgca ctttggttgc caaaattgcc
     6241 tttccttctt ttatcaaggg atgacggaat agtgagaagt acagttgaac tgtcatggca
     6301 acccagataa gaggttcaca aaggataaca cccttatatc ctgcccaagg aataatcaaa
     6361 accacaaaaa cgatttttcc gattagttca ataaagctag aaactagagg aaggatcttc
     6421 tgccccaagc cctgcaagca attgcgataa atcaacaaga ggctcaaaat gggataaaag
     6481 gctgaactga tttgcagata gagacttcca ttttctatca agtaaccatc tgtcgaacta
     6541 gccaagaagg aaaccaaggc tggactggca aaaaagagga aaatacaaac aaaaactgcc
     6601 caggatatac ttaaacgact gccgattcga agaccttgaa caatgcggtc aggtcgctta
     6661 gctcctagat tctgagaagc aaaggtcgtc attgatgcag aaatagcggt cataggaaga
     6721 agggcaaagg tcataatgcg tcgagctgcc gtctgggcac taataatcac tgcaccaaat
     6781 gtattaacag aaaactgtaa aatcacactg ccgatagata caattgaact catcaagccc
     6841 atagccaaac cttgctccaa gagatccgcg tacaagcttt tgtcccattt gaaatgttta
     6901 aactgtggca agagttctgg cacactttta cgaatataat aaaagcagag aaccgctgat
     6961 aaaccttgcg aaataatggt agcaagtcct gcggattgaa ctcccagatg caattgcgta
     7021 ataaaataga gatccagaac cacattaacc aaggcagaga aaatcagaaa tcccagggct
     7081 gctagactgt caccaataga ccgcaacaag cctgcaaaaa gattataagc aaagctgaca
     7141 cctacacagg tcacaatcat agaaatatat tgataagatt gaggaagaat ttctgcagga
     7201 gtatctaagt attgcaagag aggatacaag ccaagaaagc ccagcaacat aactagaatg
     7261 ctcaaaagag cacctaaaat ccaggtggct gctactgctt ccttgatttt agtgaaattc
     7321 cgagccccat aataacgagc aatgacaatc cccatgccat tgccaacacc aagtgtaaag
     7381 cctacaatca ggtcaaaaat cgctgtcgtc gctcctactg cagccaagga ttcttgacca
     7441 agaaatcgtc caacaatcaa gacatcagca gtgttataga gctgttgaaa aatatttgat
     7501 agcaagattg gaaaggtgaa gcttaagagc gagggaagaa tcggaccatg tatcaggtcc
     7561 actgttcgtt ttttattcat aaagctatta tatcagcttt ccagaggagc gacaagaaac
     7621 agcaaactta tatatagcgg aatgaaataa ggacagtcaa atcgattttt aacaatgttt
     7681 tagaagtaga tgtgtactat tctagtttcg atctattata gttggttgag tttggaatag
     7741 tacgctgtag ctgctaaaac atttctagaa attaatttga ctttcctaat aaagttgttc
     7801 atatcttatt tcaagctact atatataatc taaaaacttg aatcaaaaat cgaaaaagta
     7861 gcggatttct ccactgcttt aacagcttat tcttcaattt cgatttcaag ttcatcgcct
     7921 aagtcaagcg gaacttcttc attcactgct tcttctttct ttggctcatc ttttttgttt
     7981 tcagtatctt gttctgaaac ttcttctcca tcaatcaagc caaatttaga acggacttgc
     8041 ttatcaattt catcaaagat ttctgggtgc tctgccaagt atttcttagc attctcagaa
     8101 ccttgcccaa ttttttcatc tttgtaagaa taccaagccc ctgctttttt gataatatcc
     8161 aaatcgcttg caatcttcaa aagctcacca gtcttagaaa ttccttctcc gtacataatt
     8221 tcaactacgg cttccttaaa cggtggagct accttatttt ttacaacctt aatcttagtt
     8281 tctttaccga cattggtttc tttttgatca ccagttccct taatttgtgt attaccacga
     8341 acatccaagc ggactgaagc atagaatttc aaagcacgtc cgcccggtgt tgtttctgga
     8401 tttccaaaca tcactccaac tttttcacgc aattggttga taaaaatggc aattgttttg
     8461 gttttattga tagaggcgcc aagtttacgc atggcctggc tcatcatacg agcctgcaaa
     8521 ccaacatggc tatctccgat atctccatca atttccgcac gaggaacaag ggcagcaact
     8581 gagtcgacta cgacaagatc aactgcacct gagtcaatca attttcccgc aatctcaaga
     8641 ccttgctctc ctgagtctgg ttgagacaag agcaattcgt caatattgac accaagggcc
     8701 gcagcataag ctggatcaag ggcatgttcc gcatcgataa aggcagcaat cccaccttct
     8761 ttttgcgctt gtgcaactgc atgaagggca accgttgtct taccagatga ctctgggcca
     8821 tagatttcga tgatacgtcc cttaggataa ccacctgagc caagggcaat gtcaagagct
     8881 aaagaacctg agctcatcac ttgcaccttt tgctccgcac gttcacccaa acgcatgatt
     8941 gatcctttac caaagtcttt ctcaatcaat ttaagagcat cattcaaggc cttttcacgt
     9001 tctgccccaa atttttttga aatttcttct aatttttttg gttttttcgc cattctattc
     9061 tcctacattc taatgatcct cagacctatc tactattata tcaaaagtta gtcacttaat
     9121 aaagccttgc gaactaggtt aaaggcatgc ataaccgcaa tatgacgtac atctgctcgg
     9181 cttctgcctc caatattaac cttgataacc tcagttcctt gctcttgcgc caagcctatg
     9241 aagactgtcc caactgggtg tccttctagg ctatctggtc ctgccactcc ggtcaaacta
     9301 attccaaaat cagactgggt cttgcttcgt gcctgctcag ccatcttctg agctgtaaat
     9361 tcagacacca caccatgttc ttccaaattc ttggcaggaa tatccaacat ccttgatttt
     9421 tcctccaagc tataggtcac aaaaccaccc ttaaatatac ttgaagctcc agaaaaattc
     9481 gccacggtag cttggaaaag acctgccgtt aaactctctg cagccgcgat ggttttccct
     9541 tgccttttca gttcttctac cacaatgctg gctaaactag tttcttcccc ataaccatag
     9601 caaaagtctc gtaaagaaat tccttcgaaa gtctggcagt ccaagatttg attttccaag
     9661 atatccagcg cttgattcgc ctcttcttga ctgctagcct ttgttgacag acgtagagtg
     9721 acttctcctg tcttggcata aggggccaag gtaggatcga tctgattatc aattaaatca
     9781 gccaaaatcg taaccaactg gctctcgcca atcccaaaga aacgaagaac tcgggaatac
     9841 agcttgctcc ctgtcatcaa cttgggtaga agttggttta agaccatggg tttcaattca
     9901 cttggcggac ctggaaggac gacataggtc actccgtcta cttctaattt tcctccaaca
     9961 gccagtcctg tttcgtttgg cagtggaatc gctccttcta caatttgagc ttgtctttcg
    10021 ttattcggtg ttcgggcata gtctggtcgc agggcaaaaa agatatccaa cttctcctga
    10081 gcctgaggat caaagactaa tgctttccct aaaaatttag ctagggtttg tttggttagg
    10141 tcgtcctcag ttggccccaa accgcctgtc aaaatcacca gactgctacg ttgactggca
    10201 atctcaagca aagacaagag acgaacttca ttgtctccta cagccgtctg aaaatataca
    10261 tctaccccaa tctcagctag tttttccgac aaaaactggg cattggtgtt gacaatctgt
    10321 cctgtcaaaa tctctgttcc aacagcaatg atttctgctt tcatgtttcc tcctacctat
    10381 ctattcgtat ttttttgaaa aaatcgcagg aattttccta cgattgattt ttttatttgt
    10441 atcaaaagtt aattatcttc atcaccaaca ggtgctctgc caaataaatc ttcaaataaa
    10501 accgcattgg tttcaagctg agtaacttct tcttgtccca aagaacgtcg gagtatattt
    10561 tgcatttcca acatatgtgc tctcgaaaca atctggtaag aaacaccttg aagtatctct
    10621 ccttcaccct gcaactgctg agtttcaatg gttttaaatg aatctttata gcctagcaag
    10681 ttagggatac tttttgcaga caaatcaata ttggtctgca tattgtcact caaagctttt
    10741 agaatctctt gataatgacc aacgctattt aaactgagag ctttttccat gactttttga
    10801 ataacttcac gttgacgttt ttgacgacca taatccccct caggatcttg gtaacgcatt
    10861 cgtgcataga ctagggcttc ttctccccca atatgttgct ccccaacacc gatagaaata
    10921 gtattaaatt cttcttggtc actgatagaa attgggaaac ctaggatatt attgactgta
    10981 atacctccta ctgcatccac tagtttttgc aaccctctca tattgaccat cacatagcga
    11041 tcaatatgga tattcatcat tttttgaatg gtttctatag caagctctgc tccaccatct
    11101 gcatatgctg agttcagttt cgcttcatga gcctgaccat tccctgattc aatgcgcgtc
    11161 agaatatccc gctctaaact catcattgtt gtttttttcg ttttaggatt cactgtcatc
    11221 aagatcatgc tatcacttct accgacccaa gtttcagttc gttcaacatt tccggtgtcc
    11281 actcccatta acagaatggt tagaggttca gtcgcttcaa taaccttggt ttcttcaccg
    11341 atttttttat aggttttagc taaggtttct gtcccttgtt gataaatagt ataagcaaaa
    11401 acacctactc ctactacagt tacagaaagt aaagctagca ccattccaat aattttttta
    11461 accatatttc tactaaccta tcagtttacc catcaagtaa acatcgataa atttcccttc
    11521 ttctatatat gccccacgct cttggctacc ttcaatgaca aagccatgct tttgataaag
    11581 atggactgct gcttgattac gagtttggac agtcagttgg agacgacgca gaatgccact
    11641 tgcttgtgcc cactctatcg cttcttctag caacaaactt cccaagccat tattccaata
    11701 tctttttcca atcacaatga agagttctcc aatatgacgg actctcttac gctggtcagc
    11761 tgtaatattt acaataccag caattttgcc atttaagaat gcaagtaagg ttatctgatt
    11821 gtccgaacta gcttgcttgt tgaggaatat ttccatctcc tcactagtca agagaatacc
    11881 atctccgtct aggctggtaa agtctgtctc caaactcaca cgatttaaaa aggccactaa
    11941 ttcagctgca tctttgggct ctgcttccct aatgagcaat tcatactcca tattgaagct
    12001 cctctaacaa tttctcagca cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg
    12061 cttcttttag aatttccaat tctaaataag catctggcaa ggcatctcct aagagattgc
    12121 cccactcaat aacagtcacg ccgccaccaa agataaactc atccaagtcg atagaatcag
    12181 catctccttc aatacgataa acatctaggt gataaagtgg aagtcgacct tcatactctc
    12241 tcacgatagt ataggtggga cttttaatca tttgagaaat ctgtaatcct tttgcaagtc
    12301 ctttagtaaa ggtcgtttta cctgcaccca gttctccagt taagattaaa acatcattct
    12361 ttgctaatag atggcccaaa cgctccccta aggcttgcaa ctcttcttca ttttttgtgt
    12421 acatactctt attataccaa aaacttttct tttgtgtcta ttttcctact aaacttatca
    12481 tcataacatc cataaaaaac aggctttctc taaaagaaaa tgagcgtaac aatgaccaat
    12541 acaagatctc ggaaaatatg accataaaag gaaacttcct tcttaaccga atttgggaca
    12601 agataggctg caaaaaacaa gcccagtcca atataaatca gaagtgagac aatggtcatt
    12661 ggatttctta agaaaagaag tgttgctaaa atagtcacca acactgtctt ttttctgtct
    12721 agcatagcaa gaaaatcgcg cacgtatttt ttcaagggta aaaaaatcag caaatctagc
    12781 ccaaatagga aaaagaagga tggcaataaa aagtcaacta attcttgctg cagcgtattt
    12841 ttgatgaaca agttatctga caaaacaaga acagctccta acaaattaat taagagtaac
    12901 atactgtaaa aaagcttcac agacttctta ctggctagga cactatggac ttcttgctta
    12961 cgggtataaa gataatttac tccagcacag attcctgaaa cgaaaaccat gcttccgatg
    13021 aaaaaaactg tactttgttt aaaggacaag atgcattcct tccataggaa acagctactc
    13081 aaactgattt gaattaaagc taacaaaaat aagattctca ttgatttcat cttctctctc
    13141 ccttcctacc aatcattata ctaggagaaa agagagaact gtttctaatc ttctcaaatg
    13201 tctctttaag acgctaaaca aacactagag actaatactc aatgaaaatc aaagatcaaa
    13261 ctaggtagct agccacaggt tgctcaaaac actgttttga gattgcagat agagctgacg
    13321 tgatttgaag agattttcga agaatataaa tttgaaatca tgaaaatccg tcaaacgggt
    13381 ggttgttttg tctcgcacct cacggagcga gacggactca gagtcacata attataaggc
    13441 tgatagtatt aatctaacta tcagccttac aggttattta acgtttcaga aaaactataa
    13501 tgtcaagatt aactaaacag tatctaattc cttcaaataa ttttctatct tcatcaacat
    13561 taaaggattg ttataaatct tacataactc tcttgcttct atataataat ttttgacttg
    13621 ttctctgtct agaaatttgg ctccagcatt tcctacaaga ataagtagag gagccaattg
    13681 gtagcttgtc tgtctttgtt tacagagttc aatcgtttca agagcttctt ggatggcttc
    13741 attatatttt tcctttgata ctaggtagtg agcgtagttg taacgaactc tgatgtagcc
    13801 aaataaaaac tcttgatggt ccaaattttt tgtctgatac aactctatta aatgagagta
    13861 gtttgcctca tattcttgtt cacgacccac taaggaatag aaattagata gagtattcaa
    13921 cgcctttaaa taaatcagag tatttgaaga gacttttaat aatatatttt ccaatgacga
    13981 aattgcctca cacttactgt catattgata gaagtcaatt atagatttaa tccattcaag
    14041 gtaagttcgg tcttctaatg ttagaaaagt gcttcgttct acctctattt tataaagata
    14101 ttctaaatcg tcataatttc tgtcatctaa taggcgagca gatagatgtt tgaaattaga
    14161 gaggttagac ttaacttcga tttgttcatt gaaaaagtaa tccaaaggga cttcaagtcg
    14221 ttgagagagt ttgaataaca agtctgcgga gggaataaaa tgacctcttt caattttact
    14281 aatctggctt tgttcacaaa ttccttctgc aagagtttgt tgggagagtc tcaactcttt
    14341 tcttttcaat ctgaatttct ctgcgagtgt attcattaaa gataataaac cttcctattt
    14401 gcttaatttc attataaagt ttttagttca aaatagcaag ttaaaggaat aaataattct
    14461 ttatggtaat aaacaaaaaa aaaagttaaa aattacataa aaatacttga ctaaataaaa
    14521 tatatctgtt agaataaaaa caaggaaaaa gaaaggggtt tcattgcatg agaaaaaaac
    14581 gtggaattaa aaaattagtt acatttgcat tgctaggtgt ttttatgttt agtaatacaa
    14641 ttccttacca acagtttatt cagaagaata aacaattgga gattcgagtg taatcgcaaa
    14701 agaagtccaa tggtcttgat gttgggaagg ctgattaaaa cccgatattt tgcacgagaa
    14761 tgagagaatt ataatttatc tgaaaaaacg aaaaatatag agcaacttat ttaacttttt
    14821 ataaggagga gttattactt atgaccaact ttaattcaaa cgaaaaattt tgtggaaaaa
    14881 gtttaaaatc attgtctgct gatgaaatga gtttaattta tggtgcatct gatggtgcag
    14941 agccacgttg gacgcctact cctattattt tgaaatcagc tgcagctagc tcgaaagtat
    15001 gcattagtgc agctgtttct ggtattgggg ggctagttag ctacaataat gattgtttgg
    15061 ggtaaattaa aatgaaaaat gattttgtaa tcggaaagag tttgaaagaa ttatctcttg
    15121 aagaaatgca attggtttat ggtggcacag atggtgctga ccctagatca acaattatat
    15181 gttctgctac attaagtttt attgcatcat atttggggtc agctcagact cgttgtggca
    15241 aagacaacaa gaaaaaataa aatattcaat tttaaaaata aaagttgctc tttattttcc
    15301 tctctcgtaa ctaataattt tgagagaggt tttttttaaa acaatagtaa gtcgtatagg
    15361 tttgaggtaa gtaaatgaaa tataaaatta aaaatgtgca taaaacattg tttattaagg
    15421 aaagatatca aatattatct gaacgaaatg ataattcctt aaataacttt tcagaaataa
    15481 ttggcgttct acaatgtcaa ttatttctga aaaaactttt gaagaaatgt tgaaattaaa
    15541 taattacaat aaaaaaatat tttctaacac tgtgaactat gattataccg aggaacagat
    15601 aagactatat tcagaatatg ccaaaaattc ggaatggtat aaatttgcgg agggttcatt
    15661 tgaaatattt agaaaacatc cccaaagaat taattttaag aaagattttt ctagaatttt
    15721 ggaacccttt attattaatt tgcttaaatt aatcaataat tatctagaga ataaagaata
    15781 cgagtggatt gacaagaatg gaaatatttt ttcctctcta gtattttatt tagaagattt
    15841 aatctatcct tggattgtta aacctttggt tttagagata aattcattgc gtgaaaaagg
    15901 tttacttgaa ggggaatcgg agcagcaacg gtacaaatat tttataacat tgtttgacaa
    15961 ggaagagaat atattaaatt tttataacaa atatcccgtt ttactgaggc aaatatcgga
    16021 gtcttgtctt cggttctata cttattttat agaaatttta tcaaatttag aaaatgattt
    16081 tagtgtgcta gaagaagaat tagggctaag ggggaaatta aatgatataa aatttggaaa
    16141 gggtgataca cacagccaag gaaaaactgt tttgatactc ttctttgatg acgcgaaaat
    16201 tgtttacaag cctaaaaatt taataatcaa taactcacta aatactattg ctgagtatat
    16261 ccgaaaggtt gatgaaaaaa ttaggataag aatacctcga actattgctt attcggatca
    16321 cagctatgaa gaatttattg attatctacc tctagagcaa aagaaaaaat tacctgaata
    16381 ttattataat tttggtgtgc ttttagcatt tatatattta tttaatggga gtgatataca
    16441 ttttgaaaat ttaatttcct atggagatat gcctgtaata atagactttg aaacaatgtt
    16501 acagcaacct ctatttgatg ataaaactgg tcagagtttg ctggataccc tgtttcacag
    16561 ggtgactcga actttgcttc ttccaacaga gggagtaaaa agggaggatg gtcttgatgt
    16621 tgagatgagt gctcttacag gaaattttaa gaaggatgct tttaatggtc aagttttaat
    16681 taatttaaat actgataagg taaagtttga tattgggaaa attgattttg aaggtgggaa
    16741 aaacctgcct gttcgggatg gtgatataga atttgataag tatataaaag atttcaaaaa
    16801 aggttttagg gatttttatc tgatatttga agagttaaat aaaacagaag aatttaaaat
    16861 gctattaaaa gcaaacttgt atggtttaaa gacaagggta ctttttagag acacaaatag
    16921 ctatgcttca gtactatctt ttttatatca tcctgatttt tatgaagaaa tgttagatag
    16981 agaaaaagca ttggaaaatc tctggagcaa taagttttct aatcaaggta ttgtagcaag
    17041 cgaatgtgaa caaatgaggt tattagatat tccgattttt tatacagata caaatatcaa
    17101 tgaaatctac gatgattttg gaaatcattt tatttcccta catcaatttt ctggatatga
    17161 ctattttatg aaatatttac ctaataataa tttggaaaat ttagaaaagc aacttgatat
    17221 cattgaaatt tattttccaa gctttgatca gcgaaaaaaa ggatataaat taaacttatc
    17281 taatagaaaa aaactcccaa atgaaagttt agttactatt ctgcataatg aagtagaaaa
    17341 tattgcagac tctttggtta ttaataatat ttatgacgaa tatccaattt ggagtatacc
    17401 tgttaatttt aaaggttcta aatggtgtct tgaacaaacg ggtaatgata tgtatagggg
    17461 tagagctgga atattactgt ttatgtacta tgtaaaatta ttgaaagata aatcatcata
    17521 tactcaactg tacaataaaa tgttatctgc aattccgcca tctgtttctt tatctaagac
    17581 cacatttggt ttaactgggg atataggata tttcattgtt ctatccatta tagaggatta
    17641 cgatacaaat actctcgcat gcttaaatta tataaagagt gttttaactg agcttgaaaa
    17701 gactgatttt gcaagtgttt caaacaagtc tgactatatt aatggtcttc tacctttaat
    17761 taatacactg gtaagatatt ataggagagg aatagagaag gaacgtgttc taaggctagt
    17821 attaagttta ggtgatacgc tatataatga tgtaagcgag agagataata gtaattttgg
    17881 atatagtttt ggccatggac tatcaggtgt aatttttaca ttaaaaaata tttataaagt
    17941 gacaagactt aaaaaatata aagaattaat tttacaacta gttcctaggg agaaaatcaa
    18001 aattcattct ttgaagtggt gtagtggaga atttgggaca ttagttaatc atccccaaag
    18061 tgttccagag ggaattgtag ctagtttaga taatgataca ttttgccatg gaagtatggc
    18121 cataataaat ttttacatcg actacatgaa agaaatggat actagtatgg aattggagtc
    18181 tttattgtgt agtgttgtaa tgaataaatc aaaagaagga gagtatcgta tcgtccaaac
    18241 aagcaatttc ccagattttt ctttgtatac aggtgtgact ggtattgctt atactttttt
    18301 aaggtatatc gcactgaatc agaatgacaa aaagatagtt atcccctcat tacttgaaat
    18361 ctagcttaat ttatagtttt gtttctaaaa tagaggtgtc cactcattaa gcaatataaa
    18421 aataccaaga ttgactagtt taatatgtaa ttctataaaa tatttttaat agtgtagctt
    18481 ttcgttgaga taataatata ataaagaaaa gttctattct aattgctaaa cggcttgagg
    18541 tatatgctac tgttatagaa atgattttaa actaaaatca aaattactcc aaaaatagta
    18601 ttgattttgg tttaatacaa aacatatgta ataatgtgag tcaacaaaag tctgtttttg
    18661 taccatacta tcttgaaaaa tctactaaat tcaaattgag aggatgaatt aaaatgaata
    18721 aaatatttat atatgcagga gtgcgaaatc ataactctaa gactttagag tatactaaga
    18781 gactttcaag tatcatttct agtagaaata atgttgatat atctttcagg acacctttca
    18841 attcagagct agaaatatct aattctgatt cagaagagtt gtttaagaaa ggaattgata
    18901 ggcaaagtaa tgctgatgat ggaggtgtta taaaaaaaga gttattagag tctgatatta
    18961 taattatctc ttctcctgta tatttacaaa acgtatctgt ggacacaaaa aactttattg
    19021 aaaggattgg ggggtggagc catctttttc gattagctgg aaagtttgtt gtaacattag
    19081 atgttgctga gagtaacggc tctgataatg tgtcagaata tcttagagat atattttcat
    19141 atatgggagg acagatatta caccaagttt caattaccaa ttcactcaaa gatattgcag
    19201 aggctcagtt gatggaggca acttataaaa ttgaagatgt acttgaaggg aaaattaagt
    19261 acaaaacaac ggattatcaa gaaagagctt accagacatt aaaattaatt ttagaaaatt
    19321 atgattccga acattttgag aagatgtatt gggagaaaaa acgccttttt gaagctaata
    19381 gtttagagga atggtattat gttgaaaata ttaaataact ctgtcatata tttatgtttg
    19441 attccgttat tgttcctatt attgataatt tttccaaatg attcattaat ctattatttt
    19501 cgattgattt taatttcgtt aatatcaatt acattacatg aactaggtca ttttttagtg
    19561 ggaagatgtt tatcttataa actagagatg cttgctactc cctttttctt ctatttcaga
    19621 aaaaaaatat atttcaaatt tccagtgtta ttagcattcg gttattgtca aatgagtaat
    19681 agaaacatta ctaatgaaaa aaatagtgat aggaatttgg tgttctactt ctttggggga
    19741 ggtggagcta acctaattgt cgcaatatta gcacttttgg gatttgtgcc gtacgcatca
    19801 gaatttttta ttttgaatat aattcttttt ctagttacgg tatgtttacc aattgatgga
    19861 acagatggca atgctattag agagatagtt ttgtattcaa aagattcaaa aacatatcag
    19921 agattctttg cgaacagtct ctataataat ccttatataa caatcgacga ttttgcaaaa
    19981 ttaacctcta aagaaaaatc ttttttttca aaatttgaaa aatgtttgat aaacctttac
    20041 tttgaagtga aaggtgaagg gtcagcattt acaattgcta atcatgaagt ttttgattca
    20101 aatattcagg aaaatattat ccatgagtac tataaattac tacataaatc ttctgattgg
    20161 attattccac agaacttatc tttagaagaa gttgttttta ccttgtcaaa ctatatttac
    20221 tcgaaaaata ataaatattt agaaaagatt aagtatctaa agaaattagt agattttaga
    20281 caagaagaaa ttatcgactt tattttgaac aaggaggaag tattgtgaaa attccaatga
    20341 tatatcaaat ggaaaattca gaatgtggat tagcatgctg tgccatgata ttgaactatt
    20401 ttaaatatga gatttcttta aatgaactac gtgaaatcta cccatcatcc agatctggat
    20461 attctctcct atctataagt aaagttttag gagattttaa tataagttct catgctttta
    20521 aagcttcggt aagagattta aaaccgctca gtttcccact catttgcttc tgggagagtt
    20581 ctcattttat tattcttgaa aaaattagta aaaacaagtt ttatatttta gatcctgcaa
    20641 aaggcaggca gagaatgtca ataagtgaat ttgaaaggca ttattcaaat atcattttaa
    20701 catttaaaaa gttagatagc tttatgtctc gtaaagataa taagaagtcg cctgttttaa
    20761 agtatttttt taagtatagg aataagctag ggattttatt ttttgtaaca gcattattgt
    20821 atgtaataca atcattagta cctatagcta atagatacat aattgacacg aatttcaagg
    20881 acgattcgta ttcgtctaga atgttattta ctatattatt tatatttact gtttcattct
    20941 cactaatgta tttattaaga cagatatatg ttgcatcctt aaaatatata atggataaag
    21001 agattagcta tgattttatg aaacatttga tatatttacc ttacagtttt tatgaaaaac
    21061 gtactttagg ggatatactt tttagagcta actctattgt ttatataaga gaaatactat
    21121 caaataattt tatagcagct atacttgatt tgttaatgat tgtggtttat gctgtggttt
    21181 tatttagctt ttctaagtac atggtaatct ttttaatatc actaagtcta gctctatcta
    21241 ttgtaatgta tccaatcata aaaatctcaa aaaatttaat tgataaaaat ataaaagaaa
    21301 aggttaatgt tcaaaatatt acttccgaag taatttctaa aaatagtgat attaagctaa
    21361 ctggagaaga ggaattttgg attaacaaat gggataattt taatacaaaa cagctcatca
    21421 taggtcgaaa acttgatata catttatcaa ttgttagtag tataacgaat gttttacaaa
    21481 ttattctccc tgttttgacc cttattgtag gtgtaaatat aaaaacattc gaacaattga
    21541 cgttaggaca aattgtagca ataagtacag tctcaccata ctttatttct cctataattt
    21601 ctttaagtga taactatata caattaatgt tattaaaggg atatttttta agaatagagg
    21661 atgtgtttaa tactaaatcc gaattaattc cagaaagagt cagtcaagat ataaaatttg
    21721 ataaaaaaat agaattaaaa gatatttggt ataaatatgg attatttgat gattatgttt
    21781 tgaaaggaat aaatgttact attaaaaaag gagaaactgt tgctattgtt ggagaatcag
    21841 gttcaggtaa gagtacatta gctaaaattt tattaggttt attagaacct aatattggtt
    21901 caatagaagt tgatggagta gaaaaagaag aaattggtca aacattgtat agaaagattt
    21961 ttggagcagt gttacaaaat tcaaccctaa gttatggtac cttaagagag aatttgacat
    22021 ttggacactt tgtttcagat gaagaattaa tgacaaatct aaattcaatt ggtcttagca
    22081 atgtagttaa atctttacct cttggattag agacaatcat cgctgaagaa ggtaataact
    22141 tttctggagg gcagcagcaa atgatacttt tagctcgttg tcttttgtcg aaaccttcgg
    22201 tagttgtttt ggacgaagca acaagtagtt tagataattt atctcaacaa attacaactt
    22261 cttacttaag tgaaatcggt accactaaga ttttaattgc ccatcgacta gatactatca
    22321 agtctgcaga taagatctta gtaatgcata atggtgaaat tgtagagatt gggacccata
    22381 gagaacttct tgaactagga ggcatttata agcaattgta ttcaaataat tagtttttga
    22441 ttaaaagggt aaatttatga agattatgaa aaaaaaatat tggactttag cgatattatt
    22501 cttttgtttg ttcaataatt ctgttactgc tcaagaaata cctaaaaatc ttgatggcaa
    22561 tataactcac actcagacta gcgaaagttt ttctgaatct gatgaaaaac aggttgacta
    22621 ttctaataaa aatcaagaag aagtagacca aaataaattt cgtattcaaa tcgataagac
    22681 agaattattt gtaacaacag ataaacattt agaaaaaaac tgttgtaaat tggaacttga
    22741 accacaaata aataacgata ttgttaactc tgaaagtaat aatttactag gcgaagataa
    22801 tttagataat aaaattaagg aaaatgtttc tcatctagat aatagaggag gaaatataga
    22861 gcatgacaaa gataacttag aatcgtcgat tgtaagaaaa tatgaatggg atatagataa
    22921 agttactggt ggaggcgaaa gttataaatt atattctaaa agtaattcta aagtttcaat
    22981 tgctatttta gattcaggag tcgatttaca aaatactgga ttactgaaaa atctttcaaa
    23041 tcactcaaaa aactatgtcc ccaataaagg atatttagga aaagaggagg gagaggaagg
    23101 aataatatca gatattcaag atagattagg tcatggtacg gctgttgtag ctcaaattgt
    23161 aggggatgac aatattaatg gagtaaatcc tcacgttaat attaacgtct atagaatatt
    23221 tggtaagtcg tcagctagtc cagattggat tgtaaaagca atttttgatg ctgtagatga
    23281 tggcaatgat attatcaatc ttagtactgg acaatattta atgattgatg gagaatatga
    23341 ggacggaaca aatgattttg aaacattttt gaagtataaa aaggctattg attacgcgaa
    23401 tcaaaaagga gtaattatag tagctgcatt agggaatgac tccctaaatg tatcaaatca
    23461 gtcagattta ttgaaactta ttagttcacg caaaaaagta agaaaaccag gattagtagt
    23521 tgatgttcca agttatttct catctacaat ttcggtcgga ggcatagatc gcttaggtaa
    23581 tttatcagat tttagcaata aaggggattc tgatgcaata tatgcgcctg caggctcaac
    23641 attatctctt tcagaattag gacttaataa ctttattaat gcagaaaaat ataaagaaga
    23701 ttggattttt tcggcaacac taggaggata tacgtatctt tatggaaact catttgctgc
    23761 tcctaaagtt tctggtgcga ttgcaatgat tattgataaa tacaaattaa aagatcagcc
    23821 ctataattat atgtttgtaa aaaaaattct ggaagaaaca ttaccagtaa aaaatggtat
    23881 aaaagtgtta aatataccaa acgtattgag atatgatttg aatatgttac aattagaata
    23941 taaaaatgaa caaagttggg atagtttcat agataatgtt aatttaattg agttggaaga
    24001 gagaattcaa actactattg gaattaaaca aataaacaca cacaatatta ttactattgc
    24061 ccgagaaggg tactctcaaa attatttacc taacacttca gaaaatacat ataattcatt
    24121 acaagtcagt ttagttggag tattactact ttttataagt atggtaaata ttttatgggc
    24181 taaaaaaagt aaatgaaaat aaaatttgga gccctctgaa aaagtaagtc ctacagttca
    24241 actaaaatga gtcaaaagat gaatcacctt gatgtagggg agtttgtctt attgctgcct
    24301 gaacacctcc gttcagagga agaacattat aaatctgttt ttgaagacga cttaaccagt
    24361 cgcatatcta gtcaagatga acgacagcaa atgactgcta cggtaggtta tttagaatca
    24421 ggtcaggatc gttttgtgta taatacgacc cctatttctt accagcagtt tttgaaagat
    24481 ccaatcatca ttgttataac accccaatca actggtccac agtccatttt gttttggata
    24541 gacgcagtac agaactacgt tctctttaat caattgtctg atgcccagga gcttatccag
    24601 agacaaggca ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa ctacatcaca
    24661 ttattggata atatccagag ggaacgttgg gtaatgctag caggagctgt gcttgggatt
    24721 gcaacttcaa tcttgttgtt taacactatg aataggctct actttgaaga atttagacgt
    24781 gccattttta tcaaacgcat tgcaggtctc aggttcttag aaatccatcg cacttatctc
    24841 tttgctcaac tgggtgtgtt tttactggga tttgttgcga gtgtatttct tcaggtagag
    24901 ataggagttg ctttcttagt cttgttactc tttactggtc tatctctttt acagttacat
    24961 gtccaaatgc agaaagaaaa caagatgtcc atgcttgttt tgaagggagg ttaatatgat
    25021 tgaacttaaa caggtgagta aatcttttgg agaacgagag ttattttcga atctttcaat
    25081 gacatttgag gctggaaaag tctatgcctt aattggttca agtggtagcg gaaaaacaac
    25141 cttgatgaac atgattggga aattagaacc ttatgatggg acgatttttt accgaggtaa
    25201 agacttggcc aattataaat caagtgattt tttccgtcac gaattgggct acctcttcca
    25261 gaactttggc ttaattgaaa accaaagtat tgaagaaaac cttaagctag gtctcattgg
    25321 tcaaaagttg agtcggtcgg aacagcggtt gaggcagaag caggctttag aacaggtcgg
    25381 cctggtttat cttgacctag ataagcgcat ctttgagtta tcgggcggag aatcgcaacg
    25441 ggttgccttg gcaaaaatta tcttaaagaa tccacccttt attctggcag atgagccaac
    25501 agcttcaata gacccagcaa cctctcagtt gattatggag attttgctat ctcttcgaga
    25561 tgataatagg ctaatcatta tcgcaacaca taatccggca atttgggaga tggctgatga
    25621 agtgttcacg atggatcatc tgaaataaaa atccttgttt ttaattgcac gatgagttac
    25681 tgaaatatta tcatgaatca agaattggag ttaatttaga attgtacttt attaatattg
    25741 aggtaacttt ttcttgataa aggaagaaat aatggagagg aagttagaat gaaaaaattc
    25801 gacaattata ttattgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta
    25861 ataattgaaa gtttggtaga tgatattttg caattttctc tcagaatcaa taatagtgta
    25921 ggagagattt tcctcctaca accgttttaa aagaaaacta tctttattcc atgttatttt
    25981 gaggaagata ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt
    26041 caaaaattta gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa
    26101 aaaagtagct ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa
    26161 aaagaaatta ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa
    26221 cttgcgattt tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga
    26281 acaggataaa agaacctttt gtgccatatt tttctccttt cgctttacaa ttggattgaa
    26341 cacctttatt gtatcgcgtt tggagttttt ttggtataac cttcgacgca cacccgcata
    26401 gcgggtgttt tttttgtctc gcacctaacg gagcgagaca aactaatagt cacttaatca
    26461 aaaaacgcac catatcaaaa actaaaaagt ttgatatcat gcgtcatgtc ttaaactaat
    26521 tgactatact ttctattcaa atgagctttt aaccaattga ttgagccaat caactcttaa
    26581 aaccaaagag caatttctcg cttagctgac tcttctgaat ctgaaccatg tacaacattt
    26641 tggataatct cattttctcc agcagctttt gcaaaatcac ctcgaatagt gcctggtaaa
    26701 gcttcttctg gacgagttgc acccatcatg gtccgccaag tttcgattac tttgggacca
    26761 gaaatgacac ccacaagaac tggacctgaa gtcatgaatt cacgaatcgg tgggtaaaaa
    26821 ctctgaccaa ccaagtcctg atagtgctgg tcaatcaact cttctgaaac ctgtgaacga
    26881 aactccaatt tttcgattgt aaatccacgt tgttcgatgc gctttaacac ttcacccact
    26941 agccctcttt ttacaccatc tggtttgatg ataaagaatg tttgttccat acccgtctcc
    27001 tttgtcagct tctttctttt attttaccac atttcgtgga aaaatggaga aagttttcag
    27061 aagagagaat gagagaaccc tcgggttctc tcattctctc ttattctact gtttcttcca
    27121 cagtttcaac ggcagtatcc acaactactt ctgttgtttc ttcatttcct tcttcctcta
    27181 ctggaggatt aaggtattct tcttcgttga cagcatgtgg ttcaaggtta cggtaacggg
    27241 ccataccagt accagctggg atgatcttac cgatgataac attttcttta agtccaagga
    27301 gatggtcttt cttaccacgg atagctgcgt cagtaaggac acgagttgtt tcctggaagg
    27361 aagccgctga caagaaactg tttgtttcaa gtgaggcttt ggtaattccc ataaggactg
    27421 ggcgacctgt cgctggaact ccacctgcga taaggacatc tttgttggca tctgtaaagt
    27481 cattgatatc catgagggta cccatgagaa gatctgtatc acctggatcc atgacacgga
    27541 ctttacggat catttgacga accattacct cgatgtgttt gtcaccgatt tctacccctt
    27601 ggctacggta aactttttgt acttcaccga gaaggtacgt ttcaactgac aagacatcac
    27661 gaactgcaag gagacgtttt ggttggatag aaccttctgt cagagcagca ccacgcgcta
    27721 cttggccccc aacttcgaca cgcatacgag ctgtaaatgg aacgacatat tcaccttcgc
    27781 cagtttcacc cttaacaaag actttcttgg tacgagttga tgcatcttct tcgatagcag
    27841 taacttgtcc tttaacctct gtaataaccg cttccccttt aggattgcgg gcttcaaaga
    27901 tttcttggac acgaggaaga ccctgagtga tatcggtatt tgaggcaacc ccacctgtgt
    27961 ggaaggtacg cattgtaagc tgtgtaccag gttccccgat agattgggca gcgattgtac
    28021 caactgcttc accaacttca accgcatcac cagtcgccaa gttgataccg taacagtgac
    28081 ggcagacacc gtgacgagtg ttacatgtaa atacagaacg gatagtcact tcttccacac
    28141 cagcattgac aatttcacgc gccttgtctt ctgtaatcaa ttcatttgga ccaataatca
    28201 ctgcaccagt ttctggatgt ttaacagttt tcttagtgta acgaccgttg agacgctctt
    28261 cgagagactc gatcatctct tttccttctg cgatagaacg gatcaagaga ccacggtcag
    28321 ttccacagtc gtcctcacgg atgataacgt cttgggcaac gtcgaccaaa cgacgagtca
    28381 agtaacctga gtcggctgtc ttaagggccg tatcggtcat acctttacga gcaccgtgag
    28441 ttgagaagaa catttccaat accgacaaac cttcgcggaa gtttgaaagg attggcaatt
    28501 ccatgatacg tccattcgga gcagccatca gaccacgcat accggcaagc tgtgagaagt
    28561 ttgagatgtt accacgggct ccagagtcca tcatcataac gattgggttc ttaggatctt
    28621 gattagcaat caagcgtttc tcaagttttt cacgggcagc acgccattca gctgtaacag
    28681 cattgtaacg ctcgtcgtct gtgatcatac cacgacggaa ttgtttggtg atttgttcga
    28741 cacgtttgtg tgattcttca atgatttcag ccttgtcatc aacgactggg atatcggcaa
    28801 tacccactgt caatcctgca agagttgagt ggtggtaacc gaggttcttc atgcggtcaa
    28861 gtagggcaga agtttctgtc gtacggaaac gtttgaagat ttcagcgatg atatttccga
    28921 ggtttttctt cttgaatgga gggttgagct caagattgct gatagcttcc ttgatagctc
    28981 caccaagtgg caagaagtat ttagctggaa caccttctgt caagttggca ttgtttggtt
    29041 cttgcaagta tggtagcccc tctggcatga tatcgttgaa gagaatttta ccaactgttg
    29101 taagcaagac cttatgtctt tgctcttctg tccaaggctt gttgaggctg tctgttgcga
    29161 taccaacacg tgagtggagg tgaacataac cattgcggta agccataacc gcttcgtcac
    29221 ggtctttgaa gaccattcct tcaccttcgc gaccagcttc ttccatggtc aagtagtagt
    29281 tacccaaaac catgtcctga gatggagtaa ctaccggttt cccatctttc gggttcaaga
    29341 tgtgctcagc agctagcatg aggatacgag cttctgcttg tgcttcttct gaaagtggta
    29401 cgtggatggc catttggtcc ccgtcaaagt cagcattgta ggcttcacag acaagtgggt
    29461 gcaagcgaag agccttacca tcaatcaaga ctggctcgaa ggcttggata cccaaacggt
    29521 gaagggtcgg tgcgcggttc aaaagcactg ggtgttcttt aatcacttct tcaaggatat
    29581 cccagatacg ctcatctccg cgttccacca agcgtttagc tgctttgacg ttttgcacga
    29641 tatcacgggc aacgatttca cgcatgacaa atggtttaaa gagttcaatc gccatttcac
    29701 gtggcacacc acattggtac atcttaagag ttggaccaac ggcgataacg gaacgtcctg
    29761 agaagtcaac acgtttaccg agcaagtttt gacggaagcg tccttgttta cctttaagca
    29821 tgtggctcaa tgatttcaat ggacggctac ctggtcctgt gattggacga ccacgacgac
    29881 cattgtcaat caaagcgtca actgcttctt gaagcatacg cttctcattt tgaacgatga
    29941 tacctggtgc atttaactca agcaaacgag ccaaacggtt gttacggttg ataacacggc
    30001 ggtaaaggtc attcaagtca gatgaggcaa aacggccacc atccaactgc aacattggac
    30061 gaagatctgg tgggataacc ggaaggatgt taagaatcat ccattcaggt ttgtttccag
    30121 acttgtaaaa ggcatccaaa acatccaaac gacggatggc tttgacacgt ttttgtccag
    30181 tagcagtttt caattcttct ttgagttcag caatttcttt ttcaagatct acttgcttca
    30241 aaaggtcttg gatggcttcc gcacccatct tagcaacaaa tgaaccataa ccatattcgc
    30301 gcaagcgctc tcggtattcg cgctctgtca tgatagactt gtgctcaagt ggtgtatcct
    30361 taggatcaat caccacataa gccgcaaagt agataacttc ctcgagggca cgagggctca
    30421 tatcaagggt caagcccata cggcttggaa tccccttgaa gtaccagatg tgagatacag
    30481 gagctttcaa ttcgatatgt cccatacgct cacgacgaac tttcgtacgc gttacttcaa
    30541 ccccacagcg gtcacaaaca attcctctgt aacgaatgcg tttgtactta ccacaagcac
    30601 attcccagtc ttttgtagga ccaaagatca cttcatcaaa gagtccttca cgttctggtt
    30661 tcaaggtacg ataattgatt gtttcaggtt ttttgacttc tccataagac catgaacgga
    30721 ctttacttgg agaagctagg gtgatttgca tacttttaaa acgatttaca tcaaccacta
    30781 tttcttccct ttctattcta agtgaactgc ttattcttgt tcagcagctt cttctgttgc
    30841 ttccgctttt gttgctttct cagcttcttc agcttcaaag gctgctttag cctcttgggc
    30901 tgctttttcg cgggcttttt caaggtcatc tacgtggatg acatcttcgt ccattccttc
    30961 atccaagtcg cgaagttcca cttcttggtc atcttcgtct aggacacgca tgtcaagacc
    31021 aagagattgc aattctttga caagaactcg gaaggattct ggaacacctg gttttggaat
    31081 tggtttgcct tttgtaatag cttcataggc tttcaaacgt ccgttgatat cgtccgactt
    31141 gtaagtcaag atttcttgaa ggacatttga cgcaccgtag gcttcaagag cccaaacctc
    31201 catctcaccg aaacgttgtc caccaaactg agccttacct ccgagtggtt gttgggtaac
    31261 agttgagtat ggtccgactg aacgcgcgtg caatttatca tcaaccatgt ggtggagttt
    31321 gatcatgtac atgactccga cagaaacacg gttatcaaac ggttcaccag tacgtccatc
    31381 gtaaaggatc gttttggcat cgctatccat acctgcttct ttaacagttg accaaagatc
    31441 ttcagaactt gctccatcaa agactggtgt agcgatgtga ataccaagag tacgagctgc
    31501 cataccaagg tgaagctcca taacctgacc gatattcata cgtgatggta ccccaagtgg
    31561 gttcaacatg atgtcgactg gagttccgtc tggaaggtaa ggcatgtctt ctacaggaac
    31621 gatacgagag acaacccctt tgtttccgtg acgtccggcc attttatctc cgaccttaat
    31681 cttacgtttt tgagcgatgt aaacacgaac caacatgtta acacctgatt gcaactcatc
    31741 tccatttaca cgtgtaaaga tcttaacatc acgaacgaca ccatcggcac cgtgtggtac
    31801 acgaagagaa gtatcacgca cttcacgaga cttgtctcca aagatagcgt gcaagagacg
    31861 ttcttcagct gaaagatctt tctcaccctt aggtgttact ttacctacaa gaatatcacc
    31921 ttctttaacc tcagcaccaa tacggataat ccccatttcg tcaaggtctt tgagggcatc
    31981 ttcaccaacg tttggaattt cgcgagtgat ttcttcaggc ccaagctttg tatcgcgcgt
    32041 ttctgattcg tattcttcaa ggtgaacaga tgtgtagaca tcgtccttca ccaagcgttc
    32101 gctcatgata acggcatcct cgaagttgta accttcccaa gtcatgtagg caacgattgg
    32161 gttttgtcca agcgccattt ctccattttc catagaaggt ccgtcagcga tgaaatcgcc
    32221 tttttcaacg acatcaccaa cttttacgag agtgcgttgg ttgtaagcag tacctgagtt
    32281 tgaacgacgg aatttttgga tgtggtaaac atccaatgaa ccatcttcac gacgaacttc
    32341 taccttgtca gcatctgcgt aagtaacttt accatcatac tgagcaatca cagccgcacc
    32401 agaatcgtgg gctgcttggt attccatacc agtaccaacg taaggtgcct gaggattaat
    32461 cagtggcaca gcctgacgtt gcatattggc tcccatgagg gcacggttgg agtcatcgtt
    32521 ttccaagaaa ggaatacatg ctgtcgcaac ggcaactacc tgttttggtg aaacgtccat
    32581 gtagtcaaca atattagctg gatactcttg gttgacccct tggtgacgtc ccatgacaat
    32641 cttctcagca aaggttccat cttcattcag acgagagtta gcctgagcta cagtatattc
    32701 atcttcttca tcagctgtca accaaacaat ttcgttcgtg acaacacctg tttcacggtc
    32761 aaccttacgg tatggtgttt gaacaaaacc atatttgttc aagtgtccgt aagatgacaa
    32821 gttattgatc aaaccgatgt taggtccttc aggtgtctcg attggacaca tacgaccata
    32881 gtgagtgtag tgcacgtcac gcacttcata tccagcacgg tcacgagtca aaccaccagg
    32941 tcctaaggct gacaaacggc gtttgtgaga caactcagaa agcgggttgt gttggtccat
    33001 gaactgtgac aactgtgatg aaccaaagaa ttctttaact gcagctgtta caggacgaat
    33061 attgataatt tgttgtggtg tcaagacttc attgtcctga acagacatac gttcacggac
    33121 attacgttcc atacgagaaa gtcccaaacg tacttggttg gcaagcaatt caccaaccgc
    33181 acggatacga cgatttccaa ggtggtcgat atcatctaca cggccaagtc cttcagccaa
    33241 gttgaggaag tagctcatct cagcaaggat atctgcagga gtcaccgtac gaaccttgtc
    33301 atctgggtta gcattaccaa tgatcgttac gacgcgatct ggatcagttg gagcaataac
    33361 cttgaatttt tgaagaacaa caggctcagt cacaacggct gcatcgtttg ggatgtagac
    33421 aatcttgttc aagtcgccat ccaaatggct ttcaatgctt tcaatcacgc tacgagtcat
    33481 aatcgtacca gcttctacca agatttctcc agtttcaggg tctaccaatg gctctgcaat
    33541 ggtttggttg agtaaacgtg ttttaacatt gagtttttta ttgattttgt aacgaccaac
    33601 tgctgccaag tcataacgac gtgggtcaaa gaagcgagct acaagcaagc tacgtgagct
    33661 ttcagccgtc ttaggctcac ctggacgaag gcgttcgtaa atttctttca aggcttcgtc
    33721 tgtacgagag tccattggat tcttgtggat atctttttca acagtgttgc gaaccaattc
    33781 gctgtcacca aagatatcaa agatttcatc atcacctgag aaaccaagag cacgaaccaa
    33841 ggttgtaaat ggaatcttac gagtacggtc gatacgagtg taggtgatat cttttgagtc
    33901 gctttcaagt tccaaccaag ctccacggtt agggataaca gttgaaccat agcccacctt
    33961 accatttttg tctactttgt cgttaaagta aacacctggt gagcggacca actgagaaac
    34021 gataatacgt tcaccaccat tgatgatgaa agtacccatt tctgtcatga ttgggaaatc
    34081 accaaagaaa acttcttggg tcttgatttc gcttgtttct ttattgatca aacggaaggt
    34141 tacaaaaatt ggtgctgagt agctagcatc gtggatacga gcttcttcta gcgtatattt
    34201 tggttccttg atttcatatc caacaaattc caactccatt gtgtctgtga agtttgaaat
    34261 tggcaataca tcttcaaaca cttccttaag accgtggtct aggaaagctt tgaatgagtc
    34321 agtttgaatt tcaatcaaat ttggtaagtc aagaacttct ttgattcttg aaaaactacg
    34381 acgggtacga tgtttcccgt attgaacgtc atgtcctgcc aagatgattc tcctttgtaa
    34441 ataagttcca agccttgtca atcaggcttt tctaatcgtc atatggttgt aaacccctta
    34501 tcaccgtgtc ctcttgacga attttcagaa tctttaagcc tctgttacaa atgctcaaaa
    34561 tcttgaaaaa aagcacaaaa agagcagcta aatctgactt tttcagaaga tttaactgct
    34621 gtgagccttg tctggacaat atttcagaca aaacctacga caaatgatta cccatattat
    34681 accctattta gctagatttt tcaaggggtt ttagtaggtt tttggtaaat tttttcccat
    34741 agaaaacttg gcatcacatt cgaatcacgc tatggtacaa aaaactgaaa aaactattga
    34801 ctgaaaatca ttttcaaggt ataataataa acgttaaggc ggtatagcca agtggtaagg
    34861 cacggctctg caaaagcttg atcgtcggtt caaatccgtc taccgccttc tataacttga
    34921 tttatcaggt ttcaaatgaa cagaaagccc aatttgaagg gcttttttta ttttccctcg
    34981 aataaatacg tataacttta aaaacttttg gagcgagttt gtggcagagt tctttccatg
    35041 gcataattcc cttttgaaat caattgaaaa aagcttcgtc acgcctggtg acaaaagcct
    35101 ctagtttatt ctgtttcttc ttctatttcg acttctgtga tttggacttt taccttggta
    35161 acacgtccat tcttcacttt atcattggtt aagataaact gtttgttttg gctaaccaat
    35221 tcatagctga gtttctcagt cgttggaata gttcccactc ctgtcaaata ataaccagcg
    35281 atggtatcaa cgtcatcact ttccagttca acatcaaagt aattattgaa atcattgagg
    35341 gtcatagttc cttgaacaat gtaggtatcc tcgccaatct gatgaacatc tattgctgct
    35401 ttgtccgttt catcatcaat ttcaccaaca atttcctcta agaggtcttc caaagtcacc
    35461 aaaccagcca taccaccgta ttcatccagc aagattgcca tttgtctttg ggtatttcgc
    35521 agttctttta gcaagtcatc cacaaaaata gtttcaggta caaaaagtgg atcttgcaaa
    35581 attctcttcc aaacaatatt gtcaaaaccg tccacaaagc ctgccttaag gagactcttg
    35641 gtgtgaatga ttccaattac attgtcctta tccccatcat aaaccgggat acgagaataa
    35701 ttttgtttta aaatactttg gataatggct tgactatcat cctgaatatc caccataaag
    35761 gcatccgttc gaggaaccat aacctctcgt gccatcagtt catcgagcga aaagacacct
    35821 tgtagcatct caatctcatc agcatccaat gtttcttcac tatttgtcag catataggca
    35881 atttcatcac gggtcatctt ttcatccgca tcatcgaatg acataggagt caaatggctc
    35941 aagaaattgg tcgaagcagc taaaagccaa acaaaaggac tgactagttt tccgatccca
    36001 atgataaccg gcgctatacg aattgccaag gcatccttta gattaagagc gattctctta
    36061 ggatataatt ccccaaaaac gatggaaata taggtcaaaa atgccaagga tagaaaagtt
    36121 gccacggctt gtgctgtttc gccattccca agccaagagg caatcacacg tcctagagta
    36181 ttagttaaac tcgcccctga taagattgta atcagggtga ttcctacctg aatggttgat
    36241 aaaaagtggt taggattttc tagtaccttc agcaggcgga tgtagcgtct gtctccttct
    36301 tccgcctttt gttcaactcg ggcacgatta agagaaacca tggccatttc tgtggctgag
    36361 aaaaaggcat ttaataccgt caagataaac aataaaacaa attgtagcaa caaattctga
    36421 ctacttgggt cttccatagt tcttctccta aaatagtatc ttatccttta ttatatcaca
    36481 aaatttaatc caatacatat tattttttct taccgtaact tctcaaagta acttccatct
    36541 ctctcccaaa actggaagtt agttttagaa gttgctattt tttcttagta cctgttctag
    36601 ccctgcttaa actagtaaaa agaactccta catccataag tgacatagga gtttaggctt
    36661 atcttttact gagttacagt tacttctcca gttcggtaat ccagttgaag tcccttttga
    36721 acattgggaa ctagaacatt gaattccaat tctccatccg aagacttggc ttcaatctgt
    36781 gaagctgagg gaactaaatc ctcgtttgaa gcgtagtaaa gggttacacg gtaacggaca
    36841 cgcttgtttt ggtccaaggc tttacgcacc ttgctttcat agtagttttg accagtcgaa
    36901 tactcggctt gtgcctgatt tgcccaggct gtctgaacag caatgttttt aggattgctt
    36961 gttgaggcat caaaaccatc caaaccaccg attaaggcat agcctaacaa atgacctcta
    37021 tcgactgcat gggtataaga gccctttaga ttcttgacct gatgccaacc tggaggagtc
    37081 caagaagttg aaccattccc agtttcttta cgattcttgt actgacgagt ggccttagac
    37141 aagagggcat tagctacggt tggaacagtt tccttgccca ctgtctttgt tttattgtca
    37201 gcgtagggct tacttgaaac cttggcatct agatttgttt tattaccatt gacgataaaa
    37261 gcacctgagc cattccactc cagactcccc tttatttgac tcttgactgc gtctgttaag
    37321 acactctctg ccaatgcttg actaggagct tcagacgctt gttttttctg actaagattg
    37381 gttttgggac tattaggtgc cgacggcatc tgcttgatat aatagctccc tgtagacaaa
    37441 agcaataaca ctagcagtcc gattagtgtc tgtcttgttt ttttgttcat atttctcctt
    37501 atctttagaa aaaggctggt tctccagcct aatttcctgt aaatttatga atcaattcct
    37561 gccattttgc tggagacagg atagcccatg gatcttgacc cttgcccaag attccataac
    37621 ctaccattaa accgattcct agagccagag tacctaaaat cagtactatg atgactaaaa
    37681 gtaaacgctt gactacgtag cttgatttct tattcatctt catcacttgc ctcaatccgc
    37741 tgaatcttag cacctagctg cgccaacttc tcatggaaac cgtagtaacc tctatccaag
    37801 tgaaccaatt taccgaccac agtttctccc tgtgctacca aacctgtcaa aatcaaggct
    37861 gcactggcac gaaggtcagt tgaaagaact tctgctccct gcaaaggctg tccaccaaca
    37921 atacgagctg tatcacggat aatctcagaa tgcaagccca tgcggcgcat ctcttctagg
    37981 tgttggaaac gattttcgaa aactgtctcc accatggttg attcgccttt tgcaactgtc
    38041 atcaaggctg taaattgagc ctgcatatct gttggaaatc ctgggtgggg caaggttttc
    38101 acatgaacag cttttagatt ttctagttga gaacgaacac gaattccttc gtcttcttca
    38161 attacttcaa cacccatttc aagtaacttg gcaatcaagg gacggttgtg ctcccagaca
    38221 gcgtctcgaa tcaagacatc accaccagtc atggcagcag ctaccataaa ggttcctgct
    38281 tcgatacggt cttggactac attgtgagtc gtaccatgaa gtttctcaac accagtaatg
    38341 gttatagtct ctgtaccagc acctttgacc ttggctccca tttcattaag gagaatggct
    38401 aagtcaacaa tctcaggctc acgcgcagca ttctcaatca ctgtcacccc atcagccaga
    38461 gtcgctgcca tcatcaagtt ctgcgttgca ccaacacttg gaaagtccat atagatatga
    38521 gcgccatgca agcgttctgc cttggcttcg atgtaaccag ctgtctgact aatcttaacc
    38581 cccatagctt ccagaccttt caaatgaaga tcaataggac ggctaccaat cgtacaacca
    38641 cctggcatgg ataccttggc atgacccaca cgggcaagga ttggccctaa tacaacgatg
    38701 gaggcgcgca tcttgctgac atacttgtaa ggggcttcct cagtgatgtc gccagtagca
    38761 tccaccttga caagatgagc ttcctcatca aagtcaacct tggcattcaa accaccaact
    38821 acctgattca taataaagac atccgacaaa atcggaacat tctgcaagac ggtctttcct
    38881 tcacttgcta gaatagtcgc tgccaacaag ggtaagactg cattttttgc tccctcgatc
    38941 gtcacgcttc ctaccagacg attatcgcca ccttgaacca caattttatc catactcgtt
    39001 tcctttactc ttgatttcat aataatcctc taagcgcttc ttgccacaaa tgatacaggc
    39061 taataaagaa agaactcagg atgtagccta tgacaatgct aaaaaaggct actaataaac
    39121 gaacttttct tgtattctca tctgtcactt ttaaaacctt ctcccatcta acaagatcct
    39181 ttaaaaggta aaaactcaca taaataaaga gcatatgact acttagagtg aataataatt
    39241 gaaccatttg actattatac catcttctct gtttgtgcgc tagtttggaa acttcactca
    39301 aaaattaggg attgtttttc aagtaatcaa tcgcatcttg tagggtttta acgggcacga
    39361 ttttcatatc cgtcttgatt gttttagccg cttctagggc tgtttggtag ttgtttttcg
    39421 cgtccggatg cgccttttgt tcttcttcgc taacagggtt atcaggagca aagaaaatag
    39481 cagcacctgc cctagccgaa gctacaacct tcttatcaat acctccaatg tctcccacat
    39541 taccatcgcg gtcaatggta cctgtaccgg caacaatacg accattacga agatctgggt
    39601 gagctatttg agtatagata gctagactaa acatgagacc agcacttgga ccgccaatac
    39661 cagctgttga aaagctaatt gggacattgc tgattacctc tgtacggtca atcaagccga
    39721 ttccaattcc atttttgcca ttttccaagg tgataatctt tccttctgca gacttggttt
    39781 gcccatcctc ttcataggtg accttgacgg aatcccctaa tttttgagaa ctgacgtaat
    39841 caatcaagtc tttggaacta tcaaaggtct gatcattgac tgctgtgact gtatcagaga
    39901 tattgagaat ccctttaaag gttgaattat ccgtcacatt caaaacataa actccaaagt
    39961 acttgagttc gatatcctta ccagctgttt ttagtccttg atacttggcc atattttgcg
    40021 atgtttgcat gtagaattga ttgattcgca taaattcaac atcggaagaa ccacctgtag
    40081 tctcctgagc actacgaata tctgtaaaag gtgtcaacca agcataaatc atatgagcta
    40141 aagtggcatg ttgaacacca accgtaacga attgataggc accagcttcc ttatcttctg
    40201 tgtcatttat tttaaggact tggcgaatat cttccgaacc acctggaacc tctatataat
    40261 aaggcaaggg cactacaaat gccaagaaag tcacaatcaa ggccgcaatg acgtataagg
    40321 gccatctaat cttttttttc atttcttatt tcctccaaaa tactctcggg aacatagcag
    40381 gcaatatccc gaccaaactt caaaagctct ctaacgcctg atgaactgat atagagatgt
    40441 tcaggtcgac tatgtaaata aatagtctct atatcagaag acagctgatg attgtagtaa
    40501 tcaaaactgg cttcatattg caaatccgac gcattcctca aaccacgcac tagacaagta
    40561 gcacccaatc tttttgcaac atcgaccacc aattcatcat gagaagccac gacttcaaca
    40621 ttttccaaat gtcccaaagc cttttctagc ccccgtttac gattttcaag agggagaaat
    40681 ccttgtttgt ggggattaaa aaaaataccc acataaagct tatcaaaaag tctgctcgcc
    40741 cgttcaatga tatccagatg cccatttgtc atcggatcaa atgagcctgt gaataagcca
    40801 atcttatctg acatagactg tcaccttact aattccataa atcttttcct tccagatacc
    40861 cagacaggca atttcttctg gaagttcaac ggctttatcc gtctcgcaca caaccataac
    40921 atcttcagaa aaaagctctc tctcagccat tttttcaata tctgctacga tttgttcctt
    40981 ggcataggga gggtctaaga aaacgaggtc aaattcccca gatacctgtt ccaatgccct
    41041 ttctgcatcc atctttagga gttgaaattt tccaacttcc ttggtcatct ggatattttc
    41101 agccacgatg gtctgagcct tacggtctcg ctccaccaaa acagcactgg acatgccacg
    41161 cgatactgct tcgatagata aaccaccact acctgcataa aggtccaaga ctcgtcccac
    41221 ttcaaagtag ggaccaatca tgttaaaaat ggctccccta accttatccg aagtaggtct
    41281 tgtcgtcttg ccttctagtg tcttgagggg acgtccccca tagattcctg atacgatttt
    41341 catactgttt attataccaa attatagaca aaaagagaaa gaaaaccgaa ccttgcggtt
    41401 cgattctcta caaaatattt tcgtaagtat cgcggacttc ttgaggccaa acacttgttt
    41461 gcacttctcc gatgtgtctc ttgcgaagta ggaacatggc catacgagat tgtccaattc
    41521 ctccaccgat tgtcaatggg aatagaccat tcaacaaaga cttgtgccat tccaattcca
    41581 agcggtcttc atcacctgta atttccacct gacgtctaag agtttcttca tctacacgaa
    41641 ttcccataga agacaactca aaggctccac ctaaagactc attccagaca agaatatcac
    41701 catttagacc cttgtagcca ttctcagact cgcttgtcca gtcatcatag tctggtgcac
    41761 gtccatcgtg cggtttacca tctggcaact cgccaccgat accaatcaaa aagacggctc
    41821 caaattcttt acaaatcgca ttttcacgtt ctttcggtgt caagtctggg tagcgttcta
    41881 ccaattcttc tgtatggata aaggtgattt gttttggcaa gatagactcg atgtcatagc
    41941 gggcttcaac agctagctca gtcaggcgaa tagccttata aatcttctca actgtttctt
    42001 ttagataaac gatgttacgc ttaccatttg ggataacctt ctcccagtcc cactggtcaa
    42061 cataaacaga gtgggttgca tccaaggaat cctcatctgg acgaagggct ttcatgtgga
    42121 caaagagacc ctctccttca ccaaagccaa aacgagccaa ggtgtggcgt ttccatttag
    42181 caagtgagtg caccacttca taagtagcat cagggatttg gagaaccttg accgatactg
    42241 gattttccac accagacagg ttgtcctgca ttccgtcacc gaccttactc aagataggac
    42301 cttgaacttc gacaacttct agcttatctt tcaaatactg ggtaaaagtg tttttgacaa
    42361 aggaaatttc ttcttgttga tggataaaac ttttcttcat agacaactcc tcaaaaattt
    42421 aataaacgta ttatacacct atttccaaga aaagaaaaga gaaaatttaa aaaaaaatca
    42481 gtgtcactca aaacactgat ttcatagacc ttttagtcat tgcgaccaaa gatacgtaga
    42541 atacttagga aaagattgat aaaatcaaga tagatgctga gagccattga caccacccag
    42601 cctgtcgcta cacgaccttg tgattgttca taggcgaggc gaatcttttg gttatcccaa
    42661 gcaatcaacc ctgaaaaaac caaaaccatg gctacgctaa tcatataatc aaagaagcca
    42721 ctagccaaga aaatattgac taccatagca atcagtaaac caatgagagc tgccatcatt
    42781 gctcgaccaa tcccactcaa gtctttcttg gtaaaaatac caactgccgc catgacaaag
    42841 aagagaaggg cgctcgatac aaaggcagat aaaactgtac ccggagtata gaaagccacc
    42901 acaaaactaa gggtaaagcc gtttaaaacg gagtaaagta aaaatactgg aagagcagct
    42961 ggactatttc ttgaagccat gctactggca acgaaaacca aagccaactc cgcaaaagta
    43021 gcaatggtca accagagacg cccctgcatc aaaaagtaaa ccaactgaga ctgaaagacc
    43081 gtcaacataa ggcctgatac caaagcagat agtccgattc ccagaccaac aaaggcataa
    43141 accttagcgt aaaattgatt gagacctgca cggtcatgta taatagtgtg attcatccat
    43201 ttctcctttt ctgtgaacat ctttccttga ttataacaaa aaaagttaaa attagcttaa
    43261 atggaagatt aaaataccgg ctgcaaccgc aacattcaaa ctctcggcct gccccttcat
    43321 gctaatatgg accaactggt ctgcactttc agccataagg ggactaattc cttgaccctc
    43381 atttcccata actagtacaa aattttctat agaaggcagt tctctgtaat caacagaatc
    43441 tttagatagg gttgttgcta gcactgggat agctaccttt ttagtttcgt caagaagcgc
    43501 ttgactagtc atccggtaaa tgggcagatg gaaatgacta ccttgcatgg aacgtagggt
    43561 tttgagactg tagatgtctg ccgacttatc tgaaacaatc actcctgtaa aacctgctgc
    43621 atccgcagtt cgaatgatag ttcctacatt accaggatct tgcacatctt ccaaaaacaa
    43681 gaacttgccc tgactcaaat cagcttgtcc tacttcttct ttttgaacca cggcaacaat
    43741 tccctgtgga gtctgagaat ccgccaaatc tagcaaaata tcctctgaca cccagacagt
    43801 ttgcgaaaaa gtagctaact gatctcgata attttctagg gcaaagattt tctcaatcgt
    43861 cactccagct tggacagctt cttcaaacaa gtgccagcct tcaatcaagt aggcagactt
    43921 gcggtatttt ttttggcgta atttcttggc attttttacc acagaattgg cttttgaggt
    43981 tataatagtc atagaaatat tataacacaa tcaaaggggt ttggtatgca aaaggttaga
    44041 atgattgccc aaggtagggt acagggagtc ggctttcgtt ggggtgttta cagcttggca
    44101 cttgaaattg gtggcatcac aggtcgagta tggaataacg acgatggcac agtggaaatc
    44161 ttagcccaag cagactcatc tgctatcatg gcaaaattta tccaagaaat ccgaaaagga
    44221 ccgacacctt tttcaaaagt aagctactta gatgtcaaac taagcaactt tcctccctac
    44281 tctgacttta aaatcgcaaa ttaggtctcc agaactattg tatattttgt aaaaaaacag
    44341 tagaatagaa aggtataatt tttaaagaag gaataaaaac agtgaaatct attaaacgtt
    44401 ttgcactctc agctatggga gcggctatgt tgcttgtctt gactggttgt gtcaatgtcg
    44461 ataaaaccac aggtcagcca acaggattta tttggaatac catcggagcc cctatggctg
    44521 aagctatcaa gtacttcgct actgataaag gtctaggctt tggtgtcgct atcatcatcg
    44581 taaccattat cgtgcgcttg attatcttgc cacttggtat ctaccaatca tggaaggcaa
    44641 cgcttcactc tgaaaagatg aacgccctca agcacgtcct tgagccacac caaacgcgtc
    44701 tcaaagaagc gactactcaa gaagaaaaac tcgaagccca acaagctctc tttgctgctc
    44761 aaaaagagca cggtatcagc atgtttggcg gtgtaggatg tttccctatc ctccttcaaa
    44821 tgcctttctt ctctgctatc tactttgctg cccaacatac tgaaggggtt gctcaagcaa
    44881 gctacctagg cattcctcta ggttctccaa gtatgatttt ggttgcctgt gctggtgtcc
    44941 tttactatct tcaatcgctc ctttcacttc acggagtaga agatgaaatg caaagagaac
    45001 aaatcaagaa aatgatttac atgagcccac tcatgatcgt cgtcttctcc ctcttctcac
    45061 cagctagtgt cacactttac tgggttgtcg gtggtttcat gatgattctc caacagttta
    45121 tcgtcaacta tatcgttcgt ccaaaacttc gcaaaaaagt ccgtgaagaa ctagccaaga
    45181 acccaccaaa agcaagtgct ttctctaaac caagtggacg aaaagacgtt acccctgaac
    45241 aaccaactgc tatcacaagc aagaaaaaac acaaaaatcg caacgctgga aaacaacgtt
    45301 cgagataaga agaaaaaggc ttagctgatt tgctaagtct ttttgcaaat caaaagcccg
    45361 atgtttccat caggcttctt ttctatccat gtacacgttt catataatct tgataacttt
    45421 cggtatccat gagtttttta gcgttcttga cgcgatctgc tgttggtggt ttgactcctt
    45481 cgagggaata tggaattcca agttcacgcc acttgaactc acccatggtg tgataaggta
    45541 gaatttcaaa cttatcaaca tttttgaggg tcttgacgaa cttaccaagt tcaatcaagt
    45601 catcatctct gtctgtcaat cctggaacta gcacgtggcg aatccagaca ggttttccaa
    45661 tatctgatag atactgggca caagccaaga tatttttatt ggtttgtcta gtgacaatct
    45721 tgtgctgttc ttcgttgatt tccttgatat ccaaaagaac caagtcagtg acagccatga
    45781 gtttgtcaaa cttctcaagg taacgtggtt tattacggaa aggaagagca caggtatcca
    45841 aggtacagtg gattccttgt tccttagcct tggtgaagag agcaatcagg aaatcaatct
    45901 gcaagagagc ttctcctcca ctgactgtaa tcccaccctt atttccccag aaaccacggt
    45961 agcgcaaggc ctctgtcaag acatcatcta ccgtccgttc acgtgactta ttggactcca
    46021 tagcccaagt gtctgggttg tggcaatact ggcaacgcat gtgacagccc tgcaaaaaga
    46081 caataaagcg aataccaggc ccatctactg acccaaagct ttctgtcgaa tgcaccattc
    46141 ctgtcacttg tccataatca attgtttctt cagacatatc gttaccttcc ttgaaaacgt
    46201 tttatagttt tattatatca cgacttgaag gaaaaacaag atttttgcct attttttaga
    46261 aagcaatctg tttttcaatt tcattttcaa tctattatca gattattctt caaaatcgaa
    46321 gccatataag gttgcaaaat agtcctcagg gcgctctgca cggcggattt gacgggcttt
    46381 accttcttcg gtatagagga tttccgcaga acgtaatttg gcattatact ggtagcccat
    46441 tgaaaatccg tgggcacctg tatcatgaat taccagcaaa tcaccgattt ctgtatgagg
    46501 cagttcgcga ttgactgcaa atttatcatt gttttcacag agtgaaccaa ccacatctac
    46561 cgcttcagct ggtccatctg gatgggtcac gttgctaata tgatggtaag ctccgtacat
    46621 agctggacgc atgaggttga ctgctgaggc atccacacct agataggtac ggtaggtttc
    46681 cttcttatga gtcactcttg tgactagagc accgtgaggt gccagcataa aacgacccaa
    46741 ttcggtgaaa atcttgacct gaccaagacc tgctgacgta agaacttctt catacacctt
    46801 acgaactccc tcaccaatca aggcgatatc gttcggctcc tggtctggac gataattaac
    46861 accaataccg ccagaaagat tgataaagtc tagccaaatg cccaactttt ccttgatttc
    46921 aacagccagt tcaaagagct gacgagccaa ctctggataa tagagatggg tcacggtatt
    46981 ggacgctagg aaggagtgaa tcccaaaagt cttggctcct ttttccttca agatagcaaa
    47041 ggcttcaaag agctggtcct tggtcatgcc aaacttagcc tccccaggat tgtccataat
    47101 gtctgtcccc agttcaaaaa cgcctccagg attataacga caagagatga tttctggaat
    47161 gcctgctact ctctccagat gttcaatatc ttcaaaggca tccaagttaa tggtcgcacc
    47221 caattcacgt gcataggcgt attccttgtc tggcgtgttg ttggaagaga acataatctc
    47281 agaacccaga aagtccagtt tatggctcat caaaagctct acataactag agcagtccac
    47341 accacaacct tcttcttgga gaattttcaa aatagctgga gttggagtag ccttaactgc
    47401 aaaatattcc ttaaagccct tgttccacga aaaagcttgg ttgacggctc ttgccttctc
    47461 acgaatcccc ttctcatcat acaagtgaaa gggagtcggg aactcggcaa caatcgcttc
    47521 taactcttct ctattgataa atggtgtttt cataagcttc cttctattct gtttgcaaag
    47581 aaaggctggg acaatcgttc caacctttag ttctatctct tatttatctt cgtcaaagat
    47641 attgccaacc tcaacatcga tggcttggtt cttgacatca atattagtta ccttcaagag
    47701 tgacttgtag tcaaactgct tttcacgttc ttcttgggca ttgtccgcaa agaccgctac
    47761 acctgccagt tctgagtcga actcgcgcaa gagactaatc ataccgttga ccgttccgcc
    47821 acctttcaag aagtcatcca caatcaagac acggctacct gccttaagac tacgttttga
    47881 aaggaacatt ttctcgatac ggtcaccact tgaacctgaa acatagttga cgctaacagt
    47941 tgaaccttcg gtaattttca ggtcacggcg cacaatgaca aaagagacat tgaggacatt
    48001 ggcaactgca tttgcaagtg gcacaccctt agttgctacg gtcataaccg cgtcaatttt
    48061 ttggtccata aagcttttgg caataatacg accaatattt ttcaagatgg ctggtgtgct
    48121 aagcaaatca gacagataga tataaccacc tggcaagata cggtcacttt ctgacaactt
    48181 ggtacgcaag tcttcaacca tttccttagc atcctgactc gaaatagacg gtgtgaagat
    48241 gacacctccg ccagccccag tcactgtctg gatatgaccg atttcaattt cctcaaaggc
    48301 gcgtttgata atgacgatat cttctgagat ggatgattta gcagactcat acttttcagc
    48361 aaaagtattg agactagtta gtttataagg attattaatc aaatagttgg aaatgacaac
    48421 catccgatca cttcttctta atttcatttc tatttcctat tccattttta ttcaaaaaat
    48481 caaaaagcaa actagaaagc tggtcgctgg tggttcaaaa cactgttttg agattgtcaa
    48541 tagaactgac aaaccctgta atatacctgc atatatacat acgacaaggc gatactaccc
    48601 tagtttgaag agattttcga agagtattca tttttgtctt ttacttatta taccatattc
    48661 acataaaaaa acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttattaatct
    48721 aaatctggtt tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct
    48781 ttatccacca aagcaagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc
    48841 atatggataa tctctgcttc cataatgcgt ggacggactg ggcttccata ctcaagcaag
    48901 ccgtggtgac tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg
    48961 ccgagttcca taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga
    49021 ttacctcgca ctgtgtactc tgtctggtct ggccccgtca actcgatgac cttagctaag
    49081 tcatgcaaca taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta
    49141 atagcgtctg ccaaacgcac catggtcgcc gtatgatagg ccaagcccgt ttcaaaggca
    49201 tggtggttgg tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga
    49261 tttcggacaa tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag
    49321 tcacgaattt ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt
    49381 tcaccagctt gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact
    49441 tctcggcgtc ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt
    49501 tgggcatccc agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg
    49561 tagtttttcc cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca
    49621 aatagctcat cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg
    49681 gagtagatca agcgcaggct cgccttctga caactcaatg tgacggagcg tccgctcgat
    49741 agctatggta cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt
    49801 ttgtgccttg accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt
    49861 cttgctgata tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgataggga
    49921 gttaagaagg gctgataggg tacttggtcc tgcaacgata atctgttctt cccgtctcaa
    49981 atcatcaaag aagaccggat tgcgcacaat ctctgaataa agaccttctg tcggaacaaa
    50041 caaaactcca aaattggtcg tccgaggcgg tgctatgtac ttgctcttga tatccttggc
    50101 aaagcgcttg acgcttgcta ggagtgactt acgacagcgt tcaatctcat ccttgtcacc
    50161 tgtctcatag gcttcttcca agcggtaata atctgccagt ggaaacttag agtcaattgg
    50221 cagatagacg tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc
    50281 actagagttt tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc
    50341 aataatttgc cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac
    50401 cttgttaaga gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac
    50461 agactccagt tgtttagaaa ctgtctcaaa ggaagcctgt aagcgtgtct gcaaggtctt
    50521 ttctagtttt tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg
    50581 caaggcttgg agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc
    50641 ttgacggact tgggtcagac cttggtgcaa ttcaatccgc acttcttgca aacggtcgct
    50701 gacaaccact tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg
    50761 gtaatccaac tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt
    50821 ctcctgccta tcctgccttt gccaaatcag aaagagacca gctaggttgg caattaataa
    50881 tagaataagt aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac
    50941 catctgggca agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt
    51001 taaagaaaaa attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat
    51061 cccgaactgg cataaaggct agatagtcgt agtctgaacg aggttctagc tgactggtcc
    51121 cttctggaca ataagtaatc aagttttgcc catcctcaat ttctatttga tgcatatagg
    51181 gtgccaactt aggattgcta ggcagaaaga cattggccaa catatggtca atacggccac
    51241 ccaaggcacc gaaaatagta acctgagcct gaggattttt ctcaaagatg gttaagagag
    51301 ccaattccaa atcggtatca tctttttctg gtcgggcttg gacaaaatgc tgggcacgtt
    51361 tttgaatcac ctgtcgctct tcttcggtca cagaatcaaa atccccaact gctagagcaa
    51421 gaagcaagtc ttcttccaag acccagagcg agcctcgatc caccccaaca aaagcatcaa
    51481 aatctgtccg ataatgaccg cggtctccgc ctgcaaaaac ggcaacccta gtccagttgt
    51541 tttctgagag tttgtactcg ctcattgaca tctcccttaa agacatagga acctgctaca
    51601 aaaacggtcg caccagcttc tttggcttgg gcaatagttt ggtcatcaat cccaccatcc
    51661 acttcgattt caaagttcaa acctttttcc tcacgaagag caaccaactc acgaacctta
    51721 tccatggttt ctggcagaaa ggcttgccca ccaaaacctg gattaaccgt catgactaaa
    51781 acttggtcaa ctagatgaag gacgtgcttg atggcttcaa ctgatgtgcc aggattgata
    51841 acgactgaag gcttaactcc gagtgaacga attttttgga gggcgccatg aatatgaggc
    51901 gttgcttcta catggatact gatgatgtct gcacctgcac gcgcaaaatc ttccagatga
    51961 tgctcagggt ttgacaccat caagtggcaa tcgaaaacca tcttactatg aggacgaagg
    52021 ctctcgacca cacctgcacc aaaactgatt tgcggtacaa aatgactgtc catgatatcg
    52081 atatgggcat attctgcccc agttgcttct agacgtttga tttcacgttc aaagttggca
    52141 taatctgctg ccagaattga cggagcaatc ttgtattgag acataggttt ctccttattt
    52201 tggaattttt ttgctgactt ttttataggt ttctctacga ttttcaattt cactaaggaa
    52261 ttgcaggtaa ttgtcaaaac ggaaggttgc aataacaccc tcttcaacag ctggtttgac
    52321 ggcacaagac ggctcatggg tatgggtaca agtacggaac ttacaatctc ggctaacagt
    52381 agcaatctct ggaaaggcct gattgaggtc ttcagccctt gatacttcat agtccagaga
    52441 tgaaaagcct ggtgtatctg cgattttacc cccgttgaga ttgtaaaaac taacagctcg
    52501 agtggtatgg cgaccgcgac ctagactgtc tgaaatttct cccgtttcaa gattgaggtc
    52561 tggtgcgatt ttattgagaa gagttgactt cccaacacct gtctgcccca taaagaccgt
    52621 aaccttgcct gttaacaaag acaggagttc ctctttactg gtcacaaagt catagccgat
    52681 gtcaccatag gtctgctggt aaaaatccag ttctccccta tcttccaaca aatccatttt
    52741 ggaaatatag acaatgggat ggatgccctt gtgctccaaa agaaccaaga aacgatccag
    52801 caaattgctg ttaaaatcag gttccttgac ggacatgatt actacagctt gatcgatatt
    52861 gacaataggc ggacgaacca gactgttttt ccgttcgtga attttgagga tatagccttc
    52921 tgaattttcc tcggcagaga aatctaccca gtccccaaca taaggggtat ggcctttttt
    52981 acggaaattc ccacgcgcgc gtgtttgata aacctggcca tcactctcca catagtagaa
    53041 acctgccaag gctttaatga tttgtccctg catcttagag tccttgccct ttaagtgcgt
    53101 ctgctagacc ggcaaattct gccaagctga gagcttcccc acgcacactt ggtgacaagc
    53161 ctgcctggtc caaagccttg gtcagcttgt ccttgacctc ttcagtctta ccaaagtaac
    53221 ctgtcaagtt attccacaag gtcttgcggc gatgggtaaa actagccttg gaaaccttaa
    53281 agaaaaagtt ctcatcttct actgctacgg ctggctctgg acgacgcacc attttcaaga
    53341 tggctgaatc cacatttggc gctggcacaa agaccgtacg aggcacgata aaggcaacct
    53401 tggctgtcat gtaatactgc acggcgatag acaagctacc gtaagccttg gtgttaggct
    53461 gggctgaaat gcggtccgct acttctttct gcatcatgac cacaaactca caaaaaggaa
    53521 tgccactctc aatcaagtgc atgagaatag gcgtcgtgat gtagtaaggc aaattagcca
    53581 ctaccttgat tggcaggtta ggatttttaa aattttggat atgttgcgcc aaatcaacct
    53641 tgagaatatc ttcgttaact acggtcacat tatcaaaatc acgcagagta tctgccaaaa
    53701 ttggcatcaa acggtggtca atctcaaaag ccatgacttg ggctgcacgc tcagccaaaa
    53761 attctgtcaa ggcaccaata cctggcccga tttcgatgac attgacctga tcatcaattt
    53821 cagccgtatc cacaattttt tgaaggatat tggtatccgt caagaaattt tgcccaaagg
    53881 actttttaaa ggtaaaaccg tgacgctcca acactgcctt ggtcacgcta taatctgcaa
    53941 ttctcatcta ttctcttttc tattatctgt tactactatt gtaacacatt ccccttgtat
    54001 tttgggaatg aaaatcatac caaaaaacta tctttcctca tgaagaaaga tagtcttgga
    54061 aatctttaaa gagggactta gtgcttctct cgaaacatac gttcatactc ttcgaaaatc
    54121 tcttcaaacc acgtcagctt caccttgccg tactcaagta cagcctgcgg ctagcttcct
    54181 agtttgctct ttgattttca ttgagtatca aaaaaatcag cttcttgata acttcgattt
    54241 tcgggtaggg tcaaatccac atcctcctcc acatcatcca ctgtcagttc aaccgtctga
    54301 ggtaaatttt tcaaacgata atgcttttgc ctttgccctt caatactagc aaaatcaagc
    54361 aaatagccat gcactcggat ttgaaccaaa aggagatgat tggtcatatt ttccatgatg
    54421 aggatatctt ctaaaccacc tctggcacta ggataatcag ataccctgcg aatacggatt
    54481 ttttcacaca tgagcaagtt tcctcatatc aatgatttca tcagccttat tccagactag
    54541 gggattatgg gtcgcaatga tgataattcg attttcatct ttcaaatcca ccaagagatt
    54601 cataacctcc tctgaatttt caggatcaag agctgctgtt ggttcatctg ccaaaatcaa
    54661 gggtggattt ttcaaaatag tcttagcaag ggcaactcgt tgggcctctc ccccagataa
    54721 agtataaatt ttttgttcta aatccaaata ccctagatta actttttcta aagcccccac
    54781 ttgcctttcc aaacgttcta cttttgagat tttctgacca acaaaaccca aatccaaatt
    54841 ttctttgatt gattggtttt ctaagaggcc gaaattttga aagagatagc ccatctggtc
    54901 tcgaaaatac tcacgagtag gaatggtttt taaatctttc ccctgataga gaacccttcc
    54961 accatctatc ttttctagct ttcccaagat attcagcagc gtcgtctttc cgcttccact
    55021 ctttccgatt aaggcataaa ccttgccctt ctccagcttg agattcaaac cagagaaaat
    55081 cgcgcggtca ttaaatttct tttccaatcc ttgaatatca atcatcttat tttcctttca
    55141 atactgccat gctaccagct tcttcttttt tatcctgcct tactaaaatc aagagggcgt
    55201 taagcgtaaa caaagctaca actagagcgc taatcaaacc atctcttgtc aaaatactag
    55261 ataggactag gccaagcaag agaactcctc cttgcgccag taaatacttg ccatgaagct
    55321 catagattgt cataccagca agacgtttaa tcataagttc ccgtctgaac tgctcaaaat
    55381 agagaagatt catggaatca aataacaaga tagccgtaga cagggtcaaa atcgtcccaa
    55441 taaggagaga gtaaaactcc acccgtttgt catttagtac cttggcaaaa aatagctggc
    55501 tttttaccaa gtaagaaacc ttgtgataca gaccttgctc ttttagagct gtgatgctgt
    55561 ctccatatcg atctagtttc aaggcactat tagccgtagt tccccacaac atccctgcaa
    55621 caggtcttgt tccagtcgct tgcggcgtta gaactacaat aatcggatct tttaggtact
    55681 ggcgtgttgt cttgtaccca tcattataga ggaaacgttc ctgtcctgtt tctgtaaaag
    55741 ctagccttac ctgtgggagg tagtgtttct gactcgtcac ttctacactt tcagatgaaa
    55801 agttttgcag gtaatctgta aacaatcctt ggtagtaggc agactgctct cgcaagctct
    55861 caggcaagat cagcccaaac tctccctcag acaagttttg catcttgtcc ataaactctg
    55921 aagaaacggt aatcttttct tctatcagat agcgcggcga gacatagata acattcccta
    55981 acggtgtgta gtcactgaga cgattgccat ctaggtccac ttctgctcca tctgagaaat
    56041 tgtcaacatt gctcataata taaaaagagt ctgtattggc taaccgttct tcagtaaatg
    56101 tctgccactc acgattatcc ttacgcgttc cttcttcatc ggcaaatgca ctagaccaac
    56161 caaaggatag acggtaacgg tctgaggact ggctccattt attgctagct ctctccattt
    56221 cctgcatttc acggtagtgg ggtaggagag ctgtcgcact cgatccgacc accaatacag
    56281 ctaagagttg ccccaccatc atcaatgtca tcatacgttt gagagggagt ttccctttca
    56341 atagatccac cagactattt tcctgtaaac caagtagata gacgacactt agtaaggtag
    56401 aaatccctgc caaggtcaat ccataaagta gaagagcaat gatgaccagt tgtaccgttg
    56461 ccataaacaa ggcaccttga taccagagaa tccccaatcc caaaagactg gataccagca
    56521 ctgagcagat aagctgtctc acatcttcta acactggtct gagagcaact ccaaacaagc
    56581 tctcaccagc tattaagcga atccctgcct gacgaaggga tttgatccga taaatcaggg
    56641 tcagactcat aaaggtcagc agaaaaatag ctaaactcag tagcaccata ggggtggccg
    56701 ccaatagtaa gactatcgaa aatggatctt ctccattcga aacaaagcct tgataaccaa
    56761 gctctttcaa ggtggtctgt aagctcactc catccaaact tcctgacaca atcaagtaag
    56821 accctaataa atcactcgtt tctgcactct ccttggagga aatggtcaga ccttctggaa
    56881 gctctccctc accataagtg gcataggtaa agagtgtttc tccagcttca tttggctcaa
    56941 cgattcgacg ggcgatgaga ctattatgct ctaccgccaa gtgactcaaa gcctctgtca
    57001 cctcttcgcg actagctact ggttgattta tcatcattcc tgtcacatca acagaaggat
    57061 agttaccaaa taaaatctct tctcgatggt caacggaagt tatcaccata taaagcgata
    57121 ccaataccat tgaaatcaaa ataaataaac gtttcatcat ttcctccaaa aagttacttg
    57181 gtcacttagt gagaaggtga ccaagtaaag ctaaacaata gggctatacc attctaaaca
    57241 ttatagtaga atgcaacttt ctctccccaa gaagtacgaa tccatgcacg agaagtccct
    57301 ccagcaccag catatccctt gtcagatgaa ccagtttttc tgctaacaac tgttgaacta
    57361 tggtattttg aagggtgata gtagtttgag taagcaccac cgttacctga accataagtc
    57421 caaacaccac cttctgggta ttgaacggct gcagaggcaa ctgatacacc tccacctaat
    57481 gttgctgcaa tgctcgctac aagagctaac tttttaactg tttgtttcat attgatactc
    57541 ctctattttt gattacaaga ttgttgagtt acttgctcct ctttccatta tcaacgttga
    57601 tactattata ttaccaaatg atattctaaa attatttgtt tttctctaaa ttgtcaaaat
    57661 agcaccctga aatgaacttt tatagtcatt atactccatc tttatcacac tatcaaggac
    57721 atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct aaaaaaacag
    57781 ttctaaagac gaactttaga actgttttga tacgaggaca aggacatttt tgtcactgat
    57841 tcactatgtt tataaatatt ttttgacatc ctcttgccat tcctctgtca atttctttac
    57901 tagaaatcca tctccaatta gcttcgcaaa tgttttagaa gactgataaa atgattcagc
    57961 taaactaaaa tctctttcta ctcttaatgc ttgcttccac aaaaacataa atacaagagg
    58021 tttcttttga taatcttgag ttttatccat aatttcttgt aaacacgata gataatcatt
    58081 aaaacaatca gttactccta ccttttcaag acaacacatt cctgaaataa gagtatctct
    58141 aattataaag aagttttcta atttagttac ctttttctgt tccaaaagaa agagcattag
    58201 cttttcgatt tgatttataa atttggcaag atcttttcta atgagcattt gataaaaaaa
    58261 caaacgaatc aacaacatat catttgttga ataaacttct ttttctatga tctgagacat
    58321 atgttcctca agtattaact ctgcatattc aggccttcta gttctagaag tatccaaaca
    58381 cgcctgcaat acttcacatg ctaattgttc ttctttagga agattatcaa agtatgtttt
    58441 ataaatctct tccaaacacg cttctttctt atcatactcc tcttctttac catagattgg
    58501 ttcacgtaaa atctggtatt tcaattctaa ataagcagaa ggaagagctg aaaaatccgg
    58561 cataaggcta taaactggaa ctcctagccg gcgagcaata taggctaact tgggcaaact
    58621 cggttgcgaa gctccacttt caattcgcga cagttgacga actgtcagtt cttgctcatc
    58681 tccacaaaaa tctggacgac taattccttt ttctatccga atctctttaa ttttttgacc
    58741 aattaacatc agacgcctcc tcttctacct gcttcgaaaa atactgtgaa acttaaaaaa
    58801 ttgtaacggc tacatctttc ctactcataa gatttcatag cttcttccac ttctgccaaa
    58861 gtaaccccaa acaactctag gcgtttgagg agttgcttgc cattagaata gccgattcgg
    58921 agagtctctc cgagatattc tctacgctta cggctgtctg cccctgctag aaaaccaagg
    58981 cgaatcaagt cgctacgact aatgtcaaac tgactctcat gttcaaattg ttctgtcacc
    59041 tgagctagag ccgttttcag gtcttcatag ctggcatgct caattcccag agaacgcccc
    59101 ttggtcttgg acttgggaac agcttcatct cgcttgagaa aggcatgctg aactgttgga
    59161 atggccgtca taatcatgcg ccgaatccgc tccccattaa aatctgggtc tgtaaagaca
    59221 atgactccat gacgttggtg tagacgctga attcgctcta tatcctgatc attgatggca
    59281 gaacctcgtg tctcataggt ctccacatcg aaataacgct tgagattgac cgtatcatag
    59341 cgaccttcaa ccacgataac ttgagaaatt ttctctttca ttacttgctg tccaatccaa
    59401 aaattcgttc tgcatttgca gtcgttgcta ccgccagctc ttctgtcgtc ataccacgca
    59461 agtcagcgat aaagtcgacc acatagcgag tataggctgt tttattttca cgaccacgct
    59521 tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa catcttgtcc aaaggtaact
    59581 ctttagctgc ttcttggagg tcagttgcct tcttgaaagt caccactcct gagaaggaaa
    59641 tggtcatacc aagatccaca aacttctctg cccactcaag cgtccctgaa aatgaatgca
    59701 tgataccacc acgaggacca acgccctcac tcttgataat ctcataggta tcttccagcg
    59761 catcacgggt atggacaaca aaaggcaaat ccaagtcctt agatagctga atctgacggc
    59821 gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca atggtagtct aagccaattt
    59881 cacctaaagc cacaaccttg gaatgtttta acttatccaa caagtaagcc tcaacttcct
    59941 ctgtataagt accagcttct gtaggatgcc aaccaatagt cgcatagagc tgctcatact
    60001 catctaccaa ctccaaggca cgctcaatcg tcggtttatc aaaaccaaca atattcatct
    60061 gtatcacacc catctcagca gccaaggcaa tttcttctgc ctcacgacct gcaaattctt
    60121 ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc taacctcgtt ttctatcttc
    60181 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
    60241 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
    60301 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
    60361 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
    60421 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
    60481 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
    60541 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
    60601 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
    60661 actggtctct taggaactgt aaccatggca atggcttgca ctccaatcgt ttctgcttcc
    60721 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
    60781 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
    60841 tcctgcttat ccttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
    60901 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
    60961 gcctggctac caccgccttc attcgcatta gcatctgagc ttccagtatt gcctccctta
    61021 tctccacctg gtatagtttc tagcttatac tctagtgtag cttcttgagt tacagattca
    61081 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
    61141 aatgtgattg ttgctgtacc atctccagct acattgattg tcgctccgtc taatgctgaa
    61201 ccatttgctt gtaaaatagc aaccttaact ttttcttcat ctgttaaatg agttatatct
    61261 tttacatcta ctctttgagc aggtgcttta acagttgatt tttcagcagt cggtttagtg
    61321 ctatcttgtg cttttggatc ttgtgctacc aattgatttc ctggaattgt aatagctgaa
    61381 ccatctttaa agacgattgt tgctgtacca tctccaccta cttcaacttt atagtaaaat
    61441 aaaataataa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    61501 aacagaggtg tactattcta gtttcaatct actataacat cgcttccgaa tccatttgca
    61561 tctactgaac ttttttacaa aaataaaaat cagtagactc gagttcctac tgatttttga
    61621 tagaattcgt ttggattatg cagccaaaac tttgcgtcct ttacgacgac gagctgccaa
    61681 tacgcgacga ccatttttag ttgacatacg gttacggaat ccgtgtttac gcgcacgacg
    61741 aagtttactt ggttgataag tacgtttcac gatgaatacc tcctcataga ttttgtattc
    61801 gtttagccgg ctataaagtg atcagttact aaacatactt tactattcta tctgattctt
    61861 tcacttttgt caatagctct aggcaaatgt ttccagcttt ttcgaatgca agccct
//
LOCUS       DBEJJV010000008        59203 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.008, whole genome shotgun sequence.
ACCESSION   DBEJJV010000008 DBEJJV010000000
VERSION     DBEJJV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 59203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59203
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.008"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(83..1084)
                     /locus_tag="ACL3GT_000560"
                     /pseudo
     CDS             complement(83..1084)
                     /locus_tag="ACL3GT_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            1380..1685
                     /locus_tag="ACL3GT_000561"
                     /pseudo
     CDS             1380..1685
                     /locus_tag="ACL3GT_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884744.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            1817..2761
                     /gene="manA"
                     /locus_tag="ACL3GT_000562"
     CDS             1817..2761
                     /gene="manA"
                     /locus_tag="ACL3GT_000562"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HGR0516269.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(2783..4258)
                     /locus_tag="ACL3GT_000563"
     CDS             complement(2783..4258)
                     /locus_tag="ACL3GT_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HGR0516270.1"
                     /translation="MVFLTDLRKHNRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSVIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALGAQAAFILLNIFIVSRGVQKGIERASKVMMPL
                     LFIIFVVIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMNFLVPNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSWSSSPNLCNQKGLE"
     gene            4341..5095
                     /locus_tag="ACL3GT_000564"
                     /pseudo
     CDS             4341..5095
                     /locus_tag="ACL3GT_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(5115..5570)
                     /locus_tag="ACL3GT_000565"
     CDS             complement(5115..5570)
                     /locus_tag="ACL3GT_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0516271.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(5590..6765)
                     /locus_tag="ACL3GT_000566"
     CDS             complement(5590..6765)
                     /locus_tag="ACL3GT_000566"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0516272.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFTGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(6824..7669)
                     /locus_tag="ACL3GT_000567"
     CDS             complement(6824..7669)
                     /locus_tag="ACL3GT_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0516273.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            7794..8351
                     /locus_tag="ACL3GT_000568"
     CDS             7794..8351
                     /locus_tag="ACL3GT_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0516274.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            8370..8837
                     /locus_tag="ACL3GT_000569"
     CDS             8370..8837
                     /locus_tag="ACL3GT_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HGR0516275.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            8926..9555
                     /gene="upp"
                     /locus_tag="ACL3GT_000570"
     CDS             8926..9555
                     /gene="upp"
                     /locus_tag="ACL3GT_000570"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HGR0516276.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            9729..10319
                     /gene="clpP"
                     /locus_tag="ACL3GT_000571"
     CDS             9729..10319
                     /gene="clpP"
                     /locus_tag="ACL3GT_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HGR0516277.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            10398..10646
                     /locus_tag="ACL3GT_000572"
     CDS             10398..10646
                     /locus_tag="ACL3GT_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HGR0516278.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            10747..11907
                     /locus_tag="ACL3GT_000573"
     CDS             10747..11907
                     /locus_tag="ACL3GT_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0516279.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            12175..13044
                     /locus_tag="ACL3GT_000574"
     CDS             12175..13044
                     /locus_tag="ACL3GT_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0516280.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            13048..14004
                     /locus_tag="ACL3GT_000575"
     CDS             13048..14004
                     /locus_tag="ACL3GT_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HGR0516281.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            14004..14768
                     /locus_tag="ACL3GT_000576"
     CDS             14004..14768
                     /locus_tag="ACL3GT_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516282.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            14768..15478
                     /locus_tag="ACL3GT_000577"
     CDS             14768..15478
                     /locus_tag="ACL3GT_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516283.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            15892..16548
                     /locus_tag="ACL3GT_000578"
     CDS             15892..16548
                     /locus_tag="ACL3GT_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HGR0516284.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            16656..17751
                     /gene="prfB"
                     /locus_tag="ACL3GT_000579"
     CDS             join(16656..16727,16729..17751)
                     /gene="prfB"
                     /locus_tag="ACL3GT_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HGR0516285.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            17769..18461
                     /gene="ftsE"
                     /locus_tag="ACL3GT_000580"
     CDS             17769..18461
                     /gene="ftsE"
                     /locus_tag="ACL3GT_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HGR0516286.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            18454..19380
                     /gene="ftsX"
                     /locus_tag="ACL3GT_000581"
     CDS             18454..19380
                     /gene="ftsX"
                     /locus_tag="ACL3GT_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HGR0516287.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKV"
     gene            19666..21846
                     /locus_tag="ACL3GT_000582"
     CDS             19666..21846
                     /locus_tag="ACL3GT_000582"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HGR0516288.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            21898..22713
                     /locus_tag="ACL3GT_000583"
     CDS             21898..22713
                     /locus_tag="ACL3GT_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0516289.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            22853..24196
                     /locus_tag="ACL3GT_000584"
     CDS             22853..24196
                     /locus_tag="ACL3GT_000584"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0516290.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            24412..25602
                     /gene="metK"
                     /locus_tag="ACL3GT_000585"
     CDS             24412..25602
                     /gene="metK"
                     /locus_tag="ACL3GT_000585"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HGR0516291.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSEEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIKK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            26155..27090
                     /locus_tag="ACL3GT_000586"
     CDS             26155..27090
                     /locus_tag="ACL3GT_000586"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HGR0516292.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            27124..28161
                     /gene="holA"
                     /locus_tag="ACL3GT_000587"
     CDS             27124..28161
                     /gene="holA"
                     /locus_tag="ACL3GT_000587"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR0516293.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            28334..28939
                     /gene="sodA"
                     /locus_tag="ACL3GT_000588"
     CDS             28334..28939
                     /gene="sodA"
                     /locus_tag="ACL3GT_000588"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase SodA"
                     /protein_id="HGR0516294.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELTAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            29096..29626
                     /locus_tag="ACL3GT_000589"
     CDS             29096..29626
                     /locus_tag="ACL3GT_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HGR0516295.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            29647..30549
                     /gene="rlmN"
                     /locus_tag="ACL3GT_000590"
     CDS             29647..30549
                     /gene="rlmN"
                     /locus_tag="ACL3GT_000590"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0002935 - tRNA
                     (adenine(37)-C2)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0070040 - rRNA
                     (adenine(2503)-C2-)-methyltransferase activity [Evidence
                     IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HGR0516296.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVSCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFADEGVQVNLAVSLHA
                     PNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAE
                     LLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDID
                     AACGQLRFNTMKRDRQKAVAAVNP"
     gene            30549..31031
                     /locus_tag="ACL3GT_000591"
     CDS             30549..31031
                     /locus_tag="ACL3GT_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0516297.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQPL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            31033..32574
                     /locus_tag="ACL3GT_000592"
     CDS             31033..32574
                     /locus_tag="ACL3GT_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0516298.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(32630..33433)
                     /locus_tag="ACL3GT_000593"
     CDS             complement(32630..33433)
                     /locus_tag="ACL3GT_000593"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HGR0516299.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(33517..33730)
                     /locus_tag="ACL3GT_000594"
                     /pseudo
     CDS             complement(33517..33730)
                     /locus_tag="ACL3GT_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(34209..34418)
                     /locus_tag="ACL3GT_000595"
     CDS             complement(34209..34418)
                     /locus_tag="ACL3GT_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516300.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            34588..34860
                     /gene="rpsP"
                     /locus_tag="ACL3GT_000596"
     CDS             34588..34860
                     /gene="rpsP"
                     /locus_tag="ACL3GT_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HGR0516301.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            34880..35119
                     /gene="kphA"
                     /locus_tag="ACL3GT_000597"
     CDS             34880..35119
                     /gene="kphA"
                     /locus_tag="ACL3GT_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein KphA"
                     /protein_id="HGR0516302.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            35307..35592
                     /locus_tag="ACL3GT_000598"
                     /pseudo
     CDS             35307..35592
                     /locus_tag="ACL3GT_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654120.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG nucleotide pyrophosphohydrolase
                     domain-containing protein"
     gene            35696..36484
                     /locus_tag="ACL3GT_000599"
     CDS             35696..36484
                     /locus_tag="ACL3GT_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0516303.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPKMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            36515..37033
                     /gene="rimM"
                     /locus_tag="ACL3GT_000600"
     CDS             36515..37033
                     /gene="rimM"
                     /locus_tag="ACL3GT_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HGR0516304.1"
                     /translation="MNYFNIGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            37023..37742
                     /gene="trmD"
                     /locus_tag="ACL3GT_000601"
     CDS             37023..37742
                     /gene="trmD"
                     /locus_tag="ACL3GT_000601"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HGR0516305.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDDPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            37754..38092
                     /locus_tag="ACL3GT_000602"
     CDS             37754..38092
                     /locus_tag="ACL3GT_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP cone domain-containing protein"
                     /protein_id="HGR0516306.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(38123..38443)
                     /locus_tag="ACL3GT_000603"
     CDS             complement(38123..38443)
                     /locus_tag="ACL3GT_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516307.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            38541..38756
                     /locus_tag="ACL3GT_000604"
     CDS             38541..38756
                     /locus_tag="ACL3GT_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HGR0516308.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(38753..38899)
                     /locus_tag="ACL3GT_000605"
     CDS             complement(38753..38899)
                     /locus_tag="ACL3GT_000605"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516309.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKAKLMRFEEI
                     FEEY"
     gene            complement(38962..39498)
                     /locus_tag="ACL3GT_000606"
     CDS             complement(38962..39498)
                     /locus_tag="ACL3GT_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HGR0516310.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            39924..40262
                     /locus_tag="ACL3GT_000607"
     CDS             39924..40262
                     /locus_tag="ACL3GT_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516311.1"
                     /translation="MKKRINKKASVFLVASVFSFSFATTASVVNAVTAHPAPSPIIDV
                     WEYGVNDNYGYSNYFVSSPSNIGSKSSVTNFWGTVKAQDKKDYGWAYSSATKSWNDVR
                     LNAYWDYYRF"
     gene            40328..42310
                     /locus_tag="ACL3GT_000608"
     CDS             40328..42310
                     /locus_tag="ACL3GT_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516312.1"
                     /translation="MKLKLCIIGFFFCLIATIGLVTISDTEIPIPLPIDGAFSIQGKS
                     NLSNNEIYEMVRDLSKTEKVTIYKPIVQSSGQLKYVNFDDVNNEQLKSAPIVGMYYTL
                     GKMDVDSLKPLTMTGLQTVYMAYPWYIGGILQFTGTLRILLMGSIYLTLLVVLFVVRT
                     RQIKEGVIRRSLGLPIYDLRREYGISLIFELIMMALLMISYSSFLGNGFFTYSSKLFF
                     SLLLTNFILFQIIDLITFVLFWLTIQIEKPIEIIKNKAKNKLIFVVWLAIISIIILVS
                     GVFLQETKSSQSSINIQIQNLVPWDTVKDWRRIEFLGIESNSTKNREVNDSDGQYLQI
                     VAALKNLDFLYIERSSAYVPDFMKTSHVIENFSKQLENDGITNPEINKELIYINQTGA
                     NLQNKVNGTNYHLLDNKIATIYIPEKWKENQKSIENTVVAEQFIGTNYTREQLAVQII
                     PDGEKIFYFNEDADNNLKMKDILPLANVADSKDNIVVVLDTDKMMENNKFSLASNILY
                     KSLFSPEAVKKINEMTVLLNFSMNPVDVYQIVKLKIQSLEHQILLSQILQKIIYSIVF
                     ILIYQYVQLFITLKQNEYVKKIILGLSKTYIAISSLKYFMMTITMVILFTFLMTGQIE
                     LLYIGAASLLVLMLSIIMSFRKLSESYTKILKGDES"
     gene            42307..42930
                     /locus_tag="ACL3GT_000609"
     CDS             42307..42930
                     /locus_tag="ACL3GT_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0516313.1"
                     /translation="MTIDLLNVSKSFGSKKIFTDLNLIFESGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGNVLVDKQDIWKIKERTFFKNTVGYVFQNYSLIDNKTVYDNLSLIT
                     KDKKTITDVLEKVGLSSDYLHQKIYELSGGQAQRVAIARMLMKPRKIILADEPTGALD
                     GEIGKEIIRLLLNETAEDKYVIIATHDPAVYNEVDVIIDMKDIGYKV"
     gene            42927..43427
                     /locus_tag="ACL3GT_000610"
     CDS             42927..43427
                     /locus_tag="ACL3GT_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516314.1"
                     /translation="MKKKIYIALIFVTGVLAIFFFGKQMITKENINKPTVELTIYTLS
                     SSDTEKWNKVRQVETEEAIYFITVKEVSSSEEVFSNIIANGAATGFGVREEEVKKFNN
                     GLGDTIEDSKHNKLIEIEFFTFSDDGAGFVVANFDYGKEELNSQKKDIKELYKKIYES
                     FKEKNK"
     gene            complement(43593..44939)
                     /gene="gor"
                     /locus_tag="ACL3GT_000611"
     CDS             complement(43593..44939)
                     /gene="gor"
                     /locus_tag="ACL3GT_000611"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HGR0516315.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            45204..46403
                     /locus_tag="ACL3GT_000612"
     CDS             45204..46403
                     /locus_tag="ACL3GT_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_function: GO:0042802 - identical protein binding
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HGR0516316.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            46387..47088
                     /locus_tag="ACL3GT_000613"
     CDS             46387..47088
                     /locus_tag="ACL3GT_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516317.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            47090..48349
                     /locus_tag="ACL3GT_000614"
     CDS             47090..48349
                     /locus_tag="ACL3GT_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516318.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSSFTVSGKEEEIPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            48473..50470
                     /gene="metG"
                     /locus_tag="ACL3GT_000615"
     CDS             48473..50470
                     /gene="metG"
                     /locus_tag="ACL3GT_000615"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HGR0516319.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIIAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            50520..50663
                     /locus_tag="ACL3GT_000616"
     CDS             50520..50663
                     /locus_tag="ACL3GT_000616"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516320.1"
                     /translation="MKIKEQTRKLAAGCSKHSFEVVDETDEVSSKHSFEVVDETDEVS
                     NHT"
     gene            50801..51121
                     /locus_tag="ACL3GT_000617"
     CDS             50801..51121
                     /locus_tag="ACL3GT_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0516321.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            51125..51940
                     /locus_tag="ACL3GT_000618"
     CDS             51125..51940
                     /locus_tag="ACL3GT_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516322.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGVFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            52015..52941
                     /locus_tag="ACL3GT_000619"
     CDS             52015..52941
                     /locus_tag="ACL3GT_000619"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HGR0516323.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            53037..53273
                     /locus_tag="ACL3GT_000620"
     CDS             53037..53273
                     /locus_tag="ACL3GT_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018367459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HGR0516324.1"
                     /translation="MTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTIEQNGLALEMT
                     PYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            53266..53964
                     /locus_tag="ACL3GT_000621"
     CDS             53266..53964
                     /locus_tag="ACL3GT_000621"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HGR0516325.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDAYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEARI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            53975..54454
                     /locus_tag="ACL3GT_000622"
     CDS             53975..54454
                     /locus_tag="ACL3GT_000622"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0516326.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            54462..55190
                     /locus_tag="ACL3GT_000623"
     CDS             54462..55190
                     /locus_tag="ACL3GT_000623"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0516327.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            55232..56101
                     /locus_tag="ACL3GT_000624"
     CDS             55232..56101
                     /locus_tag="ACL3GT_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016772 - transferase activity,
                     transferring phosphorus-containing groups [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PEP-binding protein"
                     /protein_id="HGR0516328.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            56076..56516
                     /locus_tag="ACL3GT_000625"
     CDS             56076..56516
                     /locus_tag="ACL3GT_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HGR0516329.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            56639..59185
                     /locus_tag="ACL3GT_000626"
     CDS             56639..59185
                     /locus_tag="ACL3GT_000626"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008237 - metallopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HGR0516330.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
BASE COUNT        18318 a        10627 c        12754 g        17504 t
ORIGIN      
        1 tttaaaatag aaattgagaa tatgaactat tgaaagatcg gagcaatccg gtctttttat
       61 ataaagaaat tgcatataat actcatctgc tttcaaaaag cattctagtc catctccgat
      121 taacgatgga ctttatcacc tccttctcca gtccttgtat gacatcttga agttgattca
      181 tgacatcttc caaagttcga aaggccttat tcttaaatcc acgtttacga atctctttcc
      241 acacttgttc aatgggttca tctctggtgt gtatggagga ataaaggtaa aaccaatatt
      301 agtcggaatc tttaaggtac ttgatttatg ccatatagca ttgtccataa cgagtaaaag
      361 ataatcatct ggataagctt gtgaaagctc ttctaaaaag gcgttcatcc actcagtatt
      421 acatccacca gctattaaga aaaatgattc gcctgtatgg gcatcaacag ctccataaca
      481 atagtgaaat tctcgtatat agtgactatg gacatgtgga cctactccta ttggagccca
      541 acaagatccc agtttactga ttctaccgaa accagcctca tcttggtaca tcaagcgaac
      601 cttacgaaaa cgtctactgc ttttaaagcg ctttcttttc ttcttgaatt gagattttat
      661 ttttagacgc gacaatggtt tgagcgtctg ctttcctagg atgttctgga cgtggcataa
      721 tatttcgcca accatggtgc ttcaacagtt gatagaaggc atcacgtgtg taggaacgac
      781 ctaactcctt tttataagcc tgaaataagg catcaattgt aacaaattct cctgcctctg
      841 tagccttcaa atggcgggca agaaagactt tcttttcctc aatcgtcata tatgcatggt
      901 tacggccacc acgtgtttct tgaaggagag agtcgagttc gaactcctca tattttttta
      961 catttcgcca aatcgttgtt tgattacagt ctatagtgta ttgaatctat aacagtacac
     1021 cttagctgct aaaatatttc tataaattag tttgactttc ctgatagagt tgttcacatc
     1081 ttatttcaaa ctactataaa agttctataa tctctttata agatttgccc atcagacgaa
     1141 atataataaa ttgaaactag aatagtacac ctctacttct aaaacattgt tagaaatcga
     1201 tttgactgtc ctgatcgatt tgccctgttc ttgtttcgtt ttactataga acgatttgaa
     1261 ggcgtttatg atatttagct gtacgagagt ctttaaaaag tgttttgatg gtttggattt
     1321 cttctttagt tgatttcata tcactattat ataatgcttt ttgattttag tatagtatta
     1381 tcgtagaaaa tggactcggt gctatggata caccggatga gaatggttat gtagcagatg
     1441 actatcggat tacttactta gaggcccaca tcaaggccat gcgagatgcc atttacaaag
     1501 acggggttga cttgcttggt tatacgacat ggggctgtat cgattcggtt tcagctggca
     1561 caggggaaat gaataagcgc tatggtttta tctatgtaga tcgagataat gtaggaaatg
     1621 ggactctcaa acgtagcaag aagaagtcct tctattggta catgtcattt atagcaatgg
     1681 tgtaagcatc gagtagagca catttgttta ctatttttat aaaatcttct ccctgcttta
     1741 taagatgtaa aaaagagttc aattcgaact ctttttttgc tataatgagg ggagaaaaat
     1801 cagacaggag attaagatgt cagaaccatt atttttacaa tcagttatgc aagaaaaaat
     1861 ctggggtggt accaagctac gtgatgagtt tggctacgac atcccaagtg aaaaagtcgg
     1921 agagtactgg gctatctcag ctcatctaaa tggtgtttct aaagttgcca atggtcgtta
     1981 cgagggaaca gatcttgcta ctttgtatgc ggaacaccgt gaattatttg gcaatcgtcc
     2041 tgagcctgta tttccgcttt tgactaagat tttggatgct aacgactggc tcagcgttca
     2101 agttcaccca gacgatgctt atggactaga gcatgaaggc gaacttggaa aaacagaatg
     2161 ctggtacatc atcgctgcgg atgaaggttc agagattatc tacggccaca atgccaagtc
     2221 aaaagaagaa ctccgccagc aaatcgagga taagaactgg gatgcgctgt tgacaaaagt
     2281 gccagttaaa gcaggagatt tcttctatgt accaagcggt accatgcacg ctatcggggc
     2341 gggtatcttg attcttgaaa cccagcagtc tagcgatacc acttaccgtg tctatgactt
     2401 tgaccgtaag gatgacaagg gcaatttacg tgaacttcac cttgaaaaat ctatcgatgt
     2461 cttgaacatt ggtgaacccg caaatagccg tccagtgaca atcaaagcag atgatctacg
     2521 ttccactctc cttgtatcca atgatttctt cgcagtttac aaatgggaaa ttactggaaa
     2581 agttaacttt gaaaagacag ctgactacag cttgttgagt gtcttggctg gtcaaggtca
     2641 actaactgtt gacgggaaaa actatccaat ccaaaaaggg agacacttta tcctaccaag
     2701 tgatgttgaa gcttggactc tggaagggca agatttagaa ttaattgtta gtcatccata
     2761 aaaaagaaag ggcctgagtt cattactcaa gtcctttttg attacataaa ttgggcgatg
     2821 aagaccacga tgatgattgg aatgacggaa cgaagaaacg aagaaggaag agccagactt
     2881 ggaacagtcc ttgtttccat gctctttcat cgagatggag ttcctccatt gcaagagcct
     2941 ttttaaagat atagcctgta aaaagtgaaa ggtagagagc tccaaatggc atgaggagat
     3001 tgggaaccaa gaagttcata gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca
     3061 tgacaccgta agatagggct gaaggaatgc caaagacaaa ggtcaaaatt cctaaaataa
     3121 cactccattt ggcacgtttg ctgttatcct ggttggtgat attgcccaca ttgatctcca
     3181 gcatcacgac agaagaagtg acagtcgcaa agaggaagag gacgtagaaa atggttccaa
     3241 aaggcatctt gtcaaagagt tgaggcaaga cgataaagag caagctcggt cccccttcag
     3301 actggatatt gaagggggac cgagcttgga aaatggctag acctgccatg atggatatcg
     3361 agatattcat ggctacgatg gagattcctg actggactag attggttttc ttgtccaagt
     3421 aagaagcata ggtcaacatg actgtaaccc ctagtgagag ggcaaagaaa gattgtccca
     3481 gagcatagag gagaccagcg ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa
     3541 ccccttccat ggcatttggc aaactgagag agcgaccgat gataacaaca aagatgataa
     3601 agagcagggg catcatgact ttcgaagctc tttcaatccc tttttgaacc ccacgtgata
     3661 caataaagat atttaataag ataaaggctg cttgagctcc tagggcaatg gctggatttg
     3721 aaatgattga agtaaataac tgagcataat cacccgttcc accaagttgg aacaatttcc
     3781 caaactcaat acctagatag actagaatcc atcctccgat aacactgtaa aaagataaga
     3841 ggataaagag ggcaaaggcg ccaatccaac cgataaagtt gtacttgtta ttcttgccca
     3901 gttttccaaa ggttttgata gcggaaacgc cagcactacg gccaagggca aactcagcca
     3961 gcaggagagg gaaaccgatt aaaatagtgg aaatgagaaa gattagtaaa aagcctccac
     4021 cgccattagc agcagtcatg tagggaaact tccaaacgga accaagcccg atgaccgagc
     4081 cagcagatgc tagaataaag ccaagtttcg acccccattg tgatttttct gacatagtta
     4141 aactctgatc tcctttttca aaataagaaa aagctacttg agttgtcaaa tagccttctg
     4201 tttgattgat agacttgact atcctattat gttttctaag gtctgtcaag aaaacaattt
     4261 tcaagttttc acacctttct caaaaacgct tgactctgac ctaaggggag gggttatact
     4321 atcattgtaa ggaggaaatc atgtaccata taaaagaagc tgcgcagctt tcaggtgtct
     4381 ctgtcaagac cctgccctgc atcactatga caagatagga ctcttggtcc ccttaaagtc
     4441 ggaaaacggc tatcgaacct atagtcaaga ggatttggaa cgccttcagg tcattcttta
     4501 ctacaaatat ctaggctttt ctttagagaa aatagcagaa ctgttaaagg aagaaaggac
     4561 agatttattg ctccatttga ctaggtagtt ggactatcta actcgcgaaa ggcaacatct
     4621 ggataccttg atttccacct tgcaaaaaac tattcaagaa caaaaaggag aaagaaaaat
     4681 gaccattgag gaaaaattca cgggatttag ctatcaagac aatcaaaaat accaccaaga
     4741 agcggtagag aaatatggtc aagaagtcat gggacaagcg ctcgaacgcc aaaaaggtca
     4801 cgaagacgag gctacggccg cctttaacca agtctttcaa actttggcac aaaatcttca
     4861 agttggttta cctgcaacag caaccgaaaa ccaggagcaa gcagccaagc tcttgcaagc
     4921 cattcgcact tatggatttg actgctctat tgaggtattc ggtcatatcg gtaaaggtta
     4981 cgtctacaac ccagagttta aggaaaacat tgacaagttt ggttctgaaa cagcccagta
     5041 cacgtcagat gccattgcgg cttacgttca gacaaatgca gaaaaaatag gctaggaatt
     5101 tcctagccta ttttttactt caaatcataa agccagtcgt caccgttttt gtagtaaaag
     5161 aattcactga gatcttcttc tagaaacaca cgaagcatat cagacatatc atcggttgca
     5221 agttttagat gagaaagatt ttcaaagtcc tcccaccaaa ctttcccttc gtctgaagac
     5281 tggagttcac cagtaaagtg ttctgtcttg taaaaaagga cgacataacg ataatccttg
     5341 tcgtcatacc agtttttgat accacagagt tggggtttgg aaatgatcag accagtttct
     5401 tctttcactt cacgaatgac agcatcgaca aaggattcgc cacgttcaac atgaccacca
     5461 ggaaaagtaa tgccagacca gtcgggacta actcggtctt ggaccaggac cttatctccg
     5521 tttttaatca tacacatgtt aacaaattcg actgcctctc ttctgttcat tcttcacaac
     5581 ctttaatctt taatcataat gcagacttcc cgccacccag ccggtacaga gggcagaagt
     5641 gatgttaaag ccacccgtgt gggcattgat atccataact tcgcctgtaa agtggaggcc
     5701 aggtaccagc ttactttcaa gggttttagg attgatttcc ttgagactga ctccaccctt
     5761 ggtaacaaag gactttgcaa gggacatttt tccagttaca ggaattttaa gttctttaat
     5821 ggactggaca agttgttctc gttccttttc agtcagttgt ttgacttttt caggatatcc
     5881 ttgtacaaaa aattcggcca agcgttctgg taacaaggtt tttaaagcgt ttttcaagga
     5941 tttttcccga ttttcttcta gaaatgtaac caagtccttc tcagaaagtt gaggcaaaac
     6001 atcgagtgag agaacctccc cacctttgac aaagctagac atgcgtaggg cagcaggacc
     6061 tgacaaacca aagtgggtaa agagtaaatc atgagtgatg acatgcttac cataacttag
     6121 ggtcacatcg tccagagaaa tcccttgtaa ggctttatgt ggaaaatctg ttaataaagg
     6181 actttcagca gcctcaagat cggtgatggt atgcttaaaa tggcgagcaa tctcgtgacc
     6241 aaaaccagtc gaaccagtcg aaggataaga cttaccacct gttgtgacaa tgagtttctc
     6301 acaagtgaag gtttgatccg ctgacttaag gacaaactgg tcatctactt ttttaacaga
     6361 aacgatttct atttgagtag caacttgacc acctagttcg gtgattttct tttccaaagc
     6421 ttcgataata gtccgagact tgtcactggc tggaaagacg cgtccgtggt cttcgacctt
     6481 aagtttaaca ccattttctg taaaaaagtt gatgatgtca tgattatcga actgggagaa
     6541 aacactgtaa agaaagcgtc cgtttccagg aattccagct agcaggttgt ctaagctacc
     6601 attgttggtc acattgcaac gtcccccacc agtcccagct aatttttttc caagtttccg
     6661 atttttttcg atgaggaggg ttttctgtcc ataaaagcta ctggaaatcg tagccatcat
     6721 accagcaggt cccccaccga tgacaatagt atcaaaatgt ttcatagctc tattgtacca
     6781 caaaaaaaca agagatgatg gtcacctctt gtcaagaatg caattaatca atttcatagc
     6841 ccatcagcaa accgccctct tctgcataga aactgcagag accagaggtt ggtagaattt
     6901 taatatccgc ttgtgggaag gtttcacgga ttcgctctga gagctgttga caacattttt
     6961 cgttattgcg ttgggccatg acaatacggc caccagcata tccagctttt actaactcat
     7021 cataggcagc ttgaactgat ttctttgatc cccttgcttt ttgtagcaat tcgagagttc
     7081 cagtttcact agcttttccg accatacgaa tgttgagaag gccaacgacc gtaccgataa
     7141 gcttgctcaa acggccgttc ttcaccaagt tatcgacttt ggctaggaca aagagcaact
     7201 tagttttttc ttgataggca gtgatagctt caaccacttc ttcaaaagac aagccctggt
     7261 caatcaagtc attcaatttt tctacgagta ggtcaacttc accaccagca gataaactat
     7321 caatcacatg aatcttagtg tcaggatggt cttctagata aatattcttt gctagttgag
     7381 cactattgtg actgccagaa agggtacctg tgatggttac taggaaaatg tttttggcac
     7441 cttcaaatgc tcgcaaatag tcatctgggc ttggacaagc cgattttgaa gcttctgcag
     7501 ttgcatacat ggtttccatc atttggtcaa tatcgagact ggcgtcatca acaaagacct
     7561 gatcagctac ttgaatggtt aaggggacac ttacaaaggt tgtgttaata gctggtgttg
     7621 gcagttgacg ataatcacaa ccagagtcag caataatttt ccaagtcata gaaattctcc
     7681 atctttgtca gttatacatt gacaaaggtt ctgtcttttt ttacaattat atcatgaaaa
     7741 cccttgaaac aaaagcatca tccgtctgtt gtgacaagta gaaagaaaat gttatgtctg
     7801 aacgtagaat ctctgaaaag tctcttgaaa atctcagaaa atcaaaccaa gaatccaatt
     7861 tattaaccag agaagccatt gaaacagccc tcttgcaact cttggaaaaa aaggagctga
     7921 ccaagattag tatttctgaa ttggtcaaac gtgcaggtgt ttcgcgtgcg gccttttatc
     7981 gcaattatga ctccaaagag gaaattttag agagcgtctt taaacgaact gtccacaata
     8041 ttatggaaca gctgcatcat tacgatttaa agacagacct ttatttggtt tgggttcacc
     8101 ttttccggga ggccagaaag gaagctagag tgattcaatt ggccttggat taccatctgg
     8161 aaaaaatctt tgtccaagcc atgcaggaat ttctagaaaa ataccatggg aaatcaaaag
     8221 gtgtcagctc ttatcttcat tccttctgga gctcagccat cgtctctgtc cttctaaaat
     8281 ggatcaagga tggcatgaag gtaccagctg aaaagattgc agatttaggt ttaccatttt
     8341 ttaaaaaata gagaaaaagg agaaaagaga tgactgaaaa aagactggcc tgggatgagt
     8401 attttgcagc ccaagcccta ctaattgcga atcgttccac ttgtaaacgt gctaaagtgg
     8461 gcgcgattct ggtaaaagat aataaggtta tttccactgg ttacaatggt tcggtgtcag
     8521 ggactgagca ttgtattgat cacgaatgtt tggtcattga aggccactgt gttcgcaccc
     8581 ttcacgctga ggtcaatgct atccttcaag gtgctgagcg tggtgttccc aaaggcttta
     8641 cagcctatgt aacccatttt ccttgtctca actgtacaaa acaattgctt caggtcggct
     8701 gcaagcgcgt ggtttatatc aaccagtacc gaatggacga ctacgcccaa tacctttatc
     8761 aagaaaaagg gacagaattg acccatttac cacttgagac agtacagaca gctcttaaag
     8821 aggctgatct aatgtaaaaa ttatcaaaaa taaatggctt agaaagattt ttaaaccgtt
     8881 ttttggtata ataagaagaa taaattgaaa gaaggaattc caaaaatggg aaaaattgaa
     8941 gttattaatc acccactgat tcaacacaaa ttgtcaatct tgcgtcgtac agatacttct
     9001 acaaaagctt ttcgtgagct agtagatgag attgcaatgt tgatggggta tgaagtactt
     9061 cgtgatcttc cactagaaga tgtggaaatc gaaacaccaa ttacaaaaac agttcaaaaa
     9121 caattggcag gtaagaaatt ggccatcgtc ccaatcttgc gtgcaggtat cgggatggtt
     9181 gatggtctct tgagcttggt tccagctgct aaagttggcc acatcggtat gtaccgtgat
     9241 gaagaaacac ttcaaccagt tgaatacttg gtgaaattgc ctgaggacat tgaccaacgt
     9301 caaattttta tagtagaccc aatgttggca acaggtggct cagcaatctt ggctgttgat
     9361 tctcttaaaa aacgtggcgc atcaaatatc aaatttgtct gccttgtatc tgctccagag
     9421 ggtgtaaaag cccttcaaga agctcatcca gatgtagaaa tctttacagc agccttggat
     9481 gaacgtttga acgaacacgg ttatatcgtt ccaggtcttg gagatgctgg agaccgcttg
     9541 ttcggtacaa aataagatcg aaaagaagaa tgacttggaa aagtatttcc agtcacgaaa
     9601 ggaggttggg tttttgtttc tgtctaatga aagcagagca aaaatttgac cttttttgac
     9661 caagatatta taatagtctt atcttcagtc atttgaccaa caaaattaaa actcaaaagg
     9721 agaaatgaat gattcctgta gttattgaac aaacaagccg tggagaacgt tcttacgata
     9781 tttactcacg tcttctcaaa gaccgcatca ttatgctgac aggtccggtt gaagacaata
     9841 tggctaactc tgttattgcc caattgcttt tcttggatgc ccaagatagt acaaaagata
     9901 tttaccttta tgtcaataca ccaggtggtt ctgtttcagc tggtttggca atcgtagata
     9961 ccatgaactt tatcaaggca gatgtccaaa ccattgttat gggaatggct gcatctatgg
    10021 gaacagtcat cgcatcaagt ggagcaaaag gcaaacgttt catgcttcca aatgctgaat
    10081 acatgattca ccaaccaatg ggcggtacag gtggtggtac ccaacaaact gatatggcta
    10141 tcgctgcaga acacttgctc aaaactcgta ataccttgga aaaaatcttg gctgaaaatt
    10201 caggtcagtc aatggaaaaa gtccatgcag atgcagaacg tgataactgg atgagcgccc
    10261 aggaaacact tgaatatggc tttattgatg aaattatggc caacaattca ttgaactaat
    10321 gatgatagaa ggcaaactcg actgggtttg ctttttttgg tataataggg agagatttct
    10381 tagaaagagg atttatcatg tttgaaaaag tcaatcgctc tggcttgatt atctatcttt
    10441 actataatcg tgatgccaaa aaactgcagg attatggaga tattacctat cattccaaga
    10501 aacatcgtta cttacaactc tatgttccaa ctcaagaagt ggagcaattg gtcggacgct
    10561 tgagcaagga aaaatttatt aaaaaagtta gggtttgtca tatccaagag ttggaaacac
    10621 cctttgtggg caatctttat cgataggaaa acgttatcat cgaaaaagtt caaggaaaac
    10681 attgacaatt ttctgataat tcggtatatt cttaacagac tatttaagaa ataaggagac
    10741 aaaaagatga agaaaaaatt tgccctatcg tttgtggcgc ttgcaagtgt agcacttctt
    10801 gcagcctgtg gagaagtgaa gtctggagca gtcaacactg ctggtaactc agtagaggaa
    10861 aagacaatta aaatcgggtt taactttgaa gaatcaggtt ctttagctgc atacggaaca
    10921 gctgaacaaa aaggtgccca attggctgtt gatgaaatca atgccgcagg tggtatcgat
    10981 ggaaaacaaa tcgaagtagt cgataaagat aataagtctg aaacagctga ggctgcttca
    11041 gttacaacta accttgtaac ccaatctaaa gtatcagcag tcgtaggacc tgcaacatct
    11101 ggtgcgactg cagctgcggt agcgaacgct acaaaagcag gtgttccctt gatctcacca
    11161 agtgcgactc aagatggatt gactaaaggt caagattacc tctttattgg aactttccaa
    11221 gatagcttcc aaggaaaaat tatctcaaac tatgtttctg aaaaattaaa tgctaagaaa
    11281 gttgttcttt acactgacaa tgccagtgac tatgctaaag ggattgccaa atctttccgc
    11341 gagtcataca agggtgaaat cgttgcagat gaaactttcg tagcaggtga cacagacttc
    11401 caagcagccc ttacaaaaat gaaagggaaa gactttgatg ctatcgttgt tcctggttac
    11461 tataatgagg ctggtaagat tgtaaaccaa gcgcgtggta tgggaattga caaaccaatc
    11521 gttggtggtg atggattcaa cggtgaggag tttgtacaac aagcaactgc tgaaaaagca
    11581 tcaaacatct actttatctc aggcttctca actactgtag aagtttcagc taaagctaaa
    11641 gccttccttg acgcttaccg tgctaagtac aatgaagagc cttcaacatt tgcagccttg
    11701 gcttatgatt cagttcacct tgtagcaaac gcagcaaaag gtgctaaaaa ttcaggtgaa
    11761 atcaaggata accttgctaa aacaaaagat tttgaaggtg taactggtca aacaagcttc
    11821 gatgcagacc acaacacagt caaaactgct tacatgatga ccatgaacaa tggtaaagtt
    11881 gaagcagcag aagttgtaaa accataatag aaaaatgttg aaatagggaa tgagcctttg
    11941 actcactccc tgtttcgata tttaatactc ttcgaaaatc tcttcaaact gcgtcaacgt
    12001 cgccttggat tatatatgtg actgacttcg tcagtcttat ctacaacctc aaagcagtgc
    12061 tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga gtataagaac
    12121 ctatcaaaaa gtgagggaaa cccctcggaa ttataaatag aaagagtgaa tcttatgctc
    12181 caacaactcg taaatggttt gattctaggt agtgtttacg cgctgttagc cctaggatat
    12241 accatggttt acggaattat caagctcatc aacttcgccc atggtgatat ttatatgatg
    12301 ggagccttta tcggttattt cttgatcaat tctttccaaa tgaatttctt tgtagcgctt
    12361 attgtagcta tgctagcgac agctattctt ggtgtcgtga ttgagtttct tgcttaccga
    12421 cctttgcgcc actctactcg tattgctgtt ttgattacgg ctattggggt ttctttccta
    12481 ttggagtatg gaatggtcta tctggttggt gccaataccc gtgccttccc tcaagcgatt
    12541 caaacagttc gatatgattt gggaccaatt agcttaacaa atgtgcagtt aatgattttg
    12601 gctatttcct tgattttgat gattttgtta caagtcattg tccaaaagac taagatgggg
    12661 aaagccatgc gtgcagtatc agtagatagc gacgcggcgc aattgatggg gatcaatgta
    12721 aaccgtacga ttagctttac cttcgctttg ggttctgctc ttgcgggtgc ggctggtgtt
    12781 ctgattgctc tttattataa ctctcttgag cctttgatgg gggttactcc aggtcttaaa
    12841 tctttcgttg ccgcagtact tggtggtatc ggaattattc ctggtgcggc tcttggtggc
    12901 tttgtgattg gtctattgga aacctttgcg actgcctttg ggatgtcaga tttccgtgat
    12961 gccattgttt atggaatctt gttgttgatc ttgattgtcc gcccagctgg tatccttggt
    13021 aagaatgtga aagagaaggt gtaaacgatg aaggaaaatt taaaagttaa tattctatgg
    13081 ttactccttt tgttagctgg ctatagcttg attagtgtac tggtttcagt cggagtactt
    13141 aatctattct atgtacagat tttacagcaa attggaatta atattatttt ggctgttggt
    13201 ctcaacttaa tcgttggttt ttcaggacaa ttttcacttg gtcatgctgg tttcatggcg
    13261 attggtgcct atgcagcagc tattattggt tctaaattac caacctacgg tgccttcttt
    13321 ggagctatgc ttgtaggggc tttgctttca ggagcagttg ccttacttgt cggcattcca
    13381 accttgcgct tgaaggggga ctatcttgcg gtagcaactc tgggtgtttc tgaaattatc
    13441 cgtatcttta tcatcaatgg tggaagcctt acaaatggtg cggcaggtat cttagggatt
    13501 cctaacttta caacttggca aatggtttac ttctttgtcg tgattacaac cattgcaacc
    13561 ttgaacttct tgcgtagccc aattggtcgt tcaaccctct ctgttcgtga agatgaaatc
    13621 gctgctgagt cagttggggt taatacgact aaaattaaaa tcatcgcttt tgtctttggt
    13681 gccattactg caagtattgc tgggtcactt caggcaggat ttatcgggtc tgttgtaccg
    13741 aaagattaca ccttcatcaa ctcaatcaac gttttgatta ttgttgtatt tggtggactc
    13801 ggttccatta caggtgcgat tgtttcggct attgttctgg gaattttgaa tatgcttctc
    13861 caagatgttg ctagtgtgcg tatgattatt tacgctttgg ccttggtatt ggtaatgatt
    13921 ttcagaccag gtggactcct tggaacatgg gaactgagcc tatcacgttt ctttaaaaaa
    13981 tctaagaagg aggaacaaaa ctaatggcat tacttgaagt aaaacagtta accaaacatt
    14041 ttggtggtct aacagctgtt ggagatgtga ctcttgaatt gaacgaaggg gaactggttg
    14101 gattaatcgg tccaaacgga gctgggaaaa ccaccctttt caaccttttg accggtgttt
    14161 atgaaccaag cgagggaaca gtaaccctag atggtcacct tttgaatggg aaatcacctt
    14221 ataagattgc ctctttggga cttggacgta ctttccaaaa tatccgtctc tttaaagatt
    14281 taacagtttt agacaatgtt ttgattgctt ttggaaacca tcacaaacaa catgttttta
    14341 ctagtttctt acgcttacca gctttttaca agagtgaaaa agaattaaag gctaaagctt
    14401 tggaattgtt gaaaatcttt gatttagatg gtgatgcaga gactcttgct aaaaatcttt
    14461 cctacggaca acaacgtcgt ttggaaattg ttcgtgccct tgctacggaa cctaaaattc
    14521 tcttcttaga tgaaccagca gcaggtatga acccacagga aacagccgaa ttgactgagt
    14581 taattcgtcg tatcaaagat gaatttaaga ttacaatcat gttgattgaa cacgatatga
    14641 atctggtcat ggaagtaaca gaacgtatct acgtacttga atatggccgt ttaattgctc
    14701 aaggaactcc agacgaaatt aagaccaata aacgcgttat cgaagcttat ctaggaggtg
    14761 aagcctaatg tctatgttaa aagttgaaaa tctttctgtg cattacggta tgatccaagc
    14821 agtccgtgat gtaagctttg aagttaatga aggagaagtt gtttccctta tcggtgccaa
    14881 cggtgcaggt aagacaacta ttcttcgcac cttgtcaggt ttggttcgac caagttcagg
    14941 aaagattgaa tttttaggtc aagaaatcca aaaaatgcca gctcagaaaa ttgtggcagg
    15001 tggtctttca caagttccag aaggacgcca cgtctttcct ggcttgactg ttatggaaaa
    15061 tcttgaaatg ggagctttct taaagaaaaa tcgtgaagaa aatcaagcta acttgaagaa
    15121 ggttttctca cgctttcctc gtcttgaaga acgtaagaac caagatgcag ctactctttc
    15181 aggaggggaa caacaaatgc ttgccatggg acgcgctctt atgtcaacac caaaacttct
    15241 tcttttagat gaaccatcaa tgggacttgc cccaatcttc atccaagaga tttttgatat
    15301 cattcaagat attcagaagc aaggaacaac cgtcctcttg attgaacaaa atgccaataa
    15361 agcacttgca atctctgacc gaggatatgt actggaaaca gggaaaatcg tcctatcagg
    15421 aacaggaaaa gaactcgcct catcagaaga agtcagaaaa gcatatctag gtggctaaaa
    15481 caatccagtg gattgtttta gtcggcagat gaagattacg aagtaatcat cattatagtc
    15541 tgggagacta gtttaggttg cagataaaga ttgcgaagca atcatcaaat ccagtggatt
    15601 gttttagtcg gcagatggag attacgaagt aatcatcaat atagtccggg ggaccttttt
    15661 agtcggtaga ttgagattgc aaacaaatct gcatctacat tgaaagctta atttctaata
    15721 attgaaaaaa tcgaatgaaa aatttcttac cttcattcac agagctcgat ttcagagctc
    15781 tttttgctag cttattcata cttttctgaa tttcgaaaaa gaaatgtaag cgtttgatag
    15841 atttacaaaa agattgtata atagggataa gaatagaaaa ggagaagtct catggcagtt
    15901 aaagatttta tgacccgcaa ggtagtttat attagtccag atacaacagt atctcatgca
    15961 gcagatttga tgagagagca aggtttgcac cgtctgcctg ttatcgaaaa tgatcaatta
    16021 gttggtttgg tgactgaggg aaccattgca caagcaagtc catctaaagc aacaagtctt
    16081 tctatctatg agatgaatta tcttctgaat aagacaaaag taaaagatgt catgattcgc
    16141 gatgttgtca ctgtctcagg ctatgctagt ctagaagatg caacttatct gatgttgaaa
    16201 aataagatta gtattctccc tgtcgtagat aaccatcaag tatacggagt tattactgac
    16261 cgtgacgttt tccaagcctt tcttgaaatt gcaggttatg gcgaagaagg gattcgtgta
    16321 cgctttgtta cagaagatga agttggtgtt cttggaaaaa ttgtttcttt gattgtagaa
    16381 gaaaatttga atatctccca tacagtcaat attccgcgta aggatggtaa ggtgattatc
    16441 gaagtgcaaa tcgatggatc aattgattta ccagccttga aagaaaaatt tgaagcaaat
    16501 ggtattcaag tggaagaaat cgctcgcact tcagcaaaag tcttgtaaga agggaagccc
    16561 aaaggcttct tttttcatga aaaggggatt agagaaaaag atggaaagaa atgataaaat
    16621 atgctataat gaaataatgt aaaaaaggag tatttatgga catttcagta attcgtcaga
    16681 aaattgacgc aaatcgtgaa aaattagctt ctttcagggg gtctctttga cctcgaaggg
    16741 ctagaggagg agattgccat cttggaaaac aagatgacag aacctgattt ttggaacgat
    16801 aatattgcag cccaaaaaac gtcgcaagaa ttaaatgaat taaaaaacac ttacaatacc
    16861 ttccataaga tggaagagtt gcaggatgaa gtcgaaattt tattggattt tttggctgaa
    16921 gacgagtcag tgcatgatga actggtagcg cagttagccg aacttgataa gataatgacc
    16981 agctacgaga tgactctact cttgtcagaa ccttatgacc acaacaatgc catcttggaa
    17041 atccatccag gttctggtgg tactgaggcg caggactggg gtgatatgtt gcttcgtatg
    17101 tatactcgtt atggtaatgc taaaggcttt aaagtggaag tgttggatta ccaagcaggt
    17161 gatgaggctg gtattaagtc ggtaacttta tcatttgaag ggcctaatgc ctatggtctc
    17221 ctcaagtcag aaatgggtgt tcaccgctta gtgcgaatct caccatttga ctctgccaaa
    17281 cgtcgccata cctctttcac atctgtagaa gtgatgccag aattggatga tactattgaa
    17341 gtggaaatcc gtgaagatga tatcaagatg gataccttcc gttcaggtgg tgccggtgga
    17401 caaaacgtca ataaggtttc aacaggtgta cgtttaaccc acattccaac tggaattgtt
    17461 gtccaatcaa cagtggatcg tacccagtat ggaaatagag atcgtgccat gaagatgttg
    17521 caggctaagc tctatcaaat ggagcaagag aagaaggctg cagaggtaga ttctctcaaa
    17581 ggtgagaaaa aggagatcac ttggggaagc caaatccgtt cttatgtctt cacgccttat
    17641 actatggtaa aagatcaccg aactagcttt gaggttgctc aggtagataa ggttatggat
    17701 ggggacttag atggttttat cgatgcttat ctcaagtggc gaattagcta agatagaaag
    17761 gaactcacat gtcaattatt gaaatgagag atgtcgttaa aaaatacgac aacggaacga
    17821 ctgctctacg cggtgtttcg gttagcgttc aaccggggga atttgcttac atcgtaggac
    17881 cttcaggagc agggaagtca acttttattc gttctctgta tcgtgaagta aaaatcgata
    17941 aaggaagcct atcagttgct ggttttaatc tggttaagat caaaaagaaa gatatcccgc
    18001 ttctacgtcg tagtgttggg gttgtcttcc aggattataa attgttacca aagaaaactg
    18061 tctatgaaaa tattgcttac gctatggaag taatcgggga aaatcgccgt aatatcaaaa
    18121 gacgagtgat ggaagttttg gacttggttg gattgaagca taaggttcgt tctttcccaa
    18181 atgaactctc aggtggggag caacagcgga ttgcgattgc gcgtgcaatt gtaaataatc
    18241 ccaaagtatt gatagctgat gagccaacag gaaatctgga tccggataat tcatgggaaa
    18301 ttatgaatct tttggaacgg attaacctac aaggaacaac tattttgatg gcgactcata
    18361 atagccagat tgtaaatacc ttgcgccacc gtgtcattgc cattgaaaat ggccgtgtcg
    18421 ttcgtgacga atcaaaagga gagtatggat acgatgatta gtagattttt tcgccattta
    18481 tttgaagcct taaaaagttt gaaacgaaat ggttggatga cagtagctgc tgtcagttca
    18541 gtcatgatta ctttgacctt ggtggcaata tttgcatctg ttattttcaa tacagcgaaa
    18601 ctagctacag atattgaaaa taatgtccgt gtagtagttt atatccgaaa ggatgtggaa
    18661 gataatagtc agacaattga aaaagaaggt caaactgtta caaataatga ctaccacaag
    18721 gtatatgatt ctttgaagaa catgtctacg gttaaaagtg ttaccttttc aagtaaagaa
    18781 gaacaatatg aaaaattaac cgagataatg ggagataact ggaaaatctt tgaaggagat
    18841 gccaatcctc tctatgatgc ctatattgta gaggcaaaca ctccaaatga tgtaaaaact
    18901 atagccgaag atgctaaaaa aattgaaggt gtctctgagg ttcaagatgg cggtgccaat
    18961 acagaaagac tcttcaagtt agcttcattt atccgtgttt ggggactagg gattgctgct
    19021 ttgttaattt ttatcgcagt tttcttgatt tcaaatacca ttcgtattac cattatttcc
    19081 cgcagtcgcg aaattcaaat catgcgcttg gtcggagcta aaaacagtta tatccgtgga
    19141 ccgttcttgt tagaaggagc ctttatcggt ttattgggag ctatcgcacc atctgttttg
    19201 gtctttattg tttatcaaat tgtttaccaa tctgtcaaca aatcgttggt agggcaaaat
    19261 ctatccatga ttagtccaga tttatttagt ccgttgatga ttgccctact atttgtgatt
    19321 ggggttttca ttggttcatt gggatcagga atatccatgc gccgattctt gaaggtttag
    19381 gtaaaatagc tgcttttatg aggagattgt aaaatctcct tttttgctac aagagttttt
    19441 gaaaagagat gcgcagaaga aaagagcttc caaagaagtc ccccagagaa gacttcttga
    19501 tggctaattt gaacttgaaa tttggcgcac tagaaatttt ttagaaaaaa gtgtaatttt
    19561 tttataaaag cctttacaaa aaaaattaaa gtggtataat taaatcatag aaagtgcaaa
    19621 cgttttcgta aaacgtttgc ctaaataaaa ataaaggaga tttgaatgat gaaagataca
    19681 ttcaaaaatg tcttgtcttt cgaattttgg caaaaattcg gtaaggcttt gatggtagtt
    19741 atcgcggtta tgccggctgc tggtttgatg atttcaatcg gtaagtctat cgtgatgatt
    19801 aacccaacct ttgcaccact tgtcatcaca ggtggaattc ttgagcaaat cggttggggg
    19861 gttatcggta accttcacat tttgtttgcc ctagccattg gaggaagctg ggctaaagaa
    19921 cgtgctggtg gtgctttcgc cgctggtctt gccttcatct tgattaaccg tatcactggt
    19981 acaatctttg gtgtatcagg cgatatgttg aaaaatccag atgctatggt aactactttc
    20041 tttggtggtt caatcaaagt tgctgattac tttatcagtg ttcttgaagc tccagccttg
    20101 aacatggggg tattcgtagg gattatctca ggttttgtag gggcaactgc ttacaacaaa
    20161 tactacaact tccgtaaact tcctgatgca ctttcattct tcaacgggaa acgtttcgta
    20221 ccatttgtag ttattcttcg ttcagcaatc gctgcaattc tacttgctgc tttctggcca
    20281 gtagttcaaa caggtatcaa taacttcggt atctggattg ccaactcaca agaaactgct
    20341 ccaattcttg caccattctt gtatggtact ttggaacgtt tgctcttgcc atttggtctt
    20401 caccacatgt tgactatccc aatgaactac acagctcttg gtggtactta tgacatttta
    20461 actggtgcag ctaaaggtac tcaagtattc ggtcaagacc cactatggct tgcatgggta
    20521 acagaccttg taaaccttaa aggtactgat gctagtcaat atcaacactt gttagataca
    20581 gtacatccag ctcgtttcaa agttggacaa atgatcggtt cattcggtat cttgatgggt
    20641 gtgattgttg ctatctaccg taatgttgat gctgacaaga aacataaata caaaggtatg
    20701 atgattgcaa cagctcttgc aacattcttg acaggggtta ctgaaccaat cgaatacatg
    20761 ttcatgttca tcgcaacacc tatgtatctt gtttactcac ttgttcaagg tgctgccttc
    20821 gctatggctg acgtcgtaaa cctacgtatg cactcattcg gttcaatcga gttcttgact
    20881 cgtacaccta ttgcaatcag tgctggtatt ggtatggata tcgttaactt cgtttgggta
    20941 actgttctct ttgctgtaat catgtacttt atcgcaaact tcatgattca aaaattcaac
    21001 tacgcaactc cagggcgcaa cggaaactac gaaactgctg aaggttcaga agaaaccagc
    21061 agcgaagtga aagttgcagc aggctctcaa gctgtaaaca ttatcaacct tcttggtgga
    21121 cgtgtaaaca tcgttgatgt tgatgcatgt atgactcgtc ttcgtgtaac tgttaaagat
    21181 gcagataaag taggaaatgc agagcaatgg aaagcagaag gagctatggg tcttgtgatg
    21241 aaaggacaag gggttcaagc tatctacggt ccaaaagctg acattttgaa atctgatatc
    21301 caagatatcc ttgattcagg tgaaatcatt cctgaaactc ttccaagcca aatgactgaa
    21361 gcacaacaaa acactgttca cttcaaagat cttactgagg aagtttactc agtagcagac
    21421 ggtcaagttg ttgctttgga acaagtaaag gatccagtat ttgctcaaaa aatgatgggt
    21481 gatggatttg cagtagaacc tgcaaatgga aacattgtat ctccagtttc aggtactgtg
    21541 tcaagcatct tcccaacaaa acatgctttt ggtattgtga cggaagcagg tcttgaagta
    21601 ttggttcaca ttggtttgga cacagtaagt cttgaaggta aaccatttac agttcatgtt
    21661 gctgaaggac aaaaagttgc agcaggagat ctccttgtca cagctgactt ggatgctatc
    21721 cgtgcagcag gacgtgaaac ttcaacagta gttgtcttca caaatggtga tgcaattaaa
    21781 tcagttaaat tagaaaaaac aggttctctt gcagctaaaa cagcagttgc taaagtagaa
    21841 ttgtaatata cttgaggttg gaagctgtat tccaacctct tattttggga gaaaagaatg
    21901 aaatttttaa cactcaatac tcacagttgg atggagaaag aagcagagga aaaattccag
    21961 attttgcttg aagatattct tgaaaaggac tatgatttga tttgtttcca agaaatcaat
    22021 caggagatga cctcgtcaga ggtggaggtt aatgaccttt atcaagcttt gccagcagct
    22081 gagcctattc accaagacca ttatgttaga ctcttggttg aaaagttgtt agagcaaggg
    22141 aaaaattact actggacctg ggcttataac catatcggct atgaccgcta ccacgaaggt
    22201 gtggctatct tgtctaaaac acctattgaa gccagagaaa ttttggtttc agatgtggat
    22261 gatccaacag actatcatac tcgccgtgtt gccctagctg aaactgtagt cgatggcaag
    22321 gagctagcag ttgccagtgt tcatctctct tggtgggata aaggtttcca agaagaatgg
    22381 gcacgatttg aggctgtctt gaaaaaattg aacaagccac ttttactagc tggagatttt
    22441 aacaacccag caggtcagga aggttaccaa gctattttag ctagtccatt aggcttacaa
    22501 gacgcatttg aagttgctca agagaaaagt ggtagctata ctgttccgcc tgaaattgat
    22561 ggctggaaag ggaacactga accccttcga atcgattatg tctttactac caaagagtta
    22621 gcggtggaaa atttacatgt cgtatttgat ggtaacaaga gtccacaagt gagtgatcac
    22681 tatggcttga atgctatatt aaactggaaa taataactga aaagaggttg gaactataaa
    22741 attccagcct tttcttacta gagaagctac tggaaatagc ctaaataagt gagactactg
    22801 taatggaata aaatatggta taattgataa ggtagataga atcgaggatg ttatgtcatt
    22861 tacgaaattt caatttaaaa actatattag agaagccttg aaggagttaa aatttacaac
    22921 tccaacagag gtgcaagaca agttgattcc tattgttttg gcaggtcgtg acctagtagg
    22981 agaatcaaaa acaggttcag gtaagactca tactttcttg ttaccgattt tccagcaatt
    23041 agatgaagct agcgatagtg tacaagcagt gattactgca ccgagtcgtg agttggctac
    23101 tcaaatttac caagtagcgc gtcagatttc agctcactca gatgtcgaag ttcgtgtggt
    23161 taattatgtg ggtggtacgg ataaggctcg ccagattgag aaattggcaa gcaatcagcc
    23221 tcatattgtt attggaacac caggccgtat ctacgacttg gttaaatctg gtgatttagc
    23281 tattcataaa gccaagacat ttgttgttga tgaagcagat atgaccttgg atatgggatt
    23341 cttggaaact gttgataaga ttgctggcag tcttccaaaa gacttgcaat tcatggtctt
    23401 ctcagcgact atcccacaaa aactgcaacc attcttgaaa aaatacttat caaatcctgt
    23461 tatggagaaa attaagacca aaacggttat ttctgacacc attgataatt ggttgatttc
    23521 gaccaaggga catgataaga atgctcaaat ttaccagttg actcagttga tgcagccgta
    23581 tttggcaatg atttttgtta acactaaaac acgtgctgat gaattgcatt catatctgac
    23641 tgctcaaggc ttgaaggttg caaaaatcca tggagatatt gcccctcgtg aacgcaagcg
    23701 aatcatgaat caggtgcaaa atctggattt tgagtatatt gtcgcaacag atttggcagc
    23761 gcgtgggatt gacattgaag gtgtcagcca tgtcatcaat gatgccattc cgcaagactt
    23821 atcttttttt gttcatcgtg ttggtcgtac tggacgaaat ggcctaccag gtacagctat
    23881 taccctttat cagccaagtg atgactcgga tatccgtgag ttggagaaat tgggaatcaa
    23941 gtttagtcct aagatggtca aagacgggga atttcaagat acctatgacc gtgatcgtcg
    24001 tgccaaccgt gagaaaaaac aagataaact tgatatcgaa atgattggtt tggttaaaaa
    24061 gaaaaagaaa aaagtcaaac cgggttataa gaagaaaatt caatgggcgg ttgatgaaaa
    24121 gcgccgtaaa accaagcgtg ctgaaaatcg cgctcgcggt cgtgcagagc gtaaagctaa
    24181 acgccaaaca ttttaataga aattgttgga gtattgagct ccaacttttt tatttatgag
    24241 aacgaactat ctaaaccgaa acactacatt aaagactgca aattgcgatt aaaaatggta
    24301 taatgataaa gttatatagt cccgataaga tggtaggtat ttattacgaa gagttttcct
    24361 atcagtactt tgtaactcta taacaatatt ttttaagggg gggacatttt tatgtcagag
    24421 cgtaaattat tcacgtctga atctgtatct gaggggcatc cggataagat tgcagaccaa
    24481 atttcagatg cgattttgga tgctatttta gcaaaggatc cagaggcgca cgttgctgct
    24541 gaaacagctg tatatactgg ttctgtccac gtttttggtg aaatttctac aaatgcctat
    24601 gtggatatta accgtgtggt tcgtgatacc attgcagaga ttggttatac caatacagaa
    24661 tatggatttt ctgctgagac ggtgggagta cacccatctt tggtggaaca atctcctgac
    24721 atcgctcaag gtgttaacga agccttggag gttcgtggaa atgctgatca agatccactg
    24781 gacttgattg gagcaggtga ccaagggctc atgtttggat ttgcagtaga tgaaacagaa
    24841 gagctcatgc cattgccaat tgcactcagt cataaattgg ttcgtcgtct ggcagaactt
    24901 cgtaagtctg aagaaattag ctatctccgt ccagatgcaa aatcacaagt tacagttgag
    24961 tacgatgaaa atgaccgtcc ggtacgtgta gatacagtcg ttatttctac tcagcatgat
    25021 ccagaggcca ctaatgaaca aatccatcaa gatgtgatta aaaaggtcat caaagaagtt
    25081 attccatctt cttatcttga tgataagaca aaattcttta tcaatccgac aggtcgtttt
    25141 gtaatcggtg gtcctcaagg ggactcaggt ttgactggtc gtaagattat tgtagatact
    25201 tatggtggct actctcgtca tggtggtggt gccttctctg gtaaagatgc gactaaggtg
    25261 gatcgttcag cctcttatgc ggctcgctat attgccaaga atatcgttgc agcagacctt
    25321 gctaagaagg cagaagtgca gttggcctat gctatcggtg ttgcgcaacc tgtttctgtt
    25381 cgtatcgata ctttcggtac aggaacagta gctgaaagtc aacttgaaaa agcggctcgt
    25441 caaatctttg accttcgccc tgcagggatt atccaaatgc tggacctcaa gcgtccaatt
    25501 taccgtcaaa catcggctta cggtcacatg ggacgtacag atattgatct tccatgggaa
    25561 cgtttggata aggtagatgc tttgaaagaa gcagtaaaat aagattttaa gaggggaacg
    25621 tcctctcttt tttatagttt ttaactatac tgggatactg ttctgaaaat ccattttgtg
    25681 aaagtagaga tttacatgta tagtagattg aaactagaat agtacacctc aacttctaaa
    25741 acattgttag aaatcgattt gactgtcctg attgatttct cctgttcttg tttcatttta
    25801 ctatatttct ttaaaaatga taaaggttga gatttctcct cgtaatagat aatcatgggg
    25861 atatttcaat ccaaagtttt attcgttatc acttgactat tgcaaggttt tctagagcaa
    25921 cagagtcatg gaatggactc atggttgaga tttctccttg ttgcttggac ttcattcaaa
    25981 agtctgttac ccaagccttg ttcaaacttc caatacacta gctgtttcca tagcatgact
    26041 tctgtactag actttctttt ccgaataaat agatagaacc acagaatcta gtaaacctag
    26101 aattaaaatt atggtataat attagcaata aaagaaatct ggaggattag aatcatggta
    26161 tcaacgaaaa cacaaattgc tggttttgag tttgacaatt gcttgatgaa tgcagcaggt
    26221 gtggcttgta tgacgataga ggagttagaa gaggtcaaaa actcagcggc aggaaccttt
    26281 gttactaaga cagcgacctt ggacttccgt caggggaatc ctgagccacg ctaccaagat
    26341 gttccacttg gttccatcaa ctctatgggc ttgccaaata atggcttaga ctattatttg
    26401 gattatcttt tagatttgca ggaaaaagag tcgaaccgaa ctttcttctt atctctggtc
    26461 ggcatgtctc cagaggaaac ccatactatt ttgaaaaaag tccaagagag tgattttcgt
    26521 ggtctgactg agctaaatct ttcctgtcca aatgttccag gtaaacctca gattgcctat
    26581 gattttgaga caacagaccg gattttggca gaagtgtttg cttacttcac caaacctctt
    26641 ggaattaaat tgccacctta ttttgatatt gttcactttg atcaagcggc agctattttc
    26701 aacaaatatc cgctcaagtt tgtcaactgc gttaactcta tcggaaacgg cctctatata
    26761 gaagacgaat ctgtcgttat tcggcctaag aatggttttg gtggaattgg tggagaatac
    26821 atcaaaccga ctgctctagc caatgttcac gccttttatc aacgtttaaa tcctcaaatc
    26881 caaattatcg gaacaggtgg cgttctgact ggtcgagatg cctttgaaca catcctctgt
    26941 ggagcaagta tggtgcaggt gggaacgacc cttcacaaag aaggtgtcag tgcttttgac
    27001 cgcattacca atgaactgaa agcaatcatg gtggaaaaag gctacgagag cttagaagat
    27061 ttccgtggga aattgcgcta tattgactaa attaaatcga aaaatctgaa gaaaggagag
    27121 acgatgctag ccattgaaga aagtcagaag ttgactttat caaatttacc gagcctgagc
    27181 ctatttacag ggacagatca gggtcagttt gaagtgatga agagtcaagt gttgaaacag
    27241 attgggtatg attctgctga cctcaacttt gcctactttg atatgaaaga agtagtttac
    27301 aaggatgtgg aactggagtt ggtcagcctt cctttctttg cggatgagaa aatcgtgata
    27361 ttagattatt ttatggatat cacgactgct aagaaacgct ttttgacaga tgatgagctt
    27421 aagtcatttg aggaatacct tgacaatcct tctccaacaa ccaagttgat aatctttgca
    27481 gaaggaaagc tggatagcaa aagacggtta gtcaaattac ttaagcgtga tgccaaggtc
    27541 ttcgatgcag tagaagtaaa agaacaagaa ttgcgccagt atttccaaaa gtggagtcag
    27601 aaacaaggtc tgcagtttac caatcattct tttgaaaatc tcctcatcaa gtcggggttt
    27661 caatttagcg aaatccagaa aaatcttctc tttttacagt cctataaggc gaattctgtt
    27721 atcgaggaag aggatattgt taacgcaatt cccaagacct tgcaggacaa tatttttgat
    27781 ttaactcagt ttattctgac taaaaagatg gatcaggcgc gcgatttggt gagagacttg
    27841 accttgcaag gggaagatga aatcaaactg attgcagtca tgctgggaca atttcggact
    27901 tttactcagg tgaagatttt ggcggagtct ggccaaacag aatcgcagat tgcaagtagt
    27961 ttaggtagtt atctgggacg taacccaaat ccttatcaaa tcaagtttgc attaagagat
    28021 tcgagaggac tttctttgag ctttctgaag caagctattt cctatttgat tgagacagac
    28081 tatcagatta agacaggtct ttatgaaaaa ggtttccttt ttgaaaaggc actcttacag
    28141 attgctagtc aggtcaattg acatttgttg aaactacaac ccacgtcagg attatcttgt
    28201 cgtgggtttc ttgctgattt gcttatttta ttagaaagta tgtcagtgat ttccttatct
    28261 ataagcaaaa aacttgaaaa aagtgaatgt ttgcgttatc attttcatat agaaagaaaa
    28321 agaggtatta cagatggcta ttatcttacc agaacttcca tatgcatacg acgctttgga
    28381 accatacatc gatgcggaaa caatgcattt gcaccatgac aaacaccatc aaacttatgt
    28441 caacaatgcc aatgcagctt tagaaaaaca ccctgaaatc ggtgaagacc ttgaagcctt
    28501 gcttgctgat gtagaatcta tcccagctga tatccgtcaa gcacttatca acaatggtgg
    28561 cggacacttg aaccacgctc ttttctggga attgatgact cccgagaaaa cagctccttc
    28621 agcagaactg acagcagcaa tcgatgcaac atttggttca tttgaagaat tccaagcagc
    28681 cttcactgca gcagcaacaa ctcgttttgg ttcaggttgg gcatggttgg ttgtcaacaa
    28741 agaagggaaa cttgaagtga cttcaacagc aaaccaagac acaccaatct cagaaggtaa
    28801 aaaaccaatc ttgggcttgg acgtttggga acatgcttac tacgtgaaat accgcaacgt
    28861 gcgtcctgac tatatcaaag ctttcttttc agtaatcaac tggaataaag tagatgaatt
    28921 gtacgcagct gctaaataat gatagttgga gggaagaatt gttcttctct tttttaggtt
    28981 ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga aacgtgctaa
    29041 ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga tatctatgcg
    29101 aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg agttccattt
    29161 acacggggac aaggtcgaaa cggaagggat agctttttcc ttggttgaaa atatcaagga
    29221 tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtattaacca agtttgatta
    29281 tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca aggatgaccg
    29341 aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag agtattgtag
    29401 ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat catttgacaa
    29461 gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac cgactcaaac
    29521 taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc aacattctca
    29581 gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag agaataagga
    29641 gaagaaatga aaccctcaat tcatagtttg gcacatcaaa ccatgcagga atgggtattg
    29701 gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta ccgtaaacgt
    29761 gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa gctcaatgac
    29821 cagtttgtgg tcaatccctt gaaacaacgt attgtgcaag agtctgctga tggtacagtc
    29881 aaatatctct ttgaattgcc cgacggtatg ttaattgaga ctgtactcat gcgtcaacac
    29941 tatggtttat ctgtctgtgt gaccactcag gtcagctgta atatcggttg taccttctgt
    30001 gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt agcgcaaatc
    30061 atgctggttc agaaatactt tgctgatgaa ggggttcagg tcaatcttgc cgtgtctctt
    30121 cacgcaccca acaatgaact tcgttcaagt atcatgaaaa ttaaccgtgc ctttccgatt
    30181 gaaaaactct ttgctgctat tgaatactac attgagacaa caaaccgtcg tgtaaccttt
    30241 gaatatatca tgcttaatga agtcaacgac ggtgtagaac aagccttgga attggctgaa
    30301 ttgctcaaga acatcaagaa attgtcttat gtaaacttga ttccttataa cccagttagt
    30361 gagcatgacc aatatagccg tagtcccaaa gagcgcgtgt tggctttcta tgatacgctt
    30421 aagaaaaaag ggggcaactg tgtggttcgt caagagcatg gtacagatat tgacgcagct
    30481 tgtggacaat tgcgctttaa cacaatgaaa cgtgaccgcc agaaggcagt cgcagcggta
    30541 aatccttaat gatgaagaag acttataatc atattttggt ctggggagtc attttctata
    30601 gcatttgcat tgtctatttt tgctttactc ctcaagaaca atctaccgtg ggagtgggaa
    30661 ctccagatat tcagcctctt ggacgcctgg tttttctttt gactcctttc aattctctct
    30721 ggaaactggg cgaagtgagt gacattggac aattatgttg gattttttta caaaatatcc
    30781 tcaatgtctt cttgtttttt cctctgattt tccaactcct ttatctattt ccaaatttgc
    30841 ggaaaacaaa aaaggtcctt ctttttagtt ttcttgtgag tcttggaatc gagtgtacgc
    30901 aattaatctt ggactttttc tttgatttta atcgcgtctt tgagattgat gatttgtgga
    30961 ccaacacttt gggtggctat ctggcttggc tcctttataa acgattacat aaaaacaaga
    31021 taaggaatta aaatgagtat tttagaagtt aaaaatctga gtcacggttt tggtgaccgt
    31081 gcaatttttg aagatgtgtc cttccgtctc ctcaagggag aacatatcgg cctggtcggt
    31141 gccaatggtg aaggaaaatc aacctttatg agtatcgtga ctggtaaaat gctgccagat
    31201 gaaggaaagg ttgagtggtc caaatatgtg acggctggtt acttggatca gcactctgtc
    31261 cttgctgaaa gacagtcggt gcgtgatgtt ctccgtacgg cttttgatga gcttttcaaa
    31321 gctgaagctc gtatcaatga cctctatatg gaaatggctg aagacggtgc ggatgttgat
    31381 gctctcatgg aagaagtggg agaacttcaa gaccgtctgg agagtcgtga tttctatacc
    31441 ttggatgcta agattgacga agtagcgcgt gctcttggta ttatggactt tggcatggat
    31501 acggatgtaa cttctttgtc aggtgggcaa agaaccaagg tgcttttggc aaaacttctc
    31561 cttgaaaagc ctgatatttt gctgttggac gagccgacca actacttgga tgctgagcat
    31621 attgattggc tcaagcgcta tctccaaaac tatgagaatg cctttgtcct catttcgcac
    31681 gatattccat tcctcaatga cgttattaat attgtctatc atgtggaaaa tcaacagctg
    31741 acgcgttact ctggtgacta ctaccagttc caagaagttt atgctatgaa gaaatctcag
    31801 ctagaggcag cctacgaacg ccagcagaaa gagattgcag acctcaagga ctttgtggct
    31861 cgtaataaag cccgtgttgc aactcgtaat atggctatgt ctcgtcaaaa gaaattggat
    31921 aagatggata ttatcgaact ccaaagtgag aaaccaaaac catcctttga tttcaaacca
    31981 gctcgtacac cagggcgctt tatcttccaa gccaagaact tgcaaattgg ttacgaccgt
    32041 cctcttacta agcctttaaa tcttaccttc gaacgcaatc aaaaggttgc gattattggt
    32101 gctaatggta ttggaaaaac aactctcttg aagagtctct taggcattat ctcgccaatc
    32161 gctggggaag tggagcgtgg agattattta gaacttggtt attttgagca ggaagtagaa
    32221 ggcggtaatc gccaaactcc tcttgaagct gtctggaatg cctttcctgc ccttaatcaa
    32281 gcagaagtcc gtgcagccct tgcccgttgt ggtttgacaa ccaaacatat tgaaagccag
    32341 attcaagtat tatcaggggg agagcaagcc aaggttcgtt tctgtctctt gatgaatcgt
    32401 gaaaacaacg ttttagtgct ggacgagccg accaaccatt tggatgtgga tgcaaaggat
    32461 gagctcaaac gcgctctcaa agaatatagg ggatctatcc ttatggtctg ccacgagcca
    32521 gacttttatg aaggctggat agaccaaata tgggatttta ataatttaac ttaagaatga
    32581 gagtaaaaga aatacagtac cgaatgtgga tactgtattt ttttggtttt taagatttaa
    32641 aatcgtagtc tttcaccact tcgatgctgt cgattgtgat agcagtagtt ggcttgtctt
    32701 tttcatcttt ttcggcctta gcaatcttat ccacaacatc cataccgtca atcacttgac
    32761 caaagactgg gtgtttgcca tctagactag ggtttccacc ttctttgtag gcttcgataa
    32821 ttttctgtgg atacttgctt gtagggagtt tagaagaggt atctgtagag ttttggttga
    32881 tgaagaactg gctgccattg gtgtttggtt gaccagtatt agccatagca agagcaccac
    32941 ggatgttata caaataagga gtaatctcgt tcttgaaacc agttcctttg tctttagtct
    33001 tatccttgtc atgccagatg gactgaccac ctgtaccgtc cccttttgga tctccagttt
    33061 ggaccataaa gccatcgatg acacggtgga aggtaatacc gttatagtag ccttctttgg
    33121 cgtgagtgag gaaattttca accgctagag gagcgagttt agggaagagt ttaatgcgaa
    33181 tatcaccttg gcttgtgtgg agaatcactt cggcttcatc ttcagcaact tccttagata
    33241 gttgtgggaa attggcgttt tcgtttgtta aagcatcgtt taactccttg gcagattggg
    33301 cagctacttt ggaactttct tcagcagcaa gactggaatc aacataatca tcaccacgca
    33361 gactgcgttg gacgctgcta cacccagcta gggctacagt agacagtaaa agaagggttg
    33421 ctagtttttt cattctgatc ctctcaaaaa ttcatttata accattgtac cctaaaagga
    33481 agtggatttc aaatattagt agtttacaga actggcttag ataatagttg ggatttcatc
    33541 atcatcttga aaatcttcaa cttcttcccc agtaaatggt ttctgaaaag aacttagtat
    33601 aaaacgggca attggttcaa caattaggaa atttagagga agagctgcaa taaagtttac
    33661 gaaccaggcg cttagatagg tattgggtgt gatagcaatg ccattgtaaa aaaagtccat
    33721 agaaggacat gaaagtgacc agctaattct tcttctgaaa aatgctcatg aagggcttga
    33781 tccaggtcgc aagatttcat tttagaaagt ccagtaactc ccttcttctt caggatattc
    33841 tttttcatgg tagtatttag atggtcaagt gagtcaaaag aagtttcgac aagagcatac
    33901 cctttttcta ccagagtttt tagatgttta ggggcatcaa taccataagt gtactcaaag
    33961 tattttggaa accagatctt aagaaagctc gtaaagctag ccagttctct aaacgctaag
    34021 aactagctac aacacagcat ttacaacact tcatggttca caccatgggg tgttttttaa
    34081 tgattttaag caaaattcac acttaattga aagttattta aattagatga aaatttattt
    34141 tttgaaaaag tgggaaaaca ttgattctaa gcgaattttg aatcatattc gaatgggagt
    34201 ttttaaaatc atgtttcagt ggtaaaagta ccaaactgga ttctccatag taaaatgata
    34261 tctcctgcta gtgaatcatc tactaataag tccatatttc gcttgggaac gggcttggga
    34321 cttagaagcc aagtatccaa ctctcgttca ggcgatatga agggtttgac ttggtgttct
    34381 ttataaaatt tttctaaaat agtattcacg gatagcatct ttcaaacatt tatttcctat
    34441 tctaacaaat ttctaaatac tttaagaaat ttatagtctg tcaagttttt ttcttgacac
    34501 atgtcagaaa tctgctataa tagaacatgt gctaaatagc tcagctattt caccgaaata
    34561 aaaaattaaa gaaatgagac tttaaaaatg gcagttaaaa tccgtttgac tcgtatgggt
    34621 tctaagaaaa aacctttcta ccgtatcaac gtagcagatt cacgttcacc acgtgacgga
    34681 cgtttcatcg aaacagttgg aacttacaac ccacttgttg ctgaaaacca agtaactttg
    34741 aaagaagacc gcgttcttgc atggttggct aatggagctc aaccttcaga cacagtacgt
    34801 aacatccttt caaaagaagg cgtattgaaa aaattccacg attctaaatt ttcaaaataa
    34861 gtttaaagta ggttgacaga tggatacgat tgaaaatctc attattgcga ttgtgaaacc
    34921 cttaatttca caaccagatg ccttaactat caagattgag gatacaccag aatttttgga
    34981 atatcatttg aatcttgatc aaagcgatgt gggtcgtgta atcggtcgta agggtcgcac
    35041 tatttctgcg ataagaacga ttgtctactc tgtcccaact gaatacaaaa aagtaagaat
    35101 cgttattgac gaaaaataag aagggcggga cggatgtctc gcttttttgt gtggaataga
    35161 agatatagta aaatgaaaca agaacaggac aaatcgatca ggacagtcaa atcgatttct
    35221 aacaatgttt tagaagtaaa ggtgtactat tctagtttca atatactata aaagattgaa
    35281 cgtttaggca attccaagac tacttaatcg aacattaaca gcagtctcgg actgatgaag
    35341 gtctctttat gaagttagtg gaggaagtcg gaaaagtagc cgaggttttg aataggcgct
    35401 ctggtcgaaa agaagggata ggattcgaac gaggaacttg ccagagaact ggctgatatc
    35461 atttactaca ccgtcgcaat cgtagctatt aatcatattg accttaccaa gactgtcttt
    35521 gagaaagaca aaaccgcagc cgttaattac caacataaac ataatttgga aggattattg
    35581 aagggaaagt agagatgttg tccccttcct ccaacttgag aaaatccttg gaacgtgata
    35641 aaataaagga taatgatttt taataattca ttatatagaa tgagtggatt tctttatgaa
    35701 gaggtttgaa gtatctacag aaattggtag cctctctgtt acttatcaaa agcaaaagaa
    35761 agtgctagtt tgtctaaacg gagcaggttt gctaccaagt tatgaaaatt tttcacttat
    35821 acttgaaaaa cctcctccta caattggtta tttgacaatt gattttccga acacaggtag
    35881 gagtccgatt catgaccaag ctggaaaaaa tctagataat cttgcagatg cggtttatga
    35941 agtacttgaa gaattaggaa tttctgaata tatactttgt gcacatagtt ggagtggaat
    36001 tttagcttgc aaattactcg agaaaccaat taagcgtcag actttagtag caattgaacc
    36061 gacaactaaa aaagtcatgt ttgctgattt ttcagaaaat ccttatccaa aaatggaaga
    36121 gcagatgagg ctgattgacg agtgtggtcc tgaactttat tttaagaact taactcaagc
    36181 aacatttagt cctgaaacga ataaaaaaat ctgggaatta atgcaagaaa aaggcttaga
    36241 gttggaaaat caagatccag aatttcagat atctggagag attactgagg aagattttga
    36301 gaatttgtcg atagaatctc atgtccctgt ttttattttt tgtcagactt atagagaaaa
    36361 agagtacaga gaatcagaat attggacttc caatactaaa ctcattttag gagggaatca
    36421 ccattattta caatggtcag aatcggaaaa aattgcggct attattcgag aattgtcaga
    36481 ataagatgga aaaaaggaga ttacaggaga caagatgaac tactttaata ttgggaaaat
    36541 cgttaatacg cagggattac agggtgagat gcgagtcttg tctgtgacgg attttgcaga
    36601 agaacggttt aaaaaaggag ctgagctggc tttgtttgat gaaaaagatc agtttgtcca
    36661 aacagtgacc atcgctagcc accgtaaaca gaagaacttt gacattatta aattcaaaga
    36721 tatgtaccat atcaatacta tcgaaaagta caagggatac agtctcaagg tcgctgagga
    36781 agatttgaat gacctagacg atggtgaatt ttactatcac gagattatcg gtttggaagt
    36841 ctatgagggt gatagcttgg ttggaaccat caaggaaatc ctgcaaccag gtgctaatga
    36901 tgtctgggtg gtcaaacgaa aaggcaaacg tgatttgctt ttaccttata tcccaccagt
    36961 ggttctcaat gttgatattc caaataaacg ggtcgatgtg gaaatcttag aagggttaga
    37021 cgatgaagat tgatatttta accctctttc cagagatgtt ttctccactg gagcactcaa
    37081 tcgttggaaa ggctcgagaa aaagggctct tggatatcca gtatcataat tttcgagaaa
    37141 atgctgaaaa ggcccgtcat gtagatgatg atccctacgg aggcggtcag ggcatgttgc
    37201 tcagagcaca acctattttc gattcctttg atgctattga aaagaaaaat ccgcgcgtta
    37261 ttctccttga tcctgctgga aagcagtttg atcaggctta tgctgaagat ttggctcaag
    37321 aggaagagct aatctttatc tgtgggcact atgagggtta tgatgagcgc attaagacct
    37381 tggtaacaga tgagatttcc ctaggcgact atgtcctcac tggtggagaa ttggcagcta
    37441 tgaccatgat tgatgctaca gttcgcctga ttccagaagt gattggcaag gagtctagcc
    37501 accaagatga tagtttttct tcaggtcttt tagaatatcc tcagtacaca cgtccctatg
    37561 attatcgagg catggtcgtg ccagatgtat tgatgagtgg ccaccatgaa aagattcgtc
    37621 agtggcgatt gtacgagagt ttaaagaaaa cctacgagcg cagaccggat ttacttgaac
    37681 attatcaact gacagtagaa gaagaaaaaa tgctggcaga aatcaaagaa aacaaagaat
    37741 aaaggagaaa cctatgcaag taatcaaacg taatggcgaa attgctgaat ttaatccaga
    37801 taagatttac caagccatct tgaaggcagc ccaaactgtt tatgttttga cagatgattt
    37861 gcgtcaaaat cttgctcaag tcactaagaa ggtagttttg gatttacaag aagccaaggt
    37921 ggaacgtgcg actatcagta tgattcaatc tatggttgaa catcgtttat tgggcgcagg
    37981 ttacattacc attgcagaac actacatttc ctatcgttta caacgtgact tggaaagaag
    38041 tggttatgga gatcatatcg cagttcattt acattttgaa caaattcgct aagaaaaaag
    38101 agtgggatga agcaactaca tctcactctt tcttaaatct atttttttgg gctgtttgga
    38161 cagttgaggg gacaaatcgc aggcgttgaa tatcgcttat acggataatc cggctcacat
    38221 ttttggcaaa atttttcacg ataatttgct ggccttgctg atcatatttg atgatatcac
    38281 ctgtaaagct tgtctcagac aagataaggt gaacagcggt ttgtttctgg atagcctctt
    38341 caatagtggc tgtaagggag ttggtttcag tctggtcagg ttggtcatgt ccatttaaaa
    38401 aatcatgtat tttatctaga acttgctgga atttatgtct catattggcc tcccttcttc
    38461 tatatcaata ttatataaaa ttttcctaaa atctacaaga ttttacgaat aaactaatga
    38521 aactaaaaaa ggagaagaaa atggcagaat ttacatttga aatcgaagag cacttgttga
    38581 ctctttctga aaacgaaaaa ggttggacca aggaaattaa ccgtgtgagc tttaatggtg
    38641 cccctgcaaa gtttgatatt cgtgcttgga gtccagacca tactaaaatg ggcaaaggga
    38701 ttactctctc aaatgaagaa tttcaaacga tggtggatgc ctttaaaggc aactaatact
    38761 cttcgaaaat ctcttcaaac cgcatcagct ttgccttgcc gtatgtatgg ttactgactt
    38821 cgtcagtttc atccacaacc tcaaaacagt gttttgagca gcctgcggct agcttcctag
    38881 tttgctcttt gattttcatt gagtataagt tttcaaaata aaaaaaaagg atattgagtc
    38941 atgataactc gatatccttt tttagttagt aaagtaagcc tgatttttaa ggcgttgaag
    39001 taggggacgg ctaataaaac taatagccag aagtttgcca aggtctggaa tgataaaggg
    39061 aagaaccccc acaacaagag ctttttcaaa tgccattcca gctaggaaat gcaagctgag
    39121 aatcccgccg acaaagacaa gggcatcacc caagaggttt gcaagaaaaa tcttaacaac
    39181 accactcttg ctgttggtta gagaggaagt aagtccagag taaacgagat aaaaccaaag
    39241 atagcctgca gtagggccaa ctaaagcctg aaaaccagct ccacctcctg caaagacagg
    39301 aagaccgata gcacctagaa gaagatagag tccagcagaa agtacagcct ctctcggtct
    39361 aaagacagta gcaatcaagc cgattgcaaa gttttgcaga gtgaagggaa caggtccaat
    39421 tggaagactg atttgtgcca aaacagcaat gagagcagcc ccaatagcag ggatagcata
    39481 aacgtgagct tttttcaaaa tagttaacct cttttctaat gtatagtaac tattatactc
    39541 atataggagt cgatgtcaac cattttttaa aaacaaggta acaaaaactg taacagccga
    39601 ttttcgtgac tagtcaagtt ggataatttt tttgttgatt cgaaaattgt ctgtatagat
    39661 aatcctattt tattaataaa aaatatacta gtaaatactt gacaaattaa aaaataagtg
    39721 ttacattaaa aatgtaaacg gatacattta gatgtgttca attttaaaag gaggggtagt
    39781 tatgagatat tttaacgact ctagatacca taacggtgat taaaaaccta aatataatca
    39841 attcatatta aagtaatatg gagggactaa aaagagacta ttatttaatc ttcatcaaat
    39901 atttaaattc aaggagaagt aaaatgaaaa aaagaattaa taagaaagca tctgtttttc
    39961 tagttgcaag tgttttcagt tttagctttg ctactacagc tagtgtcgtt aacgcagtaa
    40021 cggcacaccc tgctccaagt cccattattg atgtatggga atatggtgta aatgataact
    40081 atggttattc gaattacttt gttagttctc caagtaatat tggatcaaaa tcttcagtaa
    40141 cgaatttttg gggaacagtt aaagctcagg ataaaaaaga ttatggatgg gcatattcaa
    40201 gtgcaacaaa atcttggaac gatgttcgct taaatgcata ttgggattat tatagatttt
    40261 aaaaataatt tatgaaaaca agagacccaa ttataagatt gggtctcttg taatatggta
    40321 attgcttatg aaattaaaat tatgtatcat tggattcttc ttttgtttga ttgctacaat
    40381 tggtctggtc actattagtg ataccgaaat ccccatacct ttaccaattg atggagcttt
    40441 ttctatccaa ggaaaaagta atctttctaa taacgaaata tacgaaatgg ttcgtgactt
    40501 atcaaaaacg gaaaaggtta ccatttacaa gccaatcgtt cagagttcgg gtcagttgaa
    40561 gtatgtaaat tttgatgatg taaataatga acaattaaag tcagcaccaa tagtagggat
    40621 gtattacaca cttgggaaaa tggatgtaga cagtttgaaa ccacttacga tgacgggact
    40681 acaaacagtc tatatggctt atccttggta tataggagga atattacaat tcactggaac
    40741 tttaagaata ctgttaatgg gttcaattta tttaacttta ttagttgttt tatttgttgt
    40801 taggacgagg cagatcaaag aaggagtgat acgacgttct ttgggcttgc ctatatacga
    40861 cttaagaaga gagtatggca tttctcttat ttttgaactg attatgatgg ctttattgat
    40921 gatttcttac agttcttttt tgggtaatgg tttcttcacc tatagttcta agttattttt
    40981 ctctctgctt ttaacgaatt ttatactatt tcaaatcatt gatcttatta cttttgtttt
    41041 attttggttg acgattcaga ttgaaaagcc tattgaaatt attaaaaaca aggcaaaaaa
    41101 caagcttatt tttgtcgtat ggcttgctat tatttcgatt atcatccttg tctcaggagt
    41161 ttttttacaa gaaacaaaga gtagtcaatc tagtattaac atacagatac agaatttagt
    41221 accatgggat acagtaaaag actggagaag gattgagttc cttggaattg aaagtaactc
    41281 tactaaaaat agagaagtta atgattcaga tggtcagtat ctacagatag ttgctgcctt
    41341 aaaaaactta gatttcttat atatagaacg gtcttcagca tatgttccag atttcatgaa
    41401 aacttcacat gttatagaaa atttttctaa acaattagaa aatgacggga taacgaatcc
    41461 agaaataaat aaagagttaa tttatatcaa ccaaacaggt gctaacctac aaaataaagt
    41521 gaatggaaca aactatcatc ttttagataa taagatagca accatctata ttcctgagaa
    41581 gtggaaagaa aaccagaaat ctattgagaa tacagttgta gcagaacaat ttattggaac
    41641 aaactataca agagaacagc ttgcagttca aataattcct gatggggaaa aaatttttta
    41701 ttttaatgag gatgctgata ataatcttaa aatgaaagat attttaccgc tggcaaatgt
    41761 agcagatagc aaagataata tagttgttgt gttagatacg gacaaaatga tggaaaataa
    41821 taagttttct ttggctagta acatactata taaatctctt tttagtcctg aagcggtaaa
    41881 aaaaataaat gagatgactg tcctgttgaa tttctcaatg aatccagtag atgtttacca
    41941 aattgtgaaa ttaaagattc aatccttaga gcaccaaatt ttactttcac aaatcttgca
    42001 gaagataatt tacagtattg tctttatact catttatcaa tatgtccaac tttttattac
    42061 tctaaaacag aatgaatatg tgaaaaaaat cattttgggt ctgtcaaaaa catatatagc
    42121 aatttcaagt ctcaaatatt ttatgatgac tattacaatg gttattctat ttacatttct
    42181 tatgacaggg caaatagagt tgctatatat tggagcggct tctctgctag ttttgatgtt
    42241 gtcaatcata atgagtttta gaaaattatc tgaaagctac actaaaattt taaaaggaga
    42301 tgaatcatga caattgacct tttgaacgtt tcaaaaagtt tcggctcaaa gaagatcttt
    42361 acagacttaa atttaatatt tgaatctgga aaaagctatg cattgattgg aggttctggc
    42421 tccggtaaaa gtacccttct taatattata ggaagattag aaaaaattga cagtgggaat
    42481 gttttagttg ataaacaaga tatttggaag ataaaagaaa gaactttttt taaaaatact
    42541 gttggatatg tatttcagaa ttattcttta atagataaca aaacagtgta tgataatctg
    42601 agccttatca ctaaagacaa aaaaacaata actgacgtac ttgaaaaagt aggactgtca
    42661 agtgactatt tacaccaaaa aatatatgaa ttgtctggag ggcaggctca acgtgtagct
    42721 attgccagaa tgttaatgaa accacgtaaa attatcttag cagatgaacc tacaggagct
    42781 ttagatggtg agattggaaa agaaattatt cgtttactat tgaatgaaac agctgaagat
    42841 aaatatgtca ttatagcgac acatgatcca gctgtctata acgaagttga tgtgataatt
    42901 gacatgaaag atatagggta taaggtatga aaaagaaaat ttatattgct ttgatctttg
    42961 taactggggt actcgccatt ttcttttttg gaaaacaaat gattacaaaa gaaaatatca
    43021 ataagccaac ggtagagtta acaatctata cgctttcttc tagtgataca gaaaaatgga
    43081 ataaagtgag acaagtagaa acggaagaag ctatatactt cataactgtg aaagaagtat
    43141 catcttcaga agaagtattt tcaaacatca ttgcaaatgg agctgctacg gggttcggag
    43201 ttcgtgaaga agaagtgaag aaattcaata atggtttagg agacaccata gaggactcta
    43261 agcataataa actaattgaa atagaatttt ttactttttc tgatgatggc gcgggatttg
    43321 tggtagcaaa ctttgactac ggtaaagaag agttgaattc tcagaaaaaa gatataaaag
    43381 aattatataa aaaaatatat gaatctttta aagaaaagaa taaatgattg tattataatc
    43441 cttgtatttt gctatggttt gttaattgat ttttgcatat cttacttcaa catactataa
    43501 aataaaacat aagaaaacga gtatctccaa ctacggaaat actcgctttt tgatatttag
    43561 aagtgttttt tgctttgctt cttttgtttc gattaacgca tggttacaaa ttcttcagat
    43621 gcagttgggt gaattgccac agttgcatca aagtcagcct tggttgctcc cattttgata
    43681 gcaacggcaa atccttgaat catttcatca acgccgtagc caattccatg aagtccgaca
    43741 actttttctt ctgaaccagc tgttatgagt ttgaaacggg attcttgacg gttgcgagtg
    43801 caagcagagt acatagatgc aaagcttgat ttataaacct tgatttggtc ttgaccgtat
    43861 tctttaatag cttgctcttc tgtcaaacca acagttccga tagcagggtg tgaaaagaca
    43921 acagttggaa tagttgagta atccattttt gcagtagttt ttccgttaaa gagacgttca
    43981 gatagggtac gtccggcctt gattgcaact ggagtcagtt ctttctcgcc cgttacatca
    44041 cctagagcat agattccctc aacaacagta ttttggtatt catccacttg gataaagcca
    44101 cgttcgttca gagtcactcc agctttttca agttgcaagc ccttaacgtt tggacggcga
    44161 cctgtagccc agataacttg gctagctgtg tgactagtac catcttcgaa atgaatggta
    44221 atgccgtcag tagttttttc taacttgaca gggactttgt gagtgtgaag tggtaagttt
    44281 gttctttcca tttccttgac caaaccttca acgatgtagg aatcaaaacc acgtaaagga
    44341 cgatcgcggc gaacaaagag atctgtcttg acaccaaaag tgtggagtac gccagctaat
    44401 tcaacggcga tataaccagc gcctagaatg gcaattgact ctggaagttc ttcccaggca
    44461 aatacatcat cagaagagcc acctagctca gcaccaggaa tattaggaat acttggatgg
    44521 gcacctgtag caatcacgat atgtttagca cgaatcagtt caccatttac gcttacagta
    44581 tgagaatcta caaattcagc atgaccttca atcaagtcta caccgttgcg tttaaaacta
    44641 ccatcataag aagaacgagc gcgatcaatg taggcttcac gattgcgacg tagggttgca
    44701 aagtcaaagt taagatcagt agtcttaaag ccgtagtctt ctccaaattg atggaaagtc
    44761 tcagcgattt gcgccccgta ccacatgatt tttttaggaa cacaaccgac gttgacacag
    44821 gttccaccta atttcttttc ctcaataacg gctgctttgg ctccatgttc accagcacgg
    44881 ttcatggtag cgattcctcc gctacctcca ccgatagcaa tgatatcata ttctctcatt
    44941 gaaaactcct ttgtaatctt ttaaatagta gagcgtcttt tttgatagtt atattttatt
    45001 ctttttttga tttgattgca aaaatctgct acgcacaaaa aattgcaaaa aagcttgcca
    45061 aataagtcaa gatagtgtat tatatatcta gtacaataga aaagcaaaat tccgaacgat
    45121 tgtttaatcc tgaactgtat tgtttgctgg agggaaattt ggtataatag caaagtattg
    45181 taaaaaagaa aaggagtttc attatgaaga aaaagaatgg taaagctaaa aagtggcaac
    45241 tgtatgcagc aatcggtgct gcgagtgtag ttgtattggg tgctgggggg attttactct
    45301 ttagacaacc ttctcagact gctctaaaag atgagcctac tcatcttgtt gttgccaagg
    45361 aaggaagcgt ggcctcctct gttttattgt cagggacagt aacagcaaaa aatgaacaat
    45421 atgtttattt tgatgctagt aagggtgatt tagatgaaat ccttgtttct gtgggcgata
    45481 aggtcagcga agggcaggct ttagtcaagt acagtagttc agaagcgcag gcggcctatg
    45541 attcagctag tcgagcagta gctaaggcag atcgtcatat caatgaactc aatcaagcac
    45601 gaaatgaagc cgcttcagct ccggctccac agttaccagc gccagtagga ggagaagatg
    45661 caacggtgca aagcccaact ccagtggctg gaaattctgt tgcttctatt gacgctcaat
    45721 tgggtgatgc ccgtgatgcg cgtgcagatg ctgcagcgca attaagcaag gctcaaagtc
    45781 aattggatgc aacaactgtt ctcagtaccc tagagggaac tgtagtcgaa gtcaatagca
    45841 atgtttctaa atctccaaca ggggcgagcc aagttatggt tcatattgtc agcaatgaaa
    45901 atttacaagt caagggagaa ttgtctgagt acaatctagc caacctttct gtaggtcaag
    45961 aagtaagctt tacttctaaa gtgtatcctg ataaaaaatg gactgggaaa ttaagctata
    46021 tttctgacta tcctaaaaac aatggtgaag cagctagtcc agcagccggg aataatacag
    46081 gttctaaata cccttatact attgatgtga caggcgaggt tggtgatttg aaacagggtt
    46141 tttctgtcaa cattgaggtt aaaagcaaaa ctaaggctat tcttgttcct gttagcagtc
    46201 tagtaatgga tgatagtaaa aattatgtct ggattgtgga tgaacaacaa aaggctaaaa
    46261 aagttgaggt ttcattggga aatgctgacg cagaaaatca agaaatcact tctggtttaa
    46321 cgaatggtgc taaggtcatc agtaatccaa catcttcctt ggaagaagga aaagaggtga
    46381 aggctgatga agcaactaat tagtctaaaa aatatcttca gaagctaccg taatggtgac
    46441 caagaactgc aggttctcaa aaatatcaat ctagaagtga atgagggtga atttgtagcc
    46501 atcatgggac catctgggtc tggtaagtcc actctgatga atacgattgg catgttggat
    46561 acaccaacca gtggagaata ttatcttgaa ggtcaagaag tggctgggct tggtgaaaaa
    46621 caactggcta aggtccgtaa ccaacaaatc ggttttgtct ttcagcagtt ctttcttcta
    46681 tcgaagctca atgctctgca aaatgtagaa ttgcccttga tttacgcagg agtttcgtct
    46741 tcaaaacgtc gcaagttggc tgaggaatat ttagacaagg ttgaattgac agaacgtagt
    46801 caccatttac cttcagaatt atctggtggt caaaagcaac gtgtagccat tgcgcgtgcc
    46861 ttggtaaaca atccttctat tatcctagcg gatgaaccga caggagcctt ggataccaaa
    46921 acaggtaacc aaattatgca attattggtt gatttgaata aagaaggaaa aaccattatc
    46981 atggtaacgc atgagcctga gattgctgcc tatgctaaac gtcagattgt cattcgggat
    47041 ggggtcattt cgtctgacag tgctcagtta ggaaaggagg aaaactaaga tgcagaatct
    47101 gaaatttgcc ttttcatcta tcatggctca caagatgcgt tctttgctta ctatgattgg
    47161 gattattatc ggtgtttcat cagttgttgt gattatggct ttgggtgatt ccctatctcg
    47221 tcaagtcaat aaagatatga ctaaatctca gaaaaatatt agcgtctttt tctctcctaa
    47281 aaaaagtaaa gatggttctt ttactcagaa acaatcatct tttacggttt ctggaaagga
    47341 agaggaaatt cctgttgaac cgccaaaacc gcaagaatcc tgggtccaag aggcagctaa
    47401 actgaaggga gtggatagtt actatgtaac caattcaacg aatgccatct tgacctatca
    47461 agataaaaag gttgagaatg ctaatttgac aggtggaaac agaacttaca tggacgctgt
    47521 taagaatgaa attattgcag gtcgtagtct gagagagcaa gatttcaaag agtttgcaag
    47581 tgttattttg ctagatgagg aattgtccat tagtttattt gaatctcctc aagaggctat
    47641 taacaaggtt gtagaagtca atggatttag ttaccgggtc attggggttt atactagtcc
    47701 ggaggctaaa aggtcaaaaa tatatgggtt tggtggcttg cctattacta ccaatatctc
    47761 ccttgctgcg aattttaata tagatgaaat agctagtatt gtctttcgag tgaatgatac
    47821 cagtttaacc ccaactctgg gtccagaact ggcacgaaaa atgacagagc ttgcaggctt
    47881 acaacaggga gaataccagg tggcagatga gtccgttgta tttgcagaaa ttcaacaatc
    47941 gtttagtttt atgacgacga ttattagttc catcgcaggg atttctctct ttgttggagg
    48001 aactggtgtc atgaacatca tgctggtttc ggtgacagag cgcactcgtg agattggtct
    48061 tcgtaaggct ttgggcgcaa cacgtgccaa tattttaatt cagtttttga ttgaatccat
    48121 gattttgacc ttgttaggtg gcttaattgg cttgacaatt gcaagtggtt taactgcctt
    48181 agcaggtttg ttactgcaag gtttaataga aggtatagaa gttggagtat caatcccagt
    48241 tgccctattt agtcttgcag tttcggctag tgttggtatg atttttggag tcttgccagc
    48301 caacaaggca tcgaaacttg atccaattga agcccttcgt tatgaatgag atcaacaaga
    48361 tggacactcg tctatcttgt ttttgtatgg atttccctat cgaaattcat taaaaatgtg
    48421 atataatgaa gtgttagaaa aacaggtttc atttgcctgg aaaggaaaaa ttatgtctga
    48481 aaaaaatttt tatattacaa cgccgattta ctatccatct gggaaacttc atatcggttc
    48541 tgcctacaca actatcgcat gtgatgtcct agcacgttac aaacgcctga tgggctacga
    48601 tgtattttat ctgacaggtc ttgatgaaca tggtcagaaa atccagcaga aagcggaaga
    48661 agctggtatt acacctcaag cctatgttga tggaatggcg gttggagtta aagaactctg
    48721 gcaattacta gatatctcat acgataaatt tatccgtaca actgatgact accatgaaaa
    48781 agttgtcgca caagtctttg aacgcttact tgctcaagat gatatctact tgggtgaata
    48841 ctctggttgg tattcagtat cagacgaaga attctttaca gaaagccagc tggcagaagt
    48901 tttccgtgat gaagctggaa atgtgactgg tggtattgct ccatcaggtc atgaggttga
    48961 atgggtttct gaagaatcat acttccttcg ccttagcaaa taccaagacc gtttggtcga
    49021 atttttcaaa gctcatcctg aatttatcac gccagatggt cgccttaatg aaatgctacg
    49081 caacttcatc gagccaggtt tggaagattt ggcggtatct cgtacaacct ttacatgggg
    49141 agtgcctgtc ccatcaaatc caaaacacgt tgtctacgtt tggattgatg cccttcttaa
    49201 ctatgcgaca gctcttggct acgctcaaga cgaacatggt aactttgaca agttctggaa
    49261 tggaacagtc ttccatatgg taggaaaaga tatccttcgc ttccactcta tctactggcc
    49321 aatccttctt atgatgttgg atgttaaatt acctgatcgt ttgattgccc atggttggtt
    49381 tgtcatgaaa gacggaaaaa tgtctaagtc aaaagggaat gtcgtttacc ctgaaatgtt
    49441 ggtagagcgt tatggactag atccacttcg ttactacctc atgcgtaacc ttccagttgg
    49501 ttcagacgga acctttactc ctgaagacta tgtcggccgt atcaactatg aattggctaa
    49561 tgaccttggg aacctcctta accgtacggt ttccatgatt aataagtact ttgatggaca
    49621 aatccctgcc tatgtagaag gtgtgactga atttgatcat gttcttgctg aggttgcaga
    49681 acaatcaatc gcagacttcc atacacacat ggaagcagtt gactatccac gtgcgcttga
    49741 agcagtctgg actctgatct ctcgtaccaa taaatacatc gatgagactg caccatgggt
    49801 cttggccaag gatgaagctc ttcgtgacca attggcaagt gtcatgagcc acttggcagc
    49861 cagcattcgt gtagttgctc acttgattga accatttatg atggaaacta gtcgtgcagt
    49921 tttgactcaa cttggtttgg aagaagtttc tagtcttgaa aacttgagtt tggctgactt
    49981 cccagcagat gtgactgtag ttgccaaagg aacacctatc tttccacgtc taaatatgga
    50041 agaagaaatc gcctatatca aggaacaaat ggaaggcaat aaaccagcag tcgaaaaaga
    50101 atggaatccg gacgaagttg agctcaaact aaacaaggat gaaatcaagt ttgaagactt
    50161 tgacaaggtt gaaatccgtg tcgcagaagt caaagaagtg tctaaagtag aaggttcaga
    50221 taagttgctt caattccgct tggatgctgg tgatggagaa gatcgtcaga ttctttcagg
    50281 aattgcaaaa tactatccaa atgaacaaga attggtcggc aagaaagttc aaatcattgc
    50341 taacctcaaa ccacgtaaaa tgatgaaaaa atatgtcagc cagggtatga ttctctcagc
    50401 tgaacatgat ggcaaattaa cccttctcac agttgatcca gctgtaccaa atggaagtgt
    50461 gattgggtaa aagtagacag gactagttca ggctagttct gtttttttat ttatactcaa
    50521 tgaaaatcaa agagcaaact aggaagctag ccgcaggttg ctcaaaacac agttttgagg
    50581 ttgtagatga aactgacgaa gtcagctcaa aacacagttt tgaggttgta gatgaaactg
    50641 acgaagtcag taaccataca taaggtaggg cgacgctgac gtggtttgaa gagattttcg
    50701 aagagtatta actattatgc tttacaaact agtgtagaag tgatatacta taggtgaagt
    50761 tactagtagg tattacaaaa tagattagaa gggaaaagtg atgaaagaaa ctcagctatt
    50821 aaaaggtgtt cttgaaggtt gtgtcttgga tatgattggt caaaaagagc ggtatggtta
    50881 tgagttggtt cagactttgc gagaggctgg atttgatact atcgttccag gaactattta
    50941 tcctttgttg caaaagttag aaaaaaatca atggataaga ggcgacatgc gcccgtcgcc
    51001 agatggtcca gatcggaagt atttttcatt aatgaaagaa ggagaagagc gtgtctcagt
    51061 cttttggcaa caatgggacg atttgagtca aaaagtagaa gggattaaga atgggggtta
    51121 aaccatgaag aaaatgaagt attacgaaga aacaagcgct ttgctacatg agttttctga
    51181 ggagaatcaa aagtattttg aggagttgtg ggaaagtttt aatcttgctg gatttctcta
    51241 tgatgaagac tatctcagag agcagatcta tttgatgatg ctagatttct cagaagcaga
    51301 acgagatggc atgagtgcag aggattatct aggtaagaat cctaaaaaaa taatgaaaga
    51361 gattctcaag ggagcacctc gcagttctat caaagagtcc cttttgacgc caattcttgt
    51421 cctggcggta ttacgttatt atcaactact aagtgatttt tctaaaggtc ctctattaac
    51481 agtcaatttg ctcacatttt tagggcaact tcttattttt ctgattggat ttggacttgt
    51541 ggccacaatt ttacgaagaa gtttagtcca agattctcct aaaatgaaaa ttggcactta
    51601 cattgttgtt gggactatag ttcttctagt tgttttagga tatgtaggaa tggcaagctt
    51661 catacaagaa ggagtctttt atattccggc tccctgggat agtttgtctg tctttacgat
    51721 ttcgctagtt atcggtattt ggaattggaa agaagcggtc tttcgtccat ttgtcagtat
    51781 gattattgcc catcttgtgg tgggttctct gctccgttat tatgagtgga tgggaatttc
    51841 aaatgttttc cttacaaaag ttattccttt agctgtcctc tttattggaa tctttgtctt
    51901 gttccgtggg tttaagaaga taaaatggag tgaagtatag tcaaaaagcc gttgcaaagc
    51961 ggttttttgt tataatgaag ggaagaatgt tagaaattaa aggagaaaaa tttgatgaga
    52021 tacataactc ttggtcaaga tgacaaagaa ttatcagaaa ttgttctcgg aatgatgaga
    52081 ataaaagata aatctgtaaa agaagttgaa gagcttgtag aaacagcact ttctgttgga
    52141 atcaatgcct tcgacttggc tgatatttat ggtcgtggtc gttgtgaaga actgttaggt
    52201 cttgtcctaa aaaatcgtcc agatttaaga gaaaagatgt ggattcagtc caaatgtggc
    52261 attcgcattg aagaatttac ctattttgat ttttctaagg actatattat aaaatcagta
    52321 gacggtattt tgcaaagatt gaagattgat catctagata gcttgctcct tcatcgacca
    52381 gatgctttga tggaatctga ccaagtagca gaagcctttg atctccttta taaacaaggt
    52441 aaagttcgag attttggagt ttctaatcaa aatcctatga tgatggagtt gcttaaaaaa
    52501 gatgtcaagc agccgttagc tgttaatcag ctacaattga gtgcggcttt tactccagga
    52561 tttgaatcag cttttcatgt taatatggaa gatagtcaag cagctatgcg agatggcagc
    52621 atttttgaat attgccaatt acacgatgtg gtcattcaag catggtctgt cttgcaattc
    52681 gggtatttta aagggaactt tgttggaaat gagaaatttc aagctttaaa tcaagtactt
    52741 gatcgtttag ctattaaata tggagtaacc tcttcaacta ttgccatttc ttggatattg
    52801 cgttatccag caaaaatgca ggcagtcgta ggtacaacaa atcctaagca cttgagagaa
    52861 gttagccgag cggcaaactt tagcttaaca agaaaagaat ggtatgaaat ttatcttgct
    52921 gcagggaata atttgccgta agtagtagca ggtttgaata actcacagtc aaaaagccgt
    52981 ataaagtggt tttttgctat aattaaatga agaatgtaga attaaaggag aaaaacatga
    53041 catttgaaga gatcctgcct gggttaaagg ctaagagaaa atatgtacga actggttggg
    53101 gaggtgcgga aaactatgtc caactctttg ataccatcga gcaaaatggg cttgcacttg
    53161 aaatgacacc ttatttccta atcaacgttt ctggagaagg agaaggtttt tccatgtgga
    53221 gcccgacagt ttgtgatgtt ttggcaacgg attgggtaga agtgcatgac taaacgtgta
    53281 ctcattacag gagtgagttc agggatcgga ttggctcaag ctcgcctctt tttagagaag
    53341 ggctatcaag tttatggagt tgaccaaggt gaaaagccac tcttagaggg tgattttcac
    53401 tttttacaga gagatttgac cttggacttg gaacctattt ttgactggtg ccctcaggtg
    53461 gatgttttgt gtaatactgc cggagttttg gatgcttaca aaccactgtt ggaacaaacg
    53521 gcgcaggaca ttcaagagat ttttgaaatc aactacatta ttccagtaga gttgactcgg
    53581 tattatttga cacaaatgct ggaaaataaa aagggaatca tcatcaatat gtgttccatt
    53641 gcttctagcc tagcaggtgg aggtggtcac gcctatactt catccaagca tgccttggct
    53701 ggcttcacca agcagttggc tctagactat gctgaagcta ggattcaggt ctttggtatc
    53761 gctccaggag cagtcaagac agctatgacc gctgcggatt ttgagacagg tggcttagct
    53821 gactgggtgg ctagtgaaac cccaatcaag cgctggattg aaccagagga agtggcagaa
    53881 gtcagtctct ttttggccag tggaaaggca tctgccatgc agggacaaat tctgacaata
    53941 gatggtggct ggtctttgaa gtaggaggag ttggatggaa atcaaaaatc actttggggt
    54001 ctactgtgtt tgctttgaaa atggaaagtt actttgcatt gaaaaaacga gaggccctta
    54061 tcaacatcgg tatgatctac ctggaggcag tcagcaactt ggtgaaggac tgacggaaac
    54121 gctgactaga gaagttatgg aagagacggg atttactgtt agaagctact ctaatcctcg
    54181 aatctacgat gttttcgtca gggaagagtt aaaaaatttt atggttcacc atgtcatagc
    54241 cttgtatgat gttgaaatga atgagagtgc acctcaagtt acgatttcgg aagctgtgtc
    54301 tgatggtgcg aatgattcac ttggatatat ttggatggat attcaagaga ttacagaaga
    54361 aaatgcatcg ccattagtct tgaaggttaa gtctgaatta ttaggattgc cagaactgga
    54421 caagacttct tacatgaatt ggaaggtgaa gtagagggat aatggaacta tttaaaacat
    54481 ggaagaaaaa tatggttctc tatggtctta aatctcaaat tggaactgtc taccgaaaca
    54541 atgataggac aacaagcttt tatgatgttg ggaattttct atacctagca ggggagttgg
    54601 attccagatt ttgggaagat tttgttagaa aatatggttt agattataag attattattt
    54661 cagaaaatac taattggcaa gattttctgc atcgaaaagt ggggctaaat tcttttactc
    54721 gctattcttt taaagataag gcaaattttc aagttgaatt tttaaataat ctagttactc
    54781 atttagagga aggttacaat attgtgccta ttgataatca tatttataac tgcttttcta
    54841 cggaagaatg gtcacaggat ttacaggggg attttgagtc ctatcaggat tttgttttaa
    54901 aaggtggatt tggctttgtg attcttaaaa ataatgaact gattgctggg atttcctcag
    54961 ggttagttta ccgtaaagca gttgaagtgg aagttgcaac tagaccaaac gaacaaggaa
    55021 atggatttgc taaaaagctt ggtgctgcaa tgattctaga gagtttaaat agagatatgt
    55081 ttccactttg ggatgctcat aatgaggctt ccaaaaaagt agcagaattt ttaggatatg
    55141 agttatctga accttatgaa gcttttgaac tagaggaaat tttgatataa ttatatatga
    55201 tattgtatct tttaagacga ggtgaatggc tatgagaaat caacttgccc ttagtggcga
    55261 aaaaattctt gaaaaaattt atcctcaact atttcaccac gtcggcatga ttcgtgggga
    55321 atatttgttg agagagctta atcaaaacat catattagca agttgtcagc aatttgtaaa
    55381 agattatcta gagactatct gctccctgta ctcagatgaa gaagtttggt atcgtttttc
    55441 tgaattaacg aatacagaag ccaattgttt agtggggact agagagtttt ttgacgaagg
    55501 gcatcccttg tttggctata gaggaaccag gcgtttactg gcgtgtttgg atgaatttca
    55561 ggctgaagca catgtcgtta cagaagttta tcaaaccaat cccaatctat ctcttatctt
    55621 tccttttgtc aatgatgccg accaattaaa acaagctatt acagtattgc gtcagcaggg
    55681 ttttactggg aaagtcggaa cgatgattga attaccgtca gcgtattttg acttatctag
    55741 tatactggaa acgggcattt caaagattgt agttggaatg aatgatttga cttcctttgt
    55801 ttttgcgact atgagaaaca gtcaatggca tgatatggaa agtccaataa tgttagatat
    55861 gctaagagat atgcaggata aagcaagaaa gaacaagatt gattttgctg tagcaggcta
    55921 tctgaatact tctttcatac aaaaaatgaa tcagttgggt atcaagtgca ttatccacta
    55981 cagttctatt ccagagattt ttgatttaga gattgaccat ccagatcatc ttaaacacat
    56041 aaaagaagaa agtaaaaaat tacaaaggag tacccatgat accgcaagaa atgtggaata
    56101 aatacaagca aatcaatcct ttgatcggag atgaaatcga tgcttgggct tttggagttg
    56161 aaccagatct tttagcggat ttggtgttta aaggagaaaa gacagcaaca gcatcagcct
    56221 atgacctcta tgtactagaa gacgaaccac ttccccaagt agggaccttc gatatcattt
    56281 tagatagtca aaatcagtct gtctgcattg tcgaaattac aaaggtttct gttgaactct
    56341 tcaatcaagt ttctgcgcaa catgccttta aggaaggtga gggagacaaa tcacttgcct
    56401 attggcgcca ggttcatgag gactttttca cagactgttt gggtgaagta gggctgactt
    56461 ttacacctga aagcaaggtt gttttagaag aatttcgcaa ggtctaccca ctgtagacta
    56521 ttagaaggaa gaaagttttg gaaatcgctg tccaatcctt ttttttcaag caaaatatga
    56581 tataataagt ttgtttgaag aagagcagca gctcttaaac ttagaatagg agaaaactat
    56641 gcaagcagtt gaacatttta ttaagcaatt tgttcctgaa cattatgatt tatttttaga
    56701 tttgagtcgt gagaccaaga ctttttctgg gaaagtgacc atcactggtc aagcacagag
    56761 tgaccgcatc tccctccacc aaaaagactt ggaaatcacc tctgtagaag ttgcaggtca
    56821 agctcgtcca tttacagttg accatgacaa tgaagccctt catatcgaat tggctgaggc
    56881 tggtcaagtt gaattggttc ttgccttttc tggtaaaatt acagacaaca tgacagggat
    56941 ttacccttct tattatacag ttgatggagt caagaaggag gtcttgtcta ctcagttcga
    57001 gagccatttt gcgcgcgaag ctttcccatg tgtggatgag cctgaagcca aagcaacttt
    57061 tgacctctct cttcgctttg accaagcaga aggtgaattg gccttgtcaa acatgccaga
    57121 aatcgatgtt gaaaaccgta aggaaacagg tatctggaag tttgagacaa cacctcgcat
    57181 gtcttcttac ttgttggcct ttgttgctgg tgatttgcaa ggggtgaccg ctaaaactaa
    57241 aaatggtacc ctggtaggtg tctactcaac caaagcacat ccactttcaa atcttgattt
    57301 ctcactggat atcgctgttc gctctatcga gttttacgaa gattactatg gagttaagta
    57361 tccaattcct caatctctcc acatcgccct tcctgacttc tcagctggtg ctatggaaaa
    57421 ctggggtctt gtgacctacc gtgaagttta cttggttgtc gatgagaact ctacatttgc
    57481 tagccgtcaa caagttgccc ttgttgtggc ccatgaattg gctcaccaat ggtttgggaa
    57541 cctcgtgact atgaaatggt gggatgacct ttggctcaat gaaagtttcg ctaatatgat
    57601 ggaatacgtc tgtgtggata ccatcgaacc aagctggaat atctttgaag atttccaaac
    57661 aggtggagta cctcttgctc ttgaacgtga cgctactgat ggcgttcagt ctgtccacgt
    57721 cgaagttaaa catccagatg aaatcaatac actctttgac ggcgctatcg tctatgccaa
    57781 aggaagccgt ctcatgcaca tgcttcgccg ttggctagga gatgctgatt ttgctaaagg
    57841 tttgcatgcc tactttgaaa aacaccaata cagcaacacc attggtagtg acctttggga
    57901 tgcccttggt caagcgtcag gacgtgatgt cgcagccttc atggattctt ggttggaaca
    57961 gcctggttac ccagttctta ctgtcaaagt tgaaaatgat gtcttgaaga tttcacaaaa
    58021 acaattcttc atcggtgaga acgaagacaa gaaccgtctc tgggtggtgc ccctcaatag
    58081 caactggaaa ggcttgcctg atacactcga aactgaaagt atcgaaatcc ctggctacgc
    58141 agctcttctt gctgaaaatg aaggagctct tcgtctcaac actgaaaata ctgcccacta
    58201 tattaccgac tatcaaggag acttgttaga agctgttctt gctgagctag agacacttga
    58261 taacacaagc aaactgcaaa ttgttcaaga acgtcgtttg ttggctgagg cagggcacat
    58321 ttcttatgca gacttgcttc cagttcttga taaacttgct aaggaagagt cttatctggt
    58381 ggtttcagct gtttctcaag tgatttcagc ccttgagcgc tttattgatg aaggaacgga
    58441 tgctgaaaca gccttcaaag gactggttgc taaattggct cgtcataact atgaccgtct
    58501 tggttttgaa gctaaagacg gagaatcaga tgaggatgaa ttggttcgtc agctggctgt
    58561 ttcgatgatg attcgctcaa atgatgcaga agctcgtcaa gtcgctagcc aaatcttcgc
    58621 aacacacaag gagaatcttg cagaactccc agcagctatt cgttcacaag ttctgattaa
    58681 tgagatgaaa catcatgaga ctaaagactt gttagcactt tatcttgata cttatactca
    58741 cgcaacagat gctgtcttta aacgccagtt ggcagcagct cttgcataca gtacagatgc
    58801 ggataatatc caaaacttga ttacttcttg gaaggacaaa tttgtggtca aaccacagga
    58861 cttgtctgct tggtattacc aattcctagc tcatcaagca actcagaaaa cagcttggtc
    58921 ttgggcgcgt gaaaactggg cttggattaa ggcagccctt ggaggagata tgagctttga
    58981 tagctttgtt atccttcctg ctcatgtatt taagactcag caacgcttgg cggaatacaa
    59041 ggagttcttt gagccgcaac tttctgacct tgctcttagc cgtaacatcg gtatgggaat
    59101 caaggaaatt gcagcacgtg ttgacttgat tagccgtgaa aaagctgcag tcgaagcagt
    59161 tgttcttcaa tacggaaatg cataaataag cctaaaataa aaa
//
LOCUS       DBEJJV010000009        52924 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.009, whole genome shotgun sequence.
ACCESSION   DBEJJV010000009 DBEJJV010000000
VERSION     DBEJJV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 52924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52924
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.009"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..304)
                     /locus_tag="ACL3GT_000627"
                     /pseudo
     CDS             complement(1..304)
                     /locus_tag="ACL3GT_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389597.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
     gene            473..1015
                     /locus_tag="ACL3GT_000628"
     CDS             473..1015
                     /locus_tag="ACL3GT_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HGR0516331.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            1015..1644
                     /gene="nth"
                     /locus_tag="ACL3GT_000629"
     CDS             1015..1644
                     /gene="nth"
                     /locus_tag="ACL3GT_000629"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HGR0516332.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            1855..2376
                     /gene="pyrR"
                     /locus_tag="ACL3GT_000630"
     CDS             1855..2376
                     /gene="pyrR"
                     /locus_tag="ACL3GT_000630"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HGR0516333.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            2395..3318
                     /locus_tag="ACL3GT_000631"
     CDS             2395..3318
                     /locus_tag="ACL3GT_000631"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HGR0516334.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            3368..4447
                     /locus_tag="ACL3GT_000632"
     CDS             3368..4447
                     /locus_tag="ACL3GT_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HGR0516335.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            4759..7935
                     /gene="carB"
                     /locus_tag="ACL3GT_000633"
     CDS             4759..7935
                     /gene="carB"
                     /locus_tag="ACL3GT_000633"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HGR0516336.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(8210..9019)
                     /locus_tag="ACL3GT_000634"
     CDS             complement(8210..9019)
                     /locus_tag="ACL3GT_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0516337.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(9021..9824)
                     /locus_tag="ACL3GT_000635"
     CDS             complement(9021..9824)
                     /locus_tag="ACL3GT_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HGR0516338.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYELLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(9834..11321)
                     /gene="tacF"
                     /locus_tag="ACL3GT_000636"
     CDS             complement(9834..11321)
                     /gene="tacF"
                     /locus_tag="ACL3GT_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HGR0516339.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIIKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNRIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIILLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            11657..12364
                     /locus_tag="ACL3GT_000637"
     CDS             11657..12364
                     /locus_tag="ACL3GT_000637"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050518 - 2-C-methyl-D-erythritol
                     4-phosphate cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HGR0516340.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            12369..13391
                     /locus_tag="ACL3GT_000638"
     CDS             12369..13391
                     /locus_tag="ACL3GT_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribitol-5-phosphate dehydrogenase"
                     /protein_id="HGR0516341.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            13408..14277
                     /gene="licA"
                     /locus_tag="ACL3GT_000639"
     CDS             13408..14277
                     /gene="licA"
                     /locus_tag="ACL3GT_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HGR0516342.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            14267..15145
                     /locus_tag="ACL3GT_000640"
     CDS             14267..15145
                     /locus_tag="ACL3GT_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0516343.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            15157..15846
                     /locus_tag="ACL3GT_000641"
     CDS             15157..15846
                     /locus_tag="ACL3GT_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HGR0516344.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYVSGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            15942..16790
                     /gene="dprA"
                     /locus_tag="ACL3GT_000642"
     CDS             15942..16790
                     /gene="dprA"
                     /locus_tag="ACL3GT_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HGR0516345.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(16974..17096)
                     /locus_tag="ACL3GT_000643"
     CDS             complement(16974..17096)
                     /locus_tag="ACL3GT_000643"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516346.1"
                     /translation="MKIKAQTRKLATGCSKHCFEVVDKTDEVSSKYCFEVADGS"
     gene            17679..18722
                     /locus_tag="ACL3GT_000644"
     CDS             17679..18722
                     /locus_tag="ACL3GT_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HGR0516347.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            18889..20976
                     /gene="topA"
                     /locus_tag="ACL3GT_000645"
     CDS             18889..20976
                     /gene="topA"
                     /locus_tag="ACL3GT_000645"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HGR0516348.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            21082..21441
                     /locus_tag="ACL3GT_000646"
     CDS             21082..21441
                     /locus_tag="ACL3GT_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HGR0516349.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            21534..22166
                     /locus_tag="ACL3GT_000647"
     CDS             21534..22166
                     /locus_tag="ACL3GT_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HGR0516350.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            22210..22866
                     /locus_tag="ACL3GT_000648"
     CDS             22210..22866
                     /locus_tag="ACL3GT_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HGR0516351.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            22936..23979
                     /locus_tag="ACL3GT_000649"
                     /pseudo
     CDS             22936..23979
                     /locus_tag="ACL3GT_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261078.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-isopropylmalate synthase regulatory
                     domain-containing protein"
     gene            23991..25028
                     /gene="leuB"
                     /locus_tag="ACL3GT_000650"
                     /pseudo
     CDS             23991..25028
                     /gene="leuB"
                     /locus_tag="ACL3GT_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            25025..25294
                     /locus_tag="ACL3GT_000651"
     CDS             25025..25294
                     /locus_tag="ACL3GT_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HGR0516352.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            25298..25657
                     /gene="leuD"
                     /locus_tag="ACL3GT_000652"
     CDS             25298..25657
                     /gene="leuD"
                     /locus_tag="ACL3GT_000652"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA];
                     GO_function: GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HGR0516353.1"
                     /translation="MAGSSREHAAWVLADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            25819..26442
                     /locus_tag="ACL3GT_000653"
                     /pseudo
     CDS             25819..26442
                     /locus_tag="ACL3GT_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004899133.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            26608..28539
                     /locus_tag="ACL3GT_000654"
     CDS             26608..28539
                     /locus_tag="ACL3GT_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HGR0516354.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSINSRQNLSVNYDSGVSGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            28526..29842
                     /locus_tag="ACL3GT_000655"
     CDS             28526..29842
                     /locus_tag="ACL3GT_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HGR0516355.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFFHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            30017..31003
                     /locus_tag="ACL3GT_000656"
     CDS             30017..31003
                     /locus_tag="ACL3GT_000656"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HGR0516356.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHNQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCVKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            31067..31138
                     /locus_tag="ACL3GT_000657"
     tRNA            31067..31138
                     /locus_tag="ACL3GT_000657"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31100..31102,aa:Arg,seq:ccg)
     gene            31321..32019
                     /gene="rnc"
                     /locus_tag="ACL3GT_000658"
     CDS             31321..32019
                     /gene="rnc"
                     /locus_tag="ACL3GT_000658"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HGR0516357.1"
                     /translation="MKELQTVLKNHFAIEFTDKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            32010..35549
                     /gene="smc"
                     /locus_tag="ACL3GT_000659"
     CDS             32010..35549
                     /gene="smc"
                     /locus_tag="ACL3GT_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HGR0516358.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSHQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDENAATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            35546..36340
                     /locus_tag="ACL3GT_000660"
     CDS             35546..36340
                     /locus_tag="ACL3GT_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0516359.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            36340..37158
                     /locus_tag="ACL3GT_000661"
     CDS             36340..37158
                     /locus_tag="ACL3GT_000661"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0516360.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            37162..38439
                     /gene="ftsY"
                     /locus_tag="ACL3GT_000662"
     CDS             37162..38439
                     /gene="ftsY"
                     /locus_tag="ACL3GT_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HGR0516361.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVIEVSQKEVKEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(38485..39972)
                     /gene="zwf"
                     /locus_tag="ACL3GT_000663"
     CDS             complement(38485..39972)
                     /gene="zwf"
                     /locus_tag="ACL3GT_000663"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HGR0516362.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWD
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRLE"
     gene            complement(40121..40861)
                     /locus_tag="ACL3GT_000664"
     CDS             complement(40121..40861)
                     /locus_tag="ACL3GT_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0516363.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(40861..43026)
                     /locus_tag="ACL3GT_000665"
     CDS             complement(40861..43026)
                     /locus_tag="ACL3GT_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HGR0516364.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            43199..44152
                     /locus_tag="ACL3GT_000666"
     CDS             43199..44152
                     /locus_tag="ACL3GT_000666"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamic
                     endopeptidase"
                     /protein_id="HGR0516365.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLQQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSSLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            44229..46217
                     /gene="uvrB"
                     /locus_tag="ACL3GT_000667"
     CDS             44229..46217
                     /gene="uvrB"
                     /locus_tag="ACL3GT_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HGR0516366.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            46227..46790
                     /locus_tag="ACL3GT_000668"
     CDS             46227..46790
                     /locus_tag="ACL3GT_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0516367.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            46756..47244
                     /locus_tag="ACL3GT_000669"
     CDS             46756..47244
                     /locus_tag="ACL3GT_000669"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0516368.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQMWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETMQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            47318..47785
                     /locus_tag="ACL3GT_000670"
     CDS             47318..47785
                     /locus_tag="ACL3GT_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HGR0516369.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGSLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(47782..48297)
                     /locus_tag="ACL3GT_000671"
     CDS             complement(47782..48297)
                     /locus_tag="ACL3GT_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HGR0516370.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(48309..48836)
                     /locus_tag="ACL3GT_000672"
     CDS             complement(48309..48836)
                     /locus_tag="ACL3GT_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0516371.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(49114..49677)
                     /locus_tag="ACL3GT_000673"
     CDS             complement(49114..49677)
                     /locus_tag="ACL3GT_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0516372.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(49661..50212)
                     /gene="coaC"
                     /locus_tag="ACL3GT_000674"
     CDS             complement(49661..50212)
                     /gene="coaC"
                     /locus_tag="ACL3GT_000674"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HGR0516373.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(50224..50913)
                     /gene="coaB"
                     /locus_tag="ACL3GT_000675"
     CDS             complement(50224..50913)
                     /gene="coaB"
                     /locus_tag="ACL3GT_000675"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004632 - phosphopantothenate--cysteine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HGR0516374.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            51143..52813
                     /locus_tag="ACL3GT_000676"
     CDS             51143..52813
                     /locus_tag="ACL3GT_000676"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HGR0516375.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIYVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
BASE COUNT        16264 a         9492 c        11560 g        15608 t
ORIGIN      
        1 acaggtccat agagacttag tacgtgtttg acatactcgt aatggatttt atcatagttt
       61 cgccaagcag tgcgtgcttg attgtttagt tttaggctac ccagtccaat cagaggactg
      121 gtgggttggt aaaatttctc aagattaatt aagatactgt tgttcaactt ttctgttttt
      181 tgagctcttg catagtagtg tttagcagct cttgtagtcg aatatcatct gccgtaacct
      241 gtttacagtt ttggtagctt ttatttaact tggataggag ttgaatgagt ttcttgtctt
      301 ccatgtgagc atcctccttg atctgatgta ctctttccct atagtatagc actaaaaaat
      361 aaaactatca tagtaaatat gttaaaattt gaattttaat tacaaagttt ggtgtgctga
      421 tttgtagcct tttcatggta taatcaagag agtaaatctt tatggaggaa gtatgaaatt
      481 aaatattcaa gaaattcgta agcagtctga aggtttgaac tttgaacaaa cgttagattt
      541 agttgatgac ctgcgtgcac gtaatcaaga aattttagat gtaaaagata tccttgcagt
      601 tgggaaagta caatatgaag accgtatgta tttcttagat tatcaactat cttataccat
      661 tgttcttgct tcgagtcgca gtatggagcc agttgagtta gttgaatctt atccagtcac
      721 ggaagttttc atggaaggcg caactaacca gctagatcaa gaagttttag atgatgactt
      781 ggtcttgccc atcgaaaatg gggcgcttga ccttgctgag agtgtatcag acaatatcct
      841 gctaaacatt cctatcaagg tcttgacggc tgaagaagaa gctggtcaag gatttgtctc
      901 aggaaatgac tggcaaatca tgacagagga agaataccaa gctcaacaag cagtaaagaa
      961 agaagaaaac agtccttttg ctggcttaca aggactattt gacggagatg aataatggtc
     1021 ttgtcaaaaa aacgagcacg aaaggtgcta gaagaaatca ttgccctctt cccagatgcc
     1081 aagcctagtc ttgattttac caatcatttt gaactcctgg ttgcggtcat gttatcagcc
     1141 cagacgacag atgcagcggt aaataaggcc acaccaggtc tctttgttgc ctttccaaca
     1201 ccccaagcta tgtctgtagc gacagagagt gagattgctt cacatatttc tcgcttggga
     1261 ttgtatcgga ataaagctaa attccttaaa aaatgtgccc aacagttact agacgatttt
     1321 gatggtcaag tccctcagac acgtgaagaa ttggagagtt tggcaggtgt tggtcgcaag
     1381 acagccaatg ttgtcatgag tgtaggattt gggattccag cctttgcagt ggatactcat
     1441 gtggagcgta tttgcaaaca ccacgatatt gtcaaaaaat cagcgacgcc acttgaggtg
     1501 gaaaagcggg tcatggatat cttgccgcct gagcagtggt tagctgccca tcaggccatg
     1561 atttattttg gaagagccat ttgccatcca aaaaatccag agtgtgacca gtacccacaa
     1621 ttatatgatt ttagcaattt gtaagatgct acattgaaac tttttgcttg attttaagca
     1681 tgctttgtgc tatagtaaat gataactaaa tattccttta aacctgtccc gtgaggcagg
     1741 caaggagcgc gataaagtag aagggtgaag tctacactgt gtgcagtagg gctcgcttgg
     1801 ctataaattt caagtctcct tgtttaagga gacttttctt tttggaggtt tgtcatgaaa
     1861 acaaaagaag ttgtagacga attgaccgtc aaacgagcga ttacgcgtat tacttatgag
     1921 attatcgaac gcaacaaaga tttgaataag atcgtcttgg ctggtattaa aactcgtggt
     1981 gtctttattg cccaccgaat ccaagaacgt ttgaagcagt tagaaaatct ttcagttcct
     2041 gttgtggaat tggatactaa acctttccgt gatgatgtta aaagtggaga agatacttct
     2101 ttggtttctg tcgatgtgac agaccgcgaa gttatcttgg tggatgatgt gctctataca
     2161 ggtcgtacca tccgtgctgc tattgataat attgtcggtc atggtcgtcc tgcgcgtgtg
     2221 agtttagcag ttctagtcga tcgtggacat agagaattgc caatccgtcc agattacgtt
     2281 ggaaaaaata tcccaaccag tcgttctgaa gaaatcatcg tagagatgac agaacttgat
     2341 gaccaagaca gagttctgat tactgaagaa gcttagaaag ttaaaggagt agccatgtca
     2401 gaaaatcaac aagcattgaa ccatgtggtg tccatggaag acctcactgt cgatcaagta
     2461 atgaaattga tcaagcgagg aattgagttt aaaaatggag cccagcttcc ctatgaagac
     2521 catccgattg tttccaatct cttctttgag gattctacac ggacacataa gtcctttgaa
     2581 gtcgcagaga ttaaacttgg attggaacga cttgactttg atgtgaagac tagttcggtt
     2641 aataagggtg agacacttta tgacaccatt ttgactctgt ctgctttagg agtggatgtc
     2701 tgtgtgattc gccatccaga ggtcgactac tatagagaat tgattgctag tccaacgatt
     2761 acgacttcca tcatcaatgg tggagatggt tcgggccaac accctagcca gagcttgctt
     2821 gatttgatga ccatttatga ggaatttggc cactttgagg gtcttaaagt tgctattgca
     2881 ggtgacttgg atcactcacg cgttgccaaa tccaatatgc agattttgaa acgcttggga
     2941 gctgaactct ttttcgctgg acctgaggaa tggagaagtc aagagtttgc agactatgga
     3001 cagtttgtaa ccattgatga aatcattgat caggttgatg tcatgatgtt tctccgtgtg
     3061 caacacgaac gccatgatag tggagctgta ttttcaaaag aagactacca tgcccaacat
     3121 ggcttgactc aagaacgtta cgatcgtttg aaagaaacag caatcctcat gcacccagct
     3181 ccaatcaatc gtgatgtaga aatagcagac cacttggttg aagcaccaaa atcacggatt
     3241 gtccaacaaa tgaccaatgg tgtctttgtt cgaatggcaa tcttagaatc cgtactagcg
     3301 agtagaaacg ccaactaaaa cacaagacgt taaaagacgc cagtgagcgt ccacgagagg
     3361 tgaaaatatg acaaaaagaa ttctagtatt agaagatggc acagtttttg aaggcaaggc
     3421 cttcggagca gatattgatg taacaggcga aatcgtcttt aatacaggga tgaccggcta
     3481 ccaagaatcc attacagacc agtcttataa tggacaaatc ttgaccttta cttatccttt
     3541 ggtaggaaat tatggtatta atcgtgatga ttatgaatcc attattccaa cttgtaaggg
     3601 agtcgttgtt tttgaagaag cgcgtagagc tagcaactgg cgcaaccaaa tgaccttgga
     3661 tgaatttttg aaagccaaga aaattccagg gatttcagga attgatacgc gtgctcttac
     3721 caagattatc cgtaagcatg gtactatgcg tgcaaccttg acccatgttg gggacagtat
     3781 ggaccatgtg acggaccagc tccaagcaac agttttaccg acagacaata tcaaacaggt
     3841 ttctactaaa acgtcttatc cagctccagg agttggtttg agcgtggtgc tagtggactt
     3901 tggtctcaag cactcaatcc tacgtgaact ttctaaacgc aactgtaacg tgacagttgt
     3961 tccttattcg acaacggctg aagaaattct ccatctcaat cctgatggag ttatgttgtc
     4021 aaatggtcca ggtaacccag aagacgttcc acaagcactc gacatgattc gcggtgtaca
     4081 aggaaaaatt ccaatctttg gtatttgtat gggacaccaa ctctttgcaa tggcaaacgg
     4141 ggctaagacc tataagatga agtttggcca tcgtggattc aaccatgcgg tacgtgaaat
     4201 cgcaacagga cgagtagact tcaccagcca gaaccatggt tatgcagtca gccgcgagga
     4261 tttgccagag cacttgatta ttacccacga agaaatcaat gacaagtcag tggaaggtgt
     4321 gcgccacaga taccaacctg ctttctctgt tcaataccac ccagatgcag ctcctgggcc
     4381 acacgacgct agctacctat ttgacgagtt tatcgagatg atggaagttt ttaaacaatc
     4441 aaactaagaa cgagtaaaag ctcgtcggag aatttatgta actgaacacg gacggaaagc
     4501 tcagaattta gagaaaccaa cttggattgt caatccttcc ttgatttctt aaaattcaat
     4561 cgctttctat tcgtcctttg tatcttattt aatgtcgccc tgagaggcga cgaatagaaa
     4621 ggagaagata cattgttcgc ggaagtgaac acgccctaag aactgtgtga aaaagataaa
     4681 catcgtcttg acgctgaagg cgtctgcgcc gagtttccta ttttcactgt gttctttacg
     4741 ggctttgtat cataaactat gcctaaacgt actgatattc aaaaaattat ggtgattggt
     4801 tctggtccga ttattattgg tcaggctgct gagtttgact acgctgggac ccaggcttgc
     4861 ttgtcgttga aagaggaagg ttatgaggtt gttttggtta actcaaatcc tgcaaccatc
     4921 atgacggaca aggaaattgc tgacaaggtt tacattgaac cgattacact tgagtttgtg
     4981 acacgtattc ttcgtaagga acgtccagat gccttgctac caacactcgg tggtcagaca
     5041 ggtctcaaca tggccatgga attatctaaa aatggtatcc tagacgagct tggcgttgaa
     5101 cttctgggta ccaaattatc tgccattgac caagcggagg accgtgacct ctttaaacaa
     5161 ttgatggaag agcttgagca acccattcca gaatctgaaa ttgttaacac agtagaagaa
     5221 gcagttgcct ttgcagcgac aattggctac ccagtcatcg ttcgtccagc ctttaccctt
     5281 ggtggtactg gtggtggtat gtgtgccaac gaaaaagaat tgcgtgaaat cactgaaaat
     5341 ggtttgaaat tgtcacctgt tacccaatgt ttgattgagc gttcgattgc cggttttaag
     5401 gaaattgaat acgaagtgat gcgtgactca gctgacaatg ccttggttgt ttgtaacatg
     5461 gaaaactttg acccagttgg gattcacaca ggggattcca ttgtatttgc ccctgcgcaa
     5521 accatgtcag actatgaaaa ccaaatgctt cgtgatgcga gcttgagcat tattcgcgcc
     5581 ctcaagattg aaggtggatg taatgttcag ctagctcttg atcctaacag cttcaagtat
     5641 tatgttatcg aagtaaaccc tcgtgtatca cgttcgtcag cccttgcttc taaagcgaca
     5701 ggatatccga ttgctaagtt ggctgccaag attgcagtag gtttgacctt ggatgaggtt
     5761 ataaacccag ttacaggttc aacctatgcc atgtttgaac cagcccttga ctacgtagtt
     5821 gctaagattc cacgtttccc atttgacaag tttgaaaagg gtgaacgccg tctcggtaca
     5881 caaatgaagg cgactggaga agtcatggca atcggtcgta acatcgagga atctcttctc
     5941 aaggcctgcc gctcccttga aattggggtg caccacaatg aaatacctga acttgcagca
     6001 gtttctgatg atgccttgat tgaaaaggtt gtcaaagccc aagatgaccg tctcttctac
     6061 gtatcagaag ccattcgtcg tggctacaca cctgaagaaa ttgcagagct tacaaaaatt
     6121 gatatcttct atcttgataa actcttgcat atctttgaaa ttgagcaaga attgggtgct
     6181 catccacaag atctagaagt tttgaaaaca gccaaactta atggtttctc agaccgtaag
     6241 attgctgaac tctggggaac gactgatgat caagttcgcc aacttcgctt ggaaaacaag
     6301 attgttccag tttataagat ggtagatact tgtgcggcag agttcgactc tgaaacgcca
     6361 tatttctatt caacctatgg ttgggaaaat gaatctatca gatctgataa agaatctgta
     6421 cttgtcctag gttcaggtcc aatccgtatc ggtcaagggg ttgagtttga ctacgcaacc
     6481 gttcactctg ttaaggctat ccaggcagct ggttatgaag ctatcatcat gaactcaaac
     6541 ccagagaccg tttcaacaga cttctctgta tcagataagc tttactttga gccattgaca
     6601 ttcgaagatg ttatgaacgt cattgacttg gaacaaccaa agggagttat cgttcagttt
     6661 ggtggtcaaa cagccatcaa ccttgcggag ccattggcaa aagcaggtgt gaccatcctt
     6721 ggtacacagg ttgctgacct agaccgtgcc gaagaccgtg acctcttcga gcaagctctc
     6781 aaagaattgg atattccaca gccaccagga caaacggcta ccaatgaaga agaagcagct
     6841 cttgcagctc gtaagattgg cttcccagtt cttgtccgcc catcttatgt acttggtgga
     6901 cgtgccatgg aaatcgttga aaacgaagaa gaccttcgtt cttacatgcg aactgctgtt
     6961 aaggctagtc cagatcaccc agttcttgtc gactcttata tcgttgggca agagtgcgaa
     7021 gttgatgcca tttcagatgg taaagatgtg ctcattcctg gtatcatgga gcatatcgaa
     7081 cgtgctggtg tccactcagg tgactcaatg gctgtttacc caccacaaac cttgtcgcaa
     7141 aaggttcagg agaccatcgc agactacacc aaacgcttag caatcggtct tcactgcctt
     7201 ggaatgatga acatccagtt tgttatcaag gatgaaaaag tctacgttat tgaggtcaat
     7261 ccacgtgcca gccgtactgt tccattccta tctaaggtaa ccaatattcc tatggctcaa
     7321 gtagcgacca agctcattct tggtcaaagt ttatcagaac ttggctacca aaatggactt
     7381 taccctgaaa gcacccgtgt tcatatcaag gcacctgtct tctcctttac caaactagct
     7441 aaggtagaca gcttgctcgg tcctgaaatg aagtcaacag gtgaagttat gggttctgat
     7501 gctactttgg aaaaagctct ctataaagcc tttgaagctt cttatctaca cttgccaact
     7561 tttggtaatg tcgtctttac catcgctgat gatgccaaag aagaagcctt gaacttggct
     7621 cgtcgtttcc aaaacattgg ttatggaatc cttgcgacag aagggacagc agccttcttt
     7681 gctagtcatg gcttgcaagc ccaacctgtt ggtaagattg gtgatgacga taaggatatc
     7741 ccaagttttg tacgcaaagg aagaattcaa gctatcatta acacagtagg aacaaaacga
     7801 actgctgacg aagatggtga gcaaattcgt cgttcagcca ttgaacacgg ggtgcccctc
     7861 ttcacagcgc tagatacagc taatgccatg cttaaggtac ttgaaagtcg tagctttgtt
     7921 acagaagcga tttaaataga aaaataagat atagcagact gaatttagaa cagtacacag
     7981 gaatactaaa atatttctat aaattaattt gaattttcta attgatttgt tcgcatctta
     8041 tttcaatcta ctatagaaaa aagtctttaa aattataaaa cgcatcatat caaggttttt
     8101 caaaaacctt gatatgatgc gttttattgt gggaatatgt atttcatttt ctactaaaat
     8161 tatgtttttg aataacctct atcttagtag tttgtataat ccccctcaat cagtttttgc
     8221 gataagcttt aatgctatga ctataccact cttgcatttc ttttgatggt ggtgtcatat
     8281 aatcgccata catctgggtt aaaaattggt catatttttt gggaacaggc aacatacggc
     8341 cctcaaactc agttaaaatc agttctttaa aggtatcaac tgggaagatt tctttcatcc
     8401 cttccttacc gatcccaact cctccttcat attgaggaat gttggttaca gcatttttga
     8461 ctagttgatc aattttcttg taaaagtagc gaggattgac aaatcggaga gcgtaccagc
     8521 tacataatct aagaaaatct tttagtttgc tatcaccgtg aactgctcgt gattttttga
     8581 tataagctag ttgacgaaga gccacatact tatagctctt gtcgacaatg ctcaagtctg
     8641 taaatcgatc aattgggaag acatcgatga aaaggctggt atcatgacgc ttgtacttaa
     8701 catggtcttc tataacagta gaagtgtcca aaatcgatgc gaaattatgg aagtaccaag
     8761 aagatgtatc gtaggaaaga accttgtagc gagggtgatt ttcttcttca ataatcttca
     8821 gtaaacgctc ataatcctca cgataaaggg aaatatcaat atcatcatcc caaggaatca
     8881 tacctttgtg gcggatggct ccaagcatgg ttccataact gagaaaataa ggaatatcat
     8941 gtttcttaca agtctcatca atatagtcca gcagggctag ttgaatttct ttaatttctt
     9001 ttttttctaa atattgcatc ctaatcctcc aatttataag cgtgaaattc atgactgtag
     9061 aagcgttttt cttctggtgg tagggtcata taatctccat aaaattgtgt caaaatagta
     9121 tcaaattttt caggtgcagg aaggcttaaa ttctcaaagg gtaaatcgat tgttttatca
     9181 aaggtaccac ttgggaagac ttccttttcc ttaaattttg aagggataaa agccatatac
     9241 tgcccatttt cacgactata tttttgaatt tctttctcga ttttatttgc aaaataacga
     9301 ggagaaactg gtcgaaggag caaccaaaag gctgttcgta tccaatcttt taaaaggcta
     9361 tccttataga caatattttt atgtttactg aaagacagca gtttgaagct ttccagttta
     9421 taacaagtat caatgacctt aggatcatca aagcgatcca tagggaaaat atcgataaag
     9481 ataccagact cataggtttt tgtatttcga gtatcaataa ttttagtcgt actgtcggtt
     9541 atcttgataa agttgttaaa gtagttctta tcagtttcta aggataggag ttcatacttg
     9601 cttttttcct tttgaaaaat gttaataaat cgttggtagt cttctctagg catggataaa
     9661 tcaatatcgt cgtcccaagg gataaagccc tcatgtcgaa ccgccccaat cagagtaccg
     9721 tagttaataa tatagttgat attgtgcttt ttacagagag tatcaatata atccaaaatt
     9781 tctaattcaa tttgtttggc atcttcaacg gttagttgtt tcattttaaa ctcctatgat
     9841 tttttaaatt tattttttaa ggctagaaca tggtttaaaa attcatagaa aatgctatct
     9901 tttgtgaaga caagtagact aatataagag atagctgata gcaagataat caaaccagta
     9961 ttaatcaaaa atggcaaatt aatgaccata tccacaggat acacgaaatt aatcaggaaa
    10021 taaattgcta caaaggaaag tgaaaagaga gagtatcgaa cagtatagct aaagatatgt
    10081 cccaagtgga tgagttgttt tctatggatg aaaatgatat agaaaacaag tagagaagcc
    10141 tctgataaca tagttgtcag taagtagtat tcgggagcca cgatacggtt gaaaaagagg
    10201 agactattca agcccaaatt gagtagccca gcaaagactg tataaactgt gatacgtttt
    10261 tcatagccat tggtaaagag aatttgggaa ccaagaatgg tatctaaggc caggataatc
    10321 gtacgaaaag cgaagagaga ggtcaagatg ccgcctccga tatatttttc actaccgtaa
    10381 agtaggatgg catttggtcc taaaaccatg agtccaaaac tcagtggaat gataaagaag
    10441 ttaaagattc gactacctct attaaccaga gaaacatagg cttctttgtc tcctttcccc
    10501 agatagtaac tgagacgagg cacactcact ccaattgcac ctgttacaac cccagctata
    10561 acggtcacaa ttcgctgagc tatggtatag taactaacgt tgacatcaat ccctgtttta
    10621 acgaggaaga ggcgatctaa aaaagtgaag agcatattgg cattggcaaa gactaacatg
    10681 gctgtcagag ggagaaagag tggtttaaaa tcacttaggt gaatcttaac aagtttgatg
    10741 tctcttttaa tccaaaaata actaatcagg tagttaatca gcgtcgataa actcatcaca
    10801 agtgtataga caacaatatc gtgttcattt ttaacaaata agaaaataga gaccagcatc
    10861 aggatacgga tgaaggcagt tttgtaaaag agaaaactgt aattttccag agcttcattg
    10921 acccattcga ttgaaaaaat ctgggcaatg agttgaatcc ccataacaag gtagaccttt
    10981 ttgatgattg gattatcagt aaagaagaga ggataggcta ggatatagac agcagtggtc
    11041 aaaatcgtac aagcgatgca caaataaaaa agactagaaa aggttctgtt aagatctttt
    11101 ttgttatcct tgacattact gatagccctt aaaccgtagt tatagacacc ataagttgca
    11161 aagggcaaga aaaatgacaa aatagtgtcg actgagttga agtaaccata gtcagttcgg
    11221 tccaagacac gcgcgacata ggttccagtt aggatgggaa aaataatatt caagacacga
    11281 attcccatgt aagatagagc atttaatttt atacttttca ttcaatttac ctcgtttttc
    11341 attatatcat aaagttagct aataagaaat gaagggcagt aagccaagca atcactttga
    11401 agtttcaaat cttaaatttt aagttttctt taaggaaagt atattattct gaaggactct
    11461 aaaatttcgc agtcatttat tagtaattgc tacagaattc ctagtcatta ctagaaatgg
    11521 actagtttct ttgaataata gaactgcata attctcctat tctagaaggg gaggaccagt
    11581 atttctttta tgataggact agattgtggt ataatagaga gaataagttt ttttagtaag
    11641 acaaaggaga aaatagatga tttatgcagg aattcttgcc ggtggaactg gcacacgcat
    11701 ggggatcagt aacttgccaa aacaattttt agagctaggt gatcgaccta ttttgattca
    11761 tacaattgaa aaatttgtct tggagccaag tattgaaaaa attgtagttg gtgttcatgg
    11821 agactgggtt tctcatgcag aagatcttgt agataaatat cttcctcttt ataaggaacg
    11881 tatcatcatt acaaagggtg gtgctgaccg caatacaagt attaagaaaa tcattgaagc
    11941 cattgatgct tatcgtccgc ttactccaga ggatatcgtt gttacccacg attctgttcg
    12001 tccatttatt acacttcgca tgattcagga caatatccaa cttgcccaaa atcatgacgc
    12061 agtggacaca gtggtagaag cagttgatac tatcgttgaa agtaccaatg gtcaatttat
    12121 tacagatatt ccaaatcgtg ctcaccttta tcaaggacaa acacctcaaa cattccgttg
    12181 caaggacttc atggaccttt atggatctct ttctgatgaa gagaaggaaa tcttgacaga
    12241 tgcatgtaaa atctttgtga tcaaaggaaa agatgtggcc ttggccaaag gtgaatactc
    12301 aaatctgaag attacaaccg taacagattt gaagattgca aaaagtatga ttgagaaaga
    12361 ctagtaaaat gattaatcaa atttatcaac taactaagcc taagtttatc aatgtcaaat
    12421 atcaggaaga ggctattgac caagagaatc atatccttat ccgtcccaac tacatggctg
    12481 tctgtcatgc ggatcagcgt tactatcagg gaaaacgtga tcccaagatt ttgaataaaa
    12541 agcttccaat ggcaatgatt cacgagtcat gtggaaccgt catttctgac ccgaccggaa
    12601 cctacgaggt tggtcaaaaa gttgtcatga ttcccaatca gtctcctatg cagagtgatg
    12661 aagaattcta tgaaaactac atgacaggga cccatttctt gtctagtgga tttgatggct
    12721 ttatgagaga gtttgtttct ctccctaaag atcgtgtggt ggcttatgat gctattgaag
    12781 atacggttgc agccattaca gagtttgtca gtgtgggcat gcacgctatg aatcgtctat
    12841 tgactcttgc tcatagcaag cgggagcgga tcgccgttat tggagatgga agtttagctt
    12901 ttgtggttgc caatattatc aactatactt tgccagaatc agagattgtg gttattggtc
    12961 gtcattggga aaagttggaa ctcttctcat ttgccaaaga atgctatatt acggataata
    13021 ttcctgaaga gttggccttt gaccatgctt ttgaatgttg tggtggtgat ggtactggac
    13081 cagctattaa tgacttgatt cgctacattc gtcctcaggg aacgattctc atgatgggag
    13141 ttagcgaata taaagtcaat ctcaatactc gcgatgcctt agaaaagggc ttgattttgg
    13201 ttgggtcatc tcgttctggt cgcattgatt ttaaaaatgc tatccaaatg atggaagtca
    13261 agaaatttgc caatcgtctt aaaaatatcc tttatctaga agaacctgta agagaaatta
    13321 aagatattca tcgtgtcttt gcaaccgatt taaacacagc ctttaaaaca gtgtttaagt
    13381 gggaagtata agtactggag gttaattgtg gagaaaatca ttaaagaaaa aatttcttcc
    13441 ttacttagtc aagaagagga agtcctcagt gttgaacaac tgggtggaat gaccaatcaa
    13501 aactatttgg ccaaaacaac aaataagcaa tacattgtta aattctttgg taaagggaca
    13561 gaaaagctta tcaatcgaca agatgaaaag tacaatcttg aactactaaa ggatttaggc
    13621 ttagatgtaa aaaattatct ttttgatatt gaagctggta tcaaagtaaa tgagtatatc
    13681 gaatctgcga ttacgcttga ttcaacgtca atcaagacca agttcgacaa aattgctcca
    13741 atattacaaa ctattcatac gtctgctaag gaattaagag gagaatttgc tccttttgaa
    13801 gaaatcaaaa aatacgaatc cttgattgaa gaacaaattc cttatgccaa ctatgaatct
    13861 gttagaaatg cagtcttctc cttagagaaa agactggctg acttaggtgt tgacagaaaa
    13921 tcttgtcata tcgatttggt gcctgaaaac tttatcgaat cacctcaagg acgactttat
    13981 ttgattgact gggaatattc atcaatgaat gatccaatgt gggatttggc tgccctcttt
    14041 ttagagtctg aattcacttc ccaagaggaa gaaactttct tatctcacta tgagagtgac
    14101 caaacaccgg tttctcatga aaagattgct atttataaaa ttttacaaga tactatttgg
    14161 agtctatgga ctgtctataa ggaagagcaa ggtgaagatt ttggtgacta tggtgtgaat
    14221 cgttaccaaa gagctgttaa aggtttggct tcttatggag gttcagatga aaagtaaaaa
    14281 cggagttcct tttggccttc tctcaggtat tttctggggc ttgggtctaa cggttagtgc
    14341 ttatatcttt tcgattttta cagatttgtc accctttgtg gtggctgcag ctcatgattt
    14401 tttgagcatc tttatcttac tagcttttct cttggtaaaa gaagggaaag ttcgcctctc
    14461 aattttctta aatattcgca atgtcagtgt tatcatcgga gccttgctag caggccctat
    14521 cggtatgcag gccaatcttt atgcagttaa gtatatcgga agttctttag cttcatctgt
    14581 atcggctatt taccctgcga tttcagttct attggctttc ttctttttga agcacaagat
    14641 ttcgaaaaat actgtatttg ggattgtctt gattattgga gggattattg ctcagaccta
    14701 taaggttgaa caggttaatt ctttctacat tgggattctt tgtgctttgg tttgtgctat
    14761 tgcatgggga agtgagagtg ttcttagctc ttttgccatg gaaagtgaat tgagtgaaat
    14821 cgaagccctc ttaatccgtc aagtaacttc gttcttgtcc tatcttgtga ttgtgctctt
    14881 ctctcatcag tcatttactg cagtagccaa tggacaattg ctaggtctca tgattgtttt
    14941 tgcagccttt gatatgattt cctacttggc ttattatatc gctatcaatc gcttgcaacc
    15001 agccaaggct acaggcttga acgtgagcta tgtagtatgg acggtcttgt ttgcagttgt
    15061 tttcttgggt gcaccgctag atatgctgac cattatgacg tcacttgtcg tcattgctgg
    15121 agtttatatt attattaaag aataaaggag attcgtgtga aagccattat cttagcagcg
    15181 ggattgggaa ctcgcttgcg tcctatgact gaaaataccc ctaaagcctt ggttcaggtt
    15241 aatcaaaaac ctttgattga gtaccaaatt gagtttctca aagaaaaagg aatcaatgac
    15301 atcatcatca ttgttggtta tcttaaagaa caattcgatt acttgaaaga gaaatacggt
    15361 gttcgtctcg ttttcaatga taaatacgct gactacaata acttttactc tctctatctt
    15421 gtaaaagaag aattggccaa cagctatgtt attgatgctg acaattatct ctttaaaaat
    15481 atgttccgca atgatttgac acgttcgact tattttagtg tttatcgtga agattgtacc
    15541 aacgaatggt tcttggttta tggagatgac tacaaggttc aagacattat tgttgatagc
    15601 aaggcaggtc gcatccttag tggtgtatcc ttctgggatg ctccaactgc agaaaagatt
    15661 gtcagcttta tcgacaaggc ttatgtaagt ggtgaatttg ttgatctcta ttgggacaat
    15721 atggttaagg ataatatcaa agagctagat gtctatgttg aagaattaga aggcaatagc
    15781 atttatgaga tcgatagtgt ccaagactat cgtaaattag aagaaattct taaaaacgaa
    15841 aattaaagat tccaacatct gacaaaatag tcggatgttt tttgattttt tacgaacttt
    15901 tacgaataga tagatgagta gaaaaagaaa tggagttatt tatgaaaatc acaaactatg
    15961 aaatctataa gttaaaaaaa tcaggtttga ccaatcaaca gattttgaaa gtgctagaat
    16021 acggtgaaaa tgttgatcag gagcttttgt tgggtgatat tgcagatatc tcaggttgcc
    16081 gtaatccagc cgtttttatg gaacgttatt ttcagataga cgatgcgcat ttgtcgaaag
    16141 agtttcaaaa atttccatct ttctctattt tagatgactg ttatccttgg gatttgagtg
    16201 aaatatatga tgcgcctgta cttttatttt acaagggaaa tcttgacctc ctgaaattcc
    16261 cgaaggtagc ggtcgtgggc agtcgtgctt gtagcaaaca gggagctaag tcagttgaaa
    16321 aagtcattca aggcttggaa aatgaactgg ttattgtcag tggtctggcc aagggcattg
    16381 acacagcagc tcatatggca gctcttcaga atggcggaaa aaccattgca gtgattggaa
    16441 caggactgga tgtgttttat cctaaagcca ataaacgctt gcaagactac atcggcaatg
    16501 accatctggt tctaagtgaa tatggacctg gtgaacaacc tctgaaattt cattttcctg
    16561 cccgtaatcg catcattgct ggactttgtc gtggtgtgat tgtagcagag gctaagatgc
    16621 gttcaggtag tctcattacg tgtgagcgag caatggaaga aggacgcgat gtctttgcta
    16681 ttcctggtag cattttagat ggactatcag acggttgcca tcatttgatt caagaaggag
    16741 caaaattagt caccagtggg caagatgttc ttgcggaatt tgaattttaa aaatgaccta
    16801 agctagaatt ctaagaaaaa atcaatttta agagaaaatg aacccaacat ttccataata
    16861 aaacgcatat tagcaagttt ttaacacttg ataatatgcg ttttttctaa gtggattagt
    16921 agagtagagg atttttctca tataatactc ttcgaaaatc tcttcaaact acgtcagctt
    16981 ccatctgcaa cctcaaaaca gtattttgag ctgacttcgt cagtcttatc tacaacctca
    17041 aagcagtgct ttgagcaacc tgtggctagc ttcctagttt gcgctttgat tttcattgag
    17101 tataagggaa agtatagtga attgaaataa gatgtgaaca actctatcag gaaagtcaaa
    17161 ttgatttata gaaatatttt agcagccaag gtgcactgtt atagattcaa tacactataa
    17221 tttagtgtaa ttgagaaagg agaaatgatt gtgattgatg ttggctaggt tatgttcaat
    17281 gattcctacc gtctcaaatc ttgtcagtaa ggaaaaataa attcttcaaa agtagagatt
    17341 acaaggcttg tttaagaaag aattcaaaga ccttgacaaa taaaaataaa atggttatta
    17401 taaaaaatgg tctgaaatag atgatgatac ttttcgaaaa tctcttcaaa ctacgtcagc
    17461 tcagctttgc cttgctgtgt tttgagcaag ctacggttag cttccgagtt tgattttcat
    17521 ttactagaaa tgaaactgat gagagatatc agtagacatt tgagtcagga tattatggaa
    17581 aatgataaaa agagctcgtg agattggcat atcagactac taaagtattg agtttgttag
    17641 gattttagcg actagttagc tgggaaagga agatatttgt gacaaataat aaactgtatt
    17701 cgttgataga atttagaaat aaaatatatg aagaattaga actttccaga agtgatttag
    17761 cgattttact atgtgccatg cttatcgcct ctatcggatt aaatatggat tcgactcccg
    17821 tgattattgg agccatgtta atctctcctt tgatgacacc tattctggga gtggggctct
    17881 ctctagctat atttgatttt aaattgttaa gaaaatcttt taaaatatta gctattcaaa
    17941 ttcttgccag tctaatagct tcaacacttt atttttatct ttctcccatt tcgtatgcta
    18001 gttcggagat tgttgctaga acctctccga ctatttggga tgttctcatt gcttttgtag
    18061 gagggatagc aggtattatt ggtgctagga aaaaagagac caataatatt gttcctggtg
    18121 ttgctattgc aaccgccttg atgcctcctc tttgtacagt aggttatgct attgcttctg
    18181 ctaatctaaa atttatcata ggctcctctt acctattcct catcaattgt agctttattg
    18241 tcattgcgac ttatataggt gttaggttga tgatggttaa gaaacattat tttaaagata
    18301 atgaagaaga ctctaaaatg cgtaggattt tgcttctagt tgctgttttg ctgatgattc
    18361 cgagtttcat ctctgcaacg actttagtga gagaaacgtt gaaaaaagag tcccttaaga
    18421 aatttatatc agagcagttt caggggtata atattttgaa aaaaacctat tctaaaaaga
    18481 ctcataccct aaagctaacc atttcaggaa attatttgac agaagaagaa ctcgatatga
    18541 tttcaagtaa gagaggtgac tatggtttaa gtgatgtttc tgttcaagtt tcacaattgt
    18601 ctgattcaga acaacttagt aaggaagagc tggtggagta tttcttccag tatatcaagg
    18661 ataaggaagc aaaagaaaag gagaaagcca ataaatttga tacagagtct gaggagcaat
    18721 aatttcttga gaatagctgg tttctctcgt gagtcttcta tgtatatcaa aggaagactg
    18781 aggttttaag tataaaactt ttcttctatt atagtagcta agtcttgaca gggttcaaaa
    18841 aatggtttac actttataaa gtttattact ttgaaaaggt gtgatactgt ggctacggca
    18901 acaaaaaaga aaaaatcaac agttaaaaaa aatctagtca tcgtggagtc gcctgctaag
    18961 gccaagacga ttgaaaaata tctaggcaga aactacaagg ttttagccag tgtcgggcat
    19021 atccgtgatt tgaagaaatc cagtatgtcc gtcgatattg aaaataatta tgaaccgcaa
    19081 tatattaata tccgaggaaa aggccctctt atcaatgact tgaaaaaaga agctaaaaaa
    19141 gctaataaag tttttctcgc gagtgacccg gaccgtgaag gagaagcgat ttcttggcat
    19201 ttggcccata ttctcaactt ggatgaaaat gatgccaacc gtgtggtctt caatgaaatc
    19261 accaaggatg cagtcaaaaa tgcttttaaa gaacctcgta agatcgatat ggacttggtc
    19321 gatgcccaac aagctcgtcg gatcttggat cgcttggtag ggtattcgat ttcgcctatt
    19381 ttgtggaaga aggtcaagaa gggcttgtca gcaggtcgcg ttcagtccat tgcccttaaa
    19441 ctcatcattg accgtgaaaa tgaaatcaat gccttccagc cagaagaata ctggacagtt
    19501 gatgctgtct ttaaaaaggg aaccaaacaa tttcatgctt ccttctatgg agtagatggt
    19561 aaaaagatga aactgaccag caataacgaa gtcaaggaag tcttgtctcg tctgacgagt
    19621 aaagactttt cagtagatca ggtggataag aaagagcgca agcgcaatgc tcctttaccc
    19681 tataccactt catctatgca gatggatgct gccaataaaa tcaatttccg tactcgaaaa
    19741 accatgatgg ttgcccaaca gctctatgaa ggaattaata tcggttctgg tgttcaaggt
    19801 ttgattacct atatgcgtac cgattcgact cgtatcagtc ctgtagcgca aaatgaggcg
    19861 gcaagcttca ttacggatcg ttttggtagc aagtattcta agcacggtag caaggtcaaa
    19921 aacgcatcag gtgctcagga tgcccatgag gctattcgtc cgtcaagtgt ctttaataca
    19981 ccagaaagca tcgctaagta tctggacaag gatcagctta agctatatac ccttatctgg
    20041 aatcgttttg tggctagcca gatgacagcg gccgtttttg ataccatggc tgttaaattg
    20101 tctcaaaaag gggttcaatt tgctgccaat ggtagtcagg ttaagtttga tggttatctt
    20161 gccatttata atgattctga caagaataag atgttaccgg acatggttgt tggagatgtg
    20221 gtcaaacagg tcaatagcaa accagagcaa catttcaccc aaccgcctgc ccgttattct
    20281 gaagcaacac tgattaaaac cttagaggaa aatggggttg gacgtccatc aacctatgcg
    20341 ccaaccattg aaaccattca gaaacgttat tatgttcgcc tggcagccaa acgttttgaa
    20401 ccgacagagt tgggagaaat tgtcaataag ctcatcgttg aatatttccc agatatcgta
    20461 aacgtgacct tcacagctga aatggaaggt aaactggatg atgtcgaagt tggaaaagag
    20521 cagtggcgac gggtcattga tgccttttac aaaccattct ctaaagaagt tgccaaggct
    20581 gaagaagaaa tggaaaaaat ccagattaag gatgaaccag ctggatttga ctgtgaagtg
    20641 tgtggcagtc caatggtcat taaacttggt cgttttggta aattctacgc ttgtagcaat
    20701 ttcccagatt gccgtcatac ccaagcaatc gtgaaagaga ttggtgttga gtgtccaagc
    20761 tgtcatcagg gacaaattat tgagcgaaaa accaagcgta atcgcctctt ctatggttgc
    20821 aatcgctatc cagaatgtga atttacctct tgggacaagc ctgttggtcg tgactgtcca
    20881 aaatgtggca acttcctcat ggagaaaaaa gtccgtggtg gtggcaagca ggttgtttgt
    20941 agcaaaggcg actacgagga agaaaagatt aaataagagg aggggcccga aagtaaattt
    21001 caggctcctt ttggttagaa cttgacaaaa tacatcattt tatgcgaaac tagaagaaga
    21061 ttattttaac taggagaagt tatgcgtctt atctatctga taattggttt tttatcactg
    21121 gccttggcta ttgttggggt tgttttaccc ttgttgccta caacaccttt ccttttgttg
    21181 tctattgctt gtttctccag aagttccaag cgattcgaag actggcttta tcataccaag
    21241 ctctatcaaa catatgtagc tgattttcgc gagactaagt ctattacgcg tgaacgaaag
    21301 aaaaaaatca tcgtatccat ttacattttg atggggattt ctatttattt tgcccctctc
    21361 ttaccagtca aaatcggtct gggtgctttg accatcttta tcacttatta tctcttcaag
    21421 gtcattccag acaaagaata gttaaaacag tagttattta ccttgataaa attgaaagca
    21481 tattcataac aatatgatat aataaatttg aagtaatatt caaggagaat caaatgattt
    21541 acgaattttg tgctgaaaat gtgactttac ttgaaaaagc gatgcaggct ggagctcgtc
    21601 ggattgaact ctgtgataat ctagcagttg gtgggacaac acctagctat ggagtgacta
    21661 aggcagcggt tgaactggca gctaactacg atacaaccat catgaccatg attcggccac
    21721 gtggtggtga ctttgtctat aatgacctag aaattgctat catgctagaa gacatttgtt
    21781 tgactgctca ggctggaagt caaggggttg tatttggagc tttaactgct gataaaaagt
    21841 tggataagcc taatctggaa aagttaattg ctgcatcaaa aggaatggaa attgtctttc
    21901 acatggcctt tgatgaacta agtgatgaag atcaaccgga agctattgac tggctcagtc
    21961 aagccggtgt cactcgtatc ctaactcgtg ctggtgtgtc tggcgactcc ttagaaaaac
    22021 gttttgttca ctatcacaga attttggagt acgctaaagg taaaattgaa attctaccag
    22081 gtggggggat tgaccttgac aaccgtcaaa cctttattga ccaggtgggg gtaacacaat
    22141 tgcatggtac taaggttgtt ttttaaaaaa tagaaaggaa ctgctagcct tgggtagcag
    22201 ttttcactta tgtttgaaat ttttaaatcc tatcaattta atcaagaaaa ggctcatgat
    22261 tatggtttta tagaaaatag cgaagtctgg acatatagtt gccagatttt gcaaggtgac
    22321 tttgtcatga ctgtgtccat cactgctgat aatgtgaact ttcaagtctt tgaccaagag
    22381 actggtgacc tctatcctca cgttcatatg gaaagcatga ggggaagttt tgtcggaaat
    22441 gtccgtgagg cttgtctgga gattctttac cagattcgga aggcttgttt tgatgtgcaa
    22501 gattttatct gtcatcagac taagcgtatc atgactcaag ttcaggaaaa gtatggaaac
    22561 cagttggagt atctgtggga aaaatcgcct gatacagctg tattgcgcca tgaaggcaat
    22621 caaaagtggt atgccgtctt gatgaaaatc tcttggaata agctggaaaa gggcagagaa
    22681 ggacaagtgg aagcagtcaa cctcaagcat gaccaagtag ctaatttgct ttcacaaaag
    22741 gggatttatc cagccttcca tatgagcaag cgctactgga ttagtgtgtc ccttgatgat
    22801 actttatcag atgaagaagt actggaattg atagaaaaaa gttggaactt aacctctaaa
    22861 aaatgaaata ttttaataat tttcatgaac tttcaattag ctaaatattc tttactgaag
    22921 aaatttttag aaaatatagg atttaccaca ctagaggaat atggtgccat cttcaaatac
    22981 ctgattgaga atgtcaagac ggatcgtcag atcatctgtt cgcctcactg tcatgatgac
    23041 ctcggaatgg cagtggcaaa tagccttgct gctgtcaaga atggtgcagg acgtgttgaa
    23101 gggactatca atggtattag ggagcgagct gaaaatgctg ctttggaaga aattgcagtg
    23161 gctctcaata ttcgccaaga ttactaccaa gtagaaacca gtattgtcct aaatgagacc
    23221 atcaatacgt cagaaatggt ttctcgcttc tctggtattc cagttcctaa aaacaaagcc
    23281 gtcgttggtg gcaatacctt ctcccacgaa tctggtattc accaagatgg agtccttaaa
    23341 aatcctctca cttatgagat catcacacct gaattggttg gtgttaagat tccgcttgga
    23401 aaattatctg gtcgccatgc ttttgttgag aaactgagag aattggccct agattttaca
    23461 gaagaggata tcaaaccact ctttgctaag ttcaaggcac tggccgataa gaagtaagaa
    23521 atcacagatg cagatcctcg agctttggta gctggaacca tggttgaaaa tccagaaggc
    23581 ttccactttg atgatttaca acttcaaact catgcagata atgacattga agcgctcgtt
    23641 agcctagcca atatggatgg tgagaaagtc gaatttaatg cgacagggca aggttccgtt
    23701 gaagcaatct ttaacgctat cgataagttc tttaaccaat ctgttcgttt ggtgtcctac
    23761 actatcaatg cggtaacaga tggaatcgat gcccaggatc gggttttggt cactgttgaa
    23821 aacagagata cagaaaccat ctttaatgca gcagggcttg attttgatgt gttgaaggct
    23881 tctgctattg cctatataaa cgctaatacc tttgttcaaa aagagaatgc aggtgagatg
    23941 ggacgcagtg tttcttacca cgatatgcct agtgtgtaaa ggagaaggct atggcaaaga
    24001 aaatagtagc tctagtagga gacggaattg gcccagaaat catgtaggct ggtttagaag
    24061 ttctggaggc tctagctgaa aaaacaggtt ttgactatga gattgacaga cgaccgttcg
    24121 gaggtgcaga tattgatgca gcaggacctc ccttacctga tgaaaccctt aaggcaagta
    24181 gggaagcaga tgctatccta ctagcagcta tcggtagtcc tcagtatgat ggagcagcgg
    24241 ttcgccctga acaaggcctg atggctctcc gtaaggaact caatctttac gctaatattc
    24301 gtcctgtaaa aatctttgac agtctcaagt atttgtcacc actcaaaccg gaacgaattt
    24361 ctggtgtaga ctttgtcgtg gtgcgtgaat tgacaggcga gatttacttt ggagatcata
    24421 ttcttgaaga gcgcaaagcg cgtgatatca acgactatag ctatgaggaa gtggagcgga
    24481 ttattcgcaa agcctttgaa attgcaagaa atcgcagaaa aatcgttact agtatcgata
    24541 agcaaaatgt tctagcgacc tcaaaactct ggcggaaagt agctgaggaa gtcgcacagg
    24601 atttcccaga tgtaaccttg gaacaccagc tggtagactc agctgctatg cttatgatta
    24661 ccaatcctgc taagtttgat gttattgtaa cggagaatct ttttggagat attttatctg
    24721 atgaatcaag cgtcttatct ggtacacttg aggttatgcc atcagccagt cattctgaaa
    24781 atggaccaag tctctatgaa cctattcacg gttcagcacc tgatattgca ggtcaaggaa
    24841 ttgccaatcc tacttccatg attttatcag ttgccatgat gttgagagat agtttcggac
    24901 gttatgagga tgcagagcgt atcaaacatg ctgttgagac aagtctggcg gcaggaattt
    24961 taacgagaga tataggaggt caggcttcaa caaaggaaat gacggaagct attattgcaa
    25021 ggttatgaag ttagacgaaa aaattactct agtccttttg atttggaatg tcatcatttt
    25081 cttgatttat ggcattgaca aattcaaggc aagaagaaga acttggcgca tccaagagaa
    25141 aatcttactc attttagccc ttacttgtgg tggttttggg gcctggttag ctggaatcac
    25201 ttttcaccac aagactcgaa aatggtactt taaaacagtt tggtttcttg ggatggtgac
    25261 cacactagta gccttatatt ttatttggag gtaatggatg gcagggtctt cgagggaaca
    25321 cgctgcttgg gttctagcgg actatggttt taaggtcgtg attgcaggat ctttcggtga
    25381 cattcattac aataatgaac tcaataatgg cctgttgcca atcgttcagc ctagagaggt
    25441 tagagagaaa ctagcccagc taaaaccaac cgaccaggta actgtggact tggaacaaca
    25501 aaaaatcatc tcaccagttg aagaattcac cttcgagata gatagcgagt ggaaacataa
    25561 actcctaaat agtttggatg atatcggtat taccttgcag tatgaagagt tgattgctgc
    25621 ttatgaaaaa caacgaccag cctactggca ggattagaaa aaatagaaaa ggaaatatag
    25681 taaactgaaa taagatgtaa acaaatgaat tagagcttaa catccatttc cagcaatttt
    25741 ttagaaacta cagtggacta ttctggattc aacacattat aaaattatga caaaacacat
    25801 tcacaagaag gctacgacat tttaaaaggt gagggcggat gtatcgtttg ccctactaaa
    25861 gttggttaca ttatcatgac cagcaacaag gcaggacttg agcgtaagtt cgcagccaaa
    25921 gaacgtaagc gtaacaaacc aggtgttgtt ctctgcggta gcatggatga acttcgcgct
    25981 ttagcgcaac tcaacccaga aattgaagca ttctactaaa aacattggat gaagatattc
    26041 ttcttggttg tatccttcct tggaaaccag aagcctttga aaaactcaaa gcatacggga
    26101 atggccgtga agaacttatg actgatgtac gtggtactag ctgttttgtt atcaagtttg
    26161 gaaaagcagg tgaacaattg gctgccaagc tttgggaaga aggtaaaatg gtctacgcct
    26221 catatgcttc aatgacaaaa cgattgaaac tcgctatgag agcaaggtgt aatggtgtct
    26281 atggtcgata aggacggcaa actcatccca gaacaaggag gagcacgttc aacttcacca
    26341 gcaccagttg tgatccgtaa agggcttgac attgataaaa tcatgatgca cctgtcagat
    26401 acttttaact catgggacta ccgtcaggtt gagtattatt aagataaaaa aagaagtcta
    26461 gtgttatgag atattaaagc tcctaacact ggactttttg tttagaattt cttttctttt
    26521 tctataggat atggtattct atgtagaaaa tatatgttaa taagtaatgc caatatttaa
    26581 acatcattag taaaaggagt tagattgatg aataaaagaa aagttagttt agaagatttt
    26641 tataaatggt atagtctaaa taaagaagag ttattaaata aggcaactgt tggtgaaaag
    26701 tttaatgata aattaaaaga agagtttctc caggaatggc ctttggatag gattttaaca
    26761 atgtcaatcg atgaatatgt aataggaaag ggacagcaaa ataagtcttt atgctacgct
    26821 cttgagaagg gaaaatacaa aaatctattt cttggaattt ctggtggctc agcttcaaaa
    26881 tttggtattt attggaataa aaaaacaaac aaatataaag atcaagctaa taatgagatt
    26941 tcagagttgg atcagcgatt ttcaaaatta aaatcagatt tgtatgaaat tatcaaagaa
    27001 ggtattcgtt ttaactttga aaatcctatt tttgatatga aaagatcaac aaatgaattt
    27061 attggtcgtt ctgctatggt gacaaaatta ctttgtatct atactgaggg agatcctttc
    27121 tttggtgtaa atattaatag tcagaaagaa ttttggaacc actttgtttc tcagacaaat
    27181 caaggtggac cttatctgca aaatcataaa ataattgaac tagtgtccaa aacttatcct
    27241 gagttggagc catcgaaatt aggaactatg ctttttgagt attctaagct ttttatggaa
    27301 aataaggaag acaatagtac aatggattca tcaaacaatt ttcgtcatca attaactcaa
    27361 tctctattaa agtctccaaa cctcatcctc cgtggtgctc ctggcacagg aaagacttat
    27421 cttgctaaag aaattgccaa agaattaacg gatggcaacg aagaccaaat cggatttgta
    27481 caatttcacc catcctatga ttatacggat tttgtagaag gtttaagacc agtatcaaat
    27541 ggggatggag ctattgagtt taggctacag gacggtattt ttaaagattt ttgtcagaaa
    27601 gcaaaagaaa cccaattgat tggaggacaa gataattttg atgaggcttg ggattcttac
    27661 ttagaatata taaatgttgc tgaagaaaaa gaatatataa caaaaacatc ttacttatct
    27721 attaatagta gacaaaattt gtcagtaaat tatgatagtg gtgtttcagg atggtcacta
    27781 cctagcaaat atgtttacga gttgtataaa gataaaaatt ataataagca agaatactac
    27841 aaaagtggtg gaaaaactgt cctagaaaca ttgagaaaga gatttggttt gaaagactat
    27901 gtttccccaa cagaaattga tactgataag aaattcgtct tcatcatcga tgaaatcaat
    27961 cgtggggaga tttctaagat ttttggcgaa ctctttttct ctatcgaccc tggctatcgt
    28021 ggtgaaaaag gaagtgtttc tacccaatat gcaaatctac acgaaactga tgaaaagttc
    28081 tatatccccg aaaatgttta catcatcgga actatgaatg atattgatcg ttcagtggat
    28141 acctttgatt ttgctatgcg tcgtcgtttt cgttttgttg aagttactgc cgagggtcaa
    28201 gttggcatgt tggataaaga gctgaatatc catgcagaag aagcaaaaat tcgtctaaga
    28261 aacttgaacg ctgctatcga aaatgttcag gaattaaaca gtcattatca tattggacca
    28321 agttattttc ttaagttgaa ggatgtagat tttgactatg aattactctg gtctgattat
    28381 attaagcctc tcctagaaga ctacttgcga ggttcttatg atgaggttga aactttggaa
    28441 actttgaaaa aagcatttga actgacaaat aatgagcaaa aagatcaggc agtagctgat
    28501 gacaatgaag gtgatgaaaa cgatgatgcg gattactgat aatcaacaca agattattaa
    28561 agaaaaattt gttgaagaat atcctaaact aagcaatctt cttttagaca gaaccttgga
    28621 aagtctatcc caagatgaac gtattttcat ttttccaaat gatttgactc atactcctga
    28681 tttggataag gaccaaaaga tttttgaaac agtcaatcag aaaatcaaga cagggaacgt
    28741 gattggtttt cttggatatg gtcaggaaag attaacgatt tcctcacgat tttctgatga
    28801 gagtaatgac cattttttgc attatctctt aaacaaggtt ctttatatca atctcactag
    28861 tttagatgtt gctttgtctc gtgaagagag gctttatcaa cttttgatgt atctcttccc
    28921 caagtatcta caagctgcta ttcgaaaagg tctttataag gaatatcatc gattttttca
    28981 taacgacagt aatgttaagg gagtgattga tgtaagaagc catctcaaga aaaatcttcc
    29041 tttcacggga aatattgcct acgcaacgag agagttcacc tatgataatc ccctcatgca
    29101 gttggtccgt cacactattg aatacattaa gaatcagaaa agcattggtc aaggggtact
    29161 agataatctc tcaactagtc gtgaaaacgt atctgaaatc gtgcgtgtaa cgccctctta
    29221 taaactagct gatcgtgcta agattactcg gagaaatcaa tctaaaccta tacgtcatgc
    29281 atactttcac gagtacagaa acttacaaga actttgtctg atgatcctaa accaagaaaa
    29341 gcacggttta gggtatcaag atcaaaaaat ctatggtatt ctctttgatg ttgcctggct
    29401 ttgggaagag tatgtttaca ccttgttgcc aaaaggtttt gtacatccca gaaataagga
    29461 taagacggat ggaatttcag tattttctgt tgggaaacga aaagtatatc cagattttta
    29521 tgacagagaa cgaaagattg ttctagatgc aaaatataaa aaactggaat tgactgaaaa
    29581 aggaatcaac cgtgaggact tattccagct gatttcctat tcttatattt taaaagctga
    29641 gaaggctgga ctgatttttc ctagtatgga gcagtcagta aatagtgaaa taggaaaagt
    29701 agctggctat ggagctcaat tgaagaagtg gtctattcga atccctcaga atgcctcatc
    29761 ctatagtgca ttttgtaaaa tgatggaaaa ttcagaagaa aattttaaag cgattattga
    29821 tgaagaagtg gggagaaaat aatttcccct ctttctttta tttttaacac aagtaaaacc
    29881 cgaacgatat attttaattc ataaaaaaaa ttgacaaaaa ctgtactttg gtttataata
    29941 aattaaggaa acgtcggaaa aggcgtagtg atgcgagagc ataggtaggt cattacaaaa
    30001 gaaacgagac atcgatatgt taaatgaatt tccaattttt gattacgaag atattcaatt
    30061 gattccaaat aaatgtgtca ttaaaagccg tgcagaagcg gatacaagtg tcactttagg
    30121 aaatcacacc tttaaactac ctgttgtgcc agcgaatatg cagacgattt tggatgaaaa
    30181 tgtagcagag caactggcta aaggtggtta cttctacatt atgcaccgtt ttgatgaggc
    30241 aggacgcatt ccttttatta aacgaatgca caatcaaggg ctcattgctt ccatatctgt
    30301 cggtgttaag gactatgagt atgatttcgt tagacagctc aagactgatg ctcctgagta
    30361 tatcactatt gatattgctc atggtcatgc ggatagcgtg atttctatga ttcaacacat
    30421 caagaaagaa ttgccagata cctttgtcat tgctggaaat gtgggaacac cagaagctgt
    30481 gcgtgaattg gaaaatgctg gtgcggatgc tactaaggtc ggaatcggtc ctggtaaggt
    30541 ttgtatcacc aaggttaaga ctggttttgg tacaggtggt tggcagttgg ctgctctacg
    30601 ctggtgtgtc aaggctgcgc gtaaaccgat tatcgctgat ggaggaattc gtactcacgg
    30661 tgatattgcc aagtctatcc gcttcggtgc tagcatgatc atgattggtt ccctctttgc
    30721 aggacatatt gaaagtccag ggaaaacgat tgaagtcgat ggtgaacagt tcaaagaata
    30781 ttatggttca gcctcacaat atcaaaaagg tgcttacaaa aatgtggaag gcaaacgtat
    30841 cttgcttcct gctaaaggtc atctgcaaga cactttaact gagatggaac aagaccttca
    30901 aagtgctatt tcttatgcag gtggacgtca ggttgctgac cttaaacacg ttgattatgt
    30961 gatcgtgaaa aactccatct ggaatgggga tgcttcccac taagacgggg tctttgacta
    31021 aaaaacttgt tattagagca aatttctgtt ataataaaac aagtttccac ccttagtgta
    31081 atggatatca cgtaagattc cggttcttga gatgggggtt cgattccctc agggtggatg
    31141 taaacattct aaaaagcctt taatagggct tttttcttta cactgctcta aatttaccgc
    31201 taaaactgag aatctctgtc taaagaattt ccaaatgctt tccagtcccg ttttagagtg
    31261 actcaggggg ctttttttga tataataaaa aggactgtta tcagttagaa agaggttggt
    31321 atgaaagaat tacaaactgt actaaagaac cattttgcaa tcgaatttac agacaaaaag
    31381 ttactggaaa ctgcctttac tcatacgagt tatgccaatg agcaccgcct cttaaaaatt
    31441 tcacataatg aacgcttgga atttttagga gacgctgttc tacagttatt gatttcagaa
    31501 tatctgtata aaaaatatcc taaaaagcct gaaggtgacc tatcaaaact ccgtgctatg
    31561 attgtccgtg aggagagttt agctggtttt gcgcgtgatt gccagtttga ccagtttatc
    31621 aagttgggta aaggggaaga aaaatctggt ggtcgcaatc gtgacaccat tcttggtgat
    31681 gcctttgaag cctttcttgg tgcccttctt ttggataagg atgtggccaa ggtcaaggaa
    31741 tttatctatc aagtcatgat tcctaaggtt gaagcaggcg aatttgagat gattacagac
    31801 tataaaaccc atctccaaga gttacttcag gtcaatggtg atgtggctat tcgttatcag
    31861 gtgatttctg aaacagggcc tgctcacgat aaggtctttg atgtagaagt tcttgttgaa
    31921 ggtaagagta tcggtcaagg ccaaggtcgt tctaagaaat tagcagagca ggaagctgcc
    31981 aaaaatgccg ttgagaaggg gctggattca tgtatttaaa ggaaatcgaa attcaggggt
    32041 tcaagtcttt tgctgataag accaaggtcg tttttgacca aggtgtgacg gcagttgttg
    32101 gaccaaatgg atctggaaag tccaatatta cagaaagtct gcgttgggct ttgggggagt
    32161 ctagtgtcaa gagtctccgt gggggcaaga tgccggatgt catctttgct ggaacagaaa
    32221 gtcgcaaacc gctcaattat gcttctgtag ttgtgactct ggataatcat gacggattta
    32281 tcaaggatgc aggtcaagaa atcagggtgg aacgccatat ctatcgtagt ggagatagcg
    32341 aatacaagat tgacggcaag aaagtccgtc tgcgtgatat tcatgacctc ttcttggata
    32401 ctggattggg acgagattcc ttctctatta tttcccaagg gaaggttgag gagattttta
    32461 attccaagcc tgaggaacga cgagctattt ttgaagaagc tgctggagtt ttaaaataca
    32521 agactcgcag aaaagaaacc gagagtaaac tgcagcaaac tcaggataat ctggaccgct
    32581 tagaggacat tatctacgag ttggataatc aaatcaagcc tcttgagaag caagctgaga
    32641 atgcccgtaa gtttttagac ttggaaggac aacgtaaggc tatttattta gacgttctgg
    32701 ttgctcaaat caaggaaaat aaggctgaac tagagtcgac agaagaagag ttggctcagg
    32761 ttcaagaact cttgatgagt tattaccaaa agcgtgaaaa attagaagaa gaaaatcaaa
    32821 ctcttaaaaa gcaacgccaa gatttacagg ctgaaatggc caaagaccaa ggcagtttga
    32881 tggatttgac cagtctgatt agtgacttag agagaaaatt agccctatcg aaactggaat
    32941 ctgagcaagt agccctcaat caacaggaag cacaagcccg tttggctact ttggaggata
    33001 agagaagttc actcagccaa gaaaaatctg ataaagaaag ctctttagcc ctcttggaag
    33061 aaaatctagt ccaaaataat caaaaactca atcgattaga ggctgaattg ctagcttttt
    33121 cagatgatcc tgatcagatg attgagctct tacgtgaacg ctttgtggcc cttttacaag
    33181 aagaagcaga tgtctcaaac caactgaccc gtattgagaa tgagttggaa aatagtcatc
    33241 agctttctca aaaacaagca gatcaactag aaaagctgaa agaacagttg gctacagcta
    33301 aagagaaggc tggtcagcaa aaggctgagc ttgaaactgc caaggagcag gttcagaaat
    33361 tattggccga ctatcaagtc tgtgctaagg agcaagagga gcagaaaact tcctatcaag
    33421 ctcaacaaag tcaactcttt gaccgtctgg atagtctcaa aaacaagcag gctagagcgc
    33481 aaagtttgga aaatatcctg agaaatcata gtaactttta tgcaggtgtt aagagtgttc
    33541 tccaagagaa agatcgtcta ggtgggatta ttggagcagt tagtgagcac ctgacctttg
    33601 atatgcatta tcaaactgcc ctagaaattg cgcttggagc gagtagtcag cacattattg
    33661 tagaagatga gaatgcggca accaaagcca ttgatttact caaacgaaac agatctggtc
    33721 gtgcaacctt ccttcctttg accactatca aggctcgtac gatttctagt cagaaccaag
    33781 atactattgc tgcaagtcca ggatttctgg gcatggcaga tgagctggtt actttcgata
    33841 ctagactgga agccattttc aagaatttgc tagctacaac ggccattttt gataccgtgg
    33901 agcatgcgcg tgcagcagcg cgccaggttc gttatcaggt tcgtatggtg acattggacg
    33961 gaacagagct gcgcacaggt ggttcttatg caggtggagc taatcgccag aataacagta
    34021 ttttcatcaa gccagaactg gagcaattac aaaaagaaat tgctgaagaa gaagcaagtt
    34081 tgcgttcaga tgaagtgagt ttgaagaact tgcaagatga gctagctaga ttgacagaaa
    34141 gattagaagc catcaaatct cagggagagc aggctcgtat tcaggagcaa ggcttgtccc
    34201 tcgcctatca gcagaccagt cagcaagttg aagagctaga aactctttgg aaactccaag
    34261 aagaggaatt aaatcgtctt tctgagggag aatggcaagc ggataaggaa aaatgccaag
    34321 agcgccttac tacaatcact agtgaaaaga ataatctgga agctgagatt gaagagatta
    34381 agtctaataa aaacgccatc caagaacgtt atcaaaactt gcaggaagag ctagctcaag
    34441 ctcgtctact taagacagaa ctgcaagggc aaaaacgtta tgaagttgct gatattgaac
    34501 gcttaggtaa ggaactagat aatcttgata ttgagcaaga agaaattcag cgccttcttc
    34561 aagaaaaggt tgacaatctt gagaaagttg atacggattt gctcagtcaa caggctgatg
    34621 aagccaaaac tcaaaaaaca aatctccaac aaggtttgat tcgcaagcag tttgagttgg
    34681 atgatattga gggtcaactg gatgatattg ctagtcattt ggatcaggct cgccagcaga
    34741 atgaagagtg gattcgcaag caaactcgtg ctgaagccaa gaaagaaaag gttagcgagc
    34801 gcttgcgcca tctacaaaat caattaacag accagtacca gattagctat actgaagcac
    34861 tagaaaaagc gcatgagttg gaaaatctca atctggcaga gcaagaggtg caggatttag
    34921 agaaggctat tcgctcactg ggacctgtca atttagacgc tattgaacag tacgaagaag
    34981 ttcacaaccg tctggatttc ctaaatagcc aacgtgatga tattttgtct gcgaaaaacc
    35041 tgcttcttga aaccatcaca gagatgaatg atgaggtcaa ggaacgcttt aaatcaacct
    35101 ttgaggccat tcgtgagtcc tttaaagtga ccttcaagca gatgtttggt ggaggtcagg
    35161 cagacttgat attgactgag ggcgaccttt taacagctgg tgtggagatt tctgttcaac
    35221 ctccaggtaa gaaaatccag tcgcttaacc tcatgagtgg tggtgaaaaa gctctatcgg
    35281 ctcttgcctt gcttttctcc attattcgtg tcaagaccat tccttttgtc atcttggatg
    35341 aggtagaggc tgcgctagac gaagccaatg ttaaacgttt cggggattat ctcaaccgct
    35401 ttgataagga cagtcaattt attgtcgtaa cccaccgtaa ggggaccatg gcagcggccg
    35461 attctatcta tggagtgacc atgcaagaat cgggtgtttc aaagattgtt tcagttaagt
    35521 taaaagattt agaaagtatt gaaggatgac aattaaacta gtagcaacgg atatggacgg
    35581 aaccttccta gatgggaatg gacgctttga tatggatcgt ctcaagtctc tcttggcttc
    35641 ctacaaggaa aaagggattt actttgcggt ggcttcgggt cggggatttc tgtctctgga
    35701 aaaattattt gctggtgttc gtgatgacat tattttcatc gcggaaaatg gcagtttggt
    35761 agagtatcaa ggtcaggact tgtatgaagc gactatgtct cgtgactttt atctggcaac
    35821 ttttgaaaag ctgaaaacgt caccttatgt agatatcaat aaactgctct tgacgggtaa
    35881 gaagggttca tatgttctag atacggttga tgagacctat ttgaaagtga gtcagcatta
    35941 taatgaaaat atccaaaaag tagcgagttt ggaagatatc acagatgaca ttttcaaatt
    36001 tacaaccaac ttcacagaag aaacgctgga agctggtgaa gcttgggtca atgataatgt
    36061 ccctggtgtc aaggctatga caactggctt tgaatctatt gatattgttc tggactatgt
    36121 cgataagggt gtagctattg ttgaattagc taaaaaactt ggtatcacaa tggatcaggt
    36181 catggctttt ggagacaatc ttaatgactt acatatgatg caggttgtgg gacatcctgt
    36241 agctcctgaa aatgcacgac ctgaaatttt agaattagca aagactgtga ttggtcacca
    36301 taaggaacgg tcggttatag cttatatgga gggcttataa tggcagatat aaaattgatt
    36361 gcattggact tggacgggac cttgctgact actgataaaa ggctgacgga tcgtaccaag
    36421 gaaaccttga aagctgcgcg tgatcgtggt atcaaggtcg tattgacaac tggtcgtccc
    36481 ttaaaagcca tggatttctt tctccatgag ttagggactg acggtcagga agatgagtat
    36541 accattactt ttaatggtgg attagttcag aaaaatacag gagaaatcct tgataaaaca
    36601 gtcttttcat atgatgatgt ggcacgtttg tatgaagaaa cagagaaatt atcactgcct
    36661 ctcgatgcca tctcagaagg aacagtttat caaatccaat cggaccaaga aagtctttat
    36721 gccaaattca atccagcttt gacctttgtt ccagtggact ttgaagactt atctagtcaa
    36781 atgacctaca acaaatgcgt gactgccttt gctcaagaac ccttggatgc agccattcag
    36841 aagatttctc cagaattgtt tgaccaatat gaaatcttta aatcacgtga aatgttgcta
    36901 gaatggtcac caaagaatgt tcataaagca acaggtttgg caaaactaat cagccatctt
    36961 ggaatcgacc aaagtcaagt gatggcttgt ggtgacgagg ccaatgacct ctctatgatt
    37021 gaatgggcag gtcttggtgt tgctatgcaa aacgctgttc ctgaagtaaa ggcagccgca
    37081 aatgtagtga cgccgatgac caacgatgag gaagctgtcg cctgggctat cgaagaatat
    37141 gtgctaaagg agaactaaga tatgggattg tttgaccgtc tattcggaaa aaaagaagaa
    37201 cctaaaatcg aagaagttgt aaaagaagct ctggaaaatc ttgatttgtc tgaagatgtt
    37261 gatcctacct tcacagaagt tgaggaagtt tctcaggaag aagcagaggt tgaaattgtt
    37321 gaacaagctg tgttccaaga agaggaaatc caagacacag ttgaagaaag tctggattta
    37381 gagccagtta tagaagtttc tcaaaaagaa gtcaaagaat ttccacactc agaagaaggg
    37441 aatactgagt ttctagagac tgtagaagaa aataattctg aaattcttga agcagaaagg
    37501 cctcaaacag aagaaactgt tcaggaaaaa tatgaccgca gtcttaagaa aactcgcaca
    37561 ggtttcggtg cccgcttgaa tgccttcttt gctaacttcc gctctgttga cgaagaattt
    37621 ttcgaggaac tggaagaact gttgattatg agtgatgttg gtgtccaagt cgcttctaac
    37681 ttaacggagg aactacgtta cgaagccaag cttgaaaatg ccaagaaacc tgatgcactt
    37741 cgtcgtgtca tcattgagaa attggttgag ctttatgaaa aggatggtag ctacgatgaa
    37801 agcatccact tccaagataa cttgacagtt atgctctttg ttggtgtgaa tggtgttggg
    37861 aaaacaactt ctatcggaaa actagctcac cgctacaaac gagctggtaa gaaggtcatg
    37921 ctggttgcag cagatacctt ccgtgcgggt gcagtagctc agctagctga atggggccga
    37981 cgagtagatg ttccagtagt aactggacct gaaaaagctg atccagccag cgtggtcttt
    38041 gatggtatgg aacgtgccgt ggctgaaggt atcgatattc tcatgattga tactgctggt
    38101 cgtctgcaaa ataaggataa ccttatggct gagttggaaa agattggtcg tattatcaaa
    38161 cgtgttgtgc cagaagcacc acatgaaacc ttcttggcac ttgatgcatc aacaggtcaa
    38221 aatgccctag tacaggccaa agaattttcg aaaatcacac ctttaacggg aattgttttg
    38281 actaagattg atggaactgc tcgaggaggt gtggttctag ccattcgtga agaactcaat
    38341 attcctgtaa aattgattgg ttttggtgaa aaaatcgatg atattggaga gtttaactca
    38401 gaaaacttca tgaaaggtct cttggaaggt ttaatctaat cagaagcaaa aatcctgcaa
    38461 ggcataaact tgcaggaaat ttttttattc taagcgacca tcttgacgat aggcgatatc
    38521 tggttgccaa gtccatttgg caccgaattt ttcaagtagg tcaaagctgg cttgaggtcc
    38581 catgcttcca gctttatagt catgaagtgg ggcaccattt tcatcccaga gctcttcaat
    38641 acggtcaatc aacttccatg atgcaccaac ttcatcccag tggctaaagt tagttgagtt
    38701 gttatttagg acatcataaa tcaatttctc gtatggttct ggagaagcac cagttgcagt
    38761 cgcatctgta cggtaatcaa gtgagttagg agccaagtta aattcttctc ctacttgctt
    38821 cccatttagg ctaagagaga agccttctgt tggttgaata tagatggtca aaatatttgg
    38881 agcaagtggt tctccaaaga tagaatccat ttgtttaaag acgatgttga catgagttcc
    38941 tttttcagtc agtcgtttac ctgtacggaa aaagaaagga acactacgga atcgatcgct
    39001 gtctacaaag aaggcaccag atgtaaaggt ttcagttgtt gattctggat tcacatttgg
    39061 ctcgctacga taagagatgt atttcatgcc atcaatctta ccagagcggt attgcccacg
    39121 gataaagtgt tctttgagtt cttcatcagt tggatgatag aggtttttaa agaccttaat
    39181 cttttcagca cgaatctcgt cttttgtgaa gcttgctggt ttgtccatgg cgaggagcga
    39241 aagaagttgt agagtgtggt tttggaccat gtcacggagg gcaccggatt ggtcatagta
    39301 gccaccacgt tcttctacac ccaagcgctc cgcaaaggta atttgaacat tgtcgataaa
    39361 atccttgttc caaacgtttt caaaaatcaa gtttgcaaag cgaactgcaa agatgctttg
    39421 gatcatttcc ttaccaagat aatggtcgat acggaaaatt tgttcttcgt caaatgttgc
    39481 taggagttcg tcattcaact tgcttgcagt tgcgtaatct gtaccaaatg gtttttcaac
    39541 gatcaagcgc tcaaaacctt tgccatcgac aatgttttca gatttgaggt gtttggcaat
    39601 ggttccaaag aactgaggtg ccatagacaa gaagaagagc ttattgtgtt cagcttggta
    39661 tttttcatta agctcagctt gtaattgacg caaagcaata taatgttccg aatcattgac
    39721 atcatggctt tgatagtaga agtggctagc aaattcttgg gcttgctcgg tactatctgc
    39781 caaatcaagg atggactcga caactacaga ttcaaaatat tccttactcc aaggtctacg
    39841 ggcagttcca ataacggcaa agtgcttgga aagattgccg gatttatata gtctaaaaag
    39901 ggaagggtag agcttgcgtt tagccaggtc tccactcgca ccgaaaattg taacaataac
    39961 cttagatgac atctagctac ctaatttcta tttttattcc tagtcttgct aggtatgagg
    40021 aaacctcatt tcataaactt aattctaaca taattttccg aaaaatcaaa aattccaata
    40081 cgaagtagaa aaactgcaag gaaatcctta cagtttgagt ttagacgttt aagaccttat
    40141 ctaagaactc tttcagacga gggtgttgtg ggttatcaaa gatttggtca ggtgttccgt
    40201 cttcaaggaa ctcgccatct gcagtaaaga taacgcggtt ggcaacctga cgagcaaatc
    40261 ccatctcatg ggttacgata atcatggtca taccttgctc agccaattcc ttcataacgt
    40321 taagtacgtc tccaaccatc tcagggtcaa gggcagaagt tggttcatcg aagagcatga
    40381 tgtctggatt cattgctagg ccacgagcga tggccacacg ttgtttttga ccacctgata
    40441 ggctatctgg attggcatta gctttatctg ctagtccaac cttttcaagc aactccattc
    40501 ccaattcctc agcttcttcc ttagtcatca acttgtgctc aataggagca aaggtgatgt
    40561 tgtccaatac agacatatga gggaagaggt tgaagtgttg gaataccatg ccgatatttt
    40621 cacggacgtg gtcaacattg gttgtttttt cagttaaatc atagccgttc acagtgatgt
    40681 gaccgctagt gacttcttct aaaagattga ggctacggag gaaagttgac ttaccagaac
    40741 ctgaaggacc gatgatacaa acaacatctc cttcatagaa cttagtcgta attcctttta
    40801 ggacttcatt ttttccatag tgcttgtgta aatcatttac atcaattttt aattttgcca
    40861 ttaacgaatc ctcttttcta agcgtttcgc tagtctagtc aaaagtgtga taattacaag
    40921 atagaagata gcaaggattg catacatctt gaaactttgg tagttacgag caatgataat
    40981 cttaccagtt tggaagagtt caaccaaacc gatagcagat acgatagttg tatctttaag
    41041 agcgataacg aattggttga caaagtttgg caacatcaat ttagttgctt gtggcaagat
    41101 aatcttacgc atggtttttc cataagagat acccaagctt cggctggctt ccatttggcc
    41161 aactggaacg gcctgaatac caccacgaac gatttcagcg atataagcag ccgcattgag
    41221 tgagagggca atggttccag ctacaaagtc gttaattggg ctttgttggc ctgtgataga
    41281 ctcgatgaag tttggaattc cccagaagat gaaggctgca agaatcatca atggaatacc
    41341 acgaataacg tcaacgaaaa tctcagagat gacgcgaaga gatttgtatg ggctaacgct
    41401 aaacataccg aagataattc cgatgacaat ggcaatagca aatgagataa gagctagagc
    41461 aagagtgata ccaagaccgc taaggagttg tttgtagttg ttttgaagca agccccagag
    41521 cgttgtttcg tcaacagtac ttgttgaagc agttgaagat tcgctagcta ggtatttgtc
    41581 aagaatcttt tggaattcac cgtttgcttt aaggtttgca agtccgttgt tgaacatttc
    41641 aatcagttct ggatttgctc cttttttaac ggcaaaggct gtttcaccga ttggagttcc
    41701 agagattgga gttttcaatt tttgaccttg gctgatagaa tatttgagaa caggttcatc
    41761 atccataacg gcatcaatgg caccagtgtt taaactgtca tacattgaag aaccatcagc
    41821 aaaggttttg attttgtaac cgtatttgct ttgattttct gttaggaagg tttgagaagc
    41881 agttccgttt ttaacaccga ctgtctttcc ttttagatct tcataagaag caatattgct
    41941 tgattctttg acaccaagaa tggtattagc agtgtagtat gattctgaga agtcaaaagt
    42001 tgccttacga gcatctgtga cagacatccc agcaatgata ccatcggctt gaccagcttg
    42061 gacagcactg atagcagcat caaaaccagg gttggtgatt tcaatttcaa aaccttggtc
    42121 tttagcgatt gccttaatca attccatatc aataccagtg tattggttgc ttgaattttg
    42181 gaaaacaaaa ggtgcaaaag aagaatcgct ggcaatgata tatttagcct taacaggaat
    42241 agcttttaat cctgcgagag tagttgtagt tggcactgct gaagatgatg aagcagtcca
    42301 tttcttgata attttatcaa gactaccatc ttttttcatt tcagccaagg cttggttaaa
    42361 ttcagtaacc aggtgctcgt atttacttcc ttttttcaca ccgaaagcaa aacttcctac
    42421 agcttcacca tccatttcaa tatggagatc ttgaccttgg ttaatggcat attcgataac
    42481 aggtttgtca tccatcatgg catcgatggc accagcactc aagctgttgt tcattaaatc
    42541 accagtgtca aatgttttaa tagtaaagcc gtatttatct ttgattgttt caaggaaacg
    42601 ttgagcggca gttccgtttt taacaccaac ggttttgcca gttaattggt cgtacttgct
    42661 aattttgtgt gactttgtag tagcaatgac aacttttgta tcatagtaag tatcagacat
    42721 ggtgaagact ttttcacgtt ctttagtctt tgtcatccct gccatgatag cgtcggcttg
    42781 cccagcttga accgcattga ctgctgcgtc aaatccagga taggacatct gaatgttcca
    42841 gcctttaatc tcagcgactt tgttaataat gtcaacatca attcctttat aagtttgatc
    42901 tgaatcttta aactcaaaag gtgcataggc ggtatcagaa acaatcttaa tcgtttctgc
    42961 tttggcaata cctaatgaga aaattgggaa taaaattagc aaaaatgcta gaaatttttt
    43021 cttcattttt agtctccttt tccgaatatt ctctcattat atcagaaaaa gtaaaaaaag
    43081 gcaaattgtt atatttttcg tgtcagaaaa tataacattg atttttcctt ttctttcttg
    43141 aattgctatt aaaaagtgct ataataatag tatatataga agaaaagagg acggggatat
    43201 gaagaacaaa agaatattta aagacttcca agcttcaaaa atgagtttaa acatttacac
    43261 aagccccttg ttagcctttg tttttgtctt cataggagag tttgtggctt ttactttgta
    43321 tggtattggc ttgttagctc tcatcggact tgctagaaat tttggagagg ctggtcaaaa
    43381 tcttgcaagc tacttgcaga ccttgcaaca gagcttgacg gataaaacaa gtgactttcg
    43441 tttaatttta ggattactgg cctttggttt tattcttaac actgtgttca gatggacaag
    43501 aaaagttgag aaaagaccta ttcgaacctt gggattttat agagagaatt tcctcagcaa
    43561 tcttctgaaa ggatttagtc taggcttggc actttttctt ctgaccttgt taggtttagt
    43621 ggtcttaggt caatatcgtt tggaatccat tcacttgaat ccttattctc ttgcctttgt
    43681 cgtctttact atcccatttt ggattttaca ggggacagca gaagaagtgg tggcccgtgc
    43741 ttggctactt cctcaattgg cctcaagaac caatctaaaa ctagctattc ttatatctag
    43801 cctgttcttt accctgcttc atatgggcaa ttctagcctc acccctctat ctctagtaaa
    43861 tctcttttta ttcggagttg ccatggctct ttatcttctc aaaactgata cagtttgggg
    43921 tgttgcaggt attcatggtg cttggaattt tgctcagggt aatctctttg ggattttagt
    43981 tagtggtcaa ccgtcaggaa cgtctctgat gaccttttta ccacaaggca atcaagattg
    44041 gctatcaggt ggttcttttg gcatagaagg ttccattatg acaagtctgg tattactact
    44101 gctgattgtc tatcttgcta ataaattaaa gaaagaaaat gaaaggatgt gacttcggtc
    44161 cgtccttttc ttcgtgaaaa tactataagt atgctaaaat aggaatagca catggagaga
    44221 ggattcttat gatcaatcac attacagata atcaatttaa actagtatca aaatatcaac
    44281 catcaggaga tcaaccccaa gctatcgagc agttggtgga taacattgag gggggagaaa
    44341 aagctcagat tctgatgggg gcgactggaa cagggaagac ctatactatg agtcaggtca
    44401 tttctaaagt caataaacca actctggtta ttgcccacaa taaaactctg gctggtcagc
    44461 tctatgggga gtttaaggaa tttttccctg aaaatgcagt tgagtatttc gtatcctact
    44521 atgattatta ccagccagag gcctatgtcc cttctagcga tacctatatt gagaaggata
    44581 gttctgtcaa tgacgagatt gacaagcttc gccactcagc tacctcagcc cttttggagc
    44641 gtaatgatgt tattgtcgtg gcctcagtct cttgtatcta tggtttgggt tcgcccaagg
    44701 aatacgctga tagtgtcgtt agtctccgtc ctggtctaga gatttctcgt gataaactct
    44761 tgaatgactt ggtcgatatt cagtttgaac gtaatgatat tgatttccaa cgcggaagat
    44821 ttcgtgttcg tggggatgtg gtagagattt tcccagcttc ccgagatgaa catgcctttc
    44881 gagtagaatt ttttggagac gaaattgacc gtattcgtga agttgaggct ctgacaggtc
    44941 aggtgttggg agaagtggat catttagcga ttttcccagc gacacacttt gtgaccaatg
    45001 acgaccacat ggaagttgcc attgcaaaga ttcaggccga gttggaggag cagttagctg
    45061 tctttgaaaa ggaaggtaaa ctgcttgaag cccagcgttt gaaacagcgg acagagtatg
    45121 atatcgaaat gttgcgtgag atgggctata ccaatggggt tgaaaattat tctcgccaca
    45181 tggatggacg gagcgaagga gagcctcctt atacgcttct cgacttcttc ccagatgatt
    45241 tcttgattat gattgacgag agtcatatga ccatagggca aatcaagggc atgtacaatg
    45301 gagaccgttc gcgtaaagaa atgctggtta attatggttt ccgtttgccg tctgctttgg
    45361 acaatcgtcc tctccgtcgg gaggagtttg agagtcacgt tcatcagatt gtttacgttt
    45421 cagcgacacc tggtgactat gaaaatgaac agaccgagac agtgattgag caaatcattc
    45481 gtccaacggg actcttggat ccagaggtgg aagtccgtcc gactatggga cagattgatg
    45541 acctcttggg tgaaatcaat gcccgcgttg aaaaaaatga gcgtaccttt atcacaactt
    45601 tgaccaagaa aatggcagag gacttgaccg actacttcaa ggaaatgggt atcaaggtca
    45661 agtacatgca ctcggatatc aagaccttgg aacggacgga gattatccgt gacctgcgct
    45721 tgggtgtctt tgatgtcttg gtcggaatta acctgctccg tgaaggaatt gacgttcctg
    45781 aagtgagcct cgtagctatt ctcgatgctg acaaggaagg tttccttcgc aacgaacgtg
    45841 gactcatcca gactattgga cgtgctgctc gtaacagtga aggccatgtc atcatgtatg
    45901 cagacacggt tacccagtct atgcaacgtg ctatcgatga aactgcccgc cgtcggaaaa
    45961 ttcagatggc ctataatgaa gagcatggta tcgtaccaca gacaatcaag aaagaaatcc
    46021 gtgacctgat tgccgtgacc aaggcagttg ctaaggaaga ggacaaggaa gtcgacatca
    46081 atagcctcaa caaacaagag cgtaaagaac tcgtcaagaa actagaaaaa caaatgcaag
    46141 aagccgtcga agtgcttgac tttgaactgg cggctcagat ccgtgatatg atgttggaag
    46201 tcaaggcctt ggattagggg aatagtatga tttatttaag aaagttaaag agagaagatt
    46261 tgatgtcttt atgggaaatg gcttattcac aacttaatcc agtttggaaa cagtatgatg
    46321 ctccctatta tgatgattat cagtattttt caaattttaa agaattcgaa ctacaaaaat
    46381 cagaatccat tttaagcaac tcaaatcgcc ttggtatttt tgttgatgat aaactagttg
    46441 ggactgtttc gcgttattgg gtatgtaaac aaacaagatg gatggaattg ggaattggta
    46501 tttatgataa aaaattctgg aacactggta ttgggaaagt tgctatgttg cagtggatag
    46561 ataggacgtt tcaggattac ttggagttgg agcatctggg tttgacaact tggtcaggga
    46621 atcttggtat gatgaaactt gctgaaaaat taagaatgaa aaaagaagct catattccaa
    46681 aagttcgtta ttatcaaggt aaatattttg atagtattaa atatggtatt ttgagagaag
    46741 actgggagaa aataaatgac ggttattatc aaatcaatgg aaactcctaa agagatagaa
    46801 ggtaaatccc ttgttcactg gcaaatgtgg agagaggctt atgatgacct tttgcctgca
    46861 gaatttcagg agacaatgac attagaaaga tgtcgactct ttagtcaaaa gtatccagaa
    46921 aatacattga ttgcgatagg tgatctgaag gtagttggtt ttatcagtta tggtaacttt
    46981 cgtgatgaga ctatgcaagc tggtgaaatt attgctttat atgttttaaa agactattat
    47041 ggaaaaggta tcgcacaaaa gttaatgaaa gcagctttga ctgctcttaa tcatttttct
    47101 gaaattttct tatgggtatt gaaagataac aagcgcgcca ttgctttcta tcaaaaaatg
    47161 ggttttactt ttgatggaca agaaaaaata cttgaacttg gaaagcctat aaaggaaaaa
    47221 cgaatggtgt tctattctaa ataattttaa aaaagtaaaa gataatatct ctggtagtaa
    47281 gtctgaaaat ttaataaatt agaaagcgag taaatttatg tcccgttccc aattaacaat
    47341 tttaacaaat atctgtctga ttgaagacct cgaaactcag cgcgtggtga tgcagtatcg
    47401 cgcccctgaa aacaatcgct ggtctggtta tgcctttcct ggaggtcatg tagaaaatga
    47461 tgaggctttt gcggagtctg tcattcgtga aatctacgaa gaaacagggt tgactatcca
    47521 aaatcctcaa cttgtcggca ttaaaaattg gccactagat acaggtgggc gctatattgt
    47581 catttgttat aaggcgactg agttctctgg tagccttcgg tcttcagatg aaggagaagt
    47641 ttcttgggtg caaaaagacc agattccaaa cttggatctg gcctatgata tgctaccatt
    47701 gatggaaatg atggaagctc ccgacaagtc agagtttttc taccctcgcc gtacagaaga
    47761 cgattgggaa aagaaaatct tctagtcttt tactaaataa cctagctgat ccaaggcctc
    47821 ctcgatatag tggaggtctt gttgtgtttc ggcttcgact aggtggtaat ggatgccatc
    47881 tgtcaattca gatagaggtc taaagtcaga atgctcgact tgttctagaa aatgttgcac
    47941 atctctgcga caagacagtt taagcaaggt ttcaatttct ccataaacgg gatggtcaat
    48001 caaggtattc tggacatgcc caccattatc gacaatagca aggagttcct gaccgatttc
    48061 ttcaacttca tgtttcactt tgaaaagttt gtgaacataa ggattggtat caatttgctt
    48121 atagatgtag ccacgattgg tggataggat aggagcgcca tcggctctca aaattgcaat
    48181 atcctgcaca atgacctgac gtgtgacatg aaaatgttcc gccaaacttt ggccattaag
    48241 ggctttagga gcttctttca agagttggag cagggcttgt ttgcgatctt ttgtcatagc
    48301 ttttcctttt aacggcgttt tcgaagcact ttatagacag ctagtgctaa tgtatagtct
    48361 accatactat ggataattgt gccaaatcca actagtacaa atagaacata gaacatattt
    48421 tctacattgg tacccgaagt tgcgtaaaaa aggacacagg ctaatacttc agcaagggca
    48481 tgaacaacag ccaaaacaaa attgaaaacc caggaagatt ttggtttatc tagggtatcg
    48541 gggaattttt gtaggtaaag agctcctaaa gcaccaaaag atatatggga aaaagcccga
    48601 aaaacgataa ccatgggata gccagccatc aaaaatccaa aactagaggc taggatgaca
    48661 aaaactgcca tcaagggcga caagaacatg gctataaaaa tagcgatgtg gctccccaaa
    48721 gtataggaag caggtggaat gacaatcttg aaaggcataa caattggaat caaaatcgca
    48781 atagccgtta aaagggctgt cattgtcata aattgtgtct ttttccgtgt attcacaaga
    48841 atctcctttt taactgcata tacactagta tggtacaata aaccagacaa taaagcaaga
    48901 atttacttgg gtttatagat cattttttag ttaaaagtta tagtagatgg aaactagaat
    48961 agtccacctc tacttctaaa acattgttag cgatttgact gtcctgatcg atttgtcctg
    49021 ttcttatttc gttttactat agtaaagatt tcattaaaaa gaaactgtat agagcaaaat
    49081 ctccaccttc aggtttgaaa gcggagattg tttttatttt ttcaaggttt gtagtcgtgg
    49141 aacaatggct agggttagaa ttgcagaaat gaccaattca gcaattgaat ttgttgagat
    49201 aacggttgcc agaagaagtt ggatatttcc attataaaca tttccaaata ggaagaagat
    49261 tcctccaagg acaaagatag tatttgtcaa ggaaccaagg gctccagcta aaatcagacc
    49321 agtcttgttt ttcatcagtt tatagactaa gtaaggagtt aaaccaatca aaatacgtgg
    49381 gacgatggca atgatagctg agtagatgtt tccgtttggt acgaagggag agaagaggta
    49441 gcttgtcggt agaatcgtaa tcgtgttaac cgtcaagcta agtaatccca tcaaaaatcc
    49501 aagtgtaacc ccaactcgtg gaccataaat aatgctggca ataatgacag gaatatgaac
    49561 aatggtcggt ttgattggaa atggaaaaag gttaaagata agtgagctca gaaagtgtat
    49621 cacgagcatg gtagcaaaaa agatagcaat gggtgcaata ttagagcgtt ttttcatcga
    49681 tagtttcctt tattctttct aaaataattg tgaggtcagc taaagctcct cgtccgtggt
    49741 ctccacaagc tagtagggat tccttaggag caatcagctg atagccgtag gtttctaatg
    49801 ttttcagatt attctgagtt actggatggt catacatttt tgtattcata gcaggagcta
    49861 ttagtttggg aatatgactt ggtagggcta gagctgtact ggttaccatg ttgtccgcaa
    49921 atccgtgagc tagttttgca atagtgttag cagttgcagg taccacgata aataaatctg
    49981 ctttttttcc aagttcgata tgattgacct gatcaggata gggttccttc atgacatcca
    50041 agtggacagg attctgtgag agtacctgta gtgtcaaagg ttggataaac tctgtagcag
    50101 cctgagtcat taagacagtg acttgatggc cttgtttttt tagagaactg actaaatctg
    50161 ccgacttata agaggcgatt gaacccgtta cagccaagag aatgtttgcc atagttttcc
    50221 tttctaagaa tgataggctt gaattttttc aaggaggagt tctgcaattt cttctttagt
    50281 ctggactgtt tgaagctgat ttttctcaac aaatatagct cggtgctgat ctgctgaaat
    50341 ttgagtcagg tcattcgcga tgattaaatc tgcttgattc ttgataagac tttttcgtgc
    50401 aatgtcaacc agatgatctt cggtaacatc aaccagcagt ttgaaaccaa tcagatgaat
    50461 agtgggattc cattccttga ctagggatat gattttgggt gtctttttaa ggaacaaaac
    50521 ctgaacctca tcagttgaag aaatcttggc ctgatgattc tgcttgctta aaaattcttt
    50581 tagattggag ctagcctgaa cttcctcaag ccctgtcata taaacaggag tgtagtcaga
    50641 aacagccatt gagtggatca agacctgata atcctgaaca cgttcttgca tttctattag
    50701 aaggtccttg gtattggtaa tttctcgaat acttaggtta ggatgaggct ctggcttcag
    50761 agctcgtttt gtcgtaatta aacaaacttc atgccctgca gaaagcaaag tctctgtgat
    50821 aattttcccc aagtgacctg tagaatggtt agtgatagag cggacgctat cgatagcttc
    50881 actggtaccg cccgatgtaa ctaaaatttt catagcacta ttgtacacaa aaataagcgg
    50941 taagtaaaat gaaagtgata aatttttggt aaaaacgaag atttactata gtttcaaact
    51001 ataaagccat ataaaattta agaaaggact ctaaaagcct taaaaacaga gatatttacg
    51061 aacgtttaga gagttttagg atgttaaaaa tcttgttttg tgatataatg aattatcata
    51121 taagaggtta gaggaatttt gaatgaaaac agatattgaa atcgcacaga gtattgagtt
    51181 gaagccaatt gttgatgttg tagagaaact tggtatttct tatgacgatt tggagttgta
    51241 cggaaagtac aaggctaaac tcagctttga taaaattcgt gcagttgaga gcaatccagt
    51301 cggtaaattg atcttggtta ctgccatcaa cccaacacct gcaggtgaag gaaagtcgac
    51361 gcttaccatt ggtcttgcgg atgccttgaa caagattggc aagaaaacca tgattgctat
    51421 ccgcgaaccg tctcttggtc cagtcatggg gatcaagggt ggtgctgctg gtggtgggta
    51481 tgcacaagtt ctgccaatgg aagacatcaa cctccacttt actggagata tgcatgctat
    51541 tacaactgcc aacaatgccc tttctgcctt gattgacaac cacttgcacc aagggaatga
    51601 gctggaaatt gatcaacgtc gtatcctctg gaaacgcgtt gtggacttga acgaccgtgc
    51661 gctccgccat gtgactgttg gtcttggtgg tcctctaaac ggtattccac gtgaggatgg
    51721 ttttgatatt acagttgctt cagaaatcat ggcaattctt tgcttggcaa cggacatcga
    51781 ggacttgaaa cgtcgtttgg cgaatatcgt tattggttat cgctatgacc gtacgcctgt
    51841 ttctgtaggt gatttgcagg ttgagggtgc cttggctttg attttgaagg atgctattaa
    51901 gccaaacttg gttcagacaa tttacggtac acctgccttt gtacacggtg gtccatttgc
    51961 caatatcgct catggctgta actctgtttt ggcgacgaca acagcccttc acttggctga
    52021 ttacactgtt actgaagctg gttttggtgc ggaccttggt gctgagaaat tccttgatat
    52081 caagacacca aacttgccaa catctccaga tgcagttgtc attgtcgcaa cccttcgtgc
    52141 ccttaagatg aatggtggtg tggctaaaga cgctctgact gaagaaaatg tagaggcagt
    52201 tcgtgcaggt tttgctaact tgaaacgcca cgttgaaaat atccgtaagt tcggtattcc
    52261 agcagttgta gctattaacg aatttgtatc tgatacagaa gctgaaattg cagtcttaaa
    52321 agaactctgt gcctcaatct atgtaccagt tgaattggct agtgtctggg ctgatggagc
    52381 agaaggtgga gtagcacttg ccgaaacagt tgttaagaca attgctgaaa atccagctaa
    52441 ctataaacgt ttgtacgata atgccctttc tgtccaagaa aagattgaaa aaattgtcac
    52501 tgaaatctat cgtggtagca aagtgaactt tgagaagaaa gctcaaacac aaattgctca
    52561 aatcgttcaa aacggttggg acaaattgcc aatctgtatg gctaaaactc aatacagttt
    52621 ctcagacaat ccaaatgcgc ttggagcacc agaaaacttt gaaattacca ttcgtgaatt
    52681 ggtaccaaaa ttaggtgcag gcttcatcgt tgccttaact ggtgatgtta tgaccatgcc
    52741 aggtcttcca aaacgtccag cagctctcaa catggatgtt gaaagcgatg gaactgtact
    52801 aggcttgttc tagtggattg aaattgactt taagtgagtt tggaaataat atccaagctc
    52861 attttttctc agactgcaag cagttcatca ataagattta tactcttcga aaatctcttc
    52921 aaac
//
LOCUS       DBEJJV010000010        51834 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.010, whole genome shotgun sequence.
ACCESSION   DBEJJV010000010 DBEJJV010000000
VERSION     DBEJJV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 51834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51834
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.010"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            179..1942
                     /gene="aspS"
                     /locus_tag="ACL3GT_000677"
     CDS             179..1942
                     /gene="aspS"
                     /locus_tag="ACL3GT_000677"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HGR0516376.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1920..2861
                     /locus_tag="ACL3GT_000678"
     CDS             1920..2861
                     /locus_tag="ACL3GT_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0516377.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(2903..3100)
                     /locus_tag="ACL3GT_000679"
     CDS             complement(2903..3100)
                     /locus_tag="ACL3GT_000679"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516378.1"
                     /translation="MKIKVQTRKLAAGCSKHCFEVVDRTDEVSSKHGFEVADRTDEVS
                     SKHGFEVADRTDEVSNIYTAR"
     gene            complement(3242..4228)
                     /locus_tag="ACL3GT_000680"
     CDS             complement(3242..4228)
                     /locus_tag="ACL3GT_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0516379.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4238..5038)
                     /locus_tag="ACL3GT_000681"
     CDS             complement(4238..5038)
                     /locus_tag="ACL3GT_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HGR0516380.1"
                     /translation="MLPYPFSFFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5291..6133)
                     /locus_tag="ACL3GT_000682"
     CDS             complement(5291..6133)
                     /locus_tag="ACL3GT_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HGR0516381.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6135..7427)
                     /locus_tag="ACL3GT_000683"
     CDS             complement(6135..7427)
                     /locus_tag="ACL3GT_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HGR0516382.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7538..8809)
                     /locus_tag="ACL3GT_000684"
     CDS             complement(7538..8809)
                     /locus_tag="ACL3GT_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HGR0516383.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9344..10876
                     /gene="malQ"
                     /locus_tag="ACL3GT_000685"
                     /pseudo
     CDS             9344..10876
                     /gene="malQ"
                     /locus_tag="ACL3GT_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004134 - 4-alpha-glucanotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005980 - glycogen catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
     gene            10902..13160
                     /locus_tag="ACL3GT_000686"
     CDS             10902..13160
                     /locus_tag="ACL3GT_000686"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HGR0516384.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14204..14776)
                     /locus_tag="ACL3GT_000687"
     CDS             complement(14204..14776)
                     /locus_tag="ACL3GT_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516385.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            14853..15059
                     /locus_tag="ACL3GT_000688"
     CDS             14853..15059
                     /locus_tag="ACL3GT_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516386.1"
                     /translation="MLKKYFSKYKWTDLFWILFVILTCLYIGNHDLFTLNHQEFSFRG
                     SVWGLVLALYHLLFIDKFVISNRK"
     gene            complement(15398..16246)
                     /locus_tag="ACL3GT_000689"
     CDS             complement(15398..16246)
                     /locus_tag="ACL3GT_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative RNA methyltransferase"
                     /protein_id="HGR0516387.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            16398..16676
                     /locus_tag="ACL3GT_000690"
     CDS             16398..16676
                     /locus_tag="ACL3GT_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6110 family protein"
                     /protein_id="HGR0516388.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            16678..18741
                     /locus_tag="ACL3GT_000691"
     CDS             16678..18741
                     /locus_tag="ACL3GT_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HGR0516389.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLVRTKELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(18819..20075)
                     /gene="tyrS"
                     /locus_tag="ACL3GT_000692"
     CDS             complement(18819..20075)
                     /gene="tyrS"
                     /locus_tag="ACL3GT_000692"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HGR0516390.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            20217..22682
                     /gene="pbp1b"
                     /locus_tag="ACL3GT_000693"
     CDS             20217..22682
                     /gene="pbp1b"
                     /locus_tag="ACL3GT_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP1B"
                     /protein_id="HGR0516391.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            22747..23658
                     /locus_tag="ACL3GT_000694"
     CDS             22747..23658
                     /locus_tag="ACL3GT_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0516392.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            23888..24586
                     /gene="dapD"
                     /locus_tag="ACL3GT_000695"
     CDS             23888..24586
                     /gene="dapD"
                     /locus_tag="ACL3GT_000695"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HGR0516393.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            24654..25784
                     /locus_tag="ACL3GT_000696"
     CDS             24654..25784
                     /locus_tag="ACL3GT_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HGR0516394.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDDAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            25796..26335
                     /locus_tag="ACL3GT_000697"
     CDS             25796..26335
                     /locus_tag="ACL3GT_000697"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HGR0516395.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            26319..26996
                     /locus_tag="ACL3GT_000698"
     CDS             26319..26996
                     /locus_tag="ACL3GT_000698"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HGR0516396.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(27068..27967)
                     /gene="galU"
                     /locus_tag="ACL3GT_000699"
     CDS             complement(27068..27967)
                     /gene="galU"
                     /locus_tag="ACL3GT_000699"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HGR0516397.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(27989..29005)
                     /locus_tag="ACL3GT_000700"
     CDS             complement(27989..29005)
                     /locus_tag="ACL3GT_000700"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0516398.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            29217..29657
                     /locus_tag="ACL3GT_000701"
     CDS             29217..29657
                     /locus_tag="ACL3GT_000701"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0516399.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDK
                     IFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW"
     gene            complement(29780..30202)
                     /locus_tag="ACL3GT_000702"
                     /pseudo
     CDS             complement(29780..30202)
                     /locus_tag="ACL3GT_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(30264..30914)
                     /gene="phoU"
                     /locus_tag="ACL3GT_000703"
     CDS             complement(30264..30914)
                     /gene="phoU"
                     /locus_tag="ACL3GT_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HGR0516400.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(30929..31681)
                     /gene="pstB"
                     /locus_tag="ACL3GT_000704"
     CDS             complement(30929..31681)
                     /gene="pstB"
                     /locus_tag="ACL3GT_000704"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HGR0516401.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(31683..32498)
                     /gene="pstA"
                     /locus_tag="ACL3GT_000705"
     CDS             complement(31683..32498)
                     /gene="pstA"
                     /locus_tag="ACL3GT_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HGR0516402.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(32491..33354)
                     /gene="pstC"
                     /locus_tag="ACL3GT_000706"
     CDS             complement(32491..33354)
                     /gene="pstC"
                     /locus_tag="ACL3GT_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HGR0516403.1"
                     /translation="MIKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(33472..34347)
                     /locus_tag="ACL3GT_000707"
     CDS             complement(33472..34347)
                     /locus_tag="ACL3GT_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HGR0516404.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(34514..35845)
                     /gene="pnpS"
                     /locus_tag="ACL3GT_000708"
     CDS             complement(34514..35845)
                     /gene="pnpS"
                     /locus_tag="ACL3GT_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system histidine kinase PnpS"
                     /protein_id="HGR0516405.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(35846..36553)
                     /locus_tag="ACL3GT_000709"
     CDS             complement(35846..36553)
                     /locus_tag="ACL3GT_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0516406.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(36637..37113)
                     /locus_tag="ACL3GT_000710"
     CDS             complement(36637..37113)
                     /locus_tag="ACL3GT_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HGR0516407.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            37120..37647
                     /locus_tag="ACL3GT_000711"
                     /pseudo
     CDS             37120..37647
                     /locus_tag="ACL3GT_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(37962..39653)
                     /gene="argS"
                     /locus_tag="ACL3GT_000712"
     CDS             complement(37962..39653)
                     /gene="argS"
                     /locus_tag="ACL3GT_000712"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HGR0516408.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            39789..40235
                     /gene="argR"
                     /locus_tag="ACL3GT_000713"
     CDS             39789..40235
                     /gene="argR"
                     /locus_tag="ACL3GT_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0516409.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            40286..42820
                     /gene="mutS"
                     /locus_tag="ACL3GT_000714"
     CDS             40286..42820
                     /gene="mutS"
                     /locus_tag="ACL3GT_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HGR0516410.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            42967..44661
                     /gene="patA"
                     /locus_tag="ACL3GT_000715"
     CDS             42967..44661
                     /gene="patA"
                     /locus_tag="ACL3GT_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HGR0516411.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLAG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(44811..45254)
                     /locus_tag="ACL3GT_000716"
                     /pseudo
     CDS             complement(44811..45254)
                     /locus_tag="ACL3GT_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844241.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            45452..47218
                     /gene="patB"
                     /locus_tag="ACL3GT_000717"
     CDS             45452..47218
                     /gene="patB"
                     /locus_tag="ACL3GT_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HGR0516412.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     NQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            47357..48046
                     /locus_tag="ACL3GT_000718"
     CDS             47357..48046
                     /locus_tag="ACL3GT_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0516413.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            48050..48229
                     /locus_tag="ACL3GT_000719"
     CDS             48050..48229
                     /locus_tag="ACL3GT_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516414.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            48216..49565
                     /locus_tag="ACL3GT_000720"
     CDS             48216..49565
                     /locus_tag="ACL3GT_000720"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HGR0516415.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            49689..51149
                     /gene="gltX"
                     /locus_tag="ACL3GT_000721"
     CDS             49689..51149
                     /gene="gltX"
                     /locus_tag="ACL3GT_000721"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HGR0516416.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            51163..51594
                     /locus_tag="ACL3GT_000722"
     CDS             51163..51594
                     /locus_tag="ACL3GT_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0516417.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNE"
     gene            51718..51789
                     /locus_tag="ACL3GT_000723"
     tRNA            51718..51789
                     /locus_tag="ACL3GT_000723"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:51751..51753,aa:Glu,seq:ttc)
BASE COUNT        15222 a         9887 c        11303 g        15422 t
ORIGIN      
        1 aaccatacct acggtaaggc gacgctgacg tggtttgaag agattttcga agagtattag
       61 cgctaatttt tagggctttc acctgacttt taaagactgg caaacttttc tgatgatttt
      121 catgaagagc ctgcgctttt atggtaaaat agtaacagaa taaaagagga gagaaataat
      181 gaaacgtagt atgtatgctg gtcgtgttcg tgaggaacac atcggacaag aaataacctt
      241 gaaaggatgg gttggccgtc gtcgtgacct tggtggtttg atctttatcg atcttcgtga
      301 ccgtgaagga atcatgcagt tggttatcaa ccctgaaaaa gtatctgcag aggttatggc
      361 aacagctgaa agccttcgta gcgaatttgt tattgaggtg actggtcagg tcgctgcgcg
      421 tgagcaagcc aatgataagt tgccaactgg tgcggttgag ttaaacgtga cagctcttat
      481 tgtgcttaac acagctaaga caacaccatt tgagattaag gatggcattg aggcaaatga
      541 cgatacacgt ttgcgttacc gttaccttga ccttcgtcgt ccagaaatgt tggaaaatct
      601 taaacttcgt gccaaggtga cccactctat ccgcaactac ttggatgagt tggagtttat
      661 cgacgtggag acaccattcc tttctaagtc aacgcctgaa ggggcgcgtg attatttagt
      721 gccgtctcgt gttaataagg ggcattttta cgctcttcct caaagtccac aaatcacgaa
      781 acagctcttg atgaatgctg gttttgaccg ttactaccaa atcgttaaat gtttccgtga
      841 cgaggacttg cgtggagacc gccagcctga atttactcag gtcgacttgg aaacgtcctt
      901 ccttactgag caagaaatcc aagatattac agaaggcttg atcgcgcgcg tgatgaagga
      961 aacaaaaggc atcgaagtaa cgctaccgtt ccctcgtatg aaatacgatg atgctatggc
     1021 tctttacggt tctgacaagc cagatactcg ttttgacatg ttgcttcagg acttgacaga
     1081 agtggtcaaa ggtgtagact ttaaagtctt ttcagaagca cctgctgtaa aagcgattgt
     1141 ggtcaaagga gctgcggaca actattcacg taaagacatc gacaagatga cggaagtagc
     1201 caaacagtat ggtgccaaag gtcttgcttg ggtcaaggtg gttgatggag aattaaacgg
     1261 accagttgcc aagttcttga ctggtatcca agaagaattg acaacagcgc ttgctcttga
     1321 agataaggac ttggttctct ttgtggcgga tacgcttgaa gtggctaatg caacactggg
     1381 tgcccttcgt ggacgtattg ctaaagagct tggcttgatt gataatgata agttcaactt
     1441 cctttgggtg gttgactggc cgatgtttga atggtctgaa gaagaaggcc gctacatgag
     1501 cgcccaccat ccattcacac ttccacagga agagactgct cacgaattag aaggtgattt
     1561 ggctaaggtt cgtgccattg cttacgatat cgtcttgaac ggttatgagc ttggtggtgg
     1621 tagccttcgt atcaaccaaa aagaccttca agaacgcatg ttcaaggctc ttggtttctc
     1681 aactgaagaa gccaatgacc agtttggttt ccttcttgaa gccatggact atggtttccc
     1741 accacacggt ggtttggcta tcgggcttga ccgttttgtc atgttgcttg ctggagaaga
     1801 aaatatccgt gaagtcattg cctttcctaa gaacaacaag gcaactgacc caatgacaca
     1861 agctccatca acagtcgctc tcaaacaact agaggaactc agcttacaag tagaagaaga
     1921 tgaaacaaac aaaacgaatt aagcggtggc gctattatct gcgccgcttt gcttatcaga
     1981 taaaaatttt acgtgtctta caaagtatct ctcgagaaaa gtatgatgag aagatttcgg
     2041 cctctctggt ctatggtttt ttatcagcag tagcagttaa tttctttttt caaccagggc
     2101 atgtgtattc gagtggtgca acaggtctgg cacagattat ctctgccttg agtaatcact
     2161 ggtttggttt tcatattccg atttcgctaa gcttctacgc cattaacttc cctttgatgg
     2221 tcttagcttg gtatcagatt ggccataagt tcaccgtctt tacctttatc acggtatcta
     2281 tgagttcctt ctttatccag tttgtccctg tggcaacctt gacggaggat cccattatca
     2341 attccctttt tgggggtgtt gttatgggtt tggggattgg ttttgctctt cgaaacaata
     2401 tctccagtgg tgggacggat atcgtcagcc tgactattcg caagaaaacg ggtaagaatg
     2461 tcggtagtat ttctttcttg gtaaatggaa ctatcatgct gatagcaggt ttgacctttg
     2521 gttggaaata cgctctttat tctatgatta ccatctttgt ctctagccgt gtgacagacg
     2581 cagtctttac taagcaaaag cgtatgcagg ccatgattgt gacaaatcat ccagagaagg
     2641 taattgaaaa aatccataaa aaattgcacc gcggagcaac catgatccac gatgcagaag
     2701 gaacctataa tcacgagaga aaggcagttt taatcactgt cattacacgt gcagagttta
     2761 atgaatttaa acagattatg acacaagtgg atccaagctc ctttgtctct gtctcggaaa
     2821 atgttcatat tctaggaaga tttgttgaga tagataatta gtgattaata ctcttcgaaa
     2881 atctcttcaa accacgtcag cttcaccttg ccgtatatat gttactgact tcgtcagttc
     2941 tatctgcaac ctcaaaacca tgttttgagc tgacttcgtc agttctatct gcaacctcaa
     3001 aaccatgttt tgagctgact tcgtcagttc tatccacaac ctcaaaacag tgttttgagc
     3061 aacctgcggc tagcttccta gtttgcactt tgattttcat tgagtataaa aagatcttgg
     3121 gaaaagactc aatttcagta gaaaaggaag taaatcttcc cacaataaaa cgcatagtat
     3181 caagtttttt caatacctga tagtatgcgt ttttgctttt aacgactctt tgcccagtct
     3241 cttatttttc gataattttg tgggcgatca attgacggta acaaatttgt ttattgtttt
     3301 tattatcatt aataatctgg agaatagttt caagggaaac acgaccaagc tctaaactat
     3361 tgatatcgac ataggctgcc aagttgagct tgggattaac cgagtcaaag ctgagaacag
     3421 ggacatccag ctggtgtttg gcaatatagt tacaaacacc ttcagctagg aggctatcgg
     3481 ttgtgatgat agcatcaatt tgtggatcgt gcttgaataa tcgcttgcta aatttatagc
     3541 ccttttcttc cagaaactcg tcggcaaagt agatgcgatt gttgtcagtg gtaagtttgt
     3601 aatgtttaag cgcctgttca tagcctgtta aacggtcttt ggtcacgaag agctttttac
     3661 ttcctccgat aaaggcaatg cgtttgcagc cttttttgat gaaatattca gtcgcatcaa
     3721 aaccagcttg aacattgtcg ttgtcgacaa gtgggatgaa aggagataga gatttaccta
     3781 ggataaggaa ggggaactgt tcttctgcga cgagttttac gagagggtct tcttcttggg
     3841 catagagaaa gattagccca tctacacgct tgccgtagac catttgtgaa atagcgttga
     3901 gacgctcctt ctcatctttc cctgttgcta tctgaatggc atagtggttt tcagatgcga
     3961 cttgagagat gccacgtaga accgatggaa agaaaggatt ctggtagaag gcgtctgagt
     4021 catcaggaag aactaatccg ataacctgag tatagctgct taccaagcta cgagcgttga
     4081 ggtttgggtg gtagttgagt tccttcatag ccttgcgaac gcgttttttt gtttcgtcgc
     4141 taatggttga tttattttga ataacacggg ttacggttga aggcgaaaca ccagcagcct
     4201 tggccacgtc tttaatcgta acgggcataa aaatctccta tttatggtaa tttggatcac
     4261 ggaaatgtgt tttataaaag atagtgacca gatacagaac aaaaagaata ttttgtacag
     4321 taatcagggt tgtcatattt tggccaaata atcccaaaat aagtgtaatc agagtcggca
     4381 atcctaaaca gttcaagata aagtgatagc actctttaaa ggttctaaat gaaaagaggc
     4441 gtgatttctt agtgatataa aggagaagac tagctcctag agagacgata aagaaattca
     4501 aaccaaagag gaagctcgca ccgagaacta ggaagaggct gatatagaca cgattttgtt
     4561 ggtaccagtc tttagaaatt gcttgggtca agctgtcttt gcttttgaaa ctctcagtct
     4621 gaatggctcg gtaagagatg cgggtcagtt ccttgctttc cttgctgatg actagctcat
     4681 ttgtatcgaa atgcagttgc aagttcttag gtaattcctt gatttgactt ggaccaatca
     4741 caacagaaga ggcttgacta actgttccag tataagttaa tgtgccatcg acaattgtag
     4801 catgttcaga gagatcctgg acaacctcat ttgtcagagg ttcatagaca ttatcgataa
     4861 aagtttctag cggataggtc tcctgggagc tgttttggat agcaatgggt accatagaca
     4921 agctgataag gaagatactg gtaaagagaa gttgaaacca gttgagcccg aaacgtttgg
     4981 acaggggctt acgaaacccc aaaatacttg aaaaaaagga aaatggatat ggaagcatag
     5041 gtatctttct aaaaggtgtt ttctatataa gtattattat atagagaaat gcgctttatt
     5101 tcaagtctag gagaaaaatt gcttgctaca aggatattat ttacagtgac aattgctaat
     5161 aatcaatgaa aatcaaagtg caaactagcc acaggttgct caaagcacaa ctttgaggtt
     5221 ggagataaag ctgacgtggt ttgaagagat tttcgaagag tataaaatga aaaagggtgg
     5281 cggggataaa ttatcccttg tcgccaccac ttgtaagtcc tgaaacaaag ttcttttgta
     5341 ggaagaagaa gagaatacag attggaaggg cgatgaggat agcacctgct gagaagtagg
     5401 caatcttcaa gtttttcgca ttgttaacga aggtttggag acctacggca acagtaaagt
     5461 attctttctc acgaagcaag aaactagaga ggatgtagtc cccgaaaggt cccatgaagg
     5521 cccagagagc ttgtacggca accattgggc gaacaagtgg aagaacaatt tgccagaagc
     5581 ggcggaagtg tcctgcaccg tctagttttg cagattcgtc taaagacatt ggcactgtat
     5641 cgaagtagcc tttcatgagc caagcattca tcgggatacc accaccaacg tagaggaaga
     5701 tgaggaacca gttgtggtta agggcgttca acataagcgc cataacgaag aaggctgtca
     5761 aagcggccat agttggcacc atttggatga tcaagaagaa gaccaaactt tgtttacgag
     5821 ccaagaagtt gtaacggctg taagcataac cagcaagtac gatgatactt gtttgaacag
     5881 ccatggtaat taaggcgata atcaaagtgt tgaggtacca agtaccgtac aaggtttcag
     5941 tgaagaggcc tttaaagtta tcaaaattga ggtcgatatt agtatctagt ttaaaggctg
     6001 agacgttacc tgctttaaag gctgacataa tggtaatcaa cagtggatag ataattacaa
     6061 ttgatagacc aatcaggtaa aggtaagtaa ggctttgagt cagtctacgt ttgagtttaa
     6121 ttgagttatt catcttagac gtcctccata tcaaatgcgt gtagtttctt gaatgcgatc
     6181 atagagattg agatgacaat gatagagata atcaaggtaa cagctgccgc cattgagtat
     6241 tgaggagatg tacctgttgt caaacggtag atccatgaga tcaagatatc ggttgaacca
     6301 gctccacctc cgacactacc aggtcctcca ccattgaaga ggtacatgat agagaagttg
     6361 ttaaagttga aggtgtattg gctaatcaaa gtaggtgccg caacagccaa aatcattggg
     6421 aaagtgatgt tgcggaattt ttgccaagcg ttggcaccgt caatataagc tgcttcgtaa
     6481 aggtcgttag gaatagattg caagataccc aaggtcagaa cgtagatgta tgggaatccg
     6541 agccaacctt gcatcataat caaggcaatc ttagtccaag ttgggtctgt tttccaagga
     6601 ataagagctc catcaaggaa aggaaggaat ttagccaaga ttggcaatac ttgagtgttg
     6661 atagcaccga cactatcgtt aaacatgttt gagaatgtca agatagtgat gaaggctggg
     6721 acagcccaag gaagaaggaa aataacacca aagatacgtt ttcctttgat aaatggttgg
     6781 ttggcaatga tagctgtgaa gataccaatt acgatttgta aagtagaagc tgccaaagcc
     6841 caaatgatag tccaagaaag aacagaacca aaggcagaac ggaaggtact caagctccaa
     6901 atgtttgtaa agttggtcaa accaacccag tccaacaact tgtttggtgg caagtgttgg
     6961 aagtcgtagt tggtaaaggc gatcatcaag gttacgataa ctgggaagat aatcgcgaag
     7021 gtcatggcaa cataagatgg aatgatcaag aggtaaggga agccattttc ataaatccct
     7081 ttgatcatgt ctttgagtgt gcgtggaact ggaattccat tgttaatgcg ttttgcaatc
     7141 gtatgtgcat ctttgatatt tgagaaataa aagagtacat aaacgattac aaagattaga
     7201 tggaaggcac cacgaatcag cataaagagg gaattatcac gacctggttt gtcaccaaga
     7261 gtgatgaggt tgctcaattc aggggttgca agtgctagga agtaaaggac aaatacgatg
     7321 gttacaccaa ggaagataaa acctttggct ttttgtttat tgtaaatctg tcctaaccca
     7381 ggaatgatag acagcagggc tgctttacta ggttgttgct tttccatatt aactcctttc
     7441 ataggatact acttttttat aagaaagcta aattatttgt gtctctattg ataaattcaa
     7501 agggggattt gatttccacc ccccttgaac aaatttttta ttcaccaaat ttttgtttga
     7561 ttgtttcttt gatcaatgtt acagcatcgt tagcagctgt tttagcatct ttttgaccac
     7621 ttacagcatc aaagagcata tttttcgctg gatcccaaac tgcagacatt tgagagatgt
     7681 ttggcagtgg ttgagtgttc ttgaactgtt tgataacagc tgttgtcaac tcatcgtttt
     7741 taccttcagc gtatgaacga gcctcagtat tagctgggat ttcgttagtc ttatcatata
     7801 atactttttg ttgttcagtt gcaacaagga agtctacaaa tttttgagaa gcttcaaggt
     7861 tcttaacggc ttgaggaatg acccaagctt taccaccacc gaatgcagca tattcttttc
     7921 catttggaag agttgggata gttgcaactc cgtagtttac tttagcatct ttaaaggctt
     7981 gagctttcca aggtccgtcg atgatagcag ctgttttacc ttcttggaat tgagtttgga
     8041 ttaagtttcc agcaccttct gtatcttgca tacctttagg ccatttttcg taccaagatt
     8101 tagcgtagtt gatacctacg atagaaccgt cgtttgcaag accgatgtct ttagcgtctt
     8161 taccgttttg gccaaagacg taagcaccgt taccggcaag aagtccatat gtatagtaga
     8221 agtttgtcca gtcagctagg aaggcagtag ttttaccatc ttcaccagcg aatgcgtatt
     8281 tgctatcttt agcaaggttt tccaagtcag caaatgtttt tggagcatct ttcaccaagt
     8341 ctttgttgta gtacataaca agtgactcga taacggcagg agcaccgtaa actttaccat
     8401 tagcagctgt tacaagagat ttagttgtgt cgtctgtttt agcaccatcg ctcaatttca
     8461 cttctgaaag ttgtccgtca gaaccaaggc tacctacacg gtcgtatgga gccatcataa
     8521 catcagggac attaccagat tggttgtcaa gagaaagttt atcaagacct cctagagcat
     8581 caccagtttt aagagtgact tttactccag cttctttttc ataagcttta gcaacctctt
     8641 caatatagct cttatatccc tcgtctacat atacagtgag ttctttgact tcagatgaac
     8701 cagaatcagc aggcttatca gcagttttgc ttccgcaagc taccaaaagc aagctagcaa
     8761 gtgtaacagt tccaagcacc gcagtgctct tcataaattt agatgacata gtgtattcct
     8821 cccaaagaat agcaagtttt attgataagg aaacgcaaac gttttccttt atgagcttag
     8881 tatagcacaa atagaaaacg gttgcaagta ttttttgtaa aaattttaaa aaatttttaa
     8941 gcttgatttg atagcataat tttgcatttt aatagaagaa aagtatgaaa tagataagaa
     9001 tacagtattt ttaataaaaa tatatggaat ctgtctaaag agggaaacca ggaggggcta
     9061 cctccctggt tctaatccct atctattttc tatggacgtt tgtgctttgt tacatataaa
     9121 ttcaagctcc ctaaggaggt tttgtacttt gtagactgtc tcgtgagagt caaaccttag
     9181 gattagatag ttttaagtta tctttgctaa aatgagttag tctccttaaa aataatcaaa
     9241 aaagtttttt aaaaacgctt gcaattatgc ttgaaaagga gtatacttat aagtaacgca
     9301 aacgtttgcg tctgcaaaat acgcaacgtt ccattatttt aacacacgag gtgctattat
     9361 gaaaaaacgt caaagtggtg tgttgatgca catctcttct cttccaggag cttacggaat
     9421 cggatcattt ggtcaaagtg cttacgactt cgttgatttc ttggtccgta caaaacaacg
     9481 ttactggcaa atccttccat taggagcaac tagttacggg gattctcctt accaatcttt
     9541 ctcagccttc gcaggaaaca ctcattttat cgatttagat atcttggtgg agcaaggttt
     9601 gttggaagca agtgaccttg aaggagttga ctttggtagc gatgcgtctg aagttgacta
     9661 tgctaaaatc tactatgcac gtcgtcctct tttagaaaaa gcggtgaaac gtttctttga
     9721 agtcggagat gttaaagatt ttgagaaatt tgctcaagac aaccaatcat ggcttgagct
     9781 ctttgctgag tatatggcta tcaaagagta ttttgacaat cttgcttgga ctgaatggcc
     9841 agatgcagat gctcgtgctc gtaaagcttc agcacttgaa agctatcgtg agcaattggc
     9901 agacaagttg gtttaccacc gtgtgactca atacttcttc ttccaacaat ggttgaaatt
     9961 gaaagcttac gctaacgaca accacatcga aatcgttggg gacatgccaa tctacgtagc
    10021 ggaagattca agtgatatgt gggcaaatcc acatctcttc aaaacagatg tcaatggtaa
    10081 ggctacttgt atcgcaggat gcccaccaga tgagttttct gtaactggtc agctttgggg
    10141 taacccaatc tatgactggg aagcaatgga caaagacggc tacaaatggt ggattgaacg
    10201 cttgcgtgaa agcttcaaaa tctacgatat cgttcgtatc gaccacttcc gtggcttcga
    10261 atcttactgg gaaatccctg ctggttccga tacagcagca cctggtgagt gggtgaaagg
    10321 tccaggctac aagctttttg cagccgttaa ggaagaactt ggtgagctaa acatcatcgc
    10381 agaagacctt ggcttcatga cagatgaagt gatcgaattg cgtgaacgta ctggcttccc
    10441 aggaatgaag attcttcaat ttgccttcaa cccagaagac gaaagcattg atagcccaca
    10501 cttggcacct gctaactcag ttatgtacac aggaacacac gataacaata cggttcttgg
    10561 ttggtaccgt aatgagattg atgatgcgac tcgtgagtac atggctcgtt acacgaaccg
    10621 taaagaatac gaaacagtgg tacacgctat gcttcgtaca gtattttcat cagttagctt
    10681 tatggcaatt gcaactatgc aagatttact agaattggat gaggcagctc gtatgaactt
    10741 cccatctacc cttggtggaa actggtcttg gcgtatgact gaagatcaat tgacaccagc
    10801 tgtcgaggaa ggtttgcttg acttgacaac aatttatcgc cgaattaatg aaaatttggt
    10861 agatttaaag aaataagaca ataatcagga gacaactaaa catgttatca ctacaagaat
    10921 ttgtacaaaa tcgttacaat aaaaccattg cagaatgtag caatgaagag ctttaccttg
    10981 ctcttcttaa ctacagcaag cttgcaagca gccaaaaacc agtcaacact ggtaagaaaa
    11041 aagtttacta catctcagct gagttcttga ttggtaaact cttgtcaaac aacttgatta
    11101 accttggtct ttacgacgat gttaaaaaag aacttgcagc tgcaggtaaa gacttgatcg
    11161 aagttgaaga agttgaattg gaaccatctc ttggtaatgg tggtttggga cgtttggctg
    11221 cctgctttat cgactcaatt gctactcttg gtttgaatgg tgacggtgtt ggtcttaact
    11281 accactttgg tcttttccaa caagttctta aaaacaacca acaagaaaca attccaaatg
    11341 catggttgac agagcaaaac tggttggttc gctcaagccg tagctaccaa gtaccatttg
    11401 cagactttac tttgacatca actctttacg atattgatgt tactggttat gaaacagcga
    11461 ctaaaaaccg cttgcgtttg tttgacttgg attcagttga ttcttctatt attaaagatg
    11521 gtatcaactt tgacaagaca gatatcgctc gcaacttaac tctcttcctt tacccagatg
    11581 atagtgaccg tcaaggtgaa ttgctccgta tcttccaaca atacttcatg gtttcaaacg
    11641 gtgcgcaatt gatcatcgac gaagcaatcg aaaaaggaag caacttgcat gaccttgctg
    11701 actacgcagt tgtccaaatc aacgatactc acccatcaat ggtgattcct gaattgattc
    11761 gtcttttgac tgcacgtggt atcgatcttg acgaagcaat ctcaattgtt cgtagcatga
    11821 ctgcctacac taaccacaca atccttgctg aagcgcttga aaaatggcct cttgaattct
    11881 tgcaagaagt ggttcctcac ttggtaccaa tcatcgaaga attggaccgt cgtgtgaagg
    11941 cagagtacaa agatccagct gttcaaatca tcgatgagag cggacgtgtt cacatggctc
    12001 acatggatat ccactacgga tacagtgtta acggggttgc agcactccat actgaaatct
    12061 tgaaaaattc tgagttgaaa gccttctacg acctttaccc agaaaagttc aacaacaaaa
    12121 caaacggtat cactttccgt cgttggctta tgcatgctaa cccaagattg tctcactact
    12181 tggatgagat tcttggagat ggttggcacc atgaagcaga tgagcttgaa aaactgttgt
    12241 cttatgaaga caaagcagct gtcaaagaaa aattggaaag catcaaggct cacaacaaac
    12301 gtaaattggc tcgtcacttg aaagaacacc aaggtgtgga aatcaatcca aattctatct
    12361 ttgatatcca aatcaaacgt cttcacgagt acaaacgcca acaaatgaac gctttgtacg
    12421 tgatccacaa ataccttgac atcaaagctg gtaacatccc tgctcgtcca atcacaatct
    12481 tctttggtgg taaagcagct ccagcctaca caatcgctca agacattatc catttaatcc
    12541 tttgcatgtc agaagttatt gctaacgatc cagcagtagc tccacacttg caagtagtta
    12601 tggttgaaaa ctacaacgtt actgcagcaa gtttccttat cccagcatgt gatatctcag
    12661 aacaaatttc acttgcttct aaagaagctt caggtactgg taacatgaaa ttcatgttga
    12721 acggagcttt gacacttggt actatggacg gtgctaacgt ggaaatcgct gagttggttg
    12781 gagaagaaaa catctacatc ttcggtgaag attcagaaac tgttatcgac ctttacgcaa
    12841 aagcagctta caaatcaagc gaattctacg ctcgtgaagc tatcaaacca ttggttgact
    12901 tcatcgttag tgatgcagtt cttgcagctg gaaacaaaga gcgcttggaa cgtctttaca
    12961 atgaattgat caacaaagac tggttcatga ctcttcttga cttggaagac tacatcaaag
    13021 tcaaagagca aatgcttgct gactacgaag accgtgacgc atggttggat aaagtcatcg
    13081 ttaacatttc taaagcagga ttcttctcat ctgaccgtac aatcgctcag tataatgaag
    13141 acatctggca cttgaactaa tactcttcga aaatctcttc aaaccacgtc agctttatct
    13201 gcaacctcaa agcggtgctt tgagcaacct gcggctagct tcctagtttg ctctttgatt
    13261 ttcattgagt ataagataca aatttatact aatacatttt gtaaaaaagc gagtttcgat
    13321 tgaaattcgc ttttttaaat gctgtggatt tgggtcaatc ttgtctaaaa atagggaaat
    13381 cctagataca gtgaaggctt taaatgctgg tttttactgt cttcagcctt atattttttc
    13441 gtagttggtt acctcatatc tcttgtattc gcttacataa agtattataa tataattgta
    13501 ggaaagaagg tgtttttatg atatacacac ttaaattggt gttgtttatt acctttcttg
    13561 taataagctt gttacctgat aagatttttg gaaaaaataa aaaaatttgg aaaatagttt
    13621 ttgcaatatt gacggcagtg gcagcattgt catttatgta ctaagttatt ttaagaatgt
    13681 agggaaataa accctacatt tttttagttt tttctgtttt ctaaattcta tttatccaag
    13741 agcttcaaca tttcttgctt cttcgcttca agttctgcac gcttttcttc gatttcggca
    13801 tgttttttct cgagttcaga acaacttgca tcattgctaa attcttttcg ccatcaggag
    13861 atagggtgag tctacatgtc tattactcac ccaaagcagt cctacaaagc aggaattttc
    13921 tgttactttt ttggaaatag taacgtttat acagctttga cacttcgtat caaagcgcca
    13981 aacacactcc gagggattta cagaaagcag aaaaggaatg atctggtata agatcattcc
    14041 ttttctctct ttttctttaa gtaattatat acaatgtacg acgaagtcgt cattgcaatg
    14101 ctgatccacc acctaaaggg aactttaaac aacattgata agataaagaa tataaacaac
    14161 gaaaatacgt tatacccaat taattttatt gtatatctca tgattaaaag ttaatccttc
    14221 cgttgttagg aatggcatca tttttatccc ataattgtgc taaataagtc cccggtgata
    14281 ataaattcat agcgaattct aaagcaacat catttacaaa ccaactacct agatatctag
    14341 aaattgctga acgaatagca ctttttgctg catgttttcc ttttacttta attagatttg
    14401 caaggcctgc agtagttcct cctaatgcta aagctattgc agtatctaat agagcaccca
    14461 tttgattaac tgtaatacct tgccaagctg ctctaaatgg agagtatgta ggtgggattg
    14521 tataatcgcc ttgtaattgt cggttaatta cttctttgat ccattgttgt gagacgtctg
    14581 gatgaaaaga ttggatttcg tttgcaagtg tattgatttg ttcttctgtt agagaagtga
    14641 caggttgaag ttccatattt gtttcaattt gtgatacttg ttcagaagcg tatacagctg
    14701 aaacacttgg aatcgctgat acaattaaca caattgacgt caaaaaaacc gaaataaatt
    14761 tcattaattt gttcatgagc ttttctcctt tttatttgta tctgcttaca ttttatcata
    14821 tactgttatt atagtcaaaa aaatatgcta ttatgttaaa aaaatatttt tcaaaatata
    14881 aatggacgga tttattttgg attttatttg ttattttgac ctgcctctat attggtaacc
    14941 atgatttgtt tactctcaat catcaagaat tctcttttcg tggtagcgtt tggggtctgg
    15001 tactggcctt atatcactta ttgttcattg ataagtttgt aatttcgaat cgaaaataaa
    15061 gattagaact atgattgact ggctactttt aatattgatt ttggaggaag attttgtctc
    15121 tattatttat tattttaaat ttatctattt tgtacaagat ttattctttg agacgggaga
    15181 aatcgaaata cttgatttat acggcctata tcatatttgg ggtaaatgta gtatatggta
    15241 ttcaatggtt attaagagaa ctgatttcaa ctatttcccc ttaatgtgta tggaaactat
    15301 aacaaaacgc ataagattaa ggtttgtgta cctgttctta tgcgttttta taatattgaa
    15361 gattttcggt aagttttata cctttgggaa gtctagttta gaatgctttc ccaaccaaaa
    15421 tctctgcttc gatggtaatc tctgtcagtt ggctccagtc aatcttgctc tggtcaacgt
    15481 gaaagaggag aggagtcata ctgagtaggg cttggagttg ttctgctgtg atagtcttag
    15541 tcagagaggc agtttgacta gataggatgg taaagtgttc ctggaaatgc tccttgatat
    15601 cttggttaga atactccttg tttgtcagct ggtcctgtac tctttgacgg atttctttga
    15661 ggtgattttc agttgggata acctttatca agataccgtc tttggataaa acgcgacgaa
    15721 attctccata gttggcaggt gagaagatat caagcagaat atccatgtta gcgtctttta
    15781 taggaagtcg tgccaagtcg ccaacaaacc aattgactgc ccagttgggt tcacttttag
    15841 cagcgatttg gactgaatct ttggagatgt caaaggcata gaaagttttt tcagagtgac
    15901 tttcttgtag tttgcgagaa tagaatcctt caccacaacc gatatccaaa attgttgtgg
    15961 tagtttttga gcttgcaagc aagtcagata cagcatctaa gatagcttgg taaaagccgg
    16021 cttctaggat ttgttgacgg ttttgaaaat tttccttgtt atagttagca gattgcttga
    16081 tttgaggtgc tagattgaca tagccaaatt tcgccaagtc aaaagaatga cggttgcagc
    16141 acttgaaatt agtctctaac agagtcagat tttcttgaca gataggacag gcaaaggcag
    16201 tcgcagaagc aaaacgctga agtttgggct tgagatttgt attcatagtt taagtgtatc
    16261 aaaagaggca aatgaaagca actttaggaa taagtagatg ggagattcag tagaaataaa
    16321 actaattctc caatttatag aatgaaattg cttttatatc taaattgcta tataataatg
    16381 ataaggagga aataagtatg ttaaaagaag tattaaccgt tgcaaaagtt gcgaaaaaat
    16441 cttcattatt tttgggtggt gtcgcatttg gtacccttgg tttgaaaatc ttagcaagta
    16501 aggaagctaa aaaaggttat tctaaagctt tggctaaggc ttacaagttg aaagacgagc
    16561 tagatgcatc tgtttctgtt gtgaagcaac atggagacga tgtcttgcaa gatgccaaat
    16621 atttgtacga gcaagagaaa aaagaagagc aattagatag ccttataggt gaataatatg
    16681 tcttttaaag tgctacatag aggataccaa catatccgac tatcatcttc tttttcactt
    16741 accttggata ttcaagacta tcttcgttcc ttggcgagag atgaaaaggg gattgagtct
    16801 atccagtttt acatggatca acagcacttt actctacgca taaaagaagg cttttctgta
    16861 ttagataatg cagaagcctt tttaaaaaga attgataaag ggaaagtttc tgagttgatg
    16921 actcttccca ttcgtagaga agagagtgct tattctattg tttcaggtgc agcggttaag
    16981 cgtgtacttt ttcgtagttt tgtgccgtat cctattcgct atatatggac ttgttatcag
    17041 gctttgggtt atattagaga agcctatcaa acactagcgc gtaaggaact aacgatggaa
    17101 gtcttggact gttcggctat tttattgtct ttgtttatga accaatccaa gacagctagc
    17161 aatatcatgt ttatgcttga tttggggaat catttagatc agtggtcctt gaaaaaaact
    17221 gcaacagatt tagaacagag tcttcttgca aaagagagcg atgtattcct agtacagggc
    17281 gatacggttg ttagtatcaa gagttccgat gttcaaatag gagatgtctt gatcttatct
    17341 caaggaaatg aaattctgtt tgatggacaa gtagtttcag gtttaggtat ggtcaacgaa
    17401 agttccttga caggagagag ttttccagtt gaaaaaagag agtctgattt ggtttgtgca
    17461 aatacagtat tagaaactgg agagttacgc attcgtgtaa cagataatca gatgaacagc
    17521 cgtattttac agctgattga gttgatgaag aaatctgaag aaaacaagaa aacgaaacaa
    17581 cgctatttca tcaagatggc ggataaagtc gtcaaatata atttcttggg ggctgggctg
    17641 acttacctat tgacaggttc tttttctaag gctatttctt tcctattggt cgatttctcc
    17701 tgcgctttga aaatctctac tcctgtagct tatttgacag ttatcaagga agggttgaac
    17761 cgtgaaatgg tgattaagga tggagatgtt ctggagaaat atctggaagt tgatactttc
    17821 ttgtttgata agacaggaac aatcacaact agttatccta tagttgaaaa ggtgttacct
    17881 tttggagact atagtgagga agatattctc agaatcagtg cctgtcttga ggaacacatt
    17941 tatcatccta ttgctaatgc catcgtcaag caagctgaga tagagggaat tgaacatgag
    18001 gaaatgcatg ggaaactcca atatatcgca agcaagggga tcaaatctca tatagatggc
    18061 caaccagttc ttattgggaa ttatgtcttg atgcaggatg agcagattca tatcagttca
    18121 gaacaaaatg ctttaattga agagtacaag agtcactaca atctcttatt cttggcttat
    18181 caaaatgaat tgattggaat gttctgcatt catactcctt tgagaaaaga agcaaaaaca
    18241 gccttggata aacttaaggc acaggggaaa aaattgattc tggcaacagg ggacaccttg
    18301 gttaggacaa aggaattagt caaagatttg ccctttgatc aggtctatac agacttgaaa
    18361 cctgatggga aatttgagtt agtagagaaa ctgcagaaag caggtcacac tattttgatg
    18421 gttggagatg gattgaatga ctcagcggct ttaactctat cagatatcgg tgtggtgatg
    18481 aatgagagtg cagatatttc taagcagatg agtgatatct tattgttaga taatcgtttg
    18541 gatttcttcc aagagttgga ttcgttatca tcatctttgc aaacactcat caagaaaaat
    18601 attcaagata ccgttgtcgt aaatagtagt ttgattggct tcggcttatt taattggctc
    18661 agtccttcaa atctctctat cttacataat ctaacaacct tgcgcattgt cctgcgtagc
    18721 ctgtctatta aaaatagata gatgagagtt attaacagca aaaaggagtt acctttctcg
    18781 aggttaactc ctttgtttat agataaatgt tgaatagttt agtaagtcaa tacaaagtat
    18841 tttttcttcc cacgacggat aacagtcagt tcattctcta acttatcagc gtcactcaag
    18901 acatagtcaa gctcttggat gcggtcgccg tttacgtaga tggctccgtt ttggacgtct
    18961 tcacgggctt ggcgttttga gttaactata ccagatgaga cgagcagttc cacgatattg
    19021 ttgttttcgt ctgcctgtac ttggtagttt ggcacaccac gaagtccttg tttgagctct
    19081 ttgacagaaa ggtttttgat gtttcctgca aagagttgct cagtgatgtt aagtgcttct
    19141 ttgtaggctt cttctccgtg aacaagtgta acaacttcac gagccaagac tttttgagcc
    19201 aagcgttcgt gtggcgctgc ttcaaattgt ttacgaatat cttcaatctc atcaagtgac
    19261 aagaaagtaa agattttcaa gaagcgaaca gcgtcagcgt ccatcacgtt catccagaat
    19321 tggtacattt cgtatggaga agtcttttcg ggattgagcc agacggcatt tccttctgat
    19381 ttaccaaatt tcttaccagt tgcatctgtg attagtggaa cagtgataac gtgaccagtc
    19441 ttgtccgcct tacgacgaag caattcggta ccagctgtca tatttcccca ctggtcagaa
    19501 ccaccgattt gaagagtgac attatggtct tggttaagga cgaagaagtc atacccttgc
    19561 atgatttggt aagcgaactc agtgtaagaa attcctgttt cgatccgttt tttaacagat
    19621 tccttactca tcatgtagtt gaccgtgaag tattttccaa tatcacggag gaagtcaatg
    19681 aagctgatgc tgccaaacca gtcgtagttg ttgaccatga cagccttgtt ttcgccattt
    19741 tcaaagtcaa gaaaacgaga aagttgtcct tggatagact tgacccagcc atctactgtg
    19801 tcttttgttt ggagactacg ttcagcatct ttgaaggacg gatctccgat gagacctgta
    19861 gcaccgccaa cgagcgcata aggtttgtga cctgctagtt gcaagcgacg acttgtcaag
    19921 attgcgacaa ggtggcctag gtgaaggctg tcagcagttg gatcgtagcc agtataataa
    19981 gaaacttgac cttcttctag ggctttacgc aaagcttctt catcagtcgt ttgaaatatc
    20041 aaaccacgct cttttagctc atcaaaaatg tgcatgtgtt ttttctcctt tttaaaatta
    20101 ttgtttctac ctattgtatc acaaacttgg gcaatagcct agcagaatag ggaagaaagt
    20161 ggctatttta ttgaaaattt cccttttgtg gtataataga taaagtgagg aaatccatgc
    20221 aaaatcaatt aaatgaatta aaacgaaaaa tgctggaatt tttccagcaa aaacaaaaaa
    20281 ataaaaaatc agctagacct ggcaagaaag gttcaagtac caaaaaatct aaaaccttag
    20341 ataagtcagc cattttccca gctattttac tgagtataaa agccttattt aacttactct
    20401 ttgtactcgg ttttctagga ggaatgttgg gagctgggat tgctttgggg tacggagtgg
    20461 ccttatttga caaggttcgg gtgcctcaga cagaagaatt ggtgaatcag gtcaaggaca
    20521 tctcttctat ttcagagatt acctattcgg acgggacggt gattgcttcc atagagagtg
    20581 atttgttgcg cacttctatc tcatctgagc aaatttcgga aaatctgaag aaggctatca
    20641 ttgcgacaga agatgaacac tttaaagaac ataagggtgt agtacccaag gcggtgattc
    20701 gtgcgacctt ggggaaattt gtaggtttgg gttcctctag tgggggttca accttgaccc
    20761 agcaactaat taaacagcag gtggttgggg atgcgccgac cttggctcgt aaggcggcag
    20821 agattgtgga tgctcttgcc ttggaacgcg ccatgaataa agatgagatt ttaacgacct
    20881 atctcaatgt ggctcccttt ggccgaaata ataagggaca gaatattgca ggggctcggc
    20941 aagcagctga gggaattttc ggtgtagatg ccagtcagtt gactgttcct caagcagcat
    21001 ttttagcagg acttccacag agtcccatta cttactctcc ttatgaaaat actggggagt
    21061 tgaagagtga tgaagaccta gaaattggct taagacgggc taaggcagtt ctttacagta
    21121 tgtatcgtac aggtgcatta agcaaagacg agtattctca gtacaaggat tatgacctta
    21181 aacaggactt tttaccatcg ggcacggtta caggaatttc acgagactat ttatacttta
    21241 caactttggc agaagctcaa gaacgtatgt atgactatct agctcagaga gacaatgtct
    21301 ccgctaagga gttgaaaaat gaggcaactc agaagtttta tcgagatttg gcagccaagg
    21361 aaattgaaaa tggtggttat aagattacta ctaccataga tcagaaaatt cattctgcca
    21421 tgcaaagtgc ggttgctgat tatggctatc ttttagacga tggaacaggt cgtgtagaag
    21481 tagggaatgt cttgatggac aaccaaacag gtgctattct aggctttgta ggtggtcgta
    21541 attatcaaga aaatcaaaat aatcatgcct ttgataccaa acgttcgcca gcttctacta
    21601 ccaagccctt gctggcctac ggtattgcta ttgaccaggg cttgatggga agtgaaacga
    21661 ttctatctaa ctatccaaca aactttgcta atggcaatcc gattatgtat gctaatagca
    21721 agggaacagg aatgatgacc ttgggagaag ctctgaacta ttcatggaat atccctgctt
    21781 actggaccta tcgtatgctc cgtgaaaagg gtgttgatgt caagggttat atggaaaaga
    21841 tgggttacga gattcctgag tacggtattg agagcttgcc aatgggtggt ggtattgaag
    21901 tcacagttgc ccagcatacc aatggctatc agaccttagc taataatgga gtttatcatc
    21961 agaagcatgt gatttcaaag attgaagcag cagatggtag agtggtgtat gagtatcagg
    22021 ataaaccggt tcaagtctat tcaaaagcta ctgcgacgat tatgcaggga ttgctacgag
    22081 aagttctatc ctctcgtgtg acaacaacct tcaagtctaa cctgacttct ttaaatccta
    22141 ctctggctaa tgcagattgg attgggaaga ctggtacaac caaccaagac gaaaatatgt
    22201 ggctcatgct ttcgacacct agattaaccc taggtggctg gattgggcat gatgataatc
    22261 attcattgtc acgtagagca ggttattcta ataactctaa ttacatggct catctggtaa
    22321 atgcgattca gcaagcttcc ccaagcattt gggggaacga gcgctttgct ttagatccta
    22381 gtgtagtgaa atcggaagtc ttgaaatcaa caggtcaaaa accagggaag gtttctgttg
    22441 aaggaaaaga ggtagaagtc acaggttcga ctgttaccag ctattgggct aataagtcag
    22501 gagcgccagc gacaagttat cgctttgcta ttggcggaag tgatgcggat tatcagaatg
    22561 cttggtctag tattgtgggg agtctaccaa ctccatccag ctccagcagt tcaagtagta
    22621 gttctagcga tagcagtaac tcaagtacta cacgaccttc ttcttcaagg gcgagacgat
    22681 aattctctaa atgaagtggc caatcaatgg attgccactt ttttcttttc gtgttacaat
    22741 aagggtatga atcagtatca gaaaaagatt gttaacggaa aaatttattc gctcctatcc
    22801 ggcttaatat ggggaatctg tggaatttta ggagagtact tctttactca ttatcaggtg
    22861 tcttcgggct ggattacctc tatgcgtttg acactggcag ggagtcttgt actcatttgg
    22921 tctgcaatac aattaaaatc gcaagtgcta gatatttggc gagacaagaa aaattacctg
    22981 ccctttttag cctatgctat tttggggatt ttttcagttc agtatttttt ctatctctgt
    23041 gtagaatact caaatgctac gacagcaact attttacagt ttattagccc tgtctttatc
    23101 ctcttttaca atcgcttggt ttatcaaaaa cgagcgtcaa aaagcgctgt tttctatgtt
    23161 ttggttgcca tgctgggtgt ttgcttgatg gcgacaaagg gagacctctc tcagttatcc
    23221 atgacgccgc tagctcttat aacaggtttg ctgagtgcca tgggtgttat gtttaatgtt
    23281 atcttgcccc aaccttttgc taagcgttat ggttttgttc ctacggttgg gtgggggatg
    23341 attttggcag gtttgtttag caatgtcctc tcgccggttt atcagctttc ctttactctt
    23401 gatatttgga gtatcttgat ttgcctcatt atcgctttct ttggaacggc ttttgctttt
    23461 ttcatttcca tgaaggctgt gtccttggtt tctcctttgg tggttgccgt tatcagtgcc
    23521 agtgaacctc tctcttctgc tctcttgagt gttttgttct taggattagt agtggattgg
    23581 tccctccttc tagctatagc cttgattatt ttacccatga tatttttgtc tatagaagaa
    23641 gcgaaagaaa gtagataaaa agtcttttct taattctaaa agtgtgctat actagaatag
    23701 tcaataaaac acggggagat agttgtgaag agtgttttta ggttgtatcg gtaggggctt
    23761 gcttttaccg acagcacgtt ttatctcaca tccctaaaaa atcataccta aaaacagaca
    23821 aaaaggtttc aaatttgagg ccttttttgg tagaataggt atcattataa cgaaccagga
    23881 ggcacctatg actgctacaa aaatgaacgc tcaagaaatt atccaattta tcgccaatgc
    23941 tgaaaagaaa accagtgtca aagtaacctt tgaggggcaa ctcgcaactg ctgtgcctag
    24001 ctctgttgtc aaactaggaa atgtcctatt cggagactgg aaggacgtgg ctccgcttct
    24061 tgaaggtttg gtagaaaatc aagattatgt tgtcgagcaa gatgctcgta attctgcagt
    24121 tcctttgcta gataagcgtg ctatcaacgc tcgtatcgag ccaggtgcta ttatccgtga
    24181 ccaggtggaa attggtgaca atgctgttat catgatggga gctgttatca atatcggtgc
    24241 tgaaatcggt gctggaacca tgattgacat gggtgccatc cttggtggcc gtgccatcgt
    24301 tggaaaaaat agccacgttg gtgcaggtgc agttttggca ggtgtgattg agccagctag
    24361 tgctgaacca gtccgtgtcg gagacaatgt tctcatcggg gctaatgcag tggttatcga
    24421 aggagtccaa atcggtagtg gttcagttgt cgcagcagga gctattgtta cccaagatgt
    24481 cccagaaaac gtggtagtag caggtgttcc agctcgtatt atcaaagaaa ttgatgccca
    24541 aactcaacaa aaaacagcgc tagaggatgc gcttcgtacc ttgtaattgt aaaagtaaaa
    24601 aagaggcgga accctttttc cagcctcttt ctgctatatc ggaggacaga tagatgttag
    24661 atttgattca gactagacga gatttacacc agattccaga gattggcttg gaggagttca
    24721 agactcaggc ttatttgctg gatgtgattg agaaattgac tacgggcaag gattttgttc
    24781 aaattcgtac ttggcggaca gggattttgg tctacctgca gggaagtcag ccggagcgaa
    24841 ccattggttg gcggacagat attgatggcc tgcctatcgt cgaacaaaca ggtctacctt
    24901 ttgcttctca acaccaaggt cgcatgcatg cctgtggcca tgattttcat atgaccattg
    24961 ccttaggctg tcttgagcgc gcccttgagg agcaacccaa gaataatctg ctctttctat
    25021 ttcagcctgc tgaagaaaat gaagctggtg gtatgctcat gtatgaggac gatgcttttg
    25081 gagattggtt gccagatcaa ttttatggcc tccatgtccg tccagatttg aaagtcggcc
    25141 agattgcgac taatactcat acactctttg caggaacttg cgaggtgaag atccgtttca
    25201 aaggcaaagg tggccacgca gcttttcctc atgaagccaa tgacgccttg gtggcggcta
    25261 gttactttgt gacccaagtg cagtcagttg ttagccgcaa tgtcaaccca atcgagggag
    25321 cagtggtgac cttcggcgtt tttcaagctg gaaccaccaa caatgtcatc acagacacag
    25381 cttttttaca tggaactatt cgtgccttga cacaggacat gagtctcttg gtgcaaaaga
    25441 gggtaaaaac agttgcagaa ggggttgcag ctgcctttga tatggaagtc gaagtggaac
    25501 tcaaacaagg tggataccta cctgttgaga acaatccagc cttggcgcgt gaactgatgg
    25561 acttctttga cgaaaaagac ggaatcgagt tgattgatat cgaacctgct atgacaggcg
    25621 aggactttgg ttatctcctt tcaaaggttg atggcgtgat gttttggcta ggtatcgata
    25681 gtccctacgc tcttcatcac cctcaaatga gtcctaagga agaagtctta gctattgggg
    25741 tggctgcggt gtctagtttc ctgaaaaaga aggcagcaga atagagggct tgtctatgaa
    25801 atcggaatta cgcaagcaag tcttgcatga aatgaaggct atatctcaag agcaaaaaca
    25861 ggctatagac caagctttaa ccgagcgaat tttacaacac cccttttatc aagaagccaa
    25921 ggtcatcgca acctacctct ctttttctca tgagtttcaa acgcgggaac tgattgagca
    25981 ggcgctgaag gacggcaaga aggttttaat acccaaaact tatcccaagg ggcgcatgga
    26041 ctttgtagtc tatgatccgc agcagttggt aaaaactgcc tttgccttac tggagccaca
    26101 gggagatttg gaagtggtgg atgcatctca gattgatttg attcatgttc ctggcctggc
    26161 ttttacgacg gatggatatc ggattggata tggtggaggt tattatgacc gctatctgga
    26221 acatttttct ggtcatactt tgagtacggt tcatccttgt caaattcagg actttatacc
    26281 tgaaaaccat gatattcctg ttcaggaggt attaattgat gaaggaaatc tttgatagac
    26341 gttaccctgt gacgagtttc ttcctcttag tgacggcctt ggtattttta ctaatgttgg
    26401 tcactgcagg cggaaacttt gacagggcag atacattatt tcgatttgga gccatgtatg
    26461 ggccagctat tcgcctcttt cccgagcagg tttggcgtct cttgtctgcc atttttgttc
    26521 atattgggtg ggaacatttc attgttaata tgctttcact ttattatctt ggaaggcagg
    26581 tagaggagat tttcggttct aagcagtttt tctttctcta tcttttatca ggaatgatgg
    26641 gcaatctctt tgtttttgta tttagtccta aatccttagc agcaggcgcc tctacctctc
    26701 tttatgggct atttgccgcg attattgttc ttcgctatgc aactcgcaat ccttatatcc
    26761 aacagctagg gcaatcctat ctgacacttt ttgtggttaa cattattgga agtgttctga
    26821 ttccaggaat cagcctagca ggccatatcg gtggtgcagt tggtggcgca tttctagcag
    26881 ttatctttcc agttagagga gaaaaacgga tgtataacac cagccagaga ttaggagcgg
    26941 tagtcttgtt cgtaggactc gccattttgc ttttctacaa gggaatggga atgtgacgaa
    27001 gttgaaagaa aatttgtgta atgaaaaaag ataaggcatt ttttgaacct tatcttttta
    27061 ttttatttta ttccttctca gtcaattctt ttccaagttg gatgaggtaa ttcttcaaat
    27121 catctttgac ttgtgggtgt ttgagggcgt agtcgatgga tgttttcatg aagccaaact
    27181 tgtctccgac atcgtaacga gccccattga actcacgagc aaatacacgt tgtgttttat
    27241 tgagggtgtc gattgcatct gtcagctgaa tttcatttcc tgcacctgga gcttggtttt
    27301 cgaggatttg gaaaatttca ggcgtgagga ggtagcgtcc gataatagca aggtcgctag
    27361 gagcgtcctc tggagctggt ttttcaacaa aggtttcaac actgtaaaga ccatcttttc
    27421 cttcgccttg cggagcaata accccgtaag cagatacttc gtcatgaggg actggcatga
    27481 cagcgatagt agacgcgtgg gtacgctcgt agtcatccat gagttgtttg gtaagtggaa
    27541 cagccttttc gtctgtgata tccatcaagt catcaccaag cataacgaca aaaggttcat
    27601 ttccgacgaa agccttggct tgcaaaacag catctccgag accgcgtgga tgagtttggc
    27661 ggataaaatg cagccgcatg tcagttgttt tatcaactag cttcaaaaga tctgttttcc
    27721 ctttttcttt gaggttatat tccaattcga agtttgaatc gaagtggtcc tcaatagaac
    27781 gttttgattt accagtgaca actagaatat cttcaatacc tgatttgaga gcctcttcca
    27841 cgataaactg gatagttggt ttgtctacga ttggcaacat ttctttggca agggccttgg
    27901 ttgctggtaa aaatcgagtt cctagtccag cagcagggat aactgccttt ctaacttttg
    27961 atgtcataaa aatcctttct atagagggtt aagaccactc attttctgct ttaaattcat
    28021 tgttcatgat gtcataaatg gcatctttga tattggttcc gtgataaata acttggtaaa
    28081 tagcctgtgt aatgggcata tagactccaa gttcttgggc tagttcatag gctgctcgag
    28141 tcgttgaaat tccttcgatt accatgccca tattagcttc tatatcagct agggattctc
    28201 ctcgtccgag agcatctcca gctctccagt tacgagagtg gatggaagtt cccgttacga
    28261 tcaaatctcc cacaccagat aagccgctat aggtcaatgg actggccccg agtgctaccc
    28321 ctaggcgggt gatttctgct aaacctcgag cgatgatggc tgccttagca ttatcaccaa
    28381 atccaagacc atgtaaagct ccagcaccga cagcaataat atttttaaga gcaccagcag
    28441 tttcaacccc gataacatcc gtattggtat aaagtcggaa gtagtgatta ctaaatagct
    28501 cctgaacgta ttgagctgtt tgtaaatctt tagaagcagc agttattaaa gttaggtcac
    28561 gcacaatggt ctcttctgca tgactaggcc ctgaaacaac gacgatatca ctacggagat
    28621 gttcaggaat ttcttcttca agaatggttg ataatcgttt atggctatca ggttctaatc
    28681 cctttgatgc gtgcatgatg ataaccttat ggtccaaggt ttgtgcaact tgctgggcaa
    28741 caagtcgtgt cacttttgtt gggacaacaa acaaaatcgc atccacattt ttcaatgttt
    28801 ctgctaagtc ggtgtaggca atgatatttt cgtctagaac gacatcttta aagtagtgct
    28861 tattagtatg gtgtgtatta atttcattga tttgctcggg aagatttccc caaatacgta
    28921 cctcgtgtcc attgtcattt aagacttgtg aaagggcggt tccccaagaa ccaggcccca
    28981 agacggcgac ggtttgtttt tccatgattt cctccttgat agatttcttt ctcttattct
    29041 atcatattct aggggatttt gcacttgcat tactggggta tggtggaaaa atacacaaag
    29101 accgagatga agggataaac tcttagtctt tagttaaagt gagaagaaat ctgatagata
    29161 gtttgattca gtatatgctt ataatagagg taaacaactc aggaagttct tgtaggttgc
    29221 gagagtttgg cgaaaaaatt aaaagattac gtttggctaa aaaaatcagt cgttcagaat
    29281 tttgtggtga tgagtctgaa ttaagtatcc gtcaattaat tagaattgaa aatggagaat
    29341 ccagaccaac actaacaaag ttaaaatata ttgctgaacg tttggaggtt gaagattaca
    29401 agttgatgcc aagttatata gagttggata aggaatacct agaattgaag tatttcttga
    29461 tgaggactcc tacatacgaa gatgaaacta tcgcccaaaa gaaagagagt gtttttgata
    29521 agatttttga agagtattat gataggctac ctgaggaaga aagatttatc atcccaaatt
    29581 attcatatct agcactagcg aactacacag ttcaaaaatt accagaaaag ctagttgaaa
    29641 tactgtcctt ctggtgattt tgcttaattt ctgatgttcg agacatgatt gaggagattt
    29701 gtcttgattt tttcctaaaa aagggcagac tcctcccttg gtttgatgct cgatttttaa
    29761 aataaggtga cttattctgt taggcagttt tcccctgccc tctagctcta tatggaacag
    29821 ggagtatcag atttatctgg cagattgtat caaataaggc ttgaaactgt tttgaatagg
    29881 cgtatagact tgagaatttg agaatatgtc gtctagcagt agagacatat tttccggcaa
    29941 tatgaaggaa gagacgtcga aaacgcttga tagtcaaggc ctttacttca tcaccagcta
    30001 gctgctttaa aaagaggtag agattataag ccagacagcc catcatcata cgtacttcat
    30061 tcttaatcat ggtcgaacta tctgtcttat ccccaaagaa tcctgctttc ctttctttga
    30121 taaagttttc agcattccct cgttcacgat agaattgaaa cagctcctca ctatctacac
    30181 tgcttaaatt ggtcaaatga acttttttac aaccataaaa aagagcactt aatcgtactc
    30241 ttctctttta aggattagtt gaattaattc aaatccacta gttctcctgt ttctaggtag
    30301 actaggcgtt cacaaatgtt agcaatgtaa tcagcgaagc gttccagatg ccctatgata
    30361 taaaggtatt gagttccatt gggaattgag gtttcttggt ctttcataag tccaatgatt
    30421 tcctttgata aggcataata atattggtca atctgttcat ctttttgagc aatactaata
    30481 gcttttgagg cttggtgcaa aggaaaggca accaataaat cggctagcat gctgagggat
    30541 aatttaccca tttggtgtaa ctgttcttcg tcaggggcta gttgattttc ttttagttgc
    30601 aaaacagctt tggcaatgcc tgccatatgg tctcccatac gttcaaggtc tgaacaagaa
    30661 gacatgatgc taatcacaaa tcgaaggtca gacacttgtg gctgctgcaa ggccaacaaa
    30721 cgggcacagg tcaattcgat agcgctttga ccttggttta tagcatgatc cttattgata
    30781 attagctctg ccatctcctt gtctttggag gctaaggcca gtaaggcttt tgaagctgtt
    30841 tcaaggacaa gttgccctag tcctaaaaag gattgttcta attcatgcaa ttctaagtca
    30901 aattgatttc tcataggttt ttccttcctt atccgaaccg tcctgaaata tagtcttctg
    30961 tgcgctgatc ttttggattg gtaaacacgt caacggtatc tccaaattcg caaatttctc
    31021 ctgttaagaa aaaagcagtt ttatctgaaa tacgtgaagc ttgttgcatg ttatgggtaa
    31081 caatgataat cgtataatcc ttttttagtt gctgaatgag gtcttcaatt tttaaagtgg
    31141 agatagggtc taaggctgaa gtcggctcat ccattaacag aatatcaggt tctactgcta
    31201 aagctcgcgc aatgcaaagg cgttgctgct gaccgccaga taaggacatg gcactctttt
    31261 taagatcatc tttgacttct tcccaaatgg ctgccccttt taaagatttc tccactaagg
    31321 catctaattg ttttttgtct cgaataccat gtgtccttgg gccataagcc acgttatcat
    31381 agatagacat ggcaaaggga ttaggctgtt gaaaaaccat ccctacacgc ttacgtagct
    31441 gattaaggtt gaatttgcta ctataaatat cttgctcatc taagaggact tggccttcaa
    31501 tatggcaaga aggaaccaaa tcgttcatcc ggttaagggt ttttagaaaa gttgatttgc
    31561 cacaaccaga tgggcctatc aaggcagtaa tctgtctttc tggtaattga atcgaaatat
    31621 tttttaaggc ttgaaaatcc ccgtaaaata agtctaggtg tctgactgaa aatgttccca
    31681 tactaggaag ctcctttcac aagttttcga gataataagc ttgatagagt atttatcatt
    31741 aaaacagtaa taatcaaaat cacaccggta gcataggctt cattgacatg tagcccctca
    31801 cttgacagca tatacatatg cagggctaga gaacgacctg aagacatgag actacttggc
    31861 gtattggtag aggtacctaa tgtatacatg agggcagctg tctcaccaac gatacggcca
    31921 atagctagta tcactccagc taaaatacct ggcatggcaa ctggtagaac aattctaaaa
    31981 acagtccgta acttacctgc cccaagtcca taacttgctt gacgcatgct atcactaaca
    32041 gataaaaggg cttcttctgt tgagcgaata atgactggca acaccatgat gactgaggtt
    32101 aagattcctg ataacagaga gtattgaaaa cctaagaaga ctacaaagaa gagcatgcca
    32161 aacagaccaa aaacaatgga aggaatccca gacaaggtat ctgaggccaa tcgcatgatt
    32221 ttaacacaaa gggaatcttt ttttgtatat tccacaagat aaaaaccagc aaaaatccct
    32281 atgggcaagg ctaaaagaag agcaccaaag accagaataa cggtggaaat aatcgctggc
    32341 ataagggaaa tgttctcaga agtataagtc caagaaaaga gggatagact tagatgaggt
    32401 aaacctttga tgaggataaa accaatgatt aaaaagagag agccaaaggt taaagctgaa
    32461 aaacaataaa cgagaagttt tagcaggtat ttactcataa gatgattttc ctttcaagta
    32521 ggcaaagtag gcattaatca agagaataag gaaaaagaga actgctgagg ttgcaataag
    32581 ggcttcccta tgctgacctg atgcgtaagc catttccaga acaatattgg ttgttaaggt
    32641 tctggttcct gaaaagagtc cacttggaat aatcggctgg ttgcctgcca ccaaaataac
    32701 tgccatggtt tcacctactg cgcgaccgat gcctaaaata actgctgata aaataccaga
    32761 tctcgcagct ggcaagatga cactaaaaat actccgttca tgactagctc ctagagccaa
    32821 gctaccagaa taatacgttt tgggaactgt tcggatagca gattctgaca aactgataat
    32881 ggttggcaaa atcattattc ctaatagtaa cgaagcggtt aggacactca tgccatttcc
    32941 taaaaagctt ctaatccaag gcaccaataa ttgtaggccg aaaaaaccat aaacaataga
    33001 tggaatggcc gccatcaagt tgatagctga ttttaagaag ccatagacgg gctttggaca
    33061 ataataaacc ataaacaccg atgtcaagat gcctgttggc accccaatca caatcgctcc
    33121 taaggtaatt aataaggaac caacgatcat tggtaaaata ccatagcttg ccggaatgtt
    33181 cgttggcgac caatcactgc ctaataaaaa acgggcaaag ccgtagttag ccatgaaagg
    33241 taagccatta ctaaaaataa agaaacagat tagcaaaata gctacaacag ctactgttgc
    33301 actcatgaaa aaaattgccc taaaaactgc ttctttgaag gcttgtttta tcacatcttg
    33361 tcctttctag tgaagaaagt aagggagata cgacacctcc ctacttgcct tctttatctt
    33421 attgtacgat gaaacgtctg catctcttta gagatttatg gagcaaacat tttatttaat
    33481 cttgtcccag gtggttaatt tgccactaaa aacgtctgca agttcagcca tactgacttg
    33541 gcttgcctta ttgtcattat tgaccacaac agcaataccg tctaaagcaa tagcatcatg
    33601 ggtgagactc ttaccttctt caggagttaa ttccctagaa accataccaa tatcagcggt
    33661 tttctcctta acagcggtaa tacctgctga agacccatta gaggtaatat caatcgtaac
    33721 ttctggattt tcttttttat aagcttctgc taatttttcc attaaagaag atactgaagt
    33781 ggaacctaca acagacaact tgcctgataa gtgttggctt gtatattctg tggtttcagt
    33841 tttagcttca ataaatttat tatctgtgac cacttgttga ccttgtttgg agtggataaa
    33901 gctgataaaa tcttgaccta gcttggaaag attagaagac caaacaatgt tgaagggacg
    33961 ttgaagaggg tattcaccat ctaaaactgt gtctcgacta gccttgacac catcaatctc
    34021 taaagccttg acagatttcg ttaaagatcc caaggagatg tagccgatag cattagcatt
    34081 cccttgaact gctgagagaa caccttctgt actattttga atcacagctg ttttggcagt
    34141 gttgtcaatt tttttatcac cgtctttttt gagaatccct gtgatttctg tgaaggcacc
    34201 ccgtgttcca gagccatttt ctcgtgaaat cacctcaatc gttcctgaag ctgactgttt
    34261 ggaagcagct gactgattgc cacaggcaac aagcccaaat cctgataagc caatggctgc
    34321 aagagtaagc atttttttga atttcataat aatcaccttt atctctatgt atttttcttg
    34381 tgtaggctta ctacatttat agtctaacaa gtctttgtaa aggtttatcc ctgattcatg
    34441 taaagattgt gtaaagaatc aaaaaaagcc acttttgaaa aatggctgct cctaaaaata
    34501 gctttaaaaa ttattagtcc tgtgcgaaag attggttagg aagaaaaatc gtgaagcaac
    34561 tgcctctgcc aagctgactc gtcaccgtga cttggccacc taataattga ctgagttctt
    34621 tgacaatggc aaggccaaga ccagtgccac cagtttgtct gcttcgacct ttattaactc
    34681 ggtaaaaacg ttcaaaaata cgatcctgct ctaattgact aataccaatc cctgtatctg
    34741 atacagaaat cttaatgcct tcgttcacct tttgggtctt gacctcaatt tttccccctt
    34801 gttcagtgta acggatggca ttggataaaa gattgagtaa gatttgggaa agtaattgac
    34861 tatctgatac gagggtgaca tcatctggca cctgcacctt tagctgtaaa tccttcttct
    34921 tgagctgagg ttgcaagctt tgagtcaaat cctgtacaaa ttcagccaaa gaaagggtcg
    34981 tccattgtat aggcatttgt tgagccttag ataaggtaag aagatgctca acaatatgct
    35041 caagacgcaa actttctttg taaataatgt ctagaaagtc atccttgagc gcttcttctt
    35101 cagctgacat ccccttaatg gtttcagcaa agcccttaat tgaagtaact ggtgtcctca
    35161 attcatggga ggcatttgag acaaaggcta aatttaactt ttcataagtt ctaatcgttg
    35221 ttaaatcata tagcaagacg agcacagctt ccacagattg ggtggggcta aaaacgggaa
    35281 ctgctgtcac ttctaaaatc aagtcaccct catgaaaccc acttacttct tgttttaacc
    35341 ttgttttttg atcaaaggct tggtgaacta aattccgaat atccatccgt ttgaggtcat
    35401 caagtgaact tatgtcgccg tccacatcgg gaaaataatg aggcagagag cgactggata
    35461 ataacatctg accttgagcg gaaactaaaa acgtccccat ggttaggtgc gacagaagaa
    35521 cctccattgt ttcggctagg tccttgtatt gctgatcctg ttgggagact ttggttttta
    35581 ggccagacac atactgagcc aaagacttta agtcttcttg ccctttttct aaaaagtatt
    35641 cactactggt caagagaggt tggtgcaagg tctcaaaagc aacttcccat ttccaaaggc
    35701 aaaagagcca gtagccacct tgtcccaaag aaagggctag aagaaagaga ccgatgcctt
    35761 tactgatcca agttaatgcc atccctgcaa tcagaatgag gctaacactt agattgacta
    35821 gccaaaattg aaggtagcgt ttcatctata actccttgaa cttataacca taaccccgaa
    35881 tggttcgaat aaattgaggg gctttaggat tgtcttcaat tttttccctc aacttaccaa
    35941 tatgaacgtc caccaaacgt gtttcctgcc caaagtcata cccccagata cgttccaaaa
    36001 gacgctctct agtcagtgtc atgttgggat gtttcataag atagagcaag agttcaaatt
    36061 cttttggggt caaactcagt aacttattcg ccttgtagac ttcatgacgc tcagggtata
    36121 ctttcaaggt cccaaatagc caagaatcgt cagcgatatt atctgaatca tctccttctt
    36181 gttctccttt agttcgcctg aggacagcct tgacacgcgc cagcaattct ctagggctaa
    36241 aaggcttggt caggtagtca tcagccccta attccaaggc caaaacctta tcaaattcat
    36301 cacttttcgc agaaaccatc ataattggag ttttgacgcc tttggctctc agccgcttac
    36361 aaacttccat gccatctaat tgtggtaaca tgatatcaag caagataaaa tcaaagggtt
    36421 ctgtttctgc caaagctaag gccttccgtc catttgttac caattgagta gaaaagcctt
    36481 ccttacttaa atggtagtca agcaatttca gaatgtgttc ttcatcatcc actaataaga
    36541 cttgttttgt catctattat ctcctattgg taacattata acacaattat cagaaatcct
    36601 aacattgcta aatcagatta aatttgctta tcaagactag tatctggtca aacgctcaat
    36661 catctccttg tgctctggat aggtcgccag tagatctacc ctttcaaata attcaaaatc
    36721 ctcaaattca aaaccaggag caacaagaca agaaaccaga gcataatcct tatcaactgt
    36781 tgatccccaa atagtgccct taggaacaca gtagtgaagt tgttgccctt tggatatgtc
    36841 caggcctaaa gtgactgctt cgtagtgacc atctgctgta atcatgtgaa cagtaagtgg
    36901 ggatcctgca tgaaaatacc agatttcatc tgctgtcaat cggtgaaaat gtgaaggatt
    36961 cgtttcttct aataagaaat aaatactggt ataaagcgcc cttcccttac cagcaaggtt
    37021 tatagtgtct gaagcttttt ttgtttgtct aaaatagcca ccttcaacat ggggagctaa
    37081 ctctagagtt cttatcaagt cttctttatc catcggggcc aatgggttga agtaactctt
    37141 gttcaaagtg gttttacgat ttcaagaact cctctcagtt ctgaggacac ggtaatgatt
    37201 gatgcgacgg aagtacaaat caatcgccct aaaaaaagaa ttagcgaatg attctggtaa
    37261 aaagaaattt cacgctatga aggctcaagc gattgtcaca agtcaaggga gaattgtttc
    37321 tattgccatg atatgaagtt gttcaaaatg agttgcagaa atatcggaca agctggtaaa
    37381 atcttggctg acagtgatta tcaagggctc atgaagatat atcctcaagc acaaactcca
    37441 cgtaaatcca gcaaactcaa gccgctaaca gctgaagata aagcctataa ccatgcgcta
    37501 tctaaggaaa gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt taaaatattt
    37561 tcaacaacct atcgaaatca tcgtaaacgc ttcggattac gaatgaattt gattgctggt
    37621 attatcaatc atgaactagg attctagttt tgcaggaagt ctattatttg gttaggtgaa
    37681 ttagtgaagt gtttaggcaa gtgtctctgg ttacgacgtc atggcctcta aatcgattat
    37741 atttaggggt catgactagt gaagcagtta gctagttcgc atataagcgg ctagcgtcta
    37801 acaattagga actttagttc caataacttt aagattacga cgttttagga cataaatcga
    37861 tcatatttat gtcctaaaac tagtgaagcg cctagccaaa gtccgaatag gatttggcgt
    37921 tagttactta gattgctttg caatcaagta actttggcga tttacatctt ctctggcgct
    37981 tctactccaa gcaagcgaag ggcttctttg agaacgactg cggttgcgta gctgagggct
    38041 agacggctgt cgcgttctgg gctttcatcc aagatacgtg tatgtgcata gtatttgtta
    38101 aaggattgag ccaggctaat tgcaaattta gcaatgatag aaggttcaaa gttatctgcc
    38161 gcacggttga taatacgtgg gaagtcttga atgagtttaa tgatttccca gctttcagta
    38221 tcattcaagc tatagttgcc agctgtttct ggtttgaaat cggctttgcg taagatagat
    38281 tggatacgag cgtaggcata ttgaacgtaa ggtccagttt caccctcgaa ggataccata
    38341 gcttctaggt cgaagtcgta tccatttgta cggtcagttt tgaggtcata gaatttaatg
    38401 gctccaaccc caacagcatg tgctacttgg tctttgtttt ctagttcagg atttttagcc
    38461 tcgatttgga ccttggcacg gctaacagcc tctgcaacag taggctctag caagatgaca
    38521 ttccctttac gagtagagag cttcttccct tcttttgtaa ccagaccaaa aggaacgtgg
    38581 gtaatgtcgt cactccaatc gtagcccatc tcttgcaaga cagctttgag ttgtttaaag
    38641 tgggcagatt gctcttgacc aacgacgtag atagatttag caaattggta ttcattttta
    38701 cggtagaggg ctgcagccaa gtcacgtgtg atatagagag ttgcaccatc agacttcttg
    38761 atgagggctg gatgttcaat tccatatttc tcaagattca caacttgggc accttctgat
    38821 tcaagaagta gtcctttttc agaaagaatg tctacaactg catccatctt atcattgtag
    38881 aaggcttctc cgttatagct gtcaaattca accttcaatt cattgtaaag gcggttaaat
    38941 tccactaaac tttcatcgcg gaaccattgc caaagagcga gagcttcctc atctccattt
    39001 tcaagtttac ggaaccattc gcgcgcttct tcatccaagc tagggtcatt ttcagcttca
    39061 gcgttgatgc ggacatagag tttaaggagt tcatcgattg gatgagcttt tacagcttct
    39121 tcgtcgcccc attttttgta ggcaacaatc aacatcccaa attgtttacc ccagtctccc
    39181 aaatggttga ccttgaccgt ttgataaccg attttttgga aaatatgtga caagctatct
    39241 ccgataacag ttgaacgcag gtggccaata gaaaatggtt tagcgatatt cggactagac
    39301 atgtcgataa caacattttc ttgtttgcca atattttggt cagcatagtg ttctttttca
    39361 gtggtaacag cttgcaatac ttgagcagaa atggcagatt tatcaaggaa aaagttaacg
    39421 taaggtcctg ttgcgacaac tttttcaaag gcttggctgt tcattttttc agccagttca
    39481 gccgcaatca tttgtggtgc tttacgttcg actttggcaa gagaaaaagc agggaaagca
    39541 atgtctccca tttctgagtt tttaggggtt tccagtaact ttaaaatagc ctcttggtcc
    39601 aggctatcaa tgatgctaga taattcgcta gcaatcaatt cttttgtatt cattaagagc
    39661 tcctttttgg acttttctac tattttatca caattttaaa gaaagaagaa aaaatttttg
    39721 aaatctcctg tttttttggt ataatatggt tataaatata gttataaata tgcacgcaag
    39781 aggattttat gagaaaaaga gatcgtcatc agttaataaa aaaaatgatt actgaggaga
    39841 aattaagtac acaaaaagaa attcaagatc ggttggaggc gcacaatgtt tgtgtgacgc
    39901 agacaacctt gtctcgtgat ttgcgcgaaa tcggcttgac caaggtcaag aaaaatgata
    39961 tggtgtatta tgtactagta aatgagacag aaaagattga tttggtggaa tttttgtctc
    40021 atcatttaga aggtgttgca agagcagagt ttaccttggt gcttcatacc aaattgggag
    40081 aagcctctgt tttggcaaat attgtagatg taaacaagga tgaatggatt ttaggaacag
    40141 ttgctggtgc caatacctta ttggttattt gtcgagatca gcacgttgcc aaactcatgg
    40201 aagatcgttt gctagatttg atgaaagata agtaaggtct tgggagttgc tctcaagact
    40261 tatttttgaa aaggagagac agaaaatggc gatagaaaag ctatcacccg gcatgcaaca
    40321 gtatgtggat attaaaaagc aatatccaga tgcttttttg ctctttcgga tgggtgattt
    40381 ttatgaatta ttttatgagg atgcggtcaa tgctgcgcag attctggaaa tttccttaac
    40441 gagtcgcaac aagaatgccg acaatccgat ccctatggcg ggtgttccct atcattctgc
    40501 ccaacagtat atcgatgtct tgattgagca gggttataag gtggctatcg cagagcagat
    40561 ggaagatcct aaacaagcag ttggggttgt taaacgagag gttgttcagg tcattacgcc
    40621 agggacagtg gtcgatagca gtaagccgga cagtcagaat aattttttgg tttccataga
    40681 ccgcgaaggc aatcaatttg gcctagctta tatggatttg gtgacgggtg acttttatgt
    40741 gacaggtctt ttggatttca cgctggtttg tggggaaatc cgtaacctca aggctcgaga
    40801 agtggtgttg ggttatgact tgtctgagga agaagaacaa atcctcagcc gccagatgaa
    40861 tctggtactc tcttatgaaa aagaaagctt tgaagacctt catttattgg atttgcgatt
    40921 ggcaacggtg gagcaaacgg catctagtaa gctgctccag tatgttcatc ggactcagat
    40981 gagggaattg aaccacctca aacctgttat ccgctacgaa attaaggatt tcttgcagat
    41041 ggattatgcg accaaggcta gtctggattt ggttgagaat gctcgctcag gtaagaaaca
    41101 aggcagtctt ttctggcttt tggatgaaac caaaacggct atggggatgc gtctcttgcg
    41161 ttcttggatt catcgcccct tgattgataa ggaacgaatc gtccaacgtc aagaagtagt
    41221 gcaggtcttt ctcgaccatt tctttgagcg tagtgacttg acagacagtc tcaagggtgt
    41281 ttatgacatt gagcgcttgg ctagtcgtgt ttcttttggt aaaaccaatc caaaggatct
    41341 cttgcagttg gcgactacct tgtctagtgt gccacggatt cgtgcgattt tagaagggat
    41401 ggagcaacct actctagcct atctcatcgc acaactggat gcaatccctg agttggagag
    41461 tttgattagc gcagcgattg ctcctgaagc tcctcatgtg attacagatg ggggaattat
    41521 ccggactgga tttgatgaga ctttagacaa gtatcgttgc gttctcagag aagggactag
    41581 ctggattgct gagattgagg ctaaggagcg agaaaactct ggtatcagca cgctcaagat
    41641 tgactacaat aaaaaggatg gctactattt tcatgtgacc aattcgcaac tgggaaatgt
    41701 gccagcccac tttttccgca aggcgacgct gaaaaactca gaacgctttg gaaccgaaga
    41761 attagcccgt atcgagggag atatgcttga ggcgcgtgag aagtcagcca acctcgaata
    41821 cgaaatattt atgcgcattc gtgaagaggt cggcaagtac atccagcgtt tacaagctct
    41881 agcccaagga attgcgacgg ttgatgtctt acagagtctg gcggttgtgg ctgaaaccca
    41941 gcatttgatt cgacctgagt ttggtgacga ttcacaaatt gatatccgga aagggcgcca
    42001 tgctgtcgtt gaaaaggtta tgggggctca gacctatatt ccaaatacga ttcagatggc
    42061 agaagatacc agtattcaac tggttacagg gccaaacatg agtgggaagt ctacctatat
    42121 gcgtcagtta gccatgacgg cggttatggc ccagctgggt tcctatgttc ctgctgaaag
    42181 cgcccattta ccgatttttg atgcgatttt tacccgtatc ggagcagcag atgacttggt
    42241 ttcgggtcag tcaaccttta tggtggagat gatggaggcc aataatgcca tttcgcatgc
    42301 gaccaagaac tctctcattc tctttgatga attgggacgt ggaactgcaa cttatgacgg
    42361 gatggctctt gctcagtcca tcatcgaata tatccatgag cacatcggag ctaagaccct
    42421 ctttgcgacc cactaccatg agttgactag tctggagtct agtttacaac acttggtcaa
    42481 tgtccacgtg gcaactttgg agcaggatgg gcaggtcacc ttccttcaca agattgaacc
    42541 gggaccagct gataaatcct acggtatcca tgttgccaag attgctggct tgccagcaga
    42601 ccttttagca agggcggata agattttgac tcagctagag aatcaaggaa cagagagtcc
    42661 tcctcccatg agacaaacta gtgctgtcac tgaacagatt tcactctttg atagggcaga
    42721 agagcatcct atcctagcag aattagctaa actggatgtg tataatatga cacctatgca
    42781 ggttatgaat gtcttagtag agttaaaaca gaaactataa aaccaagact cactagttaa
    42841 tctagctgta tcaaggagac ttctttgaca attctccact tttttgctag aataacatca
    42901 cacaaacaga atgaaaagga gctgacgcat tgtcgctccc ttttgtctat tttttaagga
    42961 gaaagtatgc tgattcagaa aataaaaacc tacaagtggc aggccctggc ttcgctcctg
    43021 atgacaggct tgatggttgc tagttcactt ctgcaaccgc gttatctgca ggaagtctta
    43081 ggcgccctcc ttgctgggaa atatgaagct atttatagta tcggggcttg gttgattggt
    43141 gtggccgtag tcggtctagt tgctggtgga ctcaatgttg tcctcgcagc ctatattgcc
    43201 caaggagttt catccgacct tcgggaggat gccttccgta aaattcaaac cttttcttat
    43261 gctgatattg aacaatttaa tgcgggaaat ctagtcgttc gaatgacaaa tgatatcaac
    43321 cagattcaga acgttgtcat gatgaccttc cagattcttt tcagacttcc cctcttgttc
    43381 atcggttcgt ttatcctagc ggttcaaacc ttaccttctc tgtggtgggt gattgttctc
    43441 atggtagtct tgatttttgg tttgactgct gtcatgatgg gaatgatggg gcctcgtttt
    43501 gccaagtttc aaacccttct tgagcgcatc aatgccattg ccaaggaaaa tttacgtggc
    43561 gttcgtgtgg tcaagtcctt tgtccaagaa aaagagcaat ttgctaagtt tacagaggtc
    43621 tcagacgagc ttcttggtca aaacctttac attggttatg ccttttcagt agtggaaccc
    43681 tttatgatgt tggttggtta cggggcggtc ttcctctcta tttggctggt cgcgggaatg
    43741 gttcagtcgg atccgtctgt tgttggttcc atcgcttctt ttgttaatta cctaagccag
    43801 attatcttta ccattgttat ggttggattt ttgggaaatt ctgtcagccg tgccatgatt
    43861 tccatgcgtc gtattcgaga aattcttgac gcagagccag ctatgacctt caaggatatc
    43921 ccagatgaag agttggttgg aagccttagc tttgaaaatg tgacctttac ctatccaatg
    43981 gacaaggaac cgatgctgaa agatgtgagc tttactattg aacctggtca aatggttggt
    44041 gtagttggag cgactggtgc aggaaagtca accttggctc aattgattcc acgtctcttt
    44101 gatccacagg aaggggctat caaaatcgga ggtaaggata ttcgagaagt gagtgaagga
    44161 accctgcgta aaacagtttc catcgttctc caacgtgcca ttctttttag tggaacgatt
    44221 gcagataact tgagacaggg gaagggaaat gctactctat ttgaaatgga gcgcgcagcc
    44281 aatattgccc aggctagtga attcattcat cgtatggaga aaacctttga aagtccagtt
    44341 gaagaacggg gaaccaattt ctctggtgga caaaaacaaa ggatgtcgat tgcgcgtggg
    44401 attgtcagca atccacgtat tctgattttt gatgattcga cctcagcctt ggatgccaaa
    44461 tcagagcgct tggtgcaaga agctttgaat aaggacttga aggggacgac aaccattatt
    44521 attgctcaaa aaattagctc ggttgtccat gcagacaaga tcttggttct aaatcaagga
    44581 cgattgattg gtcaaggcac gcatgcagac ttggttgcca acaatgccgt ttaccgtgaa
    44641 atctatgaaa cacagaaatg aaagacaaac tataagaaaa gtcaatagtt ttatctaaac
    44701 tatttcttat ttcaatttga tgatttggcg atgattttag agcacggcaa aaagctattg
    44761 aaaaagtcca ttttttcaaa ggtaatcctg tgttaatttc agaaattaca tcactttttg
    44821 ttcgtcaaat ggcagctctt ttttaggata taaaacaggg ttcggataag tttttttgca
    44881 aggtggatga tggctacatt gtaatgtttt ccttgttcta acttagtctt aagataggcc
    44941 ttaaaagcag gtgaaaagcg agggcatgct ttggcagctt gtatgagtac ctaccgcaga
    45001 tgaggggaac cccgtttgac cattctttct gctaaatcaa tctgacctga ctgataaata
    45061 gaagaatcca gtccagcgaa agcttgtaat tgagcaggat tatcaaaggc atgaatattt
    45121 cgaatctcgg ctaaaatgac cgcccctaaa cgacccccaa tcccagtaac cgtcgtgatg
    45181 accgagttga actcagccat caagtcattg acacattttt tcgccttgtc aatgagcctc
    45241 ttgtaatgtt tgatgttttc attacaagag ataaaacgtt tatgcgttat caaactcatt
    45301 accaattgaa acaaaaagct gtggttagat cctttcggaa attgtcaagc gattggagga
    45361 aatgaactaa tccacagcgg cttattccaa gtataccact tgggctttgg cagtagctaa
    45421 ctgcgctaaa tataatataa ggaggagtaa aatgaagaca gttcaatttt tttggcatta
    45481 ttttaaggtc tacaagttct catttgtagt tgtcatcctg atgattgttc tggcgacttt
    45541 tgcccaagcc ctctttccag tcttttctgg acaagcggtg acgcagctag ccaatttagt
    45601 tcaagcttat caaaatggca atccagaact tgtatggcaa agcctatcag gaatcatggt
    45661 caatcttggc ctgctggttt tggttctatt tatctctagt gtaatataca tgtgtctcat
    45721 gacgcgcgtg attgcagaat cgaccaacga gatgcgcaaa ggcctctttg gtaagcttgc
    45781 tcagttgacg gtttctttct ttgaccgtcg acaagatggc gatatcctgt ctcattttac
    45841 cagtgatttg gataatatcc tccaagcctt taacgaaagc ttgattcagg tcatgagcaa
    45901 tattgtttta tacattggtc tgattcttgt catgttttcg agaaatgtga cgctggctct
    45961 catcaccatt gccagcactc cattggcttt ccttatgctg attttcatcg tgaaaatggc
    46021 acgtaaatac accaacctcc agcagaaaga ggtagggaag ctcaacgcct atatggatga
    46081 gagcatctca ggccaaaaag ccgtgattgt gcaaggaatt caagaggata tgatggcagg
    46141 atttcttgaa caaaatgagc gcgtgcgcaa ggcaaccttt aaaggaagaa tgttctcagg
    46201 aattcttttc cctgtcatga atgggatgag cctgattaat acagccatcg tcatctttgc
    46261 tggttcggct gtacttttga atgataagtc tattgaaaca agtacagccc taggtttgat
    46321 tgttatgttt gcacaatttt cacagcagta ctaccagcct attatccaag ttgcagcgag
    46381 ttggggaagc cttcagttgg cctttactgg agctgaacga attcaggaaa tgtttgatgc
    46441 agaggaggaa atccgacctg aaaaggctcc aaccttcact aagttgcaag aaagtgttga
    46501 aatcagtcat atcgattttt catacttgcc tgataaacct attttgaaag atgtcagcat
    46561 ttctgcccct aaaggccaga tgacagcagt tgttgggcct acaggttcag gaaaaacgac
    46621 tattatgaac ctcatcaatc gcttttatga tgttgatgct ggtggtattt attttgatgg
    46681 taaagacatt cgtggctatg acttagatag tcttagaagc aaggtgggaa ttgtattgca
    46741 agattcggtc ttgtttagcg gaacgattcg agacaatatc cgatttggtg tgccagatgc
    46801 taatcaggaa atggttgagg tagcagcaaa agcaacccac attcacgact atatcgaaag
    46861 tttgcctgat aagtacgata ctcttattga tgatgaccag agcatctttt caacagggca
    46921 gaagcaattg atttcaatcg ctcgaaccct gatgacagat ccagaagttc tcattctcga
    46981 tgaagcaact tcaaacgtag atacggtgac ggaaagcaag attcagcatg ccatggaggt
    47041 ggttgtagca ggtagaacta gtttcgtcat tgcccaccgc ttgaaaacca ttctcaatgc
    47101 agatcagatt attgtcctta aagatggaga agtcattgaa cgtggtaacc accatgaact
    47161 tttgaagcta ggtggctttt attcagaact ctatcacaat caatttgttt tcgaataaga
    47221 aagaagttgt cctatgtggg cagctttttc ttgtccataa aaaatgttta tcacagcctt
    47281 aaaaaaaaca tattagacga aagtcatttt gagtgatatg ataggactat cgttagtatt
    47341 cgaaaggaga ggcatcatgg ctagaacggt tgtaggagtt gctgcaaatc tatgtcccgt
    47401 agacgcagaa ggcaaaatca ttcattcatc tgtatcttgt agattcgcag agatcattcg
    47461 tcaagtcggt ggtctccctt tagtcattcc tgttggtgat gagtcagttg tacgtgatta
    47521 tgtggaaatg attgacaaac tcattttgac aggaggccaa aatgttcatc ctcagtttta
    47581 tggagagaaa aagaccgtcg aaagcgatga ttacaatctg gtccgtgacg aatttgaatt
    47641 ggcactcttg aaggaagcgc ttcgtcagaa taaaccaatt atggcaatct gtcgcggtgt
    47701 ccaacttgtc aatgttgcct ttggtggaac cctcaatcaa gaaatcgaag gtcactggca
    47761 aggactacct ttcgggacat ctcactctat tgaaacagta gaaggaagcg tggtggctaa
    47821 gctatttggg aaagaaagtc aggtcaactc agtccatcgt caaagcatta aagatttggc
    47881 acctaatttc cgtgtaactg ctattgattc aagagaccaa actattgaag cgattgagtc
    47941 tatcgacgag caccgcatta tcggtttaca gtggcatcca gagtttctgg ttaatgaaga
    48001 agatggcaat ttagaattat ttgagtattt attgaatgaa ctgtaacgat tggaacatct
    48061 ggtcgttctt tcttttattt tttcaaaatt tttagaatgt ggcattttac gcaaacgttt
    48121 gaattctgat aaaaattgga gaaattcgac aaaaaaactt gaaaaaaacg aaggtaagcg
    48181 ttatgataga aaagaagaaa tattggagga agaacatgtc acatattaaa tttgattatt
    48241 caaaagtttt agacaaattt gttgcaccac atgaagtgga atacatgcaa tcacaagtaa
    48301 cagcagcaga tgaattgatc cgtaaaggaa ctggtgctgg tagcgacttc ttgggatggt
    48361 tggaccttcc tgaaaaatac gaccgcgaag aatttgaccg catcttgaaa gctgctgagc
    48421 aaatcaagtc agacagcgat gttttggttg tgatcggtat tggtggatct taccttggtg
    48481 caaaagcagc aatcgacttc ttgaatcacc attttgctaa cttgcaaaca aaagaagaac
    48541 gcaaagctcc acaaatcctt tacgcaggaa actcaatctc atctacttac cttgctgact
    48601 tggtagagta tgttgcagac aaagacttct cagtaaacgt aatttctaaa tcaggtacaa
    48661 caactgaacc agcgattgct ttccgtgtct ttaaagaact cttggttaag aaatacggtc
    48721 aagaagaagc taacaaacgt atctatgcaa caactgaccg ccaaaagggt gctgttaagg
    48781 ttgaagcaga cgctaacggt tggggaacat ttgttgttcc agatgatatc ggtggacgct
    48841 tctcagtatt gacagccgtt ggtttgcttc caatcgcagc atcaggagct gacatcaaag
    48901 ctcttatgga aggtgcgaat gcagctcgca aagactacac ttcagacaaa atctctgaaa
    48961 acgaagctta ccaatacgca gtcgttcgta acatccttta tcgtaaaggc tatgcaactg
    49021 agatcttggt aaactatgag ccatcacttc aatacttctc agaatggtgg aaacaattgg
    49081 ctggtgaatc agaaggaaaa gaccaaaaag gtatctaccc aacttcagcc aacttctcaa
    49141 ctgacttgca ctcacttggt caatttatcc aagaaggaac tcgtatcatg tttgaaacag
    49201 ttgtccgtgt tgacaaacct cgtaaaaacg tgcttattcc tactttggaa gaagaccttg
    49261 acggacttgg ttaccttcaa ggaaaagacg ttgactttgt aaacaaaaaa gcaactgacg
    49321 gtgttcttct tgcccacaca gatggtgatg taccaaacat gtatgtgact cttccagagc
    49381 aagacgcttt cactcttggt tacactatct acttcttcga attggcaatt gccctttcag
    49441 gttacttgaa tgctatcaac ccatttgacc aaccaggtgt tgaagcttat aaacgtaaca
    49501 tgtttgccct tcttggaaaa ccaggatttg aagaattgag caaagaactt aacgcacgtc
    49561 tataatagaa gaaaagagtg gtttgcccac tctttttact ctctttatcc atagaaattg
    49621 gactcagcca agacttgtga tataatatag aaagcaaaaa ggcagacgcc tagataatag
    49681 gagaaactat gtcaaaagat atccgcgtac gttacgcacc aagtccaaca ggactactac
    49741 acatcggaaa tgcccgtaca gcattgttta actacttgta tgcgcgccat catggtggaa
    49801 catttctcat ccgtatcgaa gatactgacc gtaaacgcca tgtcgaggat ggtgaacgtt
    49861 cacaacttga aaaccttcgc tggttaggca tggattggga tgaaagtcca gaatcacatg
    49921 agaattatcg ccagtctgag cgtttggact tgtatcaaaa atacattgac caactattag
    49981 ctgaaggaaa agcctataaa tcttacgtta cagaagaaga gttggcagct gaacgtgaac
    50041 gtcaagaagt agctggcgaa acaccacgct acatcaatga ataccttggt atgagtgaag
    50101 aagaaaaagc ggcttatatc gcagaacgtg aagcagctgg tatcatacca acagttcgtt
    50161 tggctgtcaa tgagtcaggt atctacaagt ggcatgatat ggtcaaaggt gatatcgaat
    50221 ttgaaggtgg caatatcggc ggtgactggg ttatccaaaa gaaagacggt tacccaactt
    50281 acaactttgc cgttgttatc gatgaccacg atatgcaaat ctctcatgtt atccgtggag
    50341 atgaccatat tgctaataca ccaaaacagc ttatggtcta tgaagctctt ggttgggaag
    50401 ctccagagtt tggtcacatg accttgatta tcaactctga gactggtaag aagttatcta
    50461 aacgtgatac taatacactt caatttatcg aagattaccg aaagaaaggt taccttccag
    50521 aagcagtctt taactttatt gctcttcttg gttggaaccc aggtggtgaa gatgagattt
    50581 tctctcgtga agaactcatt aaactttttg atgaaaaccg cctcagcaag tcaccagcag
    50641 cctttgatca gaaaaaatta gactggatga gcaatgatta tatcaagaat gcagaccttg
    50701 aaaccatctt tgaaatggca aaaccattct tagaggaagc aggccgtttg actgacaagg
    50761 ctgaaaaatt agttgagctc tataaaccac aaatgaaatc agtagatgag attatcccat
    50821 tgacagatct tttcttctca gatttcccag aattgacaga agcagagcgc gaagtcatga
    50881 cgggtgaaac agttccaaca gttcttgaag cattcaaagc aaaacttgaa gcgatgacag
    50941 atgatgaatt tgtgacagaa aatatcttcc cacaaattaa agcagtccaa aaagaaacag
    51001 gtattaaagg gaaaaatctt ttcatgccta ttcgtatcgc agtttcaggc gaaatgcatg
    51061 ggccagaatt accagataca attttcttgc ttggacgtga aaaatcaatt cagcatatcg
    51121 aaaacattct aaaagaaatc tctaaataaa gaggatacaa taatggacat ctgggaaaag
    51181 atgtacgaag aagcacagaa actatacaat ccacatgaag tatcagactt tgtttatgcc
    51241 aatcatgttg tagctgcagt agaagcagga gatggacaaa tatttacagg attctgtatg
    51301 gagggaacct gtggtgtttt ccatctctgc gcagaacggg cgaccctctt caatatgtac
    51361 caattttcag gacaaactaa ggttaagaaa gtattagcct ttcgagacaa accaccttat
    51421 ggtggaagtt cagccatgcc ttgcggtgct tgtagagaat tccttttaga gcttaatgct
    51481 gaaaataaag atgcagaatt catgatggac tataatataa gaaaaacagt taaagtcgca
    51541 gaactaatcc cttattggtg gggagaagaa cgtgcttcta agtttaatga gtgatagaag
    51601 agtcagtata attctggctc tttttactat aagttgaaaa aataaaaaaa attagaaaaa
    51661 gtagttgaca aaatttgaaa agactgtata atagtaagag ttgaaaataa caactcaggt
    51721 ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt tcgaatcccg
    51781 tacggactat ggtatgttgc gtcaggagca cttgatgaaa aaaagtttaa aaaa
//
LOCUS       DBEJJV010000011        47397 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.011, whole genome shotgun sequence.
ACCESSION   DBEJJV010000011 DBEJJV010000000
VERSION     DBEJJV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 47397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.011"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            59..439
                     /locus_tag="ACL3GT_000724"
     CDS             59..439
                     /locus_tag="ACL3GT_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516418.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            633..923
                     /locus_tag="ACL3GT_000725"
     CDS             633..923
                     /locus_tag="ACL3GT_000725"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516419.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            974..1666
                     /locus_tag="ACL3GT_000726"
     CDS             974..1666
                     /locus_tag="ACL3GT_000726"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HGR0516420.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1719..4130
                     /locus_tag="ACL3GT_000727"
     CDS             1719..4130
                     /locus_tag="ACL3GT_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0516421.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAVRASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4380..5081
                     /locus_tag="ACL3GT_000728"
     CDS             4380..5081
                     /locus_tag="ACL3GT_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516422.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANCDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5083..7791
                     /locus_tag="ACL3GT_000729"
     CDS             5083..7791
                     /locus_tag="ACL3GT_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HGR0516423.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGIVVGETQIQFYWTYSLLALVLSWLASVLPVYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSETPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7887..8378)
                     /gene="tpx"
                     /locus_tag="ACL3GT_000730"
     CDS             complement(7887..8378)
                     /gene="tpx"
                     /locus_tag="ACL3GT_000730"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HGR0516424.1"
                     /translation="MVTFLGNPVSFTGKQLQGGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8501..9430)
                     /gene="psaA"
                     /locus_tag="ACL3GT_000731"
     CDS             complement(8501..9430)
                     /gene="psaA"
                     /locus_tag="ACL3GT_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HGR0516425.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9462..10310)
                     /locus_tag="ACL3GT_000732"
     CDS             complement(9462..10310)
                     /locus_tag="ACL3GT_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HGR0516426.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10307..11029)
                     /locus_tag="ACL3GT_000733"
     CDS             complement(10307..11029)
                     /locus_tag="ACL3GT_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0516427.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            11320..13212
                     /gene="pepO"
                     /locus_tag="ACL3GT_000734"
     CDS             11320..13212
                     /gene="pepO"
                     /locus_tag="ACL3GT_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HGR0516428.1"
                     /translation="MTRYQDDFYDAINGKWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(13335..13964)
                     /locus_tag="ACL3GT_000735"
     CDS             complement(13335..13964)
                     /locus_tag="ACL3GT_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0516429.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(14304..14546)
                     /locus_tag="ACL3GT_000736"
     CDS             complement(14304..14546)
                     /locus_tag="ACL3GT_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516430.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            14957..17179
                     /locus_tag="ACL3GT_000737"
     CDS             14957..17179
                     /locus_tag="ACL3GT_000737"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HGR0516431.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNLVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            17209..17652
                     /gene="dtd"
                     /locus_tag="ACL3GT_000738"
     CDS             17209..17652
                     /gene="dtd"
                     /locus_tag="ACL3GT_000738"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HGR0516432.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            18443..18826
                     /locus_tag="ACL3GT_000739"
     CDS             18443..18826
                     /locus_tag="ACL3GT_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516433.1"
                     /translation="MGKENVRMRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVR
                     EYVPKKERIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQ
                     AKRIHRAFCIRLCLRAQFLLSNNDS"
     gene            19234..19533
                     /locus_tag="ACL3GT_000740"
     CDS             19234..19533
                     /locus_tag="ACL3GT_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516434.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(19628..20065)
                     /locus_tag="ACL3GT_000741"
     CDS             complement(19628..20065)
                     /locus_tag="ACL3GT_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516435.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(20196..20747)
                     /locus_tag="ACL3GT_000742"
     CDS             complement(20196..20747)
                     /locus_tag="ACL3GT_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0034257 - nicotinamide riboside
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0034258 - nicotinamide riboside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HGR0516436.1"
                     /translation="MISVTNVGISMLSTRFTGKLSKWENYFGIVNTILSGAIDYILGN
                     KAAIITYPVTFLIYTFAIKKWKASQEGRPNQMSQKQVKLAAIIISIIAFLFAFVTNYI
                     GYGGKMNLLAYVTTIAFALSLIANALNALKLTTQWGFWLIYNFVQLTKAGIQGNFANI
                     GKYIFYILNAIGALFVWNDEEVR"
     gene            complement(21041..21691)
                     /locus_tag="ACL3GT_000743"
     CDS             complement(21041..21691)
                     /locus_tag="ACL3GT_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HGR0516437.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEILE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            21803..22645
                     /locus_tag="ACL3GT_000744"
     CDS             21803..22645
                     /locus_tag="ACL3GT_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0516438.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            22721..23158
                     /locus_tag="ACL3GT_000745"
     CDS             22721..23158
                     /locus_tag="ACL3GT_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HGR0516439.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            23226..23528
                     /locus_tag="ACL3GT_000746"
     CDS             23226..23528
                     /locus_tag="ACL3GT_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516440.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(23619..24692)
                     /locus_tag="ACL3GT_000747"
     CDS             complement(23619..24692)
                     /locus_tag="ACL3GT_000747"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HGR0516441.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            24848..25525
                     /locus_tag="ACL3GT_000748"
     CDS             24848..25525
                     /locus_tag="ACL3GT_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0516442.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            25518..26492
                     /locus_tag="ACL3GT_000749"
     CDS             25518..26492
                     /locus_tag="ACL3GT_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HGR0516443.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(26541..28484)
                     /gene="thrS"
                     /locus_tag="ACL3GT_000750"
     CDS             complement(26541..28484)
                     /gene="thrS"
                     /locus_tag="ACL3GT_000750"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HGR0516444.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFEKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(28542..28865)
                     /locus_tag="ACL3GT_000751"
     CDS             complement(28542..28865)
                     /locus_tag="ACL3GT_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HGR0516445.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDPLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            complement(29296..29496)
                     /locus_tag="ACL3GT_000752"
     CDS             complement(29296..29496)
                     /locus_tag="ACL3GT_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516446.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKELYINNLL
                     FFTPLVILIVSLLYSYRFRFSL"
     gene            29734..30363
                     /locus_tag="ACL3GT_000753"
     CDS             29734..30363
                     /locus_tag="ACL3GT_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0516447.1"
                     /translation="MKLAVIAANGQAGKAIVEEVVKRGHEVTAIVRSENKSQSESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            30504..30773
                     /gene="rpsO"
                     /locus_tag="ACL3GT_000754"
     CDS             30504..30773
                     /gene="rpsO"
                     /locus_tag="ACL3GT_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HGR0516448.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            31588..32202
                     /locus_tag="ACL3GT_000755"
     CDS             31588..32202
                     /locus_tag="ACL3GT_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HGR0516449.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(32494..33243)
                     /locus_tag="ACL3GT_000756"
     CDS             complement(32494..33243)
                     /locus_tag="ACL3GT_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HGR0516450.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            33376..35712
                     /locus_tag="ACL3GT_000757"
     CDS             33376..35712
                     /locus_tag="ACL3GT_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0516451.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLMETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDSIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHNYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEQNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            35814..36491
                     /locus_tag="ACL3GT_000758"
     CDS             35814..36491
                     /locus_tag="ACL3GT_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HGR0516452.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            36478..37275
                     /locus_tag="ACL3GT_000759"
     CDS             36478..37275
                     /locus_tag="ACL3GT_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HGR0516453.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            37292..38395
                     /locus_tag="ACL3GT_000760"
     CDS             37292..38395
                     /locus_tag="ACL3GT_000760"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0516454.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDNLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARVTSRAERVGIRAYTSDFSPFFGQVPELAGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            38465..38593
                     /locus_tag="ACL3GT_000761"
     CDS             38465..38593
                     /locus_tag="ACL3GT_000761"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516455.1"
                     /translation="MDRTDEVSSKHCFEVVDRTDEVSNHTHGKATLTWFELDFRRV"
     gene            38696..39715
                     /gene="galE"
                     /locus_tag="ACL3GT_000762"
     CDS             38696..39715
                     /gene="galE"
                     /locus_tag="ACL3GT_000762"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HGR0516456.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            39717..40670
                     /locus_tag="ACL3GT_000763"
     CDS             39717..40670
                     /locus_tag="ACL3GT_000763"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0516457.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(40732..40938)
                     /locus_tag="ACL3GT_000764"
     CDS             complement(40732..40938)
                     /locus_tag="ACL3GT_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HGR0516458.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            40990..41466
                     /locus_tag="ACL3GT_000765"
     CDS             40990..41466
                     /locus_tag="ACL3GT_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HGR0516459.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            41475..42146
                     /gene="cmk"
                     /locus_tag="ACL3GT_000766"
     CDS             41475..42146
                     /gene="cmk"
                     /locus_tag="ACL3GT_000766"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HGR0516460.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEDLLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            42277..42615
                     /locus_tag="ACL3GT_000767"
     CDS             42277..42615
                     /locus_tag="ACL3GT_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HGR0516461.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            42618..43247
                     /locus_tag="ACL3GT_000768"
     CDS             42618..43247
                     /locus_tag="ACL3GT_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HGR0516462.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            43487..44638
                     /locus_tag="ACL3GT_000769"
     CDS             43487..44638
                     /locus_tag="ACL3GT_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0516463.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVMPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            44951..45700
                     /gene="truA"
                     /locus_tag="ACL3GT_000770"
     CDS             44951..45700
                     /gene="truA"
                     /locus_tag="ACL3GT_000770"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HGR0516464.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            45690..46463
                     /locus_tag="ACL3GT_000771"
     CDS             45690..46463
                     /locus_tag="ACL3GT_000771"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HGR0516465.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            46441..46902
                     /locus_tag="ACL3GT_000772"
     CDS             46441..46902
                     /locus_tag="ACL3GT_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HGR0516466.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            47129..47338
                     /locus_tag="ACL3GT_000773"
                     /pseudo
     CDS             47129..47338
                     /locus_tag="ACL3GT_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        13846 a         8765 c        10787 g        13999 t
ORIGIN      
        1 ttttaaaagc aaatatgata caattttatt tgaaaaaaat aaaaaaggag attttattat
       61 gaaattaaaa acacttgctt taattagtgg tatcgtcggt cttgtgggag gaattttact
      121 tcttattggt ccttttgtct tgttgggaac agcggtaaac acagttgcta caactcttaa
      181 tggaggagct actgcagggg ctttttcagg tgttgcctta ctcttgaatg ccttgaagat
      241 tgcaaatctt gttcttggta tcattgctat tgtttactat aaaggagata atcgtgtagg
      301 tgcagctccg tctgtactaa tgattgtttt tggtggagtt agtctcattc cattcttagg
      361 atgggttggg gggattcttg ttattatcgg aggatctcta ttccttgcaa cattgaagaa
      421 attcaaatca gaagaataaa aggtatttta gcatgaaaag aacaaaaaag tttatcggta
      481 taggagtagc tctattatct ctttttcttc tagttgcatg tggaacataa agttcaaagg
      541 atacttcaac aagtaatgat gagaagacag tagcaacatc caatagttca aaagaaacaa
      601 tcactttcga tacaccggtt gtaacagacg atgtgattga atcaatacgc acttatgcag
      661 attatataga tctttataaa aatatttttg atgattattt tactaaagct gaggaaggtt
      721 tcaaaggcac agctatggaa aataatgact cgtttactaa actaaaagag tcaactcaaa
      781 aattattcga tgcgcagaaa aaaaggttaa ataatgaaga tagaatagaa acaactaaaa
      841 acaatgtgat tgccaaacat tgtcaaacag tcctttcctt tttggttttg actagctttt
      901 ttgtgaaaaa ttgtgtaaaa tagaatagat aaacgagggg aaacctcgga aaatttaaag
      961 gagaatccat ctaatggtaa aattggtttt tgctcgccac ggtgagtctg aatggaacaa
     1021 agctaacctt ttcactggtt gggctgatgt tgatttgtct gaaaaaggta cacaacaagc
     1081 gattgacgct ggtaaattga tcaaagaagc tggtatcaaa tttgaccaag cttacacttc
     1141 agtattgaaa cgtgctatca aaacaactaa cttggctctt gaagcttctg accaattgtg
     1201 ggttccagtt gaaaaatcat ggcgcttgaa cgaacgtcac tacggtggtt tgactggtaa
     1261 aaataaagct gaagctgctg aacaatttgg tgatgagcaa gttcacatct ggcgtcgttc
     1321 atacgatgta ttgcctccaa atatggaccg tgatgatgag cactcagctc acacagaccg
     1381 tcgttatgct tcacttgacg actcagtaat cccagatgct gaaaacttga aagtgacttt
     1441 ggaacgtgct cttccattct gggaagataa aatcgctcca gctcttaaag atggtaaaaa
     1501 cgtattcgta ggagctcacg gtaactcaat ccgtgccctt gtaaaacaca tcaaaggttt
     1561 gtcagatgac gagatcatgg acgtggaaat ccctaacttc ccaccattgg tattcgaatt
     1621 cgacgaaaaa ttgaacgtcg tttctgaata ctaccttgga aaataaaaaa ttgtaagtct
     1681 agaattgatt tctaggcttt ttatgttagt atggaagtat gataaggaat aaaaaacaag
     1741 attatgtact ggcctacaag caaccagttt caaccactta catgggttgg gaagaagaag
     1801 ctttaccgat aggcaatggt tctttaggag caaaagtatt tggccttata ggggctgaac
     1861 ggattcaatt taatgaaaaa agtctctggt ctggaggtcc acttcctgat agttcagatt
     1921 atcagggtgg aaatcttcag gatcagtatg tttttttagc tgagattcgg caggctttgg
     1981 agaagagaga ttacaatctg gctaaggaac tggctgagca gcacctaatt gggccaaaaa
     2041 cgagtcaata tgggacctat ctgtcttttg gggatattca cattgagttc agccagcaag
     2101 gtacgacttt gtctcaggtg acggactatc agagacagct gaatattagt aaggcacttg
     2161 tgacgacttc ttatgtctat aagggaacgc gatttgaacg tgaagctttt gcgagttttc
     2221 cagatgatct cttggttcag cgttttacta aggaaggggc ggaaactcta gattttacta
     2281 tagaactatc cttgacctgt gatttggctt ctgatggaaa gtatgagcag gaaaaatctg
     2341 attacaagga gtgtaagttg gatattactg attctcatat cttgatgaag ggaagagtta
     2401 aggataatga tctgcggttt gctagttatc tagcttggga aacggatgga gatattagag
     2461 tttggtcaga tagggttcag atatcaggag ccagttatgc caatctcttc ttggccgcta
     2521 agacggattt tgcccaaaat cctgctagca attatcgcaa gaaactagat ttagagcaac
     2581 aggtgataga cttggtggac acagctaaag aaaagggcta tacccaattg aaatcaaggc
     2641 atatcgagga ctaccaagcc ttattccagc gtgttcaatt ggatttggaa gctaatgttg
     2701 acgcattcac tacagatgat ttgttaaaaa attataagcc acaagaaggg caggctttgg
     2761 aggagctgtt cttccagtat ggacggtatt tattgattag ttcgtccaga gactgcccag
     2821 atgctctacc agctaaccta cagggagtct ggaatgcggt cgacaatcct ccttggaatt
     2881 cggactatca cttaaatgtc aatctgcaga tgaattattg gccagcctat gttaccaatc
     2941 tcctagagac ggtctttcca gtcatcaact atgtagatga tttgcgtgtc tatggtcgtc
     3001 tagcggctgt aaagtatgca ggaatcgtct ctcagaaagg tgaggagaat ggttggttgg
     3061 ttcatactca agcgactccc tttggttgga cggcacctgg ttgggattac tattggggtt
     3121 ggtcaccagc tgccaatgcg tggatgatgc aaaccgttta tgaagcctat tcattttata
     3181 gggaccaaga ctatctcagg gagaaaattt atcccatgtt gagggaaacg gttcgttttt
     3241 ggaatgcctt tttacataag gatcagcagg cgcagcgttg ggtgtcttct ccgtcttatt
     3301 ccccagaaca tgggccgatt tcgattggca atacttatga ccaatctctg atttggcagt
     3361 tatttcatga ttttattcag gctgctcagg aattgggact ggatgaggac ttgttgactg
     3421 aggttaagga gaagtctgat ttactaaatc ctttgcaaat cactcaatct ggtcgaatca
     3481 gggagtggta tgaggaggaa gagcagtatt ttcaaaatga gaaagtggag gcccagcatc
     3541 ggcacgcttc ccatctagtg ggactctatc ctggcaatct ctttagctac aagggacaag
     3601 agtatattga agcggtacgt gctagcctca atgatcgtgg agatggcggc acaggctggt
     3661 ccaaggctaa taagatcaat ctctgggcgc gtttgggaga tggcaatcga gcccataaat
     3721 tattggcaga gcagttaaag acatccacct tgccaaatct ttggtgtagc catcctcctt
     3781 ttcagataga tggtaatttt ggtgctacta gtggcatggc agaaatgtta ctccagtctc
     3841 atgcagctta tctggtacct ctagctgccc tacctgatgc ttggtcaaca ggttctgttt
     3901 caggcttaat ggcacgtgga cattttgaag tgagcatgag ctgggaagat aaaaaactct
     3961 tacagttgac cattttatca aggagtggag gagatttgcg agtttcttat ccagatattg
     4021 agaagagtgt gattaaaatg aatcaagaaa aaataaaagc gaaatgcatg gggaaagatt
     4081 gtatttcggt ggcaacagca gaaggtgatc ttgttcaatt ttatttttaa gaagatgtta
     4141 taaggcagta atttgaaact gccttttaat aaggatttaa gaatataagc agttttcaac
     4201 tagttgaaaa aacgttataa tgataatagg aagtaatact caatgaaaat caaagagcac
     4261 aaactaggaa gctagccgca ggttgctcaa aacagtgttt tgaggttgca gatggaagct
     4321 gacgtggttt gaagagagat tttcgaggag tataatttgt ttgatagagg gtgggtctga
     4381 tggcttatat tgagatgaaa cactgttaca agcgttatca ggttggggac acggagattg
     4441 tggccaattg tgatgtgaat tttgagattg aaaaggggga gctggttatt atccttggtg
     4501 cttcaggtgc aggcaagtca acagttctta accttcttgg gggaatggat accaatgatg
     4561 aaggggaaat ctggattgat ggtgttaata ttgcggatta tagttcccac cagcgcacca
     4621 attaccgtag aaatgatgtg gggtttgttt ttcagtttta taatctagtt tctaatctga
     4681 cagctaagga aaatgtggaa ctggcttctg aaattgtgac agatgccttg aatcctgatc
     4741 aggtcttgac agatgtaggt ctggctcatc gtctcaataa ctttccagcc cagctttctg
     4801 gaggggagca acagcgagtc tccattgcac gcgcggtagc caaaaatcct aaaattctcc
     4861 tttgtgatga accgactgga gccttggatt atcagacggg caagcaggtt ttgaaaattc
     4921 tccaagacat gtctcgtcaa aagggagcga cggtgatcat cgtgactcat aatggagctt
     4981 tggcgcccat tgctgatcgc gtgattcaaa tgcacgatgc cagtgtcaag gatgtggtgc
     5041 tcaaccagca tcctcaggat attgacagtt tggagtacta gcatgatcaa gcgaaaaact
     5101 tattggaagg acttaattca gtccttcaca ggctccaagg ggcgtttttt atccatcttg
     5161 atcctgatga tgttgggatc tctagcctta gtaggcctca aagtaaccag tcccaacatg
     5221 gaggcgacag ctaatgctta tttaacaact gctcaaacct tggatttggc agtcatgtct
     5281 aactatggct tggatcaagc agaccaagaa gaactaaaac agacggaggg cgcagaggtc
     5341 gagtttggct atttgacaga tgtgactatg gataatgggc aggatgccat tcggctgtac
     5401 tccaaaccag agcgaatttc aacctttcag ctaagaaagg gacgacttcc tcagtcagac
     5461 aaggaaatcg ctttggccac tcatttgcaa ggccaataca gcgtgggaca ggagattagt
     5521 tttaaagaaa aagaagaggg tcattcctct ttaaaagacc atacttatac cattactggt
     5581 tttgtggatt cggctgaaat cctctcccag cgagatatgg gctacgcagg aagtggaagt
     5641 gggactctga cagcctatgg ggtgatttta cctagtcagt ttgatcagaa agtctacaat
     5701 atagctcgtt tgaaatatca agatttagca ggtttaaatg ccttttcatc agcttatgaa
     5761 gaaaaatcca agcaacatca ggaagacctt gaacaaactt tatcagataa tggcaaggta
     5821 cgtctgcaac ttttgaaaaa agaaggacaa gagtctctag acaaggggca agagaccctt
     5881 gacaaggctc agactaattt gcaggaaggc aagcgtcgtt tagcagctgc tcaagctcgt
     5941 atacaggctc aagaaagtca actagccttg tttcctcaag ttcagagaga gcaggctagt
     6001 gctcaactta cccaagccaa gcaggaattg ggcaaggaag aggacaaact aaagcaagct
     6061 gaacaaaatc tagcccaaga aaaggaaaaa ttagaaaaac atcagcaagt cttggacgat
     6121 ttggcggagc caaggtatca ggtctataat cgtcagacca tgccaggtgg tcagggctat
     6181 cttatgtata gcaatgcttc atccagtatt cgagcagtgg gcaatatctt tcctgtggta
     6241 ctttatgccg tagcatccat ggtgaccttt acgaccatga ctcgctttgt agacgaagag
     6301 cgaactcatg cagggatttt taaggccttg ggttaccgta gtaaggatat tatcaccaag
     6361 tttctccttt atggactagt agctgggact gtcggaacgg ctctaggtag tatacttggt
     6421 cattatttgc tagccagtgt aatttcaagt gtcattacaa aaggcatagt ggtgggagaa
     6481 acccagattc agttctattg gacctatagc ttactagctc ttgtcttgag ttggttggcg
     6541 agtgtgttac cagtctatct ggtggcttgg agggaacttc atgccgaagc agcccagctt
     6601 ctacttccta aacctcctgt caaaggagct aaaatcttat tggagcgtat cggttttatc
     6661 tggcgtcgtc tcagttttac tcataaggta acagcccgca acatctttcg ttataagcag
     6721 agaatgttga tgacaatctt tggtgtggca ggttctgtag ctctgctctt tgcaggtttg
     6781 ggaatccaat cttctgtagc aggagttccg tctaaacagt ttcaacaaat ccaacagtat
     6841 cagatgcttg tctctgaaac tcctagtgcg accaatcagg acaaggtaga gctagcagaa
     6901 gtgttgaaag ggcaggagat actagcctac cagaaaatct attctaaaac gctagacaag
     6961 gatttcaaag gcaaggctgg tcttcaaaac attactctta tgatgataga gaaggaagat
     7021 ttgactccct ttatccatct tcaacatcat cagcaggagc tgacattaaa agatggcatc
     7081 gttattacag ctaaactcgc ccagctggca ggtgtcaagg ttgggcagac tttagaaatt
     7141 gaaggtaagg aactaaaggt cgctgctatt actgagaact acgttggtca ctttatttat
     7201 atgagtcagg ctagctatga gcaactttac ggacagctac cccaagccaa cacttatctg
     7261 gtctcattaa gggataccag tgcaactagt atcgaaagtc aggcgggctt gcttatgaat
     7321 caatctgcgg tgtccagcgt tgtccaaaat gcttcagcca ttcgactctt cgactctatc
     7381 gctagctcac tcaatcagac catgaccatc ttggtcatcg tatcggttct attagctatt
     7441 gtcatccttt acaatctgac caatatcaac gtagctgaga gaatccgtga actctccact
     7501 atcaaggttc tcggttttca taataatgaa gtcaccctct acatttaccg tgagacgatt
     7561 gtgctgtccc ttgtgggaat cgtacttggt ctggtagctg gtttctattt acaccaattt
     7621 ttgattcaaa tgatttcgcc tgcgactatt ctcttttatc cgcaggtagg ctgggaagtc
     7681 tatgtaatcc cagtggcagc agtaagcatc attttgacct tgcttggttt cttcgtcaat
     7741 tattatctga gaaaggttga tatgttagaa gccctgaaat ctgtagagta aggtagttat
     7801 ttttagctga ttgaacttct atttattaat attcaaaaat cctccgtttc aaagagcagg
     7861 gaactctttg tgacagagga ttttttctat agggctttag cagctgcaat tgcggcttcg
     7921 aagtttggct cagaattgat attatccacg tattcaacgt agcgaatcgt attgtcagta
     7981 tcgaggacaa agactgcgcg tgctaatagg tgccattcgt tgatcaagag ggcataatcg
     8041 cgcccgaaag aatggtcaaa gtagtctgaa agcataatgg cattgtcaag gccttcagca
     8101 ccgcaccaac gtttttgagc aaaaggtagg tccattgaaa cagtcaatac gaccgtgttg
     8161 tccagtccag ctaattcttc attaaaacga cgtgtttgag ttgagcagat gcctgtatcg
     8221 atagaaggaa cgacactcag gacttttttc ttgccatcaa aatcagccag agatttttta
     8281 gaaagatctg ttgtagtaag agaaaaatca agcgccttgt cgccgccttg tagttgttta
     8341 cctgtaaagc tcacaggatt tccgagaaaa gttaccatag gatactccaa tcttttttct
     8401 tccattgtat ctgaaacagt cagaattttc caatgatttg accggaaatg tgggcataga
     8461 aaaaacgcca gctcacatga gaatgacgtt tttcagaggc ttattttgcc aatccttcag
     8521 caatcttgtc aaggttgtat ttcatcatgc tgtagtagct gtcgccttct ttaccttgtt
     8581 ctgcgataga gtcagtaaag atttgtgcgt agattgggat gtttgtgtct tgagaaacag
     8641 ttttcattgg acggtcatcc acacttgatt ctacaaagag tgatggaact tttgtttggc
     8701 gaagtttttc aaccaaggtc ttgatttgtt caggagttcc ttcttcttca gtattgattt
     8761 cccagatgta ggcacttggg acaccatagg ctttagagaa gtatttgaat gctccttcgc
     8821 tggttacaat gagtttcttt tcagcaggga tcttattaaa tttatcctta ctttctttat
     8881 caagtttgtc taacttatca gtatattctt tgagattttt ttcatagaat tctttattgt
     8941 tagggtcttt ggcgctcaat tgtttggcga tatttttagc aaaaataata ccgttttcaa
     9001 ggttaagcca agcgtgtggg tcttcttttc ctttttcatt ttgaccttca aggtagataa
     9061 catcaacgcc gtcgctgact gcgaagtagt ctttgttttc agttttcttg gcattttcta
     9121 ccaattttgt aaaccaagca ttgccacctg tttcaaggtt gataccgtta tagaaaatca
     9181 aatcagcctc agaagttttc ttaacgtctt caggaagtgg ttcgtattcg tgtgggtctt
     9241 gcccaatcgg aacgatacta tgaaggtcaa ttttgtcacc agcaatattt ttagtaatat
     9301 cagcgatgat tgagtttgta gcaacaactt ttagtttttg accagaagtt gtatcttttt
     9361 ttccgctagc acatgctaca agaatgattg cagaaagaaa gagaacgagt aatgtaccta
     9421 attttttcat tagatcctcc aatttattag ggctttgccc cttattttaa caaatgttta
     9481 tttttcagtt tcaaatatcg ttgtttggga gcgataaaga agctaatgag aaagaaacta
     9541 gcagctgtaa gcacgatact agaacctgcc gcaacattaa aactatagcc aataaagagt
     9601 cccaaaactg aagcagtagc tccgaaggtt gaggaaagga aaatcatgct tttcagacta
     9661 ttagcataca gataagcagt tgcagctggg gtaatcagca tggctacaat caggatagtt
     9721 ccgacacttt gcatggctgt cacagacacg agagtcagga gtaccatgag aaggtagtga
     9781 tagaaattga caggcattcc catggcttta gccaagagtt catcaaagga agttatcaag
     9841 agttgcttga agaaaatcca gattaacaag aggatggctg cccccacacc catagtaata
     9901 aacatatccg tatcttggac ggccaggata ttaccaaaaa ggatatggaa aaggtcagtt
     9961 gaacttttag cgacaccaat caagatgata ccgagggcta agaaagaaga aaaggtaatg
    10021 ccgatggcgg tatcgctttt gataatcgag tttcctttga tgtaggtaat gatgatggca
    10081 gctagcaatc caaagacaat ggctccgata aagaagtcaa ggcccaagat gaaggagagg
    10141 gctacacctg gtaagacagc atgtgaaatg gcatctccca tgagtgacat cccgcgtaga
    10201 ataatgaaac atcccacagc tccagctaca atcccgacga caatagctgt tatcaaggca
    10261 ttttgtagga aatggaattt ttgcaatcca tcgataaatt ctgcaatcat aggtcacctc
    10321 cattgaaaaa gagttgatta ccgtaagctt cttttagatt ggtttcggta aaagtttctt
    10381 ttgttggacc aaaggcaatc acttctcgat tgacaagtaa gacttgatcg aagtagtggg
    10441 gaatcttgct gaggtcgtgg tgaacgatga gaaccgtctt cccagctttt ttcaaatctc
    10501 tcagcgtatt catgatgatt tcctcactga cagagtcaat cccagcaaag ggttcatcca
    10561 agaggatata gtcggcttcc tgcaccaaac atctggcaat caagacccgc tggaattgac
    10621 ctccagacag ttgactaatt tgacgttcag cgtagtcagc taggccgacg atttcaaggg
    10681 cctcttgcac tttcttccaa tgtttagcct ttaaacttcg aaagagagga atagagggaa
    10741 atagtcctaa cgagacgcat tccttgacct tgatgggaaa gttgtagtcg atattgattt
    10801 tttgttcgac ataggcaatt cggtgtaagg attttttaac ttccttgtca tcgagaaatg
    10861 cctgaccttg atgtgggata attcccagca taccttttaa tagtgttgat ttcccagcgc
    10921 cgtttggacc aatgatgccg gtaattgttg gtccatggag cactagtgaa atatccttaa
    10981 gtgccaacgt ttctttgtag gagacactga ggttttcgat acgtatcata aacttgtatt
    11041 cctcctgtct cttaatatac attaaaaaaa aaattaagtc aagttaattt ttgaaaaaat
    11101 taaaataata actgaaaaat agattctaaa gataactttc aggataaatt tctaaattat
    11161 aaaacgcata gtatcaagtg taaaaaactt ggaattatgc gttttatcat ggaaagattt
    11221 tttataatag ctaaaaaata atagttaaat ggttattaat tgcattccct agtgattttt
    11281 gttaagataa atgcaaatac aaatgaaagc gagaacaaga tgacacgtta tcaagatgat
    11341 ttttatgatg ctatcaatgg aaaatggcaa cagacagctg aaatcccagc agataagtct
    11401 caaacaggag gttttgttga tttagaccag gaaattgaag acctgatgct ggcgacaaca
    11461 gacaagtggt tagcaggtga agaagtgcct gaggatgcta tcttggaaaa ctttgtcaaa
    11521 taccaccgcc tagttcgtga ttttgacaag agagaagctg acggtatcac acctgtctta
    11581 ccactcctta aagaattcca agaattggaa acttttgcgg attttacagc taaactagca
    11641 gagtttgagc ttgcaggaaa accaaacttc cttccttttg gtgtatcgcc agactttatg
    11701 gatgctagaa tcaatgttct atgggctagc gctccaagca caatcttgcc agatacgacc
    11761 tactatgcag aagaacatcc tcagcgcgaa gagctcttga ctctttggaa agaaagcagc
    11821 gcaaatctcc tcaaggctta tgatttctct gatgaagaaa ttgaagactt gctagaaaaa
    11881 agacttgaat tggaccgccg agttgcggca gtggtgctct ctaatgaaga aagttcagaa
    11941 tatgctaaac tctatcatcc atattcttac gaagatttca agaaattcgc gcctgcccta
    12001 cctttggatg acttcttcaa agcagttatt gggcaattac cagacaaggt tattgtagac
    12061 gaggaacgtt tctggcaagc agcagagcaa ttttacagtg aggaagcctg gtctctcctt
    12121 aaagcaacct tgattttgag tgttgtcaat ctttcaacca gctatttaac agaggatatc
    12181 cgtgttttgt ctggtgccta cagccgtgcc ctttctggag ttccagaggc aaaagataag
    12241 gtcaaagcag cttatcatct agcacaggaa cctttcaagc aagccctggg gctttggtac
    12301 gcccgtgaga agttctctcc agaagccaag gcggatgtgg agaaaaaagt ggcaaccatg
    12361 attgatgtct ataaggagcg tctgcttaag aatgactggc tcactccaga aacctgtaaa
    12421 caggctatcg tgaagctcaa tgtgatcaaa ccttatattg gctatccaga agaattgcct
    12481 gcacgttaca aggataaggt agtgaatgaa actgccagtc tttttgagaa tgctctagcc
    12541 tttgcgcgtg tggaaatcaa gcacagttgg agtaagtgga accagcctgt agactataag
    12601 gaatggggca tgcctgctca tatggtcaat gcctactaca atcctcagaa gaacctgatt
    12661 gtctttccag cggccatttt acaggcgcct ttctatgact tgcatcagtc atcttctgct
    12721 aactacggtg gtattggggc agtgattgcc catgaaattt cccacgcctt tgatactaac
    12781 ggggcttcct ttgacgaaaa tggtagcctc aaggattggt ggacagagag cgactatgct
    12841 gccttcaagg agaaaacaca aaaagtcatt gaccaatttg atggacagga ttcttatgga
    12901 gcaaccatta acggtaaatt gactgtatca gaaaacgtgg ctgacttggg aggaatcgca
    12961 gcagcgcttg aagcagctaa gagagaagca gacttctcag cagaagagtt cttctacaac
    13021 ttcggtcgca tctggcgcat gaaaggtcga ccagaattta tgaaactttt ggctagcgtc
    13081 gatgtgcacg caccagccaa actccgtgtc aatgtgcaag taccaaactt cgacgatttc
    13141 tttacaacct atgatgtcaa agaaggagac ggaatgtggc gttcaccaga ggagcgcgtg
    13201 attatttggt aatacaaaaa atctagtcat cagaaaaaag gcatccaatc acgtgtgaaa
    13261 accttgatag gatgcctttt gtaatagaaa gatttgctgg atagtttact taaatttcga
    13321 ttgtcatcat cttgctagaa aaagggattg aaggcctttt cgtgagcgat agtagtagct
    13381 ggaccatgtc ctggatagac atcgtagttt ggtagggtga agagttgggt ctggatacta
    13441 tgaaggagtt gctccatgct accagtcgga aggtcggtcc gtccgatagt ttcgcggaat
    13501 agagcatctc ccgtcaagac taggtgagca tcaggaaaga ctagggaaac accaccgata
    13561 gagtgccctg gggtcggtag aaccttaaaa cgaaattcct ctagttggta ttcttcgtga
    13621 aagacaaagg tgtgttctgc aggttttgtg accacatctg ccatatcatc gtggcgaggg
    13681 agaccggaga gattatcgac aggagtgtag agccagctgg cttcgctctc tgcgatatag
    13741 acaggaggat tgccaaacgt ctcgcgaacc aagtccagac tcatgatatg gtcataatgg
    13801 gcgtgggtca agagaatagc acagatcggt ttgttgatct tctcgattgt ctgacgaatg
    13861 gcttcccaat gactaccagg atcgacgacg atgaggtgct tttcgccttc tagataatag
    13921 gtattttcat aggcaacagg attcacggtt ttatggattt tcatactaac tccaatctca
    13981 aagaatgtac taatactctt cgaaaatctc ttcaaaccgc gtcaacttta tctgcaacct
    14041 caaagcagtg ctttgaacag cctgcggcta gctttctagt ttgctctttg attttcattg
    14101 agtataaatt aagtatagca cagttaggga gaataggtaa ggatttaaaa tgaacttaaa
    14161 aaccagcatg actagatgaa gacaggctgg ttatcaattt atcaatattg gaaaggtgtc
    14221 aattgccctt cataggttgc ataaactccg tcattagctt gtttgataga cgtgatgttt
    14281 agagtgctac cgtagttggc ttctcatttg tcgctatatt cactataagt tatcctactg
    14341 ggcaggttct ggtcgttagc atagtattga acgagttttt tatagctttg ctggctgaat
    14401 aggaacaggc agcaaactcc taacattagg agagcaaaga tagaaatagc agttttttca
    14461 taggtattct ccttataaac taaaggatag aagaaagtat cttgaggatt tttatactct
    14521 tcaaaaatct cttcaaaccg cgtcaacgtc gccttgccgt atatatgtga ctgactttgt
    14581 cagtcttatc tacaacctca aagcagtgct ttgagcaacc tgtggctagt ttcctagttt
    14641 gctctttgat tttcattgag tattaattcc aaaatccagt caaggtacca gtgtatgtga
    14701 tacgagttcc accgtttatc tttcgtatct tcaatggaat tggggaaatc agaaagtctt
    14761 tgggttacaa tatggtttcc gttcttctat ctctccttct atcacctaag tttaaaatct
    14821 aacttcgtag tatattatgg gccaataatt cagaattatc aagcaatttt gaattatttt
    14881 tttcttattc tgttccaatc tagttttcat attcttaaaa aagtgataaa atggtaggaa
    14941 gaattggaga gtagagatgc cgaaagaagt gaatttaaca ggcgaagaag ttgtcgcttt
    15001 aaccaaagaa tatttaacgg aagaggatgt tcattttgtc cataaggcct tggtctatgc
    15061 tgttgaatgc cacagtggtc aatatcgcaa atcaggcgag ccttatatca ttcaccctat
    15121 ccaagtggca ggtattttag ctaagctaaa gctggatgct gtaacagtag cttgtggatt
    15181 cttgcatgat gtggtggaag atacagatgc gaccttggac gatttggaaa gagagtttgg
    15241 tcctgatgtg cgggtgattg ttgacggagt taccaagctt ggcaaggtcg agtacaaatc
    15301 gatcgaggag caattagcgg aaaatcatcg caagatgctc atggccatgt ctgaggacat
    15361 ccgcgttatt ttggtcaaac tgtctgaccg cttgcacaat atgcggaccc tgaaacatct
    15421 tcgaaaagac aagcaggagc gtatttccaa agaaaccatg gaaatctatg ccccacttgc
    15481 ccatcgtttg gggatttcca gtgtcaaatg ggaattagaa gacttgtctt tccgttatct
    15541 caatccaacg gagttttaca agattaccca tatgatgaag gaaaagcgca gggagcgtga
    15601 ggccttggtg gatgaggtag tcacaaaatt agaggagtat acgacagaac gtcacttgaa
    15661 agggaagatt tatggtcgtc ccaagcatat ttactcaatt ttccgcaaaa tgcaggacaa
    15721 gagaaaacgg tttgaggaaa tctatgatct gattgctatt cgttgtattt tagataccca
    15781 aagtgatgtt tatgccatgc ttggttacgt gcatgaattt tggaaaccga tgccaggtcg
    15841 cttcaaagac tatattgcca accgcaaggc caatggttat cagtctatcc atacgactgt
    15901 ttatggacca aaagggccga ttgaattcca gattcgaacc aaggaaatgc acgaggtggc
    15961 tgagtacggg gttgcggctc actgggctta taagaaaggt ataaaggggc aagttaacag
    16021 caaggaatca gctattggaa tgaactggat caaggagatg atggagctcc aagaccaggc
    16081 tgatgatgct aaggaatttg tggactctgt taaggaaaac tatttggctg aggagattta
    16141 cgtttttacc ccagatggag ctgtccgttc ccttcccaaa gattcaggac cgattgattt
    16201 tgcctacgaa atccatacca aggtcggtga aaaagcaact ggtgccaagg tcaatggccg
    16261 catggttcca ctgacaacca agttaaagac aggggatcag gttgaaatta tcgccaaccc
    16321 gaactccttt ggacctagcc gtgactggct caatatggtc aagactagca aggcgcgcaa
    16381 taagattcgc cagttcttta aaaaccaaga taaggaattg tctgtcaaca agggtcgtga
    16441 gatgctgatg gctcagttcc aagaaaatgg ctatgtggca aataaattta tggacaagcg
    16501 ccacatggat caagttctgc aaaagaccag ttacaagaca gaagactccc tctttgcggc
    16561 cattggtttt ggggaaatcg gtgcgattac cgtctttaac cgtctgactg aaaaggaacg
    16621 ccgtgaggaa gagcgtgcca aggccaaggc tgaggcagag gagcttgtca aaggtggcga
    16681 ggtcaaggtt gaaaataaag aaactctcaa ggtcaagcat gaggggggag tggttattga
    16741 aggtgcttct ggtctcctag tgcggattgc taagtgttgt aacctcgtgc ctggtgacga
    16801 tattgttggc tacattacca agggtcgtgg tgtggctatt caccgtgtgg actgtatgaa
    16861 cctgcgtgcc caagaaaact acgagcaacg tctccttgat gtggaatggg aagaccagta
    16921 ctctagctca aataaggagt atatggccca tatcgatatc tacggtctca accgtacagg
    16981 actgttgaac gatgtactgc aagttctttc aaatacaacc aagaatattt caacggtcaa
    17041 tgcccaacca accaaggata tgaagtttgc taatatccat gtgtccttcg gtattgccaa
    17101 cctctctaca ctgaccacgg ttgtcgataa aattaagagt gtgccagaag tttactctgt
    17161 caaacggacc aacggctagt tgtcctagct cttactagaa aggctattat gaaaatcatt
    17221 atccaacggg ttaaaaaagc ccaagtgagt atagaaggcc agattcaggg aaaaatcaat
    17281 cagggacttt tattgctggt tggtgttgga ccagaggacc aagaggaaga tttggactat
    17341 gctgtgagaa aactggtcaa tatgcggatt ttttcagacg cagaaggcaa gatgaacctg
    17401 tctgtcaaag atattgaagg agaaatcctc tccatttctc agtttaccct ctttgcggat
    17461 actaagaaag gcaatcgtcc agcctttaca ggggcagcta aacctgatat ggcatcagac
    17521 ttctatgatg ctttcaatca aaaattagcg caagaagtgc ccgttcagac aggtatcttt
    17581 ggagcagata tgcaggttga gctggttaat aacggacctg ttaccattat cctagatact
    17641 aaaaagagat aagaaagacc aagcccagtc ggcttggtct ttctcatcga tcataaaata
    17701 ctccaaaaag aaatcggttc ttgatatgct tgggggaagt ctcttttcag gctttggcag
    17761 atgcgatagg aagggatgag atgtcctagg atgaggagag ttccctgaag gaaaagtgga
    17821 atatcactta aagacaccaa ggagagaatc atcaggctat cccataggaa aatttgtaaa
    17881 gcaaaacgcc agaatctcgg tctaatctgg gaatagagtt gactaaagtg gtcacaaagt
    17941 tggtttgaaa gataggtcaa tagcacggga tgaaagaaaa tgagccaacc actataaatc
    18001 aaaatccagt cccaagtaag cccccctttt aaatgtcaaa aataccagca tgattccatc
    18061 aatgacaagg agttgaatgg ttttgatgaa gatgattttt ttcatgctaa aacctccttt
    18121 tccttagaga cactccccta caggtatttt agaatgtata ttgcttagat attccttatt
    18181 ttattagctt tttaaggtat taaagtagtt atataagttt atgaagggta tcctatcctg
    18241 cacggctaat tttgagttcg aaactgagga gtttataact caaaatttcg attaaatcag
    18301 catttaacga tagtatgttt gtcataaaat gataaatttt tagattgtgg aatttttttc
    18361 aacttaattc ttgatttttt ttctaaattg ttatatactt aatttacggg ataacagaat
    18421 cccgtcagaa aggggtgata atatgggaaa agagaatgtt agaatgcgtt tagcgtctga
    18481 atccagacag atattagata agcttaaaga tgatgtttac aataaattag gctatgaagt
    18541 aagctattcc agtattgtta gtcaagctgt tagagaatac gttcctaaaa aagaacgtat
    18601 agattggata aaattaaaag agacagctat acctttttca tcgttaaaac agagcaataa
    18661 ttgggagtac cagacatcac ttatgttaga gaaagatgta ttaatcttac tgtctgaact
    18721 acaaaatttt ttcttagatg tcttccaagc gaaacgtata catagggcat tttgtatacg
    18781 tctatgtttg agagcgcaat ttttattaag taataatgat tcttaatact atcaatatta
    18841 atgcggagtg taatgctccg caaaaataaa acctattacg ggataaaaac actactttat
    18901 ttaggatgga aataagaacg tattttttac taatattgtt tagaaaggag tttctttatg
    18961 acaccagaag aacaaactgc tttggaatac ttttatgagg aactcgagag ttacggtgaa
    19021 gatgagcaag gagaggtctt tgatttgtat gataattaaa tcatctccat agtttctgag
    19081 aataattgag aaactatact ctaaatcata ggtttatgta aagctagata tacacaaaag
    19141 gaggtacgaa tgaagatgaa agctagagct tcaccgttga attgattttg tttctagaaa
    19201 aaatcaataa ttagaaaaat acgaggtaaa aaaatgaata gaaatgtact aaattttctg
    19261 cgaacagaaa gtgctgaaag agttagtctt tatatagaca aggctaatag attggagggc
    19321 gatgtaactc tactcgcacc tagttctcaa gatttggaag atattaaaaa tgctatgttt
    19381 tccaatccta atctcgagct aaaagtagcg agactggatg tgatgaagaa aatagcatat
    19441 gcttctacaa gaaatcatta tttaacaggg gctacgattt ttggggatat ttcgaaagga
    19501 acatacaatt gtgatcctaa aagttatgtc taatataagg gaggttaatc cctccccttg
    19561 tttttgaaaa tcgaaaggaa aagtataaaa atgaaagtta atgaatattt ctggagaacg
    19621 agctgtctta tactaaaaaa gaagaaatcg ataaaatagt atacgtgtta gagatgtgtt
    19681 tgtcgtaaaa gtctggatag ttttctctta ggtagtcagc tgtcatataa taaaaagtag
    19741 aatggcaagc agtgatgatt ggcataagag atgaaaaacg ctgagaacta atgaaggcta
    19801 agagaacaaa aaatagaaaa tcaatggtga gaacccctaa atagtagaag cgaatctttt
    19861 tattgatttg aggataaatc tcagcgaatt gatgtttgag tcggacgacc aagagaaata
    19921 gcaggagtcc ttgagcaagg aagaaaatta aaccagagag caagagccac tcaaaagatg
    19981 tctcgagtct agtgataaaa aatgcaaata gtagcaaatc aataactgca attgctataa
    20041 aatggattct atagagtttt ttcatgacaa gacctccctc ttttatctaa cttcattcta
    20101 ctctaaaaga atgggagtta caactaaaat gataaaaata gcagagggga gattctctta
    20161 agttggctag tattctttat ttgagtttcc ttctattatc taacttcttc atcattccag
    20221 acaaataaag ctccgattgc attgaggata taaaagatgt atttaccgat attggcgaag
    20281 tttccttgaa taccagcttt tgtcagctga acgaaattgt aaatcaacca aaagccccac
    20341 tgagttgtta gttttaatgc attcaaagca ttggcaatga gggacagtgc aaaggcaata
    20401 gttgttacgt aggcaaggag attcatcttg cccccatatc cgatatagtt ggtcacaaag
    20461 gcaaagagga aggcgatgat ggaaatgatg atggccgcca attttacctg tttttggctc
    20521 atttggttgg gtctgccttc ttgcgaagct ttccatttct ttatagcaaa ggtataaatg
    20581 aggaaggtga cgggataggt aatgatggcc gccttatttc caaggatata atcaatagca
    20641 ccggacaaaa tggtattaac aataccaaag taattttccc atttgcttaa tttccccgtg
    20701 aaacgagtgg acaacatgga aatcccaacg ttggttacgg aaatcaatcc aaagggtaca
    20761 agagctgtcc atggtcccca gtctacaaat ttatcgaggc gtgagttgag gtaaccagat
    20821 gcaatcgcaa tccaacgacc aaagcaaccc cgaagaggtc aaactattta gatgtagcaa
    20881 aaatttttag tgattttttc ataggttaaa ctacctttct ttttttcaaa tattctccca
    20941 ttttttttca aatattctac caccaaatga aagtaaaata aaatgataga aataaaaccc
    21001 tgaaaataaa actttcaggg ttggtagggg acttgagaaa ttagttgatt ttctcgacat
    21061 agagttgttt tgcaatgtcc atattcactt gtaaatcctc gtcgttactg aggatagtga
    21121 aggtattgct gaagccatca aactgcttaa cttggagctg gtcaccgatg tgaagtgagt
    21181 gcttgtccag ataatggaga atgtcaaaac tatcgtgcat ccgagtcagg cggtaggcgc
    21241 cagcttcctt gatatcagct agtgggaggt tattgatttc aacgaggagt tctcccttgg
    21301 caggaatagt tcctccgtgg gggcaggttt tagggaaacc tagcagttta tctagtcttt
    21361 ccacgaacag gtcagagaca gtgtgttcca agatctcagc ttcctcgtga atctggtcac
    21421 ttgtatagtc taaatgatga actagaaaaa cttcaatcaa gcggtgctta cgatagagct
    21481 cagagaccag tttgagaccg aggtcagtca gtagatagcc acattccttg tcctttagga
    21541 tgagattttc acttttcatt cgtttgatca tttcagttac ggcaggggga gagacttgca
    21601 tgcgagccgc aatttccttg ttggtaatct tatgcaggtc tatgccaatt tcataaatac
    21661 attttagata gtcttctttg tttggggtca ttcgtttcct cttgtctaat atctttatct
    21721 agtatatcaa aaaaagctag atttctctag ctgtgacttt ttatgttata cttattgcaa
    21781 gagaaaaaac gaggagatgg atatgacgaa aatagctctt ctttcagata ttcatggaaa
    21841 taccaccgcc ttggaggctg ttttggcaga tgctcggcag ctaggagtgg atgaatactg
    21901 gcttttggga gatattctca tgccagggac agggcgtaga aggattttgg acttgttgga
    21961 tcaactaccg attacggcta gagttttggg aaactgggaa gacagtcttt ggcatggtgt
    22021 ccgtaaggaa ttggatagta ctcgccctag tcaacgctat ctcttgcgcc agtgccagta
    22081 tgttttagag gaaatttccc tagaagaaat tgaagtgctc cacaatcaac ctcttcaaat
    22141 tcatcgtcag tttggggatt tgacagtggg aattagccat catctgcctg ataagaactg
    22201 ggggcgagag ttgattcata ctggcaaaca agaggaattt gaccgcttgg tgactcatcc
    22261 tccctgtgat attgctgttt atggacacat tcaccagcag ttgcttcgtt acgggactgg
    22321 tgggcaattg attgtcaatc cgggttcgat tggccaacct ttctttttgg acgctcagct
    22381 acggaaggac ttgcgggccc agtatatgat tttggagttt gatgacaagg gcctggtaga
    22441 tatggacttc cgacgggtag attacgatgt ggcagctgaa ttgcagctgg ctaaagacct
    22501 gagacttccc tattttgagg tttactatga aagtctggtc aatgggatcc accatactca
    22561 tcatcaggaa tttttgagag aattggctca gaaagagggt tgcgatcggg agttagacga
    22621 ctggttgaaa agtggtaacg attgacatta caactaaaaa gggtataata atagaaaaag
    22681 aagagtagag gcagggtagc ctcgtaaaaa ggagaagagg atgcaaattc caagtagatt
    22741 taccattgcg actcatatgc tgataatcat tgccctcgag gggaagaaaa gcaaggtgac
    22801 cagtgatttt ctggctgcta gtgtcggggt caatcctgtc attatcagaa agatcttgtc
    22861 ccagttgaag aaggcagagc tgatttcagt agcgcgtgga acgggcggaa cagatattgt
    22921 caaggacctt aaggatatta gtcttttaga tgtttatcag gcggtcgaat gtcttggtaa
    22981 gacaggtcaa ctcttcagtt tccatgacaa tccgaatcca aattgccctg taggagctca
    23041 tattcatgat gttttggatc aaaaattgga gagaattcag ttgactatgg aggcagaact
    23101 tggtcaaacc agtctagaaa aagtcgtggc cgatgcagag agtcagatga aggattaaga
    23161 gggataaatg ccctcttttt tctttggata attatgataa aatgtagcta ttaaaggagt
    23221 aagaaatgta tctcgttata ggaattgtat tagcctttat agtgtcattt tggaaggata
    23281 atagaagttt gtggaatcca gtattatttt tattatccct catttcaagt tatttttatc
    23341 tatcctacct tttttataaa aatggatacg agaatgttca gttagctttt tatgtatttg
    23401 cctttgtctt acttcctttt ttgctttttc taagtggcat ctttttaatc tataatgggg
    23461 tcattttgtt gaagcgagag ggacgttcca agccccatta tctctcaatg ctctttgatt
    23521 tttattgact attagattct atttaaaaag acttagaatg cacatgaaag tatgtattct
    23581 aggtcttttg ttttgtatac atttaatttt caagagtatt atctattttt ccatgcctgg
    23641 taacgagtat caatcaataa ctgggtaagg cgacccaagg tttctctttc ttctggagtg
    23701 agggattgag cttggacaaa gagatgatga atgtattcaa gcgcctttaa ggaagccaag
    23761 tcattgatag agctaatacc agcctcaaga atagtgccaa agaagaggtc gaagtagagc
    23821 tgaagttctt cgtcagggac tgtggccacc cattctttaa aggttgtgtc tacttgctgg
    23881 ctatcactgt tggtcttatc cagttggacg aagtgcttgt cctcaatctg ccaactaaag
    23941 gtatcgtgct gggcgatgcc acccagggca gtactctgaa cgatgatttg gtgagcagga
    24001 atttccagca tcataccgat aatggaacct tgtggaatga atatcttgct tctatccatt
    24061 atcctttgat aacccgcagt ctgtgtcaat tcttgatgga gaccaggtgc atcaaatgta
    24121 taaactgctg tgatctgatt ttgcaaactt tgctcaattt ggctagcagc atagatagcg
    24181 agatttcctc ccttggaatg cccagctaga ataacctttt gcttaggatg atgggcaaaa
    24241 aagttcttta aatagcgaag ggcgtgcttt tgagcaggaa tttccttcat ataggtcagg
    24301 tggaaatctt ccttccagcc aatgatactg tcatctgtcc cacgaaagac aatcagatag
    24361 gtatcgaggc tgacacgata agtcatagcc gcaaattgct tttgcagttc agggtcgatg
    24421 tcgttgataa aatgggagag tttgcaattt ttgaagcgct tgtgttgagc caatttatct
    24481 aataattgaa ggcgattttt gctagtaagc atggtgggct ctcttggaac ctgaggtgct
    24541 agatctaaaa gacgttgagg aagtgtggag accagattat caaaggagag gtaggtgatt
    24601 tctattaagg ttagaatgtc taactcattc aagggaaggt cgtaataaga atcatatgcg
    24661 acatctttca gatagtcaaa aatattggcc ataagagctc ctttcttttt atttatctta
    24721 gcaaatttcc ctcaaattag ctagtagcat agcctgtttg cactggctaa aaacaggcta
    24781 tttcaaattc agtttcagac catctagcat ggaaaaatct gttataataa tggaaaagga
    24841 gaagcgcatg cacaagattt tattaataga agatgatcag gtcattcgtc aacagattgg
    24901 gaaaatgctc tctgaatggg gatttgaagt ggtcctggta gaagacttta tggaagtttt
    24961 gagtctattt gttcagtcgg aacctcatct ggtcctcatg gatattggtt tgcccttgtt
    25021 taatggttat cactggtgtc aggaaatccg caagatttcc aaggtaccta tcatgtttct
    25081 ttcttcgaga gaccaggcta tggatattgt catggcaatc aatatggggg cggatgactt
    25141 tgtgaccaag ccttttgacc agcaggttct tttagctaag gttcagggct tgttgcgtcg
    25201 ttcctatgag tttgggcgtg atgagagttt gctggaatat gctggtgtta tcctcaatac
    25261 caaatccatg gatttacatt atcaagggca agtcttgaat ttgaccaaga atgaattcca
    25321 gattttacgc gtgttatttg agcatgcagg caacatcgta gcacgtgacg acctgatgcg
    25381 ggaactttgg aacagtgact ttttcattga tgataatacc ctctctgtca atgtggctcg
    25441 tttgcgtaaa aagttggagg agcagggatt ggtaggattt atcgagacca agaaaggaat
    25501 agggtacgga ttgaagcatg cttgattgga aacaattttt tctagcctat ctgcgctccc
    25561 gtagtcgtct ttttatctat ctgctttctt tggcatttct tgtcttactc tttcagtttt
    25621 tatttgccag tctaggaatt tacttcctct actttttctt cttgtgttgc tttgtaacca
    25681 tcttattttt cacttgggac atattggtgg aaatgcaggt ctatcgccag gaacttctct
    25741 atggagagag ggaagccaag tctcctttgg aaatagcttt agcagaaaaa ttagaagcgc
    25801 gtgagatgga actctatcag cagaggtcaa aagcagaaag aaaactgacg gatttgctgg
    25861 attactatac cttgtgggtc catcagataa agacccccat tgcagccagt caactcttag
    25921 ttgcagaagt ggtcgaccgc caactgaagc agcagctaga acaggaaatt ttcaaaatcg
    25981 actcttatac caacctagtt ttacagtacc tgcgtttaga aagtttccat gatgatttgg
    26041 tcttaaagca ggttcaaatt gaggacttgg tcaaggaaat aattcgtaaa tatgctcttt
    26101 tctttattca aaaaggctta aatgtcaatc tacatgacct tgataaagaa atcgtgacgg
    26161 ataaaaagtg gctgctagtg gttattgagc aaatcatctc aaacagtctc aagtacacca
    26221 aggaaggtgg tctggagatt tatatggatg accaagagct ttgtatcaaa gatacgggaa
    26281 tcgggataaa aaacagtgat gtcctccgag tatttgaacg tggcttttca ggatacaatg
    26341 gccgtttgac ccagcagtcc tctggacttg gcctttatct atctaagaaa atttctgaag
    26401 aactggggca ccagattcgt atcgagtctg aggtcggaaa aggaacgaca gtgcggattc
    26461 agtttgctca agtgaactta gtccttgagt aaaaatagat gagaaaaagc ctccagattg
    26521 gaggctttta tgctagactc ttatttctca acgcgtgatt tgttggcgat atcagctagg
    26581 atagcttgaa caaaattatc aactgagaca gtttgtgttt ctttttggcc gtagcgacga
    26641 acgttgactg tttcgtcttc catttctttg tctccaacaa ttaattggta aggaatcttg
    26701 ctggtttgtg aagcacggat cttgaactgc attttttcat tgcgctcatc tacgtctgca
    26761 cggacaccgc ggtcacggag tttcttggct acttcccaag cgtagtccac gtgtttttcg
    26821 ttagatactg ggataagggt tacttggtgt ggtgccagcc atgttgggaa ggcacccttg
    26881 tagttctcaa tcaagatagc tgtgaagcgt tccatagttg agataacccc acggtggatc
    26941 atgactggac ggtgatcttc gccatcagct ccgatgtatt tgaggtcgaa gcgttctggc
    27001 aacaagaaat caagttggat agtagaaagg gtttcttctt ttccaagggc agttttaatc
    27061 tggatatcca attttggtcc gtagaaggcc gcttcacctt cggcttcaaa gtagtccacg
    27121 cccatttcat caagagctgc acgaagcatg gtttgggcat tttcccacat ctcatcgtta
    27181 tcaaagtact tatgagtatc ttgagggtca cgaagagaga ggcggaagcg gtagtcagtc
    27241 aagttgaagt cttcataaac atcgataatc aactgaaggg cacgttggaa ttcttcttgg
    27301 atttgttctg gagtaacgaa taggtgaccg tcgttgagtg acatttcacg tacacgttga
    27361 aggccagtga gggcaccaga tttttcgtaa cggtgcatca taccgatttc agcgatacgg
    27421 attggcaatt cacggtaaga gtgaacatgg tgtttgaaaa cttggatgtg gtgcggacag
    27481 ttcattggac gaaggacaaa ttcttccccg tcacccatgt ccatggttgg gaacatgtct
    27541 tcttggtaat gatcccagtg gccagaagtc ttgtaaagct caacagaagc aagtggtgga
    27601 gtgtagacgt gttggtagcc agaagccaac tctttgttta cgatgtagcg ttccaattca
    27661 cgacggatag tcgcaccatt tggcaaccag aatggcaaac cttgtcccac ttcttgtgaa
    27721 atcataaaga ggtcaagctc tttaccaagt ttacggtggt cacgttcctt agcttcttca
    27781 cgcatttgaa ggtagttttt caagtctttc ttttcaaacc aagctgtacc gtagatacgt
    27841 tgcatcatag cgttgtcgct gtttccacgc cagtacgcac cagctacatg gagaaggtgg
    27901 aagatttgga tacgacctgt tgatggaacg tgaggtccac ggcagaggtc tacatattca
    27961 ccctgacgat agatagtcaa accgccttcg tcttctgagt gttcttcaat caattccaac
    28021 ttgtaagggt catttttgaa gatttcacgt gcctcgtctt tagtcacttc ttcacgaata
    28081 gatgggaagt tttctttgac gattttttgc atttcttctt cgatacgagg aaggtcttcg
    28141 ttagagattt gaccagctgt gttgtcagta tcgtagtaga aaccatcttc gatggctgga
    28201 ccaactccca agtgaatgtc tgggaaaaga cgacgagctg cttgggcgaa caagtgagct
    28261 gctgagtggc gcaagattgg aagggcatct tcgtgatcag gtgtcacaat ttcgatgctt
    28321 ccatcttcag tgatagcgcg agtagtgtcg atgagtttgc cgttgaattt accagccaag
    28381 gcttttttag ctagggaatt gctgatagat tgggcaattt caaaagttgt tacgccagat
    28441 tcgaattcac gaacagcgcc atctgggaaa gtaatgttaa tcatgatgtt ctcctttttt
    28501 attatttcat agtttctaag cattgatttt ttatcatcag actacttcca agtcctaacg
    28561 ttcaattgct tttctttatc agagaggaag ttttccattt ccgtcagaat gtctatatcc
    28621 aaacgttgag aaagttctaa tagccaccag atattttctg aaagtttttg ttccagtgtg
    28681 tagggtgttt catcatagta gcgtccttgc tttgtcatca ccagtcgttg gaaatttcca
    28741 atatcattag ataaagccaa ggggtcttct tctaccgtcc acttggaatc atgatgctta
    28801 acttccagtt cgtgataagc ttgtcggatt gcccaactgc gctccactaa ttcttgcaac
    28861 tccataatta gtatcctaat aaaaaaatgc gacatcctcg aaaggacgtc gcaacgtggt
    28921 tccaccttca tttatgtacc tcaaaagaga gggacacctc tgattggctc taacgtggcc
    28981 accgttttat gttttcataa aaaactcaag agtagtatca gtttagactt cctatgcgtt
    29041 tccagcaacc acgcactctc tagtagaaag ggactaagtg acttgtctct atggattatt
    29101 atagcatgat tgtgagattt ttcaaggatt ttgtgaaagt tttttgtttt tcattttttg
    29161 tagaatatgc ttgatgctaa taccagaatc catgcccacc agagcaactg tttcatagat
    29221 tagcaagtaa attagtataa actcaccaaa ggttatgata gtaaagtaaa agagcagtcc
    29281 gttaccaact aaccatcaaa gtgagaaacg gaaacggtag ctatagagta acgatacaat
    29341 caagattacc agaggtgtaa agaagagaag attgtttata tagagttcct tgagtgtaag
    29401 ggggtcagaa acaactagta agaacaactc ataaagtggc caataaaaga ataatatgac
    29461 cagatagtag gggagatggg aatagaatct acgcatgata atcacctcgt tttaaaaaaa
    29521 cagacaactt agatctcttg ctatgattat tatagcatgt ttaaaacaag aaagtaaatt
    29581 tgttggcaaa gaagattttt ttttcactag aatcatggtt agttttcttg gtagaaatat
    29641 tttgataata attaagcaaa actattgaca ttgattatta agagtgtcac aattgttgta
    29701 actaaaataa ttacaataag agaggtataa aaaatgaaac tagcagttat tgcagcaaat
    29761 ggacaagcgg ggaaagcaat tgttgaagaa gtagtcaaac gaggacatga agtaacggct
    29821 attgttcgtt ctgaaaacaa aagtcaatct gagtctatta ttaaaaaaga tttatttgag
    29881 ttgacaaaag atgatcttac tggatttgat gctgttattt cagcgtttgg tgcttataca
    29941 ccagatacgc taccgctcca cagcaaatca atcgaactat ttaatcagct tcttgctgga
    30001 acacagacac gttttctagt tgtaggggga gcaggaagtc tttatataga tgaaacaaaa
    30061 acgacacgac ttttagatac gtctgatttt cctgaagaat ttaagtcact agcaaaagct
    30121 caagcggatg aattggatct tcttcgtaca aaaaataatc tcaactggac ttttgtcagt
    30181 cctgctgtag attttattcc cgatggtgaa aaaacaggaa actacattct agcaggagaa
    30241 atttttacta ctaatgaaaa aggaataagc cagattagtt atgcagatta tgctattgga
    30301 ttggtagatg aacttgaaaa aggtcatcat ataaaagaac gtatctcttt acttgaaaaa
    30361 taataactat gagagtatta atgtttgaca gaaaatttaa atcttggtaa aatagggatt
    30421 gtcgtaaaga caaataactt cttcttggtt acaggcatgc caacctgtca ctcggatgaa
    30481 gccaaataaa aaggagaaac atcatggcaa tctcaaaaga gaaaaaaaat gaaatcattg
    30541 cacaatatgc acgtcacgaa ggtgatacag gttcagtaga ggttcaagtt gctgtcctta
    30601 cttgggaaat caaccacctt aacgaacaca tcaaacaaca caaaaaagac cacgctactt
    30661 accgtggatt gatgaaaaaa atcggtcgcc gtcgtaactt gcttgcatac ttgcgtaaaa
    30721 acgacgttaa ccgttaccgt gagttgatca actctctagg acttcgtcgc taattcaaga
    30781 tacaaaggcc gtcaaaaaca caaagcaaaa ataggaaaat tgacgaagaa acttcagttt
    30841 ctaggagatt ttatcttttt tgccaagtgc ttaggccgtg ttcaattgag catatcttga
    30901 taataaagct actctaaatt gggtagcttt gttgcgttgt caccttacct cgctatactc
    30961 aagtataatc ttcggttacg gttcctagca ctgtaaggta aaataaacta gcttttctcc
    31021 cttcggggag atttttttgt ttcactgaaa gtttcgtacg atcttcacct cgtcccctag
    31081 tctataaacg atttatctag caagaatcat gatgctaagg gcgtcaaaaa tccgtatgaa
    31141 aatagggaaa tgacacagtg ttcgatgagc acaaggagtt tcatcttttt cactaggatt
    31201 ttagcccggg ctaaaatcag ctctctgact tcagagggct tttttattga ggttttatcg
    31261 gtaacaattt tggagactac aaaaacctca aatggtatca gctaattaca ccataaaggt
    31321 gcgcagttac tcggcttttc aagccgagta gctgtatgca agccccctag aagagcccac
    31381 tctttacaaa gtaaagtata gtatgttata ctttacatgg aagtagtcac tgaattccag
    31441 ttagaaatta ctttgtaact acgttttgag gaggagtaaa atgctttcct acgttcgaca
    31501 ttacccacta gcgatagcta aattaatgtg tctgtgctct cctaaaatct gctgatttat
    31561 tactgactaa tacaggaggt tttttttatg ggacagacaa tcatatctgc tattggtgtt
    31621 tatatttcca ccagtatcga ttatttaatt attttaatta ttttatttgc acagctatca
    31681 cagaataaac agaaatggca tatttatgcg gggcaatatc taggcacagg cttacttgta
    31741 ggggcgagtt tagttgctgc ttatgtcgtt aatttcgtgc ctgaagaatg gatggttgga
    31801 ttgcttggtt taatccctat ctatttaggg attcgctttg caattgttgg agaagatgcg
    31861 gaagaagaag aggaagaaat tattgaaaga ttagaacaaa gcaaggcaaa tcaactgttt
    31921 tggacagtta cattgctgac aattgcgtct ggcggagata atttaggtat ctatatacct
    31981 tattttgctt cgttagattg gtcacagacc ctcgtggcct tgcttgtgtt tgtaatcggc
    32041 ataattatct tttgcgagat tagtcgggtg ttatcctcta ttccgttaat attcgagaca
    32101 attgaaaaat acgagcgaat cattgtgccc ttagtattca ttctacttgg actatacatc
    32161 atgtatgaaa atggcacgat agagactttt ctgatcgtgt agattttttt gtttcactag
    32221 gattttagcc cgagctcaaa tcagctctct gattttcagg gggctttttc attgagtata
    32281 aatggacaat cttaaagtta ctctattgta gagtggcttt tgatttgatt aggagattct
    32341 tataaatata gtaaaatgaa ataagaatag gacaaatcga tcaggacagt caaatcgatt
    32401 tctaaaaatg ttttagaagt agaggtgtac tattctagtt ccaatctact atataaatga
    32461 aaaccttagc tgtttggcca aggttcattt cttctatgca agttcttctc ttttcttatc
    32521 tgggttccag atgaagcttg cgataaagct aaagatgatg gttaggatag cgaggataat
    32581 agcaaggatg agggcaggga tgcggataaa ccaccagagt ggatttggtt ttttatcatt
    32641 gtgccattgt ttcgtttctt cgtccagacg ttggaattct gtttgaatac gattggcgac
    32701 tgtttcaatg ccttcatcat tcattttctt gatatctgag atatcgattg gatttccaaa
    32761 gttcatatcg acacgttcac ggctaatcaa gcccttcaaa gtcatgggac cggtgtaggt
    32821 aaccggcatg atacggacct tggccatttt ggcaatcagt gctgcgcccc ccttgacatc
    32881 gtttgagtgg cggctaccac ttggaaacat gatgagagag cggtcacttt ttttgagaac
    32941 gttgatagga tatttgatgg ctgaggcgct gggattttca cggtcgatgg gaaaggcgcc
    33001 acacatacga atccaccaac caaagatacg gttggtaaag agttcttttt ttgccataaa
    33061 gatgaactgt tttggcttgg tcgcaaaggc catataaaca ggatcccacc aggtacggtg
    33121 aggcgcaact aaaatataat tttcatcttg attaggaatt ttatcagtat tatgatagtg
    33181 agcattgcca ttgatggacc ataagagcaa tacaactaat ccacgcaaat aagtataaaa
    33241 catgcgatct ccttcgattg ttttcttgtt attattatac cttatcaaag gagggctggc
    33301 aaacttttcc cttgactaga tacatattta ggatgaaatt agaattctgt taaaaaaaat
    33361 gatataatag aatttatgga taaaaataag attatgggat taacccaaag agaagtcaag
    33421 gaaagacagg ctgagggttt ggtcaatgac tttaccgcat cagccagtac cagcacttgg
    33481 caaatcgtta aacgaaatgt ctttaccctt tttaacgctt tgaactttgc cattgctttg
    33541 gctcttgcct ttgtgcaggc ttggagcaat ctggtcttct ttgctgttat ctgctttaac
    33601 gctttttctg ggattgtgac cgagctacga gccaaacaca tggtggacaa gctcaatctc
    33661 atgaccaagg aaaaggtcaa aaccatccgt gatggtcagg aagttgctct taatcctgaa
    33721 gaattagtgc taggagatgt cattcgtttg tctgcaggag agcagattcc tagtgatgcc
    33781 ttggttttgg aaggctttgc ggaagtcaat gaagccatgt taacgggaga aagtgatttg
    33841 gtgcaaaagg aagttgacgg cttacttttg tcaggaagtt tcctagccag tgggtcagtt
    33901 ttatctcaag ttcaccatgt cggtgcagac aactatgctg ccaaactcat gcttgaggct
    33961 aagaccgtta aacccatcaa ctcccgtatc atgaaatcgc tggacaagtt ggctggtttt
    34021 actgggaaga ttatcattcc ctttggtctg gctctcttgc tggaagcctt gcttttaaaa
    34081 ggcctgcctc tcaagtcatc cgttgtaaac tcgtcgacag ctcttttggg aatgttgcct
    34141 aagggaattg cccttttgac cattacttcg ctcttgactg cagtgattaa gttgggcttg
    34201 aaaaaggtct tggtgcagga gatgtactct gttgagacct tggcgcgcgt ggatatgctc
    34261 tgtctggaca agacgggtac catcacccaa ggaaagatgc aggtggaggc tgttcttccg
    34321 ttgatggaaa cgtatggtga agaggctatt gccagcatct tgactagcta catggcccat
    34381 agtgaggata agaatccaac tgcccaagcc attcgccagc gttttgtggg agatgttgct
    34441 tatcctatga tttccaatct tcccttctcg agcgaccgca agtggggggc tatggagtta
    34501 gaaggcttgg ggacagtttt cttaggggcg cctgagatgt tgctggattc tgaagtccca
    34561 gaagccaggg aggccttgga gagaggatca cgtgtcttgg tcttagctct cagtcaggag
    34621 aaattagacc atcacaaacc acagaaacca tctgatattc aggctctagc cttgctggaa
    34681 atcttggact ccattcgaga gggagcagca gagacgctgg actatctccg ttctcaggag
    34741 gtaggactca agattatctc tggtgacaat ccagttacgg tgtccagcat tgcccagaag
    34801 gctggttttg cggactatca caactatgta gattgctcaa aaatcaccga tgaggaattg
    34861 atggccatgg cggaggagac agctattttc ggacgtgttt cccctcatca aaagaaactc
    34921 atcatccaaa cgttgaaaaa agcgggtcat acaacggcta tgacagggga cggggttaat
    34981 gatatcttgg cccttcgtga ggcggattgt tctatcgtga tggcggaggg ggatccagca
    35041 acccgtcaga ttgccaatct ggttctcttg aactcagact ttaatgatgt tcctgagatt
    35101 ctcttcgagg gtcgtcgcgt ggtcaataac attgcccaca tcgccccgat tttcttgata
    35161 aagaccatct attccttcct gttagcagtc atctgtattg ccagtgcttt actaggtcgg
    35221 tcagagtgga ttttgatttt ccccttcatt ccgatccaga ttaccatgat tgaccagttt
    35281 gtggaaggtt tcccaccatt cgttctgact tttgagcgaa atatcaaacc tgttgagcag
    35341 aatttcctca gaaaatccat gcttcgtgcc ctaccaagcg ctctcatggt cgtctttagc
    35401 gtcctgtttg tgaaaatatt tgggagtagc caaggttggt ctgagttaga aatctcaact
    35461 ctcctctatt atctcttggg gtcaattggt ttcttatccg tatttagagc ctgcatgcca
    35521 tttaccctat ggcgtgtcct cttgattgtt tggtcagtag gaggtttcct agccacagct
    35581 ctcttcccaa gaatccaaaa actgcttgaa atttcaacct taacaggaca aacattacct
    35641 gtttatggtg tcatgatgtt ggtctttacc gtgattttca tcctgaccag tcgctatcaa
    35701 gccagaaaat aaagaaaggc tgcaatctgt ggattgcagt ttttttaggt acaagattgc
    35761 cagtcgaaat gtggtataat aagaggtaat agagttttgg aaagtgagag aagatgattt
    35821 caaagagatt agaattggta gcttcctttg tgtcacaggg ggctatttta ctagatgtgg
    35881 gaagtgacca tgcttatctg cctatcgagt tggttgagag aggccaaatc aaaagcgcta
    35941 ttgcaggtga ggtggtggaa ggtccctatc agtctgcggt taaaaatgtt gaggctcacg
    36001 gcctaaagga gaaaatccaa gtccgtttag ccaatggctt ggcagctttt gaagagactg
    36061 accaagtgtc tgtcattacc attgctggca tgggtggtcg tttgattgct aggattttag
    36121 aagaaggttt ggggaagtta gctaatgtag agcgtttgat cctccagccc aataatcgtg
    36181 aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca gaaagcattt
    36241 tagaagaagc tggaaagttt tatgagattt tggtggtgga agcaggacaa atgaagctat
    36301 cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca gtatttgtcc
    36361 aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc ccagaaaaaa
    36421 atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag gtgctccatg
    36481 ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt ttctatggag
    36541 ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag ggtcatggtt
    36601 gccctcgata ttcgtgaaga gacggtggca gaggctattg aaaagggtgt ggacttgatt
    36661 atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag ccgtccgcaa
    36721 aatcagattt acatcgacct gattaagcat gatatcgcag tttatgtcag ccataccaat
    36781 attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg aatcgaggag
    36841 acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg gaatattcag
    36901 cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct agatagcctt
    36961 cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt agcaatttgt
    37021 ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga tgtctatatc
    37081 actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt gttagcattg
    37141 gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact ccttactcaa
    37201 tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc gaccaatcct
    37261 ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta ttggagcagg
    37321 aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacctag aggtgaccgt
    37381 ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca gtccttggtt
    37441 ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg atttttatgt
    37501 ggatttatta gctgatttag agaaatcagg acaagaaatc gacttttacc agcgttcggg
    37561 agtctttctc ttgaaaaagg atgaatccaa gttggaagaa ctctatcaac tggctctcca
    37621 gcgcagagaa gaatctcccc tgataggcca gttagccatt ctggatcaag catcagctaa
    37681 tgaattattc cctggcttgc agggattcga caacttgctc tatgcttctg gtggagcgag
    37741 agtagatggc caactcttgg taactcgtct gctagaagcc agtcatgtca agttggtcaa
    37801 agaaaaagtg actctgacac tcttatcatc aggctaccag attggcgaag aggtgtttga
    37861 tcaggttatt ttggcaacgg gagcttggtt gggggacatg ttagaacctt taggttatga
    37921 agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc aagacatgga
    37981 agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg caggtgggaa
    38041 attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg tagatgaacc
    38101 cttgctccaa caaatggagg aggcggcctt gcctcattac ccagttttag ctagagtgac
    38161 ttcaagggct gagcgtgtgg gaatccgtgc ctataccagt gatttctctc ccttctttgg
    38221 gcaggtgcca gaattggcag gtgtctatgc agccagtgga ctaggttcat caggcctcac
    38281 aactggtcct atcattggtt accatctagc ccaactgatc caagacaagg agttgacctt
    38341 ggaccctcta aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg aataatactc
    38401 aatgaaaatc aaagaacaaa ctaggtaact agccgcgggt tactcaaagc actgctttga
    38461 ggttgtggat agaactgacg aagtcagctc aaaacactgt tttgaggttg tggatagaac
    38521 tgacgaagtc agtaaccata cccatggcaa ggcgacgttg acgtggtttg aattggattt
    38581 tcgaagagta taagcatttt actgaaattt tatcaggtag tttaggatgg caaatgacat
    38641 tccctgtcaa aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa aaaagatgca
    38701 agaaaagatt ttggtaactg gtggtgccgg ttttattgga acccacactg ttattgaatt
    38761 gatccaagca ggccatcaag ttgttgtggt ggataatctt gtcaatagca atcgtaagag
    38821 tttagaagtt gttgaaagaa tcacaggagt tgagattcct ttctatgagg cagatattcg
    38881 tgacacagct accctcagag atattttcaa gcaggaagaa ccgactggtg tcattcactt
    38941 tgctggtttg aaggctgttg gcgaatcaac acgtatccct cttgcctact atgacaacaa
    39001 tatcgctgga actgtcagcc ttttgaaagc catggaagaa aacaactgta aaaacatcat
    39061 cttcagttct tctgcgacag tttacgggga tccgcacaca gtgcccatct tggaagattt
    39121 cccactttca gtgaccaacc catacggtcg tactaagctc atgctagagg aaattttgac
    39181 tgatatttac aaagcagact cagaatggaa tgttgtcttg cttcgttact ttaacccaat
    39241 cggagcccat gagagtggtg atttgggaga aaatccaaac ggtattccaa acaatctctt
    39301 gccatatgtg actcaagtag ccgttggaaa attagagcaa gtgcaagtgt ttggagacga
    39361 ttacgatacg gaagatggaa caggtgttcg tgactatatc cacgttgtcg atttggctaa
    39421 gggtcacgtt gcagctttga aaaaaatcca aaaaggttca ggactaaacg tttataacct
    39481 tggaactggt aaaggttact cagttcttga aattatccaa aacatggaaa aagcggtggg
    39541 ccgtcctatt ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg cctgctactc
    39601 agacccggca aaagctaaag cagaactcgg ttgggaagca gaactcgaca tcacccaaat
    39661 gtgtgaagac gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag actaagatga
    39721 tgatttcaat catcgtccct tgtttaaacg aagaggaagt acttcctctt ttttatcagg
    39781 ctctggaagc tttacttcca gatttggaaa cagaaatcga gtatgtcttt gtcgatgatg
    39841 gatcaagtga tgggaccttg gaactcttaa aggcctatcg ggagcaaaat ccggcagtcc
    39901 attatatttc tttctctcga aattttggca aagaagcagc cctttatgca ggcttgcaat
    39961 atgcgacagg agatttggtg gtggtgatgg atgcagacct ccaagatcct cctagtatgt
    40021 tgtttgagat gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt gggacacgga
    40081 gaactagtcg ggagggagaa cccttctttc gcagtttctg tgctgttctc ttttatcgcc
    40141 tcatgcaaaa aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt cgtatgatga
    40201 gaaggtctgt agtcgatgcc attttaagct tgaccgagtc caatcgtttt tcaaaggggc
    40261 tcttcgcctg ggtgggtttc aaaacctact atttggacta tccaaatgtc gaaaggcagg
    40321 ctggcaagac cagttggagt tttaggcaac tcttttttta ctccattgaa gggattgtta
    40381 atttttcaga tttccctttg actatagcct ttgtagctgg tctcctatct tgttttcttt
    40441 ctctgctgat gacctttttt gttgtggttc ggaccctcat tttgggcaat ccgacatctg
    40501 gttggacctc tctgatggct gttattctct ttcttggagg cattcaactc ttgaccattg
    40561 ggattctcgg taagtatatc agtaagattt atttagagac taaaaaaaga ccactttatc
    40621 ttatcaaaga aaaaagtgac cttcctgatt ttacagaaaa aataaagtga aaagactata
    40681 attttacatg gaaatgtgct aaactagagg gagtggatta tcgccattga tttaggcttc
    40741 ctggtttcca atcagggcgc gagttgggca atttttaaca gcctctaaga catcctgact
    40801 aggagaaatt tctttttcca gttggtcagg gtcatcgtaa aaacgcacga ttccattatc
    40861 gtggtaatca aataaatcag aataagtttg gcaaagtcca caggcgatac atcgttcagg
    40921 tataagtgtg attttcatgt tcatatttat attgtaataa gaaaagtaaa aaaaaacaag
    40981 gagtaaggta tggcaaaaga accgtggcaa gaagatattt atgatcaaga agaatcaaga
    41041 gcagggcgtc ggcatcgaaa ccacggaggg gctgatagga tggctaatcg tattttgacg
    41101 atcctagcta gtattttctt tgtaattgtg gtggtgatgg tcatcgttct catctatcta
    41161 tcatcggggg ggagtaatcg cacagcagcc ttaaaagact ttcatgattc tgatgcaagt
    41221 gtagtacaaa tctcatcttc aagcagttct cagcctgagc agagttcaga gccagaatct
    41281 acttctagta gttcagaaga agctgctaat cctgaaggaa cgattaaagt tctcgcagga
    41341 gaaggggaag cagctattgc cgctcgtgca ggaatctcca ttgctcagtt agaggccttg
    41401 aatcctgggc acatggctac aggatcttgg tttgctaatc caggtgatgt tataaaaata
    41461 aaataggagc cgatatgaaa acaattcaaa ttgctattga tggtcctgct tccagcggta
    41521 agagtacggt cgcaaagatt attgctaagg attttgggtt cacctacctt gatacaggag
    41581 ctatgtatcg tgcagcgacc tatatggctc ttaagaacca attaggagtt gaagaagtcg
    41641 aagaccttct agccttgttg gaccagcatc caatcagctt tggacgttca gaaactggag
    41701 accagcttgt ttttgtagga gatgtggata ttacccatcc tatccgtgaa aatgaagtga
    41761 ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg gtttctctcc
    41821 aacaagaaat tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt ggaactgttg
    41881 tattgccaca agcagaattg aaaattttcc tagtagcttc tgttgatgag agagcagagc
    41941 gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc ctaaaaaagg
    42001 aaattgctgc gcgtgactac aaggatagtc atcgtgagac ttctcctctc aaacaagcag
    42061 aggatgctgt ctaccttgat acaactggtt tgaacattca agaagtagtt gaaaaaatca
    42121 aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg atagattgat atcggttttt
    42181 ttctaaattt gtcaaaatgc tgattttagg gtataatagt tgctgttcga gaaattttga
    42241 ttttcaaaga atagtgaatg atgataagga gaaaccatga acaatttacc aaattgtcca
    42301 aaatgtaact cagagtatgt ctacgaagac ggtgccctac tggtttgccc agagtgtgct
    42361 catgagtgga atcctgctga agttgcagaa gtagaagaag gtcttgtcgc tatcgatgcc
    42421 aacggaaata aattgactga tggtgataca gtaactctca tcaaggactt gaaagtaaaa
    42481 ggtgcgccaa aagatttgaa acaagggacg cgcgtgaaaa atatccgcat cgtagaaggc
    42541 gatcacaata tcgactgtaa gattgatggt tttggtgcca tgaaacttaa atcagagttt
    42601 gtgaggaaga tttaagcatg tcaaaacact ataaacttgt attttatagc cgtatcttct
    42661 tgtttctagc ggcttttacg ggagtttatc ttgaaattac taggcatggt ggttttggga
    42721 tgcttctcta ttacacggtt ctgtccaacc tcttggtaac tatttttacc ctttatcttc
    42781 taaaggttat gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg cgcttaaaag
    42841 gtggggtcac catgagtatc atgattacct gtgtgattta ccatttcctc ttggcgccca
    42901 ttgcgactaa tttctatacc ctagaaaatt tcctttgcca ctatatcgtt cccatctggt
    42961 ttttagcgga taccctcttt tttgacaaac agggtcaata caagatttgg gatccagcag
    43021 tgtggaccat tttacccttt ctgtatatga tgtttgctct ttttaatggc ttggttctaa
    43081 aactcaatat tccaaatgcc aaggataatc ctttccctta cttctttttg aatgtgaaca
    43141 agggttggaa tgttgtgttt aagtggtgtc tgattatctt tgttgcctat atggtagcag
    43201 gatttatttt ctactttatc aagcaaatca agagaaagtc atcctaatac tcttcgaaaa
    43261 tctcttcaaa ccacgttagt ttccatctgc aacctcaaaa cactgttttg aacaacctgc
    43321 ggctagcttt ctagtttgct ctttgatttt cattgagtat gagatacaag ggattcattt
    43381 tcgaatttaa gaaggagtct acaaaccaat gaggcttctt cttttcttgc ttatttgata
    43441 actatcaaaa aagtagaaga ttaagagaaa tatagaaaga gatttcatga aacaattttt
    43501 agaacgggcc agcattttgg ctctctccct cgttttgatt acctcctttt ccatttcgag
    43561 tgccctacca gccatgtttg actattatca gggttattct aaggaacaaa ttgagctctt
    43621 ggtgagcttg ccttcctttg gaatcatgat gatgttactg ctaaatggtt tcttagaaaa
    43681 aatatttcct gagcgcttac agattagttt gggcttgctg attttatcat tgagcggtac
    43741 agctcccttc tggtaccaag cctatccctt tgtctttgga acacggcttc tctttggttt
    43801 gggtcttggg atgatcaatg ccaaggccat ttctattatc agtgaacgct accaaggaaa
    43861 aaggcgaatt cagatgttag ggctacgcgc ttctgcagag gtcgttggag cttctctcat
    43921 taccttggcc gtcggtcagt tgttggcctt tggttggaca gctatctttc tagcctatag
    43981 tgctggattt ttggtgatgc ccctttatct gctctttgtc ccttatggaa aatcaaagaa
    44041 agaagtcaag aaaagagcga aggaagcaag tcgtttaact cgagaaatga aaggcttgat
    44101 ttttacctta gctatcgaag cggcagttgt agtttgtacc aatacagcta ttaccatccg
    44161 tattccaagt ttgatggtgg aaagaggatt gggggatgcc cagttatcta gttttgttct
    44221 tagtatcatg cagttgatcg ggattgtggc tggggtgagt ttttctttct tgatttctat
    44281 ctttaaagag aaactgctcc tctggtctgg tattaccttt ggcttggggc aaatcgtgat
    44341 tgccttgtct tcatccttgt gggtggtagt agcaggaagt gttctggctg gatttgccta
    44401 tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa cgaattccag ctaaactcct
    44461 caatcaagca acttcatttg ctgtattagg ctgtagtttc ggagccttta cgaccccatt
    44521 tgttctaggt gcaattggct tactaactca caatgggatg ttggtcttta gtatcttagg
    44581 aggttggttg attgtaatct ctatctttgt catgtaccta cttcagaaga gagcttagga
    44641 ttgattccta agtttttctt ttgatactca atgaaaatca aagagcatag ttgattgagt
    44701 ttggaatagt acgctgtagc tgctaaaata tttctagaaa ttaatttgac ttttctaata
    44761 gagttattca tatcttattt caatctacta tagaaagcta gccgcaggtt gctcaaaata
    44821 gtgttttgag gttgcagatg gaaactgacg tggtttgaag agattttcga agagtatgag
    44881 atttttatac ccatacaata tttgttttag gtccttgttt acagactaat ttcttgataa
    44941 aatagaggtt atgacgagat ataaagcaac tatttcctat gatggttatg cctttgctgg
    45001 ctttcagcgc cagtctcatg cgcgtagcgt tcaggaagaa attgaaaaaa ccttgaccag
    45061 attaaataaa gggcaaacca ttactgttca cggtgctggt aggacagata gtggggttca
    45121 tgccctggga caggtcattc attttgacct gccttatcag atggatgagg agaaactccg
    45181 ttttgccttg gatacccagt ctcctgaaga tattgatgtg atttcgattg agcttgtggc
    45241 agatgatttt cattgccgtt atgccaaaca tagcaagacc tatgagttta ttgtggatag
    45301 aggacgtccc aaaaatccta tgcgccgtca ctatgccacc cactttccct acccactcga
    45361 tgtggaacga atgcagattg caatcaaaaa gctagaggga acccatgatt ttaccggttt
    45421 tacagcctct gggactagtg tagaggataa ggttcgcacc atcacagaag ctagtttaat
    45481 agtcgatgag acaggacaat ttttgacctt taccttttca ggaaatggtt tcttgtataa
    45541 acagattcgc aatatggtgg ggactcttct caaaatcggt aacaaccgca tgccagtaga
    45601 gcagattgat ctcatcttgg agaagaagga caggcaactt gcaggtccca ctgcagcacc
    45661 aaatggtttg tatttaaagg agattcgtta tgaagaataa tcgtatttta gcactttctg
    45721 gaaatgatat ttttagtggt ggtggactgt cagctgattt ggctacctat accttgaacg
    45781 gcttgcatgg gtttgtagca gtgacttgtt tgacagcctt gacagaaaaa ggatttgaag
    45841 tctttccaac tgatgatacc atttttcaac atgaattaga tagcttacgt gatgtggaat
    45901 ttgggggaat taagattggt cttctcccta ctgtcagtgt ggctgagaag gccttggact
    45961 ttatcaaaca acgcccagga gtacctgtgg tgttggatcc tgtcttggtc tgcaaggaaa
    46021 cgcatgatgt agctgtcagt gagctctgcc aagagttgat tcgctttttc ccttatgtca
    46081 gtgtgattac gcctaatctc ccagaagcag aattattatc cggtcaggaa attaaaacct
    46141 tggaagacat gaaaactgca gcgcagaaat tgcatgattt aggagcgcca gcagtcatta
    46201 tcaagggagg caatcgtctt agtcaggaca aggctgtgga tgtcttttat gatggacaga
    46261 cctttactat cctagaaaat ccagttatcc aaggccaaaa tgctggtgca ggttgtacct
    46321 ttgcctctag cattgccagt cacttgatta aaggtgataa acttttgcca gcagtagaaa
    46381 gctctaaggc tttcgtttat cgtgctattg cacaagcaga tcagtatgga gtaagacaat
    46441 atgaagcaaa caaaaacaac taaaatcgcc cttgtatccc tattaaccgc cctttctgtg
    46501 gttctaggtt atttcttaaa aatcccaaca cctacaggaa ttctaactct tttagatgct
    46561 ggtgtcttct ttgcggcctt ttactttggt agtcgtgaag gagcggtagt cggaggacta
    46621 gcaagtttct tgattgacct cttatcaggc taccctcagt ggatgttctt tagcttggtc
    46681 aaccatggct tgcagggatt tttcgcagga tttaaaggaa aaagtcagtg gttaggcctt
    46741 attttagcaa ctattgccat ggtaggaggc tacgccttgg gttctacttt gatgaatggc
    46801 tgggcagcag ccctcccaga aattctacca aatttcatgc aaaatatggt agggatgatt
    46861 gtaggattta ttcttagtca aagtatcaag aagattaagt aatactcttc gaaaatctct
    46921 tcaaaccacg tcagcttcca tctgcaacct caaaacactg ttttgagcag cctgaggcta
    46981 gctttctagt ttgcactttg attttcattg agtataaaga ggttgagtaa aaagtatttc
    47041 aaataagaaa aacgcatagt atcaggtgtt gaatgaactg ccccccaaaa gttagacaga
    47101 aaaaatctaa cttttggggt gttttattat gaaactaact tatgatgata aagttcagat
    47161 ctatgaactt agaaaacaag gatatagctt agagaagctt tcaaataaat ttgggataaa
    47221 caattctaat cttaggtaca tgattaaatt gattgatcgt tacggaatag agttcgtcaa
    47281 aaaagggaaa aatcgttact attctcctga tttaaaacaa gaaatgattc ataaagtctg
    47341 acatgaaggc tagactaaag atagagtttc tcttgaatac ggtctcccaa gtcgtac
//
LOCUS       DBEJJV010000012        47341 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.012, whole genome shotgun sequence.
ACCESSION   DBEJJV010000012 DBEJJV010000000
VERSION     DBEJJV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 47341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.012"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..653)
                     /locus_tag="ACL3GT_000774"
     CDS             complement(<1..653)
                     /locus_tag="ACL3GT_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516467.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNVLLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYM"
     gene            complement(646..1374)
                     /locus_tag="ACL3GT_000775"
     CDS             complement(646..1374)
                     /locus_tag="ACL3GT_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516468.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSENILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(1408..1578)
                     /locus_tag="ACL3GT_000776"
     CDS             complement(1408..1578)
                     /locus_tag="ACL3GT_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516469.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYAISLGLLNGIV
                     LGSLIFYKNNKN"
     gene            complement(1591..3717)
                     /locus_tag="ACL3GT_000777"
     CDS             complement(1591..3717)
                     /locus_tag="ACL3GT_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGR0516470.1"
                     /translation="MMTRKVPNIEQMSQIECGLCCCLSILHFYKSKETLLDLRRDIEK
                     GRDGYSIGDLKQLLNKRNFDTGSYQVKDVNKISELPLPLITFWDNQHYVVIYKVKKNK
                     VYIMDPSKGYINYEFKEFSKHFSNIVLLSFPNENYQSLKSQFPSPWIRVFSSFSKVKG
                     RLILTLLFSIISYLIILSVPVMTSKFINSALGNTFSFQTSFLILFSLLCLYLISILAR
                     SMGILFSNIFFSRDIESFTFKHLLKLPYSFFELRAKGDILYRISSLSGFRELFTNQVV
                     GGVVDIGTILSVVIYMFLSSKTLSIIALILSLINFLFLFSTRKIMYDTVNRELQEQSL
                     IYSVETEALNTISSIKISGLEDEIYENWSKYLKNVLTKYKKRSIVHILYNSATNVFQL
                     FAPIIILIFGLDNVLNGKILLGEVVAFQTMASILFSSEISIFNAYTQYILAAGYLNRV
                     NDIWLENEENVENGLKKCSLEGRIDIKDLSFSYSKDSAPVIENLNLTIEPGQRIALVG
                     QSGSGKSTLSKILSGLYKIDTGKILFDGVNINQIDKKILSQNLGVVPQDSFLLNRSIL
                     DNITLKNEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIALARA
                     LINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIIAHRLSTIKDADIIFVMKGG
                     KIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            complement(3707..4255)
                     /locus_tag="ACL3GT_000778"
     CDS             complement(3707..4255)
                     /locus_tag="ACL3GT_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0516471.1"
                     /translation="MSLSYYYEINPSTDILKCIEELLYKEDKCFNNILKNWKDIRRNH
                     NDSFPNFWCYGAPGILLARKEIFDKTNIGNNDLSIIKNVLTNVEKIRELNLCHGSVGT
                     ISCLDAILKDEENLLIKESIDFYFDNVVSQVIKPELSTDLNTMNTFSFMLGVSGVVYE
                     ISRKQDDRLLNVLLLELRGHDD"
     gene            complement(4336..4398)
                     /locus_tag="ACL3GT_000779"
     CDS             complement(4336..4398)
                     /locus_tag="ACL3GT_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HGR0516472.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            4478..5332
                     /locus_tag="ACL3GT_000780"
     CDS             4478..5332
                     /locus_tag="ACL3GT_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0516473.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLVLHNDDYTSSESFANLVQYIRKQYSSQSINNIACLLSDT
                     SDYTLNSFEKTMVKSILHTMDSNIIPSDEELLHLTDYLFKIEKWGYYEIILLGNCVRT
                     INYNSYFLLTKEMLNNYIYSSLNKTNKQIVSQLAINCFILSIDKEEFSNCSYLISKIK
                     TLLDNELNFYEQTVFLYATGYFEFKRCQSTSGIEKMKQAIQVFDILGENKLKLHYTDH
                     FNKLVNKK"
     gene            complement(5377..7262)
                     /locus_tag="ACL3GT_000781"
                     /pseudo
     CDS             complement(5377..7262)
                     /locus_tag="ACL3GT_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775543.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1250 family conjugative relaxase"
     gene            complement(7285..7614)
                     /gene="mobC"
                     /locus_tag="ACL3GT_000782"
     CDS             complement(7285..7614)
                     /gene="mobC"
                     /locus_tag="ACL3GT_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HGR0516474.1"
                     /translation="MVYRYRTNLKKVFLTDPELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSHLISQDQLQELSKGVGELIKE
                     VDKEFQV"
     gene            complement(7624..7983)
                     /locus_tag="ACL3GT_000783"
     CDS             complement(7624..7983)
                     /locus_tag="ACL3GT_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1252 family conjugative relaxosome accessory
                     protein"
                     /protein_id="HGR0516475.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            complement(8815..9192)
                     /locus_tag="ACL3GT_000784"
     CDS             complement(8815..9192)
                     /locus_tag="ACL3GT_000784"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516476.1"
                     /translation="MGQKVVAMLDFLLAYSDYSKDFRPLIIDQPEDNLDNRYIYRHLV
                     QQFRDVKAQRQIILATHNATIVTNSMTDQVVIMESDGVNGWIESQGYVSEKYIKNHII
                     NQLEGGKDSFKHKMSIYETALSE"
     gene            complement(9195..9971)
                     /locus_tag="ACL3GT_000785"
     CDS             complement(9195..9971)
                     /locus_tag="ACL3GT_000785"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516477.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISEKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFWSLILTRKNFRNNLIFSIKKLVY"
     gene            complement(9999..10760)
                     /gene="pezT"
                     /locus_tag="ACL3GT_000786"
     CDS             complement(9999..10760)
                     /gene="pezT"
                     /locus_tag="ACL3GT_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin PezT"
                     /protein_id="HGR0516478.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLGYNLLIEGTLRTIDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRKLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELFFGEWSQVEKEMLQVGEKRLNELLEK"
     gene            complement(10760..11236)
                     /gene="pezA"
                     /locus_tag="ACL3GT_000787"
     CDS             complement(10760..11236)
                     /gene="pezA"
                     /locus_tag="ACL3GT_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PezA"
                     /protein_id="HGR0516479.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIHTNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            complement(11681..12136)
                     /locus_tag="ACL3GT_000788"
                     /pseudo
     CDS             complement(11681..12136)
                     /locus_tag="ACL3GT_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12411..14150)
                     /locus_tag="ACL3GT_000789"
     CDS             complement(12411..14150)
                     /locus_tag="ACL3GT_000789"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HGR0516480.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESASNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEINSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELD
                     NQLVISPDGFMIF"
     gene            complement(14313..15197)
                     /locus_tag="ACL3GT_000790"
     CDS             complement(14313..15197)
                     /locus_tag="ACL3GT_000790"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0516481.1"
                     /translation="MKKAMVIITPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEAIHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKLKED"
     gene            complement(15309..16163)
                     /locus_tag="ACL3GT_000791"
     CDS             complement(15309..16163)
                     /locus_tag="ACL3GT_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HGR0516482.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(16221..16979)
                     /locus_tag="ACL3GT_000792"
     CDS             complement(16221..16979)
                     /locus_tag="ACL3GT_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0516483.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(17041..17229)
                     /locus_tag="ACL3GT_000793"
     CDS             complement(17041..17229)
                     /locus_tag="ACL3GT_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HGR0516484.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(17551..18117)
                     /locus_tag="ACL3GT_000794"
     CDS             complement(17551..18117)
                     /locus_tag="ACL3GT_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516485.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(18385..20064)
                     /locus_tag="ACL3GT_000795"
                     /pseudo
     CDS             complement(18385..20064)
                     /locus_tag="ACL3GT_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(20156..20317)
                     /locus_tag="ACL3GT_000796"
     CDS             complement(20156..20317)
                     /locus_tag="ACL3GT_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516486.1"
                     /translation="MNNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(21001..21300)
                     /locus_tag="ACL3GT_000797"
                     /pseudo
     CDS             complement(21001..21300)
                     /locus_tag="ACL3GT_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(21281..21670)
                     /locus_tag="ACL3GT_000798"
     CDS             complement(21281..21670)
                     /locus_tag="ACL3GT_000798"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0516487.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(21723..21907)
                     /locus_tag="ACL3GT_000799"
                     /pseudo
     CDS             complement(21723..21907)
                     /locus_tag="ACL3GT_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612340.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(22058..22852)
                     /locus_tag="ACL3GT_000800"
     CDS             complement(22058..22852)
                     /locus_tag="ACL3GT_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516488.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            complement(22852..23859)
                     /locus_tag="ACL3GT_000801"
     CDS             complement(22852..23859)
                     /locus_tag="ACL3GT_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HGR0516489.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(23859..24866)
                     /locus_tag="ACL3GT_000802"
     CDS             complement(23859..24866)
                     /locus_tag="ACL3GT_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HGR0516490.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(24856..25881)
                     /locus_tag="ACL3GT_000803"
     CDS             complement(24856..25881)
                     /locus_tag="ACL3GT_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HGR0516491.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(26274..26492)
                     /locus_tag="ACL3GT_000804"
     CDS             complement(26274..26492)
                     /locus_tag="ACL3GT_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0516492.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(26738..27016)
                     /locus_tag="ACL3GT_000805"
     CDS             complement(26738..27016)
                     /locus_tag="ACL3GT_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516493.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(27230..28861)
                     /gene="rlmD"
                     /locus_tag="ACL3GT_000806"
     CDS             complement(27230..28861)
                     /gene="rlmD"
                     /locus_tag="ACL3GT_000806"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0516494.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLDMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(28935..29909)
                     /locus_tag="ACL3GT_000807"
     CDS             complement(28935..29909)
                     /locus_tag="ACL3GT_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HGR0516495.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(29983..30597)
                     /gene="pmp23"
                     /locus_tag="ACL3GT_000808"
     CDS             complement(29983..30597)
                     /gene="pmp23"
                     /locus_tag="ACL3GT_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HGR0516496.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVQLNLYIIKCFTLFSTSG"
     gene            complement(30597..31571)
                     /locus_tag="ACL3GT_000809"
     CDS             complement(30597..31571)
                     /locus_tag="ACL3GT_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HGR0516497.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(31579..32835)
                     /gene="glyA"
                     /locus_tag="ACL3GT_000810"
     CDS             complement(31579..32835)
                     /gene="glyA"
                     /locus_tag="ACL3GT_000810"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HGR0516498.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFLLYED"
     gene            complement(32897..33328)
                     /locus_tag="ACL3GT_000811"
     CDS             complement(32897..33328)
                     /locus_tag="ACL3GT_000811"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0516499.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEEEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(33330..33932)
                     /locus_tag="ACL3GT_000812"
     CDS             complement(33330..33932)
                     /locus_tag="ACL3GT_000812"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HGR0516500.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(33916..34755)
                     /gene="prmC"
                     /locus_tag="ACL3GT_000813"
     CDS             complement(33916..34755)
                     /gene="prmC"
                     /locus_tag="ACL3GT_000813"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HGR0516501.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(34755..35834)
                     /gene="prfA"
                     /locus_tag="ACL3GT_000814"
     CDS             complement(34755..35834)
                     /gene="prfA"
                     /locus_tag="ACL3GT_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HGR0516502.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(35831..36421)
                     /locus_tag="ACL3GT_000815"
     CDS             complement(35831..36421)
                     /locus_tag="ACL3GT_000815"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HGR0516503.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            36544..36726
                     /locus_tag="ACL3GT_000816"
     CDS             36544..36726
                     /locus_tag="ACL3GT_000816"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HGR0516504.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            36862..38235
                     /gene="mnmE"
                     /locus_tag="ACL3GT_000817"
     CDS             36862..38235
                     /gene="mnmE"
                     /locus_tag="ACL3GT_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HGR0516505.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIVQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEQLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(38282..39217)
                     /gene="dapA"
                     /locus_tag="ACL3GT_000818"
     CDS             complement(38282..39217)
                     /gene="dapA"
                     /locus_tag="ACL3GT_000818"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HGR0516506.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(39273..40349)
                     /locus_tag="ACL3GT_000819"
     CDS             complement(39273..40349)
                     /locus_tag="ACL3GT_000819"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HGR0516507.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(40980..41052)
                     /locus_tag="ACL3GT_000820"
     tRNA            complement(40980..41052)
                     /locus_tag="ACL3GT_000820"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(41017..41019),aa:Thr,seq:ggt)
     gene            complement(41152..41661)
                     /locus_tag="ACL3GT_000821"
     CDS             complement(41152..41661)
                     /locus_tag="ACL3GT_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HGR0516508.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(41659..41755)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            41784..42215
                     /locus_tag="ACL3GT_000822"
     CDS             41784..42215
                     /locus_tag="ACL3GT_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HGR0516509.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            42297..42674
                     /gene="mscL"
                     /locus_tag="ACL3GT_000823"
     CDS             42297..42674
                     /gene="mscL"
                     /locus_tag="ACL3GT_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HGR0516510.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(42716..43810)
                     /gene="hemH"
                     /locus_tag="ACL3GT_000824"
     CDS             complement(42716..43810)
                     /gene="hemH"
                     /locus_tag="ACL3GT_000824"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004325 - ferrochelatase activity
                     [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HGR0516511.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            43965..45188
                     /gene="pepT"
                     /locus_tag="ACL3GT_000825"
     CDS             43965..45188
                     /gene="pepT"
                     /locus_tag="ACL3GT_000825"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HGR0516512.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKEQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(45224..45877)
                     /locus_tag="ACL3GT_000826"
                     /pseudo
     CDS             complement(45224..45877)
                     /locus_tag="ACL3GT_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672614.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family hydrolase"
     gene            45875..46039
                     /locus_tag="ACL3GT_000827"
                     /pseudo
     CDS             45875..46039
                     /locus_tag="ACL3GT_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(46310..47321)
                     /locus_tag="ACL3GT_000828"
                     /pseudo
     CDS             complement(46310..47321)
                     /locus_tag="ACL3GT_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1,RefSeq:WP_007521835.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT        14317 a         9361 c         7456 g        16207 t
ORIGIN      
        1 atcatataaa attgactttc agtcactcta aaagcatgag aaagataagt aaatggtaag
       61 taaatcttaa aattataatc gttgtagtat atgctaattg ttaaaatcat cattataata
      121 ccaattggta ttattccaga aattttcctt ataagtacta aagttagaaa atataataac
      181 attatcatca acgaggaaat taattgaatg gtaaatgttt ttaaaaagaa aatcaaacca
      241 atctctaaac tgttatcaat agccttccca ataacgtata agctaatata atcagacaac
      301 caaaaagtaa atgtgtaaac cactgtaatg agtaatttag aatttattgt gtacttgttt
      361 ctaaatggca atgaaattac ggttaaccat gcatcatttt taaattctac tgcaaacact
      421 tcgtaaatta ttaaagatag aactaaataa aatagttcag aaaaataaaa tattgtttgt
      481 tctttaaaaa ttaactgcca attagataaa gcaagttcat tttgatgcac caataaataa
      541 cctcgatacc taaaagttaa gtctatatat aacaaaacat tcagaattat tggaaaaata
      601 agaacaaacc ataagatgct ttttttctgc tttagaaact ctaatttaat catattcacc
      661 tccagctaaa caagctaagt aggcttcttc cagatttcga caattatact tttgtaaaag
      721 gtagtggcaa gaaccaaaaa attcaacttt cccataattt ataattataa tatcagatat
      781 cactttatcc agttcactaa gaatatgact tgatattaaa aatgtaatac cttttttctc
      841 ctgtagaaaa cggattaaac ttctaatttc aattacaccc tgtggatcaa gtccattgat
      901 tggttcatcc caaattaata tttctggact acctaacaat gatgcagcta tacttagacg
      961 ttgtttcatg cccattgaaa aatttttcac ttttttcttt ttaacatctt ttaatcctac
     1021 cattgataga tattcattaa gtctttcagt atctaaacta agccctttca tatttgctat
     1081 taacttcaaa tttttataag catcaagatg accataaaat gaaggtccca aaactaatcc
     1141 tatcctagat aatatatttt cggaattctg ttctacggtt tgattaaaaa tagttatttt
     1201 cccagaatct ggttttaaaa tccctagaat cattttgata attgtagttt ttccagcccc
     1261 atttggtcca acaaaaccat atacttttcc cttatttaaa taaaatgaag tgttatgaat
     1321 aacttcaata tctttaaagc tttttgttag atttataatt tcaactatag ccatctctac
     1381 tccttagttt acagcaaaaa attatgctta attcttattg tttttgtaaa aaatcagcga
     1441 acccaatact attccattca acaaacctaa agaaatagca tattcaactg gaaaatctaa
     1501 aaaaattgca aatactattc caatcatcac ccctagtgag gctgctgttg aaattacata
     1561 ttcatttact ttcttcattt tctttacacc tcatttcctt tttgtatata agctgtagta
     1621 ctctccacca agatccatta agtacttatg atttcctgac tcaacaatct taccaccttt
     1681 cattacaaaa ataatatccg catccttaat cgttgacaat ctatgagcta taattatttg
     1741 agtacaaccc tgactttgta tatactttgt tattctttcc tcattaatag tgtctaatgc
     1801 actagttgct tcatctaaaa ttacaatact aggattattt attaatgcac gtgccagtgc
     1861 tatccgttgc ctttgcccac ctgaaatatt tgaccccatc tctgagatga tagtattaaa
     1921 tttcatcggc atagccatga tttcatcata gatttgaact gctttacaaa cttcctctat
     1981 cttttgtgaa gtaacttcgt tctttaaagt tatattatca agaatacttc ggttcaataa
     2041 aaatgaatcc tgtggaacta ctcctaaatt ttgacttaat atttttttat ctatttgatt
     2101 aatatttaca ccatcaaata aaatttttcc tgtatcaatc ttatataatc ctgatagtat
     2161 ttttgataac gtactttttc ctgaccccga ttgaccgact agtgcaattc tctgtcctgg
     2221 ctcaatagtc aaatttaaat tttctattac aggagctgag tctttggaat aagagaaaga
     2281 taggtcctta atatctattc taccttctaa agaacacttt ttaagaccat tttcaacatt
     2341 ctcttcattt tcaagccaga tatcatttac tctatttaag tatcctgctg ccaaaatata
     2401 ctgcgtataa gcattaaata ttgagatttc tgaactaaat aaaattgatg ccatggtttg
     2461 aaatgcgaca acctcaccca ataaaatttt tccatttaaa acattatcaa gtccaaaaat
     2521 caatataatt ataggagcga acaattgaaa tacattagta gctgaattgt ataaaatatg
     2581 cacaatactt cgttttttat actttgtcaa tacgtttttt aaatacttag accagttttc
     2641 atatatttca tcttctaatc ccgatatttt tattgaagaa atagtattta atgcttctgt
     2701 ttctactgag taaatcaatg attgttcttg taattctcta ttaaccgtat catacattat
     2761 ttttctagta ctaaacagaa acaaaaaatt gattaaactc aatataagag ctataattga
     2821 taatgttttt gaactaagaa acatatatat tacaacactt agaatagtcc cgatatctac
     2881 tactccccca acaacttggt tagtaaatag ctccctaaaa ccactaagac tagaaattct
     2941 gtataaaata tctccttttg ccctgagttc aaaaaaacta tatggtagtt taagcaaatg
     3001 cttaaatgta aaactttcaa tatctctact aaaaaatata ttagaaaata gaattcccat
     3061 actcctagcc aagatagaaa taagatacaa acaaagtaga gaaaataaaa ttaaaaacga
     3121 ggtttgaaaa gaaaatgtat tccctaatgc agaattaata aactttgaag tcattactgg
     3181 tacggaaagt attattaagt aacttattat tgaaaatagt aacgtcaaaa tcaatcgacc
     3241 ttttaccttt gaaaaactag agaatactct tatccatgga gaaggaaact gcgacttcaa
     3301 agattgataa ttttcgttag gaaatgatag cagtactata ttactaaaat gttttgaaaa
     3361 ctccttaaac tcataattta tatatccttt agaaggatcc attatataga ccttattctt
     3421 ttttactttg taaataacta cataatgttg attatcccag aatgttatta atggtaacgg
     3481 aagttcacta attttattta catctttaac ttgatatgag ccagtatcaa aatttcgttt
     3541 attcaataac tgtttcaagt cacctatact ataaccatct ctcccttttt ctatatcacg
     3601 tcttaaatct agtaatgtct ctttgctttt atagaaatgt agtatggaca agcagcaaca
     3661 taaaccacat tctatttgag acatttgctc aatattaggt acttttctag tcatcatgtc
     3721 ctcttaactc cagtaataaa acattaagta atctatcatc ttgttttcga gatatttcat
     3781 agacaactcc agatactcct agcataaaag aaaatgtatt catagtattc aaatccgtac
     3841 ttaattctgg tttgatgacc tgagaaacga cattatcaaa ataaaaatct atagattctt
     3901 ttattaatag gttttcttca tctttcaata ttgcatcaag acaactgata gtacctacag
     3961 aaccgtgaca taaattcaat tctcttattt tttctacatt agttaataca tttttaatta
     4021 ttgataaatc attattccca atattagttt tatcgaaaat ttcttttcta gctaataaaa
     4081 tgcccggagc tccataacac caaaaattag gaaaggaatc attatgattt cttcttatgt
     4141 ctttccaatt ttttaatata ttattgaaac atttatcttc tttatatagt aattcctcta
     4201 tacattttaa tatatctgta ctaggattaa tttcataata atatgataat gacattgcta
     4261 ctccagaata accgtgtgct aaacctgtta ctgttatatt atctaattgt gaaatacaat
     4321 aattaataca cttttttaaa tgatgataat atccatcacc aaaaccaaaa tcggtaaaaa
     4381 ttttgaaatt ttcttcatac ttggacttcc tttccgtttt tatttattgt acaataaata
     4441 aaaacggatt taatttttgt tgggaaaatg ggaaattatg aaatcaaaac ttggcatcac
     4501 acttagaaaa gttcgtaaag gaaaacaaat tagtctatgc tctgtagcag atgaacatct
     4561 ttcaaaatca caaatatctc gttttgaacg tggggagtca gagatatctt gtattcgact
     4621 aatcaatatt ttagacaaat tacatattac tttggatgag ttccttgttt tacacaatga
     4681 cgactatacc agttccgaat catttgctaa tctagtacag tacattcgta agcaatattc
     4741 atcacaaagt atcaataata tagcatgtct actttctgat acttctgatt acactctaaa
     4801 ttcttttgag aaaacaatgg taaaatctat tttacacaca atggattcga acatcattcc
     4861 atcagatgaa gagcttcttc atctgacaga ctatcttttc aaaattgaaa aatggggcta
     4921 ttatgaaatc attttattag gtaactgtgt acgcacaatt aactacaact cctacttctt
     4981 attaactaaa gagatgttaa ataactatat ttactcatct ctgaataaaa ctaataagca
     5041 gattgtctct cagcttgcta ttaattgctt cattctaagc attgataagg aagaattttc
     5101 taattgctcc tatttaatta gtaagataaa gacattgttg gataatgaac taaactttta
     5161 tgaacaaaca gtttttctct atgcaactgg ttactttgaa tttaaacgtt gccaatcaac
     5221 cagtggaatt gaaaaaatga aacaagccat acaagtcttc gatattttag gagaaaataa
     5281 gttaaaatta cactatactg accattttaa taaactagta aacaaaaaat aaatgaaatt
     5341 attctctatc ttttaactaa ttagtcgtaa ataatattat tctagtaagg cattctcgtg
     5401 aaattttaga actgtaaatt tattggtatt aataattttc acaaacaaat ccaatcttct
     5461 agctatctcc tcatatttat taatttcatt actaagttcc tgttgtaatt ttaaaatata
     5521 tgtattgagt cgatctaaca ttattgattc cgtcatgttc atttggtcaa aatcatactt
     5581 agctaatttt ctaccgatct catcttcact cttcaaattg ataaggactt ccgccatctt
     5641 gtttaaggtg gcgatttttt cttgggtttc ttctagcttc atatcaatct ctgcaatttc
     5701 taatacaagc tcatctttga tttcttggta ttgtttgttc gtgttagata gttcaatcat
     5761 aagattaatt tcagaaatct tctcttgaag actttttaaa gttggtcgtc tataggggag
     5821 tttttggcta tcgttgctca attgtctgat taaggtccta cccttgatga aacaattatt
     5881 atccatgttt tctttattat agacaaagta agaagacgtt tctcgaatgt agactttata
     5941 ttttttatga ttttcttctt ccataatatc caattgatag ttgggaatga aaataagacc
     6001 gctctatttg acaccgaaag acaccttgat atagacgccc ttatcaacta gcttctctat
     6061 ttggttctct gcaagttcca cttcaaattc acgaacggta tctcattttt ccttaaatgt
     6121 cttaaaggct tcttaaatgt cttaaaggct tcctcaatct cttcagtgga tactttatcc
     6181 ttatctcgtt cttcttggaa agcatggtac tgttcctgta aattctctaa tccttctgaa
     6241 gcaatgactt ccttattttt aaaataatct tgaaaaaatt tgacatcata taatttctta
     6301 tcacttattt tttgatgacc caaacttatc ttttgattat tttctttcag gataaaagtt
     6361 acattttttt gttttaagtc aatggttaga ttcaattctt ttgcttttgt tattaactct
     6421 tctaaagaat tgacacggtt caacaaaaat tctaaacgac tttcaatctc ttgcttagca
     6481 aaatgcgttc taaaaaattc ttcatcatat agatctcgtt tgctgagttg gcgtcctcga
     6541 ataggttttg tcattgctcg atccgtcatc atgaatcgac tatgcttttg actaaaatca
     6601 atctgaacat gcaactgctt tgctttctct aaaaaatcat caaactattt agattgctgc
     6661 atcaaaaaat aaagacgttg tttcaattca aatttatgac tagattccct atatttttta
     6721 taacctcgat aagaataacg tttctcaata atttttgcac cagccatttt agaaatacgg
     6781 tctgaaatca tacggaggtt tcgttccaag gcatagttcc atatcaactt tttatctgaa
     6841 ttgcggtcaa tagcgttgat taggatgtga ttatgaacat gatctttgtc tgtgtgagtt
     6901 gctacgataa acttaaaacg acctcctgtc aattccatca tggtctcata accaatgcgg
     6961 ttaatttctt caggtgtcag attatcttca ggagaaaatg attggatgag atgatgggca
     7021 tgaatagttt gttggtgttt ttcttgtcgg tcatttctgg actcgtacaa cttgtcgtta
     7081 ttagtaaagt taacattgta catttctacc atttctgtat ggctaggaaa atctaagtaa
     7141 ttactcatgc caaaatcaga tactaatttt agattatctg ttttatctgg attgaggata
     7201 tatttaatca aacgcctacg atattttttt ccgtgcgtcg caaagtgttt agtaactacc
     7261 atgaaactcc ttcagtcttt tcacctacac ttgaaattct ttgtccactt ccttaattaa
     7321 ctctccgact cctttactca attcttgtaa ttggtcctga gaaatcagat ggctttgatt
     7381 aatcgcacgc gcaatttgat tgatgttatt tccaatacgt ctcaattcaa aaactaactg
     7441 gtcataagta tcagtgttaa tcgtgacaaa tgacatattg ggattaagca aaacttttct
     7501 ggcatagact gaaaaatttt gacaattgct cttagcaatc cgttcattca attggtgtaa
     7561 ttctggatca gttagaaata cttttttgag attggtacga tagcgataaa ccattacatc
     7621 ctcctaaccc atatattttt cacgaaactc acgactgagt ggctgtactt gattcacttc
     7681 tgcaatcaat tcttgaacgc aagtcaataa gattgagacg tgctcttgag tcacttgatg
     7741 attttctctt gcgacaacca gaacttcata cacatctcga ctaatctgtt caaacttttg
     7801 agactgccaa agggagaacc aactttcaaa aattctatcc tgataattct ttttcaataa
     7861 attttgacga agaaattctg agaaactatc cactttttgt tccctcatca tttcttttat
     7921 ctgtttttct tcttgtctcg tgattctaaa ttgcttacgg attaacttaa tttcttgtcc
     7981 catcttacca ttctttcaac attatacttg tctgacaatg taaggctgcc tcacattgtc
     8041 agtacgattc ctaaagacct cagtctctcc ttgttcggtc tttgcgagct cagatattgt
     8101 gtccacaata tcccaaaaat catatcgcca gcctatcaaa acctaccagt tttgacagct
     8161 aacgataaga taacttagtg gctccgcccc caaaccccca ggtaaaattc ttagttggat
     8221 ttttaaaagt tgagaaaagt atagcagaag aaatttgggg aagttatcac aaatcaagta
     8281 aggactaatc tctaacacca ctgcatgtac cgtcctatat ttatgatcag ctcccatcgt
     8341 ttacattttc aggtcactgt cttttcatac caggaattag aattgacaaa tttaattaga
     8401 gaggtattca tttaattgtt cacttcttcg ctccatttcc attacagaaa tttcttcaat
     8461 actatgtgtt cagctgactc ccatgattcg ttgtactacg tcctaaacgc tcacggaata
     8521 agccgtacat ctttcctagt ttactctcgt aatttacgta tataggttac gacacctatt
     8581 tggattttag agttcctcat ccgctatata tggcttcaag tcacgattct gtttgtagaa
     8641 ccttgatttc gctaattcct tcctatcccc cctacctcac gatattcagg cttaggagtc
     8701 gctattggtt tcatctgcag caaatatcca cagaggactt ggacctcaga tgtacactat
     8761 gcctgtcgga caaagaaaaa agtaggctaa atttctaacc tactttttct gactctactc
     8821 tgataaagcc gtctcatata tagacatttt atgcttgaag gaatcttttc ctccctctaa
     8881 ttgattgatg atatgatttt ttatatattt ttcactaaca tatccctgtg attcaatcca
     8941 tccgttaact ccatctgact ccataataac aacttgatct gtcatagaat ttgttacaat
     9001 tgtagcatta tgtgttgcta aaataatttg acgttgagct ttcacatctc taaactgctg
     9061 aactaaatgc ctgtaaatat aacgattgtc tagattgtct tcaggctgat caataatcaa
     9121 tggtctgaag tctttagaat aatcactata tgctaataaa aaatcaagca tggctacaac
     9181 tttttgtccc aaacttaata caccaacttc tttatagaga atatcaagtt gttgcgaaaa
     9241 ttctttcgag ttaatattaa actccaaaat cgtgtatttt ctttagaaaa aatttttcgt
     9301 ttatatgcac ctgataagtg agaacctttt ttcaaaatgt cataactatt gaaatgagca
     9361 atatagttaa ctattttttg attattgaaa tccttcatta tagtcagtga atgttgataa
     9421 cttccatctt tctcacttat aatattttca cttaaccatt gattaaccca tgattcttgt
     9481 tcataatcat atatacatac aatatgcaat ttatctgctg cactaatttc tactccatgt
     9541 aaaatatgag gatgtatatc ataaatcgga taatttttca ttatgattga gactgccatt
     9601 tgtaactttt taataccttt ggtagtatta tgatcagtta ctacaactat ttctattcca
     9661 ttttttatga ttgcctctgc taacataaga aaactaatat attcttttga actagaaaaa
     9721 acaaccttat caaaattact aaaaaaaatt gtcttatcaa cttttatttt cttattttca
     9781 aaaaatatat catatagttc atcttcagta atttttctat atttcgttgc agtccaatta
     9841 gaaaatagct tgtaatcata agaaacaggt gtatgcaaat gaattaaagt cttgtgaaag
     9901 ctaccgaatt tctctttgga atttgttagt tcttgataaa cagactttat cttgttatta
     9961 aaccctctca tttctattct cctaaaaata tcaattgttt atttttcaag taattcatta
    10021 agtctctttt cccccacctg caacatctcc ttctctacct gactccactc cccaaagaat
    10081 aactcttgaa gaacatctgc tgctgaagtt gtattttctt ttgaatcata tacacaactt
    10141 ctatctcgtt ggtaaatttg aattctttca aagatagcta gttcttccaa ttttcgtgtg
    10201 ttatcaacta gatgatttac aatgaaatca tgatgttctt ttggagttgc gcgtgcttga
    10261 tttggattga taatgtacag ttcttcataa cggataagag tacttagata cgacaattca
    10321 ggctttgtcg caattaaggc caattgtact tcatatccct tatttttcaa gagttgtgcc
    10381 gttttctttg gaacatcaat tgttcgtaaa gttccctcga tcaaaagatt gtatcccaaa
    10441 ctactcaatt ttgttactaa agactctacc atttttcctg caaaatcttt ggtatattct
    10501 acactgtctt tgccatattc ttgctgcagt tctaaatagt gtggatgctg agaacgaaaa
    10561 ctatcaccat ctatgataac aatatttcct tgaaattctt tctgtttaat acgatgaatt
    10621 gtagtcttac cggcaccact ttgacctcca agcaaaatcg ctataggttg cttactggac
    10681 ttttttcctc ttgtcagtga acgaagattc cttgctaaag catgtttgaa ttcactatca
    10741 gtataatctt ggatttccat taagctacca tccgcttttc agatatctct aacatacgtt
    10801 caattccatc caaatagcca ctatatctct ctatttcatc aaaagtttct actaaataga
    10861 tattcgtatg aatcaaatca gaaagatcat cactcattaa aatccaagga ttagattcat
    10921 catcaatgct aattccctga ctatcttgat agcgatagag tcgagataat agattagcac
    10981 ctctttcttt cacaatttca atttttaaag tcaattcata atcttcaaca ggattgagca
    11041 ttttatcttc tcctacgata tcgacataag atacattaaa cttctgacaa atgatgtcta
    11101 ttaattcggt agagactgaa ctcgttccat tttcataacg actcagacta tttcgtgaaa
    11161 tacctacaat ccgtgcaaat tcgtgttgtg ttaagtcatg tgttttacgt aaggatttta
    11221 tgttctttcc aatcatggca aactccttta tttttataat tcaattatag cataaaaaag
    11281 cataatgcac caaaaatggt gcattatttc ttgtttttct atcctaaact ttacttctat
    11341 aaaagtcacc taaagagcca taaatattta ttcttgtatt aattttttcg atgcgcaaac
    11401 gatatctaca aatacatcta taacgattca ccttttagga tttttattgt caaaattgcc
    11461 tttatctaca aagacaaaat gcttataaaa tagtttgaaa tcaaggatta tcgccttttt
    11521 cgttgtagca acactccaca tgtgattatt aggctattag caaagcgtat ccaatacctc
    11581 aataaagtgt tgtttttact gatattttaa ctatattgta tagtctacta tttaaatctc
    11641 aattaggata ttttatagaa tacccaaaat tcaacaataa ctaaaagtaa gattccattg
    11701 tatttccttg ttggtctttc atatcacgaa ttttattttt cagaatatta aagttacaaa
    11761 tttcatctct aatatcgtta tccgctctgt agccattaat catctcagtc agagttttcc
    11821 ctttactacc attctttata gtagtattta ctctttttat actgctttca aaaggctcat
    11881 atgttttata cttaattact tcgtctttaa aattaaataa aggtgtatcc ggcttagcat
    11941 tccataaaat aatcaaccac attatagcat tataaagctg ctttgcagtt tcattccact
    12001 tttcaggtta taaatttcca ctccctgtat tgtcatattc ttgtctatta tttacatgag
    12061 aatcacctac aagcggatta aaaagaggta gccctttgtg attaattagt tctaaaaaat
    12121 cccttgccgc acccatgcaa cactgaataa cttccttctt gccatcaatt ttactctcag
    12181 cgataaatac ataatattca tcttcaatag ttgctactgc atcactatgt ttttgttgat
    12241 ttgctaacag cttaatatgt actttaggct gaacttcaaa atctctaaca attctttgtc
    12301 ttgtttcatg tcctctacaa ttcatttaag ttctccttta caagtttagt aactagcctt
    12361 attatactat ataaggtatg aaatgtacca taatcttcat caactagttt ttagaaaatc
    12421 ataaatccat ctggagagat gacaagctga ttatccaatt cttggcaatt gcttgctagt
    12481 gctactgctt ctttctctaa aagataatct tctgttgatt ggttgaatat tgctttgagg
    12541 atccgtcctt cgtatttcca ttccagagct actagatcag agttgatttc ttgaaggcta
    12601 tacttgccat gcgaaatgat tactgacgcg tatttccgaa tcttaatcag cctcttcata
    12661 aagttcagca tatcattgtc acttgataca cgttcccaag gcatacaacg acgacaatct
    12721 ggatctggtc ctccagtcaa ggctagctcg gttccgtaat aaatgcacgg tgttcctttt
    12781 tgtaaaaaga gaaaggctaa ggctgattta accagttgaa catcttcatt ggccgtccac
    12841 aggattcgct ctgtatcatg tgaatccaag agattaaaca tgacctctga aatctgctgc
    12901 ttgtaataca tagactctcc attgatttca tcgatgaact ggtctgtctt cttaattcct
    12961 cgtaagaaat agtccttgat actatcagat aaaggataat tcatgacggc atggaactca
    13021 tctccattta gccaaggctg agatgtatgc cagacttctc ctaggatata aagatcagga
    13081 tttttagcta aaactgcctt acgaaaatcc ttccagaact gatggtcaat ctcattagcc
    13141 acatccaaac gccaagcatc gatattaaac tcttcaatcc aataagtcgc aacctttaaa
    13201 agataattct tgacctctgg attggctgta tttagcttag gcatatagtc ctcgaaacca
    13261 aaaacatgat agggtaagtc tctcttatta actagctttt cagttgtcac tgggaattgt
    13321 tgaatatgga accaatcctt ataagcagac tgttcaccat ttttgacgac atttttccat
    13381 tgaagagatt gcgaaccaat atgattaaat accgcatcca gcatgacttt catgccacga
    13441 tgatgcgctt gatccaccag ttcccgaaat gtctccttgt ctccaaaatg acggtcaatt
    13501 tcaaagtaat ctgtcgtatt gtacttgtga ttgcttgcag attcaaagat gggacaaaga
    13561 tatagtccag taatacccaa gtcttgcaag taatccatat gatcaataat cccctgtaaa
    13621 tcaccaccaa agaaatcatc gctcttaggt gtgacagatg aatcccagtc taaagtccct
    13681 tctgggttta atagagcatt gccattggca aatctttcag gaaatatctg ataccatacc
    13741 gtatttgaaa cccagtcagg aactttgcag gcatcaatct catgaagata aggcaactta
    13801 aatccattcc caattgcatg aagattttct agagaatttt ccacacaccc tttatcgcca
    13861 tacaaaatat tttgaccttc tgtatctctg agctcaaaga gatactggat acgtgcaaag
    13921 tcaactgaca cttcaacctg ccaatggtca aataaggtac cagaagttat cttgaccatt
    13981 tcttttgtat cctgataaaa ctcctccata aagataaaag ggtccccata gtgcaagttg
    14041 atgctttcaa tgtccccttt cttagttcga attcgaatat ggagtttctt atccttataa
    14101 agataggcat actccgactc aggcctatgg taaatagcac tcaattccat caatttgtct
    14161 cctaaagtat tcattcaaat tttacgcaaa cgttttcaaa ctcaataaat ccagtatact
    14221 atttttgtaa actatttgca aggaatgtcc gttgttaaag gaactatctt ttaaagtata
    14281 caaaaagcct taaaaaaggc tttctctata tactaatcct ctttcagttt tgaaaatact
    14341 tctactcgct gagctaggac tttgatttct acaggtaggt tatctgattt atctccgtca
    14401 acatctgact ccaattcact atctgaagag attttaatat tacgcgcttt gatatactcg
    14461 atattatcat ttgcgacaac atcccctttt aataaatcag gaatgacgga taatttggag
    14521 aatatagagg catctttcag aatcaaaatg ttggcatagc cgtccttgtt ttcttcaaag
    14581 attttcttat cagcgaagta atttgtcaaa aggaccaaaa catggatagc ttcaccaaca
    14641 taatttccat tttctgtctc aaccttaatg ttaaagacct gatctgtcat gacagacttc
    14701 atggtattta cagcataggt taaaataccg aattttgttt tgtcctctat ttcaacattg
    14761 tgaatcgcct caggcagaga accgatacta aagatataac caaaatagtt gtcatttgct
    14821 ttaccgatat caatcttatt ggttaaatca aaatccagtt cgtcaattgc gccatcgatg
    14881 tcttgattga tttccaaaag ttttgtaatg aggttacccg taccgcctgg gataatccct
    14941 aacttaggaa tgtagtctct ctcatcaata cctgaaatga cttcattgac agttccatct
    15001 ccaccaaaca caaccactgc atcatactgc tcacgagaag cttcttcagc aaaatgtgtt
    15061 gcatccagcg ctttttcggt aattttggtt tcaacatatt caaagtattc ttttgcttta
    15121 ttctccagct tttctttgta atccaaagcc ttctcgccac cagaagtagg ggtgataatt
    15181 accattgctt ttttcattga ttttatcctt aattttaaac agaaatgttt acatttcgtc
    15241 gtatgcaagt aaatgtaatc ctattataca atgaaaatac agaaaagaga aatctgacgt
    15301 actggagatt aatacgcttt tattctattt tcccatcgcc taactacatc ctttaagggt
    15361 tcatccaagt aagaataggc cttatccttg atccaatcag gaataccgta agctgcctct
    15421 gctatgctac aagtgattgc tgcgagagta tcactgtcgc caccaagtga gatggcattt
    15481 cttatcgcat cttcgaagtc tctactttca agaaaggcga taatggcttg agggacagtt
    15541 tcctgacatg tttcgttaaa acgatagtta ggacggattt catctaaagt ttgagataga
    15601 ttgtaatcgt attctttttc tatataatcc ttaattcgtc ttttacactc tgtaggattg
    15661 tcgttaattg attgctcgta ctctctacaa taaccaccaa agtaaaaacg acatagaaag
    15721 atagcatcag ctgtagccat agcgcctttg acaccttctg gatgattatg agttacctct
    15781 gcagaaagac tcgtaagtcc tctagatgat ggccatatac cagttttcgc ataaaaacca
    15841 cagtccatga tccaagcaca tggagaaata cgcatagctg atccattccc aaagctatta
    15901 taaggctcac ggttatcgct gtttagccat gcattaaacc gagcaccgta atcagcattc
    15961 ggatacattc tgccatattt cttcatcgcg tcaatgaagt catctttttg tccaccattc
    16021 ataattgctt ctgcaacagc acaggtcata accgtgtcat ctgtaaaaaa gcagtccttc
    16081 cgaaataaag gaaagtcctt tgttttgata ttgttccatt cgtaaacaga accgacaata
    16141 tctccaataa ttgctccaag catcagattc ctccttgttc attttgatgc tttttatatt
    16201 ggttatctac catatttatt ttagaaaata acatcctgtt ggattttaaa aatttcattt
    16261 ttttcaaaat agggttttac catttctttc cacctagctc tatgaaaatt gattgatttt
    16321 aaaggagata ggccataatt tcccaatgca taaccatcat ttacttcaac aacaagtgtt
    16381 ctgccatcgc gagtaacacc gatatctagt ccataagcta ttggcgcatc tttccaacat
    16441 gatatcgctt catcaattac acttgcatca aattgtgcat gataatcacc tgtatagggt
    16501 cgaacatcta atacgcgacc atctaacaca aaacaacgcc attcagctat gaattctaca
    16561 acctcactaa tccatatagg atagtcgaaa ggtagaccaa tacctattaa atcatgggtt
    16621 ccattaacaa ctcttccagt aaagactttt gaaccagctt taggcttaat aaattttccc
    16681 caattatcag gtatattcac aatctctcct aaaataccag cataaatctt tcgaccataa
    16741 aactctttaa gctcaatagg atagtcatga accggaacgt ttaagcccat catttttagt
    16801 aatgctctag tctccattat ataatctaca actatatctt cacttgttaa ctcttttatt
    16861 tcagaaaaag attgatataa aataacttct tctccttgta agtaggcacc tacttgagca
    16921 ttgtatttat taattgaaac ctcacttggt aatttacttt gtctaatata aacaaccatt
    16981 tcatcactcc tatatcacta gtgttacacc aatttgtaaa aaataatagc aattttgctc
    17041 ttattttttt gagtaaatag cccccataat atcatcgaaa taatcaacgg tatttaggag
    17101 taattcaata acctgggact ttgttagtcg cattcccctt ctatctctag catcttctac
    17161 taaattttca agtttctcta gatttttatc atccaagcta atcattattc tatttttatc
    17221 ggttgccatt ttcatcacct caagttaatt ctatcacagg tgtaacacta gtgtcaactg
    17281 gcttttataa tacattagtt taaaagtgga gaggattttt aacacagtaa ctttaaatct
    17341 ttggtattaa aaaattttca caatatttat agaaataaaa tctgtctcaa atcagttatc
    17401 aaatctagta taaattatga gcggctactc taatactttc cctctaaaca agaaaaagac
    17461 ttacactcaa gggttttctt cccccccttc gttataacgt tttgactctt ttactagcaa
    17521 aggtatatac tcacaaggaa ctttggttga ctattgaatc tctccaactt cttctttaac
    17581 atatccttct acatcttcaa tctctacaaa cattgggtct aagtgacaca agaaatgcca
    17641 aacttcgatc cctttttttc tgtaaagaat cgcttcaccg tcttcacttc cgaaaaagct
    17701 tctgtcgatt tcatatccgc ggctttctaa gaagtctttt gctttacgat agttcgtttc
    17761 tcttgtttcg acataggctt taacttcatg gttgttaacg acatatgcat caatttttga
    17821 atatccttcg atcactctat catttttgag ggataaattt gaaatctctt tccaaataat
    17881 gtttacattt tcctcaggat cgaacataaa tttagataaa ggaacaatat ttccgttaaa
    17941 aataatttcc atataatccg gtatgttttt aggattaaaa tactccactt caaaaccatc
    18001 ttctgtttcc agagtgtatc ccgggatttg agctacaaag gctttcccat cttctatgga
    18061 atcaaatgct actaaatctt tagaataatc attttggtac aattccaata taaccatcga
    18121 taatctctcc attttcatta tcaggctaat gtaaataagc acgtcacctg accaattcag
    18181 gctctctgta tcatctcatc atatttccta cttactttac gagtcttata cccagaacac
    18241 accttatcga ccttcggtct cacctcgtcg cattggctga acatctactt ttactttgct
    18301 gatgcttcaa ctcgtacaag cagtgatacc gcctcagcgt gatgcgtcag tgggactcaa
    18361 aaggttcggg gaaccttttg aggattaact acgtttctct aataaactta cacattcaac
    18421 ttgttcatca ttgtccaaac ctatgttgag attttcttct ataattggta gcttaaaagt
    18481 aatggatttt agccattgtc cgttagattg tttttcttca taaacttgaa tttcagaaat
    18541 caaagctgaa attaactgcc tacgctctac atcattcatg actttataga gcttatcaaa
    18601 atagatcaga accttatata tgttatctcc tgtaagcttt tcagcttcaa tagtctgttt
    18661 ctttgctttc gcatcaatta gtgatgattc taattcatct agtttgtcat acatacgata
    18721 tagtctatca tctaaatcct gtttccttct cttataatgc ttatcttcaa catctaaatt
    18781 atctatttcc tcaattagct taaactttgt agaatgactc tttctcaatt ccttttggta
    18841 attatctatt tctctttcta tttcagaggt atccaccttc atgttgattt tttcttgcat
    18901 catagaagca aatttcggat tacttactat cttgacaatc acctctgcaa cagcatcatc
    18961 taacaattct tctctaattt gcttactgaa tgtacactta tgacctctta tcatctgcct
    19021 atgtttacaa ccatagtaat aaaaatcttt atactttgtg ccatctttct ttttcttgat
    19081 acacttgttc ccaaacattc ccactccaca tatcgggcat tttacaattc cagaaagcaa
    19141 gtgtgtgcgt gtatcttttc ctttattcac atgctcatat ttctttgctt gagattttag
    19201 cttaacctga gcagcttacc aaacttcatc ggaaactata gcttcatgta tcccttcaga
    19261 tattagatat tcatcttgtt caacctgctt atattcattt cttgtaccat gaactttttc
    19321 taaagttctt cttccaaatg ctattttccc attatataca ggattcttta atatctttct
    19381 tataagacct gcatcaaaca aaggattctt accattctgt cttgggattt ttctaattcc
    19441 atgattctct aagtatttag atatcccatt ggctcctatc gtagtattta catactggtc
    19501 gaaaatcgtt cttattgcaa ctgcctcttc ctcatttata aacagcttgc cgtcttcaag
    19561 tttatatcca tacggagcaa agccaccatt ccattttcct tcccttgctt tttgaatgca
    19621 accttccatt gtttgaatac ggatgttttc tctttctatt tcagccacag ctgataaaac
    19681 agaaatcatt agtttcccag catctttaga tgaatcaatg ccatcttcaa cgcagataag
    19741 attaactcca taatcctgca ttatctgaag tgtataaaga acatcagcgg catttcttgc
    19801 aaatcttgat aacttaaaca caagaacaaa agatactcca tcttttccag attttatatc
    19861 ttccatcatt cgattgaact gtattctacc ttcaatagac ttgccagact tcccggcatc
    19921 ttcatactct ccaacaattt cataatcgtt gtaaatagca aaagctttca ttcgtgattt
    19981 ttgtgcccct aacgaatacc cctctatctg tattgacgta gatactcgtg tatagaggta
    20041 tacttttatt ttttcttttg acatagtatt aacctcaata taatttttct atatcatata
    20101 taattttttt aatttaagtt tggactatca tttcaagtat attataacac ttttattagt
    20161 ccgtctcaat ttgtgttttt gccatgtcaa aactattttt catctcttga ttttttgctg
    20221 gcgttggatc gggtagatta tctaaatcta aagcaccagc atattttgca atcagatttg
    20281 ctattaaatc agccaatcca ttccagtcat tgttcaatat atacctcctc taaagtttta
    20341 tatctaataa ttatttgttt aattaagttt tttgacattg acaagtgctt tggattagca
    20401 acataggaat ctcacctccg cctctattcc ggatgagccg gcttcaacct tagaagtatc
    20461 attatcctca ttttcttcat agcggatagg gtatccctcc ctatattcaa actcttactt
    20521 atcgctcact ttctttttgt ttagcagaac tttttttgcc gaattattca gccgaaagat
    20581 cttgacggat aggttattac gctccaaaaa taattaacgt cttgtcttgg tctattcaat
    20641 tgttaaggtt caaaatttat cgaaagttat taatcttttt aaaatttgac catcagaaaa
    20701 tatttatctt gatgtaacaa aattctataa attaccctct tatacttaac agtgaaaaga
    20761 agtctttctt ggtaaccaat tttgaaatag aatttgctta tataaaaagg tccaattccc
    20821 actgcataag tagcagtgaa aattagaccc tcttggtaac tgtcatctaa aagtcttcta
    20881 gcatttcttt aattttctaa tcgcctttaa agtgtcatat ttatattttt ttatctctgg
    20941 catactttga taccttttta gacttaaagt ctttaatagt gcctttccac ctctttttat
    21001 ctataaagat tctcctacat cataattcat ttttttattt aaacctttct gtcttagttt
    21061 gtctttatct tcttcatacc attttaagat tgtcacatag tggttttgat aggtcttacc
    21121 actgctttcc atgtatctgg atagtttatt tatcattata tctgtgtgtg agtttaattt
    21181 ttcttttaga tttttatatt cttctttgct taaccttaca tttttgaatt ctccataaaa
    21241 aatgggggtg gactttttat ctatctctcc ctctctctct ttatctatct ctatatcttt
    21301 ccatgtaatt ccaatctgga gtacctctac tgtctatcgg taatttaatt ttgatatctg
    21361 gcaatactgt gctagatatt tgatctttat attcagtatt ttttaaagct tgcctaataa
    21421 ttgaagttaa atagaatgct acttctttat tcaattcttt attttttaat tttaaacaat
    21481 gaattttcat atctaggctt gctttatatt tatgataaaa gactgctcct aaaaatgaaa
    21541 cagatataaa attttcaaaa actctataat ttttatcatc tatatcttcg tagtaaccta
    21601 agataccatt gtcaatattt gtagcactaa ttctaggagt ttttccatcg agtaaatatc
    21661 tttttggaat agatgagcct gttggtactt aactcgattt cccctttttt tcggtaataa
    21721 atatttcttt ttattttgtt gtctgatatt tttcctacct gtcctttgta ggatgagtat
    21781 tttctagatt ttcttgaata actttttact tgaagtttta gcttttgaac tagtcgttgt
    21841 actttctttt tgtttattat cagtcctgat ctttttaata ttgctgttat tctctatatc
    21901 ctatttttca ttcatgatat tcttttacta attttatctt aaattctgtg ctgtatttgc
    21961 cattaaaaaa ctgacctcct ttagttagtt ttttggccta acttttgagg gtcagttcaa
    22021 aatttgcgac ttttaaatga attccaatat tcaattatta agagttaaca tggtgcttgc
    22081 caataggaat cattagaggc gaattggaaa tagggtcacg tataattttt gcttcaagat
    22141 taaagatatc tttaactagt ttatcattta gtatatcttc aggctttccc tctgcaacaa
    22201 gtttaccttc tttaattgca aataggtaat cagcgtatct tgctgttaga tttatatcgt
    22261 gcaaaatcat gcaaatggtt gtcttatatt tttggtttag atcagtcaag aggtctaata
    22321 gttctatttg atatgagata tccaagtaag tagttggctc atctaaaagt aggatacttg
    22381 tatcttgggc tagggctaga gctatccata ctctttgcct ttgaccccca gaaagttctt
    22441 caactaggtt atttgctaga tcttcaacat tggccttaac cattgatctg tttattattt
    22501 caaggtcatc ttttccaaga ctcttaaaag gctttctgta ggggaaacga ccacggctta
    22561 caagatcagc tactgttatt gattcaggga ttattggaga ttgaggtaat atagctatgt
    22621 gttttgctaa atctttttct ttataagaat taattgattt attatcaagc aatacttctc
    22681 cctctaatgg ctttataagt cgagacaagg ttttaatgag tgttgatttc ccacaaccat
    22741 ttgacccaat aataactgat attttttctt caggtatttt tatatttata ttttccaaga
    22801 ttattttttc atcataaccg caggtaagat tatttgacca cagacctttc attatatatt
    22861 cctcctgttc atttttatta gtaagtatat taagtatggt gaacctaaca agccagttac
    22921 aacacctact ggatatctag ctggtaaaat attttgagag aatatgtctg ataacaaaac
    22981 tagtaaaatt ccaaccaatc cagctaatat tgggcttctt ttcttgccaa tatttaaggc
    23041 tatgggacca gctaaaaaag atatacaagc tattggtcct gtaattgaag tagaaaaagc
    23101 agttaaagat acagcgcaaa aaattaaaac aagccttgaa agctcgggat ttgctccaag
    23161 tccgattgct atttcttcac caagttcaat aatttctagt cttttattaa aaaataaaac
    23221 taatatagta gcaataatac ttactattag aacaagaggt atgtcatcta actttgtaaa
    23281 agataaagag ccactgagcc atctcataac ttcttgtaat tcatatcttg ctactttcaa
    23341 caataaaaat gaggtgcctg ctcttgtgac agcttgaaaa ccaataccta atattatcag
    23401 tcttgctgct gaaaaaccat cttttttagc tagtaaaaat aatattaaag atgatgttag
    23461 tccacaagtt attgaaataa ttccagtagt taaactattt gtttttaata ccaatatgca
    23521 aaagaccgct gcaatagatg aagaacttgt gacaccgatt atatcaggac ttgcaagagg
    23581 atttcttaac atagtttgaa agataaatcc tgccaatcca aaagaccagc cagctataat
    23641 tcctgctaat aattttggta atctaatttc cataatcgaa aaactagctc caggaacagt
    23701 ttcactattt aagactttaa tcaaagttga aaaagaataa ctttcatctc cgataagtaa
    23761 aatgaaaaat gatagactga ttattattaa taaaaatagt gaggaaaata gtgttattct
    23821 attttttctt ttttgaatac ctataattaa attttgcatt agttattaac ccctctattt
    23881 ttcatagtta cataaataag tactggaccc ccgattattg cagtaattat ccctacttca
    23941 atttcacctg gtttacctaa catacggccg attatatcac atataagcaa gagctctgca
    24001 cctataaaag atgaagaaat ggtcattgtg cgtatatctt tgcttataaa taagccacaa
    24061 aagtgaggaa ctataagacc tacgaagcca ataggtccac caattgcagt aatacttgaa
    24121 cataaaagca cacttgcaat tattgcaagt gatcttatcc tattaacatt aactccaaga
    24181 ccaacagcca tttcatcacc catagctaaa gcgtttaaat ctgatgaaat aaatatagct
    24241 atcaagtgac ctaaaattat aaaaggtagt agtgtagata tagaagataa tgtagctgct
    24301 ccaaggctac ctatttgcca aaatctaaat ttgtctaaga cgttattatt cggtaaaatt
    24361 aaaaaactta caaaactgct taaagccata ctaacacaag ttcctgataa ggcaagtttt
    24421 ataggggtaa ggcctgcttt tccgcttaca gcaatcgcgt atacaaaaat tgcacttact
    24481 aagccaccaa tgattgcaaa acttatatgg cttatgcttg atgaaattcc taaaaaagaa
    24541 agaccaatta ctacactaag acttgctcct gtgtttatac cgagtatacc tggatcagct
    24601 attgggtttc tagtaactga ttgcatcaat acaccgctta tggcaagact agaacctgct
    24661 aaaattgcaa aaatagttct aggtattctt ttatatataa ttgatttaat aaaatcatca
    24721 tttgtattgc ccattccaaa agctgctaaa aaatctctga tattaatttc ttttgttcca
    24781 agctttaatg acaaaaatat tgtaataaga agacctaggc agattacaaa aattatgcct
    24841 aggtttattt gttttttatt tcgcattttt gcatgcattt cctaaaagat ttaggtattc
    24901 ttcaatagta tagtttattg aaagtggtgt tggagtgcat gaggctgcta acggtgtatt
    24961 atctggaatt acagcaacgg caccattttt aattgcattt attttaccta aaagaggatc
    25021 tttttgtaaa gcttcaagag ttttatcatc accataagtt atgattacat cagcatcatt
    25081 tatcttattt gcttcttctg cagaaatttc ctttgcaaaa ctatcttcac tctcaaattc
    25141 ttttaatgat tcagggaaaa ctagacctaa atctgttaaa taatttgctc ttggatcttt
    25201 gctagtataa atccagaatt ttgatgtatc tgcagcatta atcatagtaa ataatacttt
    25261 ttttcctttg atttttcctt tgatttctgg atgtttttct aattctttgg atatacgagc
    25321 ttcagtattt ttgattaact catcaccttc tttttccata cctaaggctt ttgaatcaat
    25381 tttaatcata tctctccata aagtttgcca aggtttagat ttgtatgctg ctacaggagc
    25441 aatttttgat agagtgtcat aatcttcttt agttatacca gaataacctg ctaagataac
    25501 atctggttta gaatttgata ttgcttcaaa gttaagtcca tccaaatcgt caaataggtt
    25561 agctttacca tttagttctt tgattttttc ttctgtccat ggtaaaactc ctttatcagc
    25621 acttacaccg taatttgctt ttgaaaatcc aacaggaact attcctaaag ctaatgctac
    25681 atcatgattt ccccaagcaa tagttgcaac tctttcaggt tttttatcta atatagtttg
    25741 accgaaagca tgatctaaaa ctattttatc aggcgcatgc tctttagaag tattttcttc
    25801 atttttaaca gaattagaag aacaagcgct aaaaactata cacatagcta aaatagctat
    25861 tagaaaaaat ttgtttttca taaaaactcc ttaaacatat ttcaagtcta ttgtatcgat
    25921 aataattatc attgtcaata gatacagtta caaatttaat aatataattt tttcaaaaaa
    25981 ggatctagtt tttattttta gttaaattat gtctatattt ttcattaact catcaataaa
    26041 aatttgtttg ctaatatctc tttcttctga ttttgtttca aggattattg ctacatcatt
    26101 catattttta ggtaaatacc aaccatctgg cttatctgaa tatcccttga agcctaattg
    26161 attaaaagta gttatttgac cagtaccttg attgatgttt tcttcaactt cattaaagcc
    26221 tatacttctc ttgcataatc cctaacttga tcttctgtcc ttaaagtcat tttctattcc
    26281 tcgtcactaa aattatcttc aaaactaata atatcattag gagtgcaaga taaagcctta
    26341 catattcttt ctaaattctt aaatgtaatt ggtttatcct ttcccatttg tgccataaca
    26401 tttgttgtaa gtcctgccat agctattaca tctgttttct ttagtccttt ttttgctaac
    26461 tgtatccata atggtttata gttaagtgcc ataatatccc tctttttttc ttcattagat
    26521 ttatttaatt atagcataaa tattgatttc attcaatctt acattgattt agtgatttgt
    26581 tttagagaat ttgttgtgtt attccgtcct tattttgcca taaattgttt taagtgggac
    26641 ctcttatcct taccattttt acctcctaat tttgagtata aaaaagacga tagagttttt
    26701 aatttctatc gtctgagatt tacatattaa attttcatca caaaataaga ctctttaaag
    26761 aatctttaaa ttcattggta tgctgcttac aatatccatt attaaaatgg atattgtaag
    26821 cagcacacca actatttatt ttttgagttt taaactttgg tagaagtctt gaactcctta
    26881 tatttacata actatttgcc tctataactg ttatgacacg aaaccaacaa gcaagttcaa
    26941 gcacctccat atctttattc aaatgaggac taagatattc acaaacttta tcataaacct
    27001 ctttatcttt tttcataaaa ggggcataca acttagcaaa tttatcctaa aattttttgt
    27061 tgcctttatc aatcatttca acgctccttt aaatataaaa atgatcctat caatctttat
    27121 attgagccta ttttctaatt gataccttgc aagaaaggaa taatagctgt tcctatacca
    27181 agtaggaatg taataaatgc agaaagtcat atactgtcat tcttttctat taaatcattt
    27241 tgaagtgtct caaagcatcc atgatggctt cttctttttc aggtgtacac tgtggaataa
    27301 tttgtttatc ctttttagac ttgttgtaat gttctcgtaa ttctattcca catttctttt
    27361 ttatctgtgc aatatataat gtcgaaactt ttaattcaaa tttattccaa acatattctt
    27421 tgatttgagc atatgttgct ttgctctccg cacttgtcaa atccatctca tccagctcaa
    27481 tttcaacact tatgtgctta tcgacatcga gtttggacaa aagtgctacc gtctcgacgt
    27541 gatgcgtttg aggaaataga tccaccggct ggactttctt caattcatat cccaactctt
    27601 ggtatagttt aatatcacgc gccatggttg cgacattgca ggagatatag gcgatgcgat
    27661 cggctcctgt ttgggcgctt gctttgataa agctttctgt caagcccttg cgtggaggat
    27721 caaccaagat aacggttggt tgaatacctt ccttgagcca tttcttcatg gcattttcag
    27781 ccgtgtcaca gacatagtgg gcattagtaa tcttgttcaa agaagcattc ttctggctat
    27841 tctctactgc ttctggaatc agttcaacac cgtagacttc tttgacatgc ttggcgactg
    27901 ataaaccaat ggttccaata ccagaatagg catcaataat cacatcatct ttttttaact
    27961 ctgcaaagtc aatggctgtt tgatagagtt tctccgccat ttcagtattg acttggtaaa
    28021 aggctgggcc agcgatttgg aagtcatttc ccaacatctg gtccgtaata tagtcttgac
    28081 cataaagagt gcgccactcc ttaccaaaaa tcgcattggt attctggtcg ttgatatttt
    28141 gcatgacaga cacaatctct gggaactgct tgataacttg ttcaatcaat tggtcaacac
    28201 gaaaaacttt tggacgagtt gtcaccaaaa cgaccatgat ttgtcctgaa tagtgaccac
    28261 gacgcaccac aagattccga atcaatccag attgttcctt ttcgtcataa ggttttaaat
    28321 caaaacgacg gagcaggtct cgaagagcta ctacgacttg gtcaatgaca ggatcctgga
    28381 taaagaaatc ttcaaggggc atgaggttat gcgaattctt acggaaaaat cctgtttcca
    28441 agacaccatt cactcgacga acgggcacct gcgccttatt gcgatacttg actggatgtt
    28501 ccatatcaag cgtttcagca acttctacat ctgcaattcc agcaatcttg tagagactgt
    28561 ccttgacttg cttggtttta aacttgagct gttctggata agaaaggtgt cctaaatccg
    28621 cgattcctga acgcaggtaa gccaaatcta gatcttgatt acggtgtggt gactggacaa
    28681 ggtatttttc aacttttcca aagccaatct ttttattgac cttgaggaca cgcatgagaa
    28741 ttttttcact cggtaaagca ttctctacaa aaaagaccaa accatctacc ttggcaactc
    28801 ctgccccttc atgggtcaaa tcaacaattt caacttctac aatatcattt ttctttaaca
    28861 ttcttttctc tttctattgg ccgacaaaaa agacggcaac gttacggtta ccatccatta
    28921 taccatgaaa tttcttaaga accaaaactc ttgaagaagt tgacaagggc ttgccagagg
    28981 gagcttaaga agttaccacc gtcctctagc gccttatccg catcaaagtt aaggttgata
    29041 tttttaaaac tgtcgccagc ttgtgatacg atgctttgtt taaggtcatt tagggtttta
    29101 gtgaaatctg cattgctgag gatatcactc tttgagagat tcaaggcaaa attgatgatg
    29161 atattgatct ggtttcctgt tatgacctga tcaagtttgt aattttttaa ggtatcttca
    29221 acaatcttgc gtacatcttc ttctgtcaga tttcccttgc tttctttagc tttggcgagt
    29281 cctgacttga tatcagctag ggcaacgttt aatttattag catcatagcc tgatttgtcc
    29341 ttgttttcag cattgatatc tgacaaagcc tttagctctt cttgagccaa atctttattg
    29401 gcttgcggca ccttggctcc attagcttct agcgaatagt agatcccagc caaagcactc
    29461 tcacctgtaa ctggaatagg ggctgctaca gtgattttgg catgttccat acccagcgtt
    29521 actgctgcgt ttcggtacat atcctgagtc accttagtga tattttctgg tgtttcaatc
    29581 ttgacctcaa gtggcgattt gtcacctagc ttttgaatct tggctgatga atacaactgt
    29641 aagctagagt cattggccac attcatgatt ttagaataaa catcaggtgt catggtcttg
    29701 agttctttgg tatctgttga ggcattgtag cccagttttt taagagtttg atttttttgg
    29761 tcttcagata gggaggaacc taggacatat tcaggttgga cataggtttc atcgataact
    29821 ttttgaacat ctgttgctgc atggacgcta ttcatagctg ttactgccca caagaccgca
    29881 gcactagtca gaaagagttt ctttctcata gggaatttcc tcctttacct ttctagagta
    29941 atatatctat cttaaagaaa acttataaca aaaacacctg aactagccag atgttgaaaa
    30001 gagagtgaaa catttgatga tgtaaaggtt gagttgcacc tgtctagaat aataatagtt
    30061 tcctccattt acatagagtt cggcaccgtg aaaaatggaa atgggatgaa tataactata
    30121 agtctttcca gtcgtattac caagcaaggg ggcaacagtc tcacgagagt actgtttggc
    30181 tagagccaag gtattttcct tgccattttg ggcgataaaa tcgatatagg caggtccaaa
    30241 attataggct tgaacagctg tccagatatc tacacccttc ttctgcgcca gatagagatt
    30301 gcctgtcaga gtttgaatgc cttgccgaat gctagaggca ttatcattga tggtgttggt
    30361 ggaaccactt gcagactcac tagactgcat aacatcgcct tcttttcctt ttgtttcagt
    30421 ataaatcata gcaagcacaa gctcttcgtt tgctggggtg tctttttcac tcaatatttc
    30481 tcgcaccatg ggttgatagg tcatgacttg tttgacatct tgatgaacgc ggtaagcttt
    30541 atagccagca aaaaggaaga ctgctagtac aagcactctt cgaattcgtt taaacattat
    30601 ttactttgga tatcctcgat atttttgatt aagatagagt aggttccatt ttcgttttgg
    30661 ataaactcaa cagactcggc gtcttgatag acgttattgg gaacgatgag ctcaattcca
    30721 tttgataagg agagtttttg gttttcaaat ttctttaatt ggcgactgac atcaatttca
    30781 tcaaattgaa caggttctgg tacggcttct ttgacttggt caataaagct caaacgagcc
    30841 gtcagattgt tgtcaaaaag gtcattagcc aatttctcag gtgacaattc attgctttct
    30901 tctaggttgt tgaaaatagc tgatttgacc ttggattgaa attgaaaatc atctgtgtta
    30961 aaagattcag caattctctg ggctgttttt tccagttcct tgatagattt tttaggagaa
    31021 atcttaggag cgacagcaag aagattatct gaaaaatagt tcaaaaaagt cccgttgtac
    31081 ttgattcgtt tttcaatcag gtgatacttg ctactctgaa gattgaccac caaggcctca
    31141 tcagctcctg ttccaaatcc aggcaggtta ttctgagtta gcttgattgg attatcaact
    31201 tctcctccga ggtgggtcaa ggtctcccgc agggcaattc gcaagaaagc gaaatgttct
    31261 acaccttctt tagaaaattg aacaaaaatc aagtcattgg tcttgagatt ttcagaaatg
    31321 ctaaactcct ctttccagag attagccagc gttactgatg tctccaacaa atcgtctgta
    31381 atatgattga agaagggatt ttcttcttcg aaaatcccag tcttggcttc atctgaatac
    31441 acatgttcaa tttttttacg caggtattct tcgatttttg gagtaatatt gagaaactta
    31501 tctgctaaga acagttcggt atcatccgga ctgaactggt gaataatggc tttcttaata
    31561 taaatgtcca taaaagtttt agtcctcgta tagtaggaag gcatctgtca attctttgac
    31621 tgcacttctc acttcttcta atacagcctc attttctgaa ttcttaaggg ttttaatgat
    31681 gagttcagcc actttgcgac tttcttcttc accaaatcca cgtgcagtaa tggctgctgc
    31741 tccgatacga atcccacttg tcttgaatgg tgacaagctt tcgtaaggga ttgagttttt
    31801 atttaaggta atattgactt catccaacaa gttttgagca actttgccgt tttctacaac
    31861 tttagtcaca tcaacaagga agagatggtt ttcagttcca cctgaaataa tacggaaatc
    31921 agggtcttgc aagaagacat ctgccatagc cttgctgttc ttaattacat tggcagcata
    31981 ttccttgaag gctggatcca aaacttcttt gaaggaaact gccttagccg ccacaacatg
    32041 ctctaaagga ccgccctgaa tacctgggaa aatagctgaa ttgatttttt tagcaagttc
    32101 ttcgtcattg gtcaaaatca aaccaccacg aggtccacga agggttttgt gggtcgttgt
    32161 tgttgtgata tgagcgtatg gaactgggct tggatgaagg ccagccgcaa ccaaaccagc
    32221 gatatgggcc atgtccacca tgagcttcgc accgacagca tctgcgattt cacggaattt
    32281 tgaaaaatcg ataatttgag aatatgctga agcaccagct acaatcagtt ttggttttac
    32341 ttcttgggct tgtttcaaga tagcatcaaa gtctaagagt tccgtttcag gatcaacact
    32401 ataagaaaca aagttgtagg tttgaccaga gaagctaaca ggagccccat gagtcaaatg
    32461 accacctgat gccaaatcca ttcccataac cgtatcacct ggctcaatca aggacatgta
    32521 agccgcacag ttagcttggc ttcctgaatg tggttggaca ttggcaaatt tagcaccgaa
    32581 aatttctttt gcgcgttcaa tagcaagagt ctctacaacg tctactacat cagttccacc
    32641 ataataacgg cgtcctgggt aaccctcggc atatttattt gtcaagatag acccttgagc
    32701 tgccataaca gccttggaaa ctacgttttc cgaagcaatt aactcgatat tattttgttg
    32761 gcgttcttct tctttggcaa tagcattcca gagatcagca tcatatgctt taaaatcatc
    32821 tttgtcaaaa atcataggtc ttctccttta ttgtgtgact agtccattag tttgatttta
    32881 caataagaaa atcaaactaa aagatgcgaa taaaccgttt ctgcatttta tcacaagtat
    32941 agccaacttt ttcataaaat gcatgagcac ccagacgatg attggcagaa tttaagcgga
    33001 taaacccata accacatctt tttgcttctt cttccaaccc ttgtagtaaa cttttaccaa
    33061 taccttgacc ttgcgcttga ggtgaaactg ctaaagctaa gatattaaat cctgctttgg
    33121 aatagagtga ttcgtaaact tcagcgtgga catatccaag taagacatga ttagctgcat
    33181 cctcatagcc aagtaggaaa tgatgggaat cctgagacag tctagctagt tggctagccg
    33241 tttcctctgg actaaaagta taacccaaag cctcttggtt gatgtcacat atcgctttca
    33301 catctgtttc ttgcaaatct cttagcattt caagcctcct caaaagaaat ctctggcaac
    33361 cgagcaagaa tatcttctcg tttaattgcg ccttggcgta agattttcac cttgtctcca
    33421 gacaaatcca caatagttga atcctgtcca gttagaaaag catcgtcttc cagacccaga
    33481 acctcttggt caaaatcctt cagaatttgt tcaaaggtta caccacttgc ctgacctgag
    33541 atattggcag acggcccaat caagggacct gtctctcgaa ttaaatccag tgtgataggg
    33601 tgactgggca tccgaaatcc aatagttgca aggtcagaat ttacccaata gggaactcgg
    33661 tcattggctt cgagaataat ggtcaaggga cctggcaaaa aggtctctac aagtttttgt
    33721 agataagttg gctgattctt agaaaagtgc aagatatcct cgaaagaggc gatattgaga
    33781 ttgagtgcct tatctctagg acgacgtttg agttggtaaa catggtcaac tgctttttca
    33841 tctaaggcct tggcaaaaag accataaaca gtctctgtag gtagaacgac agctccacca
    33901 ttttccaact cttgtctaat cctgtccatc atcaaccaca accatcctat tttgaccaaa
    33961 ttggtctttg agtgttcgaa cttttttttc aggaagatgt tttctaaaaa gttcgggaac
    34021 actttgacct tgcttgtatc caatttcaag gtaaatctta ccaccatcct tgagatagtc
    34081 ttttgcatct tccgcaattc tacagtaaat agctaggcca tcctcgtctg caaagagagc
    34141 tagatgaggc tccgaatgca aaacattcaa acctacctct gactcatctt cacgagagat
    34201 atagggtgga ttggatacaa ttatatcata tttttcagaa atttctgcaa aacaatcaga
    34261 ttttttaaaa aatatattaa gattttgatc gctagcattc tctgatgcaa gctctaaggc
    34321 ctcttgagaa acatctgctg ctgtcactga ccaatctggt ctattttttg ctagagcgag
    34381 agcaatagct ccactacctg ttccaatatc cagaactgag agattcgtct caagattttc
    34441 agttagaata agctccacta actcctctgt ttctggacga ggaatcaaaa cccgttcatc
    34501 cacctttaaa tgcattccat aaaaatctgc ctgtccaatg atgtactgag ctggcttgtg
    34561 agctgctagt tgctggtaaa tatcttctac aaattgtttt tcttcctctg ttgtcacctc
    34621 ctgctggagg gcaaaaataa agtctgtaaa agatagattt ttcagactac gatagacaaa
    34681 agagaggctt tccgcttcct ctccttgtct tatcaactct tcttcaaaat ttgaaaataa
    34741 ttgagctaat ttcattattt gtttaattct tctagttttt gtgtttggtc ataaagcacc
    34801 aaggcatcca caacttcgtc caatttacca gacaaaatcg tatctagttt ttggagggtc
    34861 aagccgatac ggtggtctgt gacacggttt tgtgggaagt tataagttcg gatccgttct
    34921 gaacggtcac cagtaccgat tgtcgactta cgctcagcgt cttgttcatc ctgagcaatc
    34981 tgagcaaagt ggtcagcgac gcgtgcacgg ataatcttca tagccttctc gcggttcttc
    35041 tgctgggtac gttcttcctg catctcaacc ttgatattgg ttggcaagtg aacgatacga
    35101 acggcagtcg caaccttatt gacgttctgt ccaccagcac cagaggcgtg atagatgtcg
    35161 acacgaaggt cttttggatc aatgtcgtat tcaacctctt caacttctgg cataacaaga
    35221 actgtcgctg tcgaagtatg aacacggcct tggctttctg tcacaggaac acgttgcaca
    35281 cggtgggcac ctgattcata cttaagctta gagtatacag actgacctga aaccatagca
    35341 accacttctt taaaaccacc gacaccattc atagaggctt ccatgacttc aaagcgccaa
    35401 ccttgggctt ccgcatactt ttggtacata gttagcaaat ctccagcgaa aagtgccgct
    35461 tcgtctccac cagctgctcc acggatttca aggatgatat tcttgtcatc gtttggatcc
    35521 tttggaagga gcaaaatttt cagtttttct tcatattctt ctttttcagc cttggcatct
    35581 ttgagttctt gcttggccat ttcttccaag tccgcatctc cgcctgattc cttaatcatc
    35641 tcttcggcat cgacgatatt ttgaaggact tgtttatact cacggtaggc tattacggtg
    35701 tcacgattgg aagcttcttc ttttgaaagc tccataaaac gcttggtgtc tgaaacgaca
    35761 tcagggtcac tcagcaattc tcctagttct tcataacggt cttctacagc ttgtagttga
    35821 tcatagatgt tcatttttct tcattctcct tattgatttc aggggcaaaa taatgtttac
    35881 ggcaaaccga gatataggtt tcattaccac caatctggat ctgttctcca tcgtaaacgg
    35941 gcagtccatc ctgtgttcgc aacaccatgg tcgccttttt cttgcaatac tgacagatgg
    36001 tcttgatttc gtcaatcttg tctgctaaaa gcaagagata tttggaacct tcgaacaatt
    36061 cattgcgaaa gtcatttttc aagccaaaag ccatgacggg tatgtctaac tcgtccacaa
    36121 cacgagctag gtcataaaca tggtggcgtt tgagaaactg ggcttcatcg accaaaacac
    36181 agtaaggttt ttctggtagg tctcggatat agccaaagat atccgttgtt tcctcaatcg
    36241 caagggcagg gcgtttcatg ccaattcgac tcgacacata gccaacaccg tcacgcgtat
    36301 ccagagccga ggtcataatc acaacacctt ttccttgctc ctcgtagtta taggccactt
    36361 tgagaatctc aatcgtttta ccagagttca tggtcccata acgatagtac aactgtgcca
    36421 tgtttcttgc ttcacgtcca tttctaaatt tttgctacat tctagtatat cataattttc
    36481 ttaagcttta aacggcaaaa tgtggtaaaa tggaagaaat caaaactagt ggaggaagct
    36541 attatgccat ttgtacgcat cgatttattt gaaggacgca cgctcgagca aaagaaagct
    36601 cttgctaagg aagtaacgga agcggttgtt cgcaacactg gagcacctca atctgctgtt
    36661 catgtcatca tcaacgacat gccagaagga acttatttcc cacaagggga aatgcgcacc
    36721 aaataagcta gcttaagcag aattgcttag gctttttcaa tctccaagta gcacccattg
    36781 aagaaatagt ctaaatttgt tacaatttga aaagagactt ggaaaattcc aagaaaagag
    36841 caattaatta aaggaaacat tatgattaca cgtgaatttg ataccatcgc tgctatctct
    36901 actccactag gtgaaggggc tattggtatt gtccgcctga gcggaacaga cagttttgct
    36961 attgtgcaaa agatttttaa aggaaaagac ttgaacaagg ttgccagcca cactctcaac
    37021 tacggtcaca ttattgatcc tctgactggt aaagtcatgg acgaggttat ggttggggct
    37081 atgaagtctc caaagacctt cactcgtgag gatattatcg agattaacac ccacggtggg
    37141 attgcggtga ccaatgaaat tctccagcta gctattcgtg aaggggctcg gttggcagaa
    37201 cctggtgaat ttaccaaacg tgctttttta aacggtcgcg tagacttgac acaggcagag
    37261 gctgtgatgg atatcatccg tgccaagact gacaaggcca tgaacattgc ggtcaaacaa
    37321 ttagacggct ccctttctga cctcattaac aatacccgtc aagaaatcct caatacactt
    37381 gcccaagttg aggtcaatat cgactatcct gaatatgatg atgttgagga agctactact
    37441 gccgttgtcc gtgagaagac tatggagttt gagcaattgc taaccaatct tcttagaaca
    37501 gcccgtcgcg gcaaaatcct tcgtgaagga atttcaacag ctatcatcgg acgtcccaac
    37561 gttgggaaat ccagccttct caacaacctc ttgcgtgagg acaaggctat cgtaacagat
    37621 atcgctggga caacacgaga tgtcatcgaa gagtacgtca acatcaatgg tgtacctctc
    37681 aaattgattg atacagccgg tattcgtgaa acagatgaca tagtggaaca aatcggtgtt
    37741 gagcgttcga aaaaagccct caaggaagcc gacttggttc tactagtgct aaatgccagt
    37801 gaacaactga ctgcgcaaga cagacaactt cttgaaatta gccaagatac caatcgcatt
    37861 attctactta ataaaaccga cctgccagaa acgattgaaa cttcgaaact acctgaagac
    37921 gttatccgta tttcagtcct taaaaaccaa aacatcgaca agattgaaga gcgaatcaac
    37981 aacctcttct ttgaaaatgc tggcttggtc gagcaagatg ctacttactt gtcaaacgcc
    38041 cgtcacattt ccctgattga aaaagcagtt gaaagcctac aagccgttaa tcaaggtctt
    38101 gagctgggga tgccagttga tttgcttcaa gttgacttga ctcgtacttg ggaaatcctc
    38161 ggagaaatca ctggggatgc tgctccagat gaactcatca cccaactctt tagccaattc
    38221 tgtttaggaa aataagaaaa atccatgatc cttcattcgg tcatggattt tattgtcttt
    38281 attagtaatc tggtcttaag acccctgtta cagttgcctt agttgcttcg tagtcgccat
    38341 ctacgacaac cttgataatg cgtttggcat cttcttctgg tgctggaaca agaggtagac
    38401 gagtgggtcc agcttcaaat cccatatagt taagaattgc cttaactgga gcaggacttg
    38461 gataagagaa gagagcatta accttaggaa tgaatttacg ctgaattgct gcggctttct
    38521 tcatatcgct ttctgcaatg gcagtaaaca tctcgtgcat ttcatcccca tttgtatgag
    38581 aggcaacaga aataacccca tccgccccaa ggttcatggc atggaaagca tctccatcct
    38641 cacctgtata aatcaagaac tcttcaggct tgtgctcaat caagtaagcc atattagcca
    38701 agctagtaca ttctttgaca ccgataatat ttggatggtc agccaagcga agcatggttt
    38761 ctggagtcaa ttcgacaact acacgccctg gaatgttata gataataatt ggtaggtcag
    38821 aagcatctgc aatagcctta aagtgctgat acatcccttc ttgagaaggt ttgttgtagt
    38881 aaggaacaat agcaagccca gctgcgaaac caccaaattc cgctacttct ttgacaaact
    38941 caatagagtc acgcgtatca ttagtaccta cacccgcaat caaaggaacg cgtccattga
    39001 caaccttttg tacagccgca aacaactcca actcctcatc gtgggtcaaa gttggactct
    39061 cagcagtcgt tcctgcgaga agaattccat ccgtatgatg ggccaataaa tgctcaatca
    39121 aggctggaat agcatcaaag ttaatggaac catcctcatg gaagggggta ataaaggctg
    39181 taatgatttt acattctttt aaatcttgat aagacacgaa aacacctctc tatttcaaag
    39241 aaggagttca tctgaactcc taaacgatat gactatttta attcaaattt caattcagct
    39301 gttggacgaa ccaatccacg ttcatgaaga gtttcagcaa tctgaactga gttccaagca
    39361 gcacctttga gaaggttatc tgaaacaacc cacatgtgaa ttcctttttc tgcatccaag
    39421 tctttacgga tacgaccaac aaaggtatca cgtgaaccaa ctgcattgat ggcttgagga
    39481 tagatttgat gaactacatc atcttcaaga acagcacctg ggaaggatgc gatagctgct
    39541 ttgacttctt caattggagc cacttccttt gtttcaatat aaactgactc agagtgagct
    39601 gacaagactg gaatacgcac acatgtcgca gatactgcaa tgctatcatc ttccataatt
    39661 ttcttagttt ccttggtcat cttcatctct tcgtacgtgt aatcattatc agtgaagaca
    39721 tcaatttgtg gaagagcgtt aaaggcgata ggataatgtt tcttgtcacc acctgaaggc
    39781 aagatttccg catgcaaatc acgtggtttc actccatcat tcaagacctc acgaagttca
    39841 cgttgtgtct caagaattgc tcccatacca gcacctgaaa cggcttgata agttgaaaca
    39901 atgatacggt ccaagcccca tttttggcga accggctcaa gagccaccat catttggatt
    39961 gttgaacagt tagggcaggc aatgattccg ttgtgggcat caagtgcatg agcattgacc
    40021 tctggaacaa ccaaaggaac atctggattt tgacggaaat aagatgtatt atccactact
    40081 accacgccag cttttactgc gtatggtgca tacttagctg atgtcgaacc acctgctgaa
    40141 aagagagcaa tatcaactcc ttcaaaagct gtttcagtcg tttcttcaat cgtaatatct
    40201 tgatctttaa atttcaatga cttacctgct gaacgtgcag aagcaaggta acggatttta
    40261 tcgattggaa gtgttgattc ttccaacatt tttatcatct gagcaccgac agcacctgtc
    40321 gcgccgacta cagcaactgt atatcccata aataacctct ttcggaattt tctaaaaatt
    40381 tctataatag aagtattata ctactttttc catgaattgc aaagcttttt catcattttt
    40441 tggaaaataa aaatccccaa tcgctagact agggattaag aggcatcttc atgtgatgag
    40501 caggttcaca caactcatca aggtccgctc ctgcgttatg acctccttat gctcaatagt
    40561 agcccgaaga ctacctatcg actcatcgca tctactattc tactagatag agtcattttt
    40621 gtcaacagcc aaaactcttt atactcttcg aaaatctctt caaacttcgt cagcgtcgcc
    40681 ttgccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa aacatgtttt
    40741 gagctgactt cgtcagtttc atctacaacc tcaaaaacat gttttaagct gacttcgtca
    40801 gttctatcta caacctcaaa gcagtgcttt gagcaacctg cggctagttt cctagtttac
    40861 tctttgattt tcattgagta ttagttttat ttacacaggt gcataagaaa tatattggaa
    40921 aaattggggg cagacataac aaaaaccctt gtaaatcaag ggcttttctg tctatttaat
    40981 gctaattgcc gggattgaac cggcgacctc atccttacca tggatgcgct ctgccaactg
    41041 agctaaatca gcttacttaa gaagtatact atattcagaa aaacttgtca agtttcctta
    41101 gaaattttcc ataggaaaaa gccaggtaag aactacctag cttatcttct tctatttact
    41161 taaatcaatt cgacgaccaa ttttaccaat aataatcgct ccaataatca atgaagcaaa
    41221 ttcaccgatt cctgttgtaa accaagtaag gaagaatggt aattctgcta caatatttaa
    41281 ctctgcagcg atagtaaaca tggaaattga aaagaggatt gaaaagaaga aatgatcttt
    41341 tcgaatcaat ccgttaaaga ggtaatcctt gctatatttt gcaaaaagcc aaacacctaa
    41401 actgaggaat actaaggttg aaccaccacc aacaaagaca tctagcagtc cgaagctaaa
    41461 gaaattagca atcatacaac cgatggtaac tccgatgatg tacttaggat tgtaaaaagc
    41521 cataaagttc atcatttctg aaatacgaaa ctgataagca ccatagctga tggcatttag
    41581 gggcggtgtg acagtcaaaa cgacgtagat agcagcgacg attgcaatat ctgcaacatc
    41641 acgaatagtt aattttttca tcttttctcc tttggcggtt atccgcgtgt aatatgcttg
    41701 gtgaaagaag ctaagcacca agggttgatt cattcaacct tactagtata gcacaatagc
    41761 ctgctttatg ctatacttaa agcatgaaaa aacctattca aaaatttttt aacaatgaaa
    41821 tcttagccta tctctttttt ggccttgcga caactctagt ttcgattctc tcacgactag
    41881 tcatttatca actaagtcat caggaactcc ttgctacggc cttggcaaat attatcggta
    41941 tcttatttgc ctttatcaca aatgatacga ttgtatttaa gcaaaaaaag aaaaatagac
    42001 ttatccgttt agtgaaattt tctcttgctc gcctttctac ttttctgtta gacttgtttt
    42061 taacttttct ctttgtaacc caatttcctc acatcatagg gcaattcgta actgaaaaca
    42121 ttgataagat aaatgctatt gaaacaataa ttgcacaaat attcattatt atcatcaatt
    42181 atatcttgag caaggtctat atttttagaa aataatgctc catttatgag ccttttaatt
    42241 gccttctata atgatttagg atacaatgaa acacgaaaca ttgaaaggaa aacagtatgt
    42301 taaaaaatct aaaatcgttc ttgcttcgag gaaatgttat tgaccttgct gtcggtgttg
    42361 tcattgcctc tgcttttggt gctatcgtta cttcacttgt aaacgacatt atcactcctc
    42421 ttattttaaa tcccgctttg aaagctgcta aagtcgaacg tatcgctcaa ctttcttggc
    42481 atggagtcgg ctatggtaac tttttaagtg ctattatcaa ttttatcttt gtgggtaccg
    42541 ccctcttctt tattatcaag ggcattgaaa aagcacagaa actgactggc ataaagaaag
    42601 aaaaaactgc cgaaaaaaaa ccaaccgaat tggaagtcct tcaagaaata aaagctctcc
    42661 ttgagaaaaa ataatcgatt aaaaggatct agcgcaaagc taaatccttt tttctttact
    42721 ctttgggtaa cttgcctgct ttttcaagca tttttttgat aagataaggc atcttaacat
    42781 tctcccgccc ttttttctca atcagttttt tcacaaattc tggcatttgt aaatcttcag
    42841 attcagctaa aatgtttttc gtctcgtctg aaggaactaa ctcatcaaag gtctcttctt
    42901 ctgggagaaa ttccttaaac tcttgatttt cattgactct aactgtattg accaaagcat
    42961 caatcaaacg agaatctgta tttggcattg gtggacgatg gtagtttacc ccaaattcct
    43021 ggcataagtc ataacattct acatcattgt caaacaagac ctcaatatgc tcactgatga
    43081 aactaatagg tacaaaaata taatggtctg gatgttctgt ctgttctctg agatactcca
    43141 aaacatctgg tttaatccat ggaataccaa tatcactctc actctgccaa gtgttggtat
    43201 attgttctga actcaagccc agtttttcag cgactagctt gctattttcg aaaatttggt
    43261 ctatataagg atcaccaaag tccaaggcaa aaatgggcac actatgggct gaaaagatga
    43321 ctttaaagct gtcttgcttt acttcttctt ttaaaatctt agcaatttca tctgcccaat
    43381 agtttaagag cgcttcttcc tgataccagt ccttaatgac caaaaattga atttgtttgc
    43441 tttctaaaaa tttttcatag cccatgacag agtagaaaga ataatggggc tccaaaatca
    43501 agcaaataca ctgttcaatt ccgtctgctt ccatttgacc gatcacatct ggaataaagg
    43561 gactggaaaa cttattagca aagtagacac tgtattcatt ccccagccta gcttctacca
    43621 aggcaacctc ttgacgggta attttttgca gaggcgtgcc tccaattcgt acataattat
    43681 catagagagt ctgaatctcg tggtcttggg gtctcacccc acgacgaata tttgtgaaaa
    43741 aatcagctac accttcaaag gtaatctctt ctggtgaacc gaaggtcatc attaaaattg
    43801 cttttttcat gactgcttcc ttgtgatgtt tttatcaagt ttattttatc attaattaat
    43861 cgataagtaa acgctaatat agggacattc tcaatcttct gtcttttgtt tttctcttct
    43921 ttctatgata caatggaaaa aataaattca aaaggagttt ttttatgact tatccaaatc
    43981 tcttggaccg cttcttaacc tacgttaagg tcaacacgcg ctctgatgaa cactctacta
    44041 ctactccaag tacacagagt caggttgact tcgcaacaaa tgtcctaatt cctgaaatga
    44101 aacgtgttgg actgcaaaat gtttactatc taccgaatgg ttttgctatt ggaaccttgc
    44161 cagccaacga tccgtcttta acacgtaaga ttggttttat atcgcacatg gatactgctg
    44221 attttaatgc tgaaggagtc aatccacagg taattgaaaa ctacgatggt ggtgtgattg
    44281 aactagggaa ttctggtttc aaactcgatc cagctgactt caagagtctt gaaaaatatc
    44341 caggacaaac gctcatcaca acagatggaa caagcttgct aggtgctgat gacaagtcag
    44401 gaattgctga aattatgaca gccattgaat atctaactgc tcatcctgaa attaagcact
    44461 gtgagattcg tgttggtttt ggtccagatg aagaaatcgg tgttggtgcc aataaatttg
    44521 atgcagaaga ttttgatgtg gattttgcct acactgttga tggtggtcca ctaggtgaac
    44581 ttcagtacga gactttctca gccgctggtg ctgaattgca tttccaaggc cgtaatgtcc
    44641 accctggtac tgccaaagag cagatggtca atgcccttca gctagcaatt gattttcata
    44701 atcaacttcc agaaaatgac cgacctgagt taactgaagg ttaccaaggt ttttaccatc
    44761 taatggatgt gacaggtagt gttgaggagg tgcgtgcaag ctacatcatt cgtgattttg
    44821 aaaaagatgc ctttgaagcg cgtaaagcat ccatgcaatc tatcgctgat aagatgaatg
    44881 cagaacttgg gagctaccgt gtcactctca acttgacaga ccagtactac aatatgaaag
    44941 aagtcattga aaaagatatg actccaatta ccattgctaa agccgttatg gaagatctag
    45001 gtatcacgcc tattatcgaa ccaatccggg gtggaacaga cggctctaag atttccttta
    45061 tgggaatccc aactccgaat atctttgcag gtggcgaaaa tatgcacgga cgttttgaat
    45121 acgttagcct tcagactatg gaacgtgcag ttgataccat cattggcatc gtagcttata
    45181 aaggctaaaa agacgaggta gctcagctac ttcgcctttc tttttattct actggttttt
    45241 cttgatttcc agtagttgta gaagattctg ttgtttcatt ttctgaagtt gattcagcag
    45301 gtttagaatc tcttgtattg cttggtttgt tttcgtcgct agcaatttca atgttagatt
    45361 ctgcagttgc gtttggttgg ttctcagcac tggtgttatc actatttgct tcagcatttc
    45421 ttgctggact tgtttcttca cttgcgctag cttttgactg gatttgatga ttcaaaacta
    45481 gaatagcttt tgtcgattca agtaaagctg ttttgtcttt actcttagca gaaagttgat
    45541 ctaataatgc atccacctta tcaaagtccg catcagatcc attattactt tctaaataag
    45601 agtgaagcga catgagaata tcgtagagtt tttgatagag tacaagtgtc tgagaatctt
    45661 gctcagcatt ttccttttct tgttgaaggg cgctagcgat acgagtcaag acatctttta
    45721 cctgactgtt tacttcatcc aagtctgcat cagccttgtt tgtggcagct tttagatttt
    45781 ctacttcttc tgccaaggat tgtctgattc cttcttcatg gatttgttcc aagagttgat
    45841 ttaccttgct caaaagactt tctacttctt ccttgctatc tgtcgcagat tattggttgc
    45901 catctaccat gtactcctaa aacaggagag ttataatcca agattacaag gccttacaga
    45961 aataagaaat ccagataaga caatgttcgt ccaagacgct attcgcttcg cacagcagca
    46021 cggattcaat atgctttaat tttaaagttt aggtgtcaag acctcttttt agtgtgccca
    46081 aaatttagag aagtaatcaa tcaactaact tttatttttt tcaaactttc agtaaactga
    46141 cctaaagcta actcaatctg tctttgtaga tgcttctgct atcagctaga agttgatcta
    46201 cttttgccaa gactgccttc tcatcaaaag ttccaggttg atagttggat tgcagggatg
    46261 gaatcttgtt tttcaaagcc gcttcatatc ccttagtttg aaccttgatg tagtgattgt
    46321 ggtcgccatg aggaatcaca aaaccttctg aatcttcact tataattcga ttggcatcaa
    46381 aaccatgacc atcttcttcc tcatgatgga catgtagtga cggattactt aatacagaac
    46441 tagaagaact tcctacctct tccgtgttag agtgtgatgg gggattgtta agagatgact
    46501 taggaatata gtgatagtga tccccatgtc ttactatata agcatcacct gtatctctga
    46561 caatatcatt agggttaaag acatatgtgg ctgctaattc acctgccgac aagtcactct
    46621 caggaatgaa atgatagtga ccaccatgtg gtactatagt agattgaaat agaatatgag
    46681 caaattgata aggggatttt aaagtaattt ctaacaatga tttagaaact atgatgtgct
    46741 attctaaatt caactcacta tatataacca tcatcggtag tataacgtcc ctgtaatttt
    46801 gctacagata cttctgcact agctccttta tcgtctttac catgttcttg tttttggcga
    46861 ttgatttcat cttttgttcg tacattttct gcatgagctt gatctttaag gtaaacataa
    46921 tactttccat ctaccttaat aatatatcct cccttaacct aactgacgat atcttgatct
    46981 ttcggctgat agttgggggc tttcattaat agctcttcac taaagagcgc atcaaaagga
    47041 actttaccat tatagtagtg ataatgatcg ccatgagaag ttacataacc ttgatctgta
    47101 atcttaataa caatttgttt tgcttgaatt ccttcttttt gactaaccta gtctggagtc
    47161 aaattttcag tcttcttagt gtctttatta ctgtttacat atgaaacacg atttttatct
    47221 gtattggcct gttagctatg ttggttcaga gcataaacac acagacttaa ggaaaggata
    47281 acaacagatc cagctgctat atatttcttt ttaaatttca taattacctc atttctataa
    47341 t
//
LOCUS       DBEJJV010000013        41161 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.013, whole genome shotgun sequence.
ACCESSION   DBEJJV010000013 DBEJJV010000000
VERSION     DBEJJV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 41161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41161
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.013"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..450
                     /locus_tag="ACL3GT_000829"
     CDS             <1..450
                     /locus_tag="ACL3GT_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516513.1"
                     /translation="LIIYLFLLYLFIDLLMKSGILDEQIDKLSELSNLFTIKIETILT
                     VISVVFTFIATLIEYGFSLFLITLFFDKNKRNFGDILLSKNITLSFSILLCYLFNPSD
                     IKFAYFSVLTVLLIGITNYARFKNLRLTVVFSVPFLFNAIMSIINSF"
     gene            830..2983
                     /gene="comA"
                     /locus_tag="ACL3GT_000830"
     CDS             830..2983
                     /gene="comA"
                     /locus_tag="ACL3GT_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter ComA"
                     /protein_id="HGR0516514.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKANMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLIALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2996..4345
                     /gene="comB"
                     /locus_tag="ACL3GT_000831"
     CDS             2996..4345
                     /gene="comB"
                     /locus_tag="ACL3GT_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence pheromone export protein ComB"
                     /protein_id="HGR0516515.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4515..5222
                     /gene="purC"
                     /locus_tag="ACL3GT_000832"
     CDS             4515..5222
                     /gene="purC"
                     /locus_tag="ACL3GT_000832"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HGR0516516.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            5279..9004
                     /locus_tag="ACL3GT_000833"
     CDS             5279..9004
                     /locus_tag="ACL3GT_000833"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HGR0516517.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITIGIAKQEFS
                     ESDKTIPKLPFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTATHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDINGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANNTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9097..10539
                     /gene="purF"
                     /locus_tag="ACL3GT_000834"
     CDS             9097..10539
                     /gene="purF"
                     /locus_tag="ACL3GT_000834"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HGR0516518.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10576..11598
                     /gene="purM"
                     /locus_tag="ACL3GT_000835"
     CDS             10576..11598
                     /gene="purM"
                     /locus_tag="ACL3GT_000835"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HGR0516519.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11595..12140
                     /gene="purN"
                     /locus_tag="ACL3GT_000836"
     CDS             11595..12140
                     /gene="purN"
                     /locus_tag="ACL3GT_000836"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HGR0516520.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12224..12733
                     /locus_tag="ACL3GT_000837"
     CDS             12224..12733
                     /locus_tag="ACL3GT_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HGR0516521.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12758..14305
                     /gene="purH"
                     /locus_tag="ACL3GT_000838"
     CDS             12758..14305
                     /gene="purH"
                     /locus_tag="ACL3GT_000838"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HGR0516522.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQEFIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14427..15689
                     /gene="purD"
                     /locus_tag="ACL3GT_000839"
     CDS             14427..15689
                     /gene="purD"
                     /locus_tag="ACL3GT_000839"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HGR0516523.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHYKLIDFAKANDIAWTFIGPDDALAAGIVDDFHAAGLKAFGPTRLAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            15946..16062
                     /locus_tag="ACL3GT_000840"
     CDS             15946..16062
                     /locus_tag="ACL3GT_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HGR0516524.1"
                     /translation="MKERLDDNPIVQGNWKTLGFQFRHETPLVAAAVPHKLR"
     gene            16092..16580
                     /gene="purE"
                     /locus_tag="ACL3GT_000841"
     CDS             16092..16580
                     /gene="purE"
                     /locus_tag="ACL3GT_000841"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HGR0516525.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16567..17640
                     /gene="purK"
                     /locus_tag="ACL3GT_000842"
     CDS             16567..17640
                     /gene="purK"
                     /locus_tag="ACL3GT_000842"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HGR0516526.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEKYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLISNEPDSVGEF"
     gene            17663..20050
                     /locus_tag="ACL3GT_000843"
     CDS             17663..20050
                     /locus_tag="ACL3GT_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0516527.1"
                     /translation="MFEKIKGINIKSGIFEDETKLELFEGNFEGTNPVQNDRASLLFG
                     RNGSGKSTIARGINQLKNGEIGTDRVSFIDKNNNNIVLSDTERKSIFVFNEHYVDQKV
                     KIAQEGLDTIVILGEQVDIDEELDRLRTQLSESQIESQDYYAEYEEYLDEKNEKSPDF
                     WKKEMTDSLKGVGNWAERDREIKGNRAASPVHNNTFQNFVDLQPILDKNELEVEFNNK
                     KARYFSIRDSAVTINNELSLPDINFDSNELSTLLSEKIEEPELNSRDKYLLTLLSDST
                     KGERHLREVKDFFEDEHQKKCPFCTQSVSEDVKVELTNGITKLLSRAVEEHQSALRGK
                     KIDEINQDFSGYEQIDPILIQSYQNSINALNAKFNEINSIIDKKIDNPYNIVELPNIS
                     FSQELSQAEHDIEKINQAIIKHNSEISGIQKLKVDLLQINNELAFYEIQDAYKKFQEK
                     TNKKAICENNYNNSSKRVKDYEKQISDLEDKKLNIDIAVDEINKSLNYIFFSKNRLAI
                     QNQNGKYYLLSRGKSVVPSRVSVGERNALALCYFFTEIIQQRELADAYSHEYFIVIDD
                     PISSFDMENKVGITSYLKYCLTRFFKGNSNTRVLLMTHDKQTIYDFDIFLKEIMESCK
                     EEEGGQKSKYKKLELVSGKLQEFKTSTHDYTELLEIVFGYALGNSTPTSESFVGNAMR
                     KILEAYGSFNYKKGIAELTTDPLIVEKIDKEYRTYFENLMYRLVLNGESHFKDPVKTL
                     SIDFFDTISDEERKKTARDLLVLLYLLDDLHVLKHLEGVSNAENRLEQWKCEILE"
     gene            20223..21521
                     /gene="purB"
                     /locus_tag="ACL3GT_000844"
     CDS             20223..21521
                     /gene="purB"
                     /locus_tag="ACL3GT_000844"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HGR0516528.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEINEIFNPIYYTKRVDDIFERLGLGD"
     gene            complement(21576..25514)
                     /gene="strH"
                     /locus_tag="ACL3GT_000845"
     CDS             complement(21576..25514)
                     /gene="strH"
                     /locus_tag="ACL3GT_000845"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored beta-N-acetylhexosaminidase StrH"
                     /protein_id="HGR0516529.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKEEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETETGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLDQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQDEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPRLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(25829..26545)
                     /locus_tag="ACL3GT_000846"
     CDS             complement(25829..26545)
                     /locus_tag="ACL3GT_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0516530.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            26893..28680
                     /locus_tag="ACL3GT_000847"
     CDS             26893..28680
                     /locus_tag="ACL3GT_000847"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HGR0516531.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRIPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLNNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            28677..29153
                     /locus_tag="ACL3GT_000848"
     CDS             28677..29153
                     /locus_tag="ACL3GT_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0516532.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            29181..30086
                     /locus_tag="ACL3GT_000849"
     CDS             29181..30086
                     /locus_tag="ACL3GT_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0516533.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            30073..30888
                     /locus_tag="ACL3GT_000850"
     CDS             30073..30888
                     /locus_tag="ACL3GT_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0516534.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALTLSALGHFALGM"
     gene            30895..31299
                     /locus_tag="ACL3GT_000851"
     CDS             30895..31299
                     /locus_tag="ACL3GT_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0516535.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIGGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            31597..32763
                     /locus_tag="ACL3GT_000852"
     CDS             31597..32763
                     /locus_tag="ACL3GT_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HGR0516536.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKKLVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALDCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            32879..33916
                     /locus_tag="ACL3GT_000853"
     CDS             32879..33916
                     /locus_tag="ACL3GT_000853"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HGR0516537.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            34123..34977
                     /locus_tag="ACL3GT_000854"
     CDS             34123..34977
                     /locus_tag="ACL3GT_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0516538.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            35127..35384
                     /locus_tag="ACL3GT_000855"
     CDS             35127..35384
                     /locus_tag="ACL3GT_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HGR0516539.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADLVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(35426..35743)
                     /locus_tag="ACL3GT_000856"
     CDS             complement(35426..35743)
                     /locus_tag="ACL3GT_000856"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516540.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDRTDEVSNHIYGKVKLTWFEEI
                     FEEYKSPHNKTHTIKVFMYCPPKVRQKKSNFWGQYISIPDTMRFFNFKDFLQLLLTHI
                     KLF"
     gene            complement(35815..36093)
                     /locus_tag="ACL3GT_000857"
     CDS             complement(35815..36093)
                     /locus_tag="ACL3GT_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HGR0516541.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNA"
     gene            36315..37079
                     /locus_tag="ACL3GT_000858"
     CDS             36315..37079
                     /locus_tag="ACL3GT_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HGR0516542.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPCRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(37319..37561)
                     /locus_tag="ACL3GT_000859"
     CDS             complement(37319..37561)
                     /locus_tag="ACL3GT_000859"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516543.1"
                     /translation="MKTKASIRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADKTDEVS
                     SKHCFEVADKTDEVSSKHCFEVADRTDEVSNIYTAR"
     gene            37779..39158
                     /locus_tag="ACL3GT_000860"
     CDS             37779..39158
                     /locus_tag="ACL3GT_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HGR0516544.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            39172..39837
                     /locus_tag="ACL3GT_000861"
     CDS             39172..39837
                     /locus_tag="ACL3GT_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HGR0516545.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            40147..40686
                     /locus_tag="ACL3GT_000862"
     CDS             40147..40686
                     /locus_tag="ACL3GT_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0516546.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQEFESKGQEVDVFVTNFVYEKEGQSCKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YIMMHSLIYRTDLLRASQF"
     gene            40753..>41161
                     /locus_tag="ACL3GT_000863"
     CDS             40753..>41161
                     /locus_tag="ACL3GT_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HGR0516547.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLY
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
BASE COUNT        11552 a         7804 c         9463 g        12342 t
ORIGIN      
        1 ctgattattt atctttttct tttatatttg tttattgatt tactgatgaa gtcgggaatt
       61 ttagatgaac aaattgataa attatctgaa ctatctaatc tttttacaat taaaatagaa
      121 acaatattga cagtgatttc tgttgttttc acatttatag caactcttat tgaatatgga
      181 ttttctctct ttctgattac attatttttt gataagaata agaggaactt tggagatatt
      241 cttttatcta aaaatataac cttaagtttt agcattttac tttgttattt atttaatcca
      301 tcggatataa agtttgccta tttcagcgta ttgacagtat tactaattgg gataacaaat
      361 tatgcgagat ttaaaaattt aagattgaca gtagtgtttt ctgtaccatt tttatttaat
      421 gctataatgt ctattataaa tagtttttag aaatactaaa atttttttct ttacttaata
      481 atgatatgaa atcatttcgg ttttgttaac ttgtaattct tatattttct aggtagaacg
      541 tttgttctgc ctattttttt atccaaaaag tgcagttggg agggagatag gctcatttgg
      601 gaaggaagtc cagtttttgt ttagtgattg gggtaagata gttgttatca gatgagttta
      661 tactcttcga aaatcaaatt caaaccacgt caacgtcgcc ttgccgtata tatgtgactg
      721 acttcgtcag tcctatctac aacctcaaaa cagtgttttg agcagcctgc ggctagtttc
      781 ctagtttgct ctttgatttt cattgagtat tagggaaaag gagatgaata tgaaatttgg
      841 gaaacgtcac tatcgtccgc aagtggatca gatggactgc ggtgtagctt cattagccat
      901 ggtttttggc tactatggta gttattattt tttggctcac ttgcgagaat tggctaagac
      961 gaccatggat gggacgacgg ctttgggctt ggtcaaggtg gcagaggaga ttggttttga
     1021 gacgcgagcc attaaggcga atatgacgct ttttgacttg ccggatttga cttttccttt
     1081 tgttgcccat gtgcttaagg aagggaaatt gctccactac tatgtggtga ctgggcagga
     1141 taaggatagc attcatattg ccgatccaga tcccggggtg aagttgacta aactgccacg
     1201 tgagcgtttt gaggaagaat ggacaggagt gactcttttt atggcaccta gtccagacta
     1261 taagcctcat aaggaacaaa aaaatggtct gctctctttt atccctatat tagtgaagca
     1321 gcgtggcttg attgccaata tcgttttggc aacactcttg gtaaccgtga ttaacattgt
     1381 gggttcttat tatctgcagt ctatcattga tacctatgtg ccagatcaga tgcgttcgac
     1441 actagggatt atttctattg ggctagtcat cgtctacatc ctccagcaaa tcttgtctta
     1501 cgctcaggag tatctcttgc ttgttttggg gcaacgcttg tcgattgacg tgattttgtc
     1561 ctatatcaag catgtttttc acctccctat gtccttcttt gcgacacgca ggacagggga
     1621 gatcgtgtct cgttttacag atgctaacag tatcatcgat gcgctggctt cgaccatcct
     1681 ttcgattttc ctagatgtgt caacggttgt cattatttcc cttgttctat tttcacaaaa
     1741 taccaatctc tttttcatga ctttattggc gcttcctatc tacacagtga ttatctttgc
     1801 ctttatgaag ccgtttgaaa agatgaatcg ggataccatg gaagccaatg cggttctgtc
     1861 ttcttctatc attgaggaca tcaacggtat tgagactatc aagtccttga ccagtgaaag
     1921 tcagcgttac caaaaaattg acaaggaatt tgtggattat ctgaagaaat cctttaccta
     1981 tagtcgagca gagagtcagc aaaaggctct gaaaaaggtt gcccatctct tgcttaatgt
     2041 cggcattctc tggatggggg ctgttctggt catggatggc aagatgagtt tggggcagtt
     2101 gattacctat aataccttgc tggtttactt taccaatcct ttggaaaata tcatcaatct
     2161 gcaaaccaag cttcagacag cgcaggttgc caataaccgt ctaaatgaag tgtatctagt
     2221 agcttctgag tttgaggaga agaaaacagt tgaggatttg agcttgatga agggagatat
     2281 gaccttcaag caggttcatt acaagtatgg ctatggtcga gacgtcttgt cggatatcaa
     2341 tttaaccgtt ccccaagggt ctaaggtggc ttttgtgggg atttcagggt caggtaagac
     2401 gactttggcc aagatgatgg ttaattttta cgacccaagt caaggggaga ttagtctggg
     2461 tggtgtcaat ctcaatcaga ttgataaaaa agccctgcgc cagtacatca actatctgcc
     2521 tcaacagccc tatgtcttta acggaacgat tttggagaat cttcttttgg gagccaagga
     2581 ggggacgaca caggaagata tcttacgggc ggtcgaattg gcagagattc gagaggatat
     2641 cgagcgcatg ccactgaatt atcagacaga attgacttcg gatggggcag ggatttcagg
     2701 tggtcaacgt cagagaatcg ctttggcgcg tgctctcttg acagatgcgc cggtcttgat
     2761 tttggatgag gcgactagca gtttggatat tttgacagag aagcggattg tcgataatct
     2821 cattgctttg gacaagacct tgattttcat tgctcaccgc ttgactattg ctgagcggac
     2881 agagaaggtg gttgtcttgg atcagggcaa gattgtcgaa gaaggaaagc atgctgattt
     2941 gcttgcacag ggaggctttt acgcccattt ggtcaatagc tagaaagagg agaggatgaa
     3001 accagaattt ttagaaagtg cggagtttta taatcgtcgt taccataatt tttccagtag
     3061 tgtgattgta cccatggccc ttttgctcgt gtttttactt ggctttgcaa ctgttgcaga
     3121 gaaggagatg agtttgtcca ctagagctac tgtcgaaccc agtcgtatcc ttgcaaatat
     3181 ccagtcaact agcaacaatc gtattcttgt caatcatttg gaagaaaata agctggttaa
     3241 gaagggggat cttttggttc aataccaaga aggggcagag ggtgtccaag cggagtccta
     3301 tgccagtcag ttggacatgc taaaggatca aaaaaagcaa ttggagtatc tgcaaaagag
     3361 cctgcaagaa ggggagaacc actttccaga ggaggataag tttggctacc aagccacctt
     3421 tcgcgactac atcagtcaag caggcagtct tagggctagt acatcgcaac aaaatgagac
     3481 catcgcgtcc cagaatgcag cagctagcca aacccaagcc gaaatcggca acctcatcag
     3541 tcaaacagag gctaaaattc gcgattacca gacagctaag tcagctattg aaacaggtac
     3601 ttccttggcc ggtcagaatc tagcctactc tctttaccag tcctacaagt ctcagggcga
     3661 ggaaaatccc caaactaagg ttcaggcagt tgcacaggtt gaagcacaga tttctcagtt
     3721 agaatctagt cttgctactt accgtgtcca gtatgcaggt tcaggtaccc agcaagccta
     3781 tgcgtcaggg ttaagcagtc aattggaatc ccttaaatcc caacacttgg caaaggttgg
     3841 tcaggaattg acccttctag cccagaaaat cttggaggca gagtcaggta agaaggtaca
     3901 gggaaatctt ttagacaagg ggaaaattac ggcaagtgag gatggggtgc ttcatcttaa
     3961 tcctgagacc agtgattcta gcatggttgc agaaggtgcc ctactagccc aactttatcc
     4021 atctttggaa agagaaggga aagccaaact cacagcctat ctaagttcaa aagatgtagc
     4081 aagaatcaag gtcggtgatt ctgttcgcta tactacgact catgatgccg ggaatcaact
     4141 ttttctagat tctactatta caagtattga tgcgacagct actaagactg agaaagggaa
     4201 tttctttaaa atcgaggcgg agactaatct aacttcggag caggctgaaa aacttaggta
     4261 cggggtggaa ggccgtctac agatgattac gggcaagaaa agttatctac gttattattt
     4321 ggatcaattt ttgaacaaag agtaatgttc gtgtttttag agttaaataa tttttaaact
     4381 gtgagaaaga ttcttcttgc agttttttct ttacaatttt tgaaaaacat ctgctattta
     4441 ttcggttaaa ttcttgtgtt ttttggtttt ttgtggtaaa atgtgctcaa gtaatacgaa
     4501 aggcgaactt taaaatgtca aaacaattga tctattcggg aaaagctaaa gatatctata
     4561 caactgagga tgaaaatctt attatttcaa cttacaagga ccaggcgact gctttcaatg
     4621 gtgtcaagaa ggagcagatt gcaggtaagg gagtcttgaa taatcagatt tcatctttta
     4681 tttttgagaa attaaatgcg gctggtgtgg cgactcactt tgtggagaaa ctttcagaca
     4741 cggaacaact caataaaaag gttaagatta ttcctttgga agtcgtgctc cgcaactata
     4801 ctgctggttc cttttcaaaa cgttttggtg tggatgaggg aatcgccttg gagactccga
     4861 ttgtcgaatt ttactacaaa aatgatgatt tggatgatcc atttatcaat gatgagcatg
     4921 taaaattcct acagattgcg gatgaccagc agattgccta cttgaaggaa gaaacgcgtc
     4981 gtatcaatga actattgaaa gtctggtttg ctgagattgg gcttaaattg attgacttta
     5041 agctagagtt cggttttgac aaggatggca agattatctt ggcagacgaa ttttcaccag
     5101 ataactgccg cttgtgggat gctgatggca accacatgga taaggatgtt ttccgtagag
     5161 gattgggaga actaaccgac gtttatgaga ttgtttggga aaagttgcag ggtttaaaat
     5221 aacaacctca aggctgtttg ggaatattgc aagagctgaa ataaaggaat aagaattgat
     5281 ggataaacgt atttttgttg aaaaaaaggc tgattttcag gtcaagtcag agagtttggt
     5341 tagagagctc cagcacaact tgggactgtc aagcttgaaa agtattcgta ttgtgcaagt
     5401 atatgatgta tttgacttgg ttgaggactt gtttgcacct gcagagaagc acattttctc
     5461 tgagcaggta accgaccatg ttttagatga agtatctgtg caggcggatc ttgctaacta
     5521 tgctttcttt gccattgaaa gtctaccagg gcagtttgac cagcgtgcag cttcgtcaca
     5581 ggaagccttg cttttgttgg gaagttcgag tgacgtgaca gtcaacacag cccaacttta
     5641 cttggtgaat aaagatattg atgcgactga gttggaagct gtcaaaaact acctgctcaa
     5701 tccagttgat tctcgtttca aggatatcac gatagggatt gccaagcagg agttttcaga
     5761 gtcagacaag accattccaa aattgccttt ctttgaaagc tatacagcag aagactttgc
     5821 tcgctacaag gccgaacaag ggatggccat ggaagtggat gatttgctct ttatccaaga
     5881 ctactttaag tcaatcgggc gcgtgccaac tgagactgaa ctcaaggttt tggacactta
     5941 ctggtctgac cactgccgtc atacgacttt tgagacagag ttgaaacaca tcgacttttc
     6001 agcttctaaa tttcaaaagc aattgcagtc aacctatgac aagtatattg ccatgcgcga
     6061 ggaattaggt cggtctgaaa aaccacaaac cttgatggat atggcgacta ttttcggtcg
     6121 ttatgagcgt gctaatggac gattggatga tatggaagtc tctgacgaaa tcaatgcctg
     6181 ctcagttgaa attgaagtgg acgttgatgg tgtcaaggaa ccttggctcc tcatgtttaa
     6241 aaacgaaact cacaaccatc caacagaaat tgagccattt ggtggagcgg ctacctgtat
     6301 cggtggagct attcgtgatc cgttgtcagg ccgttcctat gtttaccaag ccatgcgtat
     6361 ttcaggtgct ggtgatatta cagcaccgat ttcggaaact cgtgctggga aattgccaca
     6421 acaagtcatt tctaaaacag caactcatgg ttattcttca tatggtaacc agattgggct
     6481 tgccacaacc tacgttcgtg aatacttcca cccaggcttt gtagctaaac gtatggaact
     6541 tggtgccgtt gttggtgcgg ctcccaaggg caatgttgtc cgtgaaaaac ctgaagcagg
     6601 tgatgtgatc atccttctcg gaggtaaaac aggtcgtgat ggtgtcggtg gtgcgacggg
     6661 ctcttctaag gttcaaacag ttgagtctgt agagactgct ggtgctgagg ttcaaaaagg
     6721 aaatgccatc gaagaacgca agattcagcg cctcttccgt aatggcaatg tcactcgtct
     6781 gatcaagaag tccaatgact ttggggcagg cggtgtctgt gtggctatcg gtgaattggc
     6841 agacggtctt gaaatcgacc tcaacaaggt gcctcttaaa taccagggct tgaatggtac
     6901 agaaattgcc atctctgaat cacaagaacg gatggcggtc gtggttcgtc ctgaagatgt
     6961 ggataccttc gttgccgaat gtaacaaaga aaatattgat gctgttgtgg tggcgacagt
     7021 aactgaaaaa ccaaatcttg tcatgcactg gaatggtgag acaatcgttg acttggagcg
     7081 tcgtttcctt gacatcaatg gtgtgcgcgt ggttgtcgat gccaaagttg tggacaagga
     7141 tgtcaaactc ccagaagagc gtcaaacatc tgctgaaaca ctggaatcag atacccttac
     7201 ggttctatct gacctcaacc atgcaagtca aaaaggatta cagactatct ttgactgctc
     7261 tgttggacgc tcaacggtta atcacccact tggtggtcgt taccaactca caccaactga
     7321 ggcatctgtg cagaaattgc cagttcaaca cggtgtgact catactgcgt cggtcattgc
     7381 tcaaggtttc aacccatatg tagctgaatg gtctccatac cacggtgctg cttatgcggt
     7441 tatcgaagca actgctcgtt tggtggctgc tggtgccaac tggtccaagg ctcgtttctc
     7501 ttaccaagaa tatttcgagc gtatggacaa gcaagcagag cgttttggtc agccagtagc
     7561 cgctcttcta ggctctattg aagctcagat tcaacttggc ttgccatcta tcggtggtaa
     7621 ggactccatg tctggtacct ttgaagaatt gaccgttccg ccaaccttgg ttgcctttgg
     7681 ggtgacgacg gcagatagcc gtaaggtgct ctctccagaa tttaaagctg ttggggaaaa
     7741 tatctactac atcccaggtc aagccctctc tgcagagatt gattttgact tgattaagaa
     7801 aaattttgct cagtttgaag caagccaagc tgaccataaa gtgacatctg catcagctgt
     7861 caaatacggt ggtgtagttg aaagtttggc tcttgctacc tttggaaact atattggtgc
     7921 agaggtgacc ttgcctgaac ttaaaacagc tttgacagct caattaggcg gctttgtctt
     7981 cacatctcct gaagaaattg ctggagtaga gaagattgga caaacgaaag cagactttac
     8041 actgactgtc aacggtgtga agctagatgg acacaagctt gacagtgcat ttcaagggac
     8101 attggaagaa gtttacccaa cagaatttac ccaagcgaaa gaactagaag aagtaccagc
     8161 tgtggcatca gatgttgtga ttaaagccaa agaaaaggtt gaaaaacctg tggtttacat
     8221 cccagtcttt ccaggaacca actcagaata tgattcagct aaggccttcg aaaaagaagg
     8281 tgcagaggtc aatttggtgc cattcgtgac cttgaatgaa gaagctattg tcaagtcagt
     8341 tgaaactatg gttgacaata tcgacaagac taatattctc ttctttgctg gtggattctc
     8401 ggctgcggat gaaccagatg gttcagctaa gtttatcgtc aatatcctgc ttaatgaaaa
     8461 agtgcgtgtg gctattgata gctttatcgc ccgtggtggt ttgattatcg gtatttgtaa
     8521 tggattccaa gccttagtca aatcgggtct cctaccctac ggaaactttg aagatgctaa
     8581 caatactagc ccaaccctct tctacaatga tgccaaccaa cacgtggcca agatggtgga
     8641 aactcgcatt gccaatacca actcaccatg gttggctggt gtgcaagtgg gcgatatcca
     8701 cgctattcct gtttcgcacg gtgaagggaa gtttgtcgtg acggctgagg aatttgcaga
     8761 gctccgtgac aatggacaaa ttttcagcca atacgttgac tttaacggta aaccaagtat
     8821 ggattctaag tacaatccga atggttctgt ccatgccatc gaaggaatta ccagcaagaa
     8881 tggtcaaatc atcggtaaga tgggccactc agaacgttat gaggatggtc ttttccaaaa
     8941 tatcccaggc aataaagacc aacacctgtt cgcatcagcg gttaaacatt tcactggaaa
     9001 ataagactta cagattttct aatagatagt atcagtaatg taaaagtcat gtaaatctag
     9061 ctcttgatga ttacaaatga aaattaggta taaaaaatga catacgaagt aaaatctctt
     9121 aatgaagaat gtggtgtttt cggtatttgg ggacatccag atgctgctaa gttgacctat
     9181 tttggactcc acagtcttca acaccgtggt caggaggggg caggaatcct ctccaatgat
     9241 caaggacaac tgaagcgcca tcgtgacatg gggcttttat cagaagtttt cagaaatcca
     9301 gccaatttgg ataaattgac aggagctggt gcgattgggc atgtgcgtta tgcgactgct
     9361 ggcgaagctt ctgttgataa catccagccc ttcctcttcc gttttcacga tatgcagttt
     9421 ggcttggctc ataatggaaa tctgaccaat gcagcctctc tcaagaaaga actggaacaa
     9481 agaggagcaa ttttcagcgc gacttcggac tctgaaatct tggctcacct cattcgtcgc
     9541 agtcataatc ctagcctgat gggcaaaatc aaggaagcgc tcagccttgt caaaggtggt
     9601 tttgcctata tcttgctgtt tgaggacaag ttgattgcgg ctcttgaccc taatggcttt
     9661 cgtccgcttt ctatcgggaa aatggccaac ggagcggtgg ttgtttcctc tgaaacctgt
     9721 gcttttgagg tcattggtgc cgagtggatt cgtgatttga agccaggtga gattgtgatc
     9781 attgatgacg agggcattca gtatgacagc tatacagatg atactcagtt ggcgatttgt
     9841 tctatggagt atatctactt tgctcgccct gattctaata tccacggtgt caatgtccat
     9901 acggcacgta agagaatggg agcgcaattg gcgcgagaat ttaagcatga ggcagatatt
     9961 gtagttggtg tgcccaattc ttccctaagc gcggctatgg gatttgcgga agaatcaggc
    10021 ttaccaaatg aaatgggtct gatcaaaaac caatacaccc agcgaacttt tatccaaccg
    10081 actcaagaat tgcgggagca aggagtgcgg atgaaactgt ctgctgtttc gggtgttgtc
    10141 aaaggcaaac gtgtggtcat ggtggatgat tccattgtac gtggaacaac ctctcgtcgt
    10201 atcgttcagc tcttgaaaga agcgggtgcg actgaggttc acgttgccat tggaagtcct
    10261 gcactagcgt atccatgttt ctacgggatt gatatccaga cccgtcagga gctgattgca
    10321 gccaatcata cggtcgaaga aactcgccaa atcattggtg cggacagtct gacttatctt
    10381 tcaattgatg gcttgattga gtcgattggt atcgaaacag atgcgccgaa cggtggtctc
    10441 tgtgtcgctt actttgacgg tgactaccca acgcctctct atgactacga agaagactat
    10501 cgtagaagtt tggaagaaaa gaccagtttt tacaagtagg cgacagattc tccattaaag
    10561 aaaaggaaaa aacaaatgac aaataaaaat gcatatgccc agtcgggtgt ggatgttgaa
    10621 gcgggttatg aagttgttga acggattaaa aagcacgtgg cccgtacgga gcgtgcaggt
    10681 gtcatgggag ctcttggtgg ctttggtggt atgtttgacc tttccaagac tggggttaaa
    10741 gaacccgtct tgatttcagg gactgacggt gtcggaacca agctcatgtt ggctatcaag
    10801 tacgacaagc acgataccat cgggcaggac tgtgtggcca tgtgtgtcaa cgacatcatt
    10861 gctgcaggtg cggaacccct ctattttctc gactacgtag cgacagggaa gaatgaacca
    10921 gctaagctag aacaagtggt tgctggtgtg gcagaaggtt gtgtgcaggc tggtgctgcc
    10981 ctcatcggtg gggaaacggc tgaaatgccg ggcatgtacg gcgaagacga ctatgacttg
    11041 gctggttttg cggtcggtgt ggctgaaaaa tctcaaatca ttgacggttc aaaggtggta
    11101 gagggagatg ttcttctcgg acttgcttca agtgggattc actcaaatgg ttactctttg
    11161 gttcgtcgtg tctttgcgga ttacacaggt gaggaagtcc taccagaatt ggaaggcaag
    11221 aaacttaagg aagttctact tgagccgact cgtatctatg tcaaggctgt cttgccgctc
    11281 atcaaagaag agttggtcaa cggcattgcc cacatcacag gtggtggctt tatcgaaaat
    11341 gtccctcgta tgtttgcaga tgacctagct gctgaaattg atgaaagcaa agttccagtg
    11401 cttccaattt tcaaagccct tgaaaaatat ggtcagatta aacacgaaga aatgtttgaa
    11461 atcttcaata tgggtgtggg acttatgttg gcggtcagcc ctgaaaatgt agagcgtgta
    11521 aaagaattgt tggatgaagc agtctatgaa attggtcgca tcgtcaagaa agaaaacgaa
    11581 agtgtcatta tcaaatgaaa aaaatagcgg tttttgcctc tggtaatggc tcaaattttc
    11641 aggtgattgc cgaagaattt ccagtggagt ttgtcttttc agaccatcgt gatgcctatg
    11701 tgcttgagcg tgcaaagcag ctcggcgttc tgtcctatgc ttttgaactc aaggagtttg
    11761 agagcaagac agactacgaa gcagcccttg tcgaactctt ggaagaacac cagattgact
    11821 tggtttgcct agcaggctac atgaaaatcg ttggaccaac cttattgtcg gcttatgaag
    11881 gtcggattgt caacattcat ccagcctact tgccagaatt tccaggagct catgggattg
    11941 aggatgcttg gaatgctggc gtgggtcagt ctggtgtgac cattcactgg gtggattcgg
    12001 gtgtggatac aggccaggtc atcaaacagg ttcgtgtgcc acgactagct gatgatacca
    12061 ttgacagatt tgaagctcgc atccatgaag cagagtacag gttgtatccg gaagtagtga
    12121 aggctctatt tacagattga ctttttgatg attcatatga tatctttgat tttaaattgg
    12181 agtcagtgtt tgttgaagac ggcttcaaac ggaggtattt gtaatgttag aatctaaaaa
    12241 aacaactcga tatgtatttt atgtctatct gatgttatta acttggggaa tcttatttaa
    12301 gtttgaaaca aatcctgaat ttatagcatt tttcttagct ccaaggtata tcaattggat
    12361 tccattttca gaaccactaa tagtcgatgg aaaaattgtt tttgctgaaa tgttatttaa
    12421 tctgatttcc tttattccat taggtgtttg tttccctttg ataaaaacta atttatctag
    12481 tttaagaata gtcgggacag gtttcttgat tagtttattg tttgagtgct tacagtatat
    12541 tttagcaata ggtataacag atataacgga tttgacttta aatacgctag gtgtctgtgt
    12601 aggcttactg atttatcaaa tttttataag agtgttcaaa tcacagacta gaaaatggat
    12661 caatatctta ggtatgctta gccttggttt tgcttatctt gttttactgt tactgcattt
    12721 aattggtgtt taactaatga ttaaaaagga gaatataatg actaaacgcg tcttaatcag
    12781 cgtctcagac aaagcgggca ttgttgaatt tgcccaagaa ctcaaaaaac ttggttggga
    12841 gattatctca acaggtggaa ctaaggttgc ccttgataat gctggggtgg ataccattgc
    12901 tatcgatgat gtgactggtt tcccagaaat gatggacggt cgtgtgaaga ccctccaccc
    12961 aaatatccac ggagggcttc tcgctcgtcg tgacttggat agccacttgg aagcggctaa
    13021 ggacaacaag attgagctca ttgaccttgt ggtggtcaac ctttacccat ttaaggaaac
    13081 tatccttaaa ccagatgtga cttatgctga tgcagttgaa aatatcgata ttggtgggcc
    13141 gtctatgctt cgttcagcag cgaaaaatca tgccagtgtt acagttgtgg tagatcctgc
    13201 tgactacgct gtggttttgg acgaattggc agcaaacggc gaaacctctt atgaaactcg
    13261 ccaacgttta gcagccaaag tatttcgtca cacagcggct tatgacgcct tgattgcaga
    13321 atacttcaca gctcaagtgg gtgaaagcaa gcctgaaaaa ctcactttga cttatgacct
    13381 caagcaacca atgcgttacg gtgagaatcc tcaacaagac gcggactttt accagaaagc
    13441 tttgcctaca gattactcta ttgcttcagc caaacagctc aacgggaaag aattgtcatt
    13501 taataatatc cgtgatgcag atgctgctat ccgtatcatc cgtgacttca aagatagtcc
    13561 aaccgttgtg gctctcaaac acatgaatcc atgtggaatt ggtcaagctg atgacatcga
    13621 gactgcttgg gactacgctt atgagtctga cccagtatct atctttggtg ggattgtcgt
    13681 cctcaaccgt gaggtggatg ctgcgacagc tgagaagatg cacggcgttt tcctcgaaat
    13741 catcattgca ccaagctata cggatgaagc gctagctatt ttgatcaata aaaagaaaaa
    13801 cttgcgtatc cttgccttgc catttaatgc tcaagaggct agcgaagtgg aagcagaata
    13861 cacaggtgta gtcggtggac ttctcgtgca aaatcaagac gtggtcaagg aaagcccagc
    13921 tgactggcaa gtggtgacca aacgtcagcc aactgagaca gaagcgactg ctcttgagtt
    13981 cgcttggaag gctatcaagt acgtcaaatc aaatggtatt atcgtgacca acgaccacat
    14041 gacacttggt gttggtccag gtcaaaccaa ccgtgtggct tctgttcgcc ttgccattga
    14101 ccaagccaaa gatcgtctga acggggcggt ccttgcttca gatgccttct tcccatttgc
    14161 ggataacgtg gaagaaatcg ccaaagcagg aattaaggcc atcatccagc ccggtggctc
    14221 tgtccgtgac caagaattca tcgaagcagc ggataaatac ggcttgacta tggtctttac
    14281 aggtgtgaga cattttagac attaagaaga taaaagggaa gaaaacagtt tctttccttt
    14341 tttggcttaa aatgctaact gaaacaagat taaaacgaac ttttttgata taatgttggt
    14401 aaataattcg caaaagaggt tgaggaatga aactgcttgt tgtcggttct ggtggtcgtg
    14461 agcatgcgat tgctaaaaag ttacttgaat caaaagacgt ggaaaaagtc tttgtagctc
    14521 ctgggaatga cggtatgact ctggatggtc tggaattggt aaatatatct atttccgaac
    14581 attataaatt gattgacttc gcaaaggcca acgatattgc ttggaccttt atcggtccag
    14641 atgacgccct tgcggctggt atcgtggatg atttccatgc agctggtctc aaagcctttg
    14701 gtccgacaag attggcagcg gagctggagt ggtccaagga tttcgccaag gaaatcatgg
    14761 tcaaatatgg tgtttcgaca gcagcctatg gcacattttc agatttcgag gaagcaaagg
    14821 cctatatcga aaagcatggt gcgcctatcg tagtcaaggc ggatggcttg gcgcttggga
    14881 agggtgtcgt cgttgctgag acggttgagc aagcggtcga agccgctcat gagatgcttt
    14941 tggacaataa atttggtgac tcaggtgcgc gcgtggttat tgaggaattc cttgaaggag
    15001 aggaattttc actctttgcc tttgtcaatg gtgataagtt ctacatcatg ccaacggctc
    15061 aggaccacaa acgtgcctac gatggcgaca aagggcctaa cacgggtggt atgggtgcct
    15121 atgcgccagt tccacactta ccacagagtg tagttgatac agcggttgac accattgtca
    15181 agccagttct agaagggatg attaaagaag gtcgccctta tctgggagtt ctttacgcag
    15241 ggcttatcct gacagctgat ggaccgaaag tcattgagtt caacgctcgg ttcggagatc
    15301 cagaaactca gattatcttg cctcgcttga cctctgactt tgctcaaaat atcacagata
    15361 tcctggatag caaggagcca aatatcatgt ggacggacaa gggtgtgact ctgggtgtgg
    15421 ttgtcgcatc caagggctac ccgctagact atgaaagggg cgttgagttg ccagccaaga
    15481 cagaaggcga tgtcatcacc tactatgcag gggctaagtt tgcggaaaat agcagagcac
    15541 tgctctcaaa cggcggacga gtttatatgc tcgttaccac agcagatacc gtcaaagaag
    15601 cccaagccag catctaccaa gaactatccc aacaaaaaat agaaggactc ttctaccgaa
    15661 cagatatcgg aagcaaggca attaagtaaa gatataagaa taacgcgccg tagtcgccaa
    15721 acacgataat ggtcgtcgtg gtgaaaagac cagaacagtg aatgttctgg tcagggggaa
    15781 acttggagac cgtaggctca aagtttagga atgaaaccga aggtttgctt ccgcctccat
    15841 cacctaagac cattatcaaa aagaaaaata aaaattcaca aaatacgtta atgatcgtat
    15901 ggtttgcgag cgttagcgag ctaatataga acaatcaccg ccgttgtgaa agaacgattg
    15961 gatgataatc caatcgttca gggaaattgg aagaccttgg gtttccaatt taggcatgag
    16021 acacctttgg tggctgctgc cgtccctcac aagctaaggt gattgttgaa aaagaggaaa
    16081 aaggagaaga aatgaaacca gtaatttcca tcatcatggg ctcaaaatcc gactgggcaa
    16141 ccatgcaaaa aacagcagaa gtcctagacc gcttcggtgt agcctacgaa aagaaagttg
    16201 tttccgcaca ccgtacacca gacctcatgt tcaaacatgc agaagaagcc cgtagtcgtg
    16261 gcatcaagat catcatcgca ggtgctggtg gcgcagcgca tttgccaggc atggtagctg
    16321 ccaaaacaac ccttccagtc attggtgtgc cagtcaagtc tcgtgctctt agtggagtgg
    16381 attcactcta ttctatcgtt cagatgccgg gtggggtgcc tgttgcgacc atggctatcg
    16441 gtgaagctgg agcgactaac gcagctctct ttgccctccg tctcctctct gtagaagata
    16501 agtccattgc ggatgcactt gccaactttg ctgaagaaca aggaaaaatc gcagaggagt
    16561 cgtcaaatga gctcatctaa aacaatcgga attatcggtg gcggtcaact gggtcagatg
    16621 atggccattt ctgctatcta catgggccac aaggttatcg cgctggatcc tgcggcggat
    16681 tgcccggcct ctcgcgtggc ggaaatcatt gtggcacctt ataacgatgt ggacgccctc
    16741 cgtcagttgg cagaccgttg cgatgtcctc acttatgagt ttgaaaatgt cgacgctgac
    16801 ggtttggatg ccgttatcaa ggatggacaa ctccctcaag gaacagatct gctccgcatt
    16861 tcgcaaaatc gtatttttga aaaggacttt ttgtcaaaca aggctcaagt cactgtggca
    16921 ccctacaagg tcgtgacttc tagcctagac ttggcagata tcgacttgtc gaaaaactat
    16981 gtcctcaaga ctgcgactgg tggctacgat ggtcatggac aaaaggttat tcgttcagaa
    17041 gcagacttgg aagcagccta tgcgctagca gactcagcag actgcgtctt ggaagaattt
    17101 gtcaactttg accttgagat ttctgtcatc gtgtcaggaa atggcaagga ggtgacgttt
    17161 ttcccagttc aggaaaatat ccaccgcaac aatatcctgt ctaagaccat cgtaccagcc
    17221 cgcatttctg aaagtctagt agacaaggct aaagctatgg cagtgcgaat cgcagaacaa
    17281 ctcaacttgt ctggaactct ctgtgtggaa atgtttgcga ctgatgatga cgttattgtc
    17341 aatgaaatcg ccccacgacc acataactct gggcactatt ctattgaagc ctgtgatttc
    17401 tctcagtttg acacccatat tctcggtgtt ctcggagcac cattaccagt catcaaactc
    17461 catgcgcctg ccgtcatgct taacgttctc ggccagcatg ttgaggccgc tgaaaaatat
    17521 gtcacagaaa attcaagcgc ccacctccac atgtatggta aaatagaagc gaagcacaac
    17581 cgcaagatgg gacatgtgac tttgattagt aatgaaccag atagtgtggg agagttttag
    17641 gggagagggg tctaaagaaa aaatgtttga aaaaattaaa ggaattaata taaaatcagg
    17701 tatttttgaa gatgaaacaa aattagaact ctttgaagga aattttgagg gaacaaatcc
    17761 agtacaaaac gatagggcaa gtttattgtt tggaaggaat ggttcaggga aaagtaccat
    17821 tgctcgagga ataaatcaat taaaaaatgg tgagattgga acagatagag tatcatttat
    17881 tgataaaaat aataataata ttgtacttag tgatactgaa cgaaaatcga tatttgtttt
    17941 caatgaacac tatgttgatc agaaagtcaa aattgctcaa gaagggttag atacaattgt
    18001 aattttaggt gaacaggttg atatcgatga ggaactggat agattaagaa cgcagttatc
    18061 agaatcacaa attgaatctc aagattatta tgctgaatat gaagaatatt tagatgaaaa
    18121 aaatgaaaaa tctccagatt tttggaaaaa ggaaatgaca gattctttga aaggagtagg
    18181 caactgggcc gaaagagata gggagataaa aggaaatcga gctgcatctc ccgttcataa
    18241 taataccttt caaaattttg ttgatttaca accaatctta gataaaaatg agttagaggt
    18301 tgaattcaac aataaaaaag ctagatattt ttcaataaga gattccgcag ttactataaa
    18361 taatgaacta tctttacctg atattaattt tgatagcaat gaattatcaa ctttattgtc
    18421 tgaaaaaatc gaagaacctg agttgaattc tagggataag tatttactga cattattatc
    18481 tgattccaca aaaggtgaac gtcatttgag agaagttaaa gatttctttg aagatgaaca
    18541 tcaaaaaaaa tgtcctttct gtactcaatc agtatcagaa gatgttaaag ttgaactcac
    18601 gaatggcata actaaactac tatcaagagc agtcgaagaa caccaatccg cattgagagg
    18661 taaaaaaatt gatgagatta atcaagattt ttctggttat gaacagatag atccaatatt
    18721 aattcagtct tatcaaaata gtattaatgc tttgaatgct aaatttaacg aaattaactc
    18781 aataatcgat aagaagattg ataatccata taatatagtt gagttaccta atataagctt
    18841 ttctcaagaa ttaagtcaag cagagcatga tattgaaaaa attaaccaag caattatcaa
    18901 acataattca gaaatctcgg gtattcaaaa gttaaaagta gatctccttc aaataaataa
    18961 tgaattagct ttttatgaaa ttcaagatgc atacaaaaag tttcaagaga aaacaaataa
    19021 aaaagcaatt tgtgaaaata attataataa cagtagtaaa cgagtaaagg attatgagaa
    19081 gcagatttct gatttagaag acaagaaact taatatagat attgcagttg atgaaattaa
    19141 taaaagttta aattacatat ttttttcaaa aaatcggtta gctatacaga atcaaaacgg
    19201 aaaatactat ctgttatcaa gaggtaagtc tgtggtcccc agtagggttt ccgtagggga
    19261 acgaaatgcg ctggcattat gttatttctt tactgagata attcaacaga gagagttagc
    19321 agatgcttat agtcatgaat attttattgt tattgacgat ccaatttcta gttttgatat
    19381 ggaaaataaa gttggaataa cctcgtattt aaaatattgt ttaactagat tttttaaggg
    19441 gaatagtaat actagagttt tactaatgac ccatgataaa caaacaatat atgactttga
    19501 tatctttttg aaagagataa tggaatcctg taaagaagag gaaggtggac aaaaatctaa
    19561 atacaagaag ttagaattgg tttctggtaa attacaagaa ttcaaaacta gtactcacga
    19621 ttatacagaa ctacttgaaa tagtcttcgg ttatgcattg ggaaatagta cacctacttc
    19681 ggaaagtttt gttgggaatg caatgagaaa aattttagaa gcctatggta gttttaatta
    19741 taagaaggga attgccgagc taacaacaga tcctttaatt gttgaaaaaa ttgataaaga
    19801 atacagaact tattttgaga atcttatgta tagactggtt ttaaacggtg aaagtcattt
    19861 taaggatccg gttaaaactt tgagtattga tttctttgat accatttctg atgaagaacg
    19921 aaaaaaaaca gctagagatt tactagtttt gctttatctt ttagatgatt tacatgtttt
    19981 aaaacattta gagggtgtat caaatgcgga aaatagactt gaacaatgga agtgtgagat
    20041 tttagaataa gagaatcata ccatttgact tattgcaatg gttgaagttt gcatgatagc
    20101 tgattagagt aatcaaagga ttattacttc ctaattttat tttctacaaa ccctaattta
    20161 gcatctaata atgcaaagtt tcctgagcct catagataaa aaagattttt aaggagaaaa
    20221 acatgatcaa ccgttactct cgccctgaga tggcgaatat ttggagtgaa gaaaataaat
    20281 accgtgcttg gcttgaggtg gaaatcctct ctgacgaggc atgggctgag ttgggggaaa
    20341 tccctaagga agatgtggct ttgattcgca agaaggcgga ctttgacatc gaccgtattt
    20401 tggaaattga gcaggagacg cgccacgatg tggtggcttt cacgcgtgcg gtttctgaga
    20461 ctcttggtga agagcgcaag tgggttcact atgggttaac ttctaccgac gtggtggata
    20521 ctgcctatgg ttacctctac aagcaggcca acgacatcat ccgtcgtgac cttgaaaact
    20581 tcactaatat catcgctgac aaggccaagg agcacaagtt caccatcatg atggggcgta
    20641 ctcatggtgt gcacgctgag ccgacaactt ttggtcttaa attggcaact tggtatagcg
    20701 aaatgaaacg caatatcgag cgcttcgagc atgcggctgc tggtgtagaa gctggtaaga
    20761 tttctggtgc ggttgggaac tttgccaata tcccaccatt tgtagaggag tatgtctgcg
    20821 ataaacttgg catccgtgcc caagaaatct ctacacaagt ccttcctcgt gaccttcacg
    20881 ctgagtactt tgcggttctt gccagcattg cgacttcaat cgaacgtatg gcgactgaga
    20941 ttcgtggtct acaaaaatct gagcaacgcg aagtagaaga gttctttgct aaagggcaaa
    21001 aagggtcttc agcaatgcct cacaaacgca acccaatcgg ttctgaaaat atgactggtc
    21061 tggcgcgtgt cattcgtggt cacatgatta cggcttatga aaacgtcgct ctctggcacg
    21121 aacgcgatat ttctcactca tcagctgagc gtatcatcac accagatacg accattttga
    21181 ttgactacat gctcaaccgt tttggaaata tcgtcaagaa cttgacagtc ttcccagaaa
    21241 atatgatccg aaacatgaac tcgacttttg gtcttatctt tagccaacgg gctatgttga
    21301 cattgattga aaaaggcatg acccgtgagc aagcctatga cttggtgcaa ccaaaaacag
    21361 cctactcttg ggacaaccaa gtagacttta aaccacttct tgaggcagat tcagaagtaa
    21421 catcacgtct cacacaagaa gaaatcaatg aaatcttcaa cccaatttat tacaccaaac
    21481 gagtggatga tatctttgaa cgtcttggac taggtgatta attaaaaaat aaacagcgag
    21541 cttcaatctc gctgtttatt ttttatcgaa aagacttagt cttcttttct tttagtgagt
    21601 ccataggctg ctagtgtgga catgagtcct gcgactacta gtcctgcaga atcgtgagtt
    21661 cctgtttcag gaagtttttt ctctgttacc acaggagctg gatcttgagg aagagctttg
    21721 ctttcctcag caggagcagt tgatggagct ggttggcttg ggatttctag tcttggtttt
    21781 tcttcagcaa tagcggcttg tccgttttca tcgcctacat gtgttaccat agttccgact
    21841 tcgactattt gagtaacggc ttcctgtgct acgacactat ttacaagtgt tttcacttcc
    21901 ttaccatcgg cagaagtgct cacagagtag aagttgctac gatgtccatt gacgccctta
    21961 gtaatgactt gtgtttttcc tttgagtaag agtggatttt cacgagtcac tgtggtaaat
    22021 ggaatttctt ctttttggat atccagtcta ggttttacct cagtagttgg tgcaagacca
    22081 ctttcatcac ccttgtgagt tacaggagcg ccaacttcaa ccacttggtt tataacttct
    22141 ttggttacct ggctatcaag gactgtttct gttgtttttc cattttcagt gagtacagag
    22201 atgtaatgag ttcgttcacc tttgactcct gctgtgataa tattttcctg accagctggg
    22261 aggttaggat tttctttctt gataacttca aatggaattt cttcagttct tgtgatgagt
    22321 tctggtctgg tttcaacatt ggcagccact tcattttcat ccaggcttcc tgaatgagtt
    22381 gcagctggtt tgaggccttg aagagcggct tttaggttgg ctacaagtgt gtcaagctca
    22441 gcttgtttat tacggttgag gttgtaattt agagctgttt tagctgcgtc aagggcctca
    22501 agactttctt tactatatcc ttctaagttt gtaggaattt tagctaattc ttcgcggaga
    22561 gcattataat tagcacggaa gtagtctttg ttgtggtctg caaaggcagt catgagttca
    22621 aagatttcct cttccttgta ctcagcgctt ggtctatctg cccagattga aagcatactt
    22681 ccgactgttg gaagatctac ttcaggatat ttggtagaag ctagttgatt gaatggaact
    22741 ttaccagaat tttcaactgc ttttgaaaga gggtaagctt catcttgttt gtgattgcct
    22801 ataacataat accagtcacc gttggtattc aagaatttat agcctttgct tgctaggtat
    22861 tgaggtgatg cgaggttata tccccaccag cctttagacc agtaagaaat caagacatct
    22921 ttgtcaaact gaacatcgtc cttgtcttca tagtagaagc catcgttgaa ggccattggt
    22981 tgaagccctc tttctttggc catagctgcg agggtgttgg catattcggc aaatttgcca
    23041 tagagttgat accacttgag gtagtaccag ccttgggcac tagtcgcatc gttggcgtat
    23101 tcgtcagtac caaagttgaa aatctttgtt ttacctgcaa agaagtccat gtatttaccg
    23161 atgagggctt ttacaaagtt catcgcttct tcgtttttca agtccatagt tgtttttgaa
    23221 actttatcaa agtgggcttg aggattttta atacctaatt tttccatggc aaccagcata
    23281 gcatccatgt gacctggact gttaatagct gggatgagac caatgtcctt agatttagcg
    23341 tattcaatta gctctgtcac ttctgcctgt gttagtgcag taccgtttgg atcgtcgtag
    23401 taagctttag ttccttcgat aatagctttt ttaacgtcat cactagcata ggtttttccg
    23461 ttggcagtaa tggtcatatc attgagtaga aagcgaagtc cgtcatttcc tagaaggaga
    23521 tggacatcag aatatccgag ctcactggcc ttgtctacga tgcgtttgag ctggtccaga
    23581 gtaaagtatt tgcgtccagc atcgattgag attaccttgt ttttggcaag tttttcaacc
    23641 tcacgtttag cttcttcttc tttttgagct tcaggcgtga gggtcaagtt gttgacagtt
    23701 tcttgaagtt tagcaatggc ttgatcaatc gtatcttgtt gggcacggct aaggttgcta
    23761 tcgagagagc gaatagcttt ttcagcttct tttacggccg tgacgctttc tgcagtataa
    23821 cggttcaggt cttttggtac ctcgttaagt gcttgctctg cagattcata atcagctgcg
    23881 aagtattcag cgttggcatt tgcaaaatga cgcatgagtt tgaagaggcg tgatggtgaa
    23941 taacgtgcag atggagtgtc agcccaagca gctaccatac caccgatgat tgggatatca
    24001 gctccttctg tttttggtac agaagtgatt ggtgtgtttt taataccatt gagcccctga
    24061 tcgagattgt accagccttg gccatcagcg tttcgtccaa gaacgtagta ccaagcatca
    24121 ttggtattaa ggatttggtg acctttttca gctagtagtt tagaagaagc gacatcgtag
    24181 cctccccaac caccagtcca catagaaacg atgatgtctt tgtcaaaact accaaagctt
    24241 gtgtcgctat tgtagtagat accgtcgtta aaggccattg gtttgagacc gtgcgatttt
    24301 acaatacgag cgaggtcatt ggcgtaggca ataaattttt catagccttt tacagggtag
    24361 ccttcgtttg gatagtattt atcagcttga agcacactcc aacctttagc atctgtcgca
    24421 tcattggcat attcatcaag tccgatgttg aagatttcag tctttttcgc gaaataagca
    24481 gcatacttgt cgataagggc ttttgtaaaa gcgacagctt gttcgttgtc aagatcgaca
    24541 gtacgggctg atttcttccc aaaatagcta aagttagggt tttggattcc caattctttc
    24601 atggcattga gaatcgcatc catgtgtcca ggactattta ctgtcggaat gagaccgata
    24661 cctttatctt tggcatagtt aatcagatct gtcatttgac tttctgttaa gtgattgccg
    24721 tttggatcgt tgtaataatc atttgtacct ttttcaatgg cgcgtttgac atcgtcactg
    24781 gcataggtct tgccgttagc tgtgatgctc atatcgtcca acatgaaacg gagtccatca
    24841 tttccgacta ataggtgtaa atcagtgtag ccataatgtt tcgctttatc gatgatttcc
    24901 ttgagctgtt ctggtgagaa atatttacgt ccagcatcaa tagaaacaat tttctttttc
    24961 gctagttttt catttacagt tgcagcacgt tcctttcctg tctctgtttc cggtttgtca
    25021 gcctctgctt tcgcttcatc ttttttagct ggtttatcct tgtcagtctt gtctgtattt
    25081 gactctttag aatcaacctc tttcgcttct tcctttttag ggctagcttc ttcttccttt
    25141 ttattagcag tttctttttc agcagaagtt ggagttacca cctctgcttt atcactagga
    25201 gttgaactaa cttcctcttg tggtttttct tctgtttttg gaagactagc taccttatca
    25261 gtagctggag tttctgtttc tacagttttt ggagcttctg gttgaagctc tgctttaggt
    25321 gtttcctcag tccgattttc ggatgattga ggggaatcag aaaccgtatg gatggtcggt
    25381 tggttttctg tagtagtagg agtaactcca tcggctgcaa cagtctgtgc ttggaaggca
    25441 aatccaatta gaacagaagc tgctcctaca gcgtatttac gaatagaaaa acgctgttgt
    25501 ttttcatgtt tcattgcaaa acctcctgat tgcattgtta tattgatagc gattatataa
    25561 atcaacgcct ttattttatt tcttatatta acgagagtca agaggagatg acaaaaaact
    25621 ataataagta taaaaaaata taaaatttaa acttaagatt tcagattggt cgaaaaaata
    25681 catatatata tctagtataa tttttggttc tatttctata aaatattcca caaattatag
    25741 aatcttccaa aaataggtaa gcgctacctt tttggtgtgg tataataagc atagaaaaag
    25801 cccgagcgat taggctcagg ctttcttctt agtgatcacg gtcacatgag atgaatttaa
    25861 tcttgtagta atcagatcgt ttgtaagttt cactgtattc taaaacttgg ccagttgatt
    25921 cgagtttggt gattttagtt tgtaggacag tagggaattg ttcatcgact ccgaggactg
    25981 aagccgcatg ttctggagtt ggaaagacta tttcgttgat ttcttcaaag tgttcatcat
    26041 tcatgtgaat gtggtagtct aacttgaaac gattatagat agaactatag tattcaaggt
    26101 ttggataatt tgcgttgata tattgttctg ggatgtagga tgtatggtag atataaacga
    26161 caccgtttga ttcgcggata cgttcaatct tgtagtagaa ttgatcgccg cgtagaccca
    26221 atttttccaa gtaaacaagc ttgtttccgc gttcaattga aagaacagtt accttatcat
    26281 ctttagcatt gaagagttca atatctgaaa actctacaag cttgtgtttg cgtgcacgtg
    26341 aaacgaaggt tccttttcct tgttggcgga caatatagcc atctttggca aggtcgttta
    26401 aggcgcgaac aactgtgata gagctgacat cgtacattga aatgagttct gcttcagtgt
    26461 aaaatttatc tccactgcta aactgcccag agatgatttt attttttaat tcgtctttta
    26521 tgtattgata tttgggaatt gccatatttt tacctctatt ttccttctcc atagaaaatt
    26581 ttaccataaa agcgaaaaaa atagtagtct tttgaataaa aaattagaat aatagtttga
    26641 aaaattaagc gatataggga ttgctcatat tttatcaatg cattctatac aaaattattt
    26701 taggtcctat attccgaatt taaagagcgt ttgaaatggg tctaaaaatg tttgaaacta
    26761 attgaatgtg tgtataatag taaaaatgca gtaaatatcc cgacaatttc tattgacaat
    26821 tcaaacagat tggtttataa ttaatataac aacaaatgaa agcgcaaact ttcgcggtcg
    26881 gaaggtagtt ttatgacacg atttgagata cgagatgatt tctatctcga tggaaaatca
    26941 tttaagattt tatctggtgc cattcattat tttaggattc ctccagagga ttggtatcat
    27001 tcgctctata acttgaaggc tcttggtttt aatacggtag agacttatgt tgcttggaat
    27061 ttacacgagc ctcgtgaagg tgagtttcat tttgaaggtg atctggattt agagaaattt
    27121 ctccaaatag cgcaggattt gggtctctac gcaattgtgc gtccgtctcc atttatctgt
    27181 gcggaatggg aattcggtgg cttaccagct tggctcttga ccaagaacat gcgaattcgc
    27241 tcatccgacc cagcatatat cgaggcagtt ggtcgctact atgatcagtt attgccaaga
    27301 ctggtgcctc gtttgttgaa caatggtggc aatattctca tgatgcaggt tgaaaatgag
    27361 tatggttctt acggagaaga taaggcttac ctgagagcga ttcgacagct aatggaagag
    27421 tgtggcgtaa cctgtcccct ctttacatca gatggtccat ggcgagctac tctgaaagct
    27481 ggaaccttaa ttgaagagga cctctttgta acaggaaact ttggttctaa ggcaccttac
    27541 aacttttcgc agatgcagga attctttgat gaacatggta agaaatggcc actcatgtgt
    27601 atggagttct gggatggttg gttcaatcgc tggaaagaac cgattatcac acgggatcct
    27661 aaggaattgg cagatgcagt tcgagaggtt ttggaacaag gctctatcaa tctttacatg
    27721 ttccacggtg gtacaaactt tggtttcatg aatggttgct cagctcgagg aactttggac
    27781 ctgccacaag ttacatctta tgattacgat gcccttctgg atgaagaagg aaatccaact
    27841 gctaaatatc ttgcagtcaa gaagatgatg gcaacacatt tttcagagta tccgcagttg
    27901 gaaccactct acaaagagag tatggagttg gatgctattc cactagttga aaaagtttct
    27961 ttgtttgaaa ccttagatag cttgtcaagt cctgtagaaa gtctctatcc tcaaaagatg
    28021 gaggagctgg gacaaagtta tggctaccta ctttatcgaa cagaaacaaa ctgggatgca
    28081 gaagaagaaa gacttcgtat cattgatggt cgagataggg cccagctgta tgtcgatggt
    28141 cagtgggtta aaactcaata tcagacagag attggggaag atatttttta tcaaggtaaa
    28201 aagaaagggc tatctaggtt agatatcttg atagaaaata tggggcgtgt caactatggg
    28261 cataagttct tagcggatac gcaacgtaag ggaattcgga caggggtctg taaggatctg
    28321 catttcttac taaactggaa acactatcca ctcccactag acaatcctga gaaaattgat
    28381 ttttcaaaag gatggactca aggacaacca gccttttacg cttatgactt tacagtcgaa
    28441 gagccaaaag atacttacct agacttgtct gagtttggta agggagttgc ctttgtcaat
    28501 gggcagaatc taggacgttt ttggaacgtt ggcccaactc tctcacttta tatccctcat
    28561 agctatctca aggaaggtgc caaccgtatc attatctttg aaacagaagg tcaatataaa
    28621 gaagagattc atttaactcg taaacctaca ctaaaacata taaaggggga aaacttatga
    28681 caattgtagg atgccgtatt gatggacgtt tgatccacgg acaagtagcc aatctttggg
    28741 ctggaaaact aaatgtttca cgcattatgg ttgtagacga cgaagttgtc aacaacgata
    28801 ttgaaaagag tggtttgaaa cttgcgacac caccaggtgt gaaattgagt attttgccag
    28861 ttgagaaagc tgcagccaat attcttgctg gtaaatacga tagccaacgt ctctttatcg
    28921 tggctcgtaa accagaccgc ttccttggtt tggtagaagc aggtgtacca cttgaaaccc
    28981 ttaatgttgg gaatatgtct caaacaccag aaactcgttc tattacacgt tctatcaacg
    29041 tagtagacaa ggatgtggaa gacttccaca aactggcaga aaaaggtgtt aaacttactg
    29101 ctcagatggt tccaaatgat ccaatttcag actttttgag cttattaaaa taggaaaaaa
    29161 atttttagga ggtcattgtt atgatacaat ggtggcaaat tttacttctc actttgtact
    29221 cagcttatca aatctgtgat gagttgacga tcgtttcatc tgcaggttcc cctgtatttg
    29281 ctggtttcat tactggttta atcatgggag atgtgactac tggtttactt atcggtggta
    29341 acttgcaact gttcgttctt ggggttggta ccttcggtgg tgcttctcgt atcgacgcaa
    29401 cttctggtgc ggttcttgcg acagccttct ctgtttcaca aggaattgat gcaccgcttg
    29461 ccattactac aatcgctgta ccagtagcag ctctcttgac ttacttcgac gttcttggtc
    29521 gtatgactac taccttcttc gctcaccgtg tggatgctgc aatcgaacgc tttgactata
    29581 aaggtattga acgcaactac ttgcttggtg cgattccgtg ggctctatct cgtgcccttc
    29641 cagtcttctt tgcccttgct tttggtggtg cctttgtaca atcagtagta gacttcgttg
    29701 aagcctacaa atgggttgca gatggcttga cacttgcagg acgtatgctt ccaggtcttg
    29761 gatttgcaat cttgcttcgt taccttccag ttaaacgtaa ccttcactac cttgctatgg
    29821 gatttggttt gacagctatg ttgactgttc tttactcata tgtaacaggt cttggtggcg
    29881 ctgttgctgg tatcgtaggt actcttcctg ctgaagttgc tgaaaaaatt ggtttcgtga
    29941 acaacttcaa aggtttgtct atgattggta tttctatcgt aggtattttc cttgcagtgc
    30001 ttcacttcaa aaatagccaa aaagtagctg tagcagcacc ttctacacca tcagaaagtg
    30061 gggaaatcga agatgacgaa ttctaattac aaacttacaa aagaagattt taatcaaatc
    30121 aacaaacgta gcttgtttac tttccaatta ggttggaact acgaacgtat gcaagcttct
    30181 ggttaccttt acatgatctt gcctcagttg cgtaaaatgt atggtgatgg aactcctgaa
    30241 ttgaaagaaa tgatgaaagt tcatactcaa ttcttcaata cttcaccatt cttccatacc
    30301 attatcgctg gttttgacct tgccatggaa gaaaaagatg gtgtaggttc aaaagacgct
    30361 gttaacggta tcaagacagg tttgatggga ccattcgctc ctcttgggga tacaatcttt
    30421 ggttcacttg tacctgctat catggggtca gtcgcagcaa ctatggctat cgctggccaa
    30481 ccttggggga tcttcctttg gattgcagtt gcagtagcgt atgacatctt ccgttggaaa
    30541 cagttggaat ttgcttacaa agaaggggtt aaccttatca acaacatgca aagtaccttg
    30601 acagctttga ttgacgctgc atctgtactt ggtgtcttca tgatgggtgc tcttgtagca
    30661 acagtgatta actttgaaat ttcttacaag ttgccaatcg gtgaaaagat gattgatttc
    30721 caagacatct tgaaccaaat cttcccacgt ttgcttccag caatctttac tgcctttatc
    30781 ttctggttgc ttggtaagaa aggtatgaac tctactaaag ctatcggtat tattatcgta
    30841 cttgctttga ctctttctgc ccttggtcac tttgcacttg gaatgtaatt ccttatgact
    30901 aaatcattaa ttttggtgag ccatggtcgc ttctgtgagg agcttagagg tagcacagaa
    30961 atgattatgg gcccacaaga caacatttac acagtagctc ttcttccaga agatggccca
    31021 gaagaattta ctgctaaatt tgaagctgtt attggaggat tggatgattt cctagtcttt
    31081 gcggatcttc tcggtgggac accttgtaat gtggtgagtc gcttgatcat ggaaggtcgt
    31141 gatattgacc tttacgcagg gatgaatctt ccaatggtga ttgaatttat caatgcgagc
    31201 cttacaggcg cagatgcgga ctacaagagc cgtgctgcag aaagcattgt gaaagttaat
    31261 gacctgttag cgggcttcga tgatgacgaa gatgaataat actcttcgaa aatctcttca
    31321 aactacgtca acgtcgcctt gccgtaggta tatgttactg acttcgtcag tcttatccgg
    31381 caacctcaaa acggtgtttt gagctgactt cgtcagttct atctgcaacc tcaaagtagt
    31441 gctttgagca gcctgcggct agtttcctac agattttagt tggaactcga ttcaattcat
    31501 gtgacaacgt gaaaatcgtt agagcatttt atatagaata tacatgggaa tggagcttac
    31561 tcccattccc atatttaata gaaaaagagg aactcaatgc tacattatac aaaagaagac
    31621 ttgctcgaat tgggtgcaga aatcactacg cgtgaaatct accaacaacc tgatgtatgg
    31681 agagaagctt ttgaatttta tcaagcaaaa cgtgaagaaa ttgcagcctt cctacaagaa
    31741 atcgctgata aacatgacta tattaaggtt atcttgacag gtgctgggac ttctgcttat
    31801 gtgggagaca ccttgctacc ttactttaag gaagtctatg acgaacgcaa atggaatttc
    31861 aatgctattg cgacaacaga tatcgttgcc aatccagcaa cctatttgaa aaaagatgtg
    31921 gcaactgtcc ttgtgtcttt tgctcgtagt gggaactcgc ctgaaagtgt ggcgactgtt
    31981 gatttggcca aatccttggt ggatgagctt tatcaagtga cgattacttg tgcagcagat
    32041 ggtaaattgg ctcttcaagc tcacggtgat gaccgtaatc tcttgctctt gcaaccagct
    32101 gtctctaatg atgctggatt tgccatgact tctagcttta cgtctatgat gttgacagct
    32161 ctcttggtct ttgatcctac agaatttgct gttaagtctg aacgttttga agttgtatct
    32221 agtcttgccc gtaaagtttt agacaaggca gaagatgtca aaaagctcgt tgatttagac
    32281 tttaaccgtg tcatctatct aggcgctggt cctttctttg gacttgctca tgaagctcag
    32341 ctcaagattt tggaattaac tgctggtcaa gttgcgacca tgtatgaaag cccagttggc
    32401 ttccgtcacg gtccaaaatc tcttatcaac gacaatacag ttgttttggt ctttggtaca
    32461 acgacagact acactcgtaa gtacgacttg gacttggttc gtgaagttgc tggtgaccag
    32521 attgctcgtc gtgttgtgct tttgagtgat caagcttttg gtcttgaaaa tgtcaaagaa
    32581 gtggcccttg attgtggcgg tgtcttgaat gatatttacc gtgtcttccc ttacatcgtt
    32641 tatgcccaac tctttgccct attgacttca ctcaaggtag aaaataaacc agatacaccg
    32701 tctcctacag gtacagtaaa ccgtgtagta caaggtgtca taattcacga atatcaaaag
    32761 taagacagtg tttatgaatt cttgacaaga ggatttgtaa attatcagat aaaccataga
    32821 ttgtcagtac gctttctatg gtttgtttgc ttgagagaaa tagtaaaagg agaacagaat
    32881 gaaagcatac acagagcgtg tatttggaaa tgttgagggc gaggatgtct tggcctatcg
    32941 atttgagaca gacggtggct accaacttga ggttatgact tatggcgcga ccatcttgcg
    33001 ctatgtcgca cctgacaagg ctggaaattt tgccaatgtt atcttgggat ttgatgactt
    33061 tgatagttat gtaggcaata gtcccaagca tggagcaagt gtaggtcctg tagcgggtcg
    33121 tattgcaggt gcgacctttg agctcaatgg taagacctat gaccttgagg ttaataatgc
    33181 tagcaactgt aatcacagtg gttcaactgg ttgggattcc agcttgtttg aagttgaaga
    33241 agtaagcgat catggcttga ctctctacac agagcgtaca gatgggacag gagggttccc
    33301 tggaaatctc aagatttgga tcagttatca cttggaagaa actggtgcct atgaaatcag
    33361 ctacaaggta acgaccgatc aggatacgct ggtcaatcca accaaccaca gctatttcaa
    33421 cttgtctggt gatttcacgc agacgattga ccgtcatgtc ttccaactaa acacagaggg
    33481 catttactca atcgctcctg acggtgttcc tgccaaaact ccagaagcca accgtgatgt
    33541 ggtcaaacac atctacaatg gtgccttgtt gaaggatatc tttgcagaag aagatgagca
    33601 aatccagctg gcatcaggtt tggatcatcc atttgccctt cctgcaggcc atgacaatgc
    33661 tggattcctt tatgaccaaa attcaggtcg cttcctgctt ttcaagacag aagctccttg
    33721 ctttgtggtc tacacagcaa actttgtgga tgaaagtgtc atcataggag gtcagccaat
    33781 gctacagcac aatgggattg ctcttgaagc gcaagcttta ccagatgcca ttcacagtga
    33841 ccttaaaggc caagtcattc ttaaagctgg tcaaaccttc accagtaaga cacgttatga
    33901 acttgttgtg aaataaaaaa gctggtcaaa aagtctttaa aattaaaata acgcatattg
    33961 tcaggtgatg aaaagtttga taatatgcgt tttattatga aatgatttac tttatattat
    34021 cctgaaatgg tgttattttt gagttatctg gcttgacttt cttgatggaa attatataat
    34081 agttgcaaca ataataatta caacgaaaaa agaggaccat ttatgaccta tgaatacaag
    34141 agtcacattt atttggcaga gacagtttta aatgtaaagg atttggccag tcaaacagcc
    34201 ttttatcagc aagttatcgg tttagaaatc ttatctcaaa ctgagacaga gtccattcta
    34261 ggccttggtg gaaaagtctt ggtacagctg attcaagcac aagagagcgg agaagtgagg
    34321 gaacattatg gtctttacca tttggccatt ctcttgccca cacgcaaggc tttggctgat
    34381 gtcttgaaac acctgacaga tttacagatt cctcttgtcg gcggtgcaga ccatggttac
    34441 agtgaagcta tttacttgga agatttggag ggaaatggca ttgaactcta tcgagataag
    34501 ccagtttcca catgggatat tcgagaagat ggacgcatta tcggagtgac ggaggctctt
    34561 gcggcgcagg acatttatga gttgggggaa agagtagagc cctttatcct ggcagaaggt
    34621 acgagaatgg ggcatattca tctttcagtc aaggatagtc gaaagtccag ccagttttat
    34681 caaaaggtgt tagggctaga ggataaattc agtgtgccta gcgctagttg gattgcggct
    34741 ggagattacc atcatcattt agcagttaac gaatggggag gaaaaggtct ggcttcgcgt
    34801 aagcaaggct taccaggttt agcctactat gtcatcgaag tcgcacataa aaaagaactg
    34861 ttaacgattg cccaacgagc acaagaagtt gacgcaccaa tcaaatggat gacatcgagc
    34921 caattggaaa tcacagactc agatggcatc gtgacccgta ttcgtttagc aaggtaaaat
    34981 taggaatttt taataagtta taagtattgc tagtttgctt tttgaacggt ctttggtaac
    35041 agaactgcgt gagctggatg ggtgagaatt ttgacaaaga agctgattag agatataatg
    35101 aagaaaagtc gagcaaggaa aaagaaatga caaattcaaa gtatattact tgtttgaaac
    35161 gttcagaggg ccagttgtgt gggattcaaa agatgattga aggagatcgt gactgtgctg
    35221 atcttgtgac gcaactgaca gcagtgagat ctagtgtaga gcgcgtgatt gagatgataa
    35281 ttaccgaaaa tcttactgaa tgtatcaatc agccactaga tgattctgaa gctcaaaagg
    35341 aacgcttaga aaaggctatc cgatacttga ttaaacggaa ataaatgaat gttttgagac
    35401 gatatgtgca aaggtctatt aactattaga atagtttaat gtgagtcaaa agaagttgta
    35461 aaaaatcttt aaaattaaaa aaacgcatag tatcaggtat tgaaatgtac tgcccccaaa
    35521 agttagattt tttctgtcta acttttgggg ggcagtacat aaaaaccttg atagtatgcg
    35581 ttttattgtg gggagattta tactcttcga aaatctcttc aaaccacgtc agcttcacct
    35641 tgccgtagat atggttactg acttcgtcag ttctatccac aaccttaaaa cagtgttttg
    35701 agcagcctgc ggctaacttc ctagtttgca ctttaatttt cattgagtat tacttcatct
    35761 tctcatgaaa ttgagttttt gcccagctcc tcttgattat tctacttgac cgggctaagc
    35821 attcatacca ccttctacgt tggtaacggt gaggccttgg gagctgagaa attggcaggt
    35881 agatgcagag cggactcctc cttgacaaat aacatagtat tcatggtcag gtttgagttc
    35941 tttgtagcct tgctctaagg tacttaatgg aagatttttg gcacctggtg catgtcctgc
    36001 ttggaattca tgtgcttcac ggacatcgat aagttctaga ttttcatttt gatattttcc
    36061 ataaaagtca gccatgctga tactagtttc catattctac tccttctggg ttagccattt
    36121 tgtatagtga ataagcgccg tcaaggtttt ggacggtaaa tcctgcttgc ttgaggatag
    36181 gctctgcgat atagctgcgc aaactactgt ggcaactgac gatgtaggct tgtttttctc
    36241 ctcagttcat cagcttcctc cttgacactc ggtcagattt tgatacaata gtacaaaatt
    36301 agaggaggtg ggctatgatt cagaaacatg cgattcccat tttagagttt gatgataatc
    36361 ctcaggcggt tatcatgccc aatcacgagg ggttggattt gcagttgcca aagaagtgtg
    36421 tctatgcttt tttaggtgag gagattgacc gctatgcgag ggaagtaggg gcgaactgtg
    36481 ttggcgaatt cgtttctgct accaagacct atccagtcta tgtcatcaac tacaagggtg
    36541 aggaggtctg tctggctcag gctcctgttg gctccgctcc agcagcccag tttatggatt
    36601 ggttgattgg ctatggtgtg gagcagatta tctctactgg gacctgtggt gtcctagctg
    36661 atatagagga aaatgccttt ctagtccctg ttcgcgcttt gcgagatgag ggagccagtt
    36721 accactatgt ggcaccttgt cgttatatgg aaatgcagcc agaggctatt gctgctattg
    36781 aggaagtttt ggaagacaga gggattcctt atgaagaagt catgacctgg acgacagacg
    36841 gtttttaccg agaaacggct gaaaaggtgg cttatcgtaa ggaagaaggc tgtgctgttg
    36901 tggagatgga gtgttctgct cttgctgcag tagctcaatt gcgtggggtt ctctggggtg
    36961 aattgttgtt cacagcagat tctctagcgg acttggacca gtacgacagt cgtgactggg
    37021 gctcggaagc ttttaataag gcgctagaac tgagtttagc aagtgttcac cacctttagt
    37081 tgtactggca aaggatttgt tttatcataa aatgtctagc tcatactttt caaaaatatg
    37141 tttaaacgag gtcaccttcc tcttgtccta ggcatgttga ggttgggaaa aatctttaaa
    37201 atcagaaaaa cgtatcatat caggtgatga aaattttgat actatgcgtt ttatgttggt
    37261 aagatttaga gtgagatgaa atgatactct tcgaaaatct cttcaaacca ggtcagcttc
    37321 accttgccgt atagatgtta ctgacttcgt cagttctatc tgcaacctca aaacagtgtt
    37381 ttgagctgac ttcgtcagtt ttatctgcaa cctcaaaaca gtgttttgag ctgacttcgt
    37441 cagttttatc tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtt ctatccacaa
    37501 cctcaaaaca gtgttttgag caacctgtga ctagctttct aatcgatgcc ttggttttca
    37561 ttgcctataa tcaaaaagag aaattttctc ctgaaaagca tatagagtag ctggcgttaa
    37621 aagctcctgt cttgcttttt tgacctatag tcatatctat caagtattgt tcttgcctaa
    37681 gctatcaata aaaaggtggc attttttagg cttggtgtta gtgaattttg ccttatccta
    37741 tctaagtcat ttcgagcttt ttatggtaca atggaaacat gttattcaaa ttatctaagg
    37801 aaaaaataga gctaggctta tctcgtttat cgccagcccg tcgtattttt ttgagttttg
    37861 ccttggtcat tttactaggc tctcttcttt tgagcttgcc ctttgtccaa gttgaaagct
    37921 cacgagcgac ttattttgat catcttttca ctgctgtctc tgcagtctgt gtgacaggtc
    37981 tctcaaccct tccagtagct cacacctata atatctgggg ccaaataatc tgtttgctct
    38041 tgattcagat cggtggtcta gggctcatga cctttattgg ggttttctat atccagagca
    38101 agcaaaagct tagtcttcgt agccgtgcaa ctattcagga tagttttagt tatggagaaa
    38161 ctcgatcttt gagaaagttt gtctattcta tttttctcac gacctttttg gttgagagct
    38221 tgggagctat tttgcttagt tttcgcctta ttcctcaact tggctgggga cgtggtcttt
    38281 ttagttccat ttttctagcg atctcagcct tctgtaatgc cggttttgat aatttaggga
    38341 gcaccagttt atttgctttt cagaccgatt tactggtcaa tctggtgatt gcaggcttga
    38401 ttattacagg cggccttggt tttatggtct ggtttgattt ggctggtcat gtaggaagaa
    38461 agaaaaaagg acgtctgcac tttcatacga agcttgtatt attattgact ataggtttgt
    38521 tgttatttgg aacggcaact actctctttc ttgagtggaa caatgctgga acgattggca
    38581 atctccctgt tgccgataag gttttagtta gcttttttca aacagtgacg atgcgaacag
    38641 ctggcttttc tacgatagat tatactcagg ctcatcctgt gactcttttg atttatatct
    38701 tacagatgtt tctaggtggg gcacctggag gaacagctgg gggactcaag attacgacat
    38761 tttttgtcct cttggtcttt gcacgaagtg agcttctagg cttgcctcat gccaatgttg
    38821 cgagacgaac gatcgcgccg cgaacggttc aaaaatcctt tagtgtcttt attatctttt
    38881 tgatgagctt cttgatagga ttgattctgc tagggataac agccaaaggc aatcctccct
    38941 ttatccacct catatttgaa accatttcag ctcttagtac agttggtgta acggcaaatc
    39001 tgactcctga ccttgggaaa ttggctctca gtgttatcat gccacttatg tttatgggac
    39061 gaattggtcc cttgaccttg tttgttagct tggcagatta ccatccagaa aagaaagata
    39121 tgattcacta tatgaaagca gatattagta ttggttaaga aaggaaagag catgtcagat
    39181 cgtacgattg gaattttggg cttgggaatt tttgggagca gtgtcctagc tgccctagcc
    39241 aagcaggata tgaatattat cgctattgat gaccacgcag agcgcatcaa tcagtttgag
    39301 ccagttttgg cgcgtggagt gattggtgac atcacagatg aagaattatt gagatcagca
    39361 gggattgata cctgcgatac cgttgtagtc gcgacaggtg aaaatctgga gtcgagtgtg
    39421 cttgcggtta tgcactgtaa gagtttgggg gtaccgactg ttattgctaa ggtcaaaagt
    39481 cagaccgcta agaaagtgct agaaaagatt ggagctgact cggttatctc gccagagtat
    39541 gaaatggggc agtctctagc acagaccatt cttttccata atagtgttga tgtctttcag
    39601 ttggataaaa atgtgtctat cgtggagatg aaaattcctc agtcttgggc aggtcaaagt
    39661 ctgagtaaat tagacctccg tggcaaatac aatctgaata ttttgggttt ccgagagcag
    39721 gaaaattccc cattggatgt tgaatttgga ccagatgacc tcttgaaagc agatacctat
    39781 attttggcag tcatcaacaa ccagtatttg gataccctag tagcattgaa ttcgtaaaga
    39841 gggatgaccc ctcttttttg atgcttaaga tggcaaatag agacagaagc cccttgtctt
    39901 ctagtaaaag ttcttcaaag gctggacttt atggtaaaat agaaggaagt gacaagagag
    39961 agtaatactc aatgaaaatc aaagatcaaa ctaggaaact agctgcgggc tgctcaaaac
    40021 actgttttga ggttgtggat agaactgacg aagtcagtaa catctatacg gcaaggcgac
    40081 gttgacgcgg tttgaagaga ttttcgaaga gtataagaaa aaatcagtcc cctaaaggag
    40141 cagattatga agttattgtc tatcgccatt tctagctata atgcagcagc ctatcttcat
    40201 tactgtgtgg agtcgctagt gattggtggt gagcaagttg ggattttgat tatcaatgac
    40261 gggtctcagg atcagactca ggaaatcgct gagtgtttag ctagcaagta tcctaatatc
    40321 gttagagcca tctatcagga aaataaaggc catggcggtg cggtcaatcg tggcttggca
    40381 gaggcttctg ggcgctattt taaagtagtt gacagtgatg actgggtgga tcctcgtgcc
    40441 tacttgaaaa ttcttgaaac cttgcaggaa tttgagagca agggtcaaga ggtggatgtc
    40501 tttgtgacca attttgtcta tgaaaaggaa ggtcagtctt gtaagaagag tatgagttac
    40561 gattcagtct tgcctgttcg gcagattttt ggctgggacc aggtcggaaa tttctccaaa
    40621 ggccagtata tcatgatgca ctcgctgatt tatcggacag atttgttgcg tgctagccag
    40681 ttctaattgc ctgaacatac tttttatgtc gataatctct ttgtctttac gccccttcag
    40741 caggtcaaga ccatgtacta tctgcctgtc gatttctatc gttatttgat tgggcgtgag
    40801 gaccagtctg tcaatgagca agtgatgatt aagtgcattg accagcaact caaggtcaat
    40861 cgactcttgg tagaccaact ttatttgtcc caagtgagtc atcccaaaat gcgagaatat
    40921 ctgctgaatc atattgaaat cacgacggtg atttccagta ccctgctcaa ccgatctgga
    40981 acagcggagc atctggcaaa aaaacgccaa ttgtggacct atattcagca gaaaaatcca
    41041 gaagtctttc aggctattcg taagaccatg ttgagccgtt tgaccaaaca ttctgtcttg
    41101 ccagatcgca aactgtccaa tgtcgtctat caaatcacca aatctgttta tggatttaat
    41161 t
//
LOCUS       DBEJJV010000014        40330 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.014, whole genome shotgun sequence.
ACCESSION   DBEJJV010000014 DBEJJV010000000
VERSION     DBEJJV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 40330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40330
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.014"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            206..1687
                     /gene="mgaSpn"
                     /locus_tag="ACL3GT_000864"
                     /gene_synonym="mgrA"
     CDS             206..1687
                     /gene="mgaSpn"
                     /locus_tag="ACL3GT_000864"
                     /gene_synonym="mgrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor transcriptional regulator
                     MgaSpn"
                     /protein_id="HGR0516548.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2049..3050
                     /locus_tag="ACL3GT_000865"
     CDS             2049..3050
                     /locus_tag="ACL3GT_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0516549.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     KVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3201..4118
                     /locus_tag="ACL3GT_000866"
     CDS             3201..4118
                     /locus_tag="ACL3GT_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516550.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAVRLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4129..5019
                     /locus_tag="ACL3GT_000867"
     CDS             4129..5019
                     /locus_tag="ACL3GT_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0516551.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5048..6664
                     /locus_tag="ACL3GT_000868"
     CDS             5048..6664
                     /locus_tag="ACL3GT_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0516552.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVENLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6674..7993
                     /locus_tag="ACL3GT_000869"
     CDS             6674..7993
                     /locus_tag="ACL3GT_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR0516553.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKIEQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            8516..8884
                     /locus_tag="ACL3GT_000870"
     CDS             8516..8884
                     /locus_tag="ACL3GT_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516554.1"
                     /translation="MRLSKEARVVLEELKLEYLKKGEDKTSGVIVDEIFKHFSSNFQK
                     VDWKSVQSAPKFNEILADYTSVNPTTLNLSNSTISTMSYIRDHFNYILDMKRTVYRSF
                     IIRLVLKAYKLEKEGTDIYL"
     gene            8997..9239
                     /locus_tag="ACL3GT_000871"
     CDS             8997..9239
                     /locus_tag="ACL3GT_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516555.1"
                     /translation="MKINEYLWRTSCLILLIIMSFFAGFGAKLEFTSYNPFLSVKFGL
                     VVALTVFVVQLLAILPAMVKRGNKNENVESNNSCEE"
     gene            9202..10593
                     /locus_tag="ACL3GT_000872"
     CDS             9202..10593
                     /locus_tag="ACL3GT_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HGR0516556.1"
                     /translation="MRMLNQTIRVKSKYPYLIRPRNIKIVRLFIQIFVFLLLISSWIA
                     IIPFIARLVFSMFFISLLFFVEKFFRSNFIAKLRNKLNIREALFYMLISLNLYDELDN
                     EVVDTAVLYFDVENNKVVVCAPLFGNRYLKTLKNLEEYLCPTLGLSLLSKKEEIDKIV
                     YVLGQKEEIEQYVFNSNTLTREFFKDIPSSIIKLSNTQKFSLKSNTNLGIYGRTGTGK
                     TIALQWYLFNALAKGCGIADNTYLGIVDGKAADLYRIGELLHEELGEQVAVGSSPQML
                     AQLSRKFIENMDARFKIIKQNSSLNADIYELDELGLVPNFLFVDELASIRDSCGSTKQ
                     GRETWNEILQNLGLIARKGRQAGCHLVLSTQDPNAENIPVELRNQISAVLYLGAPGAD
                     RLKMAFSMCELENVPTVSDRKGEALFYADGLNTVEPVLTIVPFVDLKTKKEFLNVVRN
                     ILPTNDGLPPLAK"
     gene            10849..11268
                     /locus_tag="ACL3GT_000873"
     CDS             10849..11268
                     /locus_tag="ACL3GT_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516557.1"
                     /translation="MVYNMTDTNIKIGLLDLEMSQFDIPKKVVILSVRVNNKYKEVNG
                     ENVKTDEVSKITSAVLDADKVKVLTEMGISTDDLKAINLEIIGNLDKIAKLAQNDALL
                     NVPVELIRPKVRLAWNMARNNWSGVKIVCEDIKVLGE"
     gene            11273..12292
                     /locus_tag="ACL3GT_000874"
     CDS             11273..12292
                     /locus_tag="ACL3GT_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HGR0516558.1"
                     /translation="MNTVRIDYFAVTVKNISPEKVLTDILLIPLENFTLNDWGINKYK
                     QHYSCSEIKVYFNADRLSMGVFIELKGQGCRQYEEFLNSNENNWIALISRLYHHNANF
                     TRLDIAHDIFDGSLDVQRIYDYCKKGLCISKAKHFEYHEKSVLDSGERVGETVAIGSR
                     GNQQWCIYNKRMEQLGKQELVEVSSWTRAELRCWQEKANIIAEQLYLKRPLSSIYFEA
                     INGHYRFIRPNAIDSNRWRRKKVEWWVNYLGTENQTVLSITRAKTTLRESEVWTEKQV
                     AKTLAKVYIAKYQAYDVQKAEDYIQNLLKEGLSKLTDNDEKDIEQYIREQNSSQLWGT
                     DGRSD"
     gene            12296..12478
                     /locus_tag="ACL3GT_000875"
     CDS             12296..12478
                     /locus_tag="ACL3GT_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HGR0516559.1"
                     /translation="MADTISNKDLISMGYRPSTANAIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVKELLGMEL"
     gene            12480..13607
                     /locus_tag="ACL3GT_000876"
     CDS             12480..13607
                     /locus_tag="ACL3GT_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0516560.1"
                     /translation="MAYIEYKQRGKKRLWSFSIRERSKSLLHKSGFKTKREAKIEAEK
                     VLHKLNTGSVLSSSMTLSELYNEWLDLKILPSNRSVVTKKKYLMRKKVIERLFGNKPV
                     SQIKPSEYQKIMNEYGETVSRNFLGRLNSCIRASIQMAIADKVIIEDFTAYVELFSSK
                     SGQKVEEKYLHAESDYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDE
                     VDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELN
                     IDNENNLIFQHFGYVYDVPDIATVNKAIKVMLKELQIFPLITTKGARHTYGSYLWHNN
                     IDLGVIAKILGHKDISMLIDVYGHTLEEKISEEFMAVKSLL"
     gene            complement(13690..13762)
                     /locus_tag="ACL3GT_000877"
     tRNA            complement(13690..13762)
                     /locus_tag="ACL3GT_000877"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13727..13729),aa:Lys,seq:ctt)
     gene            complement(14027..15298)
                     /locus_tag="ACL3GT_000878"
     CDS             complement(14027..15298)
                     /locus_tag="ACL3GT_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HGR0516561.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            15568..15768
                     /locus_tag="ACL3GT_000879"
     CDS             15568..15768
                     /locus_tag="ACL3GT_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516562.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            15972..16151
                     /locus_tag="ACL3GT_000880"
     CDS             15972..16151
                     /locus_tag="ACL3GT_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516563.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            16288..16467
                     /locus_tag="ACL3GT_000881"
     CDS             16288..16467
                     /locus_tag="ACL3GT_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HGR0516564.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            16504..16956
                     /locus_tag="ACL3GT_000882"
     CDS             16504..16956
                     /locus_tag="ACL3GT_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HGR0516565.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            17247..17717
                     /locus_tag="ACL3GT_000883"
     CDS             17247..17717
                     /locus_tag="ACL3GT_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HGR0516566.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            17736..18824
                     /locus_tag="ACL3GT_000884"
     CDS             17736..18824
                     /locus_tag="ACL3GT_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HGR0516567.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            18805..19233
                     /locus_tag="ACL3GT_000885"
     CDS             18805..19233
                     /locus_tag="ACL3GT_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0516568.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            19371..20321
                     /gene="prmA"
                     /locus_tag="ACL3GT_000886"
     CDS             19371..20321
                     /gene="prmA"
                     /locus_tag="ACL3GT_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HGR0516569.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            20323..21066
                     /locus_tag="ACL3GT_000887"
     CDS             20323..21066
                     /locus_tag="ACL3GT_000887"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HGR0516570.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            21077..22873
                     /gene="pepF"
                     /locus_tag="ACL3GT_000888"
     CDS             21077..22873
                     /gene="pepF"
                     /locus_tag="ACL3GT_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0516571.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(22933..23610)
                     /locus_tag="ACL3GT_000889"
     CDS             complement(22933..23610)
                     /locus_tag="ACL3GT_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HGR0516572.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQKKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEQGKEF
                     LEKEWGI"
     gene            23857..24627
                     /locus_tag="ACL3GT_000890"
     CDS             23857..24627
                     /locus_tag="ACL3GT_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516573.1"
                     /translation="MLYLLGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDFLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            24620..25384
                     /locus_tag="ACL3GT_000891"
     CDS             24620..25384
                     /locus_tag="ACL3GT_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516574.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            25809..26600
                     /locus_tag="ACL3GT_000892"
     CDS             25809..26600
                     /locus_tag="ACL3GT_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HGR0516575.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLVFTSF
                     AKEIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSILFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDDLKEAIQSFQY"
     gene            26711..27379
                     /locus_tag="ACL3GT_000893"
     CDS             26711..27379
                     /locus_tag="ACL3GT_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0516576.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFANKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLIIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(27404..27763)
                     /locus_tag="ACL3GT_000894"
     CDS             complement(27404..27763)
                     /locus_tag="ACL3GT_000894"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516577.1"
                     /translation="MLKAVFEVVDKTDEVSSKHCFEVADRTDKVSLKHCFEVADRTDE
                     VSLKHCFEVADRTDEVSLKHCFEVVDETDEVSLKHCFEVVDETDEVSNHTYGKVKLTW
                     FEEIFEEYHTKKPCSSR"
     gene            complement(27813..28346)
                     /gene="queF"
                     /locus_tag="ACL3GT_000895"
     CDS             complement(27813..28346)
                     /gene="queF"
                     /locus_tag="ACL3GT_000895"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033739 - preQ1 synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046857 - oxidoreductase activity, acting
                     on other nitrogenous compounds as donors, with NAD or NADP
                     as acceptor [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
                     /protein_id="HGR0516578.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEDLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(28651..28965)
                     /gene="trxA"
                     /locus_tag="ACL3GT_000896"
     CDS             complement(28651..28965)
                     /gene="trxA"
                     /locus_tag="ACL3GT_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0516579.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(28982..29203)
                     /locus_tag="ACL3GT_000897"
     CDS             complement(28982..29203)
                     /locus_tag="ACL3GT_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0516580.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(29302..29682)
                     /locus_tag="ACL3GT_000898"
     CDS             complement(29302..29682)
                     /locus_tag="ACL3GT_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HGR0516581.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETVAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKILASLQKTVEESLEAGLDFLI"
     gene            complement(29825..30778)
                     /locus_tag="ACL3GT_000899"
     CDS             complement(29825..30778)
                     /locus_tag="ACL3GT_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HGR0516582.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(30846..32055)
                     /gene="sstT"
                     /locus_tag="ACL3GT_000900"
                     /pseudo
     CDS             complement(30846..32055)
                     /gene="sstT"
                     /locus_tag="ACL3GT_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            32194..32754
                     /locus_tag="ACL3GT_000901"
     CDS             32194..32754
                     /locus_tag="ACL3GT_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel domain-containing
                     protein"
                     /protein_id="HGR0516583.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            32811..33719
                     /locus_tag="ACL3GT_000902"
     CDS             32811..33719
                     /locus_tag="ACL3GT_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HGR0516584.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLENHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDKPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            33734..34261
                     /locus_tag="ACL3GT_000903"
     CDS             33734..34261
                     /locus_tag="ACL3GT_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HGR0516585.1"
                     /translation="MAIENYIPDFAVEAVYDLTVPSLQAQGIKAVLVDLDNTLIAWNN
                     PDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVEKFGIDYVYWALKPFTFGIDRA
                     MKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKPLVQHDSIKTQINRTRERRVMR
                     KITEKYGPITYKKGI"
     gene            34264..35370
                     /gene="yqeH"
                     /locus_tag="ACL3GT_000904"
     CDS             34264..35370
                     /gene="yqeH"
                     /locus_tag="ACL3GT_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HGR0516586.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFITGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            35584..35895
                     /gene="yhbY"
                     /locus_tag="ACL3GT_000905"
     CDS             35584..35895
                     /gene="yhbY"
                     /locus_tag="ACL3GT_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HGR0516587.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            35947..36576
                     /locus_tag="ACL3GT_000906"
     CDS             35947..36576
                     /locus_tag="ACL3GT_000906"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HGR0516588.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            36576..37169
                     /gene="yqeK"
                     /locus_tag="ACL3GT_000907"
     CDS             36576..37169
                     /gene="yqeK"
                     /locus_tag="ACL3GT_000907"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HGR0516589.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            37170..37670
                     /locus_tag="ACL3GT_000908"
     CDS             37170..37670
                     /locus_tag="ACL3GT_000908"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0516590.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            37683..38036
                     /gene="rsfS"
                     /locus_tag="ACL3GT_000909"
     CDS             37683..38036
                     /gene="rsfS"
                     /locus_tag="ACL3GT_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HGR0516591.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            38356..39096
                     /locus_tag="ACL3GT_000910"
     CDS             38356..39096
                     /locus_tag="ACL3GT_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0516592.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            39106..40203
                     /locus_tag="ACL3GT_000911"
     CDS             39106..40203
                     /locus_tag="ACL3GT_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HGR0516593.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGTEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLSYILAQARENVLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNLSIAQQNFGRVPIRIETN"
BASE COUNT        12373 a         7079 c         8760 g        12118 t
ORIGIN      
        1 atataatctt tagacttgaa tttgattctg tattcacgcc ctcaatagac ggtaaaataa
       61 gaaaattgtt tatatattgt ctccgtagtg ttattatacg aaataaaaga ttttaggaaa
      121 agtcgttata tcatgctata cctattcttt gtggtataat tgcaagaggt ttaatccgat
      181 aatttataaa gagagaaaga tattcatgag agatttatta tctaaaaaaa gtcataggca
      241 attagaatta ttagaattat tatttgaaca taaacgttgg tttcatcgtt ctgaactagc
      301 agagttatta aattgtacag aacgtgcagt caaagatgat ctatcccatg ttaaatctgc
      361 ttttcctgac ttgatttttc attcttctac taatggtata cgcattatta ataccgatga
      421 tagtgatatt gaaatggttt accatcattt ctttaaacat tcaactcatt tttcgatttt
      481 agaattcatc ttctttaatg aaggttgtca agctgagagt atttgtaaag aattttatat
      541 cagttcatct tcgctctatc gtattattag ccaaatcaat aaagtgatta aaaggcaatt
      601 tcaatttgaa gtcagtctga cccctgttca aatcattgga aatgagagag acattcgtta
      661 cttttttgca caatattttt cagaaaaata ttatttccta gaatggccat ttgaaaattt
      721 ttcatcagag ccactatctc aattgttaga attggtttat aaggaaacaa gctttccaat
      781 gaatttgtca acgcatagaa tgctaaagtt gctcctagtt acgaacctat atagaataaa
      841 gtttggtcat tttatggaag tagataaaga ttcttttaac gaccaaagtt tggatttttt
      901 aatgcaggca gaaggaatag aaggtgttgc tcagagtttt gaatcagaat acaatatctc
      961 tttagatgaa gaagttgttt gccaattatt tgtgtcttac tttcaaaaaa tgtttttcat
     1021 agatgaaagt ctctttatga aatgcgtaaa aaaggatagt tatgttgaaa aatcttacca
     1081 tctattgagt gattttattg atcagatttc agtcaagtat cagattgaaa tggagaataa
     1141 ggataatctg atttggcatc tgcataatac cgcacatctg tatcgtcaag agttgtttac
     1201 tgagtttatt ttatttgatc aaaaagggaa tacaatcagg aactttcaaa atatttttcc
     1261 aaaatttgtt tcagatataa aaaaagagct ttctcactat ttagagactc ttgaggtttg
     1321 ttctagttca atgatggtaa atcatctatc ttataccttc atcactcata ccaaacattt
     1381 ggtgattaat ttgctacaaa atcagcctaa actaaaggtt ttagttatga gtaattttga
     1441 tcagtatcat gcaaaattcg ttgcagagac actttcttat tactgtagca ataattttga
     1501 actggaagtt tggactgaat tagaattatc aaaggaatct ttagaagatt caccttatga
     1561 tatcattatt tctaatttta ttattcctcc tattgaaaat aagagactca tctattcaaa
     1621 taatataaac acggtctcac tcatatactt gttaaatgcc atgatgttta ttcgattaga
     1681 tgagtaacca aaaataacaa aaaaacgcta tttcgcgttt gaactgtacc tcaaaagtta
     1741 gacagaaaaa atctaatttt tggggtgttt ttgttaagaa aagaccttca atcatttaag
     1801 caaaatgtac atctagattt atagccctct aaaactcttg ctttttttgt agaagatacg
     1861 aaaaaagcca taaaaccaag gcttttcctg ttttatgtag atgtttacac atgaaaattg
     1921 aagtattttc aaaagctaat tggagtgatt ttattcatga tgggataaat gatctggcca
     1981 aaaatgattg agaaatagtt gcttaaaaag catttgcatg atactatata ttgaaaggag
     2041 gtgataatat ggtagaacaa agaaaatcaa ttaccatgaa agatgttgct ttagaagcag
     2101 gagttagtgt tggaactgtt tcacgtgtaa ttaataaaga aaaaggcatt aaagaagtaa
     2161 ctttgaaaaa agtggaacaa gcgattaaaa ctttgaatta cattccagat tactatgcta
     2221 gaggaatgaa aaaaaatcga acagaaacga ttgcaatcat tgtaccaagt atctggcatc
     2281 ccttcttttc agaatttgct atgcatgtgg aaaatgaagt ctataagaga aataacaaat
     2341 tactcttatg ttctataaat ggtacaaata gagagcaaga ctatctggag atgttgcgtc
     2401 ataataaagt tgatggagtg gttgccatta cctatagtcc aattgaacat tacttgacgt
     2461 caggaattcc ctttgttagt attgaccgca catactcaga tattgccatt ccttgtgttt
     2521 catcagataa tgatgcaggt ggaagagaag cagctaaaca attaattagt aaaggatgtc
     2581 agcatttagc ctttgtgggc ggacataata caaccattaa tgaaaccaaa cgtcgtagaa
     2641 tttcatttga aaagtatgtc caagagcata aaatacctct tagtattttt gatttggatg
     2701 agaaagttac tgactattat ggaaagctag agagtttctt ggaagaaaat tcttctatag
     2761 atggaatttt tacaatcaac gattttacag ctttggatgt gattgaaata ctagaaaaaa
     2821 atggcaaacg tattcctcat gatgtccaaa ttattggata cgatggaatt aaaatggctg
     2881 gagatagaga ttatctactt tcaactattg aacaaccatt ggaagaaatg gcaaaagaag
     2941 cggttcgtat tttgtttgat ataattgatg gaaagactgt taatttgcag acaatcctac
     3001 cagtaaaatt tgttgaagga aaaacaacaa aaaatgaaaa taagtcttga cagaaagcgc
     3061 tatcaatgat agaatgaatt cagataaaaa gatttatttt taaaacaaaa atgaaacgtt
     3121 tcaaaaaaag aaataaaaag acagcgccaa gcgctatctt ttatagaaaa aatgaaacgt
     3181 ttcaaaaaaa ggaggttgct atgaatagca aagcgaagca agtttctctt tgggaaagaa
     3241 tcaagaaaca aaaactcttg ttattgatga ctgtccccgg tttagtttta acctttatct
     3301 ttaaatacat ccctatgtat ggggttttaa tcgcatttaa agattacaat cctttaaaag
     3361 gaattttagg gagtgattgg attggttttt ctgagtttac aaaattcata tcctctccca
     3421 actttggtat cttgttagcc aacacattaa aattaagtat ctatggttta ttgcttggct
     3481 ttttaccacc aatcattctt gcgattatgc tcaatcaact cttgagtgaa aaagtcaaaa
     3541 aacgaattca gctcatttta tacgcaccaa actttatctc agtcgttgtt attgtcggta
     3601 tgattttcct cttcttttca gtgggaggac caatcaacaa ttttctttct atgtttggaa
     3661 tgaaggctga cttcttgaca aatccagact tctttagacc cttatacatc tttagtggta
     3721 tctggcaagg aatgggctgg gcttcaacgc tctacacggc aacattggta aatgtagatc
     3781 cagccttagt agaagcagtt cgactggatg gagccaatat cttccaacga atctggcaca
     3841 ttgatattcc agctcttaag cctattatgg ttatccaatt tgttttagct gcaggtggaa
     3901 ttatgaatgt cggatatgaa aaagcattct tgatgcagac atcgttaaat ttgccaactt
     3961 ctgaaattat ctcgacatat gtctataaag ttggtcttgt atcaggagac tattcttact
     4021 caacagcggt tggtttgttt aatgcagtga ttaacgtagt attgcttgtt gcagttaacc
     4081 aaatcgttaa acgcatgaat aatggtgaag gaatttaagg aggaaagtat gaaaaattcg
     4141 attatggata caaaatttga tagacgtatc ttactcttaa ataaaatcat tattgtcttt
     4201 atcgttttga tgactttgct tcctttactt tatatcgtcg tagcatcctt tatggatcct
     4261 aaggttctgg ttagtagagg gattagcttt aatccagccg attggactgt agaaggttac
     4321 cagcgtgtat tcagtgacca atctattcta agaggtttta tcaattctct actatactct
     4381 tttggatttg cagctttaac agtattgcta tctgtgttta cagcttatcc tctttctaag
     4441 aaagacttgg ttggacgtcg ttggattaac tacttcttga ttgtgactat gttctttggt
     4501 ggtggtttag tcccaactta cttgctcgta aaagaattgg gaatgctcaa tactccatgg
     4561 gctatcattg ttccaggtgc tgtcaatgtt tggaatatta ttcttgctag ggcctatttc
     4621 caaggattgc ctgaagaatt agttgaagct gctgtcattg atggagcgaa tgacttgcag
     4681 attttcttta aaatcatgct tcctcttgca aaaccaatta tgtttgttct cttcctctat
     4741 gcttttgtag gacagtggaa ctcatacttt gatgcaatga tttatatcaa ggatccaaac
     4801 ttggaaccat tgcaacttgt acttcgtaaa attctcattc agagccaacc aggtcaagac
     4861 atgattggag cacaagcggc tatgaatgaa atgaaacgtt tagctgaatt gattaaatac
     4921 gcaactattg tcatttccag cttgccattg attgttatgt atccattctt ccaaaaatac
     4981 tttgataaag gaattatggc tggttcactt aaaggataaa aaaagaaaaa ataaaaggag
     5041 ttttctcatg aaattcaaaa cattctcaaa atcagcagtt ttgttgacag ctagtttagc
     5101 agtacttgca gcctgtggct caaaaaatac agcttcaagt ccagattata agttggaagg
     5161 tgtaacattc ccgcttcaag aaaagaaaac attgaagttt atgacagcca gttcaccgtt
     5221 atctcctaaa gacccaaatg aaaagttaat tttgcaacgt ttggagaagg aaactggcgt
     5281 tcatattgac tggaccaact accaatccga ctttgcagaa aaacgtaact tggatatttc
     5341 tagtggtgat ttaccagatg ctatccacaa cgacggagct tcagatgtgg acttgatgaa
     5401 ctgggctaaa aaaggtgtta ttattccagt tgaaaatttg attgataaat acatgccaaa
     5461 tcttaagaaa attttggatg agaaaccaga gtacaaggcc ttgatgacag cacctgatgg
     5521 gcacatttac tcattcccat ggattgaaga gcttggagat ggtaaagagt ctattcacag
     5581 cgtcaacgat atggcttgga ttaacaaaga ttggcttaag aaacttggtc ttgaaatgcc
     5641 aaaaactact gatgatttga ttaaagtcct agaagctttc aaaaacgggg atccaaatgg
     5701 aaatggagag gctgatgaaa ttccattttc atttattagt ggtaacggaa acgaagattt
     5761 taaattccta tttgctgcat ttggtatagg ggataacgat gatcatttag tagtaggaaa
     5821 tgatggcaaa gttgatttca cagcagataa cgataactat aaagaaggtg tcaaatttat
     5881 ccgtcaattg caagaaaaag gcttgattga taaagaagct ttcgaacatg attggaatag
     5941 ttacattgct aaaggtcatg atcagaaatt tggtgtttac tttacatggg ataagaataa
     6001 tgttactgga agtaacgaaa gttatgatgt tttaccagta cttgctggac caagtggtca
     6061 aaaacacgta gctcgtacaa acggtatggg atttgcacgt gacaagatgg ttattaccag
     6121 tgtaaacaaa aacctagaat tgacagctaa atggattgat gcacaatacg ctccactcca
     6181 atctgtgcaa aataactggg gaacttacgg agatgacaaa caacaaaaca tttttgaatt
     6241 ggatcaagcg tcaaatagtc taaaacactt accactaaac ggaactgcac cagcagaact
     6301 tcgtcaaaag actgaagtag gaggaccact agctattcta gattcatact atggtaaagt
     6361 aacaaccatg cctgatgatg ccaaatggcg tttggatctt atcaaagaat attatgttcc
     6421 ttacatgagc aatgacaata actatccaag agtctttatg acacaggaag atttggacaa
     6481 gattgcccat atcgaagcag atatgaatga ctatatctac cgtaaacgtg ctgaatggat
     6541 tgtaaatggc aatattgata ctgagtggga tgattacaag aaagaacttg aaaaatacgg
     6601 actttctgat tacctcgcta ttaaacaaaa atactacgat caataccaag caaacaaaaa
     6661 ctagaggttg attatgggag ataagaaata cacagtagaa aaagccaatc gttttatagc
     6721 agaaaataaa catctcgtta atactcaata taagcctgaa gaacattttt cagctgagat
     6781 tggttggatc aatgatccaa atggatttgt ctattttcgt ggagaatacc atctctttta
     6841 tcaattctat ccatatgata gtgtttgggg gcctatgcac tggggacatg ctaaaagtaa
     6901 ggacttggtg acttgggagc acttgccagt ggcacttgct cctgaccaag attatgaccg
     6961 aaatggttgt ttctcaggct ctgccattgt caaggatgat cgcctctggc tcatgtacac
     7021 tggacatatc gaagaagaaa ccggtgtccg ccaagtgcaa aatatggcat tttcagatga
     7081 cgggattcac tttgaaaaga ttgaacaaaa tccagttgca actggatcag acttgccaga
     7141 tgagttgatt gctgctgatt ttcgtgatcc aaaactcttt gaaaaagatg gacgctatta
     7201 ctccgtagta gctgccaaac acaagaataa tgtgggctgt atcgttctac tagggtccga
     7261 taacctagta gaatggcagt tcgaatccat ctttttaaaa ggggtagaac accaaggctt
     7321 tatgtgggaa tgcccagatt acttcgagtt agatgggaaa gattgcctta ttatgtcacc
     7381 catgcgttat cagcgtgagg gagactcata tcataacatc aactcatcgc ttttgttcac
     7441 gggtaaggta gattggggag aaaaatgttt tatcccagaa tcagttcaag aaattgatca
     7501 tggccaagac ttctatgcgc ctcaaacatt gttggacgat caaaatcgtc gtatcctgat
     7561 tgcttggatg cagacatggg ggcgtaccct tccaacccat gaccaagaac acaaatgggc
     7621 atgtgccatg actttaccta gaattttaag attggaagat ggcaaactaa gacaattccc
     7681 tgttaaaaaa ggccaatatc aaatccaaat agataaagat tgtcattacc acttaggaaa
     7741 tgatatagat tatcttgaat ttggttatga tagtaatgcg cagcaagttt acattgatcg
     7801 tagccatctt attcaaaaaa ttctaggtga agaagaacag gacactagtc gacggtatgt
     7861 agatattgaa gctaaagaat tggaagttgt tctagataaa aattccatcg agatttttgt
     7921 caatcaaggt gaagcaagct tgactgcaac ttattactta acggtgccag ctgagctatc
     7981 acgaattgat taaaaattaa gttatttctc ctaaagaaaa agttctcttt ctaaaatagt
     8041 ggaaagagga ctttttgtgt tttgggtata taagcttagt ttatggtatt tgtaaaattg
     8101 gtgttggatt atgatttaag ctagttttct aaagaatttg aaaaaaattt tatttaagca
     8161 aaaaaaaccc ttggttccaa ggcttttcct gttgtattta tatgccccct acaagtatat
     8221 tatgatacat agtattaagt gattatttat ttttgaggct tttcttattc taaaagtagg
     8281 tatatgagtt tatggacatt gtaattcaca acaaattcac ggcagaaaat acaattaggt
     8341 agtttgtaat tttaaaatta atgcgaaact aattaaattt aaaaaaaatc aactttcttc
     8401 cttgaccttt ttaaaaaatt ttggtatact taatgggtaa tcaagattga acaaagaatc
     8461 aagctttttc aacttgcaaa attatcagaa aggaggctct ataatgagga ttcaaatgag
     8521 attatctaaa gaagctcgcg ttgttttaga agaattaaaa ttagaatatt taaaaaaagg
     8581 tgaagacaaa acatcaggag taatcgttga tgaaattttt aaacatttta gttctaattt
     8641 tcaaaaagta gattggaaat ctgttcaaag tgcacctaag tttaatgaaa ttttggcaga
     8701 ttatacttca gttaatccca caacacttaa tttatctaat agtacaataa gtacaatgtc
     8761 ttacattaga gaccatttta actacatatt agatatgaaa agaaccgtct atcgttcatt
     8821 cataattcgc ctagtcttga aggcttacaa attagagaag gaaggcaccg atatttattt
     8881 ataatagatg tttatttcat ctattataat tttagcatga tgagtagtca aaactatatc
     8941 taaagggagg ttaatctctc tctttatttt taaaatttga aaggaaaaat acaaaaatga
     9001 aaattaatga atatttatgg agaacgagct gtcttatact gctaattatc atgagcttct
     9061 ttgcaggctt cggagctaaa ttagagttta catcttataa cccgttttta tctgttaaat
     9121 ttggtttggt cgtagctctg acagtctttg tagttcaatt gttagccata ctgccagcca
     9181 tggttaaaag aggaaataaa aatgagaatg ttgaatcaaa caattcgtgt gaagagtaaa
     9241 tacccttact tgattcgtcc ccgaaatatt aaaattgtaa gattgtttat ccaaattttt
     9301 gtctttttac tcttaatatc ttcgtggatt gctataatcc catttattgc tcgtctagtc
     9361 ttttccatgt tttttataag tcttcttttt ttcgtagaga agttctttcg ttctaatttt
     9421 atagcaaaat tgagaaacaa gctcaatatc agagaagcct tgttttacat gttaattagt
     9481 ttaaatttat atgatgagct cgataatgaa gtagtagata cagcagtttt atattttgac
     9541 gttgagaata ataaagttgt tgtctgtgcc ccactatttg ggaaccgtta tctgaaaacc
     9601 ttgaaaaatt tagaggaata tctctgtccc actttgggct tgtccttgct gtctaaaaaa
     9661 gaagaaatcg ataaaatagt atacgtgtta gggcagaaag aagaaataga acaatatgtt
     9721 tttaatagta acacattaac aagagaattt tttaaagata ttcctagttc aataatcaag
     9781 ctgtcaaata cacagaaatt tagtctaaag tccaacacta acctaggtat atatggaaga
     9841 acggggacag gcaaaacaat agctctgcaa tggtacttat ttaacgcact ggctaaaggt
     9901 tgtggtattg ctgataatac ttatttaggc atagtagatg gtaaggcagc tgacttgtat
     9961 cgtattggtg aacttcttca cgaagaactg ggagaacaag tggcagtagg ctcttcacca
    10021 caaatgcttg cccaattatc gagaaaattc attgagaata tggatgcaag atttaaaatt
    10081 atcaaacaga atagttcatt gaatgctgac atttatgagc tagatgagct gggactggta
    10141 cctaattttt tgttcgttga tgaactcgct tctattcgtg atagttgtgg ctctacgaaa
    10201 caaggtagag aaacatggaa tgaaattcta caaaatttag gcttgattgc acgcaaagga
    10261 cggcaggcag gttgccacct agtcctatct actcaagacc ctaatgccga aaacatcccc
    10321 gttgaattga ggaatcaaat ttcagcagtt ttataccttg gtgccccagg ggctgataga
    10381 ttgaagatgg cttttagcat gtgcgaatta gaaaacgttc ctacagtttc agatagaaaa
    10441 ggggaggctc tcttttatgc tgatgggctt aatacagtag agccagtgct aacaattgtg
    10501 ccatttgttg atttaaaaac taagaaagag tttttaaatg tagttagaaa catactgcca
    10561 actaatgacg gtcttcctcc cctagcgaaa tagggcgatt gccggaggca gaatcgagcg
    10621 gagcgctctc ttttcgctag gggagggaga gccaaccgac tgctttgcag gaggtcagaa
    10681 aaaacatccc cagtactaat agggggtgca cacatacatg aaatgtactc taaacccttg
    10741 atacgtgagg ggttacggct tactagttgc accaaggggt cgcaaactct tgggagagta
    10801 gggatgagag gtgtttccat gtatgatacg gaattaaagg agaaaaatat ggtttacaat
    10861 atgacagata caaacattaa aattggattg cttgaccttg agatgtcaca gtttgatatt
    10921 cctaagaaag tagtgatttt atcagttagg gtgaacaata aatacaaaga agtcaacggc
    10981 gaaaacgtga agacagatga agtaagtaaa attacttctg ctgttcttga cgctgacaaa
    11041 gtgaaagttc taactgaaat gggaatttct actgatgact taaaagctat taacctagaa
    11101 attatcggaa atctagataa gattgcaaaa cttgctcaaa atgatgcttt gttgaatgtt
    11161 cctgttgaat tgattcggcc taaagttcga ctagcttgga acatggctag gaataattgg
    11221 tctggtgtaa aaattgtgtg tgaggatatt aaagttctag gagaataatc ctatgaatac
    11281 agttagaata gattattttg ctgtgacagt taagaatatt tcgccagaaa aagttctgac
    11341 agacatcctt ttgattcctc ttgaaaactt taccttgaat gattggggca taaataagta
    11401 taagcaacat tattcttgtt cagaaattaa ggtgtatttt aatgctgata ggctttctat
    11461 gggtgtattt attgaattaa aagggcaagg ttgtcgtcaa tatgaagaat ttttaaacag
    11521 taacgaaaat aattggattg ctttgataag tcgtttatat catcataatg ccaactttac
    11581 tagactagat attgcccacg acatatttga cggtagctta gatgttcaac gaatatatga
    11641 ctattgcaag aaaggattat gtatctcgaa agcaaaacac tttgaatatc atgagaaatc
    11701 agttctagat tctggtgagc gtgtaggaga aacagttgca ataggttcac gaggtaatca
    11761 gcagtggtgc atatataata aacgcatgga gcaacttggt aagcaagagc ttgtagaagt
    11821 ttcatcttgg actcgcgcag agcttagatg ttggcaggag aaggctaata taattgcaga
    11881 gcagttatat ttaaaacgtc ccttatcgtc aatatatttt gaggctatca acggtcatta
    11941 tcgctttatt cgtccaaatg ctatagatag taatcgttgg agaagaaaaa aggttgagtg
    12001 gtgggtaaac tatctaggga cagaaaatca gacagttctg agtattacaa gggctaagac
    12061 gacgttacgg gagtctgaag tttggactga gaaacaggtt gcaaaaacat tagcaaaagt
    12121 ctatattgca aagtatcagg cctatgatgt tcaaaaggcg gaagattata ttcaaaactt
    12181 gctcaaagag ggactttcaa agctaactga taatgatgaa aaggatatag aacaatatat
    12241 aagagaacag aatagttccc aactttgggg aaccgatgga aggagtgact gacatatggc
    12301 agatactata tcaaataagg atttgatttc catgggctat aggccatcaa cagctaatgc
    12361 tattatccat caggcgagag aattacttgt atcacgaggc tatacatttt ataatcgcaa
    12421 acgtttgatg gttgttccaa aaagtgttgt gaaagagttg ttgggaatgg aattgtgaaa
    12481 tggcttatat cgagtataaa cagcgtggta agaaaagact ttggtccttc tctatacgag
    12541 aaaggagcaa gagcctactc cataaaagcg gatttaaaac aaaacgagaa gctaaaatag
    12601 aagcggagaa agttcttcat aagttaaata ctgggagtgt cttaagctct agtatgactt
    12661 tatcggagct ttataatgaa tggcttgatt taaaaatttt acctagcaat agaagtgtag
    12721 ttactaaaaa aaaatatctc atgagaaaga aggtcatcga aaggttattt ggaaataagc
    12781 ctgtatcaca aattaagcct agcgagtatc aaaaaattat gaatgagtat ggagagactg
    12841 tatcgagaaa tttcttagga agattgaatt cttgtattcg ggcaagtata cagatggcta
    12901 ttgctgataa ggtgataata gaggatttta ctgcttatgt tgagttgttc tcttctaaga
    12961 gtggacaaaa ggttgaggaa aagtatttgc atgctgagtc agattatcaa aaagttttag
    13021 tatatttgaa aaataagttt gattatcaaa aatctattgt accgtatgta atttatttcc
    13081 tttttaaaac tggcatgcgt ttctccgaat tgattgctct aacttgggat gaagttgacg
    13141 agcttaatga gcaacttaaa acttatcgtc gttacaacac cgctattcat aagtttactc
    13201 cacctaaaaa caatacttca ataagattag ttcctattac ttcagatatg ctttccttgt
    13261 taaaaacatt gaaaatattg caattaaaaa caaataaaga attaaatatt gataatgaaa
    13321 ataatttgat ttttcagcat tttggctatg tctacgatgt tccagatatt gcaacagtca
    13381 ataaagctat aaaagtaatg ttgaaggaat tgcaaatttt tccattgatt actaccaaag
    13441 gagctagaca cacttatggt agttatttat ggcataataa tattgatttg ggagttatag
    13501 cgaaaatttt aggacataaa gatatctcca tgttgattga cgtttatggg cataccttgg
    13561 aggaaaaaat tagtgaagag tttatggctg tgaaaagttt gttgtaaaaa cacggcaaat
    13621 tgcacgacaa tttttaaaag gaaggcaaaa aaagccctat attataaggc ttttcctgtt
    13681 gtatttatat gccccctaca gggatcgaac ctgtgaccca cggattaaga gtccgctgct
    13741 ctgccagctg agctaaggag gcaaagaaaa aagctgtatt ggtgccgaaa cttcacggtt
    13801 tgtattgaac ccgcgcaatt aagcaggtgg gcaactcgct ctaactgaag ctgtttccgt
    13861 gtgagacggc ctacatgctg ttagaagact tttgtttccc taataataca aaaaatagtc
    13921 ggtcaacact taagtgtgaa gtcgtacacc acagcgtttc tatacttata tgataccact
    13981 ttttcaaaaa aaatcaagag gaaagtgcaa ttttttgaaa aggatttcag atttttcgca
    14041 aacggtcgat agcttccttt ctttgagcca aagcccgttc atatttacca gtatcttctg
    14101 cttggaaata gtgatgatta cgaatttttt ctggcagata gtcttgcttg acccaatttc
    14161 caggatagtt gtgtggatag agatagtctt gggcattccc cagttccttg cttccactgt
    14221 agtgcccatc acgtaggtgt cgcggaatag gcaagtgccc tgatgttttg aggtcagcaa
    14281 gtgccttatc catagctaca taggctgagt tggattttgg agaaagggcc aaatcaatca
    14341 cgacattggc aatgagaatg cgggcttctg ggaacccaat cttctgggca gcatccagag
    14401 cagtcacggt atgaatctgg gcctcaggat tggctaagcc gatatcttca taggcgataa
    14461 cagtcaagcg acgagcgaga ctaggcagat ccccagcctc aatcaagcgg gcagtatagt
    14521 ggagactggc atccacatct gagccacgaa tagacttttg cagggcagat agaacatcat
    14581 agtgaccgtc tccatccttg tccatagtga tgtagcttct ctgaagacta ttttccatga
    14641 tgtctaaggt gatgtggcga atgccctcgt cattctcagg ggtagagaga acagctaagt
    14701 ccagtgagtt aaaggcagag cgaaggtctc cgtttgtaga ggttgcgatg aaatccagcg
    14761 catcctcatc tagttctatt ggaaaatcaa aaccacgttc agggttactt agagctatct
    14821 gcagggcctc tttgacgtct tggttagaca gaggttccaa ctcgaaaatt tgaactcggc
    14881 tacgaatggc aggagtgaca gagaagaaag gattttcagt cgttgctcca atcatgatga
    14941 ccagtccact ttccaagaga ggcaagagga agtcttgctt ggtcttatct agtcgatgaa
    15001 tttcgtctag caataggacg agaccaccag aaaatttagc ttcttccgag atttcttgca
    15061 gtcgcttttt actatcaact gtcgcattga aagttcgaaa ggcatacttg gtcgttccag
    15121 cgatggcaga ggcaatactg gttttgccga ttccaggagg gccatataga atcatggagg
    15181 acaggcggtt ggcttccacc atgcggcgga tgatttttcc aggtccgacc agatgctcct
    15241 gaccgatgac ctggtcgatg gttttagggc gcatgcgaag cgcgagattg tctggcatag
    15301 cagtcctttc tagcgtggat ttgagtagaa tgactcatct actatatctt actatgtcca
    15361 ttctagccta ttagttgtga tatttcaatg gttttgtaat aatcagggag tgagatagaa
    15421 tcttttttac tatttaattt aatgaggaga ggtatcagca tgagagattt gattttcctt
    15481 aaagctcaaa ataggatagt tgagcctaaa gaagtggaag tgctgacttg agaaataata
    15541 ttgctgaatg tcattgtatg aactataatg aaaagagagg tgataagcaa tggaaatgat
    15601 ggaccaagtc aggaaatttt gatttttaca aaacaaattc gtcattggat tcttagtgat
    15661 caagttattt cagggaaaag aaaacttttc ttccgggaag atactccaaa agagatttta
    15721 gatttgtacg aaaacattaa atctaaactt gattttgctt accaataagt ttattctaat
    15781 aatgggttga aaaaatatga aaaatagaat aattgatgtt tttgaagtag taaatcgcat
    15841 ccttgtaata actgttgaaa atcctgattt cgaagacttg agagttaatc atactcaatg
    15901 aaaatcaaag agcaaactag gaaactagcc gcaggctgta cttgagtacg gtaaggcgac
    15961 gttgacgtgg tttgaatttg attttcgaag agtatcagtt tgtaaaaatt ggagataaaa
    16021 aatatagagt acgcagtgtt cctatgattc attcaactcc gcctcaatct gtcttagatc
    16081 gagatacttt tacaattgac tatacagatg atgaattgct cgataaagaa gcagttttta
    16141 ctactcatta gaaaaatagg tctgaataaa ttggcttccc ttagaaccac atctaggggc
    16201 ttttatgtat aatagaataa taagtatcac tcctttacaa tacgtgtaac acgtgttata
    16261 atggtgttgt caggaggtaa aagcgctatg cctatgacac aaaaagagat ggttaaactc
    16321 cttacggccc atggttggat aaagactaga ggcggtaaag gctcccatat taaaatggag
    16381 aagcaagggg aaagacttat cacaatccct catggtgagc tgaataagta cactgaaaga
    16441 gggataagaa agcaagctgg gttgtaaaat tcagcccctg ttttttgata tggaggtagt
    16501 gaaatgttag ttacgtatcc agctttattt tattatgacg acacagacgg aacagaagcg
    16561 acttattttg tccatttccc agattttgaa tactcagcta cacaaggaga ggggatttct
    16621 gaggctttgg ctatggggtc ggagtggcta gggataactg ttgcagattt gatagagagt
    16681 gatggagagt tacctcagcc atcagatatc aatagcttgt ctttaattga taatgatcct
    16741 tttaaagatg atgaagattt cgtgtcaacc tatgaccttg ataaatcttt tatttctatg
    16801 gtatctgttg atgtatcaga atacctagga agtcaggaac ccataaaaaa gactttgacc
    16861 ataccaaaat gggcagataa gttgggacga gaaatgggac ttaacttttc tcagactttg
    16921 acagacgcta ttgcagataa gaaagttcaa gcctaagatt aagcgtggta tcgtggtaat
    16981 agtcaataaa aaagcacgtc cacttgtgct agttactcgc ctattgattt tatagattta
    17041 ttagcccttt cgcgggcttt ttatattgat ttttatgaga aatgaagaaa tcagactttt
    17101 aagaaaatca ctgataccaa gggtttaaat gaggtaatat ggtataatta ggacataaaa
    17161 taattttgtg gtaagatggt agtatctatt ttagcatatt tccgagcaat cggggcgatt
    17221 aaagagtcgc atagaaagag gacaaaatgg caacatacgg atttttagat gttttagagg
    17281 aagagttgga caagaacttt ccctttgact ttgagattag ctgggacaaa cgcaaccatg
    17341 cggtagaagt gagttttcta ttggaagcgc aaaatgctgc aggtgtggag atggtggatg
    17401 aagacggaga ggttttatca gatgacattc tttttgagga agcggtcctt ttctacaatc
    17461 ctgccaagtc aacagtcaat gaggaagact atttgactgt tattccttac ctgcctaaaa
    17521 aaggattttc ccgtgaattt ttagcttatt ttgcgctttt ccttaaagat actgctgagg
    17581 ttgggctaga tgtcctcatg gactttttgg aagacccaga agcagaggaa tttgtcatgg
    17641 aatggaacca agaagtcttt gaagaaggaa aagttggctt ggaagaggga gaattttatc
    17701 cttatccaag atactaggag ttggttggag gtgttatgaa gaaaattggg acttatttgg
    17761 tttatgtgct agcttttgtc tttattatgc tagcttttgc ttgtggaaca atcgcatttg
    17821 cagagttggg gtattccgca gttttagcct ttacttttgg ttatgccttc gctcttctaa
    17881 gcatgtattt aatctttatt cttcatgagc tgggtcatgc tttttgtggc tacttgacag
    17941 gctatcggct ggtggctttt ggattaggac attttatttt gaccaaaaag tcaggcaggt
    18001 ttcatcttag tagaacagcc attctgaaaa atgttggtgc tcaatacatt ggtttaaaag
    18061 aggatgaaag cgatcaaaga atcatcctga tgctttcagg aggcttgatg gttcatctcg
    18121 gcttgatatt attggcgata gtgtttggat ttttgacaag aagctggtat tttgcaggga
    18181 cttggatttt tcttaattta tctttcttcc taaataacat tttgccagtc gacatcaccg
    18241 atggagcaaa aatttgggaa ttactacaac accctgaaaa taccaaatac gcctacctgg
    18301 tattgagaca ttctgctcaa actttgctgg ctcctcaaga atatgatttg aaagactttg
    18361 ttcaagcagt tcctgaggat gcacgaggga gttttgcgga tggtgtatta ggtatgcaag
    18421 gtgaagtttc cattttggaa gggaaggaag aagtagctaa acagcagttt caagcattac
    18481 ttgagaggac aactactccg atgatgcaga cagttgccca actatccctg cttcatatcg
    18541 ccttgttgga aggagatttt gagcaagcgg agcaatatgc tagtattcga caggtcaaat
    18601 cgtttctgtc tctcaaactg tccaatcttc aagtgataca agcttggtat caatttaagg
    18661 taaagaaaga tgtagatcga actcgtaagg ctctcaagat tgctagacag aaaatggata
    18721 gtagtcgaat gttgagggac gagaaacgct attatgaaaa cttgttagca gagctggaaa
    18781 aggaaatgtt agaaggaact gaagatggaa ctagaaattt ctgatttccc aggctgtaag
    18841 attgctttgt tttgtgggga taagctcttg actatcttac gtgatgataa ggcaagtatt
    18901 ccctgggcca atatgtggga actgccaggt ggtggacgtg aaggtgatga aagtcctttt
    18961 gagtgtgtag cgcgtgaagt ttatgaagaa ctgggcattc atctgactga agattgtctg
    19021 ctttggagta aggtttaccc aagtatgctt tttgcagaca aacagtccgt ttttctagtt
    19081 ggtcagttga cacagaacca gtttgacagt atcgtatttg gagatgaagg acagggctat
    19141 cagctgatga atgttgagga atttcttagt tccagtcaag ttgtccctca gttgcaagag
    19201 agattaaaag attatttaaa agtaagtgat tagaaaggat ggttcagtta aatttctaaa
    19261 ctgaacccgc cctaaacact gtgccaaaaa gataaacttc tcttagacac aagcgtcttc
    19321 agagaatttc ctattttggt tttgtgtttt acgggcttgg tatcttaata atggaaacat
    19381 ggcaagagtt aaaagttaca gtgaagcgtg agggagagga gttggtttcc aatctcttga
    19441 ttgagctggg agcgcaagga gtcgcaatcg aagacagtat ggactatgtg ggaaatgttg
    19501 accgctttgg cgagattttc ccagaggtgg agcagcaaga agaaatcgtt gtgacagcct
    19561 actaccctga cacggtggat gtgacagtgg ttgaggcgga cttgcaggct cgcatatcag
    19621 aattgacgga ttttatggat ttgggagagt taaaaatagg tacgactgcc ttggctgagg
    19681 aagactgggc agacaactgg aagaaatact atgagccagc tcgtatcact catgatttga
    19741 ccatcgttcc ctcttggaca gactatgagg cgactgcggg agaaaaaatt atcaagctgg
    19801 atcctggcat ggcttttggt actggaaccc acccaactac caagatgagc ctttttgcct
    19861 tggaacaggt tcttcgtggt ggcgaaacgg tgctagatgt ggggactggt tcaggggttc
    19921 tctctattgc cagctcgctt ctgggggcta aagaaatttt cgcctatgac ctggatgatg
    19981 tggcggttcg tgtggctcag gaaaatattg agctcaaccc tggcatggaa aatatccatg
    20041 tagcggctgg agatttgctt aagggtgtgg aaattgaggc agatgtgatt gtggctaata
    20101 tcttggcgga tatcctcatt catctaatag acgatgccta tcgtttggtt aaggacgaag
    20161 gctacctgat catgagtggc attatcaagg acaagtggga catggtgcgc cagtcggctg
    20221 agtcagctgg atttttcctc gaaactcaca tggttcaagg ggaatggaat acctgtgtct
    20281 ttaagaaaac caaggatatc tctggtgtga ttggaggcta gcatgcagca gtattttgta
    20341 aaaggcagtg ctatctctcc tgtcactatc gaggacaagg aaaccagtaa gcatatgttt
    20401 caggttatgc gcttgaaaga agaggatgag gttaccttag tctttgatga tggcatcaag
    20461 cgcttggcgc gcgtgctgga tatggaaaat cgtcagtttg agttggtcca agaattaaat
    20521 gacaatgtgg aactaccagt ccaagtgacc atcgcatctg gatttcccaa gggagacaag
    20581 ctggagttca tcgctcaaaa agtaaccgaa ctgggtgcta gccaaatctg ggcctttcct
    20641 gcagactggt cagttgccaa gtgggatggc aagaaattgg gtaaaaaagt tgaaaaacta
    20701 gaaaaaattg cccttggagc agccgagcaa agcaagcgta atattgtacc aagtattaaa
    20761 cttttcgaga aaaaagcaga ttttctagct cagctggacc agtttgactt tatcatagta
    20821 gcctatgaag aatcagctaa agaaggagaa gccgctgcgc ttctgcaagc agtcactggt
    20881 cttgaaacag gagccaaact gctctttatc tttggtccag aaggcggtct ctcacctgca
    20941 gaaatcgaaa gttttgaagc taagggagcc gttttggtag gcctaggtcc tcgtattttg
    21001 cgagcagaaa cagcaccgct ttacgcctta tcagccctta gtgttttagt agaattagag
    21061 aaataagagg aagaaaatgg aacaaaaaca ccgttcagaa tttccagaga aggaactctg
    21121 ggacttaaca gccctatacc aagaccgtga ggatttcttg cgtgcaatcg agaaagctcg
    21181 tgaagacatc aaccagttta gccgtgatta caagggcaat cttcacactt ttgaggattt
    21241 cgagaaggcc tttgcggaat tagaacagat ctacattcag atgagccata ttggcaacta
    21301 tgcttttatg cctcagacga cggactatag caatgacgaa tttgccaata ttgcccaagc
    21361 tgggatggaa tttgaaacag atgccagcgt agccttgacc ttctttgacg atgccttggt
    21421 ggtagcagac gaggaagtct tggaccgttt gggtgaattg cctcacttga cggcagctat
    21481 tcgtcaggcc aaaatcaaaa aagcccacta tctaggggct gatgtggaga aggccttgac
    21541 caatctcggt gaagttttct atagtccgca ggacatttat actaagatgc gagctgggga
    21601 ttttgaaatg gctgactttg aagcccatgg caagacctat aaaaacagct ttgtcaccta
    21661 tgagaatttc taccaaaatc acgaggatgc tgaggttcgt gagaaatcct tccgttcctt
    21721 ctcagaggga cttcgtaagc accaaaatac ggctgcagca gcctatctgg ctcaggtcaa
    21781 gtctgaaaaa ctcttggctg atatgaaggg atacgactct gtatttgatt atcttctagc
    21841 tgaacaagaa gtggaccgtg tcatgtttga ccgccagatt gacctcatca tgaaggactt
    21901 tgcaccagtc gctcagagat acctcaagca tgttgccaag gtaaatggtc ttgaaaagat
    21961 gacctttgca gactggaaat tggacttgga cagcgccctg aatcctgaag tgactattga
    22021 cgatgcctat gatttggtca tgaagtcggt agaacctttg gggcaagaat attgtcagga
    22081 agttgctcgt taccaagaag agcgctgggt ggactttgct gctaacagtg gcaaggattc
    22141 cggtggttat gcggcggacc catatcgcgt acacccttat gtactcatga gctggacagg
    22201 ccgtttgagc gatgtctata ccttgattca tgaaatcggg cattctggtc aattcatctt
    22261 ttcagacaat caccaaagct atttcaacgc ccacatgtcg acctattatg ttgaagcacc
    22321 gtcaaccttc aatgaattgc tactcagtga ttacttagag aaccagtcta atgacccacg
    22381 tcaaaaacgc ttcgctctgg ctcatcgctt gacagacacc tacttccata actttatcac
    22441 ccacctcttg gaagccgcct tccagcgtaa ggtgtataca ttgattgaag aaggggagac
    22501 ctttggagca agcaaactca acagcattat gaaggaagtt ttgacagatt tttggggcga
    22561 tgccattgaa atcgacgacg atgcagcttt gacttggatg cgccaagctc actactatat
    22621 gggcttgtat agttacactt actctgctgg tcttgtcatc tcgacagctg gttaccttca
    22681 tcttaaaaac tcagaaactg gagctgaaga ctggctcaat ctcctcaaat caggtggtag
    22741 caagacacca cttgagtcag ccatgattat cggtgctgat atttcaacag acaaaccact
    22801 ccgtgatacc atccaattct tgtctgacac agttgaccag attatcgcct acagtgctga
    22861 gttgggggag taaggggata gagaggttgt tatagaatgg gtatggacag ttatttgctt
    22921 aaaagtccat gtttaaatcc cccattcctt ttcgaggaat tctttgccct gctctgtaat
    22981 ggtaagtgaa cgtggcgttt gtgcagggat gaccaattgt ttttcactga aaaattctaa
    23041 aagagcattg ccgagagctc cgccgacatg atttttacgt tcgctccaat ccaaacattt
    23101 agggcaaaat ttccgttttt tctttttcaa ttcatccgta tcaatgtgta attttttttg
    23161 gaaataagac ttcccagctt cagtgagttg gaagtctttt tctgattcgc tgaggagatt
    23221 ttcttgcaag agataattgg taatggaaat gccaagctca ccagcaatat ggtcatagca
    23281 ggtgcgagcg acctttaatt cctttttgtg aatgtgttgt ttataacttt tgacatcacg
    23341 ctgaggagag tagaagctga gaaattccag catttctgca atggcagcac tttttaaaga
    23401 ataataatga aaacgtccat aggtttgtag agtggttacc tgcgcttcgg taagtaattt
    23461 gaggtgatag ctgacagtat gttgcttgat tttggtaaag ctggcaattt cgttaaccgt
    23521 gtgagctttt ccatccatta gaatatctaa aatgtgcatc cgagaagggt ctgataagag
    23581 ttttgtgatg atgaaaatat ctggttccat aaaaattttc tccaaatttc atatatcgat
    23641 tattttctat cttttattat actataatca aagcacaaga aaaatagatt ttaaaaatgt
    23701 tttactagag aatattttaa attttattgt ctgagtttaa atggaggtaa aattacaaaa
    23761 gtaattgcag cagtatccac agttgaagga cgttaatctt aagattacat tctcaacatt
    23821 ttttcaaaag tgagatgaat taacaaagta tccaacatgc tctatttgtt ggggaaagaa
    23881 agagtgaaga agttaagtgt taaaaatcta aaaaagcaat atggttctta tgaagctgtc
    23941 aagggaatta gctttgaatt gggagaagga gagtgtttgg gtatcttggg aatcaacggt
    24001 gctggcaaaa catccacttt aaagatgatt tactcactga cctcaatttc ctcaggagag
    24061 attgatatct tggggcaaaa tattgaaacc aatcgtcgta agagtaaatc ttgtctgggt
    24121 attgtagggc aggaggatat gctggatatg accttgaatg tttatgataa tctttttgct
    24181 cacggtctat gttatggtat ctcatctgtc gaacttagga agagaatcga ttttctcttg
    24241 gattttgttc aactgagcaa acatgcgcaa aagatggtga atcagctgtc gggtgggatg
    24301 cgacgacgtc ttgtcttggc aagagctctc atcaatcggc ctgatattat cattttagat
    24361 gaaccgacag ttggtttaga cattcaatcc cgcaatatta tttgggataa acttttggag
    24421 ttgaaggaat taggtgtttc catcattatt acttcccact atatgaatga gattgaatat
    24481 ttgacagata gggtgctgat gctccaccaa gggactatca aagaagaagg aactgtagaa
    24541 gacttgctca tcaagtatga tgctgacaac cttgagacgc tttttttggg gttgactggg
    24601 acagagaagg aggacttgca tgtttaagtt atcatttcac tccatcggac acgttgtggt
    24661 acgcaactac atgagtttta gaaatttatt taaaatttca attgtcccca accttatcga
    24721 ccccctcttt tatcttttag caatgggatt tggagttggt gcttatttga cgcatgttaa
    24781 cggtatgctc taccgtgatt ttgtcattac aggtttaatt gctgcgactg ccatgtctgc
    24841 ggccactgca gaaacaacgg tcaatgcctt tatccagtat aagattgaaa agacttatga
    24901 tgctatgttg atgacgccaa tcaatacgaa tgatattgtg gtgggtcagg ctatctgggc
    24961 aggtattcgt gcagtgattt tcggtgggat tttttggctg atttccatgc ttatcacagc
    25021 gcattttcat gtcttgatgt tattgattcc tctgatttta tttatagtgg gttatttgtt
    25081 tggtgttttg ggactaatct ttacctactt ggcgccgtct agggaatttc tgaattacta
    25141 caatgttttg gtaatccgtc ctctttatat gttttcagat accttctttc ccattacttc
    25201 cttgccccca atacttggtg atttgacttg gttttctccc ttgtatcacg ctacccgcat
    25261 gattcgtatt atatggggag gtgaggtgac aggtttgtat cttcatctta tctggttgat
    25321 agccttggcg ctcttgataa cggtgcttcc tatgtatatg ttacatcgta gatattatag
    25381 atagtctaat tatttgtgat gttgtagtca tattctaatt tatactaaac gttattcgaa
    25441 tttggacagg tatgggaact gtgcctatca atattgtaat ttatggaagt tgaaatagta
    25501 cggttcagtt tttaaaatat tgttagaaat tgttttaaat tccctaatca atttgtatag
    25561 tttttatttc actttattat aactagtttt tcgcaatttt tgagacagga atgtgatttt
    25621 tgtgataagg ctctatcatt acaagttcat ttgtggtcat atggaataaa tcatttatat
    25681 atcttttcag aaatatgctg tttctctgaa tataaatgtc tttttctttt taacttaatt
    25741 ttacaaattg gtaaagtcat ttaagactgc ctttttgaac agttgctaga aatgtagagg
    25801 tattgaccat gtatcaagat ttactaagaa aaatagcaga agaaaaacca aattataacc
    25861 aggaagaaat ccagtggttg tttgatcatt tgggaaatcc ttctccagaa attcgtgatg
    25921 accttgtttt tacaagcttt gctaaggaga ttcaggaaga gctatttaca caggaacaat
    25981 ttcatttcat tgctgaggtg gtcttagctg atggagggtt agataaagag attgataagg
    26041 taggcttgtc aacacttgaa cgttctttta gggcacttat ttatgcaaat ctcttgtctg
    26101 cagatgctaa ccagcaatcg gttttttatc agggattaca atcagaaatt cgtaatgtcc
    26161 ttttaaatca aggcttgcac tatctttcaa aagaaaagga tacaacaggt ttctcaagtc
    26221 agtatggttg ggttcattct tttgcacatg gagccgattt actgacagag gtggtctgtc
    26281 atccagactt tcctataaac agaattcatg aagtatttga tatacttggc caactattta
    26341 aaagaatgtc gattctcttt acagatgatg aggattggcg tttagcaaga gtgatctatg
    26401 aacctatttt acaagggaag ttggagcaag aacaagtagc ttcttggata aaaactgttg
    26461 attttccgat agaagaaagg gaggattttt acaaattttc caactttaga tcctgtctgg
    26521 tggaagtcta tgtccaactt gaccagagaa atagtttaca agatgacctg aaagaagcta
    26581 tccagtcttt tcaatactag ggattagcta atagttctat gattttcaaa aaatttccaa
    26641 tcaattttct tgaaaccctt tcctactttt gatagactag tatctagttt ttgaaaaaag
    26701 gagaaagaaa atgaaaaaat ttgttgctga gttaatcggt acgttcatgc ttgtgttcgt
    26761 tgggacagga gctgttgttt ttggaaatgg tcttgatggc cttggtcacc ttggaatcgc
    26821 ctttgccttt ggtttggcaa tcgtggtggc agcctactca atcggaactg tttcaggtgc
    26881 tcacttgaac ccggctgttt cgattgctat gtttgcaaac aaacgtttgt catcttcaga
    26941 acttgtaaac tacatccttg gtcaggttgt tggagctttc atcgcttctg gcgcagtctt
    27001 cttcctcttg ggtaattcag gtatgtcaac tgctagtctt ggtgaaaatg ccttggcaaa
    27061 cggtgtcact gtctttggtg gtttcttgtt tgaagtcatc gcaactttct tgtttgtctt
    27121 gattatcatg actgtgactt cagaaagtaa gggcaatggc gcgattgctg gtttggtaat
    27181 cggtttgtca ttgatggcga tgattcttgt cggactgaag attactggac tttcagtaaa
    27241 cccagctcgt agcttggcac cagctgtctt ggtaggcggc gcagcccttc aacaagtttg
    27301 gattttcatc cttgcaccaa tcgctggtgg agttcttgca gcccttgttg caaaaaattt
    27361 ccttggaaca gaagaataat tgaaactcaa aaagccttgc tcctcatctt gaggaacagg
    27421 gctttttcgt atgatactct tcgaaaatct cttcaaacca cgtcagcttc accttgccgt
    27481 aggtatggtt actgacttcg tcagtttcat ctacaacctc aaaacagtgt tttaagctga
    27541 cttcgtcagt ttcatctaca acttcaaaac agtgttttaa gctgacttcg tcagttctat
    27601 ctgcaacctc aaaacagtgt tttaagctga cttcgtcagt tctatctgca acctcaaaac
    27661 agtgttttaa gctgactttg tcagttctat ctgcaacctc aaaacagtgt tttgagctga
    27721 cttcgtcagt tttatctaca acctcaaaca ctgctttgag caacctgcgg ctaacttcct
    27781 agtttgctct ttgattttca ttgagtatga ctttagcggt tgtcaatttt ctctggataa
    27841 aggtcgtgtt ggaagaggcg ttgttctgcc aagtcctcat acttagttcc ttgcttaccg
    27901 tagttgtagt aggggtcgat tgaaatgcca ccgcgcggag tgaattttcc ccagacttct
    27961 aaatagcgag ggtctagcaa gttgaccaag tctttcccga tggtgttgat acagttttcg
    28021 tggaaatctc cgtgatttcg gtagctaaat agatatagtt tgagggattt tgactcgaca
    28081 cagagcttgt caggaatgta ggaaatatga atcgtcgcaa agtctggctg agcagtgatt
    28141 tgtcccagca gagacatatc gaggatatgg tgacgaatgc cctgttcctt agcgatttct
    28201 ctagcaattt gaatttcgag gtgatgacgt tggccgtagg caaaggtgac agcttcgact
    28261 gtttcatagt gttgcataac ccagaaaagg caggttgttg aatcttgacc accactaaag
    28321 acgaccaagg ctgattgacg tttcatagta ctccttccaa aatgggaaat gttcagagca
    28381 tgcaaaaagc tcctattagg gagctaaaaa ataccaaatc gagttttttt agcgatggca
    28441 tatcccaaac atcgtaatat tctacttata tagtaaaatg aaataagaac aggacaaatc
    28501 gatcaggaca gttaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag
    28561 tttcaatcta ctatagtcta gcatattttt tgaaaaatgg caaagggcaa gaaaaaagag
    28621 accaaagaaa gtacttggtc tctcgtttga ttagctcaat tcagcaatga tggccttgat
    28681 ttgttctgct gtgtgaacac ctgcaacttg tttgacaact tggccgtctt ttttgaagag
    28741 aagagttgga atagacatga ttccaaaagc acgagctgtg tttggatttt catcaacgtc
    28801 cattttaacg attttcaaga catcttctga aagttcttca gacaatttgt ccaagattgg
    28861 accttgcata cgacatggac cacaccaagt tgcccagaag tctactaaga ccaaaccgtc
    28921 ttttgtttct tgttcgaatg ttgcatctgt aattgctttt gccattgtat ttctcctttt
    28981 tttagttata ttggcttaaa tcttgtttca tgagatagaa gaagatatct ccataagtcc
    29041 catggtagtc caaattatga cccttgtaag ttaatttttg gacagggtag tagtctgcga
    29101 cgccgataag gcaagcttgt tgcgaacgtt caaagtcttc ataagactcg aaagtcacag
    29161 ttctttcgtt cttgctggca tctatatagg taatttcaat catatttaaa actcctttgt
    29221 ttaatgctaa ctttatttta ctccttataa aagagaatgt caagaaaaat gattgcgcac
    29281 gcaacttttt ctaaaatcat cttaaatcaa gaaatccaaa cctgcttcca agctttcttc
    29341 gacagtcttt tgtagcgagg ccagtatctt ttgcccatca tttgtcaggc agataaaact
    29401 agagcgtcta tcttgatggc aacacatgcg actgagtaga ccgcaatttt tagcttccaa
    29461 gcgagccacc atcctagaaa ctgcgctcgg gctcagatga agcttatctg gcaggtcaat
    29521 ctggcgtaga gatttttctt cagccaagtc cagatagtag agcaggtaga actctttcaa
    29581 ggtcagactt tgctcgctct gttgggcaac ggtctcttcc aagagacttt caatttcttt
    29641 ctgacgccga ttgaagtcaa accatttttc caaataggtc atagtgtctc ctttcttttt
    29701 agagtcataa atagaagaaa gtccattaac gggcagtctc tgcgtcacaa gatgattgcg
    29761 catgcaataa ttatactact tttcaagaat gctggcaagc tctgtttttt agtggtttta
    29821 ttttttactg tctatatttt tggtaaaaat caacttttac ttggatgaag gttttggctt
    29881 cacgtaggag ttgaagaagg gtggcgcggg tttcaaattc ttctcttgtc ttgggcagac
    29941 tgcggttccg gaagacttcc agataacgtt caatttcatc tagcaaatca gaagcaggat
    30001 tggtctggct cagttgacct gcaatttttg aaaagagttg cgctaagatc aggctttcac
    30061 tggcggcaag gtgacaagtg ttaatctgtt gggccatgtt tctcaggata cgactttgtc
    30121 gctgtctcat ctcaaagtag tggatatggt agtcggtctg gtgaaagagg tggtcagagt
    30181 gatccaaata gaccagtctg agggcttctt tcaaaagcgt gtctaattct gctaccagct
    30241 gtgctcggtt gcgtccgtct cctctggata aatagtattt gaagcgctgg aggatatctt
    30301 ttaacttttc ttccaccagc gtgtggtagt gctggatttc ctcttctcgt gaaggcatat
    30361 agagattaac aagcaaggca aatcctgtac caatagcaaa gagaaggaat tcattgacta
    30421 gaaggtctgg agaggttgac tcttgaacca agagatggct aaccaaaaca gtgcttggtg
    30481 tgatgccaat ttcccagccc atcttgtagg ctaaaggaac gtagaaggcc agatagaggc
    30541 cgagactcca gatatgaaat ccgctcaagt gaaaagctag aacaccgata gccagagcta
    30601 gaagcataga aaaaagacga ttgcgagcca gttttaaagt acttctacgc gtatcagata
    30661 ggctcaagag agcgataatt ccagccgaaa ctgctgacga aagattgaga aaataagcaa
    30721 gcaggcaggc aagacaggta gctaagatga gcttggtcgt acgttggcta atagacataa
    30781 gaatttccta ataagttaga ataaaagcgt aaaagacaag acatgagcag gcttgccttg
    30841 atgagttatt ttttacgggt tgctgcgtat tcggcaacgg cggtaaagag gacatctgta
    30901 gaagagttaa gggctgtttc acatgagtct tggatgacac caatcacaaa accaacccca
    30961 acaatttgta tggcaatatc gttagaaata ccgaaaaggc tacaagcaac tgggataaga
    31021 aggagggaac ctccggcaat acctgaagca tcacaggatg agatagctgc taccacactg
    31081 aggacaaagg ctgtggcaaa gtcaacagga attccaagag tgttaactgc agcaagggtc
    31141 aaaaggttaa tggtaatcgc tactccagcc atattgatag tagaaccgag tgggatagaa
    31201 acagaatagg tatctgggtt gagtccaagg tcatggcaga gtttcatgtt gacaggaatg
    31261 ttagtcgcag aactacgagt gaaaaaggct gtcacaccgc tgacacggag gcagttccaa
    31321 actagagagt aaggattgcg tctcataaag aagaaggcaa tcaaagggtt gaccacaggg
    31381 gcaacaaaaa gcatagtcgt tactaatgga accaataaaa taccgtagtt ggcaaggctt
    31441 ccgactccct tgtcagaaat ggctttaaaa acaagaccaa ggattccaaa tggagccaga
    31501 ttgatgatcc attcgacaat tttagaagtc acgtcagcga tagtttttag caattcttta
    31561 ctatttttac tagcttctct catagcgatt ccaaaaatga ctgcccaaga taagattcca
    31621 atatagttag cagtaagcag ggcgttgact gggctgtcaa ccagtttgag caagaggttg
    31681 ctgaggacct gcccaatccc atctggtggt gcaatttcag tattggcact atttagggta
    31741 atttcaatag ggacgatgaa acttgctagt acagctacaa gagcagcggc gaaagtccct
    31801 atcataggat atacaagaaa acaacagttt tcatattgct atcttgtccc ttttgatgtt
    31861 gggaaagggc attggcaacg agggcaaaga ctaggatagg agcaacagct ttcagacctc
    31921 caacgaataa atccccgagt agcccaatcc ctgagagatt aggaagggtc agtcctagga
    31981 ttccccacaa agcataccaa tcaagatacg cttgacaagg cttgccttat tccaagcatg
    32041 aatgattctt ttcataataa tctccttttt gtgtagtgat tatgattata gtataaatga
    32101 tagacaaaat caagaatttt ctgtctattt tttgaatatt tatggagaat gagactgatg
    32161 aaaatatggt ataatgaaat aaaggagttt tatatgcaaa aatttattca ggcttatatt
    32221 gaaaagctag atgtgacaac cattatcgag aatattctaa ccaaggtcat ttctctttta
    32281 ctgcttttga ttgtatttta tattgctaaa aaaatgcttc ataccatggt gcagagaatt
    32341 gtcaaacctt ctctaaaaat gtctcgtcat gatgtcggac gccaaaaaac catctcacgt
    32401 ttactagaaa atgtgtttaa ttatacgcta tatttctttt tactctactg cattttgtcg
    32461 attttaggtt tgccagtttc tagtttgctg gctggagctg gtattgctgg ggtagcgatt
    32521 ggtatgggag cccaaggctt tctgtctgat gtcatcaatg gctttttcat cctctttgaa
    32581 cgtcaactgg atgtgggaga tgaggtcgtt ctgacaaatg gaccgattac tgtatcgggt
    32641 aaggttgtca gtgtgggaat tcgtacgaca cagcttcgta gcgaggagca agcccttcac
    32701 tttgtcccta accgaaatat cacagttgtt agcaatttct cacgcacaga ctagacctgt
    32761 tattttaagt aatttgtggt acaatagagg gagtttaata aggagaaaag atggttttag
    32821 aaaagcagtt gggcaatggt tgtacctgga tagacctaga cctaggaaag ttgaataaac
    32881 tagaagacct ttctgaaatt tacggtttgg acaaggaaac cattgaatac gcactggata
    32941 gaaacgagcg cgcccacatg gactaccacc gtgaaagtgg gacggttacc tttatctata
    33001 atgtcctaga cgtaaaaaag gacaaggcct actatgagac ttttcccatg acctttattg
    33061 tcgagcatcg tcgcctgatt accattagta ataccaagaa cgcctatgtc attgaacaga
    33121 tgactcgtta tctggagaac catgacacgc tttcgattta taagtttctc tttgccagtc
    33181 tggaaatcat cagcaatgcc tactatcctg tcattgagca gatggacaag agtagggatg
    33241 aggtcaatga cctcttgcgc cagcgaacta ccaagaaaaa cctctttgcc ctgtctgatt
    33301 tggagactgg tatggtttat ctgacggcag ctgccaaaca aaatcggatt ttgttagagc
    33361 atattcaagg tcatgccttg tatcgtagtt ttgatgagat tgagagagaa cagtttgatg
    33421 atgccatgat tgaggctcat cagctggtat ccatgacaga cctaatctct cagattttac
    33481 agcagctttc agcctcttac aacaatattc taaacaataa tctgaatgac aatttgacaa
    33541 ccttgactat catttcagtc ttgctagctg ttttggcagt cgtgacaggc tttttcggaa
    33601 tgaatgttcc cttaccttta acagataagc cccatgcttg gctctatatc agtttggcta
    33661 gtgcaggttt gtggattgtt ttatccttgt tactaaggaa aattgcgaaa aaaagttaag
    33721 aaaaggagcc agaatggcga ttgaaaatta tataccagat tttgctgtgg aagcagtcta
    33781 tgatctgaca gtcccaagcc tgcaggcgca gggaatcaag gctgttttgg tcgatttgga
    33841 taataccctc attgcttgga acaaccctga tggaacgcca gagatgaagc aatggctaca
    33901 tgaccttcgg gacgcgggta ttggcattat cgtagtgtca aataacacca aaaaacgcgt
    33961 tcaacgagca gttgagaaat ttgggattga ttacgtttac tgggccttga agcccttcac
    34021 atttggtatt gaccgtgcca tgaaggaatt ccactatgac aaaaaggaag tggtcatggt
    34081 tggtgaccag ctcatgacag atatacgagc agcccaccgt gcagggattc ggtcaatttt
    34141 agtcaaaccc ttggtccaac atgactcaat caaaacgcag attaaccgaa ctcgtgagcg
    34201 tcgtgttatg agaaaaatca ctgaaaagta cggaccgatt acatataaaa aaggaattta
    34261 actatggaag aaattctctg tattggttgt ggagcaacca ttcagacgac agataaagct
    34321 ggtcttggtt ttacccccca gtcggcactt gaaaaaggtt tggagactgg cgaagtctat
    34381 tgccaacgct gtttccgtct ccgccactac aatgaaatca cagatgtcca gttgacgaac
    34441 gatgatttcc tcaagctctt gcacgaggtg ggagacagtg atgctttagt ggtcaatgtc
    34501 attgatatct ttgattttaa tggatctgtc atcccaggtt taccacgttt cgtctcgggc
    34561 aatgatgtcc tcttggtagg aaataaaaaa gatatccttc ctaagtcagt taagtctggt
    34621 aagattagcc agtggctcat gaaacgtgcc catgaagaag gtcttcgtcc agtcgatgtg
    34681 gtcctaactt cagcacaaaa taaacatgcc attaaggaag tcattgacaa gattgaacac
    34741 taccgtaagg gccgcgatgt ctatgtggtc ggtgtgacca acgttggaaa atcaactcta
    34801 atcaatgcta ttatccaaga aatcacgggt gatcagaatg tcatcactac ttcacgcttc
    34861 ccagggacaa ccttggacaa aatagagatt ccgcttgacg acggatctta tatttacgat
    34921 acgccgggaa ttatccaccg ccaccagatg gctcactatt tgacggccaa aaacctcaag
    34981 tatgtcagtc ctaaaaagga aatcaagcct aagacctatc agcttaatcc tgagcaaacc
    35041 ctatttttag gtggtttggg acgctttgac tttataacag gagaaaagca aggatttact
    35101 gctttctttg acaatgaact caaactccat cgtagcaagc ttgaaggagc tagtgctttc
    35161 tacgataagc acctgggaac tcttctgaca ccaccaaata gcaaggaaaa agaagatttc
    35221 ccaaggctag tccagcatgt ctttaccatt aaagataaga cagacctagt catctcaggc
    35281 ctaggctgga ttcgtgtaac aggcacagca aaagtcgccg tctgggcacc agaaggcgtc
    35341 gccgtcgtca cacgaaaagc aattatttaa aacaaaatcg ctgagcgaac aaagtgagct
    35401 catatagcga tagttattgc cgtggtgtga ttgccaatct gtagattggc aaggggcaca
    35461 attgagacca aggctcaatt gtgaggtcag gaaatccatt tttcaaagat gaaatctttg
    35521 gaaaattagt tccgaccgtc cctcaccacc taaaataact atcaaaaaac aaggaagaaa
    35581 attatgtcat taacatcaaa acaacgtgcc ttcctcaaca gccaggcaca caccctcaaa
    35641 cctatcatcc aaatcgggaa aaatggactc aacgaccaaa tcaaaaccag cgtccgtcaa
    35701 gctcttgatg cgcgtgaatt aatcaaggtt actctcttac aaaacacaga tgaaaacatc
    35761 cacgaagtag ctgaaatttt ggaagaagaa atcggtgtgg atacagtcca aaaaatagga
    35821 cgcatcttga ttttgtttaa acaatctagc aagaaagaaa atcgcaagat ttctaagaaa
    35881 gtcaaagaaa tctaagaccg aaactccaaa taactgtttt catagagaaa taaaggggac
    35941 tagcctatga caatcgaact attgactccc tttaccaagg tagagttgga gccagaaatc
    36001 aaggagaaaa aacgcaaaca agttgggatt ttagggggga attttaaccc tgttcacaat
    36061 gcccatctta ttgttgcgga tcaagtacgg caacagttgg gactggatca agttctgctc
    36121 atgcctgaat accaacctcc tcacgttgat aaaaaggaaa ccatccctga acaccatcgt
    36181 ctcaagatgc ttgagttggc aattgaggga attgacggcc tagtcattga aaccattgag
    36241 ttggagcgca agggtatttc ctacacctac gacaccatga agattttgac agagaagaat
    36301 ccagatacgg attattactt tatcatcggt gccgacatgg ttgactatct gcctaagtgg
    36361 taccgaattg atgaactggt tgacatggtt cagtttgtgg gggttcagcg tccacgctac
    36421 aaggtaggga cttcctatcc agttatctgg gtggacgtac cgctcatgga tatctcgtcc
    36481 agcatggtgc gggacttcct tgcccaaggt cggaaaccca actttctcct acctcagcca
    36541 gtgctagact acatcgagaa ggaggggctc tactgatgtc ctatcaagac tatatcaact
    36601 gctcccgtga ggccttgttg gaaaaaatgg cagagcttct acctgagaaa cgtctaaccc
    36661 attgtctagg tgtggagcgt gccgctatgg aattagctca gcgctttggt gtagatgttg
    36721 agaaagcaag tctagcaggt cttcttcatg actatgctaa aaagttgtca gatcaggaat
    36781 ttctagcctt gattgaccgt taccagctag accctgacct caaaaactgg ggcaacaatg
    36841 tctggcatgg tatggtcgga atttacaaaa ttcaggaaga tttggatttg catgattctg
    36901 aaattctgcg agccattgaa attcatacag tcggagctgg tcaaatgaca gacctagata
    36961 aggtcatcta cgtcgcagac tatatcgagc acaatcgggc atttcctgga gtggatgtgg
    37021 cgcgtgagat tgcaagtcta tcgctcaata aggcggtggc ctacgaaaca gctcgtaccg
    37081 tggagtatct agctcatcag ggattcccca tctatcccca aacccttgaa acctataacg
    37141 cctttgtgca ctatttgaaa gaggactaaa tgaagacggc ttttataatc attgatgttc
    37201 agaatgtttt agtagaaact gggttccaga caaaaagtct attggaaaaa atttcttatt
    37261 tacaaaacca ggctagaagc aagaatattg aaattatcta tgttcaacat attgagaact
    37321 ctgaagctca aacatcagaa gattggcagt tatctgcgct tttaaatcga aaacctgctg
    37381 aaaaggtctt tcagaagaag tataacagta ttttcaaaga aactggctta aaagaatact
    37441 tggataagca ggggattgaa aaattagttt tatgtggtat gcagacagaa tattgtgtgg
    37501 atacctctgt caaggttgcc tttgaatatg gctatcagct tattgttcca gaaggtgctg
    37561 tcacaacctt tgatggggat gacattccag cagaaacgat taatgaattt tatgaggaca
    37621 tttgggagga gcgctttgca gatgttctag attacaaaca tattttctaa aaagaggatt
    37681 aaatgaacga aaaagaatta ctagaactag tcgtgaaagc ggctgatgag aaacgtgcgg
    37741 aggatatcct cgcacttgat gtacaagatt tgactagtgt gacggactac tttgtcatca
    37801 ctagctcaat gaatagccgt cagttggacg ctatcgcagc taatatccgt gaaaaagtag
    37861 ctcaagcagg ctttaaaggt agccatgtcg aaggcgatgc agctggaggc tgggtcttac
    37921 tggacctcgg tgctgttgtc gtgcatatct tttcagaaga aatgcgtgcc cattataatc
    37981 tagagaagct atggcatgag gcgaattcag tagatatttc agaagctctt gcttagaaga
    38041 tgaactcagt tgtagtcaac tgggtttctt tgcttatttt agaaaaattg atagaaaggt
    38101 aaagggcctc gtgtttgttt catttcgaaa ctgaacacga gctaaaagct gagataaaaa
    38161 gtaactttct ttgtatctga cgatagggaa gaaagtttcc tatgtactct ttgcttttaa
    38221 ggctctttgt atcttagaaa ggatttgaac ccgtcctgta attctcggaa aatagatagc
    38281 cttccttgga gctcggctcc atcgtaaggc tcctaatttt ctatcgaatt acgggcggac
    38341 ttggtatcat gttttatggc gacttatgaa acctttgcgg cggtctatga tgcggtcatg
    38401 gacgatagtt tatacgacaa atggacgaat ttttctctgc gtcatttgcc taagaccaag
    38461 gagagaaaga aactcttgga attggcttgt gggacaggaa ttcaatcagt gcgcttctct
    38521 caggctggtt ttgatgtgac tggacttgac ttgagtgcgg atatgttgaa gattgcggag
    38581 aagagagcaa cttcagccaa gcaaaagatt gcttttatag aaggtaatat gctgaatttg
    38641 tccaaggcag ggaaatacga ttttgtcacg tgttattcgg actctatctg ctatatgcag
    38701 gatgaggtgg aagtagggga cgtctttaag gacgtgtaca atgcgctgaa tgaagaggga
    38761 gttttcatct ttgacgtgca ctcgacctac cagacagatg aagtattccc tggctattcc
    38821 taccatgaaa atgcggaaga ttttgccatg ctttgggata catatgagga cgaagctcct
    38881 cactccatcg tgcatgagct gactttcttt atcaaggagg ctgacggttc ctttagtcgc
    38941 cacgatgaag tacatgagga gaggacctat gagatcttga cctatgatat cttgctggaa
    39001 caggctggat ttaagtcctt caaactctat gcagactttg aggataagga gccaacagaa
    39061 actagcaccc gttggttttt tgtggcgcag aagtaggaga acatcatgac catcacaggt
    39121 attatcgcag agttcaatcc ttttcataat ggccataaat acctgctgga tcaggcagag
    39181 ggactgaaaa ttgttgccat gtcagggaat ttcatgcagc gtggagagcc tgctattgtg
    39241 gataagtgga caagggccca gatggcgctg gaaaatggcg cagacttggt agtggaattg
    39301 ccctttttag tcagtgttca ggcagctgat ttctttggtc aaggagctgt ggatatcttg
    39361 gatcgcttgg gcattgatag tctagttttt gggacagagg aagttcgaga ttatcagaaa
    39421 atcgctgact tatacacaga gaaaggtact gagatggaga aatttgtgga aaatctgcct
    39481 gattcccttt cctatcccca gaaaacccaa gctatgtgga aggaatttgc tggtcttgat
    39541 ttttcaggta atacccccaa tcatgttctt gctctggcct atgccaaggc ggttgcagga
    39601 cggaatatca agctgcatcc gattcagcgt cagggggcag gttaccattc tgtgaataaa
    39661 gatgtggact ttgcctcggc gacagccctc cgtcaacatc agaaggacca agatttctta
    39721 gaacgtttta tgccttctgt tgccctattt gagcaggcca gtaaggtgat ctgggaagac
    39781 tattttccct tgctccgcta tcaaatcttg tcaaatcccg acctaaccac catctatcag
    39841 gtcaatcaag aaatggctgt gcgcattaaa gaagctatta aaacagccca gtctgtggaa
    39901 gaattggtcg agttagtgac taccaaacgt tacaccaagg cgcgtgtcag acgcctcttg
    39961 tcctatatct tggcgcaggc tagagaaaat gtcttgccag aagccattca tgtccttgga
    40021 tttactgaaa aaggcaggca acatctcaag tctttgaaag gtcaggtcag tctagtcagc
    40081 cgaattggca aagaaccttg ggatgctatg acccaaaaag cagaccagat ttaccaacta
    40141 ggaaatctaa gtatagcaca acagaatttt ggaagagtgc cgattagaat agaaacaaac
    40201 taagtctacc gaaaggtgga ctttttgaga ttttttacga ataatactct tcgaaaatca
    40261 aattcaaatc gcgtcaacgt cgccttgccg tactcaagta cagcctgcgg ctagtttcct
    40321 agtttgctct
//
LOCUS       DBEJJV010000015        39674 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.015, whole genome shotgun sequence.
ACCESSION   DBEJJV010000015 DBEJJV010000000
VERSION     DBEJJV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.015"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..928)
                     /locus_tag="ACL3GT_000912"
     CDS             complement(<1..928)
                     /locus_tag="ACL3GT_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate hydrolase"
                     /protein_id="HGR0516594.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPQVVEKSSLE
                     KKYEEAKAKADTAKKDYETAKKKAEDAQKKYDEDQKKTEEKAKKAEEAAKEVDDASLA
                     VQKAYVEQRKAQEEKNKHSGNPEYAKKLAEADKKITEETTKLTDAQTKFQSVQAMVVP
                     EPEQLAETKKKAEEAKAEEKVAKRKYDYATLKVVLAKKEVEAKELEIEKLQYEISTLE
                     QEVATAQHQVDNLKKLLAGADPDDGTEVIEAKLKKGEAELNAKQAELAKKQTELEKLL
                     DSLDPEGKTQDELDKEAEEAELDKKADELQNKV"
     gene            complement(1214..1753)
                     /locus_tag="ACL3GT_000913"
     CDS             complement(1214..1753)
                     /locus_tag="ACL3GT_000913"
                     /inference="COORDINATES: protein motif:HMM:NF037419.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HGR0516595.1"
                     /translation="MLFYFEKIWSLSLKLLDCILDYQERFNRKACQVSTNYKYLETFK
                     VNFCLTDLHHLFGLHKITRDYASQTKPAIQAGVFILEDFRNILLYNDVIERISLYEFI
                     GDIFYFKITSCCIVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFT
                     SAKKYAKVRKTDVKEMKWL"
     gene            complement(2176..2373)
                     /locus_tag="ACL3GT_000914"
     CDS             complement(2176..2373)
                     /locus_tag="ACL3GT_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516596.1"
                     /translation="MKHFFAGIGEIKLVGYLLYICVGLAPLFHIYVIGSELSFVKIVL
                     SILGVIFVSMLTIARIYRTFL"
     gene            complement(2852..3580)
                     /locus_tag="ACL3GT_000915"
     CDS             complement(2852..3580)
                     /locus_tag="ACL3GT_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516597.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIVYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            complement(3577..3909)
                     /locus_tag="ACL3GT_000916"
     CDS             complement(3577..3909)
                     /locus_tag="ACL3GT_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR0516598.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICVALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            complement(3965..4867)
                     /locus_tag="ACL3GT_000917"
     CDS             complement(3965..4867)
                     /locus_tag="ACL3GT_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516599.1"
                     /translation="MMRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(4873..5190)
                     /locus_tag="ACL3GT_000918"
     CDS             complement(4873..5190)
                     /locus_tag="ACL3GT_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516600.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGDWNTFKNNIKGLARASSGFRF
                     AARETGLWAAIWSTRVYSYTYVVSAFAPILGSVAAVNAALAVIGGISVAGITYALWTR
                     KFY"
     gene            complement(5335..6687)
                     /locus_tag="ACL3GT_000919"
     CDS             complement(5335..6687)
                     /locus_tag="ACL3GT_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HGR0516601.1"
                     /translation="MKLYNKSELRYSRIFFDKRPPAFAFILIISTAIILSGALVGAAY
                     IPKNYIVKANGNSVITGTEFLSAIGSGKVVTLHKSEGDMVNAGDVIISLSSGQEGLQA
                     SSLNKQLEKLRAKEAIFQKFEQSLNEKYNHLSNSGEEQEYYGKVEYYLSQLNSENYNN
                     GTQYSKIQDEYTKLNKITAERNQLDADLQALQNELLQLQQQGDSPSLSDTTSADNKAK
                     LETKISEITTKIEALKTNITSKNSEIDSQQSNIKDMNRTYNDPTSQAYNIYAQLVSEL
                     GTARSNNNKSITELEANLGVATGQDKAHSILAPNEGTLHYLLPLKQGMSIQQGQTIAE
                     VSGKEKGYYVEAFVLASDISRVSKGAKADVAITGVNSQKYGTLKGQVRQIDSGTISQE
                     TKEGNISLYKVMIELETLTLKHGSETVVLQKDMPVEVRIVYDKETYLDWILEMLSFKQ
                     "
     gene            complement(6684..7151)
                     /locus_tag="ACL3GT_000920"
     CDS             complement(6684..7151)
                     /locus_tag="ACL3GT_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0516602.1"
                     /translation="MAKLEVKDNKKLVLKSVICKKLHDTKVEDVDQEINKFHQHLQLL
                     KAQIFGPLIVKSCGTTIHDDGLITTDFEFYIQAHNAQQYSNIYDVQDSISVPYCLYVR
                     FEDSPEYLQYAYSKLDLYVYENDIQTDGIVYTVYVNSSPEKMVVDIFRPIVSL"
     gene            complement(7144..9363)
                     /locus_tag="ACL3GT_000921"
     CDS             complement(7144..9363)
                     /locus_tag="ACL3GT_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HGR0516603.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     RNSKFYVADPASGIRKMSSDELGEIYQGITLFMVPNSDFERGKLKGKGLLDLFGRLIF
                     NQKGLISTVILASFVLSIIGILSSLFSKVIMDEVIPYALKNSLYMFLIVFGIVSFLQT
                     LLSAFRQHVLLFLSRKIDIPVLMGYYDHIIHLPYSFFGSRRVGDVLTRFQDAMTIKNV
                     FTSVSISLVMDITLSVISAVVLWTINQSLFLILVFMVIVNIILIYCFKKPYKKINHEQ
                     MEANGLLNSQLIESIRNIDTIKSQHDEEQRLNKIEEKFVHTLEIGYKEGVLQNIQSTI
                     SSMTSTMGGLLFMGVGALFIIDGKMTIGDLLVFQTLSQYFTEPIQNLVGLQLTFQEVQ
                     VAVSRLQELMEVDREDIALDYSIRDFTLCDDIEFKDVTFAYGSRPPVIKDFNLRIKQG
                     EKIAFVGESGAGKSTLVRLLLRFINPSEGKIRIGENDLSDLDYGKLRKKISYIPQTIE
                     LFTGTIIDNLKIGNPSVTYEDMVRVCRIVGIHDTIQRLQNRYGSFVEEGGQNFSGGEK
                     QRLAIARALLSKADLYIFDEATSNLDSFSEQIIQDLIFNKIMDKTTIVVAHRLSTILR
                     CDKICFLENGTIMEYGTHEELMAKNGKYARMVGLQSVQVNQQIQSQAVLDTEEVTYG"
     gene            9829..10692
                     /locus_tag="ACL3GT_000922"
     CDS             9829..10692
                     /locus_tag="ACL3GT_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0516604.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILSHLKK
                     EVEIYYQAKER"
     gene            complement(10981..12372)
                     /gene="argH"
                     /locus_tag="ACL3GT_000923"
     CDS             complement(10981..12372)
                     /gene="argH"
                     /locus_tag="ACL3GT_000923"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004056 - argininosuccinate lyase activity
                     [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HGR0516605.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDVIGSLAH
                     VQMLGQTGILSLEESEKIQVGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGYVLDKLAHLKGVLLDLAENHVATIMPGYTHL
                     QHAQPISFAYHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKQPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TTGSSIMPQKKNPDMAELIRGKTGRVYGHLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREAHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(12401..13598)
                     /locus_tag="ACL3GT_000924"
                     /pseudo
     CDS             complement(12401..13598)
                     /locus_tag="ACL3GT_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
     gene            complement(13615..14421)
                     /locus_tag="ACL3GT_000925"
     CDS             complement(13615..14421)
                     /locus_tag="ACL3GT_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0516606.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLVTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYSVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(14628..15269)
                     /locus_tag="ACL3GT_000926"
     CDS             complement(14628..15269)
                     /locus_tag="ACL3GT_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516607.1"
                     /translation="MIELENITKTIGGKVILDRLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSATLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            complement(15266..17374)
                     /locus_tag="ACL3GT_000927"
     CDS             complement(15266..17374)
                     /locus_tag="ACL3GT_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HGR0516608.1"
                     /translation="MKKISHLCMLLLLLCTTFFVLNVNVTREIVRIQEMGKTTYSFDL
                     YLKDVTKPTETILQFFEEVASQDKVSIIKVDNGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLFSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSLPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     ALASRMEKRSLVELLKGGIL"
     gene            complement(17429..17710)
                     /locus_tag="ACL3GT_000928"
     CDS             complement(17429..17710)
                     /locus_tag="ACL3GT_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HGR0516609.1"
                     /translation="MNHEKISVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFGY
                     SDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            18122..18448
                     /locus_tag="ACL3GT_000929"
                     /pseudo
     CDS             18122..18448
                     /locus_tag="ACL3GT_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(18500..19087)
                     /locus_tag="ACL3GT_000930"
     CDS             complement(18500..19087)
                     /locus_tag="ACL3GT_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0516610.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            19329..20000
                     /gene="sdaAB"
                     /locus_tag="ACL3GT_000931"
     CDS             19329..20000
                     /gene="sdaAB"
                     /locus_tag="ACL3GT_000931"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HGR0516611.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20009..20881
                     /gene="sdaAA"
                     /locus_tag="ACL3GT_000932"
     CDS             20009..20881
                     /gene="sdaAA"
                     /locus_tag="ACL3GT_000932"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HGR0516612.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            20903..21535
                     /locus_tag="ACL3GT_000933"
     CDS             20903..21535
                     /locus_tag="ACL3GT_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0516613.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            21585..21755
                     /locus_tag="ACL3GT_000934"
     CDS             21585..21755
                     /locus_tag="ACL3GT_000934"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516614.1"
                     /translation="MKIKEQTRKLAAGCSKHCFKVVDGTDEVSSKHCFEVVDRTDEVS
                     NIYIRQGDVDVV"
     gene            complement(21841..23691)
                     /locus_tag="ACL3GT_000935"
     CDS             complement(21841..23691)
                     /locus_tag="ACL3GT_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HGR0516615.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(23733..24890)
                     /locus_tag="ACL3GT_000936"
     CDS             complement(23733..24890)
                     /locus_tag="ACL3GT_000936"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0516616.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENVEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            24948..26114
                     /locus_tag="ACL3GT_000937"
     CDS             24948..26114
                     /locus_tag="ACL3GT_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HGR0516617.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            26253..26579
                     /locus_tag="ACL3GT_000938"
     CDS             26253..26579
                     /locus_tag="ACL3GT_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HGR0516618.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            26566..27159
                     /locus_tag="ACL3GT_000939"
     CDS             26566..27159
                     /locus_tag="ACL3GT_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HGR0516619.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            27152..28063
                     /locus_tag="ACL3GT_000940"
     CDS             27152..28063
                     /locus_tag="ACL3GT_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HGR0516620.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            28126..29190
                     /locus_tag="ACL3GT_000941"
     CDS             28126..29190
                     /locus_tag="ACL3GT_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6574 domain-containing protein"
                     /protein_id="HGR0516621.1"
                     /translation="MKQEWFESNNFVKTTSKNKPEEQAQEVADKAEETIADFDTPIEK
                     NTQLEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(29262..30122)
                     /locus_tag="ACL3GT_000942"
     CDS             complement(29262..30122)
                     /locus_tag="ACL3GT_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 family protein"
                     /protein_id="HGR0516622.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDDSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILV
                     QDFKTLAQEK"
     gene            complement(30244..31230)
                     /locus_tag="ACL3GT_000943"
     CDS             complement(30244..31230)
                     /locus_tag="ACL3GT_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HGR0516623.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(31502..32977)
                     /locus_tag="ACL3GT_000944"
     CDS             complement(31502..32977)
                     /locus_tag="ACL3GT_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0516624.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(33235..34158)
                     /locus_tag="ACL3GT_000945"
     CDS             complement(33235..34158)
                     /locus_tag="ACL3GT_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0516625.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(34172..35101)
                     /locus_tag="ACL3GT_000946"
     CDS             complement(34172..35101)
                     /locus_tag="ACL3GT_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516626.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(35420..35641)
                     /locus_tag="ACL3GT_000947"
     CDS             complement(35420..35641)
                     /locus_tag="ACL3GT_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516627.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTAAELIDNLKEVIAKLKANA"
     gene            complement(35595..35855)
                     /locus_tag="ACL3GT_000948"
     CDS             complement(35595..35855)
                     /locus_tag="ACL3GT_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516628.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALTDDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            complement(36281..36436)
                     /locus_tag="ACL3GT_000949"
                     /pseudo
     CDS             complement(36281..36436)
                     /locus_tag="ACL3GT_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 transposase-related protein"
     gene            complement(36622..37233)
                     /gene="rpsD"
                     /locus_tag="ACL3GT_000950"
     CDS             complement(36622..37233)
                     /gene="rpsD"
                     /locus_tag="ACL3GT_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HGR0516629.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(37428..38480)
                     /locus_tag="ACL3GT_000951"
     CDS             complement(37428..38480)
                     /locus_tag="ACL3GT_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0516630.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(38477..39175)
                     /locus_tag="ACL3GT_000952"
     CDS             complement(38477..39175)
                     /locus_tag="ACL3GT_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0516631.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGCETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(39342..>39674)
                     /locus_tag="ACL3GT_000953"
     CDS             complement(39342..>39674)
                     /locus_tag="ACL3GT_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0516632.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
BASE COUNT        12122 a         8396 c         6749 g        12407 t
ORIGIN      
        1 caactttatt ttgaagttca tcagcttttt tatccaactc agcttcttct gcttctttat
       61 ctaattcatc ctgagtctta ccttcaggat caaggctgtc aagaagtttt tcaagttctg
      121 tttgtttttt tgctaactca gcttgtttag cgtttagctc agcttctcct ttttttaatt
      181 tagcttctat aacttctgtg ccatcatcag gatccgcacc agcaagaagt tttttcaaat
      241 tatctacttg atgttgagca gtagcaactt cttgttccaa agtagaaatt tcatattgaa
      301 gtttttcaat ttcaagttcc ttagcctcta cttctttctt cgctagtact acctttagag
      361 ttgcataatc atattttctc ttagctactt tttcttctgc tttagcttct tctgcttttt
      421 tcttagtctc agccaactgc tctggctcag gaactaccat tgcttgaaca gattgaaatt
      481 ttgtctgagc atcggttagt ttagtcgtct cctcagttat ttttttatct gcttctgcta
      541 attttttagc gtactctgga tttcctgaat gtttattttt ttcttcttgt gcttttcttt
      601 gttccacata agctttttgc accgctaaac tagcatcatc tacttcctta gcagcttctt
      661 ctgctttttt cgctttctct tcagttttct tctgatcctc atcatatttc ttctgagcgt
      721 cttctgcttt ctttttagcc gtttcgtaat ctttcttggc agtatcagct tttgcttttg
      781 cttcctcata tttcttctct aatgaagatt tttcgacaac ttgtggagct tcttctgctc
      841 ttacaaaagt aggctgagac gtaacaaaac cagcccctaa gatagcgacg ctggctagac
      901 ttgttaaaat catttttttc ttattcatct aaatttacct cttttctgat agtcattttt
      961 agactatact tatattaagt atactccccc cgtaaatatt tgtcaaatgt tttatattac
     1021 atttttatta caaatttcta tatcataagc ttctactcca aaaagataaa gacactactt
     1081 ttgccctttt cgattctctt tttaaacata gcatcatctt ccttcattcc tataaaaaca
     1141 tttccgatga gagagcttgt tttttaattt cgttaaacaa caaaaaacgc aagcttaagc
     1201 ctgcggacaa tctttatagc catttcattt ctttcacatc tgttttacga actttagcat
     1261 atttcttagc gcttgtaaaa tgtagagtaa ctggtttaaa tactccgctt ttgtctcttc
     1321 gtaaacctaa aactgcggat cttttatttt tatcctcaaa aaatatgacg tccaatttca
     1381 tagtattttt agataaatcc ttagctacga tgcaacaact tgttatttta aaatagaaaa
     1441 tatcacctat aaactcatat aaagatatcc tttcgattac atcattgtac aataggatat
     1501 ttctaaaatc ttctaaaata aaaacaccag cttgaatagc aggttttgtt tgactagcat
     1561 aatctcgtgt gattttgtgt aagccaaata aatgatgtaa atcagtcagg caaaaattca
     1621 ctttgaaagt ctctaaatac ttataattcg ttgatacttg acatgctttt ctattgaatc
     1681 tttcttgata atccaaaata caatcaagta atttcaacga caaactccat attttctcaa
     1741 aataaaaaag cacggggcag ttctcactac tgcccaaagt ggttgattag agtcggcttc
     1801 tctaactccc tatgttgtgc ttattaggct tatcgcaagg gaacagtttt tagctctgcc
     1861 aagccacata gtgtgcttac tactatgtgt ccatgtcacc atgaattgcc gaacggttta
     1921 acgagaaagt atagtagatt gaaacaagat gtgaacaaat cgattaggaa agtcaaatta
     1981 atttctagaa atattttaac agtcataacg gactattcca gattcaatct actatattac
     2041 ttttaggttt atcccaactc aattatgaca tctttttttc aaaagtcaat atatctcact
     2101 cttttcaacg acaagaaaga ggctgataat cgaccaacct ctgtttttag atacagttca
     2161 agtccaaact attctttata gaaaagtccg ataaattcga gcaatagtta acatacttac
     2221 aaatataact cccaaaatag ataacactat tttcacaaaa ctcagttccg aacctatgac
     2281 atatatatga aaaagagggg ctagtcctac acatatatac aataagtagc caacaagttt
     2341 tatctcacca attcctgcaa aaaaatgttt catgtaacga ttctccattt actctattaa
     2401 atcaatttta ttttagacta tcataacaca atcacctctt caataaaaac cattggcgaa
     2461 atactattct gaagcattga tagctcagat ttctcagaat agagctgtcc taactatcga
     2521 gcagctcaaa tacatatata tgagcaattc taagtttaga attgctataa aataaatgtt
     2581 tccaggctat tctaagtctt tgactgctta aaattttacg ttctgaagga ttctaaagct
     2641 agaacagctc aaaatcacga gaactaaggt attcgaaact tcagagtaat acaatcccca
     2701 taggaattct ccattcttat taagcatgat taaaatgtaa tcctaacaag tgatcctcga
     2761 ctgtgtttgt agcacttagt tacctagata agactatttc cctttatcat atctgatttt
     2821 aagccgttct aagatttaac ctatgtttct attacttgct atttttaaat aattcgaatt
     2881 ccttttcttt gataaatgga actgaaaaat tagaaaaaag aagtaaaacc gaaaacaaat
     2941 agcctgcttt ttgaatcact aaaagatatc ctaaaaataa gtaaactata acatccaatg
     3001 cgaaaagaaa aaatattctc ctcttcatta aagtacttgt gtcaaataat ctgatgaata
     3061 aaaattttat cgtagtatct acacaaattt ttatcaaaaa gataagagcc aatacacgat
     3121 tatcaactgt accgtaaaga atagatggaa atatagttaa tataaaacta gaaatctcta
     3181 aatattttat ccaaggagat tgagacacct tgcttctaaa ctgactaatt ttcttatatt
     3241 cgttagtcaa tttagtagca aaatcttccc caattaaatg aaagattgct aactctagga
     3301 taaaaacact tattaatacg gtataagtca aaaaactttc tgggaaaaac ttattgatta
     3361 aaatggggaa actcattaac agaatcgaat ttatggctag acagatagat actattttat
     3421 ttttcacaga atatagaggt agtgatacta ttgagtagat aaaagctaaa aaaataagca
     3481 aaaaatactc cgtgtcattt ataatcgccc tgaatgataa aaatatatac atccaacata
     3541 cgataatatg tatttttcga atcttatcta cattattcat cttactgtcg cagatataaa
     3601 tccatcccaa ggataagggt tcccgctaat atcacaacct ctattaagag caccatatcc
     3661 aatacagtaa gctatttttc ctgctgctgc accaataagc cagcctccaa gacctccaac
     3721 cttaatatag tttattagtt ttttggttaa aactgcagct ccagctaatg ctataaaagt
     3781 tcctgaactc atagctaaag ctacgcaaat tccttgacaa gcacgcttgc ttaaataagc
     3841 tcccccatca agatacatca tttcttcttc atcaatcaca acataattat ttggtaatac
     3901 aagttccatt tgttttctcc tccttagttg aaattgtttc atttgtttta caaataggac
     3961 gaacttaaac tatcttttta ttactcagta ataatttccg agatttcatt ttatgatact
     4021 ctctattcat acagaaatca aaattttgcc ttaaccaact tgtataatag aaaaaatcta
     4081 attgatttat tctgatgagc tgtattctaa ttttatcaac cttttcttgc cagttgttat
     4141 tgttactaat agaaatctca tacagcagta actcgacaag acctgtacac agaagggtgt
     4201 tatgagaatc ttcaatttta ctcagaatat cctcaaaaag ttcactatcc gttaaaaagg
     4261 tggattgatt catcgcatca tacagctgaa gagacattaa gtcagaataa ctgagatctg
     4321 atttttgtat tttatccttt aacgtatttg tcaaatcact ttcaaacgaa tcttcttttt
     4381 cccatttatt ttgattgaaa agaaattccg tcttattaaa aacgagatga ttgatatcca
     4441 ttatagtcca aaaaaatatt gtagtaagca taatgatgac aaaaggaatt tttaaaataa
     4501 atactaggat aatagcaatt tcaagaataa aactccatat aatcctagat cttaaatcat
     4561 caggcgacaa acttttacga tggaatgaaa aatagggcga gaacctcaca tttactttct
     4621 tcctgcctat aaaaataaaa ggaaaaatcg taataagagc ttctttcttg tacaaatctt
     4681 tcaatgcgta tagtatgtct aaaactattt ttgataaaat caaactacag aaagcaagac
     4741 tcatactaat cacaaaatca aggggagatt ctagattcaa tagtaagtta ttcactagga
     4801 catgcaactc tagccacaag acaaaaagag ggagcattag taagaaaaca attagtttac
     4861 gcattataac aattagtaaa atttacgcgt ccataaagca tacgtaattc ctgcaactga
     4921 aatacctcca attacagcca atgccgcatt aacagctgct actgacccta gtattggagc
     4981 gaaagcagaa acaacataag tataagaata cactcttgta gaccatattg cagcccataa
     5041 accagtttct cttgcggcaa acctaaatcc tgaggaagct ctcgctaaac cttttatatt
     5101 atttttaaat gtgttccagt ctcccccatc aaggtacatc atctcttctt catcaatcac
     5161 aacataatta tttggtaata caagttccat ttgttttctc ctttttatta agcatggtta
     5221 ggatggtttc ctaacaagta atcgtcgtct gtgtttctat cacttagcta cctagataag
     5281 atatcctttc tctaccttat ttgtttttat aggttaccta aggtttaaaa ccaattattg
     5341 cttgaaactt aacatttcta aaatccaatc aagataggtt tctttatcat agacaatccg
     5401 cacttcaact ggcatatcct tttggaggac gactgtctca cttccatgtt ttagagttaa
     5461 ggtttctaat tctatcatga ctttataaag actaatattg ccttctttcg tttcttggga
     5521 aattgttcct gaatcaatct gtctgacttg tccctttagt gttccatatt tttgactatt
     5581 tacaccagta atagcaacat cagcttttgc tcctttcgaa acacgagaaa tatcactcgc
     5641 aagtacaaaa gcttctacat agtaaccttt ttctttccct gaaacttctg ctatcgtttg
     5701 cccctgctga atagacattc cttgtttcaa aggtaacaga taatgcagag taccttcatt
     5761 tggcgctaat atactatgag ctttatcttg acctgttgcc actccaagat tagcctcaag
     5821 ctctgtaata cttttattgt tgtttgaacg agcagtacct aactcactaa ctaattgagc
     5881 ataaatatta taagcctgag aagttggatc attataggta cggttcatat ccttaatatt
     5941 gctttgttga ctatcaatct cgctattctt agaagtaata tttgttttta atgcttcgat
     6001 ttttgttgtt atttctgata tcttagtttc taacttagct ttgttatcag ctgatgtcgt
     6061 atctgataga gaaggtgagt ctccttgctg ttgaagttga agcaattcat tttgtagagc
     6121 ttgcaagtcg gcatctaact gatttctttc agctgttatt ttattcaact tcgtatattc
     6181 atcctgaatc tttgaatact gggtaccatt attataattt tccgaattta actgagatag
     6241 gtagtattca actttcccat aatattcctg ttcttcacca gaattagata aatgattgta
     6301 tttctcattt aatgattgtt caaatttttg aaagatagct tcttttgcac gtaacttctc
     6361 caattgttta tttaaagagc tcgcttgtaa accttcttgc ccacttgata acgaaataat
     6421 gacatctcca gcatttacca tatctccttc tgacttatgt aaagtaacta ccttccctga
     6481 accaattgct gataggaact ctgtacctgt tataactgaa tttccattcg cttttacaat
     6541 atagtttttg ggtatataag ctgcgccaac caatgcaccg cttaagataa tagcagttga
     6601 aataatgaga ataaacgcaa aagctggtgg tctcttatca aagaaaatac gagaataacg
     6661 taattctgat ttattatata atttcatagg cttacaattg gtctaaaaat atctactacc
     6721 attttttcag gagaagaatt aacataaact gtatagacaa tcccatccgt ttgaatatca
     6781 ttttcataga catatagatc caatttagaa tacgcatact gtagatactc tggactgtct
     6841 tcaaaacgaa catataaaca atatggaaca gagatagaat cctgtacatc ataaatgtta
     6901 ctgtactgtt gagcattatg agcttgaata taaaactcaa aatcagtcgt tattaatcca
     6961 tcatcatgaa tagtagtacc acaacttttt acaattaatg gaccaaaaat ttgtgctttt
     7021 aacaactgca aatgttgatg aaatttatta atttcctgat ctacatcttc tacttttgta
     7081 tcatgtaact ttttacagat aactgacttt agtaccagtt ttttattatc ttttacctct
     7141 aacttagcca taagtaacct cctctgtatc taacacagcc tgtgactgaa tttgttgatt
     7201 cacttgaacg ctctgcaaac caaccattct agcatacttt ccatttttcg ccattagttc
     7261 ttcatgagta ccatattcca taatagtccc attttctaaa aagcatatct tatcacatcg
     7321 aagaattgta gacagcctgt gggctactac aattgttgtc ttatccatta ttttattaaa
     7381 gattaaatcc tgaataatct gttcactaaa tgaatctaag ttagaggttg cctcatcaaa
     7441 tatatacaaa tcagctttac tcagtagtgc tcttgcaata gccaatcgtt gtttctctcc
     7501 acccgagaaa ttttgaccgc cttcttctac aaaggagcca taacgatttt gaagacgttg
     7561 aatcgtatca tgaataccaa caatacgaca aactctcacc atatcctcat atgtaacaga
     7621 aggattacca atttttagat tatcaataat tgtccctgta aagagttcta tggtctgagg
     7681 aatgtaggaa attttcttac gtagtttacc atagtcaaga tctgataagt cattttctcc
     7741 tatacgaatt ttcccctcac tcggatttat aaatcttaat aacaaacgaa ctagcgtact
     7801 ttttcctgct ccgctttctc caacaaaagc tattttttct ccttgtttaa ttcgcaaatt
     7861 aaagtccttg ataacaggag ggcgtgaacc ataggcaaat gttacatctt taaattcaat
     7921 gtcatcacat aaggtgaagt ctctaatact ataatccaag gcaatgtctt cacgatctac
     7981 ttccatcaat tcttgaagcc gactaaccgc aacctgtacc tcttgaaagg ttaactgcaa
     8041 gccaactaaa ttctgaatag gttctgtaaa atattgactt aatgtctgaa aaaccaagag
     8101 gtccccaata gtcatttttc catcaatgat aaataaggcg cccactccca taaataataa
     8161 cccacccatg gttgaggtca ttgaagatat tgtagattga atattctgca aaacaccctc
     8221 tttataacca atttctaaag tatgaacaaa tttttcttca attttgttta aacgttgttc
     8281 ctcatcatgc tgagacttaa tggtatcaat gttacgaata gattcaatta actgtgaatt
     8341 aagaagtcca tttgcttcca tttgttcatg attaattttt ttataaggct ttttaaaaca
     8401 gtatataaga atgatgttaa caataaccat aaaaactaat atcagaaata aagattgatt
     8461 aatagtccaa aggacaaccg cactaataac tgacaaggtg atatccatga ctaatgaaat
     8521 agagactgac gtaaacacat tctttatcgt catcgcatct tgaaatcttg ttaaaacatc
     8581 accaactcta cgacttccaa aaaaactata aggaagatga ataatatggt cataatatcc
     8641 cattaaaacc ggtatatcaa tttttcgaga tagaaacaaa agaacgtgct gacgaaatgc
     8701 agatagaaga gtctgtaaga acgacactat tccaaatact atcaaaaaca tatacagact
     8761 attttttaaa gcatatggaa tcacctcgtc catgataact tttgaaaaga gactcgataa
     8821 aataccaatg atacttaaaa caaaggaagc taatatgact gtactaatca atcctttttg
     8881 attaaaaatt aaccttccaa ataaatcaag aagtcctttt ccctttagtt tccctctttc
     8941 aaaatccgaa tttggaacca taaaaagagt aataccttga taaatttctc ccagttcgtc
     9001 acttgacatc ttgcgtatgc cactagcagg gtctgctacg tagaacttac tattcctttt
     9061 gatactatgt agtaccacaa aatgattttg acctaaatca ttcttaactt gaagaatcgc
     9121 aggaaatgtt aattttggag tcaaatcttc cagtgctact cgaacagctt ttactgtaaa
     9181 attcaactta ttcagacctg aaacaatacc actgacagtc gttccataca tgtctgtacc
     9241 aataatttcc ctaatcttca tgattgatag ttcctttttg taagataaaa gaactgttga
     9301 aacaactgcc gcagcacaat ctgactggtc atgttgcatc gtacaaggat atttttttaa
     9361 catagaaata ctcaattctt tagaattaat ctaacttttc tttgatgtca cccaaacctc
     9421 aatcactgcc cagtagttct tgaattaatt tattttcaac cgtatcattc tttgttcttg
     9481 atatctttcc aagcattgta gtacagcaga tttttgccca aggactgagc ctcctttaac
     9541 aactcaaact cccttacatt atatcggcca gccccatgga aagattatag ccagactaat
     9601 caatgatata atacatacta gaatacaaaa tattttttta ttcatacttt ttctcctatc
     9661 tttattttct acctacatag tacctcttat taagctcatt ttaaaattac gttaactttt
     9721 ttcacaaatt tatttcgact ttctttttta ctttttacat tgctatgata caatattttt
     9781 aacaaaattt tattgtttgt taactttttt cacgaaaagg agaaaatcat gcgttatgat
     9841 ttcggaaagg tctataaaga aatacgtgag tcaaaggggc tgacccaaga agaggtctgt
     9901 gggggtgttc tctcaagaac cagcttatca aaaatcgaaa gtggcaagac aaccccaaaa
     9961 tatgaaaata tggaatttct tctccgtcaa atcaatatga gttttgaaga gtttgaatat
    10021 atctgtcaac tttatcaacc aagtcaacgc acagagatta tgcaaaccta tctcaatatg
    10081 cgttccatta tcgggaccag cgatcttgtc aatttatttc aaaaatgcca agactacctc
    10141 aagacccacc acgatctccc tatagaagaa atcagagata tgcttgaagt tgttatttat
    10201 ctccgtcaac acggggcagg ggaactatca aaacacgcag aacaggttgt caaaaaactt
    10261 tggaaaaaaa ttgaaaaaca agatacatgg tatgagagtg atctaaaaat cctcaatacc
    10321 attcttttca gttttcccat tgaatacctc catctcatca ctggaaaaat attgcaacgc
    10381 ctagaagtct ataaaaacta tcaacattta tatgacttgc gaatgacaat tctattaaac
    10441 ctttccacac tctatctata caatcaagat aaaaacatgt gtaagcaaat ctgctacact
    10501 ttactggagg acgccaagaa taagaaaagc tacgataggc tggctatctg ctatgtccgt
    10561 attgggattt gtagggatga tgcgaaactt atccaaaaag ggttctccct tctggagcta
    10621 accgaggaaa cttctatact gtctcatctc aaaaaagaag tagagatcta ttaccaagcg
    10681 aaggaaagat aaaaaagccg agggatttcc tcgactcttt acatattatt tgttcgttag
    10741 ttcttaatac cagccattgt taaaccagaa gtttttagct ctgccaagcc acatagtgtg
    10801 tttactacta tgtgtccatg tcaccatgaa tcgccgaacg atttaacgag aaagtatgac
    10861 ttttacgttt atcccaactc aattatgaca tttttttcaa aagtcaatat atctcacttt
    10921 ttcaacgaca agaaagaggc tgccaatcga ccaacctctt attctgaacc catcactcca
    10981 tcacttttta gcttcattcg ctttcttagc gactgcaatc tggtattcga cttggtcaaa
    11041 ccctgtgcct cccaaggaat ttcgtctttg aacagcagtt ttaggttgca agtagacata
    11101 gatatcctcg gtaatgagag aatgataggt ttgtaattcc tccaaagtcc aatcttgaag
    11161 atttttagca gacttgatag agtctagcac taatcttccc acaacctcat gagcttctct
    11221 aaatggcaag cctttccctg ccaaataatc tgccaactca gttgcatttg aaaagtcctt
    11281 ctctgttgat tcttgcattt tttccttgtt tacctgcaaa ctagataaca tacctgccaa
    11341 cacatcgagg gaatttaaaa tcgtttcgac cgtatcaaac attccttcct tatcttcttg
    11401 caaatcctta ttataagcta aaggcaagga cttcatgact gtcaacagtc caaacaaatg
    11461 cccataaact ctgccagtct ttcctcgaat caactcagcc atatctggat ttttcttttg
    11521 gggcataata gaggaacctg ttgtaaacgt atctgacaag gtaatgaatt ggtactcaaa
    11581 actacaccaa ttgatcattt cttcgcaaaa acgactcata tgcatcatga gtatgctggc
    11641 atttgataga aattctaaga taaaatcgcg gtcactaaca gcatccaaag aatttgtata
    11701 aggttgctta aactccagca aatcgctaga caattggcga tcaatgggga aagtcgttcc
    11761 tgccaaagct gccgcaccta aagggcatag gtctgtatgc ttctggttaa attcaaaacg
    11821 ttcactgtct ctttgaaaca tattgtagta agccatcagg tggtaggcaa aactaatagg
    11881 ctgggcatgt tgcagatggg tatagcccgg catgatcgtc gccacatgat tttccgccaa
    11941 gtctaataaa acacccttaa gatgagccag tttatctagg acatagccta gttgttcctt
    12001 gagatacaag tgcatatctg tcgcaacttg gtcatttcga gaacgagccg tatgtaactt
    12061 ccctgcaagg ggaccaattt tttctgtcag caacacttcc atattcatat gaatatcttc
    12121 gtttgcgata tcaaagtcaa gttgacctgc ctctagctct tctaaaagct ctttcaagcc
    12181 tacttgaatc ttttctgact cctccaaact caaaatgccc gtctgaccca acatctgaac
    12241 gtgggctaaa gaaccaatca catcaaattt agctaatttc tggtcaaaag atatactcgc
    12301 accaaagcgc tctacccagt cttcgacagt accttcaaag cgaccacccc ataattttgt
    12361 attcttagcc atatcacatc cacctctcta tccaatcgtc ctatttggcg cttttttgaa
    12421 cctcagaatg aaccttggtt ggaagtcccc ataactcaat aaagccaaca gccgcatctt
    12481 ggtcaaaggt atctgcacta gtatacgtcg ccaaattttc atcgtaaaga gaatttggtg
    12541 atttccgagc cacgacctga gcgctccccc ttatacagtt tgacttttgc agtcccattg
    12601 acaacttttt gagtctcttt aatataagca atcaaggctt gtgtagccga actaaaccac
    12661 aaagcattat aaatgagatt tgataattca ttttctatga ttggtttaaa atgagccact
    12721 tctctcacaa gcgtcaagtc ctcaatttcc ttatgagctg tcagcagggt cactgcacct
    12781 ggacactcat agatttctct tgatttaatc ccaaccaagc gattttccac gtggtcaatc
    12841 cgtccaaccc catgttttcc agctatttca ttgagttttt gaatcaaatc tgccaatttt
    12901 aacacttctc cattgaggga aactggaaca ccttcactaa actcaatctc aatgtattct
    12961 ggcatatctg gagcttgctc tggagaagtt gtgatgccaa aggcttcttc tggagcctga
    13021 ttccatggat tttccaaaat accacactca ttggcacgtc cccaaagatt ttggtcgaca
    13081 gagtagggat tgtcaaggtc agcaggaaca ggcaccccat ttttcttggc ataataaatt
    13141 tcttcctccc gagaccattt ccattcacga actggagcaa tcacttttaa attgggatcc
    13201 aaggctgcaa tcgatacttc aaaacgtact tggtcattcc ccttaccggt acaaccatga
    13261 gcaattgtag tcgctcctat ctgatgcgct atttcaacca attttttaga aatcagaggg
    13321 cggctcaagg cagataccaa gggatacttt tgttcataat aggcatgtga ctgatgagcc
    13381 actagcacat aatctgtagc aaattcgtcc ttaacatcaa tgacataaga ttctactgcc
    13441 ccaaccttaa gagccttatc atggatgaaa tctaagtctt tcccttcacc cacatccata
    13501 caaactgaaa caacatcata gtctttcttt aaccaggtaa tagcaactga tgtgtccaaa
    13561 ccgccagaat aggccaaaat tactttttct ttactcatgt tcttttcctt ctttctattt
    13621 ttcaatggat gctttaaagg catcctcaat gagtttgtct aattccccag actccttcaa
    13681 cttttgaata gttttatcga ctgcctcttt caattcctta ctatcttttt tcatggctac
    13741 cgagtaggaa tcatcttgct ctttttcaaa attgaggtct gcgattgcta aatcaggatt
    13801 attttccaca aagcccttgg caactggttc ttcaaagata acggcatcca cttgtcctga
    13861 ttttaaatct gtgattaaat tcccattttt aggcagagat acgagggaag aattttgtag
    13921 caaatctttc gccatcgtct cttgaatcga acctttctgg gctccgacct tcttctgcgc
    13981 taagtcgttg acagactgat aagtgactaa atcagatttt ttgacaatga gtttattttt
    14041 tgcagtatag tagggaatgg aaaagtcaaa caccttgctc cgttcatctg tcttagaaac
    14101 acctgatatg gcaagatcag cttttcctga ttgaacacta gccagtacat tgtcaaaact
    14161 catgggagat agttccaatt cgacacctag ttctgttgcg atagccttgg ctaattcgat
    14221 atctgaaccc acaatctgat ttttcccatc aaccactttt tggtattcaa atggagcaaa
    14281 atctggattg agggctacaa ccaattttcc tttggacttg atggcttcaa ttccagccga
    14341 ttgattgtta ctacaagcaa atagtagggg gagcatcact aaaccaaaca tcgtcatcaa
    14401 caccttcttc atcttattca taacaaagcc tcctttatgt ttattccttt tgtttgtata
    14461 aataatacac ctatcttcat cctttgtcaa gcctaaattg taattttttt caatttaaaa
    14521 cagaaaaacc taggaaaatt acataaaaat gtcattccta ggcgtattta tgctattcct
    14581 ctctggaaaa tatgagtatt cagtcagtca aaagaagctg aacgaactca ttttccctcg
    14641 cccaattcaa taatccgatg acattgttgg gctacataag catcgtgggt cacaataatg
    14701 actgttttcc cttctcgatt catctctaag agaaacttca agaccaaatc tctattttca
    14761 ggatccagcg aacctgtagg ttcatcggct aaaatcagct ggctgggttt taagatggct
    14821 ctagcaactg caattcgttg ttgttcgcca ccagacaact cggagacctt ttgatgcaaa
    14881 gtagctgaca aacctactct ctctaaaatc tcttccacct ttttgagctt atctttctta
    14941 gacaatttta catatttcag cgccagcata agattgtact cgaccgtttc atcatcaatc
    15001 agggcaaaat tttgaaacag ataagagata tgttcacgga ttattgtttg cgacttagca
    15061 gaattgaccg ctagatttgt ctgaccaaaa atctcatacc gtccgctata atcaccatct
    15121 atcaaaccca ataaatttaa caaggtcgac ttcccactac cactcttacc aacaatggca
    15181 accaaatccc cctgatcaat cctgagagac aagcgatcca aaatcacttt ccccccaatg
    15241 gttttggtaa tattttccaa ctcaatcata agatgccccc tttcaataac tctactagac
    15301 ttcttttctc catcctagaa gccaaggcta gcacaaatag tatatccaaa catgtaaagc
    15361 ctgcaaacag caggagtggc aagaacgcat gggcaaagaa aatcaagact agaagaggga
    15421 gactatagcc cagcaagagc agaacgagga gaggacggta gcgatcgacc agtttccacc
    15481 ccataaactt cttggtaata atatccctgc gcttcaataa gaaagttatt actagtaaga
    15541 agtaggaaat catcatgcta aagagaccaa acaaagcaaa aagtaggtta aaattccgaa
    15601 cagcatctcg ataagaatcc actttctctt gttgaatggc ttgaatagat gaaaatttta
    15661 aataatttcc atctgacaat ttctcaacta actctgtaat ctctttttga tgttgaaccg
    15721 tattttcaat tttaatcgga ttatttaagc cagttgttga cagggaggct ttctcatccc
    15781 acatcatatc agaatcattg accaagctaa taattggatt ggagagattt tcctttcgct
    15841 tatcactata tgggaaaaat gaccaatctc cttcataata ggcaatctcg acatccatct
    15901 cctctatcgt tcgtttttgc tgctcttcat acttcatcga atgaaaggca attaacttcc
    15961 ccaagagctg atttttatct tcttcacctt tcgtacttgc tggcatcaaa ataacttttt
    16021 taataccagt atctggtagc ttgaatccct tgctctttag aaaattgcga ttggcatagt
    16081 aaacatccac cgtatctgtt aactgatatt gctgaatctg ttctgattgg acaaaatttt
    16141 ttacaggaag actgctactc tgcacatagc ccgcctgcgt tttttctact aaatcctgat
    16201 aaaatcgata gaaataatcc aatgccttcc ctgagcctgc caactgctct tgccacaagt
    16261 tgtcattgag ttggaaagtt tctaaggtca gataatttcc ttggctgatc cactgtttct
    16321 ggtaatccaa ctctttgttt tcttgctcca aactttttcc taccccaact agcaagactg
    16381 tcagtaaaat ggtagttcca attttcatca aataattaaa gagtagacca aatttgaaag
    16441 atgaaaaacc tttcagcaga gagctgattg tcattttttg gattaagagg taagtcaacc
    16501 aactgataaa gagataaagc tgcaacagca aaaaatgaga caaccacagc ataggaaaca
    16561 aatcttttgg cttataatca agcaagaaaa acacgcctag attgatcaca agagccccac
    16621 ctaggaggag gtaaaggttg ccttttacaa catcagctaa aacagcccta tcttgaaaac
    16681 caagtaattt ttgtacccca actcgtttca tctccatcat cggttgatac actgtcacta
    16741 acacaagaag caaaatagcc aagacaaaaa caatggcaga taaaagcaaa tctcgattta
    16801 tgacttccac tgcacttttg taggtcggct ctagcaaggt agcctggtct atcttgaaaa
    16861 aatcgctcca tttctgtaca atcctatcct tgtccatctc ttgtgtagaa gttatcgtat
    16921 agcgaccatt taaactacga gatgtatcct tgatataggt ttgaaaagtc ataagctgaa
    16981 taggtttggc ttttagaaag gtcggaatcg taccaagttt attggaaatt tctttattac
    17041 tatagactcc ttcaccatct gtggtaaaat caagagaaga aatcccaaac tcttggtagg
    17101 ggaaggtatc tttatcaaaa acaccagact tgaccacctc atcgccatta tctactttga
    17161 taatagagac cttgtcttgg cttgcaacct cttcaaaaaa ctggagaatc gtttctgtcg
    17221 gtttagtgac atctttcaag tacaagtcaa atgaataagt tgtcttgccc atctcctgaa
    17281 tccgcactat ttctcgtgta acatttacat tcaggacaaa aaacgtagta cacagcaaga
    17341 gcaggagcat acaaagatga ctgatttttt tcatagagat acctcccgtg aagaaactcc
    17401 ctctccaaaa ggggagggag aattttaatt aaaatccata gaaatattcc attcccgttg
    17461 gtgggaattt gaagattgaa gcccgagccc acgcctcagc ttctgcacga tccttagaga
    17521 atttatttcc atctttaaca gttgctgtat gagagcgagt agaatgtaaa taatcagaat
    17581 aaccaaaatt tcctgaccat cctactccat agttccattg accaccatca acccatactg
    17641 ccaaaacact tgtagaagca agtatactac ataccattaa agatgcaaca ctaattttct
    17701 catgatttat ttctcctatt atcgagagct attccgtaga aacagctata gtaatttatc
    17761 aacaagtatc gtagtccatt ggactcacct tccttctatc tcatttcatt tttaaacaac
    17821 gaacttactc ttaactagga gaatagttct cttctgtatc aggtctttga acaaccagag
    17881 tagtattaat cacactctaa ctattactca agaatcagcc caataaacaa tatggatagc
    17941 gctttcaaat ttttaaactc tatcccatcc ttttatctat attatgagcg aaaatataat
    18001 aactgtcaag taatcgaagt gaattttata aaaaaaatta caagccaaat ttgcaaagtt
    18061 tacaataagc cgctagggca atcgtctatc agaatgtccg tttatttgtc aataatccga
    18121 gaaaatcttg caacgcttag aagtctataa aaactatcaa catttatatg acttgcgaat
    18181 agcaatcctg ctcaaccttt ccacactcta tctatacaat caagataaaa acatgtgtaa
    18241 gcaaatctgc tatactttac tggaggacgc caagaataag aaaagctacg ataggctggc
    18301 tatctgctat gtccgtattg ggatttgtac agacgattct aaacttatcc aaaaagggtt
    18361 ctcccttctg gagctaaccg aggaaacttc tatgctgtct catctcaaaa aagaagtaga
    18421 gatctattac caagcgaagg aaagataaaa aagccgaggg atttcctcga ctctttacat
    18481 attatttgtt cgttagttct taataccagc cgttgttaag ccagaagttt ttagcagctg
    18541 tccatgaacc gtaacgtcct gcaacgtagg catctgctac acgttcttgg ttttcagctg
    18601 agtagtcacc gttcaggtat gaatctgtta attggtaacg tccgatataa cgtccatttg
    18661 tagctgtata gctaccacct gattcttttt gagcaatcca ttctttggct tctgcttcag
    18721 atccgcttac agttgaaaca actgtttcac ttactactgg agtttctgct actggagctg
    18781 aaacagtttc atcttgagcg gctggtgccg cataagtagc tggcgctggt gttgcaacag
    18841 gcgctacagg gccatcgata accaactctt gaccaacata aatcaaatga atgttatcaa
    18901 tgtggttgtt ttctgccaat ttttcaactg ttgtgttgtg agtttcagcg atttctgaaa
    18961 gtgtatcacc ttctttaaca gtgtaagttg atgattcttg agcagataca aatgatggag
    19021 caaatactgc aaacaaggca gctactcctg caagagttgc tttaatcttt ttagttattg
    19081 atttcatatt cgaaaattct ccttctttct atagttctat catacccttt aaatattacc
    19141 gtttcttgac acttttatgt agaaatatta caaaattatt ttttatttcc ctaaataagg
    19201 tgttttttgt cataaaagat actattttta tgctatttga ggtattagaa aggttttcat
    19261 ccacaattaa agccaagccc ctcattcttt gatataatag agataagaat ttttataagg
    19321 ggaaactgat gaaatcactt cgttttcaat ctgtctttga tatcatcgga ccagttatga
    19381 ttggcccatc tagtagccat actgctggtg ctgttcgtat tgggaagatt gtctcttcca
    19441 tttttgatga tactccgaca gaagttgaat tccaactttt taactcattt gccaagacct
    19501 atcgtggtca cggaacagac ctagcccttg ttgcaggtat tttgggaatg gatacagatg
    19561 atcctgaaat tccaaatagt ctggaaattg cccacaagcg tggtatcaag attgtctgga
    19621 ccattcagaa agacagcaat gcccctcacc ctaacaccac taaaattact gttaaaaatg
    19681 cccacaagac catcagcgtg actggtattt ctatcggtgg aggaaatatt caggtaaccg
    19741 aactcaatgg ttttgccgtc tctctcaata tgaatacacc gactatcatc atcgttcatc
    19801 aagatattcc aggtatgatt gcccttgtta cagaggcgct ttcccgctat ggtatcaata
    19861 tcgcccagat gaatgtcact cgtgaaaaag ctggtgaaaa agccattatg attatcgaag
    19921 ttgacagtcg caactgtgat gaggctatcg aagaaattcg aaaaatccct catctccaca
    19981 atgtcaattt ctttaaatag gaggaagcat gttttattct atcaaagaat tggtcgagca
    20041 agcagatctg gactttcaag gaaatgtcgc agaactcatg attacaacag agtttgaatt
    20101 gaccggtcgc gaacgtgaag aagtcttcct tctcatggaa cgcaatctgg aagttatgaa
    20161 agcctctgtc caacttggcc tcaatgaaaa taaatctcgt agtggcctga caggtggaga
    20221 tgctgccaaa ttggatcact acatcgaaaa cggaaaaact ttatcagatt acacgattct
    20281 ctctgctgcc cgaaatgcta tcgcagtcaa tgaacacaat gctaaaatgg gcttggtctg
    20341 cgctactcct accgcaggaa gtgccggttg tctcccttcc gttctcactg ctgctattga
    20401 aaaattagac ctcagccacg agcaacaatt ggatttcctc tttgctgctg gtgcctttgg
    20461 actagtcatc gcaaacaatg cctccatctc aggtgctgag ggtgggtgtc aagctgaagt
    20521 tggttcagcc tctgctatga gtgctgccgc cttgactctg gctgcaggtg gaacacctta
    20581 tcaggccagt caagctattg cctttgtcat taaaaatatg ctaggcctca tctgtgaccc
    20641 tgttgcaggt ttggtcgaag ttccctgtgt caaacgtaat gccatgggag ctagctttgc
    20701 tttcatcgca gcagacatgg ccttggcagg tatagaatct aaaatccctg tggatgaagt
    20761 gatcgatgcc atgtaccaag taggagcaag catgccaact gcctttcgtg aaacagctga
    20821 aggtggactc gctaccaccc ctactggtcg tcgcctccaa aaagaaattt tcggagaata
    20881 agcttatcaa ataggagaaa ccatgacctc tatcacagcg atttttttcg atttggatgg
    20941 aaccctcgtt gatagttcta tcgggattca caatgccttt acctatacct ttaaagagct
    21001 gggggtgcct agccctgatg ccaaaactat tcgtggtttt atgggaccac ctctcgaaag
    21061 tagttttgcg acctgcctgt ccaaagacca aatttctgaa gccatgcaga tatatcgttc
    21121 ttactataag gcaaaaggca tctatgaagc tcaactcttt cctcagatta tagacttgct
    21181 tgaggagtta tcgagcagtt atccactcta catcaccacg acaaagaata catctactgc
    21241 tcaagacatg gccaaaaact tggaaatcca tcatttcttt gatggcattt atggttctag
    21301 ccctgaagca ccccataagg cagatgtcat tcaccaagcc ttacagacac atcaactagc
    21361 accagaacaa gccatcatca tcggagatac caagtttgat atgctgggag ctcgagaaac
    21421 aggtattcag aaattggccg tcacttgggg atttggagag caagcagatc tactaaacta
    21481 tcaacctgat tatatcgctc acaaaccctt agaagttttg gcgtattttc aatagcatag
    21541 actgggcgac aactctattt cagaagaaaa tgaagtaata ctcaatgaaa atcaaagagc
    21601 aaactaggaa actagctgcg ggctgctcaa aacactgttt taaggttgta gatggaactg
    21661 acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa gtcagtaaca
    21721 tatacatacg gcaaggcgac gttgacgtgg tttgaagaga ttttcgaaga gtataagtct
    21781 ctacataata aaacgcatat taccaaggtt gtgtaacttg atactatgcg tttttctttt
    21841 ttattcaatg tgggttgttt gattagcaaa ggcgataata gcttgcttca actcatctcc
    21901 actgagagtg cggaactctc caatcttttg attgatggat tctaaaggca tgacattaac
    21961 cttaccaacg aaaatcttat ccataacttg attatcaacg agttcggttg ataccaagag
    22021 ttcttcgtag agtttttcac ctgggcggat tccaacttca acgattggaa tttcactttc
    22081 agtgtggcca cttagaagca ccatcttctt ggccaagtca taaatcttga ctggtttgcc
    22141 catatcaagg ataaagactt ccccatcttt ggcataagca ccagcatgga taaccagacg
    22201 gctagcttct ggaatggtca taaagtaacg ggtcatgcgg aagtctgtca ccgttacagg
    22261 cccaccttca gcaatctgac gttcaaagac tggaatgaca ctaccacggc taccaagaac
    22321 attcccaaaa cgaactgcac agtaggttga ttggctacgt tggttaaagc cagtgacaat
    22381 caactccgcc acgcgcttgg ttgctcccat aacatttggt ggattgactg ccttatctgt
    22441 cgaaatcata accatcttag acactttagc ttcatcaaca gccttagcaa cattgtaagt
    22501 tccacggata ttgtttttga aggcttcttt tggattgcgc tccatcatag gaacatgctt
    22561 gtgggctgcc gcatgataaa caatagcagg tttgtactgc tcaaagactt gcaacaaacg
    22621 atcatagtct tgaatgtccg caatcacagg tacataatca atcccttgga acttacgaat
    22681 caattcatga taaacaaggt agattgagtt ttccccatga ccgagtaaga caatgcgttc
    22741 aggattgaag cgactaactt gacgacagat ttcagaaccg attgaacctc cagctcctgt
    22801 gactaagatg gtcttacctg tcagttctgc acccagacgc gattcgtcaa gacggatttc
    22861 ctgacgaccc aaaaggtccg taatatcaat tttttggaag ccagtacctg cttggtgaag
    22921 gccctgaaca acagtttcaa ccttaggcat cttgtaacat ttgacaccca gcttattaca
    22981 catctgcaag atacgctcat attctgacgg atccagcgac ggaatcgcaa cgatgacacg
    23041 ctcgatttga tggcgtttgg ctaattcagg cagattgtca taagagccca aaacaggaat
    23101 accaccaagt ttttgaccct ttttcttaga atccttatcc aaaataccga ccagttctaa
    23161 ttcactggtt ggatgttggt aactatccat aaagagagcc ccaccatcac cggcaccaat
    23221 caagaaggtc cgacggtgtt ctccatcacc actacctttt ttgcgtctgg agtagattaa
    23281 ctgccaagta atccgtggca ataaaatcaa gaaggtactc aacaagataa agagaatgat
    23341 gaaacggatg gagaagagtg gcaagaaggc ataacagata ctatatgaca agacactgct
    23401 agcagtcaca ccaaaaaaga ttttcatgaa atccgtaatc ttgctgtaac gactaatgct
    23461 cgcgttcaac ccccaaaaac caatcatcaa ttgatagaac aagaaggcca aactcgtata
    23521 gataatgtag tcaacaggtg ctggattaat cagcccataa aataaaatat aagatacaat
    23581 tatggaaacc accatactga aaatatcaaa tattccccag aaaacctgct tttgttgttt
    23641 atttaaaatt tccaccagat caatcacata atctgttagt tttttattca tagaaatcta
    23701 ctcctcctta aaagagtttt actatattgt tattatagca tatttttatt tatttggctt
    23761 attttatcca aataaattat tgttctcttg tactccttct tccatttaaa tcctctaatt
    23821 aaacctacaa tcgtcccaag gccataagca aagtgaatgg aaaataaaag aaagggcatc
    23881 acaattagaa atccattttt atgttttaat aaagtcagca aagtgagtaa tgacaaaagt
    23941 agaaaatagg cacctaatag taaagttatg aatacgaatg tgatcggtaa caatgctaga
    24001 ctaaacacaa gactcaaaac aaataaacaa ggaacatagt gaaataatga taaacactta
    24061 aactgaacat gacttgtcaa gccaatccac aaaccatttg aatacttttg atgcagcatt
    24121 ttcttgaatg ttggtcgaat atactgataa gatagaatac ttgggctata gcggatttta
    24181 taaccatgtt ctcgaattct ataatgaata tcattatctt cagttcggcc aagttgctca
    24241 tttactaaac caaccttctg gaaaacctct cgtttataca tcccatgaaa aatagaagaa
    24301 acatatctat cctcggaact atttcgataa ttggcaatgc tactgccaaa catattttcc
    24361 tcaacaagat gcaaggtctc tgcccatttt ccttttcctt cgacaatcgt cggtctaggc
    24421 cccccacaga caaattcacc ttgttgaata atagccacat tgttcattac aaaactctca
    24481 gtaacttttg aatgagcatc aatttttaaa ataaggtccc ctacagaatg tttaactccc
    24541 aggttaaaac cactagcttg atttttctta ggattgttat acaatctaat tgagttaaac
    24601 tctgtatctt cctttataaa ttgctgaatg atagctgtgg tcccatctgt ggacatagca
    24661 tttataaata gaatttcaac attctcttta ggataggttt gattttttaa gtcttcaatt
    24721 agaccaggca gatatttttc ttcattgtat gcactgatta caatggatac gagaagactt
    24781 tcaacatttt gagtcactac tactctcctg aatttttcct tccaccattc tatcataatt
    24841 ttcaagactt tcccattttt atcttgaaag ccagaaacct tacttgacat tatagtgaaa
    24901 aagccttaaa ataagctgtt attaaaatca gctagaagag gtattatatg aaaaagcaat
    24961 cactcttttt tgttccaggt attatcctga ttggtgtttc cttgcgaact ccttttactg
    25021 ttttacccat tattttggga aatatttcgc aaggtctgga ggtagaagtt agttcgcttg
    25081 gtgtcttgac cagcctgcct ctccttatgt ttaccctctt ttcaccattt tctacccgac
    25141 tggctcagaa aatcggcttg gagcatctct tcacctacag cctcttcttc ttgaccatcg
    25201 gctcactcat tcgactaatc aatctgcccc tgctctatct aggaaccttg atggttgggg
    25261 caagtgtcgc agtcatcaat gtcctgcttc ctagtcttat ccaagccaat caaccaaaga
    25321 aaattggttt tctgaccacc ttatatgtaa cgtctatggg gattgcaacg gctctggctt
    25381 cctatctagc tgtgcccatt acacaagcca gttcttggaa aggacttatc ctcctcctca
    25441 cgttactctg tctagcaact tttttggtct ggctcccaaa tcaccgctat aatcatagac
    25501 tagctccaca aaccaaacaa aaaagtcaaa taaaggtcat gcgtaataaa caggtttggg
    25561 caattattat cttttcaggt tttcaatcct tgatctttta caccgtcatg acctggttac
    25621 ctaccatgtc tatccatgca ggtctatcca gtcacgaagc tggcttgctg acttctatct
    25681 tatctctgat tagcattcct ttttcaatga ccatcccaag cctgacaacc agtttatcta
    25741 ctcgcaaccg tcagctcatg ctcactctgg tttcactagc tggtgtggtc ggcatttcca
    25801 tgctcttttt cccaatcaat aatttcattt actggcttac catccatctc ctcatcggaa
    25861 ccgcaaccag cgccctcttc ccttatctca tggtcaactt ttcactcaag acaagcgccc
    25921 ctgaaaagac agcccaattg tccggcctat ctcaaacagg aggctatatc ctagcagcct
    25981 ttgggccaac cctctttggt tacagttttg acctgttcca ctcttgggta ccagctgtag
    26041 ctgccctctt gctcatctat atcctgatga ctgtggccct ctttacagtg gacagagcgg
    26101 ataagatcct ttaaacttct agttttagct agaagttttt tatatataaa aattttacac
    26161 atttctcttg acagggcttt cttttagatg tacaatgtat gtgtagaaaa attatatata
    26221 aaaatcttac acattagaaa aggaggtttc ccatgtactt tccaacatcc tctgccttga
    26281 ttgaatttct catcttggct gtactggagc agggtgattc ttatggttat gagattagcc
    26341 aaaccattaa gctgatcgct aatatcaaag aatccacact ctatcccatt ctcaaaaaat
    26401 tggaaggcaa tagctttctg acaacctatt ctagagagtt ccaaggtcgc atgcgcaaat
    26461 actactcctt gacaaacggt ggtatagagc agctcttgac cctaaaagat gaatggacac
    26521 tctatacaga caccatcaat ggcatcatag aagggagtat ccgccatgac aagaactgaa
    26581 tacctgactc agctagaact ctatctcaag aaactacctg aagctgaccg tatcgaagcc
    26641 atggactatt tcagagagct ctttgacgat gctggagtcg aaggagaaga agaactcatc
    26701 gctagtttgg gaactcccaa agaagcggcc cacgaagttc tatccaatct tctcgataaa
    26761 aaaatcaatg aagcacccgc tcaaaaaaat aaccgacaaa ttttacatat cgccttgtta
    26821 gccctccttg cagcacctat cggcattcct ctgggaatcg ccatcctcgt gaccctgttc
    26881 gcaatccttg tagccgcttt gactgtcatt ctggctttct ttgcagtttc catactgggt
    26941 atcatcggcg gattcctatt tttagttgaa agtttcactg tcctcgccca agccaaatca
    27001 gcctttatct tgatttttgg ttctggttta ctggctatcg gtgcttcttc gctagtttta
    27061 cttggcattt cctatgtaac tcgcttcttc ggtctactca ttgttcgtct ggtacaattt
    27121 gttcttaaaa aaggaaagag aggtaaccag catgcgtaaa tggacaaaag gatttctcat
    27181 ctttggtgtg gtgactaccg ttatcggctt tatcctgctt tttgtaggta tccaatctga
    27241 cgggattaag agcctacttt ccatgtccaa agaacctgtc tatgatagcc gtacggaaaa
    27301 gctaaccttt ggcaaggaag tcgaaaacct agaaattact ctccaccaac acacgctcac
    27361 catcacagac tctttcgatg atcaaatcca catttcttac catccatctc tttctgctca
    27421 ccatgatctt atcaccaatc agaacgatag aactctgagt ctcactgata agaaactgtc
    27481 tgaaactccg tttctctctt ctggaattgg tgggattctt catatcgcaa gtagctactc
    27541 tagtcgtttt gaagaagtta ttctccgact accaaaaggg agaactctaa aagggatcaa
    27601 catctcagcc aatcgcggac aaaccaccat cataaatgct agccttgaaa atgcgaccct
    27661 caatacaaac agctatatcc tccgaattga aggaagtcgt atcaaaaaca gtaaactcac
    27721 aacacccaat atcgttaata tctttgatac agttcttaca gatagtcagc tagagtcaac
    27781 agagaatcac ttccacgctg aaaatatcca agtccatggt aaggttgaac tgactgccaa
    27841 agattatctc agaatcatcc tagaccagaa agaaagccaa cgaattaact gggacatctc
    27901 aagcaactat ggttctatct tccaattcac aagagaaaag cctgaatcaa gaggtacgga
    27961 attaagcaac ccttacaaaa ctgaaaaaac cgatgtcaag gatcaactca ttgcgagatc
    28021 tgatgataat attgatctaa tatccacacc aagcagacgt tgacaaaaac gcttacatct
    28081 gctactatgg aagcatattt atctaactaa aaaggaggtt ctaccatgaa acaagaatgg
    28141 tttgaaagta ataattttgt aaaaacaaca agcaagaaca agcctgaaga gcaagctcaa
    28201 gaggttgcag acaaggctga agaaacgata gccgatttcg atacaccaat tgaaaaaaat
    28261 actcagttag aggaggaagt ctctcaagct gaagtcgaac tggaaagcca gcaagaagag
    28321 aaaattgaaa ctcctgaagg cggtgaagcg agaacagaaa tagaagaaaa gaaggcatct
    28381 aattctactg aagaagagcc agacctttct aaagaaacag aaaaagtcac tatagctgaa
    28441 gagagccaag aagctcttcc tcagcaaaaa gcaaccacga aagagccact tcttatcagt
    28501 aaatctttag aaagtcctta tatccccgac caagctccaa aatctaggga taaatggaaa
    28561 gagcaagtgc ttgatttttg gtcttggcta gtggaagcga tcaaatctcc tacaagtaag
    28621 ttggaaacaa gtatcacaca cagttacaca gcctttctct tgctcattct gttttctgca
    28681 tcttcctttt tctttagtat ctatcacatc aaacatgctt actatggaca tatagcaagc
    28741 attaacagtc gcttccctga gcagctagct cctttaactc ttttttctat catctctatc
    28801 ctagtagcga caacactctt cttcttttca ttcctcttgg gtagtttcgt tgtgagacga
    28861 tttatccacc aggaaaagga ctggacgcta gacaaggttc tccaacaata tagtcaactc
    28921 ttggcaattc caatcttcct cactgctatt gctagtttct ttgctttctt tgatagccta
    28981 cgatttacag ctctcttgtg tgtgattagc attggaatca ttctgcttgc cagtctccat
    29041 atcattacaa gaccaagtca agcaagtgaa accgactcct tctatcaatt attcttgtct
    29101 gtccttgtga acggagttat tatcctcctc ttctttgtag ctgaagtggc actgattgga
    29161 gattatcttc gtatcttggc ctttctttaa aattcaatcc tgtcatcctt ggcaggattt
    29221 tttctatgtc aaaaaagcaa gtcgattgac ctgcttctgc tttacttttc ttgtgctaat
    29281 gttttaaaat cttgtactag gatgggttgt atttctattt gattggcgtc tagttggtgg
    29341 taaaaagatg ggggtaatac ctctaagaat tttgcatagt ccaagcgagc tatggattca
    29401 tagtcttctg gtttagagtc gtctcctgtg atttgaacca agtcaatctc ccactggact
    29461 tccttatcca ccaattgctc aatataggct gcaggaacaa acggttctct cggtaaaact
    29521 gtcttgactc cttgagctag atggtaaacg ccatgcactt ttccttctcc atcctgatag
    29581 aaggaaactc tcgcaaagta ggcatctgtc tcttgaaccg cacgcacacg cgcttcaaac
    29641 tgagccaagc catctgcctc taaaaagctt ttcaagttct cacgactaaa gaaaatagga
    29701 ttaaaaattc cttggcaaat cgtaaaacga gctacagggt ctgctagata ggcttgaata
    29761 cttgcttgga aataagcttc aaaatcaaaa ccatctagcc cttcaatatc agtccctgta
    29821 taagcaagca aagcatctaa aaatgacttg ataatctgcc agtctgtctt tgttagtagg
    29881 tcaggaagat cgacacggta agccttttga ccatcagcat aactgacctt aaaaagaaat
    29941 tgtgattgcc ccactatcgc acactcaata tactcgagac gattaagagg ctgacggaga
    30001 tagactacat catagctatg tgactccaaa ccgtctagca aggccaagat cgacttggca
    30061 ttcaaaatct cttgttctcc taaaatgctc tgtttatttg gaataaaaaa tgttttcgcc
    30121 ataactggac tcctttgaaa tcgtttacat acagtatacc ttatttttct gaaagataca
    30181 aaaacaaact ttagattttt gagtacaaag catagaaaaa cagcccctga ggactgtttg
    30241 atcttataca gtagctgcct gatccaagct ttcaccgata gcggctaggc gctcaatcac
    30301 ttcagcttgt gtcaattcat tttttgaaac atagcggtta cgtgggtgaa cacggcactc
    30361 gtgtgagcat ccacgaaggt acttgtcttc attttcttct gatgtcaaga tacgacggtt
    30421 acagaaggga tttccacagt tgacataacg ttcacatggt gttccatcaa accagtcttt
    30481 ccctacgatg gttgggttga catggttgac atcaacggcg atacgctcgt caaatacgta
    30541 catttttcca tcccaaagct caccttgaac ttctgggtct ttaccgtaag ttgcgattcc
    30601 tccgtgcaat tggccgacat ctttgtagcc ttcacggacc atccagcctg agaatttctc
    30661 acagcgaacg ccacctgtac agtaaaccac gacacgcttg tccatgaatt tttccttgtt
    30721 atcacggacc cattgtggta actcacggaa gttgcgaata tctgggcgaa tagctccacg
    30781 gaaatgtcct aggtcgtact cataatcgtt acgtgtgtca aggacaacgg tatctttatc
    30841 aagaagcgct tctttgaact cttttggaga caagtaagca cctgttgttt caagtgggtt
    30901 gatgtcattg tcaaagtcgt tgtcttccaa accaaggtgg acaatttctt tcttgtagcg
    30961 aacaaacatc ttcttgaagg cttgttcatt ttcttcgtca atcttgaacc agagttcttc
    31021 cattcctgga aggctgtgaa cgtagtccat gtatttttga gttgtttcat agtcacctga
    31081 aactgttccg ttaattccct cgtcagcgac taggatacgg cctttaaggc cgattgattt
    31141 acagaaagcc aagtggtctg cagcaaattg ctctgcattt tcaattggag tataaaggta
    31201 gtaaagtaag acacgaatat cttttgccat aagatttgtt ctcttttcta ttcttaaatt
    31261 ttctaaattt tttatttatc tacactagta tacctgcttg agaaaacgaa tgcaatttat
    31321 ttgactggaa attgtagagg gttctcgaaa tttcctgaat ggttaaaata aggacaagag
    31381 aaaacatgga tatctatatc cttgtgccaa aaaaaccact gccctcccca gaccaacctg
    31441 aggaaagcag tgattcttat tttaggagtt aggaatgaat acacgaaatc aatttagctg
    31501 attatttttt gtttttcaag aattcatcgt attgtttttg catttcgttc aatacttttt
    31561 cgtaggcacc ttcagatttc aatttttcca tcaattctgg aatcgcttta tctgggtcta
    31621 cagtaccagt gttgatagct gtatcaaatt gttgcattgt gttagcaata gctgagattt
    31681 cagatttcac attgtcagta ttgaagataa atccaagcgc tggagattct ttagcttctg
    31741 ccaattcttt cttagaattt tcgatttgtt ggtctgtaac gttttcgttg atgtaaagga
    31801 tccagttgtt accagtgttc catccaccca tgtgagtgtt tcctttgtag ccatcaagaa
    31861 cgcgaacacg gttttcttta ccttcaattt tttcccagtt cttgccttct ggaccgtaaa
    31921 caagaccgtt caagagttct ggattcgtat tcaagaggtt caagatttcc attgattttt
    31981 ctttgttctt agagttgttt gagatgacaa agttagcaac ttgtgttgtt tggtttttct
    32041 tgatgaagtt agtaattggt ttgatttgga tatctttgtt ggcaacacgt gaaagcaagc
    32101 tgttaccgta gtcagctggt cctactgttt cttcacgaac gaaccaagta tcttgttgaa
    32161 ggtcaaagga agtatcgctt gttgcgacat cttttggaat gtagccagct tcatagaatt
    32221 tgtgaagagt cttcaagtgt tctttgaaac gaggcacttc gtaacggttt acaactttag
    32281 tagtatcgcc ttcaaggtca ataacgaatg gaagcccgtt tgctactggg tagtcaaagt
    32341 tatcagatgg gatgaaaact ttaccaatag caaatggtac tacgtctgga gctttttctt
    32401 taatttgttt caagactggc tcaagagttt cgtaagaagt aacacctgaa atatcgatac
    32461 catatttggc aaggagagtt ccgttgaagg caaagttttg agatgatgca acgttggctg
    32521 caactggaac agcgtaaatt ttaccgttta cagtattacc cttgatgtaa gctgggtcaa
    32581 gtgccttgta aaggtcttta ccttcttttt tgtacaattc tgtcaagtca gcataagcac
    32641 ctttttgagc atttacaata tagttatctg caaaggcgat atcatagttt tcaccagatg
    32701 atgtgataac tgacattttc ttaccatagt caccccagcc aaggtattgg atatccaatt
    32761 tagcaccaac tttttcttcg atgattttgt tggcatttgc taacaattca tccaagttat
    32821 ctggtttgtc accgatttgg tacattttga taacaggttt gtcacctgaa tcagcagctt
    32881 ttttgctgtt acctgtcaag ttgccacaag cagcaagacc tgcagccaga gcgactacac
    32941 tagcagatgc aaaagcatat tttttccagt ttttcatgat aaaaactcct ttttttattt
    33001 ttaaacttat aaacaatgta atgatcttat actcaatgaa aatcaaagag caaactagaa
    33061 aactagccgc aggctgctca aagcactgtt ttgaggttgt agataagact gacgaagtca
    33121 gttacatata tctacggcaa ggcgacgttg acgcggtttg aatttgattt tcgaagagta
    33181 ttaacttcac acaagggaag ttgggaactg agaaatgttc tttttcaata agcactattc
    33241 tttcacacca ccgatagtca aaccttttac aaagtagcgt tggaagaatg gatataaaat
    33301 cgcgattgga agggttgcaa ccacaaccat ggccatacga cctgtttctt tcggtagagc
    33361 aactcccagt tgaccagtca agccgaccgc tttggcaatg tagtccatat tttgttggat
    33421 ttgcatgagc aaatattgca atggatacaa gttatcactc ttgatgtaaa gaagggcgtt
    33481 gaaccagtca ttccagaaac caagagctgt caaaagcgtg atggttgcga tacctggtag
    33541 tgacaatggc aaacagattt ggaagaaaat ccgggcctca ctggcaccat cgatacgagc
    33601 cgattcgaga atggcttctg gaatggtctt cttgaagaag gaacgcatca agatgatatt
    33661 gaatggtgag agaagcattg gaacaatcaa ggcccaaaca gtgtccccaa gctgaagtac
    33721 acgggtcacc atgatataac ctggtaccaa accagcgttg aacaacatac tgagaaggac
    33781 gaagatggta aaaaatctgc gatacttaaa ggttgtccgt gaaatagcgt aggcataggt
    33841 tgttgtgata aagacatttg tcaatgtccc aactacggtt acaaagacag agatgaagag
    33901 ggcttgtagg attttatcct taaactgtgc caaaaactca aaaccgtcta agccaaattg
    33961 ggatgggaag aagctatagc cgtattggag gaggcttttc tcgtctgtca ctgaaataat
    34021 gataacgaat acaaaaggta ggatacaaga gagggcaatc aaacccgaaa tgatactgaa
    34081 gaagatatct gctttcttac tgaaggagtg aatgccgaca ttatcaattt tttctttttt
    34141 aattttcttt tttgccatat tctcctcctt tctagaacaa agctgagttt ggatcgactc
    34201 gtcttgcaag caagtttgat aggataacca gaatcaaacc aacaacggat tggtaaagac
    34261 cggctgctgc agccataccg atatctgctg tctgagtcaa accattaaag acatatacgt
    34321 ccaaaacgtt ggttacattg taaagctgac cagcattgtg tgggatttga tagaagagac
    34381 cgaagtctgc gcggaagata tttccgactg caaggatggt caatacagtt acaagcggag
    34441 tcaactgagg aatggttacg ttgcgaatac gttgccactt gctagctccg tccactgtcg
    34501 ctgcttcgta gtaggttgga tcaattccca tgatcgtcgc atagtacatg acactgctat
    34561 atccaaatcc tttccaaata cctaggaaaa gtaggagata gggccagatg cccaggtcag
    34621 cgtagaaatt gacttctttg agaccaagac tttccaatag atgattgaac acccctttat
    34681 caatatttag gaaggcatct gtaaagaaac tgatgataac ccaagacaag aagtaaggga
    34741 acaacataga agtttgaaaa atcttcacca ttctcttaga acggagctcg ctgaggataa
    34801 tggcgatccc tacagataca actaaaccta gaaagataaa gccaagattg tagaggacag
    34861 tatttcgtgt gataataaag gcgtctcttg aactaaataa gaatctaaaa ttatcgagtc
    34921 cgacccattt actatttatg atactatcta tgaaaccatt actggtcatg tggtagtctt
    34981 tgaaggcaac cacgttccca aatactggaa tgtaaaagaa tagaatcaac cagagtgccc
    35041 ctggcaaaac catcaagaga aagatccagt tgtctctcaa tgtttttgaa aactttttca
    35101 taatttcctc cctttttatt ttgatatcca tctaaaaatt cttttttaga cttttgataa
    35161 cgattacatt attagtatac tcctatttgc aggttaggtt aaactcctaa ttatagaaaa
    35221 aactccacaa attatgtagc agatttaaaa ctttatcacc actatcaaac aaatgtccta
    35281 aatcaattgt ttattttatc tctattagcc cagtgatggc gtcactctgt tataagcatc
    35341 caacaacggg gtatactgaa aaatctccag actagggaac tcagcgatag ttcctaatct
    35401 ggagattttt aatatgttat taggcgtttg ctttcaactt agcaataacc tctttaagat
    35461 tatcaatcaa ctctgctgca gtatgctcag agcctttttc atctgccaag aacaaaactg
    35521 ctttttgaag ttctttttga gagttttcaa ggacatcctt atctactgtt tcaaggtttg
    35581 agtctttaag aagtttactt aattccttgg ctaatttctt gagtttgatt tgcagactca
    35641 tcttctcctg ctgtttcttt gcccgctgtt tgtcctccat ccttagttgc tgactggctt
    35701 tccttaatgg actctaggga agcaatggca tctttgactg tttgcaagat atcacgtaaa
    35761 ccttgctctg tcaaactatc atctgtaaga gctttcttag cctctgccaa aaccagacgt
    35821 gctgaatctg tggtaggatt cgatacacct gtcaatgatc tcaaaagatt ttctaaggtt
    35881 tgagtctgct tactaatact agactaaaat caaaaagcat tacataacag tgatatgaaa
    35941 tcaactaaag aagaaatcca aaccatcaaa acacttttaa aagactctcg tacagctaaa
    36001 tatcataaac gccttcaaat cgttctatag taaaatgaaa caagaacagg acaaatcgat
    36061 caggacagtc aaatcgattt ctaacaatgt tttagaagta gatgtgtact gttctagttt
    36121 caatccatta tatttcgtct gatgggcaaa tcttataaag agattataga acttttatag
    36181 tagtttgaaa taagatgtga acaactctat caggaaagtc aaattaattt atagaaatat
    36241 tttagcagcc aaggtgtact gttatagatt caatacacta tacttggtgg tttagctctc
    36301 ctgttttctc ttttagcttt aaccagccat aaatggtatt acgtgagatt tggaaaacgt
    36361 gtgatgcttc tgttatacta cctgttcgct cacaataaga gagaactttt ttacgaaaat
    36421 ctattgaata tgccataaaa agattatacc acattgtgta ctatttttgg ttcactttac
    36481 tatatcactt tggactatat cggtctagtt atgtctaaac gattatagct ggatactaag
    36541 agaaatcaaa aaagcactaa gggagaacgt cccaaagtgc ttaatatcaa ggcctcaaag
    36601 cctatcttat ttaataaaat attacaacat tttgttgtag aattcaacga caagtgcttc
    36661 gttgatttct gggttgattt cgtcgcgttc tggcaagcga gtcaatgaac cttccaactt
    36721 ttcagcgtcg aatgatacga atgctggacg tccaagagta gcttctactg cttcaaggat
    36781 tgctggaact ttcaatgatt tttcacgaac tgagatcact tgacctggag ttacgcggta
    36841 tgatgggata tcaacgcgtt tcccgtcaac aaggatgtga ccgtggttta cgaattgacg
    36901 agcttgacga cgagtagtcg cgagaccaag acggtaaaca acattatcca aacgacgttc
    36961 caaaagaagc ataaagttga aacctaggat tccacctttg atttttgtag cttgtacgaa
    37021 caagttacgg aattgttttt cacctacacc gtaagtgaaa cgaagttttt gtttttcagc
    37081 caattgcaaa ccatattctg acaatttaga acggttgttt ggtccgtgtt gtcctggtac
    37141 atagttacga cgtgccaatt ctttacctgt acctgtaagt gaaaggccaa ggcgacgagc
    37201 ttgtttccaa gatggtcctg tataacgtga catatgaatg tcctcctgat ataaataata
    37261 tttcggtgga aatagtcact tagaaagccc tgattcgtgc agatgccctt cgcctaaaca
    37321 gccaaggtta cttgtcataa gacacctgtt gacgagcttc atgctttcct gctgatattt
    37381 cacactaaat tcattttacc atgaatagct ggatttgtaa aggggtttta ggctttattt
    37441 tcactaccag agaggttgag aacgagggta aaggtacttc ctagaccgta ctggctgctg
    37501 actgtgattt ccccacccaa ttgatgggcc aattcacgcg caatcgcaag tcctaatcca
    37561 tgaccacctg tcttcatgtt acgcgaagtt tcgacacgat aaaggcgttt gaaaatattt
    37621 tccaaatcct ctggggcaat accctgccct tcatcggtca cactgattga aagctggtcc
    37681 ttctccagct tagccaccac ttccagcttg gttcctggag cagaatattt aaaagcgtta
    37741 tcgaccagat tcaccaagat acgagaaagc ttagcataat ctccctcaat ccgggcagac
    37801 tctgggatta cctgcaagtg gacatctctt ctctcctgct caatcaaaaa ctgaaattca
    37861 ctcatgcact caattaagag cttgtccaga aaaatactgt ctttactggt agtttccacc
    37921 tgatttctag ctgtgtttag ggtcaaaaaa ttcaactcct caaccagttt attgagcctc
    37981 tccgtctggc gtccaatggt tgctagataa tgagcttgct ccgactcctt gataatacca
    38041 tccaaaatcc cttctaccgt cgcttggatc gaagtgatag gagtcttaat atcatgcgac
    38101 aactgggcaa tcatcaagcc cttttctcgt tcgctttctt ccaaggaatc aaagcttacc
    38161 tgcaaatcat gggacatctc attaaaagtt tgccctaatt gctgaaattc tacaggacct
    38221 tgaacctcca aatttgaagg aaaatccttg gccgctaccc gcttggcatg ctccttgagt
    38281 ttgcccaacg acgtaaagac tggcaatagg agaaagagac taatcccagc accgacaagg
    38341 ctggcaacga tggtcatccc aagcaaaaag taaatctcgc ctttcgcaat cagcattttt
    38401 tgaacagccc aaaaaacaac caaaatggtt aagagggttg aaataatata tccaaccaaa
    38461 atataacttt ttagtttcat gtttgtcctc tcggtttctc tatcttatat cccaaccccc
    38521 aaactgtctt aatagtgggc gtttggtcac tactatattt tgccagctcc tgtcgaagag
    38581 catggatatg cacattcaag gtattggtgt catccacgta gtcttctttc cagatctttt
    38641 catagaggtc tgtcttggag aaaactcgct ctggattgct agctaaaatc cacagcaatt
    38701 caaatgattt aacagttaaa tccagcattt cttctcctat ttgaacttca tgactactat
    38761 gattcatttt tagattgcca agggaaatca gctctgtttc gcacccacga tgaaggcggc
    38821 gcaaaatatt gtggacacgc aaaactagct cacgtgggct aaaaggctta gcaataaaat
    38881 catctgctcc caagctcagg ccgtaaatct tgtcctgttc actggtctta gcagtaataa
    38941 ataggaaagg ctgctctggt gataagtatt gaacctcact gattaaatca taaccatcca
    39001 tccgaggcat catgacatct gtgataatca aatcaatcgg ttttttcttg aacagctcta
    39061 gcgcttccag tccatcatgg gctaccaaga cctgataacc tgcctgaatt aagtatctct
    39121 gatgaatatc tgtgatttct acctcgtcgt caacgagtaa aattgtcttt cccatctgtc
    39181 tctcctttga taaaaacagt gctatactgc tttaagtata acactatttt tattgtttta
    39241 cgatgatttt aatctgctat tgaaagaaag tcctgattgc tgattgagtt gttaaactaa
    39301 tcttagtcag cccactatcc atcatttatt tccttagctg attagttttc ttcttttttg
    39361 tttttcaaac ctagaccacc gagtaaacct gcaagcgcaa gcccaaggaa accaatactt
    39421 gccattgatg tttgagtctc accagtattt ggtagcatag ctttatcctc tgacatcatc
    39481 gtatcagaca tcttgttagc agaagcagcc atgttttcac ctgccatcgt gttggtagaa
    39541 cttgtcatgg tgtcagcagg catgctatct gtagtacctg tagcatgatt gtgattcatc
    39601 ggagtcacgc cagaaccaga gttagaaggt gataatgaac catttgctgt gtctgatgtt
    39661 tctttaacat ttat
//
LOCUS       DBEJJV010000016        39552 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.016, whole genome shotgun sequence.
ACCESSION   DBEJJV010000016 DBEJJV010000000
VERSION     DBEJJV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.016"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..237)
                     /locus_tag="ACL3GT_000954"
     CDS             complement(<1..237)
                     /locus_tag="ACL3GT_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516633.1"
                     /translation="MKILNIELANVEQTDLGFEHWVDVTYQVPILKNEYTVKLLLLME
                     CRIEDQEVIEYLVSTWKYRDLVLHSVKMYEIEKSE"
     gene            complement(469..1425)
                     /gene="lytA"
                     /locus_tag="ACL3GT_000955"
     CDS             complement(469..1425)
                     /gene="lytA"
                     /locus_tag="ACL3GT_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HGR0516634.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYIKPDGTMADKPEFTVEPDGLITVK"
     gene            complement(1425..1760)
                     /locus_tag="ACL3GT_000956"
     CDS             complement(1425..1760)
                     /locus_tag="ACL3GT_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140911 - pore-forming activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HGR0516635.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            complement(1764..2180)
                     /locus_tag="ACL3GT_000957"
     CDS             complement(1764..2180)
                     /locus_tag="ACL3GT_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HGR0516636.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFAFLYSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            complement(2190..2540)
                     /locus_tag="ACL3GT_000958"
     CDS             complement(2190..2540)
                     /locus_tag="ACL3GT_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516637.1"
                     /translation="MAETIQNTDNLLDLTKITEPFDLASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTDPTVKPKE"
     gene            complement(2543..2746)
                     /locus_tag="ACL3GT_000959"
     CDS             complement(2543..2746)
                     /locus_tag="ACL3GT_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516638.1"
                     /translation="MNTEQLNQALRMTISEISTTSTNSMITSNILSIQLDEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            complement(2727..2843)
                     /locus_tag="ACL3GT_000960"
     CDS             complement(2727..2843)
                     /locus_tag="ACL3GT_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="HGR0516639.1"
                     /translation="MNNNMLTNIALKAIQEFALENRKRTHRLENLENEHRTA"
     gene            complement(2840..9283)
                     /locus_tag="ACL3GT_000961"
     CDS             complement(2840..9283)
                     /locus_tag="ACL3GT_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HGR0516640.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQISGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGIEAKIQAQIEATDKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKETKSKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQVEAEIAKQVEALVQTKKELAGASTLLAQE
                     AKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKRTIANDIRPKQAQAEAEIAKQVEV
                     LSRTKNELSGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQV
                     GGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTIDVSDSPATGFDKAIRLTSSNARD
                     QIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNSGISPIFTLKDENWTKL
                     SFTSARNRAGVASIGYVYLVNAEVGEYLDVLAPQLEDGSLATSSKEAPEDIEGQISTV
                     ESTFKQRADSLAAGVNRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLS
                     QAEFEVRAGSIRQEILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQD
                     IPKTGIWTTSTYTATIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIP
                     GSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNES
                     KQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANSL
                     DAGVSRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSI
                     RQEILNATKDKADKTLVVSEAGKLREEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVT
                     GQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHYL
                     FRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGATS
                     GTAWVTGIKVEIGSVATDWSPAPEDADGLITEAKATFERTAQGLRTDLSAIQEYVNKD
                     GQRQEALQRYTREESARQATAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKDI
                     ASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRI
                     NSNKQGADNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLVRKV
                     ETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNS
                     DFKNGTNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYV
                     LNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEM
                     DNAYIRFDNNGSSSGTADLYITEVDLYKGYKSRTWQPHPEDAVADANKKLEATQTKMT
                     QLAGSWVVENINSAGDIISGINLGANGHNRLVGKLTHITGETLIDRAVIKSAMVDKLK
                     TANFEAGSVTTTILEAEAVTAEKLKVDDALIRKLTAKDAFIDRLTSKRIFSIKVESVI
                     SSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANWGNN
                     WNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIELG
                     SKDVLGDGWNPKGGRNAVVWWNQVGSGSLKYWMEQKSDRRLKENITDTAVKALDKINR
                     LRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIKAI
                     QELNQKIEKMEKTIA"
     gene            complement(9288..9638)
                     /locus_tag="ACL3GT_000962"
     CDS             complement(9288..9638)
                     /locus_tag="ACL3GT_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6711 family protein"
                     /protein_id="HGR0516641.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            complement(9647..13300)
                     /locus_tag="ACL3GT_000963"
     CDS             complement(9647..13300)
                     /locus_tag="ACL3GT_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516642.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSIATIGLGIGVFLAESIANG
                     LGRQKERITRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFAETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDMFQKAWTGLTNIFSKLGSWFGERWNDVTSALSKVASWFGD
                     IFGKAFDAVKNAFSSIGDFFKGVWDTVKSIFVNAGQMVGEAVGGAFKSAVNAVLGTIE
                     NVVNGFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGVSPQGGFSGDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
     gene            complement(13287..13637)
                     /locus_tag="ACL3GT_000964"
     CDS             complement(13287..13637)
                     /locus_tag="ACL3GT_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516643.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYI
                     LSRMITNHVSLLLSNDAKIVELWEYAPELFVEEQQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEVNGNS"
     gene            complement(13676..14056)
                     /locus_tag="ACL3GT_000965"
     CDS             complement(13676..14056)
                     /locus_tag="ACL3GT_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6096 family protein"
                     /protein_id="HGR0516644.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVVE"
     gene            complement(14061..14474)
                     /locus_tag="ACL3GT_000966"
     CDS             complement(14061..14474)
                     /locus_tag="ACL3GT_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HGR0516645.1"
                     /translation="MLANGIKLAFSETKGNYQNLVGLKEVPEFGIEPEKVENTTLADT
                     VKKYEFGIGDAGELEYKFAYNNSSATAPYRVLRKAADGKKKLYFEQTYPDGTKVTFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELTFVDGIGG"
     gene            complement(14477..14845)
                     /locus_tag="ACL3GT_000967"
     CDS             complement(14477..14845)
                     /locus_tag="ACL3GT_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516646.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            complement(14842..15357)
                     /locus_tag="ACL3GT_000968"
     CDS             complement(14842..15357)
                     /locus_tag="ACL3GT_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HGR0516647.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQANHSGISPEV
                     SVTYKSNPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            complement(15332..15670)
                     /locus_tag="ACL3GT_000969"
     CDS             complement(15332..15670)
                     /locus_tag="ACL3GT_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516648.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            complement(15651..15962)
                     /locus_tag="ACL3GT_000970"
     CDS             complement(15651..15962)
                     /locus_tag="ACL3GT_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HGR0516649.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIEVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            complement(15964..16152)
                     /locus_tag="ACL3GT_000971"
     CDS             complement(15964..16152)
                     /locus_tag="ACL3GT_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516650.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVA
                     ISDVLEKILPEPEFLEED"
     gene            complement(16162..17187)
                     /locus_tag="ACL3GT_000972"
     CDS             complement(16162..17187)
                     /locus_tag="ACL3GT_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HGR0516651.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFGAALGNVSDNVAMGKTAGANNAYNAVLDVSEKLDEL
                     GITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKPSTQGKVVNRAKAWKTGTTYKEGDTVTHADKVYVAVKDISNSSTAPDTDTTNW
                     KEKTGKK"
     gene            complement(17210..17725)
                     /locus_tag="ACL3GT_000973"
     CDS             complement(17210..17725)
                     /locus_tag="ACL3GT_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HGR0516652.1"
                     /translation="MNEETQTVEVETVEEQKVPAEPAPQPQDEKKYTDADVDAIIDKK
                     FAKWKSEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAKAML
                     SERDLPVELVNVVDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQTVQQ
                     EVTEKWRKDFL"
     gene            complement(17893..18144)
                     /locus_tag="ACL3GT_000974"
     CDS             complement(17893..18144)
                     /locus_tag="ACL3GT_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6275 family protein"
                     /protein_id="HGR0516653.1"
                     /translation="MLEKAKQLASQEFSRLSGREIKAEDCFVVWFSKTLQNWKALVST
                     NKITSSETCGDYAEITHNGDKKETYVDVYAKVSNRAIKD"
     gene            complement(18146..18391)
                     /locus_tag="ACL3GT_000975"
     CDS             complement(18146..18391)
                     /locus_tag="ACL3GT_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516654.1"
                     /translation="MKYRKKPVVVEAVQWNGNNHKEVINFAENKIWFDALGNIWIATL
                     EGDMVAKKGDYIIKGVQGEYYPCKPDIFAETYEKTEE"
     gene            complement(18443..18670)
                     /locus_tag="ACL3GT_000976"
     CDS             complement(18443..18670)
                     /locus_tag="ACL3GT_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HGR0516655.1"
                     /translation="MAILDDLQALYDNGWDASFNYNGQVCGIFPNSIYDIVVIIADNE
                     YRASSFDDLISLQIEGKTLPEIMNEVEVQYG"
     gene            complement(18658..20061)
                     /locus_tag="ACL3GT_000977"
     CDS             complement(18658..20061)
                     /locus_tag="ACL3GT_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HGR0516656.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQIGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTNIWKNTGKLTSSIKDELLISLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLNYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKTELVPADM
                     TYKEWYSKYVDGNRESIKRKAFDKTIKDGIIVSVSGTTIGHTPPGKIGLPNSVVQHNA
                     TNGDVLGRTYYDARGFKTKDVHFTNHKQPARHPYGKIGEHAHDFVFDDEGKFVSRSTR
                     ELTDDERKENQDILWRY"
     gene            complement(19970..21439)
                     /locus_tag="ACL3GT_000978"
     CDS             complement(19970..21439)
                     /locus_tag="ACL3GT_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0046798 - viral portal complex [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0051027 - DNA transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HGR0516657.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHNTESSRLKNLKSYYM
                     GDHAILNHKRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADSDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKYQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNQD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRSVR"
     gene            complement(21451..22749)
                     /locus_tag="ACL3GT_000979"
     CDS             complement(21451..22749)
                     /locus_tag="ACL3GT_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HGR0516658.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVVRLLKYSWGNLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            complement(22727..23227)
                     /locus_tag="ACL3GT_000980"
     CDS             complement(22727..23227)
                     /locus_tag="ACL3GT_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HGR0516659.1"
                     /translation="MQEGRTSCGFFDCLKGGDGKLSGLRIKQKRFADEYIISGNATEA
                     YKKAGYRVSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMR
                     GETQEQTLISIGELGQTITDIDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFAN
                     ESDIPD"
     gene            complement(23472..23554)
                     /locus_tag="ACL3GT_000981"
     tRNA            complement(23472..23554)
                     /locus_tag="ACL3GT_000981"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23521..23523),aa:Tyr,seq:gta)
     gene            complement(23635..24039)
                     /locus_tag="ACL3GT_000982"
     CDS             complement(23635..24039)
                     /locus_tag="ACL3GT_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HGR0516660.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            complement(24112..24483)
                     /locus_tag="ACL3GT_000983"
     CDS             complement(24112..24483)
                     /locus_tag="ACL3GT_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516661.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            complement(24480..24917)
                     /locus_tag="ACL3GT_000984"
     CDS             complement(24480..24917)
                     /locus_tag="ACL3GT_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HGR0516662.1"
                     /translation="MTPRYRAWIKTEKRMFFSDDILAIDYENKEIVTQQVYFESGLAV
                     ERDIYCYDFDDIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            complement(24929..25351)
                     /locus_tag="ACL3GT_000985"
     CDS             complement(24929..25351)
                     /locus_tag="ACL3GT_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516663.1"
                     /translation="MTETIKLPDYYEPDWENARYGSLEELKELLLFKRIVKWDKDFLL
                     LEDGTKVTIEMSESDCCASAGGEFQDVSLDAVITNIEIGEPEEIPDHWGTGYKNKVTI
                     FHNQNPVAIANCEAEHNGYYYSVCSLVIGDIHFPVVNA"
     gene            complement(25348..25608)
                     /locus_tag="ACL3GT_000986"
     CDS             complement(25348..25608)
                     /locus_tag="ACL3GT_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HGR0516664.1"
                     /translation="MKRFIAIWILLSAGLNIWQMDRIRDLEEKKPMVIYKADNAGVEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYDKVKVGDEVLL"
     gene            complement(25605..25727)
                     /locus_tag="ACL3GT_000987"
     CDS             complement(25605..25727)
                     /locus_tag="ACL3GT_000987"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516665.1"
                     /translation="MAIGEIIVGSDGKTTTAILEIPDQSFYLEIELKLKEEVIN"
     gene            complement(25766..26269)
                     /locus_tag="ACL3GT_000988"
     CDS             complement(25766..26269)
                     /locus_tag="ACL3GT_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HGR0516666.1"
                     /translation="MNVQRLIEKYKKLEGVWDAEGAELARQIFLQDLEQLDKPKPVKV
                     PQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLNGYEVEKE
                     KRYLVKIKGNIKENMLVYGELLERYFFTKSFSLDDAIYSHTRKELENAKIGWVFDCEG
                     FEIEEVE"
     gene            complement(26271..26588)
                     /locus_tag="ACL3GT_000989"
     CDS             complement(26271..26588)
                     /locus_tag="ACL3GT_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516667.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWVGYSPGMSQVVIAVYLIY
                     RGN"
     gene            complement(26613..26795)
                     /locus_tag="ACL3GT_000990"
     CDS             complement(26613..26795)
                     /locus_tag="ACL3GT_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516668.1"
                     /translation="MADYALYQGDMFVTLGTLAQISSETGITERMLKYYTYTSHQRRH
                     PNGRAVIKIEEEDNEN"
     gene            complement(26811..27242)
                     /locus_tag="ACL3GT_000991"
     CDS             complement(26811..27242)
                     /locus_tag="ACL3GT_000991"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0000400 - four-way junction DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008821 - crossover junction DNA
                     endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HGR0516669.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRARLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEIEVMKSLSI"
     gene            complement(27239..27568)
                     /locus_tag="ACL3GT_000992"
     CDS             complement(27239..27568)
                     /locus_tag="ACL3GT_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516670.1"
                     /translation="MASKINATERIAIIIEKQKIEVVTTLNYDMSISFDNKDTAPTLD
                     DNGDLFEPVYKCKVKAIPKNDVFFTSLTRVKSNIKTLQEVKKFFEFVNENRENLFEMA
                     GFKGALE"
     gene            complement(27582..27791)
                     /locus_tag="ACL3GT_000993"
     CDS             complement(27582..27791)
                     /locus_tag="ACL3GT_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516671.1"
                     /translation="MEWTDWVDWKPETKTDIKIKIENDGYTFPHYDKKNNGVKYVIST
                     LDIKRDCLRLGVPFEDVYPLQTTLF"
     gene            complement(27793..28488)
                     /locus_tag="ACL3GT_000994"
     CDS             complement(27793..28488)
                     /locus_tag="ACL3GT_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HGR0516672.1"
                     /translation="MEIDKIIKKDVLEFMETIPDNKIDLIVTDPPYLINYKTNWRKEK
                     HKFSNVIKNDNNPELIKEYIKECYRILKDDTAIYIFCSFDKVDFFKKEIEKYFSVKNI
                     IIWRKNNHTAGDLEAQFGKQYEMIILANKGRKKFNGERLTDVWDFKRVSSDKLLHQNQ
                     KPIELIKRCIVKHSDVGDTVFDGFMGSGTTALAALETDRHFIGTEIDEYYFGIAEERI
                     KNHNAQLSLFDEV"
     gene            complement(28501..28917)
                     /gene="ssb"
                     /locus_tag="ACL3GT_000995"
     CDS             complement(28501..28917)
                     /gene="ssb"
                     /locus_tag="ACL3GT_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGR0516673.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFQSWRGTADIIAQYCSKGSLIGIIGRIQVRSYEKGGQRRYVTEVIAESVVLL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            complement(29012..29347)
                     /locus_tag="ACL3GT_000996"
     CDS             complement(29012..29347)
                     /locus_tag="ACL3GT_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HGR0516674.1"
                     /translation="MIKTVFFSCDYPHHEVIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            complement(29340..29663)
                     /locus_tag="ACL3GT_000997"
     CDS             complement(29340..29663)
                     /locus_tag="ACL3GT_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516675.1"
                     /translation="MDIRKISDSVAIYSDGKKLQVIHNLGDEFILDFNVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEIFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            complement(29666..29827)
                     /locus_tag="ACL3GT_000998"
     CDS             complement(29666..29827)
                     /locus_tag="ACL3GT_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516676.1"
                     /translation="MTEIEKISEELAEYGVPDELIGKIEDLLATLYGEKKEIGDRKIL
                     DISPESMGR"
     gene            complement(29830..30870)
                     /locus_tag="ACL3GT_000999"
     CDS             complement(29830..30870)
                     /locus_tag="ACL3GT_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HGR0516677.1"
                     /translation="MQELQVKVTQAQVEIIDREKFEQNINEVVAKYQNYTVTAATIKD
                     DKQTLADLRKLDKQVSDERIRNKKVLSEPADEFDKYVKNAIQPLKDIITKIAGDVKEF
                     EEHQKAVRIDTVKGYLANKSAEYMLDPRLFDEKALEYVKASDFMADGVTLKKATMKSL
                     DDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEVFGQIKADYEFE
                     KQKEEIRQAQERAERESQELLAAQQTKQQEQAPKSTETPNFDPETGKILDGGQILQNE
                     PNALRGAENDLKRYAQKMTLEVYFVDTAEKDRFKAGLSQLGFDFKKNYQVRGYQRIEP
                     LTQAELNEQCGW"
     gene            complement(30880..31644)
                     /gene="bet"
                     /locus_tag="ACL3GT_001000"
     CDS             complement(30880..31644)
                     /gene="bet"
                     /locus_tag="ACL3GT_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HGR0516678.1"
                     /translation="MTNNQLATQIKRDITTDPSLLTGADIKKYFDPQNLLTEKQVGQA
                     LALCKGRNLNPFANEVYIVAYQNNSGTEFSLIVSKEAFMKRAERCEGYDGFEAGITVM
                     RNGEMIEIEGSLKLPEDILIGGWAVVYRKDRSHRYKVTVDFNEYVKTDRNGNPRSTWK
                     SMPATMIRKTALVQTLREAFPDELGNMYTDIDGGDTFDAIKDVTPQESREDVVARKMA
                     QIDQFKKEQEANHADPEPTQNEDPIQGELLDGELEY"
     gene            complement(31656..31886)
                     /locus_tag="ACL3GT_001001"
     CDS             complement(31656..31886)
                     /locus_tag="ACL3GT_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516679.1"
                     /translation="MTQMTNKGKSFIRAEISEKQKEYIRLLAELRGVTTQELLGQVVE
                     RFIDRNLQLIQDYKNELDDLNSKSRRRIDMNT"
     gene            complement(32006..32149)
                     /locus_tag="ACL3GT_001002"
     CDS             complement(32006..32149)
                     /locus_tag="ACL3GT_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516680.1"
                     /translation="MTKIEIENRVWLLANHEEKNELLDLGLTSKARYVKRVLELGKVY
                     AHV"
     gene            complement(32136..32396)
                     /locus_tag="ACL3GT_001003"
     CDS             complement(32136..32396)
                     /locus_tag="ACL3GT_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516681.1"
                     /translation="MFKALKTIKKIKQLQKEMHDVSLAFLALQDVGLMPETERSKAKA
                     QTMHDVSHMIKDVLDGKSVDEAMKRLNSEVKIEEVEQEDDKD"
     gene            complement(32389..32604)
                     /locus_tag="ACL3GT_001004"
     CDS             complement(32389..32604)
                     /locus_tag="ACL3GT_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516682.1"
                     /translation="MKLLTKLKLRLEGVIKSVNLDWREVAIEVSNDLLEERKRRFMRE
                     QENHDLKQELAAYKYKENFDKKGEQYV"
     gene            complement(32604..32765)
                     /locus_tag="ACL3GT_001005"
     CDS             complement(32604..32765)
                     /locus_tag="ACL3GT_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516683.1"
                     /translation="MKRKKEQWKPRIVNIMADGSQVDDLTGYVIPAGHSYYDIILGMN
                     KQSNEEGVA"
     gene            complement(32830..32973)
                     /locus_tag="ACL3GT_001006"
     CDS             complement(32830..32973)
                     /locus_tag="ACL3GT_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516684.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     KTV"
     gene            33092..33283
                     /locus_tag="ACL3GT_001007"
     CDS             33092..33283
                     /locus_tag="ACL3GT_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516685.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            complement(33561..33911)
                     /locus_tag="ACL3GT_001008"
     CDS             complement(33561..33911)
                     /locus_tag="ACL3GT_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000347962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HGR0516686.1"
                     /translation="MDFTAVGIMMVVLANHPNWQVYPDEIAKRKGVNRKTIDKYFKIF
                     EEAGYLRKIRKKPPGNGGSHIFRFFSDVKISDFQFDIMKQRLNLSIKKASMNYNSDIP
                     KSEMSESEMSDFGH"
     gene            complement(34051..34239)
                     /locus_tag="ACL3GT_001009"
     CDS             complement(34051..34239)
                     /locus_tag="ACL3GT_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0516687.1"
                     /translation="MQGERLRKWREKEKMSQEELAEKSNVSRTTIHLIESGQSSTVKI
                     RTLQKLAVVFNKQVKDFF"
     gene            34312..34518
                     /locus_tag="ACL3GT_001010"
     CDS             34312..34518
                     /locus_tag="ACL3GT_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516688.1"
                     /translation="MTDHQLETSLIVLGKEFDRTKKNGKESFSVHVSFFDGLDANQHL
                     QEFARQYPVRIARLKPDQITFLIK"
     gene            complement(34743..34913)
                     /locus_tag="ACL3GT_001011"
     CDS             complement(34743..34913)
                     /locus_tag="ACL3GT_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516689.1"
                     /translation="MKEKLNEFLKFRSQFTKREWIEINQVVEARLNEKADQLKLDDSD
                     VEIISKRLGRSI"
     gene            35112..35561
                     /locus_tag="ACL3GT_001012"
     CDS             35112..35561
                     /locus_tag="ACL3GT_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516690.1"
                     /translation="MNNFSFIETLAIAAIPAFVSGMWSYIAAKGNSKHEIDKINIAHS
                     QELENVENQFKQDMEKMQKQHSQELYSLQQTHELRLLELEKVSQLDTQTDQGLKINDL
                     IFKAISGEISADVAIKNMSTLSHFANKQQPSDLQKQFVKKLSKKNHK"
     gene            complement(35552..35719)
                     /locus_tag="ACL3GT_001013"
     CDS             complement(35552..35719)
                     /locus_tag="ACL3GT_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516691.1"
                     /translation="MNESFLTILGISMIASFITNLIAYLAGKHHLKKKIKNHKMWFDS
                     EIEHIKKKYHL"
     gene            complement(35794..36069)
                     /locus_tag="ACL3GT_001014"
     CDS             complement(35794..36069)
                     /locus_tag="ACL3GT_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516692.1"
                     /translation="MNTLNEKAINIFKAVAKETLIQGTYEENFLYSKLEAFCTNCRQF
                     AFGWTDLAEEIECQERYLLDAGFTQDEIDDIRFDASFVGMMDKMNVA"
     gene            36226..37014
                     /locus_tag="ACL3GT_001015"
     CDS             36226..37014
                     /locus_tag="ACL3GT_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0516693.1"
                     /translation="MKLGELLKSYRTEHKLSMDAFCELSDLTKGYISMLEKNEHPKSK
                     KPIVPSYDTIEKIAKGMQISTDDLINMLDDEQEIQINATPAVLSKSQIQSIYDELEPN
                     GQRKVVTYAEKLRDEQEKRKKAKINEVSENIIRLDDYRQTTYRRVTGVVSAGSGSIQD
                     DDLDMEVSFYEDEIPDDYDAIAYVVGNSMEPKIKNGDYLFIKNTQQVDYNTIGIFQVD
                     GANYVKKLRQGYLESLNPDYEDIHLDESNDIRTIGEVVSVYREK"
     gene            37016..37780
                     /locus_tag="ACL3GT_001016"
     CDS             37016..37780
                     /locus_tag="ACL3GT_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HGR0516694.1"
                     /translation="MSKENPYFEQTKQNYIEVEKLYKLGKAKHTSSKYRFLAPAVKRQ
                     SEQFLFEAKTQKRKYWKFSRGSLIFVEFGVNIGGELSNNHWAIVLDKVDSPYKKTLTV
                     IPLTSKNQIDTVLIDEIIAEYPSILLDEYIEKLHKELFAYLKYLDSNNAITEAALSDV
                     YQAYTEQFSNEIIQPKIVDDDNLKRTQSEITDIIELTQYYKKYIKRSYAKCNNLQTIS
                     KDRILKKNRLDPIGKMKVSDNTLDKINEKLKELYLF"
     gene            38087..39532
                     /locus_tag="ACL3GT_001017"
     CDS             38087..39532
                     /locus_tag="ACL3GT_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HGR0516695.1"
                     /translation="MITTNKVAIYVRVSTTNQVEEGYSIDEQKDKLSSYCDIKDWNVY
                     KVYTDGGFSGSNTDRPALESLIKDAKKRKFDTVLVYKLDRLSRSQKDTLHLIEDVFIK
                     NGIEFLSLQENFDTSTPFGKAMIGLLSVFAQLEREQIKERMQLGKLGRAKSGKSMMWA
                     KTSYGYDYHKETGTVTINPAQALTIKFIFESYLRGRSITKLRDDLNEKYPKHVPWSYR
                     AVRTILDNPVYCGFNQYKGEIYPGNHEPIISKEEYDKTQSELKIRQRTAAENVNPRPF
                     QAKYILSGIAQCGYCGAPLKIMLGVKRKDGSRLKKYECHQRHPRTLRGVTTYNDNKKC
                     DSGFYYKDKLEAYVLKEISKLQDDADYLDKIFSGDNAETIDRESYKKQIEELSKKLSR
                     LNDLYIDDRITLEELQSKSAEFISMRGTLETELENDPALRKNKRKADMRKLLNAEKVF
                     SMDYENQKVLVRRLINKVKVTAEDIVINWKI"
BASE COUNT        10757 a         9089 c         6903 g        12803 t
ORIGIN      
        1 ctcactcttt tctatctcat acatctttac cgaatgcaac acgagatcac gatacttcca
       61 agtgctgacc agatactcaa taacctcttg gtcctctatc ctgcattcca taagtaataa
      121 tagtttgacc gtgtattcat tcttcaaaat cggaacctga taagtcacat ctacccaatg
      181 ctcaaaacct aagtctgtct gctctacatt tgctagttca atatttaaaa tcttcatttt
      241 tattcctcct acttatctat tcgtaaaaga agataaaaag ttatgaaaaa atcattactt
      301 ttttaattca gacagtactt tcagagcaat tttgttaatg tcaacaaaat tggcaaccaa
      361 gcgatttaat actatttgtt gacgccaaca agtcaatttt cagacaaaca aaaaaaccgc
      421 aagcctgagc ctgcggtgaa agaacaattt agaaagtttc ctttctattt atttaactgt
      481 aatcaagcca tctggctcta ctgtgaactc tggtttatct gccatcgttc cgtctggttt
      541 gatgtagtac cagcctgttc cgtccgctga ctggataaag gcatttgata ccatggcgcc
      601 ttctttagcg tctaagtagt accaagtgtc cttgtacttg acccagcctg tcttcatggc
      661 accttctaca tcaaaatagt accacttctc agcgattttc ttccagcctg tagccatttc
      721 gcctgattgg tcaaagtagt accaattacc gtctgtgtgc ttcttccagc ggtctgaaag
      781 catatagcct gagccatcga aataatacca ggtaccgttg attttctcaa acttatcttt
      841 tggataagag ccgtctgagt gtacgtacca gtagccagtg tcattcttct gccagcctgt
      901 ttcaatcgtc aagccgttct caatatcatg cttaaactgc tcacggctaa tgccccattt
      961 tgccaagtaa gggtatggat ccacatggtc tgagtggttg tttggttggt tattcgtgca
     1021 atactcgtgc gttttaattc cagctaaact ccctgtatca agcgttttcg gcaaacctgc
     1081 ttcgtccgct agattgcgta gcaattcgat atagaggcga tagtcagcca taaactcttc
     1141 cttagttgaa tggctttcaa tcagttcaac cgctgcgtaa ctctcagcat tccaaccgcc
     1201 cccaacatcc caacttccgt tgttcacagg tcctacttgc atgacacggc catttccgac
     1261 aacatgtgaa aagaacccta gttcagggtc ctttctatag tggtaatcag cctcattttg
     1321 agctgttgag ttacggttgc ctgttgagtg ggcgtgtact tgtcgataag gctgcacccc
     1381 aacctgtggc aagcctgttc gtagtctgtt tctatcgata tccattactc ttgtcctttc
     1441 caagcgtcgt tcatctgctt cacggctgac tccacaaagg tgtctaagtc cttgtccgtc
     1501 atactgatat tgtattttgt aagctcagca cggactttag cacgagcctg tgccagtttt
     1561 tcatctccct tgtagccagt ttcagcagct acctgctcca cggcatttac tgcatttttg
     1621 gccaagattt caacaatctt gatagtcttt tctccacctt ttttgacgag gtattccttg
     1681 actgccctaa ctacaacccc tgccaaaata acaaggatgc tgattgctcc attagtaatg
     1741 atttcagtaa tttgttgcat ttgttattct ccttttttcg tatcatcatc tttttcaagt
     1801 aatcgctgaa atacttttac aatcggctga aaaagagtaa catttccttt taatttgcgg
     1861 taattttcaa tgagagattg aaaagtaaat gcgatgtacc cgagatagat tgagtacaag
     1921 aatgcaaaac ctgtcttttc aggcaacaaa acggacgccg gaatgaggat catcagtaag
     1981 agaacccctg aaatcttacg aaggagcccg ttaatgccga ttttgctctt gtactcgatg
     2041 tcaggattga taatcgccgc aatcgtccct gtcacaaaat caatgatttc cattgagaca
     2101 atcagtgcta gagcgtacaa gaccaaacca tcttcagtct gtacgacact tcttagaaaa
     2161 ttgaaaaatt caatttgcat acacacctcc tattctttag gttttaccgt tggatccgtc
     2221 cagtcaggat tgccctctgc atcaaatttc atgatataga attcatgatt caacagaacg
     2281 gctacgttga ttgttgcgat tgtaccaccc cactgattga acgcccaaac ggtttcaaca
     2341 tccttgaatt ggcgacggcc atttacaatc acaggacgtt tttgaacgtc acgatacata
     2401 tagaagtcat cgcttacatt cttgcaacga atgaactctc cattttcttt catgtagcgc
     2461 aaagcactcg caagatcaaa tggttctgtg atttttgtaa ggtctagtaa gttatctgtg
     2521 ttttgaattg tttctgccat gtctattctc ctttgtctgc tggtttagtt tgttcatcaa
     2581 gcagagcttc cagctcatcc actcgtgctt gaagtctttg attttcttcc ctttgctcat
     2641 ccaactgaat actcaagata ttacttgtaa tcatcgaatt tgttgaagtt gttgatattt
     2701 cactaattgt cattcgtaag gcttggttaa gctgttctgt gttcattttc taagttctcc
     2761 aatctgtgtg ttcgttttct attttcaaga gcaaactcct gaattgcttt aagtgcgata
     2821 ttggtcaaca tgttgttatt catgctattg ttttctccat tttttctatt ttttgattta
     2881 attcttgaat agccttgatt aagtaaggaa ctaaagcggt atagtcaata tgtagatagc
     2941 catctggatt ctcaggatct cgtgagacaa ttcttggaac gatggtttca gcctcttgag
     3001 ctattagacc aatctcctca tgtttcttat tttcgatgaa atcaaatgca accattctta
     3061 atctgttgat tttatccaag gctttcacag ctgtatctgt gatgttctct tttaagcgtc
     3121 tatctgattt ttgttccatc caatacttca agctaccgct accgacctga ttccaccaaa
     3181 caaccgcatt ccttccgcct ttgggattcc aaccatcacc aagcacatct ttacttccaa
     3241 gttcgatacc atttgaaaac acaggagaac gagaaaaagt agtattccca tagaagtttg
     3301 ctctcgatga attcgaaaaa tccacttgat cataaaaacc gacttcattc ctacagtaca
     3361 ttttcccatc agtattgacg ttccatgctt taggtccggc atagttccaa ttatttcccc
     3421 agttcgccca gaaggctgtc cggactccat gcccggcacc attccccata ccaacagaga
     3481 actgattgac acctgaaatc cagcgaccgc caccctggtc aaattgacca agtgtgaatc
     3541 caccaattcg gccttgatag gcttctagga aggttgagct agaaatgacg gactcaacct
     3601 taatagagaa gatacgttta gatgtcagtc ggtcaataaa agcatctttt gcagttaatt
     3661 ttctaataag cgcatcgtca actttcaact tctcagcagt taccgcttca gcttctaata
     3721 tcgtagtcgt gaccgaacca gcttcaaaat tggccgtttt gagcttatca accatggcag
     3781 acttgatgac tgctctgtca atcagggtct ctccagtgat gtgggtcaat ttcccaacta
     3841 agcggttatg tccattggcg ccaagattga ttccagagat gatatctcca gccgagttga
     3901 tgttttcaac tacccatgag ccagctagtt gagtcatttt tgtttgcgtt gcttcaagct
     3961 tcttattcgc atctgcgact gcatcttctg gatgtggttg ccatgttcta gatttataac
     4021 ctttgtacaa gtcaacttct gtaatataca aatcagctgt tcctgatgat gagccattgt
     4081 tatcaaaacg aatgtaagca ttatccattt ctccggaatt aaaagttact gagacatctt
     4141 cgcatctaga ggtagatagt ttcttgctgc taacaacttt cttaacgatt gtgaatccat
     4201 cgctctcgcc tgctcttcgt cccaaaatat aaacatcata gcttgctaga gcactgttgt
     4261 taaatcctct aaaattcagt acatagtcag tatttcgttc aagattaaaa cggtgactat
     4321 acaaaaagtt ttcgttttta gttgcattac ttaaacgcat aaggtctttc tgcccgttgt
     4381 gataaaagct atgcttaacc aatcttccta aattttgagt tgagccccat tcattcgtac
     4441 catttttaaa atcactattc ttaatgaggt tagggccgct tacactatat ttcccaacct
     4501 caacctgaaa cagttgattg gtcagagcca tgcgagcaac cttatccgca attccatttt
     4561 cagtattgcc caaaatccgc tcgtaaagtt tactggtttc cttaacacgc tggaagtcag
     4621 tagtctctac ttttcgcact agttgattgg tcacattcgc aaattgacta tcagcattcg
     4681 ctttgtttgc agaaacctga tcagatattc tacccatttg tcgttcagca ttatccttgt
     4741 ttgtagcgac ctgagtcttt aaatttgaaa tctgattatc tgcgccttgt ttattactgt
     4801 ttatccgatt tgaaagattt gaaatctgag tagtggttcc ttgctcactg cttgtaagtc
     4861 tatttgaaag gccactgatt tgaccgccca catcttgctt ataagtagtt atctgacttg
     4921 aaatatccgt gaacttacca tctacagatt gacgatagct agcgatttga ctagcgatgt
     4981 ctttattcgc actagtttta acagcttcaa tcctttgatt gataccctta acatcttctt
     5041 gataagtagc cttaccaacg aaatcacgat tgaccagctc acggactgct gtcgcttgtc
     5101 tcgcgctctc ctcacgagta tagcgctgta gggcttcctg tcgctgaccg tctttattta
     5161 catattcctg aatagctgat aagtcggttc gcaagccctg agctgtccgc tcaaaggtag
     5221 ccttagcttc agtaatgaga ccatcagcgt cctcaggcgc aggactccag tccgtcgcca
     5281 cactaccgat ttcaaccttg attcctgtta cccaagctgt accgcttgta gcaccttcaa
     5341 gattgaatcg caatgatgtc ttcaattgat caaaatttgt tttttcagag tagtcataag
     5401 tgaatgtaat atatttccaa tctgccgaac ctttatacat accaagcgta gcataatctg
     5461 gaccactctg tactccggtc tcactatttt ttctaaaaag ataatgtttg aagcaattaa
     5521 atacattcca aaaatttcga ccttggacta cattttcgta cttgatccaa gcgctaaaag
     5581 taactttttg gtacaacctt gagctgaaat ctggttcaag gttgaacgtt aaagtagagt
     5641 tgttctctag cctatagcat tctttttgac ctgtgacgtg gttttcaggt aatttttcaa
     5701 ttacagctcc aaccgtcttg gattttatcc atagattccg tcctcccacc ttcatttttg
     5761 aaaattcttc acgcaatttc ccagcttcag atacaactaa agtcttatct gctttatcct
     5821 tggttgcgtt caggatttcc tgacggatag agccagctcg cacctcaaat tcagcctgac
     5881 tcaacttctg atttagtttg ttctgcgtgt ctgtctcaag actcttcaca gattgccgga
     5941 tattttcagc agtcacattg agtgagctga tatcggcttt ggttctaagg ccttcagtca
     6001 gacggcttac accagcgtcg agtgagttgg ctcgttgttt gaaggtcgat tcaactgttg
     6061 aaatctgacc ttctatatct tcaggagctt ctgaataaga agtatctaca tcgcttattt
     6121 caaacttcgg catccaaatc caaacggttc cttcctggtt gaaattgaac aaccattcat
     6181 ttgtggtctg cttggattcg tttgtccaac cttttggaat atggacaaca tatcgtttaa
     6241 tttctgtcga caatgtcaca tttccagttt tatatccgat attccctaat cgagatctta
     6301 gcattattcc atttttattt gccttagcat aaaaactaat ggttacatct tgattagtcg
     6361 tacttccggg aattactttc ccgaattgac ccagagctgg ataagtaacc ttgggattac
     6421 ctccatcacg gccagatgga ttcaaaccta taattttaag agccttgtgt ccaagatact
     6481 tactttcgct atcgatagta gccgtatatg tactcgttgt ccaaattcct gtttttggaa
     6541 tatcctgctt gaatagtgag ttcaagaata gatttcgacc ggatgcctgc acactcgcaa
     6601 tccgactagc cagctcctca gctgtctgcg tgagttctga cttgctggct ttatccttgg
     6661 ttgcgttcag gatttcctga cggatagagc cagctcgcac ctcaaattca gcctgactca
     6721 acttctgatt tagtttgttc tgcgtgtctg tctcaagact cttcaccgac tgcctaatat
     6781 tttcagcagt cacattgagt gagctgatat cggctttagt tctaaggcct tcagtcagac
     6841 gattcacacc agcggcgagt gaatcagcac gctgtttgaa ggtcgattca actgttgaaa
     6901 tctgaccttc tatatcttca ggagcttctt ttgagcttgt tgccaaactt ccgtcttcca
     6961 gctggggcgc aagaacatct aaatattctc cgacctcagc atttacgaga tacacatagc
     7021 caattgatgc gactccagcc ctatttctag cgctagtaaa cgatagcttt gtccaatttt
     7081 catcctttaa tgtaaagatg ggcgaaatac ccgaattatc attgacttgc caataagttt
     7141 gtagcttgac cttttgacct cttctgcctt tgacccaaca agacatcgtg tatgtgcctt
     7201 gcgagatata aaatccatct tgagcaatac ctatttggtc tctagcattg cttgaggtca
     7261 atcgtatcgc tttatcaaag ccagttgctg gactgtctga tacatcaatc gtctttgccg
     7321 tcccagcgcc tgacggtcta aaagtacctg atgcccacaa tcctctggct aacatcatgc
     7381 gctttgtacc ccggatataa ttcctacccc cgacctgcac actcgcaatc cgactagcca
     7441 gctcctcagc tgtttgcgtg agttctgact tgctggcttt accattggcc aagttggtca
     7501 gttctgacag tctacgagtc gtcgtctcct catacgtcgc ttgcgctgac ttcacgccag
     7561 acagttcatt cttagtccga ctaagtactt caacttgctt ggcaatctca gcttcagcct
     7621 gtgcttgctt cggtcgaata tcgtttgcga tagttcgttt tagaacatcc aagtcacctg
     7681 acaaagccgt ctgagcgctc gtagtctgcg acttaaacgc ttcaagtcta gcaacagaat
     7741 ccagctcaat ccgcttagct tcctgtgcaa gcagggtact tgcgccagcc agttcttttt
     7801 tggtctgaac aagtgcttca acttgcttgg caatctcagc ttcaacctgt gcttgcttcg
     7861 gtcgaatatc attcgcgata gtccgtttca gagcgtccaa gtcacccgac agagccgttt
     7921 gtgcgctcgt agtctgcgac ttaaacgctt caagtctagc gacagaatcc agcccaatcc
     7981 gcttagcttc ctgtgcaagc agggtacttg cgccagcatt tcgcaaagct tcctcagcct
     8041 tgctcttagt ttctttcaat ggcccgttgt caaagctatt aaatcgctga ttgatagtgt
     8101 cagacagttc tctcttgact tcttcagctc tggctttggc cagttctact tgatcgttaa
     8161 agtctttttt gattttgtcg accttttggt caaaatcttt atctgttgct tcaatctgcg
     8221 cttggatttt cgcttcaatg ccatcttgtt gctttatctg cttggtaatc gtaccctcgt
     8281 aagaatactg ggtatcgttt ccagccttac tatctgcact gatacgacct ctcagaccac
     8341 ctttaaaggt aaagctctga cttaacacgg gaactttaaa agtctctttc ttgttggtct
     8401 gaatggttac ccactgccca acctcaagta acaaatgtcc ttggtagttg agattatacg
     8461 gatagtaagt taggtttttc agtttgtaat acaggtcatt taaagcgctc tgggtcatga
     8521 agacattgtc cagttccaaa gaccgacctg tcttcatacc gaccgtcaga gacttcttgt
     8581 ccgtcttaca agtgatacca gatatctgat actcaatctc actcttggtc aagccatgca
     8641 agaagtaact gtcagcgttg atcgtgatat tggactcagt caaatcacgg atttccatct
     8701 tgccttctct gttgaagaaa caagacatcc caatcatctg agtcatagcg ctcagcatat
     8761 ccctaaagga aagtttcttg ccctcaggaa cttgctcaat atgataacgc atcgcgctga
     8821 ttccgaaata gtcattcgct aactcaatgc ctgttttcag gcagatttcc tgaataacct
     8881 ctcgtacttc agctgggaaa tgcaaatccg tcacgtactc acgattgagc ttaaacatac
     8941 cgtccataag ttcaagtgtg gttgtgttgc ggtttcggtc aatctcaata tcgttgatga
     9001 agtattcccc catcttgacc cactggtagg tatccccaac cagtagacca atctcagggt
     9061 gcagggtatc cagcttattg aacgtggtaa tgatactggt aaaggtaatt ttaccgctac
     9121 cagcgcaggt tccaccaggc ttataagtat cgcccttgat gtagccatac tcaaaactag
     9181 cctctttgat atcccgtgaa gcatattcac caacacgaat agccagcgtc ctttccttgg
     9241 caaacatggc tctgtcaaat tgtcgtctag ttaaagcgtc cattttctta cctctctacc
     9301 agattaaatt tagcgccaga ccaaggttta aacttctcag taaaggtata gctaggagct
     9361 gtcctatcac cgacatagaa agtctttgtg acttggccat ccatggggtc tggataagat
     9421 acctcaaaaa atttagatga tacagcatgt aaaagctgac ttatttctcc ctgagtcatc
     9481 ataccccatt cacagtctag tttgcgtttg gtcgtgatac ggtcacgcac catgtcgcca
     9541 ttggcattac gccctgtctc tccatcgata tcttgaatac cgacttgaaa agatttggga
     9601 ggcttcacag ccaccccatt gattgtcaat tgtgccattt aacctcctaa atcttgagca
     9661 aggtttgacc tgctcgttca tgttccttgt tgatttcttg gatggctacc cgtccgaact
     9721 catggcctgc gatttggata acgatgtcgc cgtcgccaga gaatccacct tgtggactaa
     9781 caccagccat ggcatttact accgcactgc tgactactcg tccaagtgtt tggataaatc
     9841 ctgtattttc aagtggtacg accgcctctt taccagcttc accaatcatg gcgattgttg
     9901 gactatcgac gataccacca cgggcaagac gagggaggct aactgtactt acactaccaa
     9961 cccatcctag accaggtaag tttctgacaa cgcctaaaac tccattaatc attccgatga
    10021 agccattgac tacattttca atcgttccaa gaaccgcatt gaccgcactc ttaaacgctc
    10081 cacctactgc ctcgccgacc atctgaccag cattaacgaa gatacttttg acagtatccc
    10141 aaacgccttt aaagaagtct ccgatagagc taaaggcatt tttaacagcg tcaaaagctt
    10201 ttccgaatat atcgccaaac cagcttgcta ctttggaaag tgcacttgta acatcgttcc
    10261 atctctcgcc aaaccaagaa cctagtttgc taaagatgtt tgttaagcca gtccatgctt
    10321 tttggaacat gtcagtaaac catgccccga tattagccaa cgcactagtc acatctgccc
    10381 aacgttgtcc gaaccatgag ccgattggtg tgaagatatt aacgatagcg tcccatgcac
    10441 cttggaatac accagagaac cactctccga tgccagagaa tatgtttaca atggcgtccc
    10501 atgcttgctg gaatttctcg ccaaaccatt gacctatcgg ctcaaagatt tcttgtagtt
    10561 tcgtccatag accgctgaaa aattcgccaa tcgcttgaca aataccactg ataaaatcac
    10621 atagtccttg ccatgcagtt ttagcaaact caacaacagt gtcccagttt tgatagagca
    10681 aaacaccaat agcaatcaaa gctgcgattg ctgcaataat ccatgttatt ggacttgtca
    10741 aaactgctaa cgctgcatta aaagcccatg ttgcagctgt agcgactcct gctgcaacag
    10801 aatgtgcaaa ttccgccgcg gttgctaatc ccattttcgc tgcatgagca gtccatgcta
    10861 gagctgattt accaagttct aaagcagttt ttcctagctg tgcaattgtt ttacctgaat
    10921 tgaccacaaa atcttttgca tataaggtgt tcaaatagat tgtttcagca aaactgacca
    10981 acttatcaaa tgtcaatgct ttaatagcaa gacctagatt cttaattcct ccaacaatca
    11041 aagagacctt actacctaac aagctgaatg ctcctgcaag tcctccagct tgttctgccc
    11101 atgataagaa attaatcgtt tgccaagttg ttatcaaagc tacgataggt tctttgtttt
    11161 ctttacacca gtcagaaaaa acggtgaaac catctgccac taacttaata gcatccgcca
    11221 atagtcccaa agtggctaaa aggccacctc ctaataaatc tgaaattcct tcaatactaa
    11281 caccgaatac tcctgataaa aactcagcaa aaggttgcca ggaattctcc cagagaatct
    11341 gaataatgtc aattagccca ttaaaagcat tagcaataga gttaatagca gggactacat
    11401 gttcatcata aacacgactt aagccatcgc caaatttgtt aacagacctt tcaatgctct
    11461 caaatacagg cgcaacagta tctaataaac tttggaagac tgatgaaatt ttaggagcgc
    11521 ttgtcacaac gactttttca aaacctttaa acaaacttcc tgctaattta ctaccaactt
    11581 caacaatggt agatgtcaaa ctcaacagag ttgacacaat agcgctaccg atacgaaccg
    11641 caccagttga ggtaatgacg tcgtagaaag cactagaaaa gtcctgagct atgtttccta
    11701 ctgcctcgga aaggttacca acattatcaa acaaagcgac tagcgccctg gtaatgcgtt
    11761 ctttttgcct tccaaggcca tttgcaatac tttcggcaag gaaaacaccg atacctagcc
    11821 cgatagtagc tattgagcct gtcacttgcc ctaaagcata agcaattttc tcagccattc
    11881 ggttaaaggc attcacaacc cttgggtcag tggcgatttc tcccattgtc ttagctattt
    11941 ggtctaaggc agtcttaatg cgttttatac cttctggtct aaatgctgca tcaaaacctt
    12001 tcttgaagag gtcaaacaac cctttgagct tatctccaag accatcaaaa atgctcttga
    12061 atttgttgtc catgtcagtc aactcgactt ctggcaagat gtctttgaaa ggtccgccac
    12121 cgcctccctt tcctttacca cctttgccac cgcctccaga accgcctgcg tcgtcatctt
    12181 ttggtttttg caagatgtta atctcatcaa atcccaaaag acctagcaac tctttagcag
    12241 ctttcttagc gtttttggct gagtctccaa gattgtcagc aagtcctcct gctgaatctc
    12301 cagcgtcgtc tactgcgtca gcaaggtctc ctgctccgcc tgcagcatcc ttcatggcgt
    12361 tacccatgtc tccaactgct ccaccaacac catctttcac tgttgctttc ttgttgaaca
    12421 tcaaagcaat aaactcagcg agtttagcag taacgttctt caaaaccata gcaaaagagt
    12481 tcaagacagg cataatggca ttgataatcg gtaacataga gttaccaagg ttcaatgctg
    12541 cgtccttcat cagcgactta aataggctga tacgaccatt tacagaatta gacaaggtat
    12601 tcccatactt ggctgtagcc tgttccagaa tagccataag gcggatttgt tgctgggttt
    12661 ggtaatccaa ctgttgccag ctctgtccgt ttgcgaactt cttaaaggct tcagtggact
    12721 taatcatagc cacattgacg ttgattccta ggtcctcaat tgcttcggtg ttccctagta
    12781 gacctgagcg aatccgctcc ataacgtctg taatcgtgcg ccctgaacct tcagcaacca
    12841 ctgccgatgt ctgcaacatc ttagcagtat aagcacttag cttgttggta tctttgataa
    12901 atccagaaaa taagtttgaa tagactgcac cgtagttggt agcctcaccc acacccatat
    12961 tcatagcgtt ggcgttatcg ttaacccatt ttaagaaaga ttgcgaactc tcgcccatct
    13021 gtcgcttgat ttggttcata gacgctgaca cttcaagagc tgtctgcgtt gaatacatcc
    13081 caacatcaag taatttctta ccaaggattg caaaaccagc aaacttagcc aacttaccaa
    13141 acgcactacc gattgagttc gactgttcac gaactttggc agtggcattt ttcacttggt
    13201 cagatgttcc tttgacctga ttctcgactt ctttcatctt tttcctgaaa ggcgctatct
    13261 cagcgtcaat catgaccttc aattcatcaa gagttgccat ttacttcctc cttccttttt
    13321 cgattatgtc tctctgcaaa atcacgcatc cgttccttat gcaacaaaag cgcttgtctc
    13381 tgtcgttcct gttctactgc ttgctgttct tctacaaaca actcaggcgc atattcccaa
    13441 agctcaacaa tcttagcgtc attggacagt aataaggaaa catgattagt tatcattcgc
    13501 gaaagtatgt acgagtcaat aatcttttct ttacgctctt ggattttgac acggttgtag
    13561 ctttctatca tttccctgat ttcaagcacc gttaaatccc aaaaatcaag aggcttgccc
    13621 ccgatgtcta aaaacatagg ataaagcctc tcaataatct gcgttaccgt taagattact
    13681 cgactactgt cattttcttc ttggaagttt tcttgtcctt gcttcctcgt ggagtaaaac
    13741 ccgatacttc aaatagcggc atcaacacct ctgtcatgaa tgtcgtttgg tctccgccgt
    13801 tatccacgta ttcatcgtat aggtcgtaga catcttcaaa ggaataccca tgttcatact
    13861 gctgcaaggc tccatgaact aacaacagca taactttcaa aggtggcaaa gtgaactctt
    13921 cgcctgcttc aggcatgaaa atcttcagca agttcatgcc gattttttct tccacagttg
    13981 cagcctgatg agatgtcaaa cgtagcttca actctttttc gtcagtaact ttccaagttg
    14041 tgtattttaa cgccatttaa ttaacctcca attccatcaa cgaatgtcaa ttcagactgc
    14101 aatgcaatct taagtgtgaa ctcgataacg gcattaacgc cgccaccgcc cagtttaacg
    14161 gatacttgac cttcaaaagt gaccttagta ccgtctgggt aggtttgttc aaagtagagt
    14221 tttttcttgc catctgctgc cttacgtaat acacggtaag gagctgttgc gcttgaatta
    14281 ttataagcga acttgtactc aagttctcct gcgtccccga taccaaactc gtacttcttc
    14341 accgtatctg caagagtagt attttctact ttttcgggct cgataccaaa ttcaggtact
    14401 tccttaagcc ctacaagatt ctgataattg cctttcgttt cactaaaggc caatttaatt
    14461 ccatttgcta acatgtttaa ttctccattc taaattgaaa aacaagctct gagtctaaat
    14521 caacgacacc ttcaaaacgc atgaccttat gtctcaaatg agacgggtct ggcacgtctt
    14581 ggcagtcagt tcttcgcaaa cctaaagact caaaaatctg attgatttta acagctaact
    14641 cactagtgct ggtatcatca aagatatcca ccttatagcg gatagatgat ttttgttcct
    14701 ggtcatcaaa ccaatcaccc ggcttgtttt gttcttctaa aaaaataacg actgggaaag
    14761 tctcccaatc gctaggataa gtatcggtca cattatctgc gaccttttgc aattctttat
    14821 aaataacagg cttgatatta atcattttat ttgttctctt atctttctac ggacataatt
    14881 cgaaatattc ttagacacac gctcttgatt gtctctcaaa gctggataaa gataaggctg
    14941 ggcaggttga ccatacatct tgtagaactc cccaattttt tgaaaatggt aaggtcctac
    15001 attgatttgg tcttcatgca cataccaagg attagacttg taagtcacgc tgacctctgg
    15061 agagataccc gaatggttag cttgtcctat tggtcctgtt ccaaactcaa cgtaaggagc
    15121 gtatttaagg ttggtgtaaa cttcgcctat agccttatct ccgtccattt ttgctctagt
    15181 tttgatacta gttataagct ctccatctct cgctggtgcg agtcttcttg catctgcttg
    15241 gacaaccttt atagtagcat tgtgtaccgc acgtaagacg atatcctcgc cagttttttt
    15301 actagccaat cgtctacatt tagctatgag cctatctgcc cctagtagcc ctgacacgct
    15361 ctaactccaa aacttgatga tgtgtgtaga cctttttaga aataaccctg tgagtcactt
    15421 ctgtctggct atcgatacac acaccatctt tcactttgat agtagctgac ttgttggcat
    15481 ttgcgttcaa aatatcattg acacgctcgc catacaattc agattgtaac ttgctactag
    15541 ctggccacaa ttcaaggcgg actgtctcag cttccttggc atacccttct ttcgcgacac
    15601 cttcctcagt gacagtcttt tcaaaccgtc gcattggata aggtttcagt ctactctgct
    15661 tcaaaaacat gacctgccac ccttgctagc ctgtgcatgc gtattcgctg tagaagaccc
    15721 gtagacaggc cgttttctcc gtagactact tctataccac cttcggttct agaacgctct
    15781 ccttccgctc ctgagcggtt gtggagctcg atagcaacct caggtatcaa aagacttaaa
    15841 gcaggtgtca aagatgtgcg attagtctct gacaagataa gatttgtagc tcttgtttgg
    15901 agcaacatga gaagctgagt atcttcttcg cctgttaatt tcttcagcaa ctctatagac
    15961 atttcaatcc tcttctaaga actcaggttc agggaggatt ttctcaagaa catctgagat
    16021 agcgacaccg ttgctggcaa tattgtcagc cagctcagca tagcgctcct cagtaatctc
    16081 aagttcctct cctgccagtc gtttcacatt tgattcccaa tcatagaaat cttgtttgat
    16141 tttaaatttc ataactcgga cctatttctt accagttttt tctttccagt tagttgtatc
    16201 tgtgtctggt gcggttgatg aattagaaat atccttaacc gctacataga ctttatcggc
    16261 atgagtaact gtgtcacctt ctttgtaggt tgttccagtt ttccacgctt tagcacggtt
    16321 tacaacttta ccttgagtag atggtttagc agcaggctta gaatctgcaa ttgtgatgat
    16381 gtatttcttg aagtgttcaa gaacaaatgc accagtgtaa agcaattgct ctaccaattc
    16441 gccaaatcgc cctggaatgt tatcgttgta cttagtatta tctacttgta ctggagatgt
    16501 aacaacacct ggagcagtag caagggcatt aacacctttc aggaatttag aaggaacctt
    16561 atagactgtg taatcatcca attcaccaac atatcctttt ccaaggactt tcttatctgc
    16621 gtcaccatgt ggtagacgaa cgatttcaga cttgatcgct ttgtagaaac ttggagtgac
    16681 gaagagcaag cgttcttttg taattccaag ctcatcaagt ttctcagaca catcaagaac
    16741 cgcattataa gcgttgttcg ctcctgctgt tttacccatg gcaacattgt cacttacgtt
    16801 tccaagtgct gcaccaaaac gtagttcatc aagatatgga gcgactactt ctgcagcctg
    16861 acgagcaata acataattga tattcacttg accattagag tcacgttcgt ccaattgatc
    16921 tacgaaacga ccccagtatt tttcttcatc aagggtataa accttttctt caacttcaac
    16981 gtgatcaaat tcattgtctt tgttacgttt gtagtctttc aactctgttg tgttaccagt
    17041 tgctactgta aaagagcgac cttgcaaggt tactgcatcg cttgatgtca caagcggtgt
    17101 tgaatatgaa tttactgcaa gtacatcctc aataatccca agatgtttct tgcgtgattc
    17161 tgctgtattt aattcttcaa atgccattta tttttcctct tttcttttat tacaagaagt
    17221 ctttacgcca tttttccgtg acttcttgct ggactgtttg tgcatttttg ataggtgcac
    17281 tacctttcat acgttcagag actcccttct gaactgactc ttcccatgct ttttggatag
    17341 aggtaataga ttcagatacc gtctcagcgt ttgtcaaatc gactacattt actaactcaa
    17401 caggtaagtc acgttcactt agcattgctt tagcctctgc ggtcaattcc ttacgagcaa
    17461 tagccttttc acggtcagct agttcttgct cacgctgatc caactgatat ttctgttttt
    17521 catcagcgtt catcttggcg agtttcttag cttcgttttc cttggcttct tgctctgatt
    17581 tccacttggc aaatttctta tcgatgatag catcgacatc tgcatccgtg tacttcttct
    17641 cgtcttgcgg ttgtggtgca ggttctgcag gtaccttttg ttcttcaacc gtttcgactt
    17701 cgactgtttg tgtttcttcg ttcattgcga acctcctatt tttaaagtcg tccccgactg
    17761 tataattcca tggctttttt tgtcatcaat gctcggacaa tataaaaacc gcatcaaatc
    17821 tgacacggtt tatagcaatt tacagtgatt tatagcagtc tattcctgcc agtcaagatt
    17881 ctggatcacc tcctaatctt taatggcacg atttgaaact ttggcgtaaa catccacata
    17941 agtctctttc ttgtctccat tatgcgtgat ttctgcataa tctccacaag tctcgcttga
    18001 tgtaattttg ttcgtactaa caagagcttt ccaattttgc agggtcttgc taaaccaaac
    18061 tacaaagcag tcttctgctt tgatttcacg acctgataag cgcgaaaatt cttgcgatgc
    18121 caattgtttt gctttttcta acattttatt cctccgtttt ttcgtatgtt tctgcaaaaa
    18181 tatccggctt gcatggataa tattctcctt gcacgccttt gataatataa tccccttttt
    18241 tagctaccat atcaccttca agtgtagcaa tccatatatt cccaagtgca tcaaaccaaa
    18301 tcttattttc tgcgaagtta attacctctt tatggttatt gccgttccac tgcacagcct
    18361 cgaccactac tggtttttta cggtatttca ttcctcactc ctttctgggt acgaaaaaag
    18421 cacttagatc tctctaggtg ctttagccat attgtacttc aacttcgttc atgatttccg
    18481 gtaaagtttt cccttcaatc tgtaaagaaa tcaaatcgtc aaaagaagac gctctatatt
    18541 cgttgtccgc aataataaca acaatatcat aaatagaatt agggaaaatg ccacatactt
    18601 gaccattata attaaaagaa gcgtcccatc cattatcata taacgcttgt aaatcatcta
    18661 atatcgccat aatatatctt gattctcctt tctttcatcg tctgttaatt ccctagtact
    18721 cctactaacg aacttacctt catcatcaaa tacaaaatca tgagcatgtt ctccgatttt
    18781 tccataagga tgacgtgccg gttgtttatg gtttgtaaaa tgaacatcct tcgttttaaa
    18841 acctctagca tcatagtaag ttctaccaag gacatctccg tttgtagcat tatgctgaac
    18901 tacactatta ggcaaaccta ttttgccagg cggagtgtgt ccaattgtag tccctgatac
    18961 acttactatt ataccatctt taatagtttt atcaaacgct ttacgtttaa tagactctct
    19021 attgccatcc acatacttgc tataccactc tttataagtc atatcagcag gtactagctc
    19081 ggtcttacct gtttctggat tccttgctct gcgcttcaac ttgctgtaat ctgcgtcctc
    19141 atcgtatccg acagtagtag acctacacca agggtgcata ggcggacaat tgacaccagg
    19201 gacagcctta tccctatcat agacctgatt gtcatgctcc tgacaaatgc gtgatgtacg
    19261 cttgtctaag acggccacaa agatatactt ctctatatcc gcttcctcat agttgagtag
    19321 ctccatttgg ttatgaaaaa aggctgattc tgtccgaacc aaacgccttg catcgttctg
    19381 ccccacattg aaccgctcag caattgcttg tgcagtttct cgtgtatctc ggcctgtcat
    19441 aaggcttatg agtaattcat cttttatgct tgatgtaagc ttccctgtat tcttccagat
    19501 gtttgttgag taggtacttc catctcctac ccaactaaaa gactgtagat gtttaatctc
    19561 gctctcagga agcccagaaa agccgtatgc tagtcctatc tgctgctgca ggtcaaaggt
    19621 agccttgtag taactatcct tcatcaggtc gctataaaag gcgtctgagc ctgtcttttc
    19681 tgaatgatag atagattcac gcatacggtc taaatcatca ctcaaacgtt ctagacgctt
    19741 catacggaaa gaataagccg gactatctaa gtcagccagt agtctttgga tatttggatc
    19801 attcggtctc gcttcaagta ctttacgaag ttcattcaga tttttcttgt ctttcatgtt
    19861 cttcaagact tgtctagctt ctacctgact tagaccataa tcacgttgga acttatcaaa
    19921 aatcttattg acttccttat ccaagtaagt cttggcttcc tgatagacct tatcgaactg
    19981 atctgcctgc ttttcggcct tgtccatctg ctggtaaatc agattggctt tcctcttcgc
    20041 ccaatactcc tgattcttca tcctctacct cgtcttcggg tttcgtgttg tcttggttaa
    20101 acatcggcat gtcttccatg ttcttctttt tctcttcttc caaggcttct agctcagcat
    20161 cagggtcttc cacaaacggc aagagagaaa taagctgtct attcgtcact ttaccttcaa
    20221 ggttgttcac gatctgagag atttctaaca agttcttagg caaaccacga ctgaattgtg
    20281 gaacgattga atgagactct aaagcaatct gcttcatgcc taagtaatga gcaaaaatcg
    20341 caatacgctg acgcaatcct cgcttatagt tcgcttcctt ggtcttagta atcatttcaa
    20401 ggcccatcag cttaaattcc atggctacac ctgatgtatt ccctgcgaaa ttctcatcag
    20461 tcaaattagg cacatggcta aatgtgtaga tgtcctcttt aagagctgta cgcaagattt
    20521 cagtagcact ttcgtccagc gtattcttca agaactcagc ccttgcacta tcgcccggca
    20581 attccaaaag accttcttca gaaagaatct tcattgctac cttagcgtct tctggagtgt
    20641 ctgctaactg cgtgccatac aagacaagta tagactctac agcctgttcc ttatcattga
    20701 cacgattccc catcaaggaa ttataagcgt ctatcaagct aatttgttgc tcatagtcac
    20761 caattgcaaa gtgattgttg cgatattcga taattgggat ttgaccaagg ttgtgaggtg
    20821 ttgcctcctc gctctgagtt gttcctgaat ctgtacttct cagcaccatg tgatagtgca
    20881 gattttcggt aaagacctca gcctggtact tggtagtgtc tttcgtatcg tcttttactt
    20941 catagtaata gaccgcaaac aaaggcttcc gctcaatact atcatcgtag accatgaagg
    21001 tattttctgg atcaatacta gttgaatcca actcagtcat accctcttta gcatagatgt
    21061 actcgtaagc acgaccatag atagccatgt tcaaagcatt ctgagcatct acttggtcaa
    21121 tctcagcacc atcaaaggct gtaagtagtt catcgatatc actgtcagca gtattgttat
    21181 acttaatagg attgcccata aaatagcctg tagccgtgtc tgcgatatcc ttggcatgat
    21241 tagctaccgt cttgtaattc ggtgcgttca cgttgcgtct cttgtgattt aaaatagcat
    21301 gatcacccat gtagtagctt tttaaattct tcaagcgtga gctttcagtg ttatgtatcg
    21361 ttatcaattt gtaaatcagg tctttcttca aagaaccctc atcatatcca tcccgtggat
    21421 aggttaaata ttggtacatg tctttcctct ctatagacca taatcagaac gtctgcggac
    21481 ggttgctttt ccaccttcga tacattgaag gctgtaacgc aaagcgtcca tcaagtggtt
    21541 gtttttatcc tctggtttat tcaaccagtt gccttcttta tctcgctggt agcagtaact
    21601 ataaaattca tccatgatgt ttttacaatc tggatgcaca taaatagcgt atccttgcaa
    21661 tttggatacg cctgccataa tactatcctt acctttacga ctctctttaa ttctagatat
    21721 gccatgttct gacctgagct cttcaatcag ccgtgactct gcgctatcag caatgatttg
    21781 tgagcgatga taacctttgt cctttatcat cttcgcaact tctttggtta tcaatccgac
    21841 tttatacgcc tcatcaaaga cataaatctc tttcgtcgtg tcatttatca acgaacaaca
    21901 caaagcagtt ggatcatgag taaaaccaaa gtcaagaccg atacataact tattagctga
    21961 atcttgtagt aattcatctt tattgaaatc cttgacagtc acgttttcgt agattaaacc
    22021 ttcagcaact ccccattcgc catcacaaac gattctagca cgtctggggt tcgtatgata
    22081 caaatcctca tagcgtttga tatcgacttc atcaagccac tcattgcatt tgtaagtggt
    22141 tgtagtagcg aatgtgtcag cccgtctcgt ctcttcatcg aagaatacac gcttgagcca
    22201 atgcctctca ttccacgggt taaatgtgac tgtgatttgt ttaaagaaat caggtacatc
    22261 taagctacca cggatagact caacaaccgt gctgaacttg tcttcagtct caatttgata
    22321 tgcttcctcg aaccatgccc aacaaagact gccgacatcg accgtgatag atgtgatttt
    22381 gagttcatca tccaaaccac ggaataggat tttttgacca gtcgctttta tggttatttc
    22441 aggcaaagac tcattgaatt taaacaaatg agtcaccccc aacacattac acgcccattt
    22501 aaaatccgta taagttgatt gcttatttgt attcgaatac ctacgaataa caagcaagtt
    22561 gccccaggaa tatttcaaaa gacggacaac atagtttaaa gcggttgtct tggacttctt
    22621 cgaaccacgg gaccctttga ctacacgata aagacttctt gagcgccaga actgtccgta
    22681 cccagctcct actgtcttag gtaagtcaac gacaatatcg ttttgcttaa tctggtatgt
    22741 ctgactcatt tgcaaacacc accgttccag aaacatccgc ctctacctta tccgtccaaa
    22801 gcctatgccg tttaccaaga agttcagccg ccttgattct atctttagct cctacatcta
    22861 tatccgtaat cgtctgccct agttctccaa tgcttatcaa ggtctgttct tgcgtctctc
    22921 ctcgcatgac tgaagttaga taacctaaga cctcttgctg atccgcaatc ttttcagaat
    22981 caagctgttt cagtcgttca tctatatagc ttttaatctt aggattcttt agtaacttat
    23041 gtccttcaac gcctgccact ctatcactag aaacacgata acctgctttc ttataggctt
    23101 ccgtcgcatt acctgagatg atgtactcat ctgcaaatct cttttgtttt attctcaatc
    23161 cactcaattt tccatcacca cctttcaaac aatcaaaaaa gccacacgat gtgcgacctt
    23221 cttgcaaggc gactactacc ttgcgtgcgt attaaatttt gacttctttt ttattttttg
    23281 tagtctttaa aacctctgag ggaatcaaac cctctagctt ataacttatc cggaatataa
    23341 ttagctacgc aatcatgcga ggtccagtcg cttccgcaac catttttaag ttaatgagtg
    23401 ataggagtta atgagtgata tgtgaatccc cacccagaag atttaactca ttctgggaca
    23461 caaacactca aaggagaggg gaggacttga acctccaagg ccattacagc cccctgacat
    23521 tacaggtaac catctaccaa ttctgagacc tctcttttca attcttgata ctaccattct
    23581 aacagatttt tagaaccgtg ctgttccaaa aagtcccata agctcactat gaggttagat
    23641 aacttcttcc aaagctaaga ccgcctcatt ttttaacctg tagtaggttg tacgactcat
    23701 attcaaatca taacaaacgc tatcagcggt gcctttgttg atgtaagtca ttcttaatac
    23761 tgccctgtac tttggatttt taagcctatt gatcattcta cctaattcaa gttttctgtt
    23821 aatgacctct ttagtatcct gctctatagc ctctttcatc actaccaact gagtatagac
    23881 atcatcaact tttctagtct gtccaccttg gactttaacc tcggaccatt tagggcttga
    23941 gagcaaacct gcctcaagct cgttaatttc gtctatacgg ctttggatgt ccatgtccag
    24001 atcctgcaac tctttcaaga gctctttagc cttgttcact ctctgtctcc tttgtgatat
    24061 aatagtcttt gcgagaacta ttagctgagg cagagagtgt cttggctttt tttaatgctt
    24121 aaattcgttg accaggtccc ggataaagaa cttccaatca gattctctaa acgtcaagaa
    24181 acgatctgta gtaaaatttc taagtctttt atagaaaagc atctttagtt ggattgactc
    24241 accaacactc agtaaaatac cggggaagcg atgtactgaa tgcactctat ttccgtatcc
    24301 agaaatatct aaatgtatta acgtttctgg atatatgcgc cccatactag cttcaactcc
    24361 gaactcaacc ttaacttctt ctacaattgg aacttcgtca aaaattggtc gtgcagaaaa
    24421 tattggcgac ggcgtttctt gtttttttct tcttcctgaa tatggatatt tacaaggtct
    24481 catttgcgtc ctccaaactc cttattttca tagatgttgc cgatgatttc attttcttca
    24541 atttcagtcc ataaacatac tgcgtcactg cccgtatcaa ttacccaaga accctcaagc
    24601 tgcttaacaa tccctataaa ttccttgtca tactcataga aaccgccaat ttcgtcagct
    24661 ctacccaaaa atctagtagt tcgtacaata tcgccttcaa agatttcctt tccgttcttg
    24721 tctttgagtc ctgttgattg catgagttcg atatcgtcaa aatcataaca atagatatct
    24781 ctttcaactg ctagaccact ctcgaaatag acttgttgtg tcactatttc tttgttttcg
    24841 tagtcaatag caagaatgtc atctgaaaaa aacatacgtt tttctgtttt tatccacgct
    24901 ctatatcttg gtgtcatgtt aaatcctcct aagcattaac aactggaaaa tgaatatcac
    24961 caatcactaa agagcatacg ctgtaataat agccgttatg ctctgcttca caattggcaa
    25021 tagctacagg gttctgatta tggaagatag ttactttgtt tttataacca gttccccaat
    25081 ggtcggggat ttcttccggt tctccaattt caatattagt aatcacagcg tcaagtgata
    25141 catcttggaa ctccccacct gctgaggcac agcaatcact ttcagacatt tcaatagtga
    25201 cctttgtgcc gtcttcaagc agcaaaaagt ccttatccca tttcacaata cgcttaaaga
    25261 gcaacaattc tttaagctct tccaacgacc cgtaccttgc attttcccaa tcaggctcat
    25321 aatagtctgg tagtttaata gtttctgtca tagtaacacc tcatccccaa ctttcacttt
    25381 atcgtacacg tccttcgtaa ccacgaacac accatagtca cgtatcgtta gcgtatatag
    25441 cttgccatgc cgtcctttct cgacgacttt accgaatatc tcaacgcctg cgttatcagc
    25501 cttgtagata accatcggct tcttctcttc caaatctcga atcctgtcca tctgccagat
    25561 attcaatcca gcagatagca gaatccagat agctatgaat cgtttcaatt tatgacctcc
    25621 tccttcaatt taagctcaat ctctaagtaa aagctttgat caggtatctc cagtatcgct
    25681 gtagtggttt taccatcaga accaacgata atttctccga ttgccaaaac taagtctcca
    25741 attgtgctat ttagcgtaag gctcatcact ccacctcctc aatctcaaac ccttcacaat
    25801 caaacaccca gccgattttt gcattttcta gttctttacg ggtgtgggaa tatatagcat
    25861 cgtctaaact aaagcttttt gtaaagaagt acctttccaa aagttctcca taaaccaaca
    25921 tattttcttt aatattccct ttaatcttta ccagataccg cttctctttt tcgacctcat
    25981 agccgttaag ccaagcaaga cagaattttt cgatgttatt ttcgtaaaac caatcaggaa
    26041 ctttcttatc ataatgatct tcaattactc tcattgcacc gtaaacatga aaattgtttt
    26101 tctttttaaa ttctatatat tccgccacac actgcggaac tttgactggt tttggtttat
    26161 ctagttgttc caagtcttgc agaaaaattt gacgagctag ttctgctcct tcagcatccc
    26221 atacaccctc aagtttttta tacttctcaa ttaatcgctg tacattcatc ttagtttcct
    26281 ctataaatca aataaactgc aataactacc tgagacattc ctggcgaata gccaacccaa
    26341 tcatcaaact ccttagattt tggcaaccaa tccttagtag ctcccaaatc atagtctgta
    26401 ggcttttcat cagcgaatat gcattccatc gctcccataa acgtcatacc atcttctgcc
    26461 atttcccaaa aatagtccgc ccggtctttc accgcttgtg gtaaatcttg cttgggaggt
    26521 tgcggcttcc cgtcttctac cgtccagttg tatacttcat taactttttg ctttaactct
    26581 tccatcatct tccaacttct tcactttccg tcttaattct cattatcttc ctcctcaatt
    26641 ttaataacgg ccctaccgtt tgggtgtcgt ctttggtgtg atgtgtaagt gtaatacttt
    26701 aacatccttt cagtaattcc tgtctcgcta ctgatctgcg ctaatgttcc aagcgtaaca
    26761 aacatatcac cttgatataa tgcgtagtca gccatctgct cctcatttct tcaaatactc
    26821 agggatttca tgacctcaat ctcaacctct atccgtggat ttagactgta gaacttgcct
    26881 acatcatgta gcgctatctg accgtcgtct tggaagacga tccctgacat gctgtcatat
    26941 agcgcttttt cgtagttatc tatgtcaggc tttttgccta ctggtataat ttcatccagg
    27001 agggcctgct ggttcttctt gactttagaa atgtactgag gaggtttgat ataaaatcta
    27061 agccgtgccc tcaaagctcc ctcaaggata ggctgaccca tgtactgatt agcaatgagc
    27121 agctggcaat gattgcgcca tgttttcata tccttgtctt cgtaagttgt ggtaaaactc
    27181 ccacgtcttg caaaccttgg ccgtgattga ggtttaggct caatgttcag ggtcaatttc
    27241 attcaagagc ccccttaaat cctgccatct caaagagatt ttctctgttt tcgtttacga
    27301 actcaaagaa ttttttaacc tcttgtagcg tcttgatgtt gctcttgact cgtgttaatg
    27361 aggtgaaaaa tacatcattt ttgggaattg ccttaacttt gcacttgtag accggttcaa
    27421 aaaggtcacc attgtcatct agtgtaggag ccgtgtcttt gttatcaaag ctaatgctca
    27481 tatcatagtt tagagtcgta acgacctcta ttttttgttt ctcaatgatg atagcaatac
    27541 gttctgtcgc attgatttta cttgccatgt tctttctcct gttaaaaaag tgtcgtttgc
    27601 aaagggtaca catcttcaaa cggtactcca agtcttagac agtctcgttt gatgtccagt
    27661 gtagagatga cgtacttgac gccgttgttt ttcttgtcat agtgtggaaa agtgtacccg
    27721 tcattttcaa ttttgatctt gatgtccgtt ttggtttcag gtttccaatc cacccaatcc
    27781 gtccactcca tctcatacct catcaaataa acttaattga gcgttgtggt tttttatccg
    27841 ctcctctgct ataccaaaat aatattcatc tatttcagtt cctataaaat gcctatccgt
    27901 ttctaacgct gctaatgctg tcgtaccgct tcccatgaaa ccatcaaaaa cagtatcccc
    27961 aacatcagaa tgtttaacaa tacatcgttt tatcaattca ataggttttt gattttgatg
    28021 gagtagttta tctgaactta ctctcttgaa atcccaaaca tctgtcagtc gctcaccgtt
    28081 gaatttcttc cgtcctttgt ttgccaatat aatcatctcg tactgttttc caaactgcgc
    28141 ctctaaatcg ccagcggtat gattattttt tcgccatata ataatatttt ttactgaaaa
    28201 atacttttca atttcttttt taaaaaaatc aaccttgtca aatgaacaga atatataaat
    28261 agccgtatca tcttttaaaa ttcgataaca ctcttttata tactctttta tcaattcagg
    28321 attgttatca tttttgataa catttgaaaa tttatgcttt tctttccgcc aatttgtttt
    28381 ataatttatc aaataaggcg ggtctgttac gattaaatca attttattat caggaattgt
    28441 ttccataaat tccaagacat ctttttttat aatcttatct atttccacta actgtccctc
    28501 ctaaaacggc aaaccgtcat ttgggaggtc aaaggggtta ggatcggtaa aaggtgagct
    28561 attcccattt tggaaactgt tgccttgtcc gtgctgactg ttgcgactct ctagcagaac
    28621 tacactctca gcgattacct cagtcacata tcgacgctga ccgcctttct cgtaagatct
    28681 aacttgtatg cgtccaatga tcccaataag tgagcccttg ctgcaatact gagcaatgat
    28741 gtcagctgta cctctccaag attgaaaatt gataaaatca gcctcacgct ctccattttc
    28801 gtttttgaaa ttgcgattga ctgcaagcgt gccctgtaaa ctagatacat tattaggcgt
    28861 ttttcgtaga tcaggaggcg ctacaagcct cccaaccagt gtgacgttat tgatcatctg
    28921 atttgtcccc ctctagtgct acgctctccc aagagatacc ctaaaaacat ccataggata
    28981 gccaacccaa tctctttgat aaaatcattc attatttctc tcctttgcat tcataacata
    29041 cattttgacc tacatctttt cccttgatta ttgataagct accacatttc tcacagctga
    29101 ttataaaacc taaaccattt gaattaatac tgcttatatt gttctctgag ggaactttgt
    29161 aaataatcaa tgcggatgta tgccaatatt cagcactgac tccactgtca gcgacagcag
    29221 acacatttga ttgaaatttg atgtcaatca acttaatgcc tggattttcg gcaagccagc
    29281 tatttatttg gtcgtcaatc acctcatgat gtggataatc acatgaaaaa aatacggttt
    29341 taatcatatt cccctcctgg attgtgccac cagatcatca ggtcttcctg attatctctg
    29401 atgtactgct caaatatttc aaagtggacg atagcatgtt ttaagcgttg cataccctct
    29461 ccagattttg agcaaaagct gaaaacttta aagacaggct caatcatgtc aataatttct
    29521 acgacttggc cattgaggtt ccagacgcta tcctctccca cattgaaatc aaggataaac
    29581 tcatccccta ggttgtggat aacctgcaat ttcttgccgt ccgagtagat ggctacgctg
    29641 tcagatattt ttctgatgtc catggttacc tccccattga ctctggagaa atatccaaga
    29701 tttttctatc tccaatttcc tttttttcgc catacagagt cgctaatagg tcctctattt
    29761 ttcctattaa ctcatcaggc accccatatt cagccaattc ttctgaaatt ttttcaattt
    29821 ctgtcatact taccacccac attgttcatt tagttcagcc tgagttaatg gctcgatacg
    29881 ttgataaccc ctgacttgat agttcttttt aaaatcaaat ccgagttgac ttagaccagc
    29941 cttgaaacgg tctttttcgg ctgtgtctac aaaatacacc tctaaagtca ttttttgggc
    30001 atatcgtttt aggtcatttt cagcccctct aagagcgtta ggctcatttt ggaggatttg
    30061 tccaccgtcc aagattttgc ccgtttctgg gtcaaaattt ggggtttccg ttgattttgg
    30121 agcctgttct tgctgtttgg tttgttgggc tgctaaaagt tcctgacttt ctcgctctgc
    30181 tcgttcttga gcctgtctga tttcttcctt ttgcttttca aactcataat cagctttgat
    30241 ttgtccaaag acttcagcaa gagtcaagtc tttcagctgt ctaatgtaag gtgagtcagt
    30301 catgccatac tcagcacata accctgaaat agctgacttg gctttttcaa attcttgttg
    30361 tttctgaaat tcaaatgtga ccatgtcatc aagtgacttc atagtggctt ttttaagcgt
    30421 cacgccatct gccataaaat cgctagcttt gacatactca agggcctttt catcaaagag
    30481 acgaggatcc agcatgtact cagctgattt gttggctagg tagcctttga ctgtgtcaat
    30541 tcggacagcc ttttgatgtt cttcaaactc tttgacatca ccagcaattt tggtaatgat
    30601 gtcttttaga ggctggatgg cattcttgac atacttgtca aattcatcag ctggttcaga
    30661 taagactttc ttattcctga tccgttcatc agaaacctgc ttgtctaatt ttcgtagatc
    30721 ggcaagtgtc tgcttgtcat ccttgatagt tgcagccgta accgtgtaat tttgatactt
    30781 tgctacaacc tcattgatat tctgctcaaa tttctcacgg tcaatgattt caacctgtgc
    30841 ttgtgttact tttacctgta attcttgcat gttgtcctcc taatattcaa gttcaccgtc
    30901 tagcaactcg ccctggattg gatcctcatt ttgagtaggt tcaggatctg catgatttgc
    30961 ctcttgctct tttttgaatt gatcaatctg agccatcttg cgtgctacga catcctcacg
    31021 gctctcttga ggtgtgacgt ctttgattgc gtcaaatgta tctccaccat cgatgtctgt
    31081 atacatgttc ccaagttcgt cagggaaagc ctctctaaga gtctgcacta gagctgtttt
    31141 tctgatcata gtggctggca ttgatttcca agtgctccgt ggattgccat ttctgtctgt
    31201 tttgacatac tcattaaagt caactgtgac cttatatctg tgtgaacggt ctttacgata
    31261 gacaacggcc caaccaccta ttagaatgtc ctcaggtaat ttaagagagc cctcaatctc
    31321 tatcatttct ccatttctca tgacagtaat tccagcctca aaaccatcat atccctcaca
    31381 acgttcagca cgtttcataa atgcctcttt tgagacaatc aagctgaact ctgtgccgct
    31441 attgttttga taggctacaa tgtagacctc gttagcaaat gggttaagat tgcgaccttt
    31501 acacaaggct agagcctgac ctacttgttt ttcagtcagt aggttttgtg ggtcaaaata
    31561 ctttttgatg tctgccccag tcaataaact tggatcagta gtgatgtcac gttttatctg
    31621 tgttgctaat tgattattag tcatcttgtt ttctcctatg tgttcatgtc aattctgcgt
    31681 ctagacttac tatttaagtc atctaattca tttttgtaat cttgaataag ttgcaaattc
    31741 cggtcaatga agcgttctac aacttgacct agaagttctt gtgttgtcac gcctctcaat
    31801 tcagcaagaa gtctgatata ttctttttgt ttttcagaga tctctgctct tatgaacgac
    31861 tttcctttat tggtcatctg cgtcattttt ttctccttta ggctagcaat ctcctacata
    31921 gatccattga ccagcgctga aaatccaatc agctgggtca agttcttctc gttcttcagg
    31981 cggttgcatt atatctctgt cataattaaa catgagcata caccttccca agctccagaa
    32041 ctcgtttcac atatctagcc ttggatgtta gcccaagatc cagcaattcg tttttttctt
    32101 catgattggc caaaagccag acacggtttt caatttcaat ctttgtcatc ttcctgctcc
    32161 acctcttcaa ttttcacttc gctatttaga cgtttcatgg cttcatctac cgacttgccg
    32221 tctaagacgt ccttgatcat gtggcttaca tcgtgcattg tttgagcctt cgccttgctt
    32281 ctttcagtct ctggcatcaa tccgacatct tgtagagcca gaaaggctaa actgacatcg
    32341 tgcatttctt tctgaagctg tttgattttt ttgattgttt ttagtgcttt aaacatattg
    32401 ttctcctttt ttgtcaaaat tttctttata cttgtaggca gcaagctcct gcttcaagtc
    32461 atggttttct tgctcacgca taaagcgacg tttgcgctct tcgagaaggt cattgctaac
    32521 ctcaatagca acctctctcc agtcaaggtt gactgattta ataacacctt cgagtctgag
    32581 ttttaattta gtaagtaatt tcattaagct acgccctcct cgttagattg cttgttcatg
    32641 cctaaaataa tgtcatagta cgaatgacca gcagggatga catagcctgt caaatcatca
    32701 acttgagaac catctgccat aatgtttaca attcttggtt tccattgctc tttttttctc
    32761 ttcatgttat aattacctcg aatacttttg ttgagcgcct gattgccgtc aggtgctttt
    32821 tgttgtcttc tagactgtct tactttccat cgccctgagt tctatctcat ggctgacttg
    32881 ttttaatagc ttctcacacg ctatttttgc ttctctgtac gttgtagatt cgctgatgaa
    32941 gtaatcagca agttcaatga ttttatcttc caatattgcc tccaaaaatc agcctcaaga
    33001 ccgatgtaat atcctcctaa attgctataa taatctcgac taggacctct caccgtttta
    33061 gtcaaaattc caatagaaag gaggagtttt tatgaaatcc tttaaagatt ttcgagaatc
    33121 tttaacagct gaagatatgc aagctatctc tgctaaagct aatgaagcta ctaaacagat
    33181 tgaccataca gacggattgc aactggggaa ggtcagtggt ttgacttctg taataactac
    33241 tattgagtta cttgagaagt atcatgaatg gcttcatagc taagacgctt aaattcttct
    33301 gagtctatct gaaaattgat aggctttttt tgtaaacact caagaaaact agtgtttctt
    33361 aaaagttttt caactaactc agggtcggcc tttacaaagg tggactcttt tttcccacta
    33421 tacggatatc gtcttggtct catttcctca cctcctttgt atttattttt tctaccctct
    33481 cttttattta tttagagaag taggactggt tgtcttttaa tatttattgt tatttaatac
    33541 ttgttgttag ttaatattta ttagtgccca aaatctgaca tctcactttc tgacatctca
    33601 ctttttggaa tgtcagaatt ataattcata gacgcctttt tgatagacag gtttaatctc
    33661 tgtttcataa tatcgaattg gaaatcagat atttttacat ctgaaaagaa tctgaatata
    33721 tgactccctc catttccagg aggttttttt ctgatttttc gcaaatatcc agcctcttca
    33781 aagattttga aatacttatc gattgtcttt cggttaacac cttttctttt agctatctca
    33841 tccggataga cttgccagtt tgggtgattg gccagcacca ccatcatgat gccaaccgct
    33901 gtaaaatcca tcgcaggatc gttgataaaa ctattactaa cagcggtata gtcgttagtt
    33961 ggattcctga aagataaatt ggcaatccaa atctttaaag tctgtcatac attctccttt
    34021 ctttattgtt taatttgtta aacattttct ttaaaaaaaa tctttcactt gcttattaaa
    34081 aactactgct aatttttgaa gtgttcgaat tttcactgtt gacgactgac ctgattcaat
    34141 caagtgtatt gttgttcgag aaacatttga cttctctgca agttcctctt gagacatttt
    34201 ctctttttca cgccattttc ttaaacgttc tccttgcaca ttcctacctc cttatttttc
    34261 tatttgttcc tcgcaattct gctataatgt agtcagaaag gagggaatgt tatgactgat
    34321 caccagctag aaacttcttt aatcgtcctt ggcaaagaat ttgatagaac caagaaaaac
    34381 ggaaaagaaa gttttagtgt tcatgtttct ttttttgatg gtttagatgc taatcagcat
    34441 cttcaagagt ttgcacgaca atatcccgta aggattgccc gtttgaagcc tgaccaaata
    34501 acttttctaa taaagtaata tcgtttagag ggaagggatt ggtttcaact ctatcgctaa
    34561 acgttaaaac aacttcacac ttctccagat aatgattggt aaattccact cgctcaactc
    34621 cgtcgagaaa cattccatcg acgaatacag cagggtggtt ttttcttgcc gtcaacaata
    34681 catcatgctc tgatgtattt actgatatag ttctgttaga cgccatttgt ttgacccttt
    34741 ctttagatag accgtcctag tcttttagaa atgatttcta catctgagtc gtccagtttc
    34801 aactggtcgg ctttttcatt taaacgagct tcgacaactt ggttaatttc aatccattct
    34861 cgttttgtaa actggcttct gaattttaga aattcgttta gtttttcttt cataccctcg
    34921 tcctactttc cattgccctg agttctatct catgactgac ttgaagaaat agcttctcac
    34981 acgctatttt agcttctctg tacgttgtgt tttcgctgat gaagtaatca gcaagttcaa
    35041 tgattttatc ttccaattct aactaccttt caaatgtggt ataatcaaaa taaaatgatt
    35101 ggagaaatct tatgaataat tttagtttta tagaaacact tgcgatcgct gccatacctg
    35161 cctttgtttc tggcatgtgg tcttacatcg ctgctaaagg aaacagcaag catgaaattg
    35221 ataaaattaa cattgcacac tcacaagagc ttgaaaatgt cgaaaatcaa tttaaacaag
    35281 atatggaaaa aatgcaaaag caacactcac aagaacttta ttcgctgcaa caaactcacg
    35341 aattaagatt acttgaactt gaaaaagtat ctcaactaga cactcaaacc gaccaaggct
    35401 taaagataaa tgacctaatt tttaaagcta tttcaggaga aatatctgca gatgtagcaa
    35461 taaaaaatat gagcactctt agtcatttcg cgaacaagca acaaccttcc gatcttcaaa
    35521 aacaatttgt gaaaaaatta tccaagaaaa atcacaaatg atactttttc ttgatatgct
    35581 ctatctcaga atcaaaccac attttgtggt ttttaatttt ctttttcaga tgatgcttac
    35641 cagctaagta agcaattaaa ttcgtgataa aactagcaat cattgatatg cctagtatcg
    35701 taagaaaaga ttcattcatc gttctactcc tttctctctt ttttcgctct atgagcaaca
    35761 acctgccaag gattcgaacc ttggtgatac caatcaggct acattcattt tgtccatcat
    35821 tcctacgaat gatgcatcga aacgaatgtc atcgatttcg tcttgagtga aaccagcatc
    35881 aagaaggtaa cgctcttggc actcgatttc ttccgctaaa tctgtccatc cgaaagcgaa
    35941 ttgacggcag ttagtgcaga atgcttcaag tttgctatag aggaaatttt cctcgtaagt
    36001 gccttggatt aaagtttcct ttgctactgc tttaaagatg ttgattgctt tctcgtttaa
    36061 tgtgttcatg gtgtttccct ccgctttgtt tttgttattt ccttaagctt gattatagtt
    36121 taacacgtta aacataaaat gtcaagcgtg ttaaacaaaa aatgtttact ttttttattt
    36181 aaagatgtat aatagattaa acaatatata gaaaggggtt tttgaatgaa gttaggagaa
    36241 ttactcaaat catatagaac agagcataaa ttatcgatgg atgctttttg tgaattatct
    36301 gatttaacaa aaggatatat ttctatgctt gaaaaaaatg aacatccgaa atcaaaaaaa
    36361 cccattgtcc catcttatga cacaatagaa aaaatcgcta aagggatgca aatttctaca
    36421 gatgatttaa ttaatatgct agatgatgaa caagaaattc aaatcaacgc tactccagct
    36481 gttctttcaa aatctcaaat ccaatccata tatgacgaac tagaaccgaa tggacaaaga
    36541 aaagttgtaa catacgctga aaaattacgt gacgaacaag agaaacgaaa aaaagcgaag
    36601 ataaacgaag tatcggagaa catcatcaga ctggacgact acagacagac tacttaccga
    36661 cgtgttactg gggttgtctc tgctggtagt ggttcgatac aggacgacga tttagatatg
    36721 gaggtttcgt tctatgagga tgaaatccca gacgactacg acgctatcgc ttatgtcgtc
    36781 ggcaactcta tggagccaaa aataaagaat ggtgactatc tttttataaa gaatacccaa
    36841 caggttgatt ataacactat cggcatcttc caagtagacg gcgctaacta tgttaagaaa
    36901 ctgcgtcagg gatatctgga aagcttgaat ccagattatg aggatataca cctagacgaa
    36961 agcaacgaca tccgaactat tggggaagtt gtcagtgtgt atagagagaa ataaaatgag
    37021 taaagaaaat ccatattttg aacaaaccaa acaaaactac atagaagttg aaaaactcta
    37081 taaacttggt aaagcaaaac atacatcttc taaataccga tttcttgcac cagcagttaa
    37141 aagacaatct gaacaattct tatttgaagc taagactcaa aaaagaaaat attggaaatt
    37201 cagtcgtggc tctctgatat tcgtagagtt cggtgtaaat ataggcggag aattatcaaa
    37261 taaccattgg gctattgtct tagacaaggt agatagtccc tataaaaaaa cactcacagt
    37321 aattcctcta acatctaaaa atcaaataga taccgtactc atagacgaaa tcattgcgga
    37381 atatccttct attttgcttg atgaatatat tgaaaaatta cacaaagaat tatttgccta
    37441 cctaaaatat ttagattcca ataatgcaat tactgaagct gccttatcgg atgtctacca
    37501 agcttataca gagcaatttt caaacgaaat aattcaacct aagatagtag acgatgacaa
    37561 ccttaaacgg acacaatcag aaataactga cattattgaa ttaactcaat actacaaaaa
    37621 atacattaag cgttcttatg ccaagtgtaa taaccttcaa acaatcagca aagatagaat
    37681 tttaaagaaa aatagattag atccaatcgg aaaaatgaaa gtatctgata acacattgga
    37741 caaaattaac gaaaagttaa aagaattata ccttttctaa tctcttgaca tttcttaata
    37801 attatattac aatacagcta ttaggagttt agctccataa agtttacatt tggattttag
    37861 atccataacg tgatggtagc cgtatttgat acggctactt ttctttttat ctagcaactg
    37921 tttccatttt ggaaacaact caaaaaagcc ccacgctctc ggtcggcaaa cttctgagcg
    37981 tgaggctagc aattacaaga aaaacttttc aaaagatatt accttttgag atgttttctt
    38041 gtacccattt tatcattttt taggaaattt tgaaagaggt actactatga taacaacaaa
    38101 taaagtagct atatatgtca gggtatcgac gacaaaccag gttgaggagg gatactctat
    38161 agatgagcaa aaagacaagc tctctagcta ctgcgacatt aaagactgga atgtatataa
    38221 agtatatact gatggaggtt tctcaggatc caatactgac agaccagcgc tagaaagtct
    38281 tatcaaagac gctaaaaaaa gaaaatttga cacagttcta gtctataagc tggaccgtct
    38341 tagccgtagt caaaaagaca cgcttcactt gattgaggat gtattcatca agaatgggat
    38401 tgaatttctg agcttgcagg agaactttga cacctctact ccttttggta aggctatgat
    38461 tggactcttg agcgtctttg ctcagctaga aagggagcaa atcaaggaac gcatgcaact
    38521 tggcaagcta ggacgtgcca aatctggtaa atccatgatg tgggctaaga catcctatgg
    38581 ttacgattac cacaaagaga caggcacagt gaccatcaat ccagctcagg ctctgaccat
    38641 taagtttatc tttgagagtt acctgagagg gagatctatt actaagttga gagatgatct
    38701 aaatgagaaa tacccaaagc atgtgccttg gagctatcgg gcggtcagaa ccatactcga
    38761 taaccctgtc tattgtggtt tcaatcagta taagggagaa atttatccag gtaatcatga
    38821 gccgattatt tcaaaagagg aatacgataa gactcaatct gagctaaaaa taagacaaag
    38881 aacagcagca gagaatgtca atcctagacc attccaagct aagtacattt tatccggtat
    38941 cgcccaatgt ggatattgtg gcgctccttt aaaaattatg ttaggcgtaa agaggaaaga
    39001 tgggagcagg ttaaaaaaat atgaatgcca ccaaaggcac ccacgaacgc tgagaggcgt
    39061 tactacctac aacgacaata aaaagtgtga ctcaggattt tactacaaag acaagctaga
    39121 ggcctatgtg ctaaaagaaa taagcaaact acaagatgac gctgattacc tggacaaaat
    39181 attttcagga gacaatgctg agaccataga ccgtgagagc tataagaaac aaatagagga
    39241 gctatcaaag aaactgagca gacttaacga tctatacata gatgaccgca ttacccttga
    39301 agaattacag agcaagtcag ccgaatttat aagcatgagg gggactcttg aaactgaact
    39361 agaaaacgat ccagcactca ggaagaacaa aagaaaggct gatatgagga aactgctaaa
    39421 cgctgagaaa gtcttttcaa tggactacga aaatcaaaag gtgcttgtta gaaggcttat
    39481 aaacaaggtt aaggtgacag ctgaggacat tgttatcaat tggaaaatat aaataatttt
    39541 agtaacctac at
//
LOCUS       DBEJJV010000017        39397 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.017, whole genome shotgun sequence.
ACCESSION   DBEJJV010000017 DBEJJV010000000
VERSION     DBEJJV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 39397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.017"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(68..1048)
                     /gene="dusB"
                     /locus_tag="ACL3GT_001018"
     CDS             complement(68..1048)
                     /gene="dusB"
                     /locus_tag="ACL3GT_001018"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HGR0516696.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1035..1907)
                     /gene="hslO"
                     /locus_tag="ACL3GT_001019"
     CDS             complement(1035..1907)
                     /gene="hslO"
                     /locus_tag="ACL3GT_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HGR0516697.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2072..3499
                     /locus_tag="ACL3GT_001020"
     CDS             2072..3499
                     /locus_tag="ACL3GT_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0516698.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLVAIRQLLFT"
     gene            3658..5166
                     /gene="glpK"
                     /locus_tag="ACL3GT_001021"
     CDS             3658..5166
                     /gene="glpK"
                     /locus_tag="ACL3GT_001021"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HGR0516699.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNFVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5208..7034
                     /gene="glpO"
                     /locus_tag="ACL3GT_001022"
     CDS             5208..7034
                     /gene="glpO"
                     /locus_tag="ACL3GT_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HGR0516700.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7104..7808
                     /locus_tag="ACL3GT_001023"
     CDS             7104..7808
                     /locus_tag="ACL3GT_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HGR0516701.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8105..8308
                     /locus_tag="ACL3GT_001024"
     CDS             8105..8308
                     /locus_tag="ACL3GT_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516702.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8395..9003)
                     /locus_tag="ACL3GT_001025"
     CDS             complement(8395..9003)
                     /locus_tag="ACL3GT_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516703.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            9135..9326
                     /locus_tag="ACL3GT_001026"
     CDS             9135..9326
                     /locus_tag="ACL3GT_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516704.1"
                     /translation="MLNAKIFYIFLCLIVIETTGLLLLKRGLEMGYLDTEAIILAVFS
                     FAFYNLCSFAWVCSTIKNK"
     gene            10137..11414
                     /gene="ltrA"
                     /locus_tag="ACL3GT_001027"
     CDS             10137..11414
                     /gene="ltrA"
                     /locus_tag="ACL3GT_001027"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HGR0516705.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGISTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVVSEAAAKRMMYSVSRFIEKRLGLKANMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            11870..13048
                     /locus_tag="ACL3GT_001028"
     CDS             11870..13048
                     /locus_tag="ACL3GT_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ryptide export MFS transporter"
                     /protein_id="HGR0516706.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13362..13493
                     /locus_tag="ACL3GT_001029"
     CDS             13362..13493
                     /locus_tag="ACL3GT_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HGR0516707.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13514..15064
                     /gene="dltA"
                     /locus_tag="ACL3GT_001030"
     CDS             13514..15064
                     /gene="dltA"
                     /locus_tag="ACL3GT_001030"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HGR0516708.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNAHIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFENLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15061..16305
                     /gene="dltB"
                     /locus_tag="ACL3GT_001031"
     CDS             15061..16305
                     /gene="dltB"
                     /locus_tag="ACL3GT_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HGR0516709.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQTIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16319..16558
                     /gene="dltC"
                     /locus_tag="ACL3GT_001032"
     CDS             16319..16558
                     /gene="dltC"
                     /locus_tag="ACL3GT_001032"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HGR0516710.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16551..17819
                     /gene="dltD"
                     /locus_tag="ACL3GT_001033"
     CDS             16551..17819
                     /gene="dltD"
                     /locus_tag="ACL3GT_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HGR0516711.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLQQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            17974..18414
                     /gene="adcR"
                     /locus_tag="ACL3GT_001034"
     CDS             17974..18414
                     /gene="adcR"
                     /locus_tag="ACL3GT_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HGR0516712.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18414..19118
                     /locus_tag="ACL3GT_001035"
     CDS             18414..19118
                     /locus_tag="ACL3GT_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HGR0516713.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19111..19917
                     /locus_tag="ACL3GT_001036"
     CDS             19111..19917
                     /locus_tag="ACL3GT_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HGR0516714.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAVVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            19927..21432
                     /gene="adcA"
                     /locus_tag="ACL3GT_001037"
     CDS             19927..21432
                     /gene="adcA"
                     /locus_tag="ACL3GT_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HGR0516715.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYTEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22603..23376)
                     /locus_tag="ACL3GT_001038"
     CDS             complement(22603..23376)
                     /locus_tag="ACL3GT_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0516716.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSTRGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            23552..24955
                     /locus_tag="ACL3GT_001039"
     CDS             23552..24955
                     /locus_tag="ACL3GT_001039"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase family protein"
                     /protein_id="HGR0516717.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGEITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            25070..25708
                     /locus_tag="ACL3GT_001040"
     CDS             25070..25708
                     /locus_tag="ACL3GT_001040"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HGR0516718.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            25720..26160
                     /locus_tag="ACL3GT_001041"
     CDS             25720..26160
                     /locus_tag="ACL3GT_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HGR0516719.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26153..26584
                     /locus_tag="ACL3GT_001042"
     CDS             26153..26584
                     /locus_tag="ACL3GT_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0516720.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26575..27045
                     /locus_tag="ACL3GT_001043"
     CDS             26575..27045
                     /locus_tag="ACL3GT_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0516721.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27070..27843
                     /locus_tag="ACL3GT_001044"
     CDS             27070..27843
                     /locus_tag="ACL3GT_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HGR0516722.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            27840..28640
                     /locus_tag="ACL3GT_001045"
     CDS             27840..28640
                     /locus_tag="ACL3GT_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0516723.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            28699..30993
                     /locus_tag="ACL3GT_001046"
     CDS             28699..30993
                     /locus_tag="ACL3GT_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HGR0516724.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELCIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31003..34119
                     /locus_tag="ACL3GT_001047"
     CDS             31003..34119
                     /locus_tag="ACL3GT_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 98 C-terminal
                     domain-containing protein"
                     /protein_id="HGR0516725.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34176..35942
                     /locus_tag="ACL3GT_001048"
     CDS             34176..35942
                     /locus_tag="ACL3GT_001048"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008736 - L-fucose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0019317 - fucose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HGR0516726.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            36088..37239
                     /locus_tag="ACL3GT_001049"
     CDS             36088..37239
                     /locus_tag="ACL3GT_001049"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HGR0516727.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37384..38268
                     /locus_tag="ACL3GT_001050"
     CDS             37384..38268
                     /locus_tag="ACL3GT_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0516728.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(38305..38463)
                     /locus_tag="ACL3GT_001051"
     CDS             complement(38305..38463)
                     /locus_tag="ACL3GT_001051"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516729.1"
                     /translation="MKIKEQTRKLATGCSKHRFEVVDKTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            38667..38918
                     /locus_tag="ACL3GT_001052"
     CDS             38667..38918
                     /locus_tag="ACL3GT_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HGR0516730.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            38906..39196
                     /locus_tag="ACL3GT_001053"
     CDS             38906..39196
                     /locus_tag="ACL3GT_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0516731.1"
                     /translation="MGALGYYEGFVPYVSNQYQNQAEEEYKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT        12178 a         6785 c         8549 g        11885 t
ORIGIN      
        1 tttttttgat gaggaaagaa tggcggcact caagagactc tttaagagag ttacgggttt
       61 taaactatta agccttctcc aattgcaaga gagcttcaat ctctgccagg gtgctagctt
      121 gcgaaatggc tccacggagt ttggcagcgc cagatgttcc acggaggtag tgaggagcga
      181 ggccacggaa ttcacgaact gcgacgtttt ctcctttgag gttaatcaat cgtttcaagt
      241 gttcgtaggc gatcttcatc ttgtcttcaa aggtcaaatc aggtaggatt tctcctgttt
      301 caaagtaatg gttgatttgg ttgaagaggt aaggatttcc catggcagct cggccaatca
      361 tgactgcgtc agcaccaact tcttcgatgc gttgcttggc ttcttggaca gtacggatat
      421 caccgttggc gatgaatgga atcttggtta gagcttgggc aaccttgtac agggtctcaa
      481 ggtctgcgtg gccagtatac atttgttcac gggtacggcc atgcatggcg agggcagaaa
      541 cacctgcagc ctcagcagcg agggcatttt ctactgccag agatgggtcc gcccagccgg
      601 tacgcatttt gacagtaagt gggatatcaa ggacagactg gaccttgttg atgatagagt
      661 agatcttgtc aggatccttg agccacatag ctccagcttc gttcttcacg attttgttga
      721 cagggcagcc catgttgata tcgacgatat cggtcttggt gttttcttgg atgaattctg
      781 ctgcgcgtgc taggctgtct tcatcgctac caaaaagttg gatagagaca gggttttcgc
      841 cctcatcgat atgaagcatg tgcagggttt tttcgttgtt gtattggatt cccttgtcag
      901 agaccatttc cattacaacg agtccagctc cgagctcttt tgcgatggta cgaaaggctg
      961 agttggtcac gccagccata ggcgctaaaa cggtacgatt gggaatctca acattgccaa
     1021 tcataaaagg tgtattaaga tttgtcacga atgagttcct ccaggtcctt ttcatcaaag
     1081 ttgtaagtag tttggcagaa ttgacaagtg atttctaccc cgtggtcttc ctctttcatt
     1141 tcctgtaagt ctgagcttgg aaggctggca agagcgttca taaagcgttc atggctacag
     1201 tcacattgga aacggatttc ttcttcagaa agacgcttgt aggcttcgtc cccgtagata
     1261 gccttgagga gggcttcgat atggtcgtcg ctttcgagaa gagtagagat agctggcatt
     1321 tcttggatgc gtttttcaaa gcgagcaatc tcttctttct tggctcctgg caagacttga
     1381 actaggaaac cacctgcaac cttgaccttg tcttcctcgt ccaaaaggac attgaggccg
     1441 accgctgaag gcgtttgttg gctttcagta aggtaaaagg caaggtcttc accgatttct
     1501 ccagagatga ggggagttat agagttgtaa ggatttccag caccgtagtc tgtgataacg
     1561 aggaattgac catttccaac aaaaggtccg actaggactt caccagtcgc agtctttttg
     1621 atgtcaacac caggattttg aacatagcct ttgacgttcc ccttggtatc agcgacggtg
     1681 ataatagcac ctagagagct agagcccaac accttaactg taagtttggt atttcctttt
     1741 tcattggctg cgagaatctg gctggcgata agagttcgac caagcgctac agttgagcta
     1801 gcttgggttt gatgtttttc ttgagcagtg cggacggttt ccgtgctatc aaggacaaaa
     1861 gcacgaaagg ctccgctttc tgatatagtt ttaataattt tatccatagc tactatttta
     1921 gcataaaaat gcccaaaggg ggagccgtgt gtttactgat tttcaggata atggaccagg
     1981 aaatcagcat gaaaataaaa agagaaacag attattttag catttgtaag atttatgcta
     2041 tgcttaaggt agaaaatgaa aggggtaaca aatgtattta ggagatttga tggagaaagc
     2101 cgagtgtggt caattttcaa tcctttcctt tctattacaa gagtctcaga cgaccgtcaa
     2161 ggctgtaatg gaagaaacag gattttcaaa agcaacccta accaaatatg tcaccctgct
     2221 caatgacaag gctttggata gtggcttaga gctggctatt cactcagaag atgaaaatct
     2281 gcgtctgtct atcggtgcag ctaccaaggg gagagatatt cggagcttgt ttttggagag
     2341 tgctgttaaa taccagattt tggtttatct tctctaccac caacagtttt tagcccatca
     2401 gctggctcaa gaattggtga ttagcgaggc tacgcttggt cgtcacttgg ctggtttaaa
     2461 tcagattttg tcagaatttg atttatccat ccaaaatgga cgttggcgag gtccagagca
     2521 tcagattcgc tatttctatt tctgtctttt ccgaaaggtc tggtcgagtc aggaatggga
     2581 aggtcacatg cagaaaccag agagaaaaca ggagattgcc aatttagagg aaatctgcgg
     2641 tgcaagtttg tctgtggggc agaaattgga cttggttctc tgggctcaca tcagtcaaca
     2701 acgtcttcgg gtcaatgctt gtcagtttca agtcatagaa gagaaaatgc gagggtattt
     2761 tgacaatatt ttctaccttc gtttgctgag aaaggttccg tccttttttg ctgggcaaca
     2821 tattccacta ggagttgagg atggtgagat gatgatattc ttctcttttc tcctatctca
     2881 tcgcattctt cctcttcata ctatggagta tattcttggt tttggagggc agttggcaga
     2941 tttactgacg caattgattc aagaaatgaa gaaggaggaa ctattggggg attatacaga
     3001 ggaccatgtc acctatgaac tcagtcagct ttgtgctcaa gtctatctct ataagggcta
     3061 tattttacag gatcgctaca agtaccagtt agagaatcgt catccatatt tactgatgga
     3121 acatgatttt aaagagacag cagaggagat ttttcatgct ctacctgctt ttcaacaggg
     3181 gacagattta gataagaaga ttctctggga atggctccag ttaatcgaat atatggctga
     3241 aaacggtggc cagcatatgc ggattggtct ggatttgaca tctggttttc ttgtcttttc
     3301 aaggatggca gccattttga aacggtattt ggaatacaat cgttttatta ccattgaagc
     3361 ctatgaccct agtcggcatt atgatttgct ggttaccaat aacccgattc ataagaagga
     3421 acagacacca gtctattatt taaaaaatga cttggatatg gaggatttgg tagcgattcg
     3481 ccagttatta ttcacttaaa aggcttggtt aatccaggtc ttttttgtga aattcacaca
     3541 atctcctcac atttttttaa aaattaaaaa aagttgataa acaagaaagc gctttatttt
     3601 gtatactagt aagtgtaaag aggaaacacc tcaagatctt tatcaggagg acagtacatg
     3661 tcacaagaaa aatacatcat ggccattgac cagggaacta caagttctcg tgccatcatt
     3721 ttcaacaaaa aaggggaaaa ggttagctcg agtcaaaaag agtttaccca gattttccct
     3781 caggcaggtt gggttgagca caatgccaat gaaatttgga actttgttca gtcagttatt
     3841 gcgggtgctt tcatcgaaag tggtgtcaag ccaaatcaaa tcgaggcaat cgggattacc
     3901 aaccaacgtg aaacaacggt tgtctgggat aagaaaacag gacttcctat ctacaatgct
     3961 atcgtttggc agtcacgcca gacagcacct ttggctgagc aactaaaaag ccaaggttat
     4021 gtggaaaaat tccatgaaaa gactggtttg attattgatg cttacttctc tgctaccaag
     4081 gttcgttgga ttttggatca tgtagaaggt gctcaagagc gagcagaaaa aggggaattg
     4141 ctctttggta ctatcgatac ttggttggtt tggaaattga ctgacggtgc ggctcacgtg
     4201 actgactact caaatgcagc tcgtaccatg ctttataaca ttaaagaact caaatgggat
     4261 gatgagattt tggaaatcct taacattccg aaggctatac ttccagaagt tcgttctaac
     4321 tccgaaatct acggcaagac agctccattc catttctacg gtggagaggt gccaatctca
     4381 ggtatggctg gggaccaaca agcagccctc tttggacagt tggcttttga gccaggtatg
     4441 gttaagaata cttatggaac aggctctttc atcatcatga atactgggga agagatgcag
     4501 ttgtctgaaa acaacctctt gacaaccatt ggttacggaa tcaacggtaa ggtttattat
     4561 gccttggaag gttctatctt catcgcagga agtgctattc agtggcttcg tgacggtctt
     4621 cgcatggttg aaaattcacc agaatctgaa aaatacgctc gtgattctca caacaacgat
     4681 gaagtttatg tcgttccagc ctttacaggt ctaggcgctc catactggaa ccaaaatgct
     4741 cgtggttccg tctttggttt gactcgtgga acaagcaaag aagactttat caaggcgact
     4801 ttgcaatcta ttgcttatca agtgcgtgat atcatcgaca ccatgcaagt ggatactcag
     4861 accgccattc aagtactgaa ggtggatggt ggtgcagcca tgaacaactt cctcatgcag
     4921 ttccaggcgg atattttagg cattgacatt gcacgtgcta aaaacttgga aacaacagct
     4981 ctaggagcgg ccttcctagc aggtttgtca gtagggtact ggaaagactt ggacgagttg
     5041 aaactcttga acgagacagg agaactcttt gagccatcta tgaacgaatc tcgcaaggaa
     5101 caactctaca agggctggaa gaaggctgtg aaagcaactc aagtctttgc ggaagtagac
     5161 gactaatact ggcagaataa agcgatttat ttagaaagtg tgtaaatatg gaattttcaa
     5221 aaaaaacacg tgaattgtca attaaaaaaa tgcaggaacg caccctggac ctcttgatta
     5281 tcggtggagg aatcacagga gctggtgtag ccttgcaggc ggcagctagc ggtcttgaga
     5341 ctggtttgat tgaaatgcaa gactttgcag aaggaacatc tagtcgttca acaaaattgg
     5401 ttcacggagg tcttcgctac ctcaaacaat tcgacgtaga agtggtctca gatacggttt
     5461 ctgaacgtgc agtggttcaa caaatcgctc cacacattcc aaaaccagat ccaatgctct
     5521 taccagttta cgatgaagat ggagcaacct ttagcctctt ccgtcttaaa gtagccatgg
     5581 acttgtacga cctcttggca ggtgttagca acacaccaac tgcgaacaag gttttgagca
     5641 agaaagaagt cttggaacgc cagccaaact tgaagaagga aggcttggta ggaggtggag
     5701 tgtatcttga cttccgtaac aacgatgcgc gtctcgtgat tgaaaacatc aaacgtgcca
     5761 accaagacgg tgccctcatt gccaaccacg tgaaggcaga aggcttcctc tttgacgaaa
     5821 gtggcaagat tacaggtgtt gtagctcgtg atctcttgac agatcaagta tttgaaatca
     5881 aggcccgtct ggttattaat acaacaggtc cttggagtga taaagtacgt aatttgtcta
     5941 ataagggaac gcaattctca caaatgcgcc caactaaggg agttcacttg gtagtggatt
     6001 caagcaaaat caaggtttca cagccagttt acttcgacac aggtttgggt gacggtcgta
     6061 tggtctttgt tctcccacgt gaaaacaaga cttactttgg tacaactgat acagactaca
     6121 caggtgattt ggagcatcca aaagtaactc aagaagatgt agattatcta cttggcattg
     6181 tcaacaaccg ctttccagaa tccaacatca ccattgatga tatcgaaagc agctgggcag
     6241 gtcttcgtcc attgattgca gggaacagtg cctctgacta taatggtgga aataacggta
     6301 ccatcagtga tgaaagcttt gacaacttga ttgcgactgt tgaatcttat ctctccaaag
     6361 aaaaaacacg tgaagatgtt gagtctgctg tcagcaagct tgaaagtagc acatctgaga
     6421 aatatttgga tccatctgca gtttctcgtg ggtctagctt ggaccgtgat gacaatggtc
     6481 ttttgactct tgctggcggt aaaatcacag actaccgtaa gatggctgaa ggagctatgg
     6541 agcgcgtggt tgacatcctc aaagcagaat ttgaccgtag ctttaaattg atcaattcta
     6601 aaacttaccc tgtttcaggt ggagaattga acccagcaaa tgtggattca gaaatcgaag
     6661 cctttgcgca acttggagta tcacgtggtt tggatagcaa ggaagctcac tatctggcaa
     6721 atctttacgg ttcaaatgca ccgaaggtct ttgcacttgc tcacagcttg gaacaagcgc
     6781 caggactcag cttggcagat accttgtccc ttcactatgc aatgcgcaac gagttggctc
     6841 ttagcccagt tgacttcctt cttcgtcgta ccaaccatat gctctttatg cgtgatagct
     6901 tggatagcat cgttgagcca gttttggatg aaatgggacg attctatgac tggacagaag
     6961 aagaaaaagc aacttaccgt gctgatgtcg aagcagctct cgctaacaac gatttagcag
     7021 aattaaaaaa ttaagaaaaa ataaaagagg tggagggcag cattccttgt cgcccgtccc
     7081 ttctttttaa tggagacaga aagatgatga atgaattatt tggagaattt ctagggactt
     7141 taatcctgat tcttctagga aatggtgttg ttgcaggtgt ggttcttcct aaaaccaaga
     7201 gcaatagctc aggttggatt gtgattacta tgggttgggg gattgcagtt gcggttgcag
     7261 tctttgtatc tggcaagctc agtccagctc atttaaatcc agctgtgaca gttggtgtag
     7321 ctttaaaagg tgacttgcct tgggcttccg ttttgcctta tatcttagcc cagttcgcag
     7381 gggccatgtt gggtcagatt ttggtttggt tgcaattcaa acctcactat gaggcagaag
     7441 aaaatgcagg caatatcctg gcaaccttca gtactggacc agccatcaag gatactgtat
     7501 caaacttgat tagcgaaatc cttggaacct ttgttttggt gttgacaatc tttgctttgg
     7561 gtctttacga ttttcaggca ggtatcggaa cctttgcagt gggaactttg attgtcggta
     7621 tcggtctatc actaggtggg acaacaggtt atgccttgaa cccagctcgt gaccttggac
     7681 ctcgtatcat gcacagcatc ttgccaattc caaacaaggg agacggagac tggtcttacg
     7741 cttggattcc tgttgtaggc cctgttatcg gagcagcctt ggcagtgctt gtattctcac
     7801 ttttctagtt tatactcttc gaaaatcaaa ttcaaaccac gtcagcgtcg ccttaccgta
     7861 ctcaagtaca gcttgcggct agcttcctag tttgctcttt gattttcatt gagtattaga
     7921 aaacaattat gttgatagag cttgggcaag agcccaattt cagcaaaaaa tgaagtaaat
     7981 cttctcataa taaaacgcat catatcaagc acgaaaattc cacgaggtca actacagtca
     8041 gaaagctgaa caacaagcca aaacgcccaa aaaaggcggc aaaaagcaag cacctgcaag
     8101 caacgtgccg aaatggtcaa atcctgatta tgtcaacgaa ttagacccaa aaatcgttga
     8161 tatgctagta gaatttcaca agtcacaagg cactttggaa actcccgagg cgcaagcaga
     8221 aatcgcccaa aaacgtgaag aaatcgagca aaggagagct gagcttgagg ataaaaaaca
     8281 agagcttttg aaccgcttga acaaatagag tttcgcaagt attatgctta caaattactt
     8341 gagcaattaa ctaaaatata aaccctgcct agatataaag gcagggttta tattttagaa
     8401 attcacgtag gttgttacgg tttttacata cccagtatag tttgagtttc tatagtattc
     8461 agtgataaac ttccattttc tttgagcaac atggatataa gtacttgtta tgtagtatgg
     8521 atatgggctt tgtgaatcca agtaagactg ataagcttgt ataccaaaat atgctccacc
     8581 aattattgca ccccatggac cccccaataa agcacctatc ctaccaatca tataactgat
     8641 tccagcacca gtcatgaagt tagcgaatgt gttagcttgt ttattcccat gtattgtgtt
     8701 gacgtaattc caaacattag gatcgtatga tctaaaagat atatttaggt cgatttcatt
     8761 cttttgataa gccatataaa atgccccatt gatatagacg ccgtcagcac gtcgttcaat
     8821 agtgtctaca cttccatctg gattgacaac ctcaagaact tcatcgctta aaatatttac
     8881 ttgcgtatct ccgaaccgca ctgatgagcc attctcaaac tgagcctcac cagatacaac
     8941 tttagagttt gccgataagc tatcatcagc aaaaacaaca agcgacgggg aaatgctaga
     9001 catacagaaa acagacataa ctagcaaaca catgcattta aacatcttag acataacgga
     9061 aactcttttg tatttttgat ttttttcaac ttttattata caataaaacc aaataaaaag
     9121 aaagcggtaa caatatgctt aatgcgaaaa ttttttatat atttttatgt ttgatcgtta
     9181 tcgaaactac aggcttgttg ttgttgaaaa gaggtctcga aatgggttat ttagacacag
     9241 aagctattat cctcgcagtt ttttcatttg ctttttacaa cctatgttca ttcgcttggg
     9301 tctgctctac aataaaaaat aaatagacgt attttcaaaa aaaaaaaaat gaatatttat
     9361 attagcaaaa tgacgattta aatcgtcgtt tttttgtagt acgacgggca tgtcgtatat
     9421 ctgaggtgta agtcctcggt gggcacctgc taccggtgaa cccaatagcg attcccaagc
     9481 ctgactatcg tgaggtagcg gattaaaacg gtctggggat agaccgtttt aagtctgacg
     9541 caggaaataa gaatcgtcag aggaagggat agcgaaatcg tggctctacg aacaggaacg
     9601 tgatagtaag gcgtatatag cggataagga ggcttcaaac tctaaagtcc aaaaaggtag
     9661 tcgtaaccta tatgtgtaaa tcacgagagt aattgaattc ggactaaggt ttgtgtgaaa
     9721 aagataaatc tttctagagt ctaaagactc tgcgtcagat ttcctatttt cactgtaacc
     9781 ttttaacgtc ctcatatctt gtataaacga ggaaagatgt acgacttatc ccgtgaggtt
     9841 tcatgagcgc tgaaagcgta gtaacaacga atcatgagaa gtcagccgag cccatagtag
     9901 tgaggaaact tctgtagtgg aagtggagcg aaggggtgaa tactcaaaca gtctggggag
     9961 agactgtttg aggtctgtcg ctagaaagag aaaacgacag atcgaagtaa tcctacttca
    10021 cttgtgtctg taaaatgagt ggtctgatag aactggactt tgacacgtaa tgactagatg
    10081 aaggttcacc aatataagat gtccctcagg caccaaaaca agaaaggaat acgcacatgt
    10141 caaaactgct agataagata ttatcacgcg aaaatatgct ggaagcctac aatcaagtaa
    10201 aatccaataa aggctcagct gggattgatg gaatgactat cgaagagatg gataattatc
    10261 tcagacaaaa ctggcgcttg actaaggaac tgataaaaca gagaaaatat aagcctcaac
    10321 cagttcttaa agttgagata cctaaaccag acggaggcat ccgtcaacta ggaatctcaa
    10381 cagttatgga tagaatgatt caacaggcca ttgtccaagt catgagcccc atttgtgaac
    10441 cccatttctc agatacgagt tatggtttca gaccaaatag gtcatgtgaa aaagccatca
    10501 tgaagctctt agaatactta aatgacggct atgagtggat agtggatata gacctagaga
    10561 aatttttcga tacagttcct caagatagat tgatgtcctt agtacataac attatcgaag
    10621 acggagatac ggaatccttg attcgtaagt atcttcattc aggtgttatc attaatggtc
    10681 aacgttataa aacactagtt ggtacaccac agggaggaaa tttatctcct ctcttatcca
    10741 atatcatgct taatgaattg gacaaggaat tagaaaagag gggacttcga tttgtgcgct
    10801 acgcagatga ttgtgtgatt acggtcgtaa gcgaggcagc cgctaagcgt atgatgtatt
    10861 cagtcagtcg ttttattgaa aaacggctag gtttgaaagc aaacatgacc aagactaaga
    10921 ttaccagacc aagagagttg aaatatctag gttttgggtt ctggaaatca tcagatggtt
    10981 ggaaaagtcg tccacatcaa gatagtgttc ggagatttaa gcttaaattg aagaaactaa
    11041 cacagaggaa atggagtata gacctaacaa gacgtattga gcaactgaat ttgtctattc
    11101 gaggatggat aaactatttc tcattgggaa atatgaaaag tatagtcgcc agcatagatg
    11161 agcgcttgcg tactcgccta cgagtgatta tctggaagca atggaagaag aaatcgagac
    11221 gattatgggg attgcttaag ttaggggttc ctaaatggat agcagataag gtatctggct
    11281 ggggcgacca ttatcaatta gtagctcaga agtcggtact taaacgtgct atatcaaaac
    11341 cagtcctgga aaaacgtgga ctggtttcgt gtttggatta ttaccttgaa cgacatgcgt
    11401 taaaagttag ttgaaccgct gtatgccgaa cggcacgtac ggtggtgtga gaggggctag
    11461 agattatccc ctactcgatt aactcccctg aaatttattt taattatgca aatttcacgt
    11521 atttttgatg ctgagacgac gatcctggga acttttcaga tatttttttg actatctaaa
    11581 tctatcatta gaaaagctta gagcgccaaa ggatttgagc gtttttctga tttttaagac
    11641 tttttccagt ctctttttcg attgaagatg taattattct actaactaac taacttctta
    11701 gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata aaggcaatag
    11761 tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat gctaaaatat
    11821 taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca tgtctaattc
    11881 atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt tctttagagt
    11941 aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat cactagttcc
    12001 tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg ttactaaaag
    12061 gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat tattggcgat
    12121 actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct atctatttgt
    12181 tgttgcaatt tccatactag atggttttgc agcacctgtt tcctatgcta ttgtgccacg
    12241 ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg aagctgttca
    12301 attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt tacctaccac
    12361 gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc ttcctaacgc
    12421 tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag gttggaagtt
    12481 agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg aaattttttc
    12541 aaatacgatt tgggtttctt ccattatact tgtttttgta acggagttat taaataaaac
    12601 ggaaagttac tggggatatt ctaatacagc atactctatt ggtattataa ttagtggctt
    12661 aattgctttt aggctatctg aaaagttcct tgctgctaaa tgggaaagta ttctttttcc
    12721 tcttgtagct atggcaatag tgacactgac tattctatat tttccaaacg cacagatgtt
    12781 tttattattt tcagctttag ttggtatgtt atcgcaacta aaagaagttc ctgaaagtgt
    12841 atttcttcag gaaacagtag aggaaaatca tttagttaat gtctattccg ttcttgaagt
    12901 gatttctaca ttagcatttt cagtatttgt tttgctaatg agctatatta ctgagagttt
    12961 tggtattagc atcagttttt ggctatcagc catttgtctg atgatagaag ctattttaat
    13021 ttatatcaga cgagattatt ttaaatgaga gagtggttaa aaagtcttta aaaatcagaa
    13081 aagcgcatag tatcaggtgt tgaaaaaact tgatattgtg tgttttatta tgggaagatt
    13141 tacttcattg tctcctgaaa tggagttttg aagcaggatc actctatttg aaaatataca
    13201 tagaaaaact gtataatcct taaaataagc tgaaatctat tggaaacata cggtaaacaa
    13261 ttgaaaagat actatataaa gtggtacaat ggtagaaaaa taagctagta agaatcactc
    13321 ttattttagc gaaaaattac agaaatgaat ggtttttctt gatgaaacag agaaaagaat
    13381 tgtacctctt tcttggtcgg acagccttgt attttcttat ctttctaggg ctgctttact
    13441 tctttagcta tcttggtcag ggtcaaggaa gctttatcta taatgaattt taacttgaag
    13501 gagaatccct attgtgtcaa ataaaccaat agcagatatg attgaaacca ttgagcattt
    13561 tgctcagaca cagcctagct atcctgtcta taatgttttg gggcaggaac acacttatgg
    13621 cgatttaaag gctgattcgg atagtttggc tgcagtcatt gaccaactag gcttgcctga
    13681 gaagtctcct gtggttgttt ttggtggcca agaatatgaa atgttggcaa cctttgtagc
    13741 gctgactaag tcaggtcatg cctacattcc aattgatagc cattcggcct tggagcgagt
    13801 ttcagctatt ttagaagtag cagagccaag cttgattatt gccatttcag cctttccctt
    13861 ggagcaggtt tctacaccaa tgataaatct agctcaggtt caagaagcct ttgcccaagg
    13921 gaataactat gaaatcacgc atccagtcaa gggagatgat aattactaca ttatctttac
    13981 ttctggtacg actggtaagc ctaagggagt gcagatttca catgataatc tcctcagctt
    14041 tacaaactgg atgattacgg ataaggaatt tgcgacaccg agtcgtccgc aaatgctggc
    14101 acagccacct tattcttttg acttgtctgt catgtattgg gcaccgacct tggcacttgg
    14161 tggtacgctt ttcactcttc cttcagtcat cactcaggac tttaagcaac tctttgcggc
    14221 tatcttttca ttgccaatcg ctatctggac atcaacacca tcctttgcag atatggccat
    14281 gttgtctgaa tacttcaaca gtgagaaaat gcctggaatc actcatttct actttgatgg
    14341 tgaagaattg acggtcaaaa cagctcaaaa actgcgcgag cgtttcccaa atgcccatat
    14401 catcaatgct tacggcccaa cagaagcgac agtagctctg tcagcagttg ccgtgacaga
    14461 cgagatgtta gcgactctca aacgcctacc aatcggctat accaaggctg attctccaac
    14521 ctttatcatt gacgaggaag gaaataaact gccaaatggt gagcagggag aaatcattgt
    14581 ttctgggcca gctgtttcaa aaggttatat gaacaatcct gaaaaaacag cagaagcctt
    14641 ctttgagttt gaaaatctgc cagcctatca cacaggcgat gtgggaacca tgacagatga
    14701 gggcttgctt ctctacggcg gacgcatgga cttccagatt aagttcaacg gttaccgcat
    14761 tgagttagaa gatgtctctc aaaacctcaa caagtctcgc tttatcgaat ctgctgtcgc
    14821 agtaccgcgc tataacaagg accacaaggt acaaaatcta ttggcttatg tcatcttaaa
    14881 agacggtgtt cgtgagcagt ttgagcgaga tatcgatatt accaaggcca tcaaggaaga
    14941 cctgacagac atcatgatgt cctacatgat gccatctaaa ttcctttacc gagacagttt
    15001 gccactaact ccaaatggaa agattgacat caaaggattg attaacgagg tgaataagag
    15061 atgatggagt tttttcaaca gcttcctcat ttagagccat atggtaatcc tcagtatttt
    15121 gtttatgtga ttgctgcaac cttgcccatc tttataggcc tctttttcaa gaaacgcttt
    15181 gcctggtatg aagtgttggt aagtctcttc tttattgtca ccatgttggt gggtggaaag
    15241 accaatcaac tagctgcctt gggtatttac ctttgctggg aaatattgct cctgcttttc
    15301 tacaagcatt atcgaaaaag caaggatggc aagtgggtct tctacttagt tagttttctg
    15361 tccctacttc cgattatctt tgtcaaggtg caaccagcta tcaatggaac gcagtctttg
    15421 cttgggttct tgggaatttc ttacctgacc tttcgttcgg ttgggattat catcgagctg
    15481 agagatggag tgattaagga ttttaccctc tgggaattcc tccgtttcct tctcttcatg
    15541 ccaactttct cgagtggtcc aatcgatcgc tttaagcgat ttaatgaaaa ttatcagacc
    15601 attcctgagc gagatgagtt gatggatatg ctggatgaat ctgtccgcta tatcatgcgg
    15661 ggctttttgt ataagtttat cctagctcat gttttaggag agaccttact acctcctctg
    15721 aagaatttag ccttgcagtc aggtggcttc tttaatctct atgccttggc agttatgtat
    15781 acttttggtc tggagctctt ctttgacttt gcaggttatt ctatgtttgc tttggccatc
    15841 tcaaacttga tgggaatccg tagccctatc aactttaaca agcccttttt atcaagggat
    15901 ttaaaggagt tttggaatcg ctggcatatg agtctgtcct tctggttccg tgactttgtc
    15961 tttatgcgaa tggtgatggt gttaaccaga aagaaagtct ttaaaaatcg taatgtaacc
    16021 tcaagcatgg cctacattgt aaatatgctg attatgggat tttggcatgg cgtgacctgg
    16081 tactatatcg cctatggact ctttcatgga ctaggtttgg tcatcaatga tgcctgggtt
    16141 cgcaagaaaa aaacgctcaa taaggaacgg aaaaaagcag ggaaggctgc cctacctgag
    16201 aatcgctgga ttcagttgct tggcatggtt gtcactttcc atgttgtcat gttgtcattc
    16261 ttaatctttt ctggattctt gaataatcta tggtttaaaa aataaaagga aataaaatat
    16321 ggatatcaaa tcagaagtta tcgaaattat tgatgagttg tttatggaag atgtttctga
    16381 catgatggat gaagatcttt ttgatgcagg tgtcttggat agtatgggaa cggttgagtt
    16441 gattgtggag attgagaacc gttttgacat tcgtgtccct gtaacagagt ttggtcgtga
    16501 cgactggaat acagctaata aaattatagc tggtattgtg gagctacaaa atgcttaaac
    16561 gcttatggat gatcttcgga ccggtcttga tcgctggttt gttggttttt ctgctcattt
    16621 tcttttatcc tactgagatg catcataatc taggagctga aaagcgttca gcagtggcta
    16681 ctactatcga tagttttaag gagcgaagtc aaaaagtcag agcactatct gatccaaatg
    16741 tgcgttttgt tcccttcttt ggctctagtg aatggcttcg ttttgacggt gctcatcctg
    16801 cggtattagc tgagaaatac aatcgttcct accgtcctta tcttttagga caggggggag
    16861 ctgcatcgct taaccaatat tttggaatgc aacagatgtt acaacagctg gagaataaac
    16921 aagttgtgta tgttatctca cctcagtggt tcagtaaaaa tggctatgat ccagcagcct
    16981 tccagcagta ttttaatgga gaccagttga ctagttttct gaaacatcaa tctggggatc
    17041 aggctagtca atatgcagcg actcgcttac tgcaacagtt cccaaacgta gctatgaagg
    17101 acctggttca gaagttggca agtaaagaag aattgtcgac agcagacaat gaaatgattg
    17161 aattattggc tcgttttaat gaacgccagg cctccttttt tggtcagttt tcggttagag
    17221 gctatgttaa ctacgataag catgtagcta agtatttaaa aatcttgcca gaccagtttt
    17281 cttatcaagc aatagaagat gttgtcaaag cagatgctga aaaaaatact tccaataatg
    17341 agatgggaat ggaaaattat ttctataatg agcagatcaa gaaggatttg aagaaattaa
    17401 aggattctca gaaaagcttt acctatctca agtcgccaga gtataatgac ttgcagttgg
    17461 ttttaacaca gttttctaaa tctaaggtaa acccgatttt tatcattcca cctgttaata
    17521 aaaaatggat ggactatgct ggtctacgag aggatatgta ccaacaaacg gtgcagaaga
    17581 ttcgctacca gttagaaagt caaggtttta ccaatatagc agatttttct aaggacggcg
    17641 gggagccttt ctttatgaag gacaccattc accttggttg gttgggttgg ttggcttttg
    17701 acaaggcagt tgatcctttc ctatccaatc ccacaccagc tccgacttac catctgaatg
    17761 agcgcttttt cagcaaagat tgggcgactt atgatggaga tgtcaaagaa tttcaataga
    17821 taatataata tagaagagtt caagaatgaa actagttttc acgttttttc ttgactcttt
    17881 ttttgcttgt gatataatta actggtaaac aaaatgtcaa agaatagtat ttttctctta
    17941 aaaaagagaa gtctaaaagg aaaggagtca gatatgagac agctagcaaa ggatatcaat
    18001 gcttttttga atgaggtgat tttgcaggcg gaaaatcagc atgaaatcct aataggtcat
    18061 tgcactagcg aggtggccct gaccaatact caggagcata tccttatgct cttgtcagag
    18121 gaatctttaa caaattcaga attggctcgt cgtctcaatg tcagtcaggc ggcagttacc
    18181 aaggccatta agtctttggt caaggaaggg atgttggaaa catctaaaga ttctaaagat
    18241 gcgcgtgtga ttttttatca gttgactgac ttggctcgtc caatcgctga ggagcaccac
    18301 catcaccatg agcatacact tttaacctat gaacaagtgg cgactcagtt tactccaaat
    18361 gaacaaaaag tgattcagcg gtttttgact gctttagtag gagaaatcaa ataatgagat
    18421 atattacggt agaggatttg tccttctatt atgataagga gcctgttctt gaacatatca
    18481 attattgtgt tgatagtggg gaatttgtta ccttgactgg ggaaaatgga gcggctaaga
    18541 cgacgctcat caaggctagt cttggaattc tgcaaccacg cattggaaag gtggctattt
    18601 caaagacaaa tacgcaaggt aagaaattga gaatagccta tcttcctcaa caaattgcca
    18661 gttttaatgc tggttttcca agtacggtct atgaatttgt caagtcgggt cgctatccga
    18721 gaaaaggctg gttccgtcgt ttgaatgctc atgatgagga gcatatcaag gctagtctgg
    18781 actcagttgg catgtgggaa catcgagaca aacgcttggg gtctctatct gggggacaaa
    18841 agcagcgagc ggtaattgcg cgtatgtttg cttctgaccc tgatgtgttt atcctagacg
    18901 agccgacaac ggggatggat gcaggaagta aaaatgaatt ttacgaactc atgcaccaca
    18961 gcgcccatca tcatggcaag gctgttttga tgattaccca tgaccctgaa gaagttaagg
    19021 attatgcgga tcgcaatatt catctagtcc gtaaccaaga ctcgccatgg cgttgtttca
    19081 atgttcatga gaatggccag gaggtgggcc atgcttagtt tattatctta cgactttata
    19141 cagcgcgcct ttttggcggt tattgctatg agtcttttct caccggtatt gggaaccttc
    19201 ctcatcttgc gtcgtcagag tttgatgagt gataccctta gccacgtctc actttcaggt
    19261 gtagcctttg gtctggtttt ggggatttct ccaactgttt ctactattgc cattgtcttg
    19321 attgcggcgg tctttctgga gtatctccgt acggtttaca agagctttat ggaaatcggg
    19381 acagctatcc tcatgtcaac aggtctggct gtttctctga ttgtcatgag caagggtaaa
    19441 agctcgagtt caatgagttt ggaccaatat ctctttggtt cgatcgtgac tatcagtgaa
    19501 gaacaggtca tttccctctt tgtcattgcg gtggttgttt tgattttgac ctttctcttt
    19561 cttcgtccta tgtatatctt aacttttgac gaagatacgg cctttgtgga tggcttgcca
    19621 gttcgtacca tgtccattct ttttaacatg gtgacagggg tggctattgc ccttatgatt
    19681 cctgcagcag gagctcttct ggtatcgacc attatggtct tgccagctag tattgccctg
    19741 cgtctgggga aaaactttaa atcggttatg ctgcttgcca gtgcgattgg ctttttggga
    19801 atggtagcag gactttacat ttcctactat gcagaaacac ctgcaagtgc aagtattacc
    19861 attatttttg taactgtctt tatactaatc agtttagtaa gacgttttat caaataggag
    19921 acgaacgtga aaaaaattag cttattacta gccagtctat gtgccttgtt tttagtggct
    19981 tgttccaatc aaaaacaggc agatggtaaa ctcaatatcg tgacaacctt ttaccctgtc
    20041 tatgaattta ccaagcaagt cgcaggagat acggctaatg tagaactcct aatcggtgct
    20101 gggacagaac ctcatgaata cgaaccatct gccaaggcag ttgccaaaat ccaagatgca
    20161 gataccttcg tttatgaaaa tgaaaacatg gaaacatggg tacctaaatt gctagatacc
    20221 ttggataaga aaaaagtgaa aaccatcaag gcgacaggcg atatgttgct cttgccaggt
    20281 ggcgaggaag aagagggaga ccatgaccat ggagaagaag gtcatcacca tgagtttgac
    20341 ccccatgttt ggttatcacc agttcgtgcc attaaactag tagagcacat ccgcgacagc
    20401 ttgtcagcag attatcctga taaaaaagag acctttgaga agaatgcagc tgcctatatc
    20461 gaaaaattgc aagccttgga taaggcttac acagaaggct tgtctcaagc aaaacaaaag
    20521 agctttgtga ctcaacacgc agcctttaac tatcttgcct tggactatgg actcaaacaa
    20581 gtcgcaatct caggcctttc tccagatgca gagccatcag ctgctcgctt ggcagaattg
    20641 acagagtatg tcaagaaaaa taaaatcgcc tatatctatt ttgaagaaaa tgcctcacaa
    20701 gcccttgcta acacactttc aaaagaagca ggtgtcaaaa ctgatgtcct caatccttta
    20761 gaaagtctga cagaagagga caccaaggct ggagaaaact acatttccgt gatggagaaa
    20821 aacctcaagg ctttgaaaca aacaacagac caagaaggcc cagcaatcga acctgaaaag
    20881 gcagaggata ccaagacagt ccaaaatggt tacttcgagg atgcagctgt caaggaccgc
    20941 accttgagtg actatgcagg taactggcaa tcagtttatc ctttccttga agacggcacg
    21001 tttgaccaag tctttgacta caaggctaag ttgactggta agatgaccca ggctgagtac
    21061 aaggcttact atacaaaagg ctatcagaca gatgtgacta agattaacat tactgataat
    21121 actatggaat ttgttcaagg tggacaaagc aagaaataca cttacaagta tgtcggtaag
    21181 aaaattttga cttacaagaa aggcaatcgt ggcgtgcgtt tcctctttga agccacagat
    21241 gctgacgctg gacaattcaa atatgttcag tttagtgacc acaatgttgc cccagttaag
    21301 gcagaacatt tccatatctt ttttggaggt acaagccaag aagctctatt tgaagaaatg
    21361 gataattggc caacctacta cccagataac ctatctggcc aagaaatcgc ccaagaaatg
    21421 ttggcgcatt gatgagaaat cgactagttc ataagagcta gtcggttttt tgatactaga
    21481 tggctaactt cattatagac ctttcagaac taagggaacc tgaaaaaata aataaaactc
    21541 ttgaaatatc tggacttata tgctagaatg tagttagtgt ataaggttca ttagaacacc
    21601 aaagccccta actagtgcca tagttaaggg cttttttgac gtatcttagc gatttaatgg
    21661 gtgtttatag gctagtcagt cggtctactt cttaccatct agccatttgc agacgaaata
    21721 caagataatt ccagctataa catctgctat aatagtaaga gcaagctctg gtataaggct
    21781 cattagtttc acctcctctc acgaacccat aggaacgtaa tcggtaaccg atgacaaaag
    21841 tattatatca cactaaattt agatcatcaa cctcacttaa tgcttgaact attgtagatt
    21901 atatgctaaa atgtagttaa ttgataaggt tcattagaac accaaagccc ctaactatgg
    21961 ccgtagttaa gggctttttt gacgtatctt agcgatttaa cgggtgttta taggctagtc
    22021 actcggtcta cttcttacta tctagccatc tgcagacgaa atacaagata attccagcta
    22081 taacatccgc tataatagta agagcgagct ctatgataag gctcattagt ttcacctcct
    22141 ctcacgaacc cataggaacg taatcggtaa ccgatgacaa aaatagtata ccacaataca
    22201 tttagatcat caaggtcact taattcttga aatatagggt ttaggcgaca aagtctttaa
    22261 aatcagaaaa acgcataata tcaggtgtgc aaaaacttga tactatgcgt tttattgtgg
    22321 gaaggtttac tccattttct cctgaaattg agtttttgtc cagcctctgt ttttagggtt
    22381 gctgagaaaa taatgtcatg tggtgaatat ttgtaaatca gtcagcagac agaacgaata
    22441 ctcttcgaaa atctcttcac atcatgtcag cttcgtcttt ccgtatatat gtgactgact
    22501 tcatcagttc tatctacaac ctcaaaacag tgtttcgagc tgactttatc agttttcaaa
    22561 tctgtacttt gagcaagctg agactagctt cctatttgat tttcattgaa tatcagaaac
    22621 ccattctcca tcaaataatt cgactgcgtc taataatttt tgatctggca cggtgtctga
    22681 aataaaggtt gtgtatttgg agaggggatt aattttaaaa aatccagtct tgtaaaattt
    22741 agaactatca atcagtaaga tggtttcatg ggctttgtca ataatattct tttttgaaat
    22801 agcttggctg agagaagctt cataaacata ttggtcatca atacctcttg ttgaacaaaa
    22861 tgctaaatcg atattaaaat gatctaataa agaattttcc ttatcatagt tgaccacgga
    22921 acaggattga tgtttgacct cgccagatgt gataaagatt ttggagctat ctttaacagt
    22981 ttcagatagg gtttgtgcag tatgtaaacc atttgtaaaa ataatcaaat tatcaagttc
    23041 agaaagatag ggacaaagtt cgtagacagt agtactggaa tccagataaa cacacatacc
    23101 agaccgaata aagtctttag cgagactagc gattagtctt ttttgcctag tactttctcc
    23161 ttcccgtatt tgatgagaaa gttcaattgt gttcatagag gacagggtca cgtatccgtg
    23221 ctttcttttg ataagacctt gattttctaa gaaaattaaa tcacgacgta aggtacttgt
    23281 gctggagaaa gtgatttctg ccagctcttt tacggcaatt ctttttttct ttttaataat
    23341 ttcaatcaat tcaagtacac gttcatcttt tatcataagc tcctcctaat ttatcatttc
    23401 aactatatta tagcacaaat tggaggaatt tgaattattt ttatgaatat tgggttaaca
    23461 tttgaacatt attcaagtaa gcgttcacat attgaaaaaa taaaatgtgg ggattataat
    23521 aaagttaatc aaggacgaag agagaagaaa aatggaagcg gttttagcaa tagatttagg
    23581 tgcgacttct ggaagagcaa tcgttggtta cctttctgaa aataaactag taatggaaga
    23641 aataaatcgc ttttctaatc tacctattag agtaaaaggg catttatctt gggatattga
    23701 ctttctacta gctaaaattc ttgaaagtat ccgcttggct aatactagtt acaagatttt
    23761 atctatcggt attgacacat ggggagttga ttttggactg attgataatg aaggtaagct
    23821 gttatcacaa cctgttcatt atcgtgatga aagaacaaag ggagtgttaa aggaaatatc
    23881 tgaaatgact gaattagaaa aactgtattc agagacagga aatcagatta tggagataaa
    23941 taccttgttt caactcttta aggcacgtca agaatctcct gactctttct ataagaccaa
    24001 taagattctt ttaatgccag atttgtttaa ttatctcttg acaggtaagt ttgctacaga
    24061 aaaaagcatt gcttcaacaa ctcaattatt tgatcctagg agtcaaaatt ggaatcagaa
    24121 tatcttaaaa ctatttgaat tggattcatc tttacttcct gaaattgttt cagagggaaa
    24181 tgttcttgga aggataaaaa aggagtatgg tttaggcgat attcctgttg tgaatgtttg
    24241 tagtcatgat acagcaagtg cgattgtctc agtacctaag acagaaggta gtttatttat
    24301 ttcatcaggt acttggtctt tggttggagt ggaacttact tcaccgattc ttactaccga
    24361 atccttcagt tatggattta caaatgaagt cggtaaagat ggagagatta catttctgaa
    24421 gaattgtaca gggttgtgga tcatagagga actaagacgt tcatttgaac gaagagggaa
    24481 agcctattct tttgatgata ttaggacaat ggtggagaaa gaaaaagaaa atcttcctct
    24541 gattgatact gaatcaactg aatttgcaac agaatctgat atgcacaaga ctttgacaga
    24601 atatctagct tatcatcatg aaactagaga gtggacagat ggacaactat ttaagattgt
    24661 ttatgaaagc ctagctgaaa cgtataggaa agcgatagag ttactagaag aactaactca
    24721 taaggtttat aagaggatat atgtgattgg aggaggtgct agagccagtt actttaacca
    24781 aatgattgct gatagaactg gtaaagaggt tcttacaggt tcgactgagg gtacagctgt
    24841 ggggaatatt gttgtgcagc tcatagctat gggacaatta aaagggatgg aagaagctca
    24901 ccatgttatt gaggagtttc tacaattaga gagttattac tcccaaaaga attaaaaaga
    24961 ttgagagttt gtaaatttgc ctccctcccc cttcttaagt tttgtacaag aaggggggat
    25021 aattggtgaa ttgaaaaata tttagtgttt tgatatgagg aggacaagaa tgtcagatgt
    25081 aaaacaagaa ttaattaagt atggcaagaa gctagtagaa acagatttga cgaaaggaac
    25141 aggtgggaat ctcagtgttt tcgatcgtga aaaacaattg atggcaatta ccccgtcggg
    25201 tattgatttc tttgaaatca aagaatccga tattgtagtg atggatatta atggaaatgt
    25261 tgtagaggga gaacgcttgc catctagcga atggtatatg catttgattc aatatcaaac
    25321 tcgtgatgat atcgatgcaa ttatccatgc tcatacaact tatgcaacag tattagcttg
    25381 tctcagagaa ccacttccgg ctagtcatta tatgattgca gtggcaggga aagatgttcg
    25441 ggtagctgag tatgcaacat atggtacgaa agaattggct gtgaatgcag ctaaagcaat
    25501 ggaaggtcgt agagcagttt tactagcgaa tcatggaatt ttagcaggtg cacaaaattt
    25561 attgaatgca tttaatattg ttgaagaagt tgaatattgt gcaaaaattt attgtttagc
    25621 taagaatttt ggagagccag tagttcttcc tgatgaggag atggatttaa tggcagaaaa
    25681 atttaaaaca tacggtcaga gaaaataggg aggatattaa tgttaaaaca tataccgaaa
    25741 aatatttctc cagatttatt gaagacttta atggaaatgg gacatggaga tgaaatagta
    25801 ttagctgacg cgaattatcc ttctgcctca tgtgcaaata agctaattcg ttgtgatggc
    25861 gtaaatattc cagaattatt agattccatt ctgtatttaa tgccattaga tagttacgtc
    25921 gatagttcaa ttcagtttat gaacgttgtt tcgggtgatg atattcctaa gatatggggt
    25981 acctatagac agatgattga aggtcatggt acagatctta aaacgattac ttatcttaga
    26041 agagaagact tttatgaacg tagtaagaaa gcttatgcta ttgttgctac aggagaaact
    26101 tcactttatg ctaatattat ccttaagaaa ggagtagttg ttgaaagaga aaatgtttaa
    26161 tagaggaatt ttagttgcca gtcatggtaa ttttgctagc ggagctctca tgaccgcaga
    26221 aatgtttgtt ggtgagacaa caaatgatag agttaggaca ttaggtttga tgcctggaga
    26281 gaatattgta gagtttgaac attattttaa aaatcaagta aatgaactgt tagactcaaa
    26341 tcaagaggtt atcgttttga ctgacttgat tggaggaagt cctaataatg tggctttgtc
    26401 acggttttta aatttggatt cagttgatat tgtaacaggg tttaatatcc ctctcctagt
    26461 ggaattaata tcaagttatg attcaaaaat caatttagaa gaaattgttc aaaatgctca
    26521 aaatagtttg tttaatgtta aacaacaact taacgtagag gaggaagagg atttatgtct
    26581 atagagtttg ttcgtattga tgaccgtctg gtacatggtc aagttgtcac tacgtggcta
    26641 aaaaagtatg atattgagca agttatcatt gttaatgatc gcatctcaga agataaaaca
    26701 cgacaatcta ttttaaagat ttctgcaccg gtaggtttaa aaattgtttt ctttagtgta
    26761 aaacggtttg tggaagtttt aaactctgtg ccaataaaaa agagaacaat gctgatatat
    26821 acaaatccaa aagatgtgta tgattctatt gaaggaaatt taaaattgga gtacctcaat
    26881 gtaggacaga tgagtaaaac ggaggaaaat gaaaaggtaa cgggaggtgt agctctaggt
    26941 gaagaagaca aatattattt taagaaaata gttgataagg gaacgagagt tgaaattcaa
    27001 atggttccta atgataaagt tacaatgttg gaaaaatttt tataaaaata atttaaggag
    27061 gtacagtata tgctattcac acaagcatta ctggtgacat tagttgggat tattgccact
    27121 attgactata atggaccgtt atttatgatt caccgtccgt tagttacaag tgcaatggtt
    27181 ggcttagtct taggagattt cacccaaggt gttcttattg gttcagctct tgaattaact
    27241 tggctcggtg taacaggtat tggaggttac actccaccag atactatttc aggtgcgatt
    27301 attggtactg catttggtat tttgtctggt caaggagaaa ctgctggtat cgctatagca
    27361 gttccaattg cagttgctac tcaacagttg gatgttcttg caaaaacttt agatgtttat
    27421 tttgtgaaaa aagctgataa tgatgctaaa aacggagatt attcaaagat cggtttttat
    27481 cattattcaa gtttggtttt aatcacttta tttaaaattg taccaatttt cctagctatt
    27541 atgcttggag gggaatatgt ggcagacttg tttgctaagg ttccaccaat cgttatgcag
    27601 ggacttaact ctgcaggtgc tttactacct tcaattggtt ttggtatgct tttaaatatg
    27661 atgctcaaga aaaatatgtg ggtattcttg ttgattggat tcatttgttc tgtgtatgga
    27721 ggaatgtcaa ccattgggat ctcactagtt ggtattgcgg tagcatactt ctacgatatg
    27781 attggaagta aaccacaaga aacaacttca agtagtgatg ttgaggagga tcttgatcta
    27841 tgatgaataa taaagtaact aaagttgaac ttaaaaaagt tttcaaacga agttttatgt
    27901 atggttcttc atggaactat gagagaatgc agaacctagg ttttctatat acaattcttc
    27961 cagtattgaa aaaactatac ccagacaaag attcagcttc tcctgcaatg aaacgtcacc
    28021 ttgagttttt caatactcat caaacagcgg caccatttat tcttggagtt acttccgcta
    28081 tggaagaaca agaaggaaat gaaggtgcag cttcaattac tggtattaaa gttggcttga
    28141 tggggccact ggctggtcta ggagatagtt tgttctggct gacactagtt cctatctgtt
    28201 ttagtattgg tgcgtcttat tctaaagacg gcggtgcttt aggtatcttt atcgccttaa
    28261 tattgtttaa tattattaat attcctgtta aatatttcgg tttgaaatat gggtatacta
    28321 agggttctag tcttatccaa gaaaataata caaaaggaac attgaatcgc gttacgagta
    28381 tggcgacagc attagggcta gtactagtgg gtggtttgat tccatcaatg gttggtatta
    28441 attttggatt agaatttaag cagggggaac ttgttatttc tgttcaagaa atgattacaa
    28501 aattaattcc aggatttatc cctatggctt tgactttatt aatgtgtaaa ttaattagaa
    28561 aaggaaagaa tccggttgta ctaatcttta gtgttatggc tattggagtt atcctagttg
    28621 ttttaggaat tttgaagtag tagaaagtgt ggaggtggta tttgggatat cacctccatt
    28681 ttggaagaga ggtaaagagt gaaattatgg tataagaaag ctgccgcaaa ttggaatgaa
    28741 gccttgccga ttgggaacgg tcatttaggt ggtatgattt atggttcagc tacaaaagaa
    28801 tgtattcaac taaacgatga gactatttgg tatagaggaa agtcagatag aaataatcca
    28861 gactcactat tgcatcttaa aaaaattcgg gaatatcttt tagatggaga aattcagaaa
    28921 gccgaagaat tgataaagtt aacaatgttt gctaccccaa gagatcaaag ccactatgaa
    28981 ttacttgggg aactttgcat tgagcatata gatattcagt cttgtgctct ttcattgtat
    29041 gaaagagagc tagatttaga tacagctatt tctaatgttg tgtttgagcc taatagttgt
    29101 aatttacaaa taaaaagaga atattttacg agttttaata agaatatttt atgttgccgt
    29161 atagtgtcat cagttcaaaa cacattaaat ttaaacatta atttgggtag aaataaacgg
    29221 tttaatgacg aagtatctaa actggattca agtacaattt taatgtcggc ctctgctgga
    29281 ggtagaaaag gtgttcagtt taaagtagta tgtcattcta aggttacgga tggtgaagta
    29341 agtgtattgg gagagacaat agttattcgg aatgctacag aggtatttct ttatctcaaa
    29401 tcaatgacgg attattgggg aaatatagat atttcttctc ttcagggaga atttagtagt
    29461 attgattact ttacagaaaa agatgaacat gtaaaaaaat atcaggagca atttaataga
    29521 gttgatttta aactagacta tagtaaaggt tgtcttagca ttccaacgaa tctacttctt
    29581 gaaaacacta aaaagtatag taactacttg actaacttgt tatttcatta tggaagatat
    29641 ctgttaatat cgtctagtca accgaatggt ttacctgcca atcttcaagg aatatggtgt
    29701 gatgaattaa atccaatttg gggttctaaa tatacgatta atattaatac tcaaatgaat
    29761 tattggatgg taggtccatg tgatttacca gaagtagaat atccattatt tgatatgctc
    29821 gaaagaatga gagaaccggg aagactaacc gctaagaaaa tgtatggagc tagaggtttt
    29881 acagcacatc ataatacgga tggttttggc gatacggctc cccaatctca tgccatgggg
    29941 gctgcaattt gggtattaac tattccatgg ttatgtactc atatttggga acactattta
    30001 tatttccaag atgagcgtat tcttacggaa cattttgaaa tgataaaaga agcatttctt
    30061 ttctttgaag attatttatt tgaggtggat ggctacttga tgacaggtcc aagtgtctca
    30121 ccggaaaata aatatcgctt aaaaaatggt attgaaggaa atgcttgtct atcatctaca
    30181 attgataatc aaattctaag atatttttgt gattcatgca ttggcattgc aaaacaatta
    30241 ggagacaatt cggattttat tagtcgtgtg aaggagttaa aaaagaaatt acctagaaca
    30301 aaaataggta gtaatgggca aatacaagaa tggctagagg attatgaaga agtagagcct
    30361 ggtcatagac acatttcacc tctatttggg ctttatcctt ataatgagat tgatattcat
    30421 aaaactccgg aattagcaga agcagctaaa atcactatca ataggagatt atcaaacgct
    30481 aactttttat cttcacagga tagggagcaa gcgattaata attggttagt aagtggtttg
    30541 catgctagta cacaaacagg ttggagtgct gcatggctga ttcatttttt tgcgagacta
    30601 tatcaaggtg aacctgctta taaccagatt aatggtttgt taaataatgc gactcttggc
    30661 aatttatttc ttgaccatcc accatttcaa attgatggta atttaggttt ggtgagtgga
    30721 atttgtgaat tattagtaca gagccatcat aattggttat cactaattcc agctttacct
    30781 tctgcttggt cagaaggaga agtgaaaggt ttcagagtaa gaggaggata taaggtatcg
    30841 tttgcttgga aaaatgggga tataacattc ctaaaattgg aaggaggaaa caaagatcaa
    30901 aaagtaagag taagaatata tggcaaaaat actgatgtac aaaatattga attggtattt
    30961 aattcagaaa aaattattga gttaaatttt taggtataag tcatgaataa agaaaaaata
    31021 aaaagaaaat taatcacaat attgtttgta tgtattggga tgttatgttt tggattgtta
    31081 gcaggagtta aggctgataa tcgtgttcaa atgagaacga cgattaataa tgaatcgcca
    31141 ttgttgcttt ctccgttgta tggcaatgat aatggtaacg gattatggtg ggggaacaca
    31201 ttgaagggag catgggaagc tattcctgaa gatgtaaagc catatgcagc gattgaactt
    31261 catcctgcaa aagtctgtaa accaacaagt tgtattccac gagatacgaa agaattgaga
    31321 gaatggtatg tcaagatgtt ggaggaagct caaagtctaa acattccagt tttcttggtt
    31381 attatgtcgg ctggagagcg taatacagtt cctccagagt ggttagatga acaattccaa
    31441 aagtatagtg tgttaaaagg tgttttaaat attgagaatt attggattta caataaccag
    31501 ttagctccgc atagtgctaa atatttggaa gtttgtgcca aatatggagc gcattttatc
    31561 tggcatgatc atgaaaaatg gttctgggaa actattatga atgatccgac attctttgaa
    31621 gcgagtcaaa aatatcataa aaatttggtg ttggcaacta aaaatacgcc aataagagat
    31681 gatgcgggta cagattctat cgttagtgga ttttggttga gtggcttatg tgataactgg
    31741 ggctcatcaa cagatacatg gaaatggtgg gaaaaacatt atacaaacac atttgaaact
    31801 ggaagagcta gggatatgag atcctatgca tcggaaccag aatcaatgat tgctatggaa
    31861 atgatgaatg tatatactgg gggaggcaca gtttataatt ttgaatgtgc cgcgtataca
    31921 tttatgacaa atgatgtacc aactccagca tttactaaag gtattattcc tttctttaga
    31981 catgctatac aaaatccagc tccaagtaag gaagaagttg taaatagaac aaaagctgta
    32041 ttttggaatg gagaaggtag gattagttca ttaaacggat tttatcaagg actttattcg
    32101 aatgatgaaa caatgccttt atataataat gggagatatc atattcttcc tgtaatacat
    32161 gagaaaattg ataaggaaaa gatttcatct atattcccta atgcaaaaat tttgactaaa
    32221 aatagtgagg aattgtctag taaagtcaac tatttaaact cgctttatcc aaaactttat
    32281 gaaggagatg ggtatgctca gcgtgtaggt aattcctggt atatttataa tagtaatgct
    32341 aatatcaata aaaatcagca agtaatgttg cctatgtata ctaataatac aaagtcgtta
    32401 tcgttagatt tgacgccaca tacttacgct gttgttaaag aaaatccaaa taatttacat
    32461 attttattga acaattacag gacagataag acagctatgt gggcattatc aggaaatttt
    32521 gatgcatcaa aaagttggaa gaaagaagaa ttagagttag cgaactggat aagcaaaaat
    32581 tattccatca atcctgtaga taatgacttt aggacaacaa cacttacatt aaaagggcat
    32641 actggtcata aacctcagat aaatataagt ggcgataaaa atcattatac ttatacagaa
    32701 aattgggatg agaataccca tgtttatacc attacggtta atcataatgg aatggtagag
    32761 atgtctataa atactgaagg gacaggccca gtcccttttc caacaccaga taaatttaat
    32821 gatggtaatt tgaatatagc atatgcaaaa ccaacaacac aaagttctgt agattacaat
    32881 ggagacccta atagagctgt ggatggtaac agaaatggta attttaactc tggttcggta
    32941 acacacacta gggcagataa tccctcttgg tgggaagtcg atttgaaaaa aatggataaa
    33001 gttgggcttg ttaaaattta taatcgcaca gatgctgaga ctcaacgtct atctaatttt
    33061 gatgtgattc tatatgacaa taatagaaac gaagttgcta agaaacatgt taataatttg
    33121 tcgggtgaat ctgttagtct agatttcaaa gaaaaaggag caaggtatat taaagttaaa
    33181 ttactaacga gtggagtgcc tttgagttta gcagaagtag aggtttttag agaatcagat
    33241 ggtaagcaat ctgaagagga tatagataaa ataacagaag ataaagtagt ctctacaaat
    33301 aaggtagcta ctcaaagttc aaccaattat gagggtgtag ctgctttagc agttgatggt
    33361 aataaagatg gagattacgg acatcattcg gtgactcata ctaaggcaga ttctaacgct
    33421 tggtggcagg tcgatctggg agaagagttt acggtttcta aagttgatat ttataataga
    33481 acagatgccg aacctcagcg tttatctaat tttgatgtta tttttctatc ttcatcagga
    33541 gaagaagttt ttagaagaca ttttgataaa gtagttgatg gtttgttatc tttaaaagta
    33601 ccttctgtag gggctaagct agtcaaaata gaattaaaat cagcagctat tccgttaagt
    33661 ttagcggaag ttgaagtcta tggttcaaag agaactccga agaaactttc taatattgca
    33721 ttaaccaaag aaactcgaca gagttcaacg gattacaatg gtttttctcg tctagcagtt
    33781 gatggaaata aaaacggaga ttatggtcat cattcagtga ctcataccaa aggagattct
    33841 ccttcatggt gggagataga tttagcacaa accgaagaat tagaaaagtt aattatttat
    33901 aatagaacag atgctgaaat tcagagatta tcaaattttg atattattat atatgattca
    33961 aataatcatg aagtttttaa acaacatatt gacagtttag aaagcaataa tctatccata
    34021 gacttaaaag ggctgaaggg aaaaaaggtt agaatttctt tgagaaacgc aggaattcct
    34081 ttaagtttgg cagaggtaga ggtttatact tataagtaat tttaaaaatt atcatcggta
    34141 gtatgaaaga aacagaaaaa taagaggaaa atagtatgat tcaacatcca cgtattggta
    34201 ttcgtccgac tattgatggt cgtcgtcaag gtgtacgcga atcacttgaa gtacaaacaa
    34261 tgaacatggc taaaagtgtg gcagatttga tttcaagcac attgaaatat ccagatgggg
    34321 aacctgtgga atgtgtgatt tctccatcta ccattggtcg tgttccagag gctgcagctt
    34381 cccatgagtt gtttaaaaaa tcaaatgttt gcgcaacaat tacagttaca ccatgctggt
    34441 gttatggtag tgaaactatg gatatgtctc cagatattcc tcatgctatt tggggattta
    34501 atgggacaga acgcccagga gctgtctatc ttgcagctgt actagcttca catgctcaaa
    34561 aagggattcc agcctttggg atttatggta gagatgttca ggaagctaat gatacagata
    34621 ttccagaaga tgtcaaagaa aaacttttac gttatgcgcg tgcagctctt gcaactggct
    34681 tgatgagaga cactgcttac ctatcaatgg gtagtgtttc gatggggatt ggtggttcta
    34741 ttgtaaatcc ggatttcttc caagaatact taggaatgcg aaatgaatcg gtagatatga
    34801 cggagttcac acgccgtatg gaccgtggta tttacgaccc tgaagagttt gaacgtgcta
    34861 tggtttgggt aaaagaacat atcaaagaag gagttgaccg aaatcgtgag gatttgattc
    34921 tttctaaaga agagaaagaa aaacaatggg aatttgttat taagatgttc atgattggac
    34981 gtgacttaat ggttggtaac ccaagacttg ctgaacttgg ttttgaggaa gaagcagttg
    35041 gtcaccatgc tttagtagct ggtttccaag gtcaacgtca gtggacagac cattttccaa
    35101 atggagattt tatggaaact ttcctcaata ctcagtttga ctggaatggt attcgaaaac
    35161 catttgtatt tgcgacagag aatgattcac taaatggtgt gtctatgctc tttaattatc
    35221 tactaacaaa tactccacaa atctttgctg atgtgcgtac ttattggagt ccagaggctg
    35281 ttgaacgtgt aacaggatat actttagagg gtcgtgctgc agctggcttc ttacatctaa
    35341 tcaactctgg ttcttgtaca ttggatggta caggtcaagc tactcgagat ggcaaacctg
    35401 ttatgaaacc attctgggag ttggatgaaa gtgaagtaca ggctatgctt gaaaatacag
    35461 acttcccacc agcaaaccgc gagtacttcc gtggaggagg attctcaact cgtttcttga
    35521 cgaaggggga tatgccagta acaatggtac gtctcaatct tctaaaaggg gttggtccag
    35581 tgctacaaat tgcagaaggt tacacacttg aacttcctga agatgttcac catactttag
    35641 ataatcgtac agattcagga tggccaacta cttggtttgc tccacgtttg acaggaaaag
    35701 gtgctttcaa gtctgtctat gacgtcatga ataattgggg agctaatcac ggagccataa
    35761 catatggaca cattggagca gacttgatta ccttggcttc tatgttgaga attcctgtca
    35821 atatgcataa tgtacctgag gaagatatct ttagacctaa aaattggtcc ttatttggaa
    35881 cagaagatct agaatcagca gactatcgtg catgtcagtt gttgggacca ctacataaat
    35941 aaaacttgtt tatataggag gtgaacttac gtccctccta tccttttaaa aagatttgtt
    36001 aaacaattca caaataattg aaaacgaata caaaaagtaa tataatgatg ttaaatagat
    36061 agcgcggagg cgcaggagga aaattatatg gctatatttt atgttccggc agtcaacctt
    36121 attggaaaag gtgttgtaaa tgaagtgggt ccttatatca aggaacttgg ctataaaaag
    36181 gcacttttgg tgacagataa gtacatcgaa ggcagtgata ttttacctaa gactttaaaa
    36241 ccactggata cagaaggaat cgaatatgtc atctttagcg atgtagagcc aaaccctact
    36301 tgtaaaaatg tcacagatgg ggtagctgct ttgcaagaac atggctgtga ctttatcatc
    36361 agtcttggcg ggggttctcc acaggatgca gctagttgta tttctatcat ggctacaaat
    36421 ggtggaaaac cacaggatta tgaagggctt cataagtctg ctaaaaaagg tttgccagtt
    36481 gtggctatca atacaacggc aggtacatca gcagaaatta ccattaacta tgtgattact
    36541 gatgaagaac gcaaggttaa gatggtaatg gttgacaaga atagccttgc cttgatttct
    36601 gtcaatgacc ctgaactcat gctttccaaa cctaaaggcc tgactgctgc tactggtatg
    36661 gatgctctga ctcatgctgt tgaagctttg gtaacacctg gtgcttatga tgtaaccaag
    36721 aaactgtcta ttggtgctat tgagcttatc aaggaatatc ttcctcgtgc tgtagaaaat
    36781 ggacatgata ttgaagcgcg tgaaggtatg gtcaatgcca tcttccttgg tggtatgagc
    36841 tttaataatg ctggtcttgg ctatgttcac tcaatggctc accaactcgg tgcagtatat
    36901 aatttgccac atggcgtgtg ctgtgccatg ttgctaccag ttatagaacg tgaaaatgct
    36961 aaacgtgtac cagaagcttt ccgcaatgtt gccaaagcct tgggacttca tgtagaaggt
    37021 aaatcagatc aagaatgtgc cgattatgcg attgctgaga ttgagaagct ttctgagaca
    37081 gtaggtattc ctaagaaact gactgaactt ggtattgaag aaaaagattt cgactttgaa
    37141 tacctttcta agaatgcctt gattgatgcc tgcgcaccag gaaatccatt tatgccaacc
    37201 ttagaagaaa cgattgcctt ttataaagag ttattttagc aagagattgg acgacaatag
    37261 gacaattcac ctctaattat tgacatttca ggaaaaatcg cagtaaaaac ggcacagcct
    37321 tctttaaatg tgctataata ctagaaaaat acttgtggag gttccattat ggcaatattt
    37381 ttcatgattt ttctgattgt ttgtgtgctc ctattggtga tagtcacact gagtacagtt
    37441 tatgtggttc gtcagcagtc ggtggcgatt attgaacgct ttgggaaata ccaaaaggtt
    37501 gctaatagcg gtattcatat tcgcttgcct tttgggattg actcgattgc agcacggatt
    37561 cagttgcgct tgttgcaaag tgatattgtg gttgagacta agaccaagga caatgtgttc
    37621 gttatgatga atgtagcgac tcagtaccgt gtcaacgagc agagcgtgac agatgcttac
    37681 tataaactca tacgtccaga atctcagatt aaatcttata tcgaagatgc tcttcgctct
    37741 tctgttccaa aattaacctt ggatgaattg tttgagaaaa aagatgagat tgcccttgag
    37801 gttcaacacc aagtagcaga agaaatgacc acttacggct acattatcgt gaaaaccttg
    37861 attaccaagg tcgaaccaga tgcagaagtt aagcaatcta tgaatgaaat caatgcggcg
    37921 caacgtaagc gggtcgcagc acaagaattg gcggaagctg acaagattaa aattgtcact
    37981 gcagctgaag ccgaagcaga aaaagaccgc cttcatggtg tggggattgc ccaacaacgt
    38041 aaggcgattg tggatggatt ggcagagtct atcaccgaac tcaaggaagc caatgttggc
    38101 atgacagaag aacaaatcat gtctatcctc ttgaccaacc agtatttgga taccttgaat
    38161 acctttgcct ctaaaggaaa tcaaaccatc tttttaccaa atactccaaa tggtgtggat
    38221 gatatccgta cacaaatctt gtcagccctt cgcgctgaga agaaataata gactaatact
    38281 cttcgaaaat ctcttcaaac tacgtcagcg tcgtcttgcc gtatagatgt tactgacttc
    38341 gtcagttcta tctgcaacct caaaacagtg ttttgagctg acttcgtcag tcttatctac
    38401 tacctcaaaa cggtgttttg agcaacctgt agctagtttc ctagtttgct ctttgatttt
    38461 cattgagtat aaagagcttg gcaacaggct ctttttgtat tgcgtttatt aagaaaaaca
    38521 aaaaacatcg atatacattt aactaaaaat tattgtatgt tatctccctt aattaggaat
    38581 gataagggaa taactagaaa gatttgtgaa tacaaactat ttctgatata caaaatatac
    38641 agtaataatg aatgatggga gatgggatga aagaatttca atttgagaga aagcagcgtt
    38701 tttctttgag gaaatatgca ataggagctt gttcggtctt gctaggaacg agtttatttt
    38761 ttgctggtat gggtgctcag cctgtacagg atacagaaac gagttcagca ctaatttcaa
    38821 gtcattattt ggatgagcag gatttatctg aaaagctgaa atctgagttg caatggtttg
    38881 aattagaaaa caagcttttg aacttatggg agcattaggt tactatgaag gatttgttcc
    38941 ttatgtttca aatcaatacc aaaaccaagc tgaagaagaa tacaaaccgc tatctgataa
    39001 atatattttc gaaaaaatct taggaaaaac atatgcagcc ttcaaaaaag atcaaattaa
    39061 tgagcgtgtc gagaaattag gtaagttaaa acctattaca ataaattaca acggaaaatc
    39121 agaagtaatt gatagtaaag aaaaattaca agagcttatg aataaagccg ttaaagacga
    39181 agtggctcaa atatagtaaa atgaaataag aacaggacaa atcgatcagg acagtcaaat
    39241 cgatttctaa aaatgtttta gaagtagagg tgtactattc tagtttcaat atactataaa
    39301 atcaggcaat accacggcta aaaagtttga gtttatcgaa ataccagtgc aaaaactgaa
    39361 aaaagcaatt tataaagctc atctcaaaga ttcagat
//
LOCUS       DBEJJV010000018        37839 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.018, whole genome shotgun sequence.
ACCESSION   DBEJJV010000018 DBEJJV010000000
VERSION     DBEJJV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 37839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37839
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.018"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            163..951
                     /gene="codY"
                     /locus_tag="ACL3GT_001054"
     CDS             163..951
                     /gene="codY"
                     /locus_tag="ACL3GT_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HGR0516732.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            951..1526
                     /locus_tag="ACL3GT_001055"
     CDS             951..1526
                     /locus_tag="ACL3GT_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HGR0516733.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1608..1693
                     /locus_tag="ACL3GT_001056"
     tRNA            1608..1693
                     /locus_tag="ACL3GT_001056"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1642..1644,aa:Leu,seq:aag)
     gene            1976..3106
                     /locus_tag="ACL3GT_001057"
     CDS             1976..3106
                     /locus_tag="ACL3GT_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516734.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(3229..3399)
                     /locus_tag="ACL3GT_001058"
     CDS             complement(3229..3399)
                     /locus_tag="ACL3GT_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002668516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516735.1"
                     /translation="MEIKEQTRKLAVSYSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEYKEHHNIDV"
     gene            3607..4365
                     /locus_tag="ACL3GT_001059"
     CDS             3607..4365
                     /locus_tag="ACL3GT_001059"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0516736.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4453..4965
                     /locus_tag="ACL3GT_001060"
     CDS             4453..4965
                     /locus_tag="ACL3GT_001060"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HGR0516737.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5147..6091
                     /gene="metA"
                     /locus_tag="ACL3GT_001061"
     CDS             5147..6091
                     /gene="metA"
                     /locus_tag="ACL3GT_001061"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HGR0516738.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            6100..6777
                     /locus_tag="ACL3GT_001062"
     CDS             6100..6777
                     /locus_tag="ACL3GT_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0516739.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            6875..7633
                     /gene="tpiA"
                     /locus_tag="ACL3GT_001063"
     CDS             6875..7633
                     /gene="tpiA"
                     /locus_tag="ACL3GT_001063"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HGR0516740.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7671..9176
                     /gene="lytC"
                     /locus_tag="ACL3GT_001064"
     CDS             7671..9176
                     /gene="lytC"
                     /locus_tag="ACL3GT_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HGR0516741.1"
                     /translation="MSVTFFIGEQRLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            9674..10192
                     /locus_tag="ACL3GT_001065"
     CDS             9674..10192
                     /locus_tag="ACL3GT_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HGR0516742.1"
                     /translation="MVELKKEAAKDVATLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGHLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLAIYRYLITLFQKALDVTDEEGDDVTNDIFVGAKAELEKTVW
                     MLAAELGQAPGL"
     gene            10322..10828
                     /locus_tag="ACL3GT_001066"
     CDS             10322..10828
                     /locus_tag="ACL3GT_001066"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HGR0516743.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            10828..10998
                     /locus_tag="ACL3GT_001067"
     CDS             10828..10998
                     /locus_tag="ACL3GT_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516744.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            11030..12262
                     /gene="clpX"
                     /locus_tag="ACL3GT_001068"
     CDS             11030..12262
                     /gene="clpX"
                     /locus_tag="ACL3GT_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HGR0516745.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12271..12858
                     /gene="yihA"
                     /locus_tag="ACL3GT_001069"
     CDS             12271..12858
                     /gene="yihA"
                     /locus_tag="ACL3GT_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HGR0516746.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHAPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            12869..13249
                     /locus_tag="ACL3GT_001070"
     CDS             12869..13249
                     /locus_tag="ACL3GT_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HGR0516747.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13301..14191
                     /gene="rapZ"
                     /locus_tag="ACL3GT_001071"
     CDS             13301..14191
                     /gene="rapZ"
                     /locus_tag="ACL3GT_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HGR0516748.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14188..15165
                     /locus_tag="ACL3GT_001072"
     CDS             14188..15165
                     /locus_tag="ACL3GT_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HGR0516749.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15162..16073
                     /gene="whiA"
                     /locus_tag="ACL3GT_001073"
     CDS             15162..16073
                     /gene="whiA"
                     /locus_tag="ACL3GT_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HGR0516750.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16107..17075)
                     /locus_tag="ACL3GT_001074"
     CDS             complement(16107..17075)
                     /locus_tag="ACL3GT_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HGR0516751.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEDYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQTLQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            17211..18068
                     /gene="cdaA"
                     /locus_tag="ACL3GT_001075"
     CDS             17211..18068
                     /gene="cdaA"
                     /locus_tag="ACL3GT_001075"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HGR0516752.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYMSTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            18055..18834
                     /locus_tag="ACL3GT_001076"
     CDS             18055..18834
                     /locus_tag="ACL3GT_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HGR0516753.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            18858..20210
                     /gene="glmM"
                     /locus_tag="ACL3GT_001077"
     CDS             18858..20210
                     /gene="glmM"
                     /locus_tag="ACL3GT_001077"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HGR0516754.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            20284..20658
                     /locus_tag="ACL3GT_001078"
     CDS             20284..20658
                     /locus_tag="ACL3GT_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HGR0516755.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            20660..21508
                     /locus_tag="ACL3GT_001079"
     CDS             20660..21508
                     /locus_tag="ACL3GT_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0516756.1"
                     /translation="MKLAVFTDSSAYLSAEILQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            21785..22552
                     /gene="dapB"
                     /locus_tag="ACL3GT_001080"
     CDS             21785..22552
                     /gene="dapB"
                     /locus_tag="ACL3GT_001080"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HGR0516757.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            22549..23748
                     /locus_tag="ACL3GT_001081"
     CDS             22549..23748
                     /locus_tag="ACL3GT_001081"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HGR0516758.1"
                     /translation="MRLMQMPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIH
                     DVDIATSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSA
                     VSFVRSLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDA
                     LRIMRGFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLA
                     SMIESQAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKS
                     WKTSRQFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVI
                     KETYQSLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIH
                     AYLREKK"
     gene            23745..25616
                     /locus_tag="ACL3GT_001082"
     CDS             23745..25616
                     /locus_tag="ACL3GT_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0516759.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAQDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(25759..26943)
                     /gene="mntE"
                     /locus_tag="ACL3GT_001083"
     CDS             complement(25759..26943)
                     /gene="mntE"
                     /locus_tag="ACL3GT_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HGR0516760.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            27247..29943
                     /locus_tag="ACL3GT_001084"
     CDS             27247..29943
                     /locus_tag="ACL3GT_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HGR0516761.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            29956..30747
                     /gene="yghU"
                     /locus_tag="ACL3GT_001085"
     CDS             29956..30747
                     /gene="yghU"
                     /locus_tag="ACL3GT_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HGR0516762.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLRTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTEDVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            30863..31273
                     /locus_tag="ACL3GT_001086"
     CDS             30863..31273
                     /locus_tag="ACL3GT_001086"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0516763.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            31285..32880
                     /locus_tag="ACL3GT_001087"
     CDS             31285..32880
                     /locus_tag="ACL3GT_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516764.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGRTFEGQVGKDSYLKTFKVQ"
     gene            33059..33223
                     /locus_tag="ACL3GT_001088"
     CDS             33059..33223
                     /locus_tag="ACL3GT_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HGR0516765.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKENKDKFLSILTSLAGLALV
                     LVAVWLGWPK"
     gene            33302..34030
                     /gene="yaaA"
                     /locus_tag="ACL3GT_001089"
     CDS             33302..34030
                     /gene="yaaA"
                     /locus_tag="ACL3GT_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HGR0516766.1"
                     /translation="MKILIPTAKEMNTDLPSIETTLLRSESQAVLDALALYSASQLES
                     FYKVSAEKAAEECQNIQALKRQTAQHYPALKLFDGLMYRHIKRDKLTEVEQAYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDEAVKQEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(34081..35565)
                     /locus_tag="ACL3GT_001090"
     CDS             complement(34081..35565)
                     /locus_tag="ACL3GT_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator PRD
                     domain-containing protein"
                     /protein_id="HGR0516767.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            35781..>37839
                     /locus_tag="ACL3GT_001091"
     CDS             35781..>37839
                     /locus_tag="ACL3GT_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HGR0516768.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETK
                     PAVTTTERSAVDSAILPISTAAKVETTSAPASTNEILKPSLSLSDARQNPAIRKEDVD
                     RGYSGFRTAGSGFRAAGSGFRAAGPENKPILNPNNTIAFSDISQGLHSFRGIGHSRGG
                     REIHYDVTTVRRGNRLNFTIKYSGPGEFVNNNFILDKGDGFGNPSNATITSSNPRVRE
                     QSKSISQGANYVSHSGYSMTSATSTNTEQTIRFSLPIINPNGDLSVRLKPVTFNVDQG
                     GGGAATSNDPYSNSNYYHRANPLLLDANPYGGTNNKTVSEDIDFQTVYLPTSKLPEGQ
                     TRLVREGEKGQRQITYKVHRFGNETLLGLPISNRVTKEAKPRIMQIGVAKELIDTVKP
                     RVDQNKVGDTNNLTFYLDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDQGERGLTGAK
                     GEKGDRGERGLTGAQGAKGEKGDRGERGLTGAQGAKGEKGARGERGLTGAQGAKGEKG
                     DRGE"
BASE COUNT        11351 a         6933 c         8628 g        10927 t
ORIGIN      
        1 aaaataggcg acttgtcaat agaaaaggaa caatttaatt aaaaatattc tggtttttaa
       61 ttaaattgta agtcaatgca agtcaataag gaattttcag ataattattg aaaaagagac
      121 gtttttatgt tataatgata gcgattaaat tcgaggtgaa aaatggcaca tttattagaa
      181 aaaactagaa aaattacatc aattttgaaa cgctcagagg agcagttgca ggatgagctc
      241 ccttacaacg ctattacgcg tcagttagcg gatattattc attgcaatgc ctgcattatc
      301 aatagtaagg gacgtctgct tggctatttt atgcgttata aaacaaatac agatcgcgta
      361 gagcaattct tccaaactaa gattttccca gatgactacg ttcaaggggc taatatgatt
      421 tacgaaacag aagcaaactt gcctgttgag catgatatga gtattttccc tgttgagagt
      481 agagatgatt ttccagatgg cttgacgact attgcaccga ttcatgtatc ggggattcgc
      541 cttggttctt tgattatttg gcgtaatgat aaaaaattcg aagatgagga cttggttctt
      601 gttgagattg ccagtaccgt tgttgggatt cagcttctta acttccaacg tgaagaagat
      661 gagaaaaata ttcgtcgtcg tactgctgtc accatggcgg tcaataccct ttcttactcc
      721 gaactccgtg ctgtttcagc aattttaggg gaattaaatg gaaatgaagg gaagttgact
      781 gcgtcagtga ttgcagatcg tatcggaatc actcgctctg tgattgtcaa tgctcttcgt
      841 aaacttgagt ctgcggggat tattgaaagt cgctcacttg gaatgaaggg aacctatctt
      901 aaggtcttga tttcagatat ttttgaagaa gtgaagaaaa gagattacta atgacaaagg
      961 ctttaatttc gattgattat acagaagatt ttgttgctga tagtgggaag ctgacagcag
     1021 gtgctccagc tcaggcgatt tcggatgcca tcagcaaggt aactcgatta gcttttgaac
     1081 gaggagatta tatcttcttt actattgatg ctcatgaaga aaacgattgt ttccatccgg
     1141 aaagtaagtt atttcctcct cataatctga ttgggacgag tggacggaat ttatatggag
     1201 atttggggat cttttatcaa gagcatggtt cagacagtcg tgtcttttgg atggataaac
     1261 gccattactc agctttttca gggactgacc tagatattcg tttgagagag cgtagagtgt
     1321 ctaccgttat cttaacaggt gtcttgacgg atatctgtgt cctacataca gctatagatg
     1381 cctataatct aggatatgac atcgagattg ttaaaccagc tgttgcttcc atctggcctg
     1441 aaaatcatca atttgcccta ggtcatttca aaaatacact cggagctaag ttagtagatg
     1501 aaaatctaaa tgaactttct gagtaacctg gttggtgaaa atgaaaaaat ttgaaaaaaa
     1561 gtgttgacaa gcatcccaaa agttgatata ctagtaaagt aatcgatgcg gggatggcgg
     1621 aattggcaga cgcgcaggac taaggatcct gtgaccgctt taggtcgtga gggttcaagt
     1681 ccctctctcc gcataggaaa agagttagct aaagctagct cttttgtatt tctctaaaaa
     1741 attagaatcc agtcaaatgt agtggagaat cagcgaaaat atgggaaaac tgatccttgt
     1801 ttctgctttt gtcatagaag aataataaag attatcttct tcaaattctc cgatattctc
     1861 taaagttttg tgcaagttgc acagaacttt tttatttttt tggtcatctt gccatagaaa
     1921 tataaagcgt tttcatctat aatataatta tcaaaagaca aaaggagttc acctcatggt
     1981 agaattgaat cttaaaaata tttacaaaaa atatccaaac agcgaacact attcagttga
     2041 agatttcaac ttgaacatca aagataaaga atttatcgtt ttcgtaggac cttcaggatg
     2101 tggtaaatca actacactcc gtatgattgc tggtcttgaa gacatcacag aaggtactgc
     2161 atctatcgat ggcgtggttg tcaacgacgt agctccaaaa gaccgtgata tcgccatggt
     2221 attccaaaac tacgctcttt acccacacat gactgtttat gacaacatgg ctttcggttt
     2281 gaaattgcgt aaatacagca aagaagacat taacaaacgt gttcaagaag cagctgaaat
     2341 acttggattg aaagaattct tggaacgtaa accggctgac ctttcaggtg gtcaacgtca
     2401 acgtgttgcc atggggcgtg cgattgtccg tgatgcgaaa gtattcttga tggacgaacc
     2461 tttgtcaaac ttggatgcca aacttcgtgt atcaatgcgt gctgaaatcg ctaaaattca
     2521 ccgtcgtatc ggagctacaa ctatctatgt aactcacgac caaacagaag cgatgacact
     2581 tgcagaccgt atcgttatta tgtcagctac taagaaccct gctggtacag gtactatcgg
     2641 acgtgtagaa caaatcggta ctcctcaaga agtttacaaa aatccagtta acaaattcgt
     2701 tgcaggattc atcggaagcc cagctatgaa cttcatcaac gtgaaattgg ttggtagcga
     2761 aattgtttct gacggtttcc gtttgaaagt gccagaagga gcattgaaag ttcttcgtga
     2821 aaaaggctac gaaggaaaag aattgatctt tggtatccgt ccagaagacg tgaatgcaga
     2881 acctgctttc cttgaaacat tcccagactg tgttgtaaaa gcgactatct ctgtatcaga
     2941 actgcttggt tcagaatctc acctttactg ccaagttggt aaagacgagt ttgttgcaaa
     3001 agttgatgct cgtgactact tgcaaacagg tgcaacagtt gagcttggat ttgacttgaa
     3061 caaagcacac ttcttcgatg tagaaactga aaaaacaatc tactaagaat aaataaaatt
     3121 caaagcacta caagaaaaga tatctcttta tcaattgtag tggagagata tcagttaatc
     3181 tagggagaga aacaaaatgc ttctctcctt tttgctaggg aagtcatatt atacatctat
     3241 attgtgatgc tctttatact cttcgaaaat ctcttcaaac cacgtcaacg tcgccttgcc
     3301 gtacgtatga ttactgactt cgtcagtttt atctgcaacc tcaaagctgt actttgagta
     3361 gcttacggct agtttcctag tttgctcttt gatttccatt gagtattatt tgtgggtacc
     3421 atctacaagt gaagctatat gcgtaaacta cgtgagcaat tgaattcgaa ctagagaggt
     3481 aataataaat ttatgctata gttatggtga cttgtatgct tttgattcta gtttatcaaa
     3541 taatagatta gaattgtcag ataatatcat tttgtgttat aatgaagaaa aaacagaggt
     3601 gttcaaatgt cagaagcagg tcataagttt ttagcaaaat tggggaaaaa acgcttacgt
     3661 ccaggtggaa agcgtgccac agattggtta attgcagaag gaggattttc aaaagaaaag
     3721 agaatactag aggttgcgtg taatagggga actacagcaa ttgagttggc acagcgtttt
     3781 ggttgcaaga taactgctgt tgatatggat gctcaagctt tagaagtggc taaaaaatct
     3841 gctggaacgg caggtgttgc tcatttaatc agttttgaaa gagcaaatgc aatgaaactt
     3901 ccttatcaag atgctagttt tgatattgtt ataaatgaag ctatgctgac tatgcaagcc
     3961 gatcaagcta agaaaaaatg tgtaatggaa tatctaaggg tattaaaacc tggaggtctt
     4021 ctcttgacac atgatgtgct tcttaaggaa gctaaagagt ctatcagaca ggaattatca
     4081 caagcaattc atgtaaatgt aggtccttta actcaagatg gttgggaaca ggtgatgata
     4141 gaatcaggtt attgtgatgt gaaagcattg actggtgaaa tgacattaat gaaattatcg
     4201 ggtatgattt atgacgaagg tttgctagga actttgaaaa tttgtgtaaa tgcttgtaaa
     4261 aaggagaata gaaagcagtt tttaactatg tataaaatgt ttgctaagaa taaacagaaa
     4321 ttgggcttta ttgcgatggc tagttataaa tcgtcaaaac gttagataat tattgaagtt
     4381 aacttttcct tttttctttc ttaaaaaata tgctataata gagagtaaaa aactttgaaa
     4441 gaaagaaaaa agatgaattt aaaagattac attgcaacaa ttgaaaatta tccaaaggaa
     4501 ggcattacct tccgtgatat tagtcctttg atggctgatg gaaatgctta tagctacgct
     4561 gttcgtgaaa tcgttcagta tgctactgac aagaaagtcg acatgatcgt gggacctgaa
     4621 gctcgtggat ttatcgtggg ttgtccagtt gcctttgagt tgggaattgg ttttgcgcct
     4681 gttcgtaagc caggtaaatt gccacgcgaa gttatttctg ctgactatga aaaagagtac
     4741 ggtgtcgata ccttgactat gcacgcggat gccattaagc caggtcaacg tgttcttatt
     4801 gtagatgacc ttttggcgac aggtggaact gttaaggcaa ctatcgagat gattgaaaaa
     4861 cttggtggtg ttatggcagg ttgtgccttc cttgttgaat tggatgaatt gaacggccgt
     4921 gaaaaaatcg gtgactacga ctacaaagtt cttatgcatt attaatgaaa acagtcccta
     4981 gggctgtttt ctctacacta ggatataaaa atagactata actagttaga gaaaaactat
     5041 aattgaaaac tatatcttct tgcagtataa taaaaggact aagtgtttga gatttgtctt
     5101 caaacacatg caattattcc tgagagagta cagttaggag agggttatgc cgattcgaat
     5161 tgataaaaaa ttgccagctg ttgagatttt acggacagag aatatctttg tcatggatga
     5221 tcaacgtgct gcccaccaag atatccgtcc tttgaagatt ttaattttaa atctcatgcc
     5281 acagaaaatg gtcacagaga cccagttgtt gcgccacttg gctaatacac ccctacaact
     5341 ggatattgat tttctctata tggagagcca ccgttctaaa acaactcgtt cagagcacat
     5401 ggagaccttc tataaaactt ttcctgaagt caaggatgag tattttgatg ggatgatcat
     5461 cacgggtgct ccagttgagc atttaccatt tgaggaagtg gactattggg aggaatttag
     5521 acagatgctt gagtggtcta agactcatgt ctattcgacc cttcatatct gttggggagc
     5581 tcaggctggg ctttatctgc gctatggtgt agaaaaatac cagatggaca gtaagctatc
     5641 aggtatttat cctcaggaca ccctaaaaga gggtcacctt ctatttagag gctttgatga
     5701 tagctatgta tcccctcatt cacggcacac ggagatttct aaggaagagg tcttaaacaa
     5761 gactaatctc gagattttat cagaaggacc tcaggttggg gtttctattt tggccagtcg
     5821 tgatttacga gaaatttata gttttggtca tttggagtat gaccgtgata ccttggcaaa
     5881 agagtatttt cgagatcgtg atgcaggttt cgacccacat attccagaaa attactttaa
     5941 agatgatgat gttaatcagg taccttgtct ttgttggtct tcatctgcag ccctcttttt
     6001 cagtaattgg gtaaaccatg cggtctatca ggagacgcct tttgactgga gaaagataga
     6061 agatgatgca tctgcatatg ggtatttata agaggaatta tgacatattt agacgctttt
     6121 aaatcaggta ccttggtttt accgagtgcc ctgctcttgc attttaagga actctttcct
     6181 tctagcgacg attttctggt ttggcaattt ttctatttgc aaaatacgac aggcttagaa
     6241 gaaatgtcgc caagccagat tgctgaaagg attggcaagg aaatttcgga tgtcaaccag
     6301 tccatttcta atctgacgga aaggggactg ctccagtatc gtactatcga attaaatggc
     6361 gaaattgaat tgctctttga tgctagtttg gccttggaac gtttggatga cctgtttgga
     6421 gcagttcatt caagttcaga ccagctaaca ccacaaaacc agctcaagga tttggtggaa
     6481 accttccagc aggagttggg acgattgttg acgccttttg agattgagga tttgaccaag
     6541 acactaaagg aagatggaac cagtgctgac ttgattaagg aggctcttcg tgaagctgtt
     6601 ttgaatggaa aaccaaactg gaagtacatt caggcgattt tgagaaactg gcgccatgaa
     6661 ggaatcaaga gtgtggctca aattgaggcc aagagagcag aaagagaagc aagcaatcct
     6721 cagttgacac aggtatctgc agatttcaga aatgccatgg atctctggaa ggattaatcc
     6781 atgcaagtag gcttgaaatc cgagtaagat ttgcaagctg tgtataattg tgatagaata
     6841 aatagaaaat aaattgaaaa aagaggtatg tgaaatgtca cgtaaaccat ttatcgctgg
     6901 taactggaaa atgaacaaaa atccagaaga agctaaagca ttcgttgaag cagttgcatc
     6961 aaaacttcct tcatcagatc ttgttgaagc aggtatcgct gctccagctc ttgatttgac
     7021 aactgttctt gctgttgcaa aaggctcaaa ccttaaagtt gctgctcaaa actgctactt
     7081 tgaaaatgca ggtgctttca ctggtgaaac tagcccacaa gttttgaaag aaatcggtac
     7141 tgactacgtt gttatcggtc actcagaacg ccgtgactac ttccatgaaa ctgacgaaga
     7201 tatcaacaaa aaagcaaaag caatctttgc gaacggtatg cttccaatca tctgttgtgg
     7261 tgaatcactt gaaacttacg aagctggtaa agctgctgaa ttcgtaggtg ctcaagtatc
     7321 tgctgcattg gctggattga ctgctgaaca agttgctgcc tcagttatcg cttatgagcc
     7381 aatctgggct atcggtactg gtaaatcagc ttcacaagac gatgcacaaa aaatgtgtaa
     7441 agttgttcgt gacgttgtag ctgctgactt tggtcaagaa gtcgcagaca aagttcgtgt
     7501 tcaatacggt ggttctgtta aacctgaaaa tgttgcttca tacatggctt gcccagacgt
     7561 tgacggtgcc cttgtaggtg gtgcgtcact tgaagctgaa agcttcttag ctttgcttga
     7621 ctttgtaaaa taatcagtaa gtagcaaaag ctaggtggaa cagcattcag atgtctgtta
     7681 cattttttat aggagagcaa agattgaaaa caaaaattgg attagcaagt atctgtttac
     7741 taggcttggc aactagtcat gtcgctgcaa atgaaactga agtagcaaaa acttcgcagg
     7801 atacaacgac agcttcaagt agttcagagc aaaatcagtc ttctaataaa acgcaaacga
     7861 gcgcagaagt acagactaat gctgctgccc actgggatgg ggattattat gtaaaggatg
     7921 atggttctaa agctcaaagt gaatggattt ttgacaacta ctataaggct tggttttata
     7981 ttaattcaga tggtcgttac tcgcagaatg aatggcatgg aaattactac ctgaaatcag
     8041 gtggatatat ggcccaaaac gagtggatct atgacagtaa ttacaagagt tggttttatc
     8101 tcaagtcaga tggggcttat gctcatcaag aatggcaatt gattggaaat aagtggtact
     8161 acttcaagaa gtggggttac atggctaaaa gccaatggca aggaagttat ttcttgaatg
     8221 gtcaaggagc tatgatgcaa aatgaatggc tctatgatcc agcctattct gcttattttt
     8281 atctaaaatc cgatggaact tatgctaacc aagagtggca aaaagtgggc ggcaaatggt
     8341 actatttcaa gaagtggggc tatatggctc ggaatgagtg gcaaggcaac tactatttga
     8401 ctggaagtgg tgctatggcg actgacgaag tgattatgga tggtgctcgc tatatctttg
     8461 cggcctctgg tgagctcaaa gaaaagaaag atttgaatgt cggctgggtt cacagagatg
     8521 gtaaacgcta tttctttaat aatagagaag aacaagtggg aaccgaacat gctaagaaaa
     8581 tcattgatat tagtgagcac aatggtcgta tcaatgattg gaaaaaggtt attgatgaga
     8641 acgaggtgga tggtgtcatt gttcgtctag gttatagcgg taaagaagac aaggaattgg
     8701 cgcataacat taaggagtta aaccgtctgg gaattcctta tggtgtctat ctctatacct
     8761 atgctgaaaa tgagaccgat gctgagaatg acgctaaaca gaccattgaa cttataaaga
     8821 aatacaatat gaacctgtct taccctatct attatgatgt tgagaactgg gaatatgtaa
     8881 ataagagcaa gagagctcca agtgatacag acacttgggt taaaatcatc aacaagtaca
     8941 tggacacgat gaagcaggcg ggttatcaaa atgtgtatgt ctatagctat cgtagtttat
     9001 tacagacgcg tttaaaacac ccagatattt taaaacatgt aaactgggta gcggcttata
     9061 cgaatgcttt agaatgggaa aacccttatt attcaggaga aaaaggttgg caatatacct
     9121 cttctgaata catgaaagga atccaagggc gcgtagatgt cagcgtttgg tattaagcga
     9181 tgatttgaaa gagggatgtg atagtagcac cctctttttc tttgttttat gatagttcat
     9241 cctcgagtaa attcaagatc ttgctcggaa atgaagctta tatagtagat tgaatataga
     9301 caaatacctt gtgattggta aaacatttta gaaattcatt tacctttcct aatcgacttg
     9361 gtttcatctt atttcaatct attatagtat tggggaattt cttcaaacca catcagcttg
     9421 gtcagttcta cctgcgacct caaaacttgt gctttggtca agctgggttt agtttcctag
     9481 tttgctgatg gatttccatt gactataagc atccaaccct ctttttgtct tctaaagaat
     9541 tcttaaatta tcagtctatt gcaacttttc tcatgtgggt catttggctt gcaattgtct
     9601 ttccttagta gtatactgag gtagtaatca ttaagaagtg gttacataaa aataatgaat
     9661 gaggtaaaat aaaatggtag aattgaaaaa agaagcagca aaagatgtcg caacattaac
     9721 aaaagcagcg ccagtagcat tggcaaaaac aaaggaagtt ttgaatcaag cagttgctga
     9781 tttgtatgta gctcacgttg ctttgcacca agtgcactgg tatatgcatg gtcgtggttt
     9841 ccttgtatgg catccaaaaa tggatgagta catggaagct cttgatggtc atttagatga
     9901 aatcagcgaa cgcttgatca cacttggtgg aagcccattc tctactttga cagagttcct
     9961 tcaaaacagt gaaatcgaag aagaagctgg tgaataccgt aatgttgaag aaagcttgga
    10021 acgtgttcta gctatttatc gctacctcat cactcttttc caaaaagcgt tggatgtgac
    10081 tgacgaagaa ggcgatgatg ttacaaacga tatttttgtt ggtgctaagg ctgaacttga
    10141 gaaaacagtt tggatgcttg ccgcagaact tggacaagca cctggtttgt aagaaacaag
    10201 acaacataga taaatctgta ggaaatttct tacagatttt ttctattttg taagctattc
    10261 caaaccagtc tttttttgag ttttttgata aaatagtact atcagtgaaa aggatggaag
    10321 catgactaag aaaatcgtag ctatttgggc ccaggatgaa gagggtgtga ttggtaagga
    10381 caatcgtctg ccttggcatt tgccagcaga attgcagcac tttaaagaaa caactctgaa
    10441 tcatgctatc ttgatggggc gggtaacctt tgatggaatg gggcgtcgct tgcttccaaa
    10501 acgggagacc ctgattttga cgcgtaatcc ggaagaaaag atagatgggg ttgctacttt
    10561 tcaggacgtc cagtctgttc ttgactggta tcaggctcaa gaaaagaatc tctacattat
    10621 cggtgggaag caaatttttc aggcttttga agcttacctt gatgaagtga ttgtcactca
    10681 cattcatgct cgggtggaag gagataccta tttccctgaa gagcttgact tgtctctttt
    10741 tgagacagtt tcaagcaaat tttacgccaa agatgagaag aatccttatg attttaccat
    10801 ccaataccgc aagagaaagg aagtttaatg gaacggagtt tatttggtct attcacggct
    10861 tttctgtgtt tcatctgctt tctggcagga gcacaagctt ttcgtaaaaa gcgttacggg
    10921 ctttctatcc tcctttggtt aaatgccttt accaatctgg tcaatagtat tcatgctttt
    10981 tacatgacct tattttagat agaatgacag tatagaatgg aaggaaatca tgtctacaaa
    11041 tagaaaaaat gatatgatgg tttattgctc attttgtggc aaaaaccaag aagaagtaca
    11101 aaaaataatt gctggcaaca atgcttttat ttgtaatgaa tgcgtggagt tagctcagga
    11161 aatcattcga gaagaattgg ttgaggaagt cttggcagac ttgtctgagg tgccaaaacc
    11221 aattgaactc ctccatatct tgaaccacta tgtaattggt caagatcgtg ccaagcgtgc
    11281 cttggcagtg gcggtttata accactacaa acgcatcaat ttccacgata cacgcgaaga
    11341 gtcagaagat gtggatttgc agaagtcaaa cattttgatg attggcccaa ctggttcagg
    11401 gaaaactttc cttgcccaga ccttggctaa gagcttgaat gtaccttttg ctattgcgga
    11461 tgcgacagct ctgacggagg ctggttatgt gggtgaggat gtggaaaata tactcctcaa
    11521 actcttgcag gttgctgact ttaacatcga acgtgcagag cgtggcatta tctatgtgga
    11581 tgaaattgac aagattgcca agaagagtga gaatgtgtct atcacacgtg atgtttctgg
    11641 tgaaggggtg caacaagccc ttctcaagat tatcgaggga actgttgcta gcgtaccgcc
    11701 tcaaggtgga cgcaaacatc cacaacaaga gatgattcaa gtggatacaa aaaatatcct
    11761 cttcatcgtg ggtggtgctt ttgatggtat tgaagaaatt gtcaaacaac gtctgggtga
    11821 aaaagtcatc ggatttggtc aaaacaataa ggcgattgac gaaaacagct catacatgca
    11881 agaaatcatc gctgaagaca ttcaaaaatt tggtattatc cctgagttga ttggacgctt
    11941 gcctgttttt gcggctcttg agcaattgac cgttgatgac ttggttcgca tcttgaaaga
    12001 gccaagaaat gccttggtga aacaatacca aaccttgctt tcttatgatg atgttgagtt
    12061 ggaatttgac gacgaagccc ttcaagagat tgctaataaa gcaatcgaac ggaagacagg
    12121 ggcgcgtgga cttcgctcca tcatcgaaga aaccatgcta gatgttatgt ttgaggtgcc
    12181 gagtcaggaa aatgtgaaat tggttcgcat cactaaagaa actgtcgatg gaacggataa
    12241 accgatccta gaaacagcct agaggtgact atggaactta atacacacaa tgctgaaatc
    12301 ttgctcagtg cagctaataa gtcccactat ccgcaggatg aactgccaga gattgcccta
    12361 gcagggcgtt caaatgttgg taaatccagc tttatcaaca ctatgttgaa ccgtaagaat
    12421 ctcgcccgta catcaggaaa acctggtaaa acccagctcc tgaacttttt taacattgat
    12481 gacaagatgc gctttgtgga tgtgcctggt tatggctatg ctcgtgtttc taaaaaggaa
    12541 cgtgaaaagt gggggtgcat gattgaggag tacttaacga ctcgggaaaa tctccgtgcg
    12601 gttgtcagtc tagttgacct tcgtcatgcc ccgtcagcag atgatgtgca gatgtacgaa
    12661 tttctcaagt attatgagat tccagtcatc attgtggcga ccaaggcgga caagattcct
    12721 cgtggtaaat ggaacaagca tgaatcagca atcaaaaaga aattaaactt tgacccgagt
    12781 gacgatttca tcctcttttc atctgtcagt aaggcaggga tggatgaggc ttgggatgca
    12841 atcttagaaa aattgtgagg aaaagaaaat ggcaaaaaca attcatacag ataaggcccc
    12901 aaaggctatc ggaccctatg ttcaaggaaa aatcgttggc aaccttttgt ttgctagcgg
    12961 tcaagttccc ctatcccctg aaactgggga aattgtagga gagaatatcc aagaacagac
    13021 agagcaagtc ttgaaaaaca tcggtgctat tttggcagaa gcaggaacag actttgacca
    13081 tgttgtcaaa acaacttgct tcttgagcga tatgaacgac tttgttcctt ttaatgaggt
    13141 ttaccaaacg gccttcaaag aggaattccc agctcgttca gctgtggagg tagctcgtct
    13201 tcctcgtgat gtaaaagtcg aaattgaagt catcgcagag attggataag ctagttgaag
    13261 tttggtgttg ccaaacttct tttgatataa ggagaaaaag atgacaaaga aacaacttca
    13321 cttggtgatt gtgacaggga tgagtggcgc agggaaaact gtagccattc agtccttcga
    13381 ggatctaggt tatttcacca ttgataatat gccgccagct ctcttgccta agtttttgca
    13441 gctggttgaa attaaggaag acaatcctaa gttggccttg gtagtggata tgcgtagccg
    13501 ttctttcttt tcagagattc aagctgtttt ggatgagttg gaaaatcaag atggtttgga
    13561 tttcaaaatc ctctttttgg atgcggctga taaggaattg gtcgctcgtt acaaggaaac
    13621 cagacggagt cacccactag cagcagacgg tcgtatttta gatggaatca agttggaacg
    13681 tgaactcttg gcacctttga aaaatatgag ccaaaatgtg gtggatacga ctgaactcac
    13741 tccacgtgag ctgcgtaaaa cccttgcaga gcagttttca gaccaagaac aagcccagtc
    13801 tttccgtatc gaagtcatgt ctttcggatt taaatatgga atcccgattg atgcggactt
    13861 ggtctttgat gtccgtttct tgccaaatcc ctattatcta ccagaactga gaaaccaaac
    13921 gggtgtggat gaacctgttt atgattatgt catgaaccat cctgagtcag aagactttta
    13981 tcaacattta ttggccttga ttgagccgat tctgccaagt taccaaaagg aaggtaagtc
    14041 cgttttgacc attgctatgg gatgtacggg tggacaacac cgtagtgtgg catttgctaa
    14101 acgcttggtg caggacttat ccaagaattg gtctgttaat gaagggcatc gcgacaaaga
    14161 ccgcagaaag gaaacggtaa accgttcatg agaaaaccaa agataacggt gattggtgga
    14221 gggactggaa ttcccgtcat tctaaaaagt ctgcgggaaa aagatgtgga aatcgcagct
    14281 atcgtgacgg tggcagatga tggtggttct tcaggtgaac tccgaaaaaa tatgcaacag
    14341 ttgacaccgc caggtgatct tcgtaatgtc cttgtggcca tgtcggatat gcctaagttt
    14401 tatgagaagg tctttcagta tcggttctct gaggatgccg gagcctttgc tggccatcca
    14461 ttgggaaatc tcatcattgc tggcttgtca gaaatgcagg gttcaaccta taatgccatg
    14521 cagttattga gcaaattttt ccatacaaca gggaaaattt atccttccag tgaccatcct
    14581 ttgacccttc atgcagtctt tcaggatggg acagaagtgg ctggagagag tcatattgta
    14641 gaccatcgag gcataattga caatgtctat gtgaccaatg ccctaaacga tgatacgcct
    14701 ctggccagcc gtcgagtagt gcagaccatc cttgaaagtg acatgattgt cctagggcca
    14761 ggttccctct ttacctctat tttgcccaat atcgtgatta aggaaattgg gcgggctctt
    14821 ttggaaacta aggcagaaat tgcctatgtc tgcaatatca tgacccaacg tggggagacg
    14881 gaacacttta cagatagcga ccacgtggaa gtcttgcatc gtcaccttgg tcgccctttt
    14941 atcgacactg tcttggtgaa tattgaaaaa gtgcctcagg aatacatgaa ttccaaccgt
    15001 tttgatgaat acttagtgca agtggaacac gattttgtag gtctttgtaa gcaagtttcg
    15061 cgcgtgattt catctaactt ccttcgtctg gaaaatggcg gtgccttcca cgatggagat
    15121 ttgattgtgg acgagttgat gcgcattata caggtgaaaa aatgagtttc acagtagcag
    15181 taaaagaaga aatcctgggc caacaccatc tgagccggca tgaattatct gccattatca
    15241 aaatgtctgg tagcatcggt ctctcgactt cgggcttgac tttgtcagtt gtgacagaaa
    15301 atgccaaact ggcccgtcac ctctatgagt cctttctcca tttctatgaa atcaaatctg
    15361 aaattcgtca ccaccaacgg agcaatcttc gcaagaatcg cgtctatacc gtttttacag
    15421 atgaaaaggt gcaggatttg ttaagtgatt tgcacttggc agactctttc tttggcctgg
    15481 aaacaggtat tgatgaggcg attttatcgg acgaggaagc aggtcgtgcc tatctctgtg
    15541 gcgctttctt ggcaaatggg agcattcgtg accctgagtc aggcaagtac cagttggaaa
    15601 tcagttctgt ttatctggac cacgcgcaag gaattgcctc ccttctccaa cagtttttac
    15661 tggatgccaa ggtgcttgag cgcaagaagg gggctgtgac ctatctccag cgagcagaag
    15721 acattatgga cttcttgata gtaataggag ccatgcaggc acgtgatgat tttgagcggg
    15781 ttaagatttt gcgagaaacc cgtaacgacc tcaatcgggc taataatgcc gagacagcta
    15841 atatcgctcg gacagtttct gccagcatga agaccattaa caatatcagt aaaatcaaag
    15901 atatcatggg cttagaaaat ttgccagtag atttgcagga agtggcgcaa ctgaggattc
    15961 agcacccaga ctactctatc cagcagttag cagatagtct cagcacccct ctgaccaaaa
    16021 gtggtgtcaa tcacagactc agaaaaatca ataagatagc ggatgaatta taaaaccacg
    16081 aatcctatgt gactcgtggt tcttttttat aaactggtag agtgttttgg ttgtactttt
    16141 tgttcagggt caatgtagtt gatagcgttg ttgacagcag ttggagcttc tccgaggcct
    16201 gtcgcaatca gatcaatttt tccgtcatag tagcagcagt caccgatagc atagatacct
    16261 gcttggctgg attcctgttt gctgttgacg ataatcttgt gacggttgag gtcgagcccc
    16321 cagtttttaa ggttaccgac agaagatttg aaaccatagt tgacaaagag gtggtctagg
    16381 tcaatggttt cagtttcatc agatttgact tttgtgattt caagtttatc aagtgttttt
    16441 ccatttccaa ggagttggct aggggcgaat ggtgtcttga tggttacaga tgattcttgc
    16501 aaggtttgaa cactgtgttc caaggcacgg aaattatctc tgcggtgaac aagggtagtt
    16561 ggtgcgattt tttcaaaagc caaagcccaa tccacagccg agtctccccc accaagaatc
    16621 gtcactttct taccagcgta ttgctgaatg ttagaaacgt ggtagtggat attttcatag
    16681 tcctcaaccc cttcaagttc cagcggacgt ggtttgaagg caccgccacc catagcgatg
    16741 ataactgttt tagtcaggtg acttcctttg gaagttgtga tggcaaattc ttcttcttgt
    16801 ttgtcaatct caagaaccgt ttcattgaga tgaatagggg tatcaaatcc atttagctgt
    16861 tcaatcaagc ggttagtcaa ctcttctcca gtcaggtttg ggaagcctgg tacgtctagg
    16921 atttcctttt cagggtagag aatagcaggt tgtccaccta gctggggaag agagtcgatg
    16981 atttgaacct tggcttggcg taggtgggca taaaaggctg caaaaagccc gacaggacca
    17041 ccacccacaa tggtaatatc atagagttga gacatagttt ctcctttgtt ttttctagtc
    17101 agtttatttt atcatatttt tgttcaatgt aaaatggact aggataggga aaaaaatgcc
    17161 agaaaatggt ataataggac gaaagtgttt tgatagggag gatatcaggg atgaattttc
    17221 aacaattatc caatctgcaa tattggacca gtttgtttgc aagtccatgg acgatagcta
    17281 tcaatctgat tgatattttg attgttgctt atattttata ccattttaca aaagctattg
    17341 caggaaccaa gattatgatt ttggtacgtg gagttttggt gtttatttta gctcaaatcc
    17401 ttgcaaatat gattggtttg actacgattt cttggttaat caatcaaatt attacttatg
    17461 gggttattgc ggcggttgtt atcttctctc cagagattcg gactggtttg gaacgtttgg
    17521 gaagagcgac agatttcttt tccaatgccc ctattagtgc tgaggaacag atgattcgtg
    17581 cctttgttaa gtctgttgaa tacatgagtc ctcgtaaaat cggggccttg gttgctattc
    17641 agcgtgtacg taccttgcag gagtatatgt cgacaggaat tcccttggat gctaagattt
    17701 ctgcagaact tctcattaac atttttattc ccaacactcc cctacatgac ggtgcggtga
    17761 ttatcaaaga agaacgtatc gctgtgacgt ctgcctatct gcccttgaca aaaaacacag
    17821 ggatttccaa ggaatttggg accagacacc gggcggctat cggtttatca gaagtctcag
    17881 atgccttgac ttttgtcgta tcagaggaaa cgggaggaat ttcgataacc tataatggaa
    17941 ggtttaagca caacctaaca cttgatgaat ttgaaacaga attacgtgaa atcttacttc
    18001 caaaagagga agtgggtctt agttttaaag aacgattgct aggaggatgg aaacatgaaa
    18061 aaaaatagtt tatatatcat atcctcactc ttttttgctt gtgtcttatt tgtctatgct
    18121 acggcgacga attttcaaaa cagtaccagt gctaggcagg taaaaacgga aacctatact
    18181 aatacagtaa ccaatgtccc tattgacata cgctataata gtgataagta ttttattagc
    18241 ggttttgctt cagaagtatc agtggtcttg actggtgcaa atcgcctatc gctagctagt
    18301 gaaatgcaag aaagtacacg taaattcaag gttactgctg acctaacaga tgccggtgtt
    18361 ggaacgattg aagttccttt gagcattgaa gatttaccca atgggctgac cgctgtggcg
    18421 actccgcaaa aaattacagt caagattggt aagaaggctc agaaggataa ggtaaagatt
    18481 gtaccagaga ttgaccctag tcaaattgat agtcgggtac aaattgaaaa tgtcatggtg
    18541 tcagataaag aagtgtcgat tacgagtgac caagagacat tggatagaat tgataagatt
    18601 atcgctgtct tgccaactag cgaacgcata acaggtaatt acagtggttc agtacctttg
    18661 caggcaatcg atcgcaatgg tgttgtctta ccggcagtta tcactccgtt tgatacaata
    18721 atgaaggtga ctacaaaacc agtagcacca agttcaagca catcaaattc aagtacaagc
    18781 agttcatcgg agacatcttc gtcaacgaaa gcaactagtt caaaaacgaa ttaaaaatag
    18841 aaaaggattt tataacaatg ggtaaatatt ttgggactga tggagtccgt ggagaagcta
    18901 acctagagct aacaccagaa ttagccttta aactaggacg ttttggaggc tatgttctta
    18961 gtcaacatga aacggaagcg ccgaaagtct ttgtaggacg tgacacacgt atttcagggg
    19021 aaatgctgga atcggccttg gtggcaggtc tcctttcagt agggattcac gtatacaaac
    19081 ttggtgtcct tgcaacacca gcagtagctt acttggttga aactgaagga gcaagtgccg
    19141 gtgtcatgat ttctgctagc cacaacccag cccttgataa cggaatcaag ttctttggcg
    19201 gtgatggctt caaactagat gatgaaaaag aagcagaaat tgaagccttg ctagatgctg
    19261 aggaagacac tcttcctcgt ccaagtgcag aaggcttagg aattttggta gattatccag
    19321 aaggcttgcg taagtatgaa ggataccttg tttcaactgg aactcctctt gatggaatga
    19381 aggttgcctt ggatacagct aatggagcag cttctaccag tgcccgtcaa atctttgcag
    19441 accttggtgc ccaattgacg gttatcgggg aaacaccaga cggtcttaac atcaacctta
    19501 atgttggttc aacacatcca gaagcccttc aagaagtggt caaagaaagt gggtcagcta
    19561 ttggtttggc ctttgatgga gacagtgacc gcttgattgc tgttgatgag aatggtgaca
    19621 tcgtcgatgg tgacaagatt atgtacatca tcggaaaata cctttctgaa aaaggacaat
    19681 tggctcaaaa tacaattgtg acaactgtta tgtctaacct tggtttccac aaggccttga
    19741 atcgcgaagg tattaacaag gcagttactg cagttggtga ccgctacgtt gttgaagaaa
    19801 tgagaaaatc aggttacaac cttggtggtg aacagtctgg tcacgttatc ttgatggatt
    19861 acaataccac aggtgatggt caattatcag cagttcaatt gactaaaatc atgaaggaaa
    19921 ctggtaagag cttatcagag ttggcggcag aagtaacgat ttatccacaa aaattagtta
    19981 atatccgagt ggaaaacgtc atgaaggaaa aggccatgga agtgccagct atcaaggcca
    20041 tcatcgagaa gatggaagaa gaaatggcgg ggaacggccg tatccttgtt cgtccaagtg
    20101 gaacagaacc cctcttgcgt gttatggcag aagcgcctac aacagaagaa gtagactact
    20161 atgttgatac catcacagat gtagttcgtg ctgaaattgg gattgactaa atcctagaaa
    20221 actagatgaa aataaaaaat tatggtacaa tagcttataa tattgtagcc gatggagaaa
    20281 gacatgaatc ttaaacgtga acaagaattt gttagtcagt atcattttga tgcgcgtaat
    20341 tttgaatggg aaaatgaaaa tggagctcct gaaaccaagg tggatgtgaa tttccaattg
    20401 ctccaacatg accaagaaaa tcaagtgact tccttgattg tcatcttgag ctttatgatt
    20461 gtatttgata agtttgtcat tagtggaaca atctcacaag taaaccatat cgatggccgt
    20521 attgtcaatg aaccaaatga attgaaccaa gaagaggtgg aaaccttggc tcgtccatgt
    20581 ttgaacatgc tcaatcgttt gacttacgaa gtgactgaaa ttgcattaga cttaccagga
    20641 attaatttgg agttctaata tgaaattagc tgttttcaca gattcctctg cttatctcag
    20701 tgcagagatc ttgcaaagag aagacttgtt tgtcttggat attcctgtca atattgatgg
    20761 tgaggaatat gtcgaaggca tcaatctgtc tgctgaggaa ttttaccaaa aaatggctca
    20821 ggcttctgaa ttgcctaaga ccagtcaacc aagtattgcc aagttagatg agatcttaac
    20881 ttcgctcaaa gaacaaggct atacacatgc cttggggctt ttcctatctt ctggaatttc
    20941 aggtttttac caaaatatcc agtatatggt cgatgactat gagggcttaa ccattgcttt
    21001 cccagacact ttgattacaa gtgctcccct aggcatcatg gttgaaagtg tctttaattg
    21061 gcgtgatcag ggcgatgatt ttgccagcat tcaggataag ctagccattc aaatcagccg
    21121 tacgtcagcc tttatcatgg tagatgactt ggatcatttg gtaaaaggtg gacgcctttc
    21181 aaatggggct gccattttgg gcaatttgct tagcattaag ccaatccttt attttaacga
    21241 tcaaggtgtg attgaagttt acgaaaaagt tcgtactgaa aagaaggcca ccaagcgctt
    21301 aattgaaatt atcaaggaaa caacggcttc aggtcaatac cgggtcattg tcattcatgg
    21361 gaatgctcct gaaaaggctg aagaattgcg tcagcacttg cttgattttg gcttgggttc
    21421 ggatgtttca cttgctacat ttggtagtgt cattggaacg cacctaggag caggaagtat
    21481 tgctctgggt tatattccag tgatttagtt ggcgcttcta ggctagttaa gatgccttgt
    21541 atcttagaaa ttgaacacgg actacctgcc tcttgaaaaa agatgcctgt cttgcctttc
    21601 gtggaaagtc agtgccattc cctatttttc agaggcagct aaggtccttt gtatcttgat
    21661 aattgaacac gcctggaacc ctgtgtgaaa aagatagttc ttccaagaag tagacacttc
    21721 ttgattggaa ttcctatttt cactttgtgt tcttacggac tttgtatctt agacaggagt
    21781 agagatgagt attcgagtaa ttattgccgg ttttaaggga aagatgggcc aggctgcttg
    21841 tcagatggta ttgactgatc cagacttgga cttggtggca gttttggatc cttttgagtc
    21901 tgagtcagaa tggcagggta ttcctgtttt caaggataag gctgatttag ctggttttga
    21961 agcggatgtc tgggtagatt ttactactcc agctgttgcc tacgaaaata cacgttttgc
    22021 tcttgaaaat ggctttgctc cagtagttgg aacgactggt ttcacgagtg aagaaattgc
    22081 agagctaaaa gaattttctc gtgcccaaga cttgggtggc ctgattgccc ctaactttgc
    22141 cttgggtgct gtcttactca tgcaatttgc gacgcaggct gccaaatatt tcccaaatgt
    22201 ggagattatt gagctccatc atgacaagaa aaaggatgct ccgagtggaa cagccattaa
    22261 aacagctgag ttgatggcag aggttcgaga gtccattcag caaggtgcag cagatgagga
    22321 agagctgatt gctggtgctc gtggtgctga ctttgatggt atgcgcatcc actcagttcg
    22381 tttgccaggc ttggtagctc atcaggaagt catctttggc aatcagggag aagggttgac
    22441 cctccgtcat gactcctatg atcgcatctc cttcatgaca ggagtcaatt tgggaattaa
    22501 agaagttgtc aagcgtcatg agcttgtcta tggattagaa cacttattat gagattaatg
    22561 caaatgcctt ctgaatttca gaaggcttta ccagtattag aaaaaattaa agaagcaggc
    22621 tttgaggctt attttgttgg gggctctgtt cgagatgccc ttctccatag ccctatccac
    22681 gatgtggata ttgcgacgtc ttcttatcca gaagagacca agcagatttt tccgcgaaca
    22741 gccgatatcg gaatcgagca tggaaccgtc ttggtcttag atggggatga ggagtatgag
    22801 gtaacaacct ttcggacaga ggatgtctat gtggactatc gcagacccag tgcggtttcc
    22861 tttgtgcgct cgctagaaga agacctcaaa cgccgtgatt tcacagtcaa cgcctttgcc
    22921 ttggatgaga caggagaaat cgttgacttg ttccatggtt tagaagattt ggaaaagcaa
    22981 gtcttgcgag cagttggagt ggctagtgag cgtttcaacg aagatgcttt acggattatg
    23041 cgtggtttcc gttttcaggc tagtcttggt tttgcacttg agccagaaac atttaaagct
    23101 atgaagacct tgacgccgct tttggagaaa atttctgtag agcgtacctt cgtcgagttt
    23161 gataaactct tgctggctcc attttggaga aggggcttgg cttccatgat tgagagtcaa
    23221 gcttatgact atctccctga tatggcatct agccaggaca agctcaacag actgtttgat
    23281 ttggagactg attttacttt tgaatcctct gaacaagcct gggcggcttt actatgggct
    23341 ttggagattg aaaatgcgca gtcatttttg aaatcttgga agacctcacg ccagtttgcc
    23401 aagcaagttc aggatttgct gattattttg gctctgcgtg aaaatggaga attgagtaag
    23461 cgtgattgtt atcgctttga cttggattta cttttacagg ctgaaaatct tcgtcaagct
    23521 cagggaaaag aagtcaaccc acaagtcatt aaagaaacct accagagctt gactattcat
    23581 gataagaaag aaatccaaat caacggcggt attttgatca aggaatatgg ctatcagcca
    23641 ggcccagact tgggagagat tttaacagag attgagtttg ccattgtcga tggagaattg
    23701 gagaataatc gtgaagccat ccatgcttac ctgagggaga aaaaatgagt gattttatcg
    23761 ttgaaaaact aagtaaatcc gttggtgaca agaccgtttt tagggatatt tcctttatta
    23821 tccatgactt agacagaatt ggtttaatcg gtgtcaatgg gactggcaag accacccttt
    23881 tggacgtcct ttctggtgtt tctggatttg atggggatgt cagtcctttt tcagctaaaa
    23941 atgattacca gattggttac ttgactcagg atcctgattt tgatgataga aagacagttt
    24001 tggatacggt tctatctagt gaactcaagg aaatccagct cattcgtgag tatgaattga
    24061 ttatgctcga ctatagtgag gacaagcagg cgcgtttgga acgtgtcatg gcagagatgg
    24121 actctctcca agcttgggaa attgagagtc aggtcaagac cgttcttagc aaattgggca
    24181 ttcaagactt atctactcct gttggggaat tgtcaggtgg tctgagaaga cgggtacagt
    24241 tggcacaagt cttacttggc aaccacgacc ttttgctttt ggatgagccg accaaccatc
    24301 tggatattgc gattattgag tggctgaccc tctttttgaa aaattctaag aagaccgtcc
    24361 tttttatcac tcacgatcgt tatttcttag acgctttgtc aacacggatt ttcgagttgg
    24421 agcgagcagg cttgacagaa tatcagggca attaccagga ctatgttcgc cttaaggcag
    24481 aacaggacga gcgcgatgca gctctacttc ataaaaaaga acaactctac aaacaagaac
    24541 tggcctggat gcgcagacaa ccgcaggcac gtgcgaccaa gcaacaagct cgtatcaatc
    24601 gtttccatga tctgaaaaag gaagtttcag gcagtagtgc tgagacagac ttgactatga
    24661 actttgaaac cagtcggatt gggaagaaag tcatcgagtt tcaggatgtt tcctttgcct
    24721 atgaaaataa gcccattttg caaaatttta atctcttagt tcaggctcaa gaccgtattg
    24781 gaattgttgg ggacaatggt gttggaaaat caaccctact taacctgatt gcaggaagtc
    24841 ttgagccgac agcaggacaa gttgtgattg gggaaactgt tcgcatcgcc tatttctctc
    24901 aacaaattga gggtttggat gaaagcaagc gtgtgatcaa ttacctgcag gaagtggcag
    24961 aggaggtcaa gaccagtggt ggttctacga cttccatcgc tgagttgctg gagcaattcc
    25021 tcttcccacg ttcgacgcat gggactttga ttgagaaatt gtcagggggt gagaaaaaac
    25081 gtctttatct cctcaaactg cttttggaaa aaccaaatgt tcttctttta gacgagccaa
    25141 ccaatgacct agatattgca actttgacag tcttagagaa tttcttgcaa ggttttgcag
    25201 gtcccgtttt aacagtcagt cacgaccgct atttcttgga taaggtagcg accaagattc
    25261 tcgcttttga ggatggcaag attcgtcctt tctttggtca ttacaccgac tatcttgatg
    25321 aaaaagcttt tgaaacagat atggccaatc aagtgcaaaa ggccgaaaag gaaaaagtgg
    25381 tcaaggttcg agaagacaag aaacgcatga cctaccaaga aaagcaggag tgggcaagta
    25441 ttgaaggtga tattgaaacc ttggaaaaac gtatcgctgc tattgaagag gaaatgcagg
    25501 ctaacggctc tgactttggt aagctggcta ctctccaaaa agaattggat gagaaaaatg
    25561 aagcactcct tgaaaaatac gaacgctatg agtatctcag tgaatttgat agttaagact
    25621 attcgaaaat caaagtgcaa actatgtcgg cttcacattg ccgactcaag tacagcctgt
    25681 gactggcttc ctaatttgca ctttgatttt tattgagtat aaaagaatag aaaaatcccg
    25741 tctcatgaaa ggatttctct attctttttt ggtttcttga tgaaagatat tttgccaggt
    25801 ttcgtggcga cgccagatac tggtatggat gataccatct aactcatagc agatgagttt
    25861 ggttttttga ctgatggaag taatttgaat gtccttgata gcagaattta actctttttt
    25921 ggtcttataa gcctctttat ccatctgctc tccatcttgg cgaatataga caaaatcatc
    25981 agtcaagagt tcttctagtt ggtttccttg gtcaatcaat tgttcacgca taagcaattt
    26041 tttatagaca ttgtctaaaa tttcatcctc agggataggt gctggttcga tatggacatc
    26101 ggtatcaaag acgccaaaac gctcctccag catagactcg acctgatccg cgatttcatg
    26161 gctttcaaaa acagacaagt caggattcat ctctagtgta atatccaggt agatgttgct
    26221 accgtaggtg cgacctcttt gcgatttgac cttgctgatt ttgggaattt ccatgatagc
    26281 cttttggtag tcctcgagca ggcggtcgtc aaagccatct gaaagactaa aggaagactc
    26341 gatgaagata tcataggcag tcttcaagat aaagaaagtg atgatgatag caaccagttt
    26401 atccacaatc ggataattaa aactactagc taggatggca atggcggttc caagtgaggt
    26461 aacagcgtca gaaagattgt ccttagcagc tgccttcagc gccttggagt tggatttctt
    26521 actgaggcga gtattgtaga gatagaccac aaacataatc gctgcagaaa tgattcctag
    26581 agttgcacca agaggatcaa tgaccgtttc ttcccgactg agaatctttt gaatggtatc
    26641 tcttagaaca tcgaaaccga catagaacat gatgatagaa gtgatcaagc ttgccaaatc
    26701 ttcaatcttc caatgaccaa aacggtggtc acggtctgca ggctggcgcg ccatccgaat
    26761 cccgattaag agggctacat ttccaatgat gtccgatacg ttattaaaac catcggccac
    26821 caaactggat gaatgaagga gatgaccagc tgctaatttg gctgcagaca agatcaaata
    26881 ggtcgaaata ctgataatgg ctccacgctc agctaacttg agatttgaga tagattgctt
    26941 cattcaactt cctttctagt cacatagcat tctaccatta tactggtttt caaggaaaaa
    27001 ttcaaataag gcagttttta ctctttgaaa actccccaaa atttggtata atggtactac
    27061 tcaagggagt agctggcaga aacctgtgat agtgtcgtca ttccgaattt tatgctgaaa
    27121 agtatgcttt ccggccctat cttaaacagc gagacttgtt atgattaaca ggtctctttt
    27181 tgtttgtcgt gaaaagatat gacagaaaga gagtctgttt tgcacacaat gtcaaggagg
    27241 agacacatgt caaaagaaca aaaacgccaa gcgttttata ctcagagccc tgaagaggtc
    27301 ttgcaggctg tggatgcgac cgagcaaggt ttgtcatcaa gtgaggcgga aaagcgcctt
    27361 gccgaatttg ggcacaatga actcgaagaa ggcgagaaac gatcaatctt ggtcaaattc
    27421 atcgagcaat ttaaggattt gatgattatc atcctagttg cggcagcaat cttgtcagtc
    27481 gtgacttctg gtggggaaga tatcgcagat gccattatca tcctagctgt ggttatcatc
    27541 aacgctgcct ttggtgttta ccaagaagga aaagctgaag aagctattga agccctcaaa
    27601 tccatgtcta gtccagttgc ccgcgttctt cgtgatggac acatggcaga gattgactct
    27661 aaagaattgg taccaggcga tatcgttgcc cttgaagcag gtgacgtggt accagcggac
    27721 ctacgtttga tagaagccaa ctctcttaaa attgaagaag cagccttgac aggtgaatct
    27781 gtaccagtcg aaaaagactt gtcagtcgag cttgcgacag atgctggtat tggtgaccgt
    27841 gtcaacatgg ccttccaaaa ctcaaacgta acctatggtc gtgggatggg tgttgttgtc
    27901 aatacaggta tgtacactga agttggtcat attgctggta tgcttcaaga tgcggatgag
    27961 actgatacac cactcaaaca aaatttgaac aacctttcta aggtattgac ctatgctatc
    28021 ttggtcattg cccttgttac ttttgtagtg ggtgtcttca ttcaagggaa aaatccactt
    28081 ggtgagttgt tgacttctgt tgcccttgcc gttgcagcca ttccagaagg acttcctgct
    28141 atcgttacca tcgttctttc tcttggtact caagttttgg ccaaacgaca ttccatcgtt
    28201 cgtaagttgc cagcagttga aacacttggt tcaactgaaa tcatcgcttc tgataagact
    28261 ggtacgctga ctatgaacaa gatgacagtc gaaaaagtct tctacgatgc ggttctacat
    28321 gactcagctg atgatattga actaggtctt gaaatgccac tacttcgttc agttgtcttg
    28381 gccaatgata cgaaaatcga tgtggaaggt aacttgattg gtgacccaac cgaaacagcc
    28441 tttatccaat atgccttgga caagggctat gatgtcaaag gtttcttaga gaaatatcct
    28501 cgtgtagctg aattgccatt tgactctgac cgtaagctca tgtcaacagt tcacccattg
    28561 ccagatggtc gtttccttgt agcagtcaag ggtgcgccag accaactctt aaaacgttgt
    28621 cttcttcgtg ataaggctgg ggatattgct ccgattgatg agaaggttac aaatctcatt
    28681 catacaaaca attctgaaat ggctcatcaa gccttgcgtg tccttgcagg tgcttataag
    28741 attatcgata gtattccaga aaatctcact tctgaagagc ttgaaaatga tttaattttt
    28801 actggtttga ttgggatgat tgaccctgaa cgtcctgaag ccgctgaggc tgttcgtgtg
    28861 gctaaggaag cgggaatccg tccaattatg attacaggtg accaccaaga cacagcggaa
    28921 gccattgcca aacgtttggg aatcattgac gcaaacgata cagaaggtca cgttttaact
    28981 ggtgctgaac tcaatgaact gtcagatgaa gaatttgaaa aagtcgttgg tcaatactct
    29041 gtttatgccc gtgtgtctcc agaacacaag gttcgtatcg tcaaggcttg gcaaaaacaa
    29101 ggtaaagtcg ttgccatgac aggtgatggt gtcaatgacg cgccagctct gaaaacagcc
    29161 gatatcggta tcggtatggg aatcactggt acagaagttt ctaagggggc ttctgacatg
    29221 attcttgcag atgataactt tgcgactatt atcgtcgcag tggaagaagg acgtaaggtc
    29281 ttctcaaaca ttcaaaagac tattcagtac ctactttctg ctaatactgc tgaagtatta
    29341 accatcttcc tatcaacctt gtttggttgg gatgtcttgc agccggttca tcttttgtgg
    29401 atcaacttgg taacggatac cttcccagct attgctcttg gtgttgaacc tgcggagcct
    29461 ggtgtcatga atcataaacc acgtggacgc aaggcaagct tcttctcagg tggtgttttg
    29521 agttctatca tttatcaagg tgtactccaa gcagctcttg ttatgagtgt ttatggcctt
    29581 gcgattgctt acccagttca tgtgggtgac aatcatgcta ttcatgcaga tgccctaacg
    29641 atggcctttg caacccttgg tttgattcag ctcttccatg cctacaatgt caagtctgtc
    29701 taccaatcca tcttgacagt tggcccattc aagtctaaga cctttaactg gtccatcttg
    29761 gtatccttta tccttctcat ggcaacaatc gttgtagaac cgcttgaagg aatcttccac
    29821 gtaaccaaac tagacttgtc acaatgggga attgttatgg ctggaagctt ttcaatgatt
    29881 atcatcgtcg aaatcgttaa gtttattcaa cgcaaactcg gttttgacaa aaatgcgatt
    29941 taagggaggt ttcggatgtc agcatatcaa ttaccgaccg tatggcagga tgaagctagt
    30001 aatcaaggag cttttacggg gctaaacaga ccaacagcag gtgcccgttt cgaacaaaac
    30061 ttgccaaaag gagaacaagc ttttcagctt tattcactga gaacaccaaa tggtgtgaag
    30121 gttactatct tattggaaga attactagaa gctggtttta aggaagcggc ttacgacttg
    30181 tataagattg ctatcatgga tggggatcaa ttcggatcag actttgtgaa gctcaatcca
    30241 aattccaaga ttccagcctt attggaccag tcaggtactg aagatgtaag agtctttgag
    30301 tctgctcata ttcttcttta ccttgctgag aaatttggag cctttttacc aagtaatcct
    30361 gtggaaaagg tagaagtttt gaattggcta ttctggcaag caggtgcagc accttttcta
    30421 ggtgggggat ttggacattt cttcaattat gctcctgaaa aattggaata tcctattaac
    30481 cgttttacga tggaagtgaa acgccagttg gatttattgg ataaggaatt ggctcagaaa
    30541 ccttatattg caggcaatga ctatacgatt gcagatattg ctatctggtc ttggtatgga
    30601 cagttagttc aaggaaatct ttaccaaggt tctgcaaaat tcttggatgc ctcaagttat
    30661 caaaatctag taaaatgggc agaaaaaatt gccaatcgtc cagctgttaa gcgtggcttg
    30721 gaagtaactt atacagaaat taaatagcaa aaaagtcatc ttcggatggc tttttgctac
    30781 agttgaggga aagggtttgc agttatcggc ttttgtgcta taattgctat aatatagtaa
    30841 aaagcaagag gagtgtgagg aagtggaaaa gaaaattgtg aaggatatct tatttttatc
    30901 tcaagtgtct cagccggcaa gtcaggagga cctttatctt gccagagatt tgcaggatac
    30961 actcttagca aatcgtgata cctgtgttgg tctagctgcc aatatgattg gggtgcagaa
    31021 gcgcgtgatt atctttaatc ttggcttggt tcccgtggtc atgtttaacc cagtgcttct
    31081 gtcctttgaa ggatcttatg aggcagaaga aggctgtttg tccttggtag gtgtgagatc
    31141 aactaagcgt tatgaaacca taaggcttgc ctatcgtgac agcaagtggc aggaacagac
    31201 cattaccttg acaggcttcc cagctcagat ttgccagcat gagctggatc acttggaagg
    31261 acgaattatt taggaggaaa gcaaatgaaa cgaatagtct ttgaacttat ttttatcgca
    31321 acgacctggt atatcttttt accgcccctt aacctgacca gctgggaatt tctcttcttc
    31381 ctctgtgggc atttgttagt tgtggcaatc ttatttggct ttggcaaggg gataaacctt
    31441 gtcaaaacgg ttcatgtgcg ccacggtaag gcggaagctg ccttaaatct tgagggtttc
    31501 aaaatcaatc ggttagggaa aattctgtta gcttcgattg gaggaattct tctcttggca
    31561 gctttggttt ccttggtaac ttctagcatg tttcaggcta aaaattatgc caatgtagtc
    31621 acggttacgg aaaaagactt tactgaattt cctaagagtg acaccagtaa ggttcctatc
    31681 ctagatagaa gtactgctga aaaaattgga gaccgctact tgggttccct aaccgataag
    31741 gtgtcgcaat acgtagcggc agatacctat acccaattga caattgatgg gaaaccttat
    31801 cgggtcacac cactagaata tgcagaccct atcaaatggt ttaacaatca agccaaggga
    31861 attggtgagt atatcaaggt ggacatggta actggaaatg cggatttggt ggacttgaag
    31921 acaccaatca agtattcaga ctcggagtat tttaaccgtg atgtcaaacg tcacctgcgc
    31981 ttgaagtacc cgaccaaaat ctttaaaact ccatcttttg aggtggacga tgagggcaat
    32041 cctttctatg tagcaacggt ttaccaaaag caatttggac ttgctgttcc tcgtcctgct
    32101 tcagtcatta tcttggatgc tacaaatgga gaaaccaagg aatacagctt atcagatgtt
    32161 ccagaatggg tggacaggat ctatccagca gaggaaacca ttgagcaaat taactacaac
    32221 ggcaagtaca aggacggttt cttgaatgcc atgatttcca agaaaaacgt gacccagact
    32281 accaagggct ataattactt gtctatcggt aatgacatct atctctacac aggtgtgacg
    32341 tcggctaatg cggatgagag taatcttggt ttcatccttg aaaatatgcg aacaggagaa
    32401 atcactaagt atagcttggc ttctgcgaca gaagaatcag cccgtgaatc agcagaaggt
    32461 gctgttcagg agaaatccta caaagcaacc ttcccaatcc tcatcaacct caatgacaag
    32521 cctctctaca tcatgggctt aaaggacaat gctggcttgg tcaaagagta cgccctggta
    32581 gacgcagtcg agtaccaaaa tgttatcgtt gctactacag tggaagagat gctcagcaag
    32641 tatgccaata aaaacgacct tgaaattgac aatgcaacga cagaaagcat caagggagta
    32701 gtagcagacc tcaaatcagc tgttatcaag ggcgacaccg tctacttctt taaagttgat
    32761 ggcaagattt acaaggttaa ggcctcagta tccgatgacc ttccttacct tgaaaatggt
    32821 agaaccttcg aaggtcaagt aggaaaagac agctatctca agacctttaa agtacagtaa
    32881 tactctgcga aaatctcttc aaaccacgtc aactttatct gcaacctcaa agctgtgctt
    32941 tgagcaacct gcggctagtt tcctagtttg ctctttgatt ttcattgagt ataaaaaagg
    33001 tttatttaag aaatatatgt tatagtaaaa taaattaaga ctaatggagg acaaagaaat
    33061 gggtttttat ttgatggttg cttcaatgct actcggactg ctcgctttga agataggttt
    33121 ttctcagttc aaggagaaca aagataaatt cttatctatc ttaacaagtt tagctgggct
    33181 agcccttgtt ctcgtggctg tctggttagg atggcccaaa taaatagaaa aacctcggtc
    33241 aaaccgaggt ttttcagatg aatttcttgg ttgtggctaa aaaatatgct acactatcaa
    33301 tatgaagatt ttaatcccta cagcaaaaga aatgaataca gacttgccga gtatcgagac
    33361 aactctttta agatcagaaa gtcaggctgt acttgatgcc ttggctctct attctgccag
    33421 tcaattggaa agtttctaca aggtatcagc tgagaaggct gcggaagaat gtcaaaatat
    33481 ccaagctttg aaaaggcaaa ctgctcaaca ctacccagcc ttgaagcttt ttgatgggct
    33541 tatgtaccgt catatcaaga gagacaaact gaccgaggta gaacaagcct atcttgaaaa
    33601 tcatgtcttc attacctcgg ctttgtacgg agtcgttcca gccttgtcgc ctatggcacc
    33661 tcaccgtttg gattttttga tgaaattaaa agtcgctggt aagactttga agagccattg
    33721 gaaggcagcc tatgatgaag ctgtgaagca ggaagaagtg attttctctc tcttgtcatc
    33781 agagtttgag actgtatttt ctaaggaaat cagagcaaag atggtgacct tcaaattcat
    33841 ggaggataga ggcggtcagc tgaagattca ctcaactatc tccaagaaag cgcgcggggc
    33901 ctttctaaca gctttaatag aaaatcaagt acaaactgtg ggggaagcac gtcgcttgaa
    33961 ctttgctgga tttgtttacc gagaagattt gtcacaacca cagggattgg tttttgtaaa
    34021 ggaagtatag aaatcagata agagaaaagt cagcacgatt atgctgactt ttttgataac
    34081 ttataaagta ttggacaaat gaatctcatt tgataaggtg ttaagatgat taaccaaatt
    34141 catgattgac agatgatttc ggcaaataaa cttcttggta atccctgaaa tatagaaatt
    34201 agacacgatg atatcgtaat ctgtctgatt taaaatctca ggacttgttt ttaattcatc
    34261 ccaaatatcg aaggtaaagc ggttattaca gtaataggaa agcatatcaa caaaggtaag
    34321 ggatatagca tggtcaaagt tactgataat caaaaccttg ataggtggtc gattttctaa
    34381 caactgagta gagaggtttt cagcatgggt taagatggtg tacatcaagt gttccaactg
    34441 ttcaggatgg tcatgctgtc caattgcctg acggtattga gccagttctt gacgcgcact
    34501 tcccataaag tctgggaagt aaacttcaaa ttttttaatc gtcaatgctt tttgttcaaa
    34561 taagattggg gtagaaaaga tttcctgtct ttcaaagaaa gcagtgttgt gtaaatgcca
    34621 aatcagctca tcgtggttag taaaagtaat cttatattgt tttgataggc gttctaatat
    34681 ttgactaagt aattggtaag agtatcttgc ttgactgtta tcttctaaag agttgaagaa
    34741 ttcttgagga tctaggaaaa tatcattctg aagaaaagaa ataaaaattt gagcgattgt
    34801 atctggagtc atttcaagcc caaaatgttt agagaaataa gcaagtgtct cctggaaatt
    34861 tggaatgctc tttaaaagag gataatattc tttgtaaaag tggttgggga ggtcaatgaa
    34921 gtgaccattt ttaaccctgt ggatactgat agctatcatc agtttgtaca ttctataaat
    34981 tgaaaatcgc attggataat tcgtgatttt atagaagaag tcagcaaact ctgttaaatc
    35041 ttcctcagga aggtcaggaa aaggccaatc taggaaataa tagcgctcag aaaagtattg
    35101 ggcaaaaaag taacgaatat cgatctcatt tccacgtatc tcggatggag taaaagataa
    35161 ttcaatttga aactgagatg aaagaacctt tgtaatattt ctgcccagtc gatagaggtt
    35221 ggcactacta aagtaaagat tttctattgt tcgataaata ggtagcccct cattgaagaa
    35281 catatactct agtaattgaa aagattgaga attagcaaga aaatattgat aaatatcttc
    35341 tacactagtg ttaacttcta aatctatcat gattccgtta acagaagatt ggatgttaat
    35401 agatggaaag gcaatacgta attcatttaa atcacttttt aagattcgtt ctgtacatcc
    35461 taatttttcg gctagttcat gtaatttcat ccaattacga ttctgaatta gggtttccat
    35521 taagcgtaat tgtctttgaa cttttgtgga taaaaggttt ctcatacggg tatttcctcc
    35581 ataattcatt atatcttttt ttgtctaagt agtataaaaa aattagagca agaaaattgt
    35641 cgttagtaat cggaaaaatt agaataatat aagtggcttt taagtgcaaa aacagaatat
    35701 attaattgtt cagaaaatat tgattaatgc ctcaaatagt tgtacattgt aaactataaa
    35761 atactatcta ggagtttaaa atgaaacatt cacataaaaa atcatttgac tggtatagca
    35821 tgcaacaacg ttattctatt cgtaagtatt actttggtgc agttagtgtc ttgctcggta
    35881 ccgctttggt attaggtgca gcagctagtg tccaaacagt acaagcggaa gaaaacaaac
    35941 aagaaactac caatagtatt tctgttggta ggggagaagc agctactaaa ccagcagagg
    36001 tttctgcgtc taataaagag aaaacctatg cagctccaac tgtagctaat ccagtagaaa
    36061 cgactccagt taaaactgga gaagttacta aaccagcaga aaaagttgaa gaagcaaaag
    36121 acaaaaaaga ggaagtaacg catcaagatg ctattgacaa gtcaaaattg ttaacggctc
    36181 tttcgcgtgc taaaaagtta gaaagcaagt tatatacaga agcaagtgct gctaacttgc
    36241 aaacaagtat ccaagctggt caaagcttgc ttgggaaagc agatgcatct gaagctgaat
    36301 tatcagcagc agagtcatct attcaatcat ctattattgg tctagaactt cgttctaact
    36361 ctaacaaagg aactgtatca gaaacgcctg tagcaaagaa agctaatata gttgaagcga
    36421 aggaagagac taaaccagct gtaacaacga ctgaacgttc agctgttgat agcgctattt
    36481 tgccaattag cacagctgct aaagtagaaa caacttcagc tccagcatct actaatgaaa
    36541 tcttgaaacc aagtttgagc ctttctgatg ctcgccaaaa tccagctatc cgtaaggaag
    36601 atgttgatag agggtatagt ggttttagaa cagcaggaag tggctttaga gcggctggaa
    36661 gtggttttag agcagctgga ccagaaaata aaccaatctt aaatccaaat aatactattg
    36721 cattttctga catcagtcag ggcttacatt catttcgtgg tataggacat tcacgtggtg
    36781 gtcgtgaaat ccattatgat gtaacgacag tacgtagagg taatagattg aatttcacaa
    36841 ttaaatactc tggtccaggt gaatttgtta ataataattt tatcttggat aaaggggatg
    36901 gatttggaaa tccttcaaat gcaacgatca caagttcaaa tccaagagta agggagcaat
    36961 caaaatctat tagtcagggt gccaactacg tatctcactc aggatacagt atgacctctg
    37021 ctacttcaac aaatacggaa caaactatca gatttagttt gcctatcatt aatccaaatg
    37081 gtgatttgtc tgttcgtttg aaaccagtta cttttaacgt ggaccaaggt ggtggtggtg
    37141 ccgctactag caatgaccca tacagtaact ccaactatta tcatagagca aatccactcc
    37201 tcttggatgc aaacccttat ggtggtacta ataataagac tgtttcagaa gacattgact
    37261 tccaaactgt ctatcttcca actagtaagt taccagaagg tcaaactaga ttagttcgag
    37321 aaggtgaaaa aggacaacgt caaattacct ataaagtaca tcgatttggt aacgaaacac
    37381 ttttaggatt gccaattagt aatagagtta ctaaagaagc taagccacgt attatgcaaa
    37441 ttggtgtggc taaagagtta atcgatacag taaaaccacg tgttgatcaa aataaagttg
    37501 gtgatacaaa taacctcact ttctatcttg ataacgatgg aaacggtgtt tatactgagg
    37561 gcgtagacga acttgttcaa aaaattgcta ttaaagatgg agccaagggt gaaaaaggag
    37621 accaaggtga acgcggtcta actggagcta aaggtgaaaa aggagaccga ggcgaacgcg
    37681 gtctaactgg agctcaagga gctaaaggtg aaaaaggaga ccgaggtgaa cgcggtctaa
    37741 ctggagctca aggagctaaa ggtgaaaaag gagcccgagg tgaacgcggt ctaaccggag
    37801 ctcaaggagc taaaggtgaa aaaggagacc gaggcgaac
//
LOCUS       DBEJJV010000019        36623 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.019, whole genome shotgun sequence.
ACCESSION   DBEJJV010000019 DBEJJV010000000
VERSION     DBEJJV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 36623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36623
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.019"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(299..481)
                     /locus_tag="ACL3GT_001092"
     CDS             complement(299..481)
                     /locus_tag="ACL3GT_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516769.1"
                     /translation="MNPIKAFDKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIRPEERE"
     gene            complement(483..1262)
                     /locus_tag="ACL3GT_001093"
     CDS             complement(483..1262)
                     /locus_tag="ACL3GT_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516770.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLAGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLCAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIIAGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            complement(1541..1891)
                     /gene="rbfA"
                     /locus_tag="ACL3GT_001094"
     CDS             complement(1541..1891)
                     /gene="rbfA"
                     /locus_tag="ACL3GT_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HGR0516771.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(2142..4934)
                     /gene="infB"
                     /locus_tag="ACL3GT_001095"
     CDS             complement(2142..4934)
                     /gene="infB"
                     /locus_tag="ACL3GT_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HGR0516772.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(4951..5250)
                     /locus_tag="ACL3GT_001096"
     CDS             complement(4951..5250)
                     /locus_tag="ACL3GT_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HGR0516773.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(5243..5536)
                     /locus_tag="ACL3GT_001097"
     CDS             complement(5243..5536)
                     /locus_tag="ACL3GT_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HGR0516774.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(5558..6694)
                     /gene="nusA"
                     /locus_tag="ACL3GT_001098"
     CDS             complement(5558..6694)
                     /gene="nusA"
                     /locus_tag="ACL3GT_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HGR0516775.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(6738..7217)
                     /gene="rimP"
                     /locus_tag="ACL3GT_001099"
     CDS             complement(6738..7217)
                     /gene="rimP"
                     /locus_tag="ACL3GT_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HGR0516776.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(7343..7978)
                     /gene="trmB"
                     /locus_tag="ACL3GT_001100"
     CDS             complement(7343..7978)
                     /gene="trmB"
                     /locus_tag="ACL3GT_001100"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HGR0516777.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(7975..8769)
                     /gene="ccrZ"
                     /locus_tag="ACL3GT_001101"
     CDS             complement(7975..8769)
                     /gene="ccrZ"
                     /locus_tag="ACL3GT_001101"
                     /EC_number="2.7.1.15"
                     /EC_number="2.7.1.229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0051726 - regulation of cell cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell cycle regulator CcrZ"
                     /protein_id="HGR0516778.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(8930..9541)
                     /locus_tag="ACL3GT_001102"
     CDS             complement(8930..9541)
                     /locus_tag="ACL3GT_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0516779.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            complement(9692..9925)
                     /gene="blpZ"
                     /locus_tag="ACL3GT_001103"
     CDS             complement(9692..9925)
                     /gene="blpZ"
                     /locus_tag="ACL3GT_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpZ"
                     /protein_id="HGR0516780.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(9967..10656)
                     /locus_tag="ACL3GT_001104"
     CDS             complement(9967..10656)
                     /locus_tag="ACL3GT_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0516781.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            complement(10708..11091)
                     /locus_tag="ACL3GT_001105"
     CDS             complement(10708..11091)
                     /locus_tag="ACL3GT_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HGR0516782.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            complement(11720..12039)
                     /locus_tag="ACL3GT_001106"
                     /pseudo
     CDS             complement(11720..12039)
                     /locus_tag="ACL3GT_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826248.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            complement(12559..12678)
                     /locus_tag="ACL3GT_001107"
     CDS             complement(12559..12678)
                     /locus_tag="ACL3GT_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0516783.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(12782..12931)
                     /gene="blpO"
                     /locus_tag="ACL3GT_001108"
     CDS             complement(12782..12931)
                     /gene="blpO"
                     /locus_tag="ACL3GT_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HGR0516784.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(13175..13423)
                     /gene="blpK"
                     /locus_tag="ACL3GT_001109"
     CDS             complement(13175..13423)
                     /gene="blpK"
                     /locus_tag="ACL3GT_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpK"
                     /protein_id="HGR0516785.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAVVAAL
                     GCAAGGVKYGKILGPWGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(13492..13761)
                     /gene="blpJ"
                     /locus_tag="ACL3GT_001110"
     CDS             complement(13492..13761)
                     /gene="blpJ"
                     /locus_tag="ACL3GT_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HGR0516786.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(14228..14425)
                     /gene="blpI"
                     /locus_tag="ACL3GT_001111"
     CDS             complement(14228..14425)
                     /gene="blpI"
                     /locus_tag="ACL3GT_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HGR0516787.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            14707..15294
                     /locus_tag="ACL3GT_001112"
     CDS             14707..15294
                     /locus_tag="ACL3GT_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine peptidase family C39 domain-containing
                     protein"
                     /protein_id="HGR0516788.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            15221..16864
                     /locus_tag="ACL3GT_001113"
     CDS             15221..16864
                     /locus_tag="ACL3GT_001113"
                     /inference="COORDINATES: protein motif:HMM:TIGR01193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0043214 - ABC-type bacteriocin transporter
                     activity [Evidence IEA];
                     GO_process: GO:0043213 - bacteriocin transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HGR0516789.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            16875..18236
                     /locus_tag="ACL3GT_001114"
     CDS             16875..18236
                     /locus_tag="ACL3GT_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HGR0516790.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LVASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTSPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            18293..18421
                     /gene="blpC"
                     /locus_tag="ACL3GT_001115"
     CDS             18293..18421
                     /gene="blpC"
                     /locus_tag="ACL3GT_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HGR0516791.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDLLYNINRYAHYIT"
     gene            complement(18492..19832)
                     /locus_tag="ACL3GT_001116"
     CDS             complement(18492..19832)
                     /locus_tag="ACL3GT_001116"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0516792.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLFKILL
                     AFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRKEILDKAFQK
                     SLTQINWIMGGYYLVMESLSFFEYEQSIQSKTVRHLILVFYLLFFMGVIKKLDTYLKE
                     KLYERLEQEQALRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYGSVLKDSSQKLQNNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASVEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQNQVFRQVLTVIHTE"
     gene            complement(19846..20583)
                     /locus_tag="ACL3GT_001117"
     CDS             complement(19846..20583)
                     /locus_tag="ACL3GT_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0516793.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(20588..20926)
                     /locus_tag="ACL3GT_001118"
     CDS             complement(20588..20926)
                     /locus_tag="ACL3GT_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0516794.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            21202..21531
                     /locus_tag="ACL3GT_001119"
     CDS             21202..21531
                     /locus_tag="ACL3GT_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HGR0516795.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(21699..22748)
                     /locus_tag="ACL3GT_001120"
     CDS             complement(21699..22748)
                     /locus_tag="ACL3GT_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516796.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVSGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(22745..23476)
                     /locus_tag="ACL3GT_001121"
     CDS             complement(22745..23476)
                     /locus_tag="ACL3GT_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516797.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            23544..23954
                     /locus_tag="ACL3GT_001122"
     CDS             23544..23954
                     /locus_tag="ACL3GT_001122"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0516798.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            23964..24251
                     /locus_tag="ACL3GT_001123"
     CDS             23964..24251
                     /locus_tag="ACL3GT_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516799.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            24413..24697
                     /locus_tag="ACL3GT_001124"
     CDS             24413..24697
                     /locus_tag="ACL3GT_001124"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516800.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDTTDEVSSKHCFEVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(25009..26145)
                     /gene="dnaJ"
                     /locus_tag="ACL3GT_001125"
     CDS             complement(25009..26145)
                     /gene="dnaJ"
                     /locus_tag="ACL3GT_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HGR0516801.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(26547..26903)
                     /locus_tag="ACL3GT_001126"
     CDS             complement(26547..26903)
                     /locus_tag="ACL3GT_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HGR0516802.1"
                     /translation="MSVLDEEYLKNTRKVYNDFCNQADNYRTSKDFIDNIPIEYLARY
                     REIILAEHDSCIKNDEAVRNFVTSVLLSAFVSAMVPAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(26905..28728)
                     /gene="dnaK"
                     /locus_tag="ACL3GT_001127"
     CDS             complement(26905..28728)
                     /gene="dnaK"
                     /locus_tag="ACL3GT_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HGR0516803.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(29208..29732)
                     /gene="grpE"
                     /locus_tag="ACL3GT_001128"
     CDS             complement(29208..29732)
                     /gene="grpE"
                     /locus_tag="ACL3GT_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HGR0516804.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(29759..30793)
                     /gene="hrcA"
                     /locus_tag="ACL3GT_001129"
     CDS             complement(29759..30793)
                     /gene="hrcA"
                     /locus_tag="ACL3GT_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HGR0516805.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(30957..31466)
                     /locus_tag="ACL3GT_001130"
     CDS             complement(30957..31466)
                     /locus_tag="ACL3GT_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HGR0516806.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFEQ
                     GQPDDVIYRIYDSRFLKEHKRELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCIATFLGGLVVCMSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            32074..34407
                     /gene="hsdR"
                     /locus_tag="ACL3GT_001131"
     CDS             32074..34407
                     /gene="hsdR"
                     /locus_tag="ACL3GT_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="EcoAI/FtnUII family type I restriction enzme
                     subunit R"
                     /protein_id="HGR0516807.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAMVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGEPVKVLE
                     TGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            34420..35883
                     /locus_tag="ACL3GT_001132"
     CDS             34420..35883
                     /locus_tag="ACL3GT_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0516808.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            35883..>36623
                     /locus_tag="ACL3GT_001133"
     CDS             35883..>36623
                     /locus_tag="ACL3GT_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0516809.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIE"
BASE COUNT        11449 a         7671 c         6514 g        10989 t
ORIGIN      
        1 aacatatata ctgcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaaa
       61 tgattttact gcttatatta taccatatgg agagagatta aaaaactagc agtggagttc
      121 ctgctagctc tctgcgactt ggattaccat ctagataagt ttaaagagcc aatccaatat
      181 cttaaacaat atcttgtaaa acagcaattg aactgcaaag gaaatgatca tccaaaagaa
      241 tttcacaatc ccaataatcg gtttgataaa aagaatagca agaagaccaa aaaaaatttc
      301 attctctctc ctctggccta atgagccacc gagccgtatc cattagctta tctgcaataa
      361 aaagttttcc cagaccaaca acgacatggt cagctttctt tatcgttttc atcactttta
      421 caccttgcac ggtcaaaaag taattaccat aaattttatc aaaagctttg ataggattca
      481 tattactctc ctttaatgat ttcagcctct tttcggattg tttcaacatc ttcttgatat
      541 tgaacttcac tatagttgac tagcttggat aattctttct gcaagctttc ccccattggt
      601 ttcatagttg caaaggttaa accacctgca atgataccac ccaagatagg aataaatttc
      661 cctattcctt tggccagccc tcccttggta agattcacac caaatatttt taagactttt
      721 ttcaaaatag ggtaccaaag cgtctttgtt aaagctttat taggcactgt tttcattacc
      781 tgtttggcaa ttgttatacc accagcacat agcaaagcag cggttccatt cacccctaac
      841 attacgccta gataaagcaa gagggtattt tgagcatctt cactcaactc ctcgcgtgaa
      901 gcccaaagat cctcataacc ataaatataa cctaattctt gagccaattt cagagagaaa
      961 gcataaaatt gagccacatc agctggaatg gtaattgcca tagcaagccc tccagctaat
     1021 cctgccaaaa cagaagtccc actcgctaat aatacattgt cccgaataca agcattagct
     1081 acacgatcta atatttcttg agatagaaga gtcgttgtac cttgttccaa taaggtagga
     1141 atatcttttg gatccaattc tttggaaaac ttatccacta aaaatttcga acgatcaacc
     1201 ttaacaacag gtagtttcac cacttgttgc aatacttgca tagctaagtc ttgttcagcc
     1261 atatacaaac tccttatttc ttttttacac cttatcatat tatatttcct acaaaaaaag
     1321 cattttctaa ttagataaca ttaaaaaata cagaacccct tttttatagt aaaatgaaac
     1381 aagaacagga caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag
     1441 aggcgtacta ttctagtttc aatatatttt aaaagaatat ttttccattt caaattcaac
     1501 ctattttcct ccaccaaaaa agaggggcaa cccctcttct ttagttctta tccagattgc
     1561 gtagcatctc gtcaatcttg tttccatact cgatggactc gtctttgacg aaggtcaaat
     1621 ctgggatttt gtacaatttc aaattgcgac caagttcacg tttgatggta ccagttgctt
     1681 tttcaagccc gatttgggct ttttggttat ccgaagcaag gttactcaaa atggtgtaat
     1741 aaaccttggc aacagacaag tcacccagca tctgaacatc tgtgatggtc acaccttgga
     1801 cacgtggatc acggactttc ttttgcaaaa tctcattgac ttcacgcttg atttccatgc
     1861 ccacacgatc tgtacggaaa tgatttgcca tgatattcct ttctctactt tgaaccaaaa
     1921 gctaggccag cagacctagc tattttaaac ttcttgattt tcagtttaaa ttgaaacgaa
     1981 gttcaatttg aagtcatctg cttctttcgc cgtggtgaaa gtgatggaac tgatttatca
     2041 gtcccatcac aggggatttt tgagacccta ggctcaaaaa taagcaatga aaccatcggt
     2101 ttgcttgcgt ccctcaccac ctaagaaagg agcaaaaaat cttatctctt gatttcttcc
     2161 atgacatacg cctcaatcac atcatccatc ttaatatcat tgtagccgtc gatcatcaat
     2221 ccaccttcac gaccgtttgt cacttctttc acgtcgtctt tgtagtgttt caagcttgcg
     2281 agttcgccat catagataac gacaccatca cggataacac ggactttaga gtcacgggca
     2341 accttaccgt tgataaccat aaatccaccg atagttccca ctttagacac cttgaaggtt
     2401 tcacggataa ccgcttcacc aataactttt tcttcaaatt ctggatcaag catccctttc
     2461 atagcttctt ccatctcttc gataaccttg tagataatgc tgtgaagacg gatttccaca
     2521 tcgtcagctt ctgcttgttg acgagcttgt ggtgtagggc gtacgttgaa accaacgata
     2581 aaggcatttg aagcttcggc aagggtcacg tctgattcgt tgatagcacc gaccgctgag
     2641 tggacgatag tcactttgac accttccacg tcaatctttt gaagtgaggc agaaagggct
     2701 tcaacagaac cttgtacatc agccttgatg ataacattaa cagatttgag ttccccagct
     2761 ttaagggtat caaagaggtt ttcaaggcta acacgttggg tagcttgacg ttgtttcatg
     2821 agggcacgtt tggcacgctc ttcacctgct gcacgcgcag atttttcatc ctcgtaaacg
     2881 gcaaagtggt cacccgccat cggtgcttcg ttcaaacctg tgatagagac tggtgttgat
     2941 ggtccagcaa ctttaacacg acgaccaagg tcgttggtca tagcacggac acgaccgaag
     3001 gtatttccga caacgattgg atcttgaaca ttcaaggtac cttgttgtac aagaagggtt
     3061 gcgaccgcac cttttccttt atccaagcgc gcttcgataa ccgtaccgat tgcacgcact
     3121 gttgggtctg ccttgagttc ttggatttca gctacaagaa ggactgtttc caacaattct
     3181 tcgatatttt ggttgaattt agctgagatt tcaacaaatt cagaatctcc accccaagcg
     3241 gttgacatca caccatgctc tgccaattca ccgataacgc gttctgggtt agcacctggt
     3301 ttatcaatct tgttaatagc tacgatgatt ggaacgttag ctgcttttga gtggttgatg
     3361 gcttcaatag tctgaggcat aaccccgtca tctgccgcta cgaccaagat cgtaatatcg
     3421 gtaacagaag caccacgcgc acgcattgat gtaaaggccg cgtgtcctgg tgtatcaagg
     3481 aaggtaatct tcttaccatt ttccacgatt tggtaggcac cgatatgctg agtaatacca
     3541 cctgcttcac ctgtcgcaac acgtgagtta cgaagagtat ccaaaagggt tgttttaccg
     3601 tggtcaacgt gtcccatgat agtaacaact ggtggacgct caaccaattc atcttcattg
     3661 agataaccat cttcgacaaa gaaacgttcg atgtcagcat tatccacttc aaccttttgt
     3721 ttggcttcga taccgtaatc caccatgagg agttcaattg tttccccatc caaggattgg
     3781 ttttgtgtgg ccatgacacc catcatgaaa agtttcttaa caatttcagc tggttcacgt
     3841 ttgatacgtt ttgcgatttc cgcaacggtc ataccatctg tatattcaaa ttctgttggc
     3901 aattcatgga atttacgctc cgtaacaggt tttggagtct gattacggtt gttcttgtta
     3961 ttgccttttt tgttcttttt gttgttattc cagttactat tcttttgatt tctcacttga
     4021 ttttgactac ttcgattctt ttgttgtttt ctaggaccat cttcttcatg atcataatcg
     4081 tcacgatttt tgtctggtcg agcttgtttt ttacgacgtg tatccactgc aggttctttt
     4141 ttctcaggga cgacttcaac cactgcttga acttgctgtg cttgttcagc taacttagcc
     4201 gcttcttcaa agatttcctc tggttccttg cgtttgttag cttgagccaa ggcttcttta
     4261 gcagcctgat actgcttgaa gcgttcctca cttgaacgag cgtactctgc attttgctct
     4321 gcttttaggg ctgctgcacg ggctttaaag tcaatacgtg gagccgcttg atttgaacgt
     4381 ttatcctctt gctgacggcg ctcatttcta cgtttttgct gaccttgctg cttcttagct
     4441 tggtcattaa agcgacgatt gtcgcggttg ctttgacctt gttttccacc attacggccg
     4501 tcgtttttct gacggtttcc gttttgttgt tggtcacggt tattgccctt attttgcttg
     4561 cgtcgttctg cctgctcttt agcacgggct tcacgctcag ccttgaaatt acgactttgc
     4621 ggtttcactg ctactttttc tgttttcgga gcaactggct cagccggttt tgcctcttcc
     4681 ttagctacag ctggtttagc tggctcagat ttttcggctt tcttttctgc acttactttt
     4741 ggtgctgcag gttttgcttc tactttcgga gcagctgcag gcttaaagct ggcagcaatt
     4801 tttgcagcga cagcttcttc cacacttgat gagtggcttt tcacatccaa gcccaactct
     4861 tttgcacgcg ctacaacttc tttactttct tttccaagtt cttttgcgat ttcgtacaat
     4921 cttttcttag acaaatcatg tcctcctctt ctattccata agagacctca ttttctttgt
     4981 aaatccagca tctgttacag ccaaaacctt tctcgatttc ccgactgcta tgcttaattc
     5041 cagtgttgaa aacacggtta caatttctac ttgataataa tgacttttat cttgaatctt
     5101 cttggtcaga ttgggtccag catcatgagc tagaaagacc aacttggcct tgccgtcttg
     5161 aatggccttg accaccaatt cttcacccga tatgatgcgc cctgctcgct gagcaagccc
     5221 caagagatta cttatctttt gcttattcaa gtcccaactc tcttcttttc actttgtgat
     5281 ccacataagc gatcaactcg tcataaaagc tttcttccac ttccatgcta aagctgcggt
     5341 taaagacctt cttctttttc gcctctaggg cttctgcatt gtctagtttg atataagcgc
     5401 cgcggccatt ggccttgccc gtaggatcaa taaagacttg tccttccttg ttcttgacaa
     5461 tgcggagcaa atcacgctta tcaatcactt cgttagacac aacagacttg cgcaaaggga
     5521 tttttcttgt tttcatcttt ccctcctcta gcagctttta ttcttctaca gtatcgtttt
     5581 ctacttccaa ctctactgaa gcagcgtctt ccatggcttc aaattcgcta gcagacttga
     5641 tatcgatacg gtaaccagtc aagtgagccg ccaagcgcac gttttgtcca cgacgaccaa
     5701 tggcaagaga aagcttgtta tctggaacaa ccaccaaggc acgtttgctg tcgttttcat
     5761 caaagataac ttggtcaacc tcagcaggag cgatggcatt gtagataaat tcagctggat
     5821 ctgctaccca ctcgataaca tcgatatttt cttcgattgg taccatgcgg tcatttttag
     5881 catcgtaacg agctgggtgg aatttgctag taatcttctt gatattagca ccaccacgtc
     5941 caacgattgt accgatagca tccacgtttg gattgtggct acgaacagca accttcgtac
     6001 ggtcacctgc ttcacgagcc acgctcatga tttcaacagt tccatcataa acttctggaa
     6061 tttcttgctc cattaaacgt ttgatcattt ctggatgact acggctaaca aagacgttca
     6121 caccacgagg gttgtcttca accttgtaaa cataaacttc gatacgatca tgagaagcaa
     6181 aaacttctcc aggaatttgg tcttgttttg acaattgggc ttcgatgcta ccaaggttga
     6241 catagataaa gcggttgtca aagcgttcta ctgtaccaga catgatttct tgctcatgtt
     6301 ctttgtaagt attgtaagtg atggcacgtg tttgcttgcg cattttttcc atgatggttt
     6361 gtttggcaga ctgggctgct acacgaccaa actcagctgg tgcttcttca aacttgattt
     6421 tgtctccaag ttcataagct gaattaatgg caagagcatc tttcaagctg atttccaaac
     6481 ggctatcaaa tacttcatca acaacttcac ggacagtata aactgtaaag tcacctgttt
     6541 tttcgttgaa gtcaatagct acgctgtctg actgaccata gcgtctgcga taagcggaac
     6601 gaagcgactc tactactgcg tcgatgatat cttctttttt gattcccttg tcttcttcca
     6661 aaatgcggaa ggcctctagc atttctttac tcatgttttc ttcacttttg aatcctcaaa
     6721 agctatcctt tctttttcta taatttaact gctaaacgtg cttttgatac taaactgtat
     6781 ggaatttgga cggttttctt acgcgtcttg tccatatatt ccatagtcaa ctcgtcctct
     6841 tcgaaggcca acaaggttcc ttcaaagacc ttttgcttat cgatggcttg gtagagcccg
     6901 acatggatgt attttccaac cgctccagcg acggcatcct tggttttcaa agggcgttcc
     6961 aaacctggac tggtaatttc taggaaatat tgttctggga agggatctgg cttgatggtg
     7021 tctaggacag gactgataat ttctgtcaag tctgccgtgt cgttcaaggt aattccttcg
     7081 ggtttatcta caaaaatact gagaatcatg tcactgccaa tctttccata ctcgatatcc
     7141 acgagttcaa aaggagcttc tatgacaggt tctacaactt ctctgactaa ttctacgatt
     7201 gttgcgattg cgtccacctc ctcataagca agaggcgaag atatttcccc gcctcacttt
     7261 tcatattctt actatcagta tagcacgttt gccaacttat gtaaagcaaa agcacttgta
     7321 cagcctaatt ttaggctatc tcttaaaatt ctgcctcaac tcggtagata acttgcccct
     7381 tgtttgagaa tttttgctcg tattctgtca tgacattgcc ttcaaaatca ctggcatgca
     7441 aatctaacca gacaccattg agtttcatgc catattgaga aaagctcact aaactgtact
     7501 caaacaagcc acggttatcc gtcttgaaat gaatttctcc attttcaggc aagatacgtt
     7561 tgaaggtatc caagaaggtc ttgtaggtca aacgacgctt ttcatggcgt tttttcggcc
     7621 atggatctga aaagttcaga tacaagcgat caatctcacc gtcttcaaaa tagtcagtta
     7681 agtcagaacc atctacccac aagagcttga tgttaggcac tccaacttca agcaccttgt
     7741 ccaaagcgta gctcaaaaca gacttttgaa tatcaatccc gatatagttg atgtcagggt
     7801 tttgcttggc catacctgaa acaaaggcac cctttccact tccaacttcc acatgaatgg
     7861 gattatcatt gccaaacaag tcccgccatt ttgccttggc ttccaaggga ttgaggacca
     7921 catactgggg atttgcctct agtaattctg ttgccccttt acgatttcta actctcatct
     7981 tctctttcca tacttgtctc ggaaatgacg caaaccatga atctcccgat tgacattttc
     8041 taaatcttgg ttcatataat acttggaaat ctgactcaaa taagacaatt gaccatacca
     8101 atacaattta cttaataccg tttgattgta cttgtaaccg tagtaggtca accattcctt
     8161 ccactgatgt tctgaaatat aatggcagag catatgggcc acatcaaaca tgcgatcggt
     8221 caagcgaacc gaatcccaat ctactaaata aatcaagcca ctatctgtct caatccaatt
     8281 actatgtcgt acatctccat ggacaatggt cgcatggtcc tctctaaatc ctggaatagt
     8341 ctgacgtaaa tcagccatca cttcactgat aaaatgattt ttacgcaaag catctggagc
     8401 cgtttcctgc caagactgta gtaaatctac aggtgtttcc atggcatagc ccaaacgact
     8461 caattgtgtc atcaacggac gtgagcgatg aagacgggtt aaaatattga cgatttgctt
     8521 acgattcata tcataggggg tcaatatctt gcctgtcaac cattcttgag cacacatatc
     8581 acgcccatct gccaaacgac gactccataa taattgtgga gcaatttgtt ctctagctag
     8641 accaggtagg attggagagg tgttcatttt tacaaagatg cgcttcccgt caggatagct
     8701 acccatataa gccttgccac ttttcccagg tatgggagtc agtgttagct cattatcacc
     8761 caaatccatt tctttcctcc gtataaagtt tccttactat tctactagtt tttggcctat
     8821 tcgtcaacca ctctaacccg attctcaaag aaaagcctct ggattggctt gggtatcatt
     8881 atagcttgaa aaaggtaagc accatcttct gcttaccttt tcataatttt tataaataat
     8941 ataggagtgg ccaactgttg taaaacatgt ggactagagt agaaacccat aggttttgac
     9001 tctttttata agcaaagccc agcaacaaac ccccaagtag ataaaaaata aacgaaggga
     9061 cattagaagg tccatgcatg aaagaaaaga gagaggaagt tagcacaagc cctaaccaag
     9121 aattgtcaaa aaccgcacct tgaagaagtc ctctgaaaat gagttcctcc tggatggggc
     9181 caaaaactga ggtagtcaaa atcaaagaca gggaaattcc tctgctgact tccgccaagt
     9241 gttggacccc tgagccagaa gaaacagcga agaaatgaat ataaaccagc gtctcaagta
     9301 cacttagaag aaagattgca atgaaaagca aaagttgttt cttgcttaac atcccaaaag
     9361 aaatcatttc aaactttcta gcataagcaa cactcagcga ggttacaaga agacttacaa
     9421 gaatcaatgc agattcattt tgaaaaaaac ccccatggtt aatcgtataa ggaactgtaa
     9481 tgacaattat tagtactaaa aatccaaaac acaaggcatg aaatttatca aaaaactcca
     9541 taaaactatc ctcctcacca aacagacttc ctacgcgtca ttctttagtt ctagcctttc
     9601 caaaacaaac cattttatac tcttcgaaaa tcaaattcaa accacgtcaa cgtcgccttg
     9661 ccgtactcaa gtacagcctg cggctagttt cctagtttgc tctttgattt tcattgagta
     9721 ttagtaacca aaatccgacc acatagccag cccctatgaa tatagccatt aaagctagca
     9781 tggaatttag gaaattaaaa accaccgcag atacaaaggt tagcacaaaa acattaaaag
     9841 caatggtgtc agaagccaag actagaatat agggtgtcaa ccgatctaaa gttttggaat
     9901 ctaggaaaaa taagtgttta tacatgataa tctcctctat ggctgaaaag caagcctttt
     9961 gtttttttac cccaagaccc tatgtaaaaa agtcagcaaa aatggtaatg ttgcgaaaat
    10021 attattgatc acatgcaccg cataggaagg ataaatgctc ttggtatagc gggtcaaact
    10081 agcaaagatg atgccagatg ttgcaaagat gaagatatct aacaaactag gcaggcttga
    10141 aaaatgagga agagcaaata aaattgacgg aagaagcaaa tcaaggccaa atctcgaatg
    10201 cttaaaaaag gcgtgttgca gtaatcctct atagattagc tcttccataa gtggagtcag
    10261 aaagaacaaa gttatataga tacctagctc agcaaagttg gtcccactat aaccgatcaa
    10321 tacagcccaa ccttcagcag ttgactgaac atgtttagct gtctgaacgt taaaagagat
    10381 ctggagcact accactaata ctgtcaaaat cgaataccaa agccattttt ttcttggaat
    10441 gtgaaagaga taaccatgac ctgtcttaac cagaatccaa atcatgactc cgctaaatag
    10501 caaactcaag aaattttgaa tccagacgaa attgccaatc tgggaagaaa attgccaata
    10561 attttgaata ataagcgtca tctgagaaag accaaatacg aaaaataagt aagagaaaac
    10621 tgcacttatt ttgaatagaa gttgatactt tttcatagaa atcctcccta ctatgacctc
    10681 cccttgtcag gctctactgc tgtaagatta agaagacagt ttgttttttt taaggctaac
    10741 ctgactacta gataatagat acattaaggc attaaagaca atgaaaatat gtccatagaa
    10801 taaaatcaac ctcgcatcca aaccaagata aagtttgatt atcaaaaaga tgagcaaaag
    10861 aatttgaaac cataaggttt ttccaaaaat aaatttaaag cgatttcgaa tatctacttc
    10921 cttgattttt accgccaccc ctttattagc aagaaggaaa actcctgctt caaacaaacc
    10981 actgtaaaga acaagccacc caatagatac gatagagatt tgtaaaaatg tccctaaaag
    11041 aatatccaac acactactca agaaaataac aaaaaataat ctgtatttca tattaaatac
    11101 ctccattcat ttatttcact aacaatttaa tagagccttc tactcaaata tcctgtcaga
    11161 aaaggataga aagctacttt ttataatact tcaagcccca catgagcaga agcgtgataa
    11221 acaagcagag aatacaccta tataagcgat tagttgttga tagaattctg tttctgaaat
    11281 acctctatac aaacaaatga caaacataaa atctgccaag ccgataaaca taagttgatt
    11341 ggttctagga ctaaccaaat catcatttac ttatatttaa gagtatctct tttatgttaa
    11401 tgtatgttag cactgaaaag caagacaggc caataatatt taaaatgaac agtaacgggg
    11461 ttaagtctct aaaaaaatta tctactgaca ctacaagaaa tactatacat attatagtcg
    11521 aaactatctt tttcttatcc ataattattt actcctttcc taacaaatcc aacttatcaa
    11581 tcaagagcga tttttaacat aatgtagcag cacccgttgc aactttgaca agtttagtat
    11641 atcattgttt tttaaaattt ttcatccaaa tcttgaattg tcatcgaaac ctcctaaatt
    11701 gcaaaaactt cattagcccc tactttttat aatacttcaa accccaaatg agtagaagca
    11761 tgatgatcaa gcaaagaata gcaccaatat aagcgattag ttgttgataa gattctcctg
    11821 ctgtgatacc tctatacaaa caaataatag acataaagcc tgtcaagccg ataaacatga
    11881 gttgattggt tctaggacta accaaatcat catcttcaaa ctctcttaat ctcatttccc
    11941 tagtaagata aacagtaacc aaaatagaag tcaagttaat aactactaaa agaaattgga
    12001 aaactgacga aatagaaata gataagtaga aacaagcaaa ggcaactgac ccaggaacaa
    12061 tctcacaaag aatatgattc tttttaatca agaaaatctt tcatttcttt tctttctttt
    12121 taattaaaga aaaatagatc ataaccgcaa tcatataggc tatggtataa aatagattat
    12181 accaaatact ctccctaagc ggataaagaa agatggacat gatcagatac agaacgaaaa
    12241 taatcagtat ttttttcttc ataagttttc ctcctaaatg tgcgatttat cttagttgag
    12301 caagaacatt tacactgcta gtatagcact tattttgacc ttggatcact caaatcataa
    12361 atggtcatca aaacctcttg aattgtaaaa attaaaaaag caagcatgaa aaacatactt
    12421 tcctctttat attgtattga taccaacttg tttgtagact tttcatcctg ctatcacata
    12481 tcattttgac aggcgaaaca atattaaaga aactcccctg taaattaagc tagcaaatac
    12541 aggggagaaa tttatttttt agagagtact atccgtatcc tttttggaag attttgaaaa
    12601 tatttttcta attaagtcat ccatataagg accaaatata ccaactacta aaccaataat
    12661 aaaactttta aaatccataa ttaccaccaa catgttgctg cataggctac acctccaagt
    12721 atagctccac ctgcagcacc agttacacct attcctatag caaatggtcc caatagaaat
    12781 gtcaaaccgt tgttgcacac ccatcaattg cgccatatgc aacccctgct gcacaactaa
    12841 tttttcttcc ccaatcaata tctccacctt caacgcaagc aagcatttca ttatccataa
    12901 cagaaaattg tgacatcatt tttgtattca tatagtatgt cacttttcag ttacggaaca
    12961 agtttaatat aaaaattatc aaaaaaacat aggcaataaa gagaaaaatt aatttatcat
    13021 agattagaaa taatatgaca aaacaattca atgatgttaa ttcaatagtc ttttgttttt
    13081 tatcagagat acttatggat agataaataa gataggtttg aaaagcgaag agaataataa
    13141 agaatatagc cttcataaaa tttagctttc atttttatga tgtagcggta taggctaaat
    13201 atccacaaac cactgctcct ccaattcctc ctattgcagc gccccatggt cctagaattt
    13261 tcccatattt cactccaccc gctgcacaac ctaaagcagc aactacagct gctcctccaa
    13321 cacctgcttt ggcaaaatct ccccaattgc atccgccacc ttcaacgcaa gcaagcattt
    13381 cagtatccat aacagaaaat tgtgacatca tttttgtatc catgacaaat actccttttt
    13441 taaaaaacta aaataaatca gaatagaatc ctcataattt tactataagt cttaccaact
    13501 tagtcccaat ttatcaccaa ccatacctcc taagcatgtt aatccacccc caattgcacc
    13561 aatgtgtgct ccaacaaatg caccagcaag tccagctact cctaaagtgg ccaaacctgc
    13621 tccagttcca ccagttataa ttcccgtagt gactcctgta atcagtgcat tttgacaatc
    13681 agtggagcta tacccccctt caactttcgc aagcatttca gtatccataa cctctaactg
    13741 tgacaacatt tttgtattca tgatgaatac ctccttttta ttttcaattt gttaccaaag
    13801 tcttaaattc aataaacaaa tagatttttt ttagtatctt tttgattttc ttaaaaaagt
    13861 atatacgtct actatcttct taaaggtagc agtacctatt ttttagtcta agatttcaat
    13921 aatcttgagt atctaaaata tcttaatttc gttattctcc ttgcaataaa aagttttact
    13981 atactattta ttaacttgca gaaagcaaaa aatattagta aataatagtt tatagttaag
    14041 ttttttattc ctaccaatcc atcaactaag taaagcatca acgattacat aaacgattga
    14101 taatataatt aaaattttgc taactatctt attctcatga ttcttagata actttgatat
    14161 tttgtaagta agtaaataag acagtaaatt aatagcgata ataatactat atttaagaat
    14221 cataatctta caaagaggac ataattcctg aacctacaca aataagtgtt gctgctcccc
    14281 cagttatcgg accagtcgca gcagctaata gtactgctcc aatacaacca ccgattgcag
    14341 atcctaaatt gcctcttcct ccactaacta tttcgagttc ttcattatcc ataacagaaa
    14401 attgttccat catttttgta ttcatgacaa atactccttt tttctttttt tatttttgtc
    14461 ttgttgtaac tttgataagt ttagtatatc atcgtttttt aaaatttttc atccagatct
    14521 tgaattgtca tcgaaacgtc ttgaattagg ttttttattt caagccacct ctaaatgttt
    14581 aaaaaaaata atttctaatc acttttttac cattcaggaa gttttaatga ctattcaaga
    14641 tttcataaaa tatgaactta gttttatgac ataatagacc tatccactat atgaaaggaa
    14701 ttgccaatga cttcttataa acgtacattt gttcctcaaa tagatgcgag agactgtggt
    14761 gtcgctgcct tagcctcgat tgctaaattc tatggttcag atttttctct agctcacttg
    14821 agagaacttg caaagaccaa taaagaaggg acgactgctc ttggcattgt aaaagccgct
    14881 gatgaaatgg gctttgaaac aagacctgtt caagcagata aaacgctctt tgacatgagt
    14941 gatgtcccct atccatttat cgttcacgtt aacaaagaag gaaaactcca acattactat
    15001 gttgtctatc aaacaaagaa agactatctg attattggtg atcctgaccc ttctgtaaaa
    15061 atcactaaaa tgtcaaaaga acgctttttc tatgaatgga ctggagtagc tatttttcta
    15121 gctaccaaac ccagctatca accccataaa gataaaaaga atggtctact aagcaagctt
    15181 ccttcctctg attttcaaac aaaaatctct cattgcttac attgttctct caagcttatt
    15241 ggtcactatt atcaatatag gtggttctta ctatctccaa ggaatcttgg atgaatacat
    15301 tccaaatcag atgaaatcaa ctttaggaat catctcagtt ggtctggtta tcacctatat
    15361 cctccaacaa gtcatgagct tctccagaga ttatctccta accgttctga gtcagagatt
    15421 aagtattgat gtgattttat cctatattcg ccatattttt gaacttccca tgtctttctt
    15481 tgcgacacgt cgtacaggag aaatcatttc acgattcaca gatgctaact ctattataga
    15541 tgccttggct tctaccattc tttctctttt tctggatgtt tctattctga ttcttgtagg
    15601 aggcgtctta ctggcacaaa accctaatct cttccttctt tctcttattt ccattcctat
    15661 atacatgttc atcatctttt cttttatgaa acctttcgaa aaaatgaacc atgatgtcat
    15721 gcaaagtaat tctatggtta gctctgccat tatcgaagat atcaacggga ttgaaactat
    15781 aaagtcgctc acgagtgaag aaaatcgcta tcaaaatata gacagcgaat ttgtagatta
    15841 tttggaaaaa tcctttaagc tcagtaaata ttctatttta caaacgagtt taaagcaggg
    15901 aacaaaatta gttctgaata tccttatcct atggtttggc gctcaattag tcatgtcgag
    15961 taaaatttct atcggtcagc tgattacctt taacacactt ttttcttact ttacaactcc
    16021 tatggaaaat attatcaacc tccaaaccaa actccaatct gcgaaggtcg ctaataaccg
    16081 tttgaacgaa gtctatctag tcgaatctga atttcaagtt caagaaaacc ctgtccattc
    16141 acattttttg atgggcgata ttgaatttga tgacctttct tataagtatg gttttggacg
    16201 agatacctta acagatatta atctcacgat taaacaagga gataaggtta gcctagttgg
    16261 agttagtggt tctggtaaaa caactttagc caaaatgatt gtcaatttct ttgaacccta
    16321 caaaggacat atttctatca atcatcagga tattaaaaac attgataaaa aagtcttgcg
    16381 ccgtcatatt aattacctac cacaacaagc ctatatcttt aatggctcta tcttggaaaa
    16441 cttaactttg ggcggtaatc atatgattag ccaagaagat attctaagag cttgtgaatt
    16501 agctgaaatt cgtcaagaca ttgaaagaat gcctatgggc tatcaaactc agctctctga
    16561 tggagctggt ctatcaggag gacaaaagca acgaatagcc ctcgctcgtg ctcttttaac
    16621 taaagctcct gttttaatac tagacgaagc tactagcggt cttgatgtct tgactgagaa
    16681 aaaggttata gataatctta tgtctctaac tgataaaacc attctctttg tagcccatcg
    16741 tctcagtata gccgaacgaa ccaaccgtgt cattgttctt gaccagggga aaatcattga
    16801 agttggtagt caccaagagt taatgcaggc gcaaggtttc taccatcatc tattcaataa
    16861 ataaggagaa tgtcatgaat cctaatcttt ttagaagcgt cgagttttat cagagacgtt
    16921 accataacta tgcgacagtg ttcattatac ctctttcatt actatttact ttcatcttga
    16981 ttttctccct tgttgccaca aaagaaatta ctgttacttc ccaaggagaa atcgccccta
    17041 caagtgtcat tgcctccatt cagtcaacca gtgataatcc tatcctagct aatcatttag
    17101 tggcaaatca agtagttgaa aaaggggact tactcatcaa atactctgaa acaatggaag
    17161 aaagtcagaa aactgcctta gcaactcaat tacaaagact tgagaagcaa aaagaaggac
    17221 ttggaatttt gaaacaaagc ttagaaaaag cgactgatct tttttctggc gaggatgaat
    17281 ttggctacca taataccttt atgaatttta ctaaacaatc ccatgatatt gaactgggta
    17341 tcacaaagac taacaccgaa gtttcaaatc aagctaatct ttccaatagc agttcatcag
    17401 ctattgaaca agaaattaca aaagttcaac aacaaattgg agaatatcaa gagttgagag
    17461 atgctatcat aaataacaga gcacgcttac caactggcaa tccgcaccag tcaattttga
    17521 atcgttatct tgtagcctca caaggacaaa cacaaggaac tgcagaggag ccatttttat
    17581 ctcaaattaa tcaaagtatt gcaggtcttg aatcatctat cgcaagcctc aaaattcagc
    17641 aagctggtat cggaagtgta gcaacttatg ataacagttt agcaaccaaa attgaagtac
    17701 tccgcactca gtttttacag acagcctcac agcaacaact aactgtggag aatcaattaa
    17761 cagaattaaa agtacaacta gatcaagcca cacagcgttt ggaaaacaat accttaacct
    17821 ccccaagtaa aggtatcgtt catctgaaca gcgaatttga aggtaaaaat agaattccaa
    17881 ctggtacaga aattgctcaa atattccctg tcatcacaga tacaagagaa gtactaatca
    17941 cttactacgt atcttctgac tatctacctc tactagataa aggacaaact gtaagattaa
    18001 aactggagaa gattggaaat cacggcacca ccatcatcgg ccaacttcag acaattgatc
    18061 aaactcctac cagaacagag caaggaaatc tctttaaatt aaccgctctt gcaaaactat
    18121 ctaacgagga tagtaaactc atccaatatg gcttacaagg tcgcgtcact agtgtaacta
    18181 caaagaaaac atattttgat tatttcaaag ataaaatttt aacccattct gattaatttt
    18241 cagataacac tctataacta tttattatct tatcaaaaag gagaatcata acatggataa
    18301 gaaacaaaac ctaacttcat ttcaagaact aacaactacc gaactcaacc aaattacagg
    18361 tggaggattg tgggaagatt tattatataa cattaataga tatgctcatt acatcacata
    18421 agaacttcat catccaatac aactataaaa aaataagacc gagaaacaag tactctcggt
    18481 cttatttttc atcattctgt atgtatcaca gtaagtacct gacgaaagac ttgattttga
    18541 caggtggtat ttagactggt attaggatgg ctttccacaa tcttcatgac ggtatagaga
    18601 ccaactcctc tctcctcccc tttagaactg gctccaaagg agaagatttc agaaatatcg
    18661 atgccctctt ctttgatgga gttttcgatg ataaaggtct cctgtgctcc attttttaaa
    18721 aaggcgattg aaacatgagg ttgactagct tccacactgg cttcaatagc attgtcacaa
    18781 aggatagaca caatggttag aaaatcaagt agactcatcc cctcgacctg aatctcctca
    18841 ggaacttcga cattaaagac aatgttctta tctctggctt ttaaaaattt ccctgctaga
    18901 agacttttga gggctttatc acgaatattt accaatctgc ccaggtcata tttattgttc
    18961 tgcaatttct gactggaatc ctttaagacg gagccataga cctcttttat ctgctccata
    19021 tcctcctctt caatgcccag acgtaagcta gtcaagaggt tggtataatc atgacgaaag
    19081 ctccgtactt ccttgtaaag ctcctctata tgccgactat agcgttccat atctctatag
    19141 cgcagggcct gctcttgttc caatctctca tagagttttt ccttcaaata ggtatccaat
    19201 ttcttgataa cccccataaa aaagagtagg taaaagacta ggatgagatg gcgaacagtc
    19261 tttgattgaa tactttgttc atattcaaaa aaagacagac tttccatgac tagatagtag
    19321 ccacccatta tccagttaat ctgagtcagg gacttttgaa aggctttatc gagaatctcc
    19381 tttctcaagc tagtaaaatc gtagtccaac catttcaaaa aagctagaga aatgaagaaa
    19441 ttgaaaatta ttatacataa cccagtaaat gagtagccat catatacttg cccttgtccc
    19501 aaaaatggaa gcacaaaata ggagactcct ctataaaaga gattcaccaa tatcattgga
    19561 aagagaccat aaaagaaaag gagtttttta ggaagccctc tcaataataa gaaagataag
    19621 cctatgccgt acaagggttc cataaaataa gataggtaaa catttcctac tatatagcta
    19681 atcatcacaa aaacaaaggc caacagtatc ttaaaaagaa aggccttaaa aatcctctcg
    19741 aaagtaagat caattccatc caccttaaag aagatgacaa tttctagtcc attagtaaca
    19801 agtgtataca acaatatcca agcaatgttc ataaattctc ctagctcagt gtaatttatt
    19861 gatggcctca gacacttccc tgaccttata acgggcgatt agacaacttc caccattggg
    19921 aaagaaaagc agtttttctt tcttatccaa atgcaccaca tttgcaggat tgatgagaaa
    19981 agagcggtgg cactgcaaga gacggggctc ctgcttgaaa acctcctcta aactcgctgt
    20041 aaattccagc ctgtctgtct tggtatagag aataacacga tgggctctgg gcgacgtttc
    20101 gagatagtaa acctctttaa aaggatactg aaattgggca aattttgatt taaagtaaaa
    20161 gcaatcttcc gccagacttt tactatcttg actattggca tagaggaggg ctgtctcgat
    20221 ccgagattca aactcctctg ctgacaaggc cttatcaatg tagtccaaag cagacacttg
    20281 gtagcgaaaa gacaggggca taaactccga gtgagtcgtc acaaagacaa tcagggcata
    20341 aggatcccga tcccgaatct ttctagccac ttccagtccc ttcatctctt catttcgaat
    20401 ctcaatatcc aaaaagaata gctgatgggc ccccttctca tgcacttcag ccagcagttg
    20461 gtccggcttg ccaaatacct caaaagagct aggaatgata tgatgtgctt tcaaaagttt
    20521 ctcaatcgtc gtttcaattc tagtctgttg ggaaaaatca tcctctaaaa caaatattct
    20581 catcttctta ctctccctct ttcaaccatt tttgacgaat ttctctatag cgacgtctgg
    20641 catacttgac agcgtattga ccttcttctc cgagaaaaag gattctttct tgaaaatcaa
    20701 tcgattttaa tttatcaaga ttaaccaaac aatttcgatg acatctcatc aaggtttccc
    20761 cacattggtt ctcaagatta cttaaatttt gaagcatatt aaaactagct tcttctgtaa
    20821 caatctgtac ggtatgggct ttagttggat gtgtttggat atagtagata tcgtcgatgt
    20881 ttactttata gactgttttc tgcgtctgaa taatcatata tttcattgga ttctcctcct
    20941 aagaaaagaa taacagaaaa ggtctagccc aagcacaccc aatcctaaac agtctttgaa
    21001 aactcctaaa aggattattt tctacaacat catgatgagc ttacaactat tttatcataa
    21061 aattcactca gcgcaattca agacatttca atgacaatta aagatttgaa taaaaaaaaa
    21121 gaattaaaag tgataaacta acagtatcaa aacacagttg ccagaagtaa gactggcacc
    21181 cagattaaag gaggcattcc catgacagat acagacccca tcaaaagagc tcatactttg
    21241 attactgact taaacaaagc ctaccaagca tgcaaacagg caagcgctga cgacgtccgc
    21301 tttcaggagc aattaaactc tattcttggt tttctagcca aggctgaaac agtggataat
    21361 cgattcttga ttgaactaga aaaattttac cagacttcca gtcttctcat gggactcagc
    21421 gctcttgatc cagatgctcc aactcgcgcc gcttggcggg cctatgaccg cttccacttt
    21481 gaccaagtca agaccaagtt aatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    21541 cgcaagctgt acttgagtac ggtaagacga cgctgacgtg gtttgaagag attttcgaag
    21601 agtataagtc tctacggacc aaccattatc ctgtagtaac aaaaaagaag ttgagacaga
    21661 ctgaactcaa cttctttttt agtgtcgtat cagcaatgtt agtcctgcat ctgacgtttt
    21721 acctgataag gcaaatacaa gactagtaaa accaaaccag ctcctagtaa ggctagaagg
    21781 gctagttttt cttggaaggt aatcaaccca acaactaatt ccacaagtaa aacaaaactg
    21841 gtcaatcctc gaactacctc ctgtaagcct ttttcctttt gccccttgtc cagcggaaag
    21901 agttgggtca aatactggta gtcaaaggca tgatagaggg ccagcaactg gaagagcaag
    21961 aggtagttaa agagaactac cactgctgtc gcaatccaag cttgctcgat aaaaacctgc
    22021 gccagtacgg aaagtaagag aagacgaaga ctgagagcaa agaggtcgcc atttcgcaga
    22081 taagaacgca gatagagatt ttgccaaatc tttccagaca ccttctgaac agcctttaag
    22141 ataaagtcca gataggcacg acgtttgaca ctgtttgaaa ttccctttac ctgcgtaaag
    22201 agggcaaaga aacgaagcaa gacttgctta cgcttgcttt cttgggaaat gacatagtcc
    22261 cagtccagcc cagtttcagt gaaaaatttg ctggcctttt gacgaaagtg gaaatatttt
    22321 cctaccccca ataaaagcac atagagcaga aaaactggca agccataacc cattgctaaa
    22381 aataaaggcg caaataacag caagaaaagg gtctgtacaa agagccaaaa gactagggaa
    22441 atgccagttt gacgcttgag atggagcttg atttcctctt ctccaactaa gagaaagagc
    22501 ttgtctggag cctccatata ggtggcaatt cctccccaaa gtaaaagtaa aacagacgta
    22561 attcctacaa acaaaaggat aggccaatga ttttcaggaa aatgttgtaa gagttgactg
    22621 tactggtagg ctagaaagcc caacaggaca agcaggaaca agacaaagtg gtcattgagc
    22681 acatagcgca gataaccaag gcactcctta cgaaaggcct gctttctctt taaaaacaag
    22741 tctttcatag atcctcctct ttggtcagag ccaagtaaat atcattcaaa ctagcctcag
    22801 gcatatcaaa ggcttcacgt agttgcagga gattgccttt ggcacgcacc tctcccttgt
    22861 gaagaatgac aaaggcatca cacatcttct ccgccgaatc cagcacgtgg gtactcatga
    22921 gaatagactt gcccttttgc ttctccactt ccaaaagctg aatcaaatca gaaatagcca
    22981 gcggatcaag accaaggaaa ggctcatcca cgatgaaaag acttggatcc accacaaaag
    23041 cacagataat catgaccttc tgcttcatcc cttttgaaaa atgaacaggg aaccagtcta
    23101 atttctgttc caaacggaac atttttaaca agggctctac tcgttcgaaa gccacttttt
    23161 gctcaatacc gtaagccata gcaaccgttt cgatatgctc tctgagggtc aattcctcat
    23221 acagactagg cgtctcagga atgtagccaa tctgcttgcg gtagctagtc gcatctcctt
    23281 gcagagtcag gccattgata ttgatggagc cactataagg tgccaacaga ccgataatct
    23341 cattgatcgt cgttgatttc ccagcaccat tgagaccaat caaaccgacc aactgcccac
    23401 tttcaacagt aaaggacaca tctttcaaaa cagggacatg aacatagcca cctgtcaggt
    23461 ttttaatttc taacatattt tctccaaatc tggtataatg tagctatatt atatcaaaat
    23521 tcagtacagt agaggtagat tttatgtcag attgcatttt ttgtaaaatc atcgcagggg
    23581 aaattcctgc ttcaaaagta tatgaagatg agcaggtcct tgcctttctt gatatctctc
    23641 aagtaacact aggacacacc ttggtcgtgc caaaagaaca ctatcgcaat cttttggaga
    23701 tggatgctac gagcgccagc caactctttg cccaagtacc aaaagtagct caaaaagtca
    23761 tgaaagtcac taaggctgct ggtatgaata tcatttccaa ctgtgaagaa gtcgctggtc
    23821 aaacagtttt tcatactcac gttcaccttg tacctcgcta cagtgctgac gatgacctca
    23881 agattgattt tatcgcccac gaaccagact ttgacaaact tgctcaagtc gctgaaacca
    23941 tcaaaaacgc ttaaggagtt gctatgaaat tatccaacct actgctattt gcaggagctg
    24001 cagccggaag ttatctggtc acaaaaaatc gccaaaccat cacagatgaa gtcttgaata
    24061 ccactgaccg cgttcaagct atcaaggacg atgtggatat tatccaaaac agcctgcaaa
    24121 tcattgacca gcaaaaagaa cttatcaagg aataccaaga agacttgact tacaagttta
    24181 aggtcttgga aaaggatatc cagactagac tagctgtgat aaaagaaatg cagggaactg
    24241 aagataagta aaaagagccc cccggctctt ttttaaaacg taaacaagtt atagtgaatt
    24301 gaatttagaa tagcacatca tagtttctaa agcattgtta gagattactt taaaatcctc
    24361 ttatcaattt gttcatattc tatttcaatc tactatatat atcccatcaa ctatgcatca
    24421 taatttaggt aactcatact caataaaaat caaaaagcaa actagaaagc taggcacaga
    24481 ctgctcaaaa caccgtttta aggttgtgga tagaactgac gaagtcagct caaaacactg
    24541 ttttgaggtt gtagatacga ctgacgaagt cagctcaaaa cactgttttg aggttgtgga
    24601 tagaactgac gaagtcagta accataccca tgacaagccg acgctgacgt ggtttgaaga
    24661 aatttttgaa gagtatcatt caccatttca caactaaatc gaagactttc tgccgtaatg
    24721 aaaacacctg aaacagcttg gtttcggctg tccggaaact ttaagactta ggttcaaagt
    24781 ttaggtatgg aacttcgaag gaggtcgcta ccgtccgtca ttacttagga aagtcttaaa
    24841 aaatcggctc tataaagtaa aaagagcccg acagctcttt ttgtttatat tcaatgaaaa
    24901 tcaaaaagca aactaggaaa ctagccacgg gctgctcaaa acactgtttt gaggttgtag
    24961 atacgacaag ccgacgctga cgtggtttga agaaattttt gaagagtatt attctccatc
    25021 aaaggcatct ttaatatggt caaagaagcc ttttttcttt ggatttactt tcaagtcacc
    25081 agcagccgcg aattctttca aggctacttt ttggcggtcg ttcaagcctg tcggtgttac
    25141 gacattaaca gtaacgtatt ggtcaccaac tgcaccgcca cgaaggctcg gtgccccctt
    25201 actacgtagg cggaatttct taccagtctg agttccctct ggaataacca attcaacatc
    25261 accgtgaaca gttggaatat ctactgtatc accaagagcc gcttggacaa agttgaggtt
    25321 gagattgtag aagatagtcg ttccttcacg ttcaaacttg tcgctagctt ctacagaaac
    25381 tactacatac aagtcaccat aaggtccacc gttaaagcct gcttcacctt gaccagcgag
    25441 gcgaatttgt tgacctgttt ccacaccagc agggattttc acatgtacgc tatgagcttg
    25501 tttctcatga cctgttccat gacaggttgt acatggatat ttgatttctt ttcctcgacc
    25561 gtgacagaca tcacaggtta cttggcgacg catcatacca agaggagtct gcgtatcgac
    25621 gttaatgaca ccagcgccat gacagcgtcc acaagtgact ggacttgtcc ctggcttagc
    25681 accagagcca ttacatgtac gacagccagc ttcacgatga tacttaactt ccttctcagt
    25741 tccgaagata gcttcttcaa aggtcaaatt gacacgatac tggagatcat ctccttggcg
    25801 aggagcgttt ggattgcgcg aagaaccgcc tccgccgaag aaacttgaga aaatatcctc
    25861 aaaaccaccg aaaccacctg ccccattgaa accgccgaaa ccaccagctc caccaaaacc
    25921 accattggcg cctgcagcac catactggtc ataggcagca cgtttttggt cgtcactcaa
    25981 agtctcatag gcttcttgaa cttccttgta cttgtcctca gcaccaggct ccttgttgat
    26041 atctgggtga tattttttgg aaagcttacg ataagccttt ttgatttcgt ctgccgaagc
    26101 gtttttggat acccccagac gatcataaaa ttcagtattg ttcataattc aagatacaaa
    26161 gggcgtcaaa cggacacagc catctaggag ttttgacgac ggacgcttac gtcctagaaa
    26221 aaactatctt ttgggcacag tccgtagccc gtgttcagtt acgaacaccc ttattccttt
    26281 ctattgatgt tctgaatcga accaccattt aggtcgggtt caattccttt cttttatatt
    26341 tagtaagaaa ttctgaaacc cgtgttcagt tacgaacact ctttgttccc ttctattgat
    26401 gagacaaaac ccaaacaaat gagattccgt ccctttttat cgaaaaacag aggctgggtt
    26461 gcaacctctg caaataagta aattaacttt attttgattt taaatatcct ataagtacag
    26521 aaatatttat atatttttgt ctcttcttag tatttgccta tataattcca attgatcata
    26581 agaaatacaa ctactgtcca aatcatacca attatgaacg gtattacaaa tttatatgtt
    26641 tgtatttcta atgatatcat agctggtacc atcgccgata caaatgcaga caacaatact
    26701 gaggtaacaa aattccttac cgcttcatca tttttgatac aactatcatg ttcagctaat
    26761 ataatttctc tatatctagc taaatattct attggaatat tatcaataaa atcttttgat
    26821 gttctatagt tatcagcttg attacaaaaa tcattataaa cttttcgtgt attttttaga
    26881 tactcttcat ccaatacact catcttactt ttccgtaaac tctccgtcta cgacgtcatc
    26941 gcctgcgttc cctgttgctt gtgcgccttc tgctccttct tgagcttgtt gcgctgctgc
    27001 ggcttgttcg tagagtttaa cagcaagtcc ttgagctttt tcgttcaatg cttcaagttt
    27061 tgttttcatg tcgtccaagt tgttgtcttc ttgagctttc ttaaggtcat caagggcagc
    27121 ttgggcagcg tcacgttctg cgtcgaagcc tttaccttca gtttccttga ttgtcttttc
    27181 agtcgcaaag attgcttggt ctacttcatt acgaaggtct acttcttctt tacgtttctt
    27241 atcggcttca gcgtttgctt ctgcatcttt catcatgcgg tcgatttctt cgtcagtcaa
    27301 acctgagttc gattggatga caatagtttg ttctttttga gttccaaggt ctttggcctt
    27361 aacagacacg ataccgttct tgtcgatgtc aaatgttact tcgatttgag gaattccacg
    27421 aggtgcagct gggatatcag tcaattggaa gcgtccaaga gtcttgttat ctgctgccat
    27481 tgggcgttca ccttgaagaa cgtggatatc aacggctggt tggttgtctg ctgctgttga
    27541 gaagacttgt gatttagatg ttgggattgt agtgttgcga tcgataagtt ttgtaaatac
    27601 tccacccatt gtttcgatac caagtgacaa tggcgttaca tcaagaagga caacgtcctt
    27661 gacatcacca gtaatcacac caccttggat agccgcaccc atagcaacta cttcatcagg
    27721 gtttactgat ttgtttggtt ctttaccagt ttcagcttta acagcttcaa caacggcagg
    27781 gatacgagtt gaaccaccaa caaggataac ttcgtcgatt tctgacaagc tcaaacctgc
    27841 atctgaaagg gcttgacgaa ctggaacttt tgtacgttca acaaggtcac gagtcaaatc
    27901 gtcaaatttc gcacgagtca aagtcatttc caagtgaaga ggtccagcct cacctgcagt
    27961 gataaatggc aagctgattt gtgttgaagt tacaccagaa aggtctttct tcgctttttc
    28021 agccgcatct ttcaaacgtt gcattgccat cttgtcagta gacaagtcga taccgttttc
    28081 tttcttgaat tctgctacca agtggtcaat gattttttgg tcaaagtcgt caccaccaag
    28141 tttgttgtcc cctgcagttg acaatacgtc gaagacaccg tcacccaatt caaggataga
    28201 gacgtcgaat gtaccaccac caaggtcaaa taccaagatt ttttcttctt tgtcagtctt
    28261 gtccaaacca taagcaagag ctgctgcagt tggttcgtta acaatacgtt ctacttcaag
    28321 accagcaatt ttaccagcgt cttttgttgc ttgacgttga gcgtcgttga agtaagccgg
    28381 aactgtgata acagctttgg ttactttctc accaaggtag tcttcagcgt agcctttcaa
    28441 gtattgaagg atcatagctg agatttcttg tggagtgtat tcttttccat ttgcagaaac
    28501 tttttcagaa gttcccatct tagatttgat agagataact gtatctgggt ttgtaactgc
    28561 ttgacgtttt gcagcatcac caacgatgat ttctccgttt ttgaatgaga ctacagatgg
    28621 agttgtgcgg tttccttctg ggtttgcgat gattttgctt tcagttcctt caagaactgc
    28681 aactgctgag tttgttgtac ctaagtcaat accgataatt ttagacatgt gtttttctcc
    28741 ttgttagtta attttctatt tttctttttg atactcttct taagtggcga cgccgtcaga
    28801 gcttgacttc gtcagtctct tttactaaac tttgagccta aggtctcaaa atttgcgcaa
    28861 atagcgccac ggcgaagagt atcgtctttg gttcgcttcg ctcactatta caaagcaaaa
    28921 catattttat ctttcttcat agtttattgt cgtttcggac aagttttcta ttatgtaaat
    28981 tgcgacacga ggagtcgaaa tcgattttat ttcgacgacg agttagtaag gaagctaggc
    29041 aaacgccata gcaattgccg ttttctgacg agttgcttta gctaccgtca gaattgccga
    29101 atcgaacacg ccctaagctc tgagtaaaaa agatagattt tcttgtgttc atcgaacact
    29161 tcgtcaatct cctattttta ctgcgagctt tttacgggct ttgtatctta gttatacacc
    29221 actaccattg ctgggcgtag gatgcggtca tggagtttgt agcctttttg aaagacttgg
    29281 gcgatggtat ctactgggtg ttcatcgtct gctgggagag tttggatggc catatggtag
    29341 ttatggtcaa attcgccatc tgctgcgatt tcttcaattc cttcttcttt caaagcgtga
    29401 atcaagcttt cttgcaccat ccccaagccc ttcttcacat catctgtcaa accttcaact
    29461 gcaagtgcac gctcaaggtt gtcaagagat ggtaagattg cttttgccaa gtcctggcta
    29521 cgataacgtt gcaagttttg acgttcttca ttggcacggc gttggatatt ttgcatttct
    29581 gcatgagcgc gaagatattt gttttcgaac tcatctgcac gttcatttgc caagtccaac
    29641 tcagactttt caggagttgt ttcttcagct gtttccacaa cttcctcttc ttgaacttct
    29701 tctacttctt cattttttat atcttgggcc atgttcgcct cctttaatga tttcaatctt
    29761 aatgtacttc gtaatgatta ctgctgaggt agcggtaaaa atctgtcaac ttcatggtca
    29821 aaacacggtt gaccacattg atttgattga ttagctgttg gtaatccaga ttaactggac
    29881 cgataatggc tagaattcca actccccgat aaggaatgag gaacttacta ctaatcaccg
    29941 ctaggtcagc taaacaggac tcttgaccgt ctgcaacacg aacattttgc atctgatcct
    30001 cacgcaaccc ctcacgaatc tccaaggcca ccttttgcgg ttggtcaaag aactgatagg
    30061 ctgctagatt ggcaaaattc aagagattga ccttgcccgc catcacaatg ttttcgttga
    30121 acatttcctt aaagatgtgt tcaaagagat cgatgacatt atccgttgtt gtaaagtaac
    30181 gctggataat ctgcggaatc tccgtccgaa tcttgtagtg aatatctaaa acggtgtgac
    30241 cgaggaaacg ttcctgaatg atgctcttca gtttcagcaa atcctcctgc aagaagttcc
    30301 ttggaatcag aaactgacta gtaaccgttc gcgactcgtc tagggtaaat accgccaagg
    30361 ctgtatgttg ccccaaaaca acgatatcaa aggctgtcaa acgttgcctg ctcggctcaa
    30421 catccagtgc cactaccgta cagccactca ggtctgttag caagttagca gcctcttgca
    30481 gaatatcctc caatttgaag aattcctgat caaaggcttt gacaatctca tatacctcat
    30541 tttcagccag tcggtcaaaa tccagtgagt gtttcacata gtactgaaaa ccagcaacac
    30601 ttggcatccg accgcttgaa gtatgagcct tctcaagcaa cccttgtttt tctagttccg
    30661 ccatgtcatt acgaatggtt gcactgctag agttaataga ctcttgcaag gcttttgatc
    30721 cgacaggttc gtgcgttttg gtaaagatgt caataatcag atttaaaata tcctgctgac
    30781 gctctgtaac catctcatca ctcctctctg tctgatcaat tagcactcaa tgcatccaag
    30841 tgctaactta tgattctatt atacaccctt agaagagaat gtcaagacaa aaactcaaaa
    30901 aattagcact cttttataaa gagtgctaaa aatcaatctg aagacctaga accttgctat
    30961 tcatctactc ggtatttcct ttttagtctg aaataaccat gaattagata agaaatcaga
    31021 aaagcatata aaacaaaaat aagaaagaaa gacatagaaa gatcctctct aaacaaactc
    31081 atacaaacaa caagaccacc taagaaagta gctatacagg aacgaagtct agatcgcata
    31141 acttcccatt tgagcccctt actcatatag acttgatcct ctggaagtaa atcagaagac
    31201 gatttacgaa gaatcgaaca agaacctgct cctatcaatt cccaacctct atctctaaaa
    31261 tcttgcagtt cacgcttatg ctctttaaga aatctagaat catagatacg atagataaca
    31321 tcgtccggtt gaccttgctc aaaatagaac aaaccaaaac gactagttct atacctccaa
    31381 cctttcaaat gcatctcatg taaatattct tctttcttgt ccaaatcaac aatggtgaaa
    31441 atccgaaatt ctactctgct attcattgtc ttaccccaaa attagaaaac atgcctagcg
    31501 ttatttatta gataattctt tccacttttg actcaatctc caaaaaatat aagaaatctg
    31561 aatcgcaaaa actatcaata aaacccaatc tattatgaaa atcaaaaaca cttcccaact
    31621 gaaagaacta cctccagtga caaactttga gaaaaacggt agtagagcta aaaagagaag
    31681 caaaatagga agcatccgca ttgttaaaat ccttttggca taaaaaaatc tttatttaaa
    31741 cgaaaatatt atggcaaaat ttacgccagt ttttgaacgg ctgatgtaga tattttatac
    31801 tttcaaaatg tttaaatgtg attatttatt tttgaaaaat agctcaccag cccgactgaa
    31861 agtgcttata gaatgataat aagtcgcctg ccgaaaacag cgaaaaatag cagtgttatg
    31921 cggagataat ctgacgcgat gcgaaagtat attgcatact tattttcaac aatttagcag
    31981 agtattttta taagtgtgat ataatagaag tataatttgt tctgatagtt tattttatgg
    32041 agaagtagat ttttagaatg cggaggattc aatatggttg agtttataaa gtctaagaaa
    32101 gaaatgagtg aggaggatat taaagcaaat ttcatcactc ctgctattgt atccaaagga
    32161 tggaaaaatg gtgagcatat cgcttacgaa gaatacttca ctgatggtcg aattgaagtt
    32221 agaggagata aggctcgtcg taaagaagga aaaaaatcag actattcact gtattaccaa
    32281 tttggaactc gaattgcaat tgttgaggca aaggataata aacacagcgt tcgagcagga
    32341 ttacaacaag ctattgaata tggagagatt ttagatgttc catttgttta ttcttcgaat
    32401 ggtgatggct ttattgaaca cgaccgtatc acgagagaag aacgtgagct ggagttagac
    32461 gaattcccta ctcgtgaaga attattttct cgtatgacga aggaaaaagg attgacgtac
    32521 gaaattacag aagctatctc aactccatac tatacagacg ccttctcaat gaaaacgcca
    32581 cgctattatc agcaaatagc tatcaaccgt actattgaaa cagttgccag aggacaaaaa
    32641 cgagtaatgt ttgtgatggc aacaggaacg gggaaaacgt tcatggcttt tcaaattatt
    32701 catcgccttc gaaaagctgg tttggctaaa cgagttttat tcttagcgga tagaaacatc
    32761 ttagtagacc aaacgatggc tgaagacttt aagccattcg aaaaggtaat gacgaaaatt
    32821 acaccaaaac ttttgactgc tcctgaaaaa ttaaattctt ttgaaattta tctagggctt
    32881 tatcagcaac taactggtga agatggaact gaaacacatt atcaaaaatt tgataaagac
    32941 ttctttgatt taatcgtaat tgatgaagcg caccgtggtt cagctaagga aaacagtaac
    33001 tggcgtaaga taattgatta tttcagttct gcgacacaga ttgggatgac cgctactcct
    33061 aaagaaacca agaatgcttc caatacggaa tactttggtg agccaatcta tacttatagt
    33121 ttaaaacagg gaatcgagga tggttttttg gctccatatc gtgttatgag ggttaattta
    33181 gatgtggatg tggatggtta tcgtccagaa actggaaaag ttgatactaa cggacaatta
    33241 atagaagata ggtactacgg caggaaagat tttgataaaa ccattgtcat tgatgataga
    33301 acgcaaagag ttgccaagtt tgtttctgat tatatgaagc aaaacaatgc acgatttgat
    33361 aaaacaattg ttttttgtgt tgatattgac catgccgagc gaatgcgtgc tgcacttgta
    33421 aaagagaatc tagacttagt ccaagaagac tatcgttatg tcatgcaagt aactggtgac
    33481 aacgctgaag gaaaagctca actggataac tttatggatg tcaattctaa ttttcccgct
    33541 atggtaacaa cgtctaaatt attaacgaca ggagttaatg ctaaaacatg tcgtttgatt
    33601 gttttagact ctaatatcca atccatgact gaatttaaac aaattattgg tcgtggcaca
    33661 cgtctttatc ctcaaaaggg gaaagaattt tttacgatta ttgattttcg aaatgttacc
    33721 aatttgtttg ctgaccctga ttttgatggt gagccagtga aggtgctgga aacaggtgcg
    33781 aaaacagtca gtggttccac gcccggtttc gtagatgagg aaggtgaccc agtagaaaaa
    33841 tatatcgtta cagacaagca ggttaccatt cttaattcta ctgttcaagt attggatgaa
    33901 aacgggaaac tgattaccga aagcctgacc gactacactc ggaagaatat cttaggtagc
    33961 tacgccactt tgaacgattt tatcacagtt tggcatacgg cggataaaaa gaagcttatc
    34021 ttagacgaac tttataaaaa aggagtttat ctagatgcta ttcgagagtc ggagggaata
    34081 tcagaacaag aaatcgatga ttttgattta ctcctaaaac ttgcctatgg tcaaaaagaa
    34141 ttaaccaaaa cggaacgtat caataagctc aaacaaagcg gatatttata taaatatagt
    34201 gaggaagcgc gtgctgtttt ggaaatttta ctgaacaaat acatggataa aggtattgga
    34261 gaactcgaaa gcattgaaac attaaaactt ccagaatttc agatatatgg tggaaccttc
    34321 aaaatcatca atacttattt tggagataaa aaacgatatt tacaagcaat taaagaattg
    34381 gagcaagagc tatttacagt agcttaatga aaggaaagta tgtcaattac atcatttgta
    34441 aaaagaattc aagatatcac tcgaaacgat gctggtgtta atggtgatgc tcaacgtatt
    34501 gagcaaatgt cttggttatt attcttaaaa atttatgata gccgtgaaat ggtttgggaa
    34561 ttagaagaag acgagtatga gtcaattatc ccagaggaat taaaatggcg aaattgggct
    34621 catgctcaaa atggggaacg ggtattgaca ggcgatgaat tacttgattt tgtcaataac
    34681 aagttattca aagagttgaa agagcttgaa ataacttcaa ttatgcctat tcgaaaaacg
    34741 attgttaaat cagcttttga agatgcgaac aactatatga aaaatggcgt cttgttacgc
    34801 caagtcatca atgttattga tgaagttgat ttcaatagcc ctgaagatcg tcattcgttt
    34861 aatgatattt acgaaaaaat tcttaaagat attcaaaatg ctgggaactc aggagaattt
    34921 tatacgccac gtgcagcgac tgattttatt gccgaagttc ttaacccaaa acttggagaa
    34981 tcaatggcag accttgcttg cggaacagga ggcttcttga cttcgactct gaaccgttta
    35041 agtagtcaac gtaaaactag tgaagatacc aaaaaatata atacagctgt ttttggtatt
    35101 gaaaagaaag catttcctca tcttttagca gttacaaatc tgtttcttca cgaaattgat
    35161 gaccctaaaa ttgttcatgg aaatactttg gagaaaaatg ttcgtgaata tacggatgat
    35221 gaaaaatttg acattattat gatgaatcca ccttttggag ggtcagaatt agaaacaata
    35281 aaaaataact ttccagcaga attacggagt tctgaaacag ctgatttatt tatggctgtc
    35341 attatgtatc gtttgaaaga aaatggtcgt gttggagtta ttttacctga tggttttcta
    35401 tttggtgaag gtgtaaaaac tcgcttgaaa caaaaactgg tagatgagtt caacttgcat
    35461 acgattatta ggttgcctca tagtgtcttt gcaccgtata caggaatcca tacgaacatt
    35521 cttttctttg ataaaacaaa gaaaacagaa gaaacttggt tttatcgttt agatatgcca
    35581 gatggttata aaaatttctc gaaaactaag ccgatgaagt cagaacactt caatcctgtt
    35641 cgtgactggt gggaaaatcg tgaagagatt ctggaaggta agttctacaa atctaaatca
    35701 tttacaccta gtgaattggc tgagttgaat tataatttag accagtgtgg ctttccaaaa
    35761 gaggaagagg aaatcttaaa tccctttgag ttgattcaga attatcaagc ggaaagagca
    35821 actttaaatc ataagattga taatgtatta gctgatattt tgcagttgtt ggaggacaaa
    35881 taatgacacc agaacaactt aaagcaagta ttctccaaag agcgatggaa gggaaattag
    35941 tgccgcaaaa tcccaatgac gaacctgcaa gtgaattatt aaagagaatt aaagctgaaa
    36001 aagaaaaact tatcagtgaa ggaaaaatca aacgagataa aaaggaaact gagatatttc
    36061 gtggtgatga tgggaaacat tatgggaagt ttgctgatgg aagcactcaa gaaattgatg
    36121 ttccttatga tattcctgat acttgggagt gggtgaggtt ttctacattg gttgaaattg
    36181 tcagaggtgg ctctccacga ccaatcaaag attatcttac ttctgaagta gatggaataa
    36241 attggataaa aataggtgat actgaaaagg gtgaaaagta tataaataat gttaaagaaa
    36301 aaatcaaaaa atcagggctt aacaaaacta gatttgtaaa aaaaggtaca tttttgttaa
    36361 ctaattctat gagttttggt agaccttata ttttgaatgt tgatggtgca atacacgatg
    36421 gatggttggc tatttcgaac tatgaaaact cattaaataa agattaccta ttctatattc
    36481 tttcatcaaa tgtagtttat tctcaatttc tatctctaat tagtggagct gttgtgaaaa
    36541 acttgaatag tgataaagtt gcttctattc ttatccctct ccccccacta tccgaacaac
    36601 aacgcataat agaagcaatc gaa
//
LOCUS       DBEJJV010000020        35610 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.020, whole genome shotgun sequence.
ACCESSION   DBEJJV010000020 DBEJJV010000000
VERSION     DBEJJV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35610
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.020"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(542..1714)
                     /locus_tag="ACL3GT_001134"
                     /pseudo
     CDS             complement(542..1714)
                     /locus_tag="ACL3GT_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730289.1,RefSeq:WP_050084071.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1695..1889)
                     /locus_tag="ACL3GT_001135"
     CDS             complement(1695..1889)
                     /locus_tag="ACL3GT_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0516810.1"
                     /translation="MKIIQQQSAIIDSLTNELSLLCEQVAYLTQKLSGKSSEKSVCPF
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(2059..2409)
                     /gene="tnpB"
                     /locus_tag="ACL3GT_001136"
     CDS             complement(2059..2409)
                     /gene="tnpB"
                     /locus_tag="ACL3GT_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0516811.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTPEQVDWLMKGFS
                     ITPKINLSESRDFY"
     gene            complement(2390..2575)
                     /locus_tag="ACL3GT_001137"
                     /pseudo
     CDS             complement(2390..2575)
                     /locus_tag="ACL3GT_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2879..4441)
                     /gene="guaA"
                     /locus_tag="ACL3GT_001138"
     CDS             complement(2879..4441)
                     /gene="guaA"
                     /locus_tag="ACL3GT_001138"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HGR0516812.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CLYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4583..5281
                     /locus_tag="ACL3GT_001139"
     CDS             4583..5281
                     /locus_tag="ACL3GT_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0516813.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(5324..6220)
                     /locus_tag="ACL3GT_001140"
     CDS             complement(5324..6220)
                     /locus_tag="ACL3GT_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HGR0516814.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(6229..7164)
                     /locus_tag="ACL3GT_001141"
     CDS             complement(6229..7164)
                     /locus_tag="ACL3GT_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HGR0516815.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(7161..7886)
                     /locus_tag="ACL3GT_001142"
     CDS             complement(7161..7886)
                     /locus_tag="ACL3GT_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HGR0516816.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7970..8605)
                     /locus_tag="ACL3GT_001143"
     CDS             complement(7970..8605)
                     /locus_tag="ACL3GT_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HGR0516817.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(8607..9434)
                     /locus_tag="ACL3GT_001144"
     CDS             complement(8607..9434)
                     /locus_tag="ACL3GT_001144"
                     /EC_number="3.-.-.-"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0516818.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9456..9791)
                     /locus_tag="ACL3GT_001145"
     CDS             complement(9456..9791)
                     /locus_tag="ACL3GT_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HGR0516819.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9792..10508)
                     /locus_tag="ACL3GT_001146"
     CDS             complement(9792..10508)
                     /locus_tag="ACL3GT_001146"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF021127.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HGR0516820.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRAQAPLVIKEVNAIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIVY"
     gene            11021..11632
                     /gene="def"
                     /locus_tag="ACL3GT_001147"
     CDS             11021..11632
                     /gene="def"
                     /locus_tag="ACL3GT_001147"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HGR0516821.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11677..12405
                     /gene="rlmB"
                     /locus_tag="ACL3GT_001148"
     CDS             11677..12405
                     /gene="rlmB"
                     /locus_tag="ACL3GT_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HGR0516822.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRTVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12444..13355)
                     /gene="trxB"
                     /locus_tag="ACL3GT_001149"
     CDS             complement(12444..13355)
                     /gene="trxB"
                     /locus_tag="ACL3GT_001149"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HGR0516823.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13421..13645)
                     /locus_tag="ACL3GT_001150"
     CDS             complement(13421..13645)
                     /locus_tag="ACL3GT_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HGR0516824.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13723..14466)
                     /locus_tag="ACL3GT_001151"
     CDS             complement(13723..14466)
                     /locus_tag="ACL3GT_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0516825.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14466..15266)
                     /locus_tag="ACL3GT_001152"
     CDS             complement(14466..15266)
                     /locus_tag="ACL3GT_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0516826.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15424..15780)
                     /locus_tag="ACL3GT_001153"
     CDS             complement(15424..15780)
                     /locus_tag="ACL3GT_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR0516827.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15793..16305)
                     /locus_tag="ACL3GT_001154"
     CDS             complement(15793..16305)
                     /locus_tag="ACL3GT_001154"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HGR0516828.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(16305..16799)
                     /locus_tag="ACL3GT_001155"
     CDS             complement(16305..16799)
                     /locus_tag="ACL3GT_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HGR0516829.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16934..17380
                     /locus_tag="ACL3GT_001156"
     CDS             16934..17380
                     /locus_tag="ACL3GT_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HGR0516830.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            17377..18024
                     /locus_tag="ACL3GT_001157"
     CDS             17377..18024
                     /locus_tag="ACL3GT_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HGR0516831.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(18045..18626)
                     /gene="pdxT"
                     /locus_tag="ACL3GT_001158"
     CDS             complement(18045..18626)
                     /gene="pdxT"
                     /locus_tag="ACL3GT_001158"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HGR0516832.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18627..19502)
                     /gene="pdxS"
                     /locus_tag="ACL3GT_001159"
     CDS             complement(18627..19502)
                     /gene="pdxS"
                     /locus_tag="ACL3GT_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042819 - vitamin B6 biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HGR0516833.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19654..21033)
                     /gene="nox"
                     /locus_tag="ACL3GT_001160"
     CDS             complement(19654..21033)
                     /gene="nox"
                     /locus_tag="ACL3GT_001160"
                     /EC_number="1.6.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="H2O-forming NADH oxidase"
                     /protein_id="HGR0516834.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            21327..22250
                     /locus_tag="ACL3GT_001161"
     CDS             21327..22250
                     /locus_tag="ACL3GT_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HGR0516835.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            22310..22915
                     /locus_tag="ACL3GT_001162"
     CDS             22310..22915
                     /locus_tag="ACL3GT_001162"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0516836.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22934..24178
                     /locus_tag="ACL3GT_001163"
     CDS             22934..24178
                     /locus_tag="ACL3GT_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HGR0516837.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSS
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24401..24658)
                     /locus_tag="ACL3GT_001164"
     CDS             complement(24401..24658)
                     /locus_tag="ACL3GT_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HGR0516838.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24700..26736)
                     /gene="glyS"
                     /locus_tag="ACL3GT_001165"
     CDS             complement(24700..26736)
                     /gene="glyS"
                     /locus_tag="ACL3GT_001165"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HGR0516839.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKGKRLSFEAI
                     QTFSTPRRLAVRVTGLADKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEIGQAVEAIVPGIVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGQETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKASLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26996..27913)
                     /gene="glyQ"
                     /locus_tag="ACL3GT_001166"
     CDS             complement(26996..27913)
                     /gene="glyQ"
                     /locus_tag="ACL3GT_001166"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HGR0516840.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(27932..28693)
                     /locus_tag="ACL3GT_001167"
     CDS             complement(27932..28693)
                     /locus_tag="ACL3GT_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR0516841.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28966..29808)
                     /locus_tag="ACL3GT_001168"
     CDS             complement(28966..29808)
                     /locus_tag="ACL3GT_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HGR0516842.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLESLKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTTAVQSGAPRVD
                     DVDF"
     gene            complement(29923..31314)
                     /gene="pgdA"
                     /locus_tag="ACL3GT_001169"
     CDS             complement(29923..31314)
                     /gene="pgdA"
                     /locus_tag="ACL3GT_001169"
                     /EC_number="3.5.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050119 - N-acetylglucosamine deacetylase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-N-acetylglucosamine deacetylase
                     PgdA"
                     /protein_id="HGR0516843.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31552..31920)
                     /locus_tag="ACL3GT_001170"
                     /pseudo
     CDS             complement(31552..31920)
                     /locus_tag="ACL3GT_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            32141..33118
                     /locus_tag="ACL3GT_001171"
     CDS             32141..33118
                     /locus_tag="ACL3GT_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0516844.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSNRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            33115..34197
                     /locus_tag="ACL3GT_001172"
     CDS             33115..34197
                     /locus_tag="ACL3GT_001172"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0516845.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTINLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(34261..35291)
                     /locus_tag="ACL3GT_001173"
                     /pseudo
     CDS             complement(34261..35291)
                     /locus_tag="ACL3GT_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        10593 a         7873 c         6378 g        10766 t
ORIGIN      
        1 ttaataattt ccatatcttt agggaaatta tttatttact taccataatt aaagagatga
       61 gagataaata tcggcagtct tcggactgcc tttatttttt tacttaattt aatgcagtaa
      121 atcatacgat tgaaaggaat ctgcgttata tgctataatt aggtagttaa tctatacatt
      181 tagaaaggta aaatatagaa ttggagaatg atatgggatt ttcatataat aaattgtaac
      241 cgcccaataa cgaagtctat tgaaaaatct ccagattagt gaactcacgg atagttccta
      301 atctggagat ttcttatttg cacttttctt gtacaacttt agtccacggt aaataggcct
      361 ctaaaacctc tttgtttacg agagtttcca cgtttggaag acattctaga agataggata
      421 gatatttctc actatttata atggattgaa ataagatatg aacaaatcga ttaggaaagg
      481 aaaattgatt tatagaaatg ttttagcagt cgatgcgtac tgttatagat tcaacgcact
      541 ataattgatg acgtttagct gtttccaaca aactcataat aatagctctt gctttagctc
      601 cttcaaaact ttgagaaaat aaccaccctc gcttttttaa actgagctta ggctaaaaga
      661 gtccactgga ctcttttact ccgtcccata accaatgatt taatggcgca ttcagctaga
      721 ttattggaaa ggaccagatg tccgtctttc aaaatagtct taaaggtttc tttatacttg
      781 aggctatact tgaggctgta ttcaattgcc cttcctagtt ttgaacccga taaaactgac
      841 tgacgccggc accaagcaaa gaaatcttcc attaggggtt ggagatgttc ttgacgtttc
      901 tgtagtcgtt catcagctgg caaagcctcc cagtttcttt ccaaggaaaa taactgatta
      961 caataagcta aacctttagc tcctaaggat gatttattcg cttgcttggg ggtcgcttca
     1021 aaaaacttcc ttctcacatg tacccaacat ccaacaagtt cagcttcttc cagttgacaa
     1081 taagcttcta gcggttcgca gtttaccaag cttagcgtcg ccttgctcct aaaccttgga
     1141 ctgctatcgc ataggcagaa ctagaggact aaagtcctaa gttactgccg caacatatca
     1201 caatgcacat agccagaata atctcctagg aattcttgca ctaccgaacc actccgacgc
     1261 tgatcatggt ggtacagcgt gattgcttga ttctcagctt tcccagacaa aaaggtccaa
     1321 tagtaggtca gatggctatc attctctaga acccgatagg aggtttcatc tgcatgaagt
     1381 aagggctgaa tcaatagtct cgttataaag gggctttagg aataggagct tttacaattt
     1441 tatcacttgg attattctta ctgcatgttt ggcatttgta agcgtgttgg atatgatcca
     1501 ctctttttaa ttgcgcagga ataaagacca attcttgtcg ttgaaggctc gctccaatct
     1561 cttttaaatc gtcctgacaa tcagggcaaa tgctctcttc tacttgatga tgaacttctt
     1621 ctgaatcaaa ttgggcaaga atagcttgac gtttcccttt agatttctta cgtttgtagg
     1681 taatttcctc tgtttcaact gggaacatct ccatctttct cagatggaga ctcttcctca
     1741 aaaaggttga gttgtccaaa agggcaaaca cttttctcag aggattttcc agagagcttt
     1801 tgcgttagat aagccacttg ttcacacaga agggaaagtt cattagtgag actatcaatt
     1861 atagcactct gttgttgaat gattttcaat cttctcccat agactttcct ccttatttcc
     1921 taactttatt atatagtgta ttgaatctat aacagtacac cttgactgct aaaatatttc
     1981 tataaattaa tttgactttc ctgatagaga tgttcatatc ttatttcaat tcactatact
     2041 aaaaagaaag tcctcatttc aatagaaatc acgactttct gataaattta ttttgggagt
     2101 gatagaaaag cccttcataa gccaatctac ttgttcaggt gtgagagctt tgacatcctt
     2161 ttctgtactg ggccaagtca gtctgccgtt ctcaaagcgt ttatatagta gccaaaatcc
     2221 ttgaccatcc cagtaaaggg ctttaaagcg gtctttacgt ccaccacaaa agagaaaaac
     2281 ttgaccggag aaaggatcca attcaaagtg ggttttaacc agataagcca gtgaatcgat
     2341 tccttgtctc atatcagtct tcccacacac gagatagacc tgccctaggc tagatagatg
     2401 aattgtcata gagcaacacc ttatccaaaa gctgttctac catttcgaga ttgagagatt
     2461 gaaaaaaact tacttcaagc ttgccaatac gaatttaaag cagaatatca tttctctttt
     2521 tagaatcaaa aggacgagat tgtggaatct ctacaggaac aataggttgt ggcattaaaa
     2581 tatcctccaa tagttttact ttactaatag tatacaggag gaactccatg aatgatagat
     2641 accttgttat gacgcgctta ctatattaga aagttggctc tctaattaaa ttaattctca
     2701 ttatatatat caaaagaccg cagtttgaaa actacggtct aattttttgt ccaaatgtaa
     2761 atcacttgga actattattc aatttattct ttttagtaaa tgttcccgtt ttaatcccag
     2821 ttacagtttt taatcctctg taaccgttga ttttacaaag cttttaattt ttttgcgatt
     2881 actcccactc aactgttgca ggtggtttac ttgtaatatc gtagacgata cggttaacat
     2941 gatccacttc atttacgata cgtactgaga ttttttgaag tacttcccat ggaattttgg
     3001 caaaatcagc agtcatacca tcgatagaag tgatagcacg gattgcaatc gtgtagtcat
     3061 acgtacgacc gtcacccata acaccgactg aacgaacgcc tgtgttaaca gtgaagtatt
     3121 gccaaatatc gcggtcaagt ccagctttag cgatttcttc acgaagaata gcgtctgatt
     3181 cacgaacggt ttcaagtttc tcttcagtga tttcacccat gacacggata gcaagtcctg
     3241 gtcctgggaa tggttggcgc catacgatat ggtctggcat accaagctct gtaccaagag
     3301 cacgaacttc atccttgtaa agagtattga gtggttcaat caattcaaac tgcatatctt
     3361 ctggaagacc acctacgttg tggtgtgact tgatagtttg agctgtatcc gtaccagact
     3421 cgataacatc tgtatataaa gtaccttgag caaggaattt cacatctttg agcttgcttg
     3481 cttcgtcatc gaatacatag acaaactcgt taccgatgat tttacgtttt tgttcaggat
     3541 cagaaacgcc agcaagtttg tcaaggaaac gtttagcagc gtctgctttg acgatattca
     3601 aaccaaactt accaccgagc atgtccataa cttgatcagc ttcgccttta cgaagaagac
     3661 cgtggtctac gaagatacag atcaattgat cgccaatcgc tttttggaga agaaccccaa
     3721 cgacagatga gtcaacacca cctgatagac caagaaggac acgtttatca ccgacggttt
     3781 cacgaatttt tttgatctgc atgtcaatga aattatccat tgaccagtca cctttagcct
     3841 tacaaatgtt aagggcaaag ttacgaagga tatcatttcc gtatacagaa tgacgaactt
     3901 ctgggtggaa ttggataccg taaatgtgtt tatctgggtt ttcgatggct gcgtataggc
     3961 agtcagctga tgtacctgta cgaacaaagt cagcaggaat ctcagtaacc gcatcaccat
     4021 ggctcatcaa aacagtctgt tcatcaggtg ttgattcaaa aagcgctgat ggtgtgtgag
     4081 ttagggttga ttgaccgtat tcacgatttc cagcatcacc tgcaggaaca acttttcctc
     4141 caagtttatg ggtcaataac tgcataccat aacagattcc caaaattgga attccgagtt
     4201 cgaagatttc tgggtcaata tcaaatgaac catcttcata tacagaattt ggaccacctg
     4261 atagaataat tcctacagga ttgacttcac gaacttcagc agctgaaatt ttatggcttt
     4321 ttagttctga aaaaacacca atctcacgga tacggcgtga aatcagctgg ttgtactggc
     4381 taccatagtc caatacgatg attttttcta catcttgcaa atcagttgaa atgttgctca
     4441 tctttttcct ttctcaaaag aaatatcttt tctcaatatt ctatcacaaa taagggcgaa
     4501 ttaccaacta aacaaggcga agtttgactt tttctagttt attggggtac aatagagaaa
     4561 agatagaaat gaagtgaaaa atatgctacc tgcttatatg aaaatccatg atcagataaa
     4621 aaaggatatt gacgagcacc gttgggctat tggtgagagg cttcccagtg aaagagattt
     4681 agctgagcag tttgcggtca gtcgcatgac cctccgccaa gccgtatctc tattagtcga
     4741 agaaggcgtc ttagagcgcc gtgtaggaag cggcaccttt gtttccagta ctcgagtaca
     4801 agaaaagatg cgagggacaa ccagttttac tgaaattgtc aaatcccaag gtaaagttcc
     4861 ctctagccag ctcatttcct acaaaaaaac cattcccaat gagcaagaag ttgccaagct
     4921 aggaattttt ccaacggaca atattatccg aatggagcgg gtccgctatg ccgaccaagt
     4981 tcccctagtt tatgaagttg cttctattcc tgaaaaattc attaaggact ttaaaaaaga
     5041 agaaatcacc agtcatttct tccaaacctt gcaaaaacat ggctatcgta tcggcaaatc
     5101 tcaacagacc atctatgctc gccttgctaa agaaaagatt gcccactatt tggaagttga
     5161 aaaaggacat gctattcttg gattgaccca ggtttcctac ctagaagatg gtactgcttt
     5221 tgaatacgta aaaagtcaat atgtaggcga acgctttgaa ttttatcttg aaaataatta
     5281 gattaccacg caaaaactct ctgtcacgga caaagagtct tttttatttt tctaagaata
     5341 aatctttcaa agaaatcaaa gttacagcaa acaatatcat tgccatacca ataaaatcaa
     5401 tgggataaaa ttgttcattc attattaaga aggcaaagaa aaccgccgat attggctcaa
     5461 ttgaagccaa caagcttgac ttgaccggtc ctatcagact ggctccttta aggaaagctg
     5521 tataggcaaa gacagtcccg ataaggataa tgcctgcaaa cgcaaggaga aaatcaagac
     5581 tagtcgggat atcggcctgt agaacccctg taaaaggaag ggcgaccaaa cctgctatga
     5641 ccatccccac accaatgacc aagctgctcc cccacttttt aatcaaggct atgggtaaaa
     5701 tgatatacaa agcataagtc aaggcagaaa agagacccca gaacaggcca gcaggtgtca
     5761 tggataactg gtccaactgc ccatgtgttg cgatcaggaa ggttcctccg atggcgaata
     5821 tgatggaaac tatctctccc agtgtcggtg ccaccctatc cttgatacag ctataaatta
     5881 aaattccgac aggacaaaca tactgaagca ccgtcgctgt tcccgcattg gtctcctgaa
     5941 tagcagacag ataggcgaat tggttgagaa aaagaccaat cagagcaaaa ataagaagag
     6001 acagcaaact ctttctatcc tttaaaaaga ccagtatttt atcctttgca gtagcataag
     6061 ccaagagcat gagaattcca ccagcgatta aaagacgcaa gttggtcaag accagagccg
     6121 aaattccgtg tgccattagg tattggccac tcgttcctga caacccccaa gcaataccag
     6181 ccacaactgt tagtaaagtc ccttttaaac tatttgacat gtctctcctt actcttcttt
     6241 gcgaatcaag ttcatcactt gattgcggtc taatatccat tgagctctct cgtccttttc
     6301 ataggtacga ttcgatagga aaatagtggc ttcttgcttc tgacgattcc acatgataaa
     6361 ggtacctgta tagcccgtat ggtctagcca atctccttcc aaattccatg ctaaagaacg
     6421 ttccttgtca tccaaaggag aaaaattttg atttaagtct cttgcaaaat catctgctaa
     6481 atagtgttct aaaaagattt gtaaatcctt tatagtcgaa aataaaccag cactcccagc
     6541 atgtctaccc aggagacgag ccttgggatc atgcactatg cctgcctcta cacctctaac
     6601 tgttggaaca gcaagctcaa ctggcccaaa cttggtttcc gtcattcccc aaggtttcca
     6661 gacttgatcc tttaaaatca catccaaatc ttgattaaaa attctttcca aaataaagcc
     6721 caacagcaaa aaatggacat ccgaataaag aaaggctggc tgacttcgtc tgttgagatg
     6781 aaacatcgct tcctttaatt caggggctgt taaaagatca cgattaggaa taaaaggatc
     6841 aaggtctgtt gcatgagtca agagctggcg aatagtgatg tctggataat cactctcagg
     6901 taaaaaatct attaccagtc tatcaatatc taattgacct atttcccaca agaaggtaca
     6961 aactgtgcca accccaacaa ccttgctgac actagctagg tcataaacta gtcctgcctc
     7021 agtctgcaag ccatgctctg ggtcactctg gcctaaatag aactctgtcc attgattgtc
     7081 cttaaaatac gcaaaagagg ctccgggata aattcctgcc tcgatttgtt cttctatttt
     7141 tttaataatc ttggtccact tcatacttct tcaaaccaca attcaacatt atttctatct
     7201 ttacaaagga agaatttttc agacttagga ataaaatatt cagtagactc aaacttctgg
     7261 cgaagacttg ctatgtctaa ttcattgacc aagaacttga gcatagataa gtcccaggta
     7321 accgtattgt ccacagtcaa atcctgcccc tgagctggaa taaaatcaag ggatgcccca
     7381 atttcagatg attccaagaa actttcgata tcagttggga gatgtaattc catagaaatc
     7441 tcaaatttac ttaaagaaat tgatgccaaa tctgtttgaa attcaggctt ttctcctact
     7501 tctactagac ttgctatgtc atcttccgca tgaatcaaaa tcaaatcatc ttctggtgag
     7561 aaaatttcaa aagcgtagcc attttgacct ttatataatc gatgaatcga atctgtttta
     7621 gataagattc cttcaatttc taagggattt tccaccttga caatcaatct agctagtttt
     7681 tttcttccct ctaccttacg agtacgcata ctgggagctt cttctaaaac cagcttttca
     7741 agacccgttt ggtcacctag tgacagaaag gccgattctt ctaacaaggc cttcattcca
     7801 agggtttcaa tataaaatgt ttcatttaat tttctattat tagcttttaa agtaggaata
     7861 atccgtacaa tctgatttac attcataaat tcctccgtca ctttttattt taaaggattt
     7921 tagaattttt tacaagatat tatgctcaaa tttaacatta tttagctatt tagtaaagat
     7981 agtctttcaa ggattttgac aaagcctgat aaccagcaat actgaggtgc agtccatcag
     8041 ttgtatattc ttttttgagt tggcctgctt ggtctgtcaa acaatcaaat actggcacaa
     8101 attccacctg catataggca gatgcaagct cttgataggc ttgattccag ttctgaattt
     8161 tttcattcga gcggatatag actgcctgct ggtactcctc tctctcattg acaggcaaaa
     8221 tggaaagcaa tttaatctct gtcaatggat aatcgcgagc aacggattga atgatagctt
     8281 cgagattatt gagagcctca ttcacaggaa catcctttcc gatatcattt gtcccaatca
     8341 gaagaaaaat tttatctact gctccaccat atagatgagc atcaaggttc tctagtaaca
     8401 gtcctgtctg atagccacga attcctcgat tgacaatcgt ctttgaagtc ccaaatagct
     8461 cctgtagagg ataatactcg acaatggaat ccccaataaa aagaatgttt ggttctacaa
     8521 cagaaatgtg atttaggtga cgatacttag tttgaatttt ttcttgttcc tttaggagcc
     8581 aattttctaa taactgtact gccacttcat tctccttttt ctaaccagtt ttccaagact
     8641 tgataaactc ctccttggct gttggctggt gctagagcag tcgccacagc tttggctttc
     8701 tcatcagcat tttccatcgc ataggcaatt ccagccattt caagcatttc aacatcattt
     8761 tcactatcac caaaagccat gatttcttgg gatttcaagt cccagcgctt gagtaattcc
     8821 tccaagcccc atgctttatg aatcccagct tggaggatat caatgcaacc atagccactg
     8881 gatacagctc ggacacggcc atcaaagaga gcattgattt cttccaaaac cgaactcaaa
     8941 cgttcctcac caacaaccat gctcatcttg agcacaccac caaagaggtc agatgttaat
     9001 tcatccacaa attgcatccg ttggtagaat ttttcaatca tttctggagt cataaaactt
     9061 tcaagatctg taaaaatcgt accttccttg acaaaatcac ccttcatccc cgttacaaca
     9121 aactggtcct gacacgctcg acccttgaaa tgagtcaaag ccttgttgac aatggcgtca
     9181 tcccatgtct gagcctgaat caattcattg ttttcaaaaa tacgagcgcc attagcaaca
     9241 accagaacca ctcgatccac caagggactc agtagttgtc tcatgcggtg aatttcattg
     9301 cccgtcgcaa tgacaaaacg aatgcccctt tgatccaact gatctaaaat cttttccaat
     9361 cgtgggagat caagctgacc tctagcatcc agcaaggtcc catccatatc tgtcgcaatt
     9421 accttaatca tcatttactt tcctctggat tcaagctaat accacttcaa tcccacatgt
     9481 tcattcattt ctttataggc tgtatcaatt cgttccttag tcgcttcatc taactggtca
     9541 cgatgactgc catcctctat aaaatcttcc aaaatataag tttggtaatg atacaaggga
     9601 tatccttctg gtgaaaaggt tccctttggt gttcgattga cccaagtagg atgagcttta
     9661 gctgttccga tagttgtttt tccatccttc ttcttgatgg tgacatccat gagaacacca
     9721 cgttcagtcc acttagcatt ctcttcatct cccatagatt caattcgttg attggaaatg
     9781 aagttcccca tttaatagac aatgagcttt ttatctccat ctttttccac cgtttcagat
     9841 ggttcaacaa cgtgaggatg ccctccaaag ataatatccg ctccccaatc aatcatcttg
     9901 tgataaagag ctttttgttc ttcagttggt tccaatcgat actcaacacc catctgaggc
     9961 atgataatgg tgatatctgc ttccttctct gcccgttcaa cttcagcctt tatcttatct
    10021 tcgtttaaat ctgaaagata acgattatag tcttcctgag aaatatactg ctcaattcca
    10081 ttgaaaccat aggaataggc taacaatgca accttgatag cattcacttc cttaatgacc
    10141 agcggagcct gagcacgtgg ttcgtgcgta taaactccga ttggagtgat tccagctttc
    10201 tcaataatat cggccattga aataactccc tcaatttgcg aatccaaaat atgattatga
    10261 gctaaatcca gcacatgata acctgcctcc ttaatagcat ccataacttc aacaggagca
    10321 ttaaagagaa gataacccgc taaataatga tccttattaa tggttccttc aaaatcacca
    10381 atagctaaat ctgcttgctt gagccaagga gtcacatact caaaattttc atgaaagtca
    10441 taggtaccgt cttctttttt agctgaaaag aaaagtccat cgtggtagag caaatccccg
    10501 tgggccataa ttctggcagt tttttcctct tcctactcct gagacttttg cttagtcccc
    10561 tcttgagaaa tagtatctcg tttttgacta gtcaagggat tccttggaag ctttcaaaca
    10621 acaagaccaa gcccattgat aaaccaactg ctagcaagag tatcgccaca aatcccttat
    10681 tgctccactt gcgataactc ctaaaaagtt taccaagccc ttcataaaac gaaaagctga
    10741 accaccctga tttcgatttt gtcttctttg tatcttcgtt ctccctactt tcttatgcaa
    10801 gccttttctt tttattatat cacagataag tatttctttc acaattgaat tgaacttcct
    10861 atctattttc tataaatcct aaatgccata atgctttcaa ttcttgtcat tttgtgatat
    10921 catgtagagg aaatgaacta atccacagtg gcttattcca agtataccac ttgggctttg
    10981 gcagtagcta actgcactaa acataatata aggagagaaa atgtctgcaa tagaacgtat
    11041 tacaaaagct gctcacttaa ttgatatgaa cgatattatc cgtgaaggga atcctactct
    11101 acgcacggtt gctgaggaag tcactttccc cctatctgac caggaaatca tcctaggcga
    11161 aaagatgatg caattcctta aacattccca agatcctgtc atggctgaaa aaatgggact
    11221 ccgcggtggt gttggactgg ctgctcccca gttagatatc tcaaaacgca ttatcgctgt
    11281 tttggtacct aatattgttg aagaaggcga aactccacag gaagcctacg atttggaagc
    11341 cattatgtac aatccaaaaa tcgtctctca ctctgttcaa gatgctgctc ttggcgaagg
    11401 agaaggttgc ctgtctgttg accgtaacgt gcctggctat gttgttcgcc atgcccgcgt
    11461 tactgttgac tactttgaca aagatggaga aaaacaccgt atcaaactca aaggctacaa
    11521 ctccattgtt gttcagcatg aaattgacca cattaacggt atcatgtttt acgatcgcat
    11581 caatgaaaaa gacccatttg cagttaaaga tggtttactg attcttgaat aaagaaaatc
    11641 ccgttgcaag acggggtttt gtgttataat agaggcatga aaacaaatga tattgtctat
    11701 ggtgtccacg ctgttaccga agccctcctt gcaaatacag gaaacaaact ctacctccaa
    11761 gaagatctcc gaggtaagaa tgttgagaaa gtcaaggaac tagctacaga aaagaaggtg
    11821 tccatttctt ggacatcaaa aaaatctctc tctgagatta ctgaaggtgc tgttcatcaa
    11881 ggttttgttc tacgagtgtc tgaatttgcc tatagcgagc tagattacat ccttgcaaaa
    11941 acacgccaag aagaaaatcc acttctattg attctagatg gtctaaccga tccccataat
    12001 ctgggttcta tcttgcgaac agccgatgcg accaatgttt caggtgtcat cattcccaag
    12061 caccgtactg tcggagtaac tcctgtcgtt gccaaaacag ccacaggtgc tattgaacac
    12121 gttccaattg cccgagtgac caacctcagt caaaccttag ataaacttaa ggatgaaggt
    12181 ttctggacct ttggaacgga tatgaacggt actccttgcc acaagtggaa tacaaaaggg
    12241 aaaatcgccc tcatcattgg aaatgaagga aaaggtatct ctagcaacat caaaaaacag
    12301 gtcgatgaaa tgattaccat tccgatgaat ggacatgttc aaagccttaa tgccagtgtt
    12361 gctgcggcca ttctcatgta cgaagttttc cgaaatagac tataaaaaag tttccagtca
    12421 tctgattgga aactttttta tgattaacta tgttctgtaa tgaatttata ggcttcttga
    12481 ccagcgatag ctccatctcc aaccgctgtt gttacttggc gaaggtcttt caagcgaaca
    12541 tctccaactg caaagatacc gtcgactgca gttttcatgt ggttatctgt cacaatccat
    12601 cctgcctgat cttggatatt caattcttta acaaaatcgc taagagggtc caaaccaaca
    12661 tagataaaga caccaccgaa ggcttgttct gtcacttgac ctgttttcac attttcaaat
    12721 acgactgatt ctactcggtt ttcacccttg atttccctta ctacagaatc ccagataaag
    12781 ctgatttttt cattcgcaaa ggcgcgatct tgtaaaacct tttgggcacg aagttggtca
    12841 cgacggtgaa caatggtaac agtcttagca aaacgagtca agaagagggc ttcttcaaca
    12901 gctgaatctc caccaccaac taccaataaa tcttggtcac ggaagaaagc accatcacac
    12961 acagcacagt aagaaacacc acgactgttc agttcttctt ctccaggcac tcccaaagga
    13021 cggtgtttag aaccagttgc tacgataact gtacgtgttt catatgtttg gtcatcagtc
    13081 atcactttct taaaatcacc atggtcttcg acattttcaa cataaccata aatgtgctca
    13141 acaccaagat tttcaagtgg ttcaaacatc ttttcagcca attcaggtcc actaatatta
    13201 gcgtatcctg ggtaattttc gatatcagat gtattattca tctgaccacc tggcagacca
    13261 ccttcaatca aagctacttt tagattgctt cgagcagcat acaaggccgc agtcatccct
    13321 gcaggtccag caccgataat aatagtatcg tacatataga ttccttcttt cttgttgtaa
    13381 ctatctttat tctaactctt tcttgtcaat cacgcaagga ttatgccttg aaaacaagaa
    13441 ttaaactcat aaccgcaaag gataatactg ggacaaccaa gactccaatc ataatcatat
    13501 catagagatg ggcttggcga gccctggctg tcttatcaac tcccgacatg gctctcagac
    13561 caatccaaat ccctaaaaaa atcagaacaa ggatggtggt caagatcaaa ctctcgaaat
    13621 ataaagaaaa tagttgcagt agcatgattt ctctcatttc tatctttttt aaagagtaaa
    13681 ctcagctagt ccaactaact gagttttcct ttatctatta tatcaaatat aagtccgttt
    13741 gtaactagcg aagaattctt ttgtccgctc ttctttaggg gtgtggataa tctcatccgg
    13801 agttccagac tcgatgattt tccccttatc taagaagaga attttatccg caacttgggc
    13861 tacaaaggac atgtcatgac tgaccaaaat catggtctga cctgacttag cagcatctgc
    13921 aatagacttt tctacttcac cgaccaattc tgggtcaagg gctgaagttg gttcgtctaa
    13981 gagcaaaaca tctggtttca tagcaagcgc acgcgctagg gcaacccgtt gcttctgtcc
    14041 acctgataaa tggcgaggat aatggttttc acggtccgaa agcccaacct tagccaactc
    14101 ttccttggca atcttagtcg cttcttggtc agataatttc ttgacaacaa ccaagccttc
    14161 tttcacatta tcaagtgctg ttcggcgttc aaataaatta aactgttgga aaaccataga
    14221 caacttacgg cgtagggcaa ggatttcttc ttgagtgatt ttagaaaaat caactgaaaa
    14281 accatcaatc tgaatagagc cactgtcagg tgtttcaaga taattgagac tgcgaagaaa
    14341 ggttgatttt ccagctcctg aagaaccaat caaggctacg acttctcctt tttgaatatc
    14401 caagttcaga tgatccaaga cagtctgtcc tgaaaaggat ttgcttaaat tcgaaatctt
    14461 aatcattaac gaaggtctcc tttcacatct gtttgcactg tatcaggtgc agaaatagcc
    14521 atttttctct cgatgaaacg accgaggctt tcaattccga tattgactac ccaataaaca
    14581 agggcaacgg agatgaagcg ttcaaaatag cgataatcag ctccacctag aatctgagct
    14641 tgggcaaaga cttccacaac acccgcacta aaagctagag atgttccctt ggtcaaaccg
    14701 atgagggaat taatcaaggt tggagtagct accaccgctg cattaggaat aatcactcgt
    14761 cgataaactt gcgctcgggt catacccaga ctgcgtgccg cctcaatctc accaggatta
    14821 actgagagaa tggctgcacg aatggtttca ctagcataag ctgcctcatt aaaggcaaaa
    14881 gcgacaatcg caaaagctgc agctggaatc gcattgatat tgagaccagt tccccattgc
    14941 tgattgaggg ctttcaaagc caaagggatt ccgtagtagg tcaacatgag ttgcaccaaa
    15001 atcggtgtcc cttttaagaa actaacaaag aaggcctgca agggatataa aatcttgaca
    15061 cgattgatct tcacaatggc aaaaagaagc gccaaaacca agccaaaaag ggcaccacca
    15121 attgtcaaca taattgttgt tggaagttgt tggacaattc tagggattcc atcaaagacc
    15181 gaacgtaggc taaacagctt gccatccgga atcaattgca tcaagttttg gtaccaatct
    15241 gatgctaaaa tcgttgtaac attcataaaa acatcctctt ctgataatga ttcattctac
    15301 catgcttctg ccgtcaatga aattatttgc tacggtcaga tacagacttt gtctacctac
    15361 tagtttatca tactttgaaa cagggaagtt atatatttta tctatcaaag agatagataa
    15421 aaactatttc agtcccagtt cttcataaga ttttcgataa ccgatttgct taacagttcc
    15481 attttctact aaaatgggcc gttttaacaa cataccgtca cttgctagca actcagccgc
    15541 ttcttggttt gacaaacttc ctaccttatc ttttagccct aattcacggt atttgatacc
    15601 actggtgttg aaaaattgct tcaattcaaa tcctgaggtt tctagccaat tcaaaatgac
    15661 ttcttggcta ggtgtttctt ccacgatatg gacggcttta tagtccacac ctaattgatt
    15721 taattcttgt tttgcttttt tacaagttga acatttgggg tattcgataa attctaacat
    15781 gtgcttctcc ttctatttgt ttatatcttt aaaatctacg ccttcatgct ccaagagcca
    15841 agctttcttt tccactcctg cagcatagcc tgtcagacgc ttgcctgctc ccaacacacg
    15901 atgacaaggt actaggatag accaaggatt gcgtcccact gctccaccaa ttgcttgagc
    15961 agaagccact tgcaggtctt gagcaatttg tccataggtc actgtctgac cataaggaat
    16021 gccctgtaaa tagtcccaaa ctctcttttc aaaattcgtt ccgattggcg ccaagagcaa
    16081 gttggataaa tcctgaggct tgcctttaaa gtaatcatct aagcaagcaa taactgggtc
    16141 taaaatagga tgactaacaa cttcttctat cgtttcatct cctagtcccc tctcaaaatg
    16201 cttctgctcc tgaacccaaa ttccatacaa ataatggtca tcagctacaa gtgatagaat
    16261 accaattggt gaggagtaga gtatttttac atacttcttt tgcattattt ctttaatttt
    16321 tgataggcca agcgttcgcc atctactggc accttaccaa cttgtttaaa accaagtttt
    16381 tcaaaaatat gttgcataac cttgttttca gcatgcgtat ctgagcgaaa atcaagataa
    16441 tcaaaacctt caatcaagcc ctctaagaag gtttgagcaa ctccttttcc ctgcacatct
    16501 gctgccacag caatacggtg aaagactaga tactctgact ctccagcttg ccagtttccc
    16561 tcataaatag cttcataggc ctcctctgga ctcttggtca cagcagcata ggctagcagt
    16621 tctccctctt ccaaggctac gtaggcttgc cctgagatga tatcatcgat aataacatct
    16681 gcatttggat agccattttg ccactggtca ctaccagcat ctgctaaaca ttttttggca
    16741 tcctccatca cctgcatgat ggcatctact tcatttggaa aagctaaacg aatttccatc
    16801 ttttttcctc atttctgact agtttctccc atcatagcat aatttaagta tttctacaag
    16861 cagttaaaac ttgactttgt gtttttgtta ttttataatc tagttatcaa aactatataa
    16921 aaaggagtta aaaatgaaaa ctaccttttc ctacccaaaa tgggcagaaa ttccaaacat
    16981 tgacctctat ctggaccagg ttttgctcta tgtcaatcag gtctgcgccc ctatctctcc
    17041 taataaagac aagggcctaa cagcatctat ggtcaacaat tatgtgaaaa atggttacct
    17101 gacaaagcct gacaaaaaaa aataccaacg ccaacagatt gcccgtttga ttgctatcac
    17161 aaccctcaag tctgtatttt ctattcaaga aatagcccag acacttaata ctctacaaac
    17221 tcaagcaagt tcagaccaac tctacgatgc ttttgtggac tacatgaacc aaggaattga
    17281 cccagctaac cctattatcc aaaccagctg ccaaaccgtt aaactctatc atcaaactct
    17341 agacttaatc gatcatactc aagaggaggt aatccaatga acactagtct taaactcagc
    17401 aaacaactca gttttggaga ggagattgct aatagcgtga cccatgctgt gggtgcagtc
    17461 atcatgctta tcttgctgcc tatttcatcc atctatagtt atgaagcaca cggattttta
    17521 tcctctatcg gcgtttccat tttcgtcatc agtctctttc tcatgttcct atcatccacc
    17581 atttatcact ctatggccta tggttcgacc cacaaatatg ttttgcgaat cattgaccat
    17641 tctatgattt acgttgccat tgccggatca tacacgcccg ttgtcttgac cttgatgaat
    17701 aactggtttg gctatctgat tattgtcatc caatggggaa cgaccatctt tggtattctc
    17761 tataaaatct ttgctaaaaa ggtcaatgag aaatttagcc ttgctcttta cctgattatg
    17821 ggctggttgg ttctggctat cattcctgcc attatcagtc aaacgacacc cgttttctgg
    17881 agtctcatgg taactggcgg actctgttat acagttggag ctggatttta tgccaagaaa
    17941 aaaccttatt tccacatgat ttggcatctc tttatcctag ctgcgtccgc acttcaatac
    18001 atcgctattg tttattacat gtaaaaaagt tgagaaattc aatctcaact tttttcttta
    18061 cacatattga taaagtactg gtgcaagcgc acatcatcag tcaattctgg atgaaaagaa
    18121 cttaccaaca tatttttttc ttgggctgca acaatttgat tgttcactgt tgctaaaatt
    18181 tctacaccct caccaacact actgataatc ggaccacgga taaaggtcat tggaatcttg
    18241 ccaactccct tacattctgc ttccgtgtag aaacttccta attggcgccc ataagcatta
    18301 cgctcgacca ccatatccat agttcctaga tgactctctt tctgagaagt gatttcctta
    18361 gccagcaaaa ttaagcccgc acaggtccca aacactggta agccagatag aatggcttct
    18421 cggatgggaa gtagcatgtt ctggtcacgt aagagcttgc ccatggttgt agactcacca
    18481 ccaggcaaaa tcaaacccga caagtcactc tgatcttgct gaaaatcatc tagatttctg
    18541 agttctacac tctcgacacc taattgatct agcacttttg catgttctgc aaaggcccct
    18601 tgcaaggcca atattccgat tttcatctat tttcctcgtt cagccatgag aatttggatt
    18661 tcattttcat taataccaac catggcttct cctaaatctt cagagatttg agctaggatt
    18721 tgaggattac ggaagttagt cacagcctta acaatggcac tcgctcgttt aacaggatct
    18781 cctgacttga aaatacctga accgacaaag accccctctg cccctaattg catcattaac
    18841 gcagcatctg ctggcgttgc aacacctcca gcagcgaaat ttacaactgg caattttcca
    18901 tgttcatgaa catattggac caattctaca gggacttgca aatccttggc agcaacataa
    18961 agctcgtcct cacgtaagtt ttgaatgcgg cgaatttcct gattcatcat acgcatatga
    19021 cgaacagctt ggacgatatc ccctgtccct ggttctcctt tggtacgaat catggaagca
    19081 ccttcagcga tacgacgcaa ggcttcaccc aaatccttag caccacagac aaaaggaact
    19141 tggaattctt tcttgtccac atggaaacgg tcatcagctg gagatagaac ttcactctcg
    19201 tcgatataat caatttcaat agcctctaaa atctgagctt caacaaaatg cccgattctg
    19261 accttagcca ttactggaat actaaccgct tcttggattt ccttaatcat ctttgggtcg
    19321 ctcatgcggg aaactcctcc agctgcacga atatcagccg gaattcgttc caaggccatc
    19381 acagctgccg caccagcagc ttctgcgata cgagcctgtt caggattctg cacatccata
    19441 ataacaccac ccttgagcat ctgtgccaag tttttattta gttcataacg attttcagtc
    19501 atttgtttta tcctcatcat ttgtattggt agctaccttt tcattttaag tcagaacaga
    19561 atgaagcaca agataaaaaa actataattg tatggggaca aattagctaa aaactatctg
    19621 accttaactt aaggccagat agctcattca tttttatttt tcagccgtaa gggcagccat
    19681 tgtgatgtag ttgtatggtt tgttgaagtg tggcaagaag aagaggtctg tcaatgccaa
    19741 tttatcaatt gtcacatgct cttggatagc aagtgagaac atgtggattc ccatgctaat
    19801 tgcaatatca tgtgaaacca tttgggcacc aagaatttca cggctatctt tgtcaaagac
    19861 aatcttaatt gctacttcat ggttgtcatg tttcatgaat tctggttttt gaagatcgtt
    19921 aaagcctgtt tcagttgcgt tgtaaccagc agctttcgct ttttcaagag tcaaaccagt
    19981 tgaaaccatg tgaagaccgt agattgagat accatttgaa ccttgaacac cgattccttc
    20041 caattcatgt ccacaagcat tgtaggcacc aacgatacca gtgcgaacag catttgaagc
    20101 aagagcgata tagcttgtat ctttacgagc attgtcataa acagtcgcac agtcaccaac
    20161 agcgtaaacg tctgggatag atgtttcttg tttcttgtct acaaggaagg caccgttgcg
    20221 gaagagttcg atcttaccac ctgcaagggc tgtgtttgga cggaaaccaa ctgcaaggat
    20281 aaccatatcc acgtcaaagc tttctttgtc agtaatcaag cgttcaactt taccgtcacc
    20341 ttcgattgct ttaacagttt gacctagagc caagcggatg ttgtgatctt ccaagttctt
    20401 cgccatcatt tgtgtgaagt ctttgtcata gtaaccgttc aagacagtat caacgatatc
    20461 aacaaggaca acttcttttc caagacgttc aaaggcttca gcaagttcaa caccgatgta
    20521 accaccacca acaacggcga tacggtcgag gtgttggctc ttgtcagaaa gtttattgat
    20581 aacttcttca gcattttggt acaatttcac gaattgtacg ttttcaagag ttgctttaaa
    20641 ttcgcggttt cctttaacaa tttcaacacc ttcgattggt ggcaagattg gtgtagaacc
    20701 tgtagcgaaa atcaattttt cgtatgattc tttgtgctct tttccttcaa cttccgctgt
    20761 aactactttg ttatcatagt cgattgaaag aacaggtgag ttcatgtaaa ctttagcacc
    20821 tttagcttcc aatttttctt tatcagaata gaacaagcct tcagcaccgt caatttgttc
    20881 accaatccaa agagccattc cacatcctag gaaagagatg ttagagtttt ggtcaaatac
    20941 aacaatttcg ttctcatttc caaaattatc caacatggta ttgatacatg ctgtaccagc
    21001 gtggttagca ccgactacaa cgattttact cataaaaatt tcctgccttc attctaaatt
    21061 taccttacta gtataccatt taccgttagc gtttacaagg ggggtactat tatttcagca
    21121 ttttttatca aaaataattc cccatttatc ctgttttcaa gcctgatgaa ttttatgagc
    21181 atatttcttg actttttcca aattttgttt gtgaaaattc taactttatg gtattataat
    21241 aacatgaaaa tgaaatgtaa gggcttcaat ttagatgatt atttgatatt acaacttatt
    21301 ttctataaga gaaaggagtt ggtagcttga ctcttcgttc acattctgaa cggctaatgg
    21361 ggactactat cactatttca ttagtggatg agcaagccga tatctttctc caaaaatcct
    21421 ttgacttgct caaagaactt gaataccgct tcaacgccaa tagtcaagaa tctgagttga
    21481 tggaaatcaa ttatcaagca ggaatagccc ccgtcacggt tcatccagac ctgtttgagc
    21541 tgatttcact tgggttagag catagcctag cgctctctag ccacctcaat atcagcattg
    21601 gtcccttaat tcaaacctgg cgtatcggtt tttcagatgc caaggtcgcc cagcctcaag
    21661 aaattgaatc ggtgctgcct ctaatcaatc ctcatggtat cgagttagat tcttctactt
    21721 ctactgtgtt tttaaaacag aaaggaatga agatcgatct aggttgttta gccaaaggat
    21781 acagtgcgga taaggttgcc caatttctta ggaaagaggg ggtgacttct gccttgatca
    21841 atctgggagg gaatatcctg accattggaa aaaatcaggc aagaggggat aacccatggc
    21901 aaatcgggat tcaagaccca gccaatccta ggggaaatca tttaatgacc atccctgttg
    21961 tcaataaatc tgtcgtgact tcaggcattt atgaacgtca cctgaccgtc gatggacaag
    22021 attaccatca catttttgac agtcaaacag gatatcctgt tgaaacggaa ctagcgagtc
    22081 taacaatcat ctctgataaa tcagtcgatg gcgaaatctg gacgactcga ctctttggag
    22141 aaagacctgc ttctatcctc tggcaagtcg aaagtttgga gggcatcgaa gtcatcctca
    22201 tcgataaaga aggccaccta agctgttctt caggaattcc tactctatag agacaactgt
    22261 ttcaatggaa ttttaaaatt gtattatgta aaaagagaaa ggaaatctca tgttaaaact
    22321 tattgctatt gttggaacaa attcaaaacg ttctacaaac cgtcaattgc ttcaatacat
    22381 gcaaaaacac tttactgaca aagctgaaat tgaacttgtt gaaatcaagg ccattcctgt
    22441 cttcaacaaa ccagctgaca agcaagtacc tgctgaaata ttggaaattg ctgctaaaat
    22501 cgaagaggca gatggcgtta ttatcggtac tcctgagtat gatcactcta ttccagctgt
    22561 tttgatgagc gctcttgctt ggttgtctta tggtatttac ccacttttga acaaaccaat
    22621 catgattaca ggtgcttctt acggtacgct tggttcatct cgtgcccaat tgcaacttcg
    22681 tcaaatcttg aatgctcctg aaatcaaggc aaatgttctt ccagatgaat tcttgctctc
    22741 acactctctt caagcattta acccaagtgg cgacttggtt gaccttgatg ttatcaagaa
    22801 attggatgcc atctttgatg acttccgtat ctttgtaaaa atcacagaaa aattacgtaa
    22861 tgcacaagaa ttacttcgca aagatgctga agactttgac tgggaaaatt tgtaagatag
    22921 gagaccaaaa agaatgaaat ttgttggact tgttggatca aactacgatc aatcatataa
    22981 ccgtaagctc ttggaattta tccgtcgcta cttcaaactc aaatttgaat tagaagttct
    23041 tgaaattgac gaagttccaa tgtttaacca agatgaaaaa tgggatgaaa gtttccaatt
    23101 acgttattta tataacaaaa ttactcgtgc agatggtgtt atcattgcta ctcctgagca
    23161 taaccacact atctcagctt cactcaaatc tgtacttgaa tggctttcat acgaagttca
    23221 tccatttgaa aacaagcctg ttatgattgt gggtgcatca tactatgacc aaggaacatc
    23281 acgtgctcaa gttcaccttc gtaaaatcct tgatgctcca ggtgttaatg cctacacgct
    23341 tccaggtaac gaattccttc ttggtaaagc taaggaagct tttgataaca acggaaatat
    23401 caccaacgaa ggcactgtta aattccttga aacttgctta gataactttg ttaaatacgt
    23461 aggagtcgtt tcgaaattga aaaaaccaaa accaatcgaa tcagaagact tggattgtgg
    23521 aaaaccaatc gctacaacca tcacagaagt tgaccctgac gatccagaat gggtagaaaa
    23581 agttgcagca ttcactggtg ctgtttctgg tgatacctat gtcaaattgg accacggtat
    23641 cctaacagtt aaccaaattg atatgttctt gaaagctatg ccatttgaat tgacatacgc
    23701 tgacgacaac aaccaattcc tctactacaa caacgctcac caagatccag acactatgtt
    23761 cgctaaacgt gtaccacctc aatcaggtag ccgtatgtcg actgttcatg gttctcttcc
    23821 accagcacgt atgaagaacg tagagtgggt tatcggaaca cttcgcaacg gaaaccaaga
    23881 atacgtccgt acgatcgttc caggttctcc tgcaggtgtt atcaacactc acaactacca
    23941 agcaatgtac tatcctgatg gatcatacgc tggtatcaat gaaatcgtct ttaacttcca
    24001 accatggctt gactggtacc taaaagagac tggtcaacgt ttggtgggtg gtagcggacc
    24061 atttgctcct gctgccggag gtcatggaga cgccgatgct acttctagcg cttctgattc
    24121 aggggatgct ggaggccacg gtggtgacgc agacgctaca gccggtgcaa gttactaatg
    24181 atagttttta ggaactatta tggttccttt tttagcgaaa aaagactagc aaacacaaac
    24241 tgctagtctc tttgttatcg tttcatctat ctttgttaaa agaaagaata catatactca
    24301 atgaaaatca aagagcaaac taggaagcta gccgcaggct gtacttaagt acggcaaggt
    24361 gaagctgacg tggtttgaat ttgattttcg aagagtatta ttatgaattt ggatcatcaa
    24421 gactacggcc atgtaatcct ttttcacgtt gtacttggcg tagtttttct ggtgtaacat
    24481 cgtttccttc ttcgtccaca attttgattc cttcaatgtg gtgacgaaca gcgcggcgat
    24541 aaccttcgat gtactcctca cgtagtttgg cttgttccac tttttcttct ggtgttaagc
    24601 cttctgtttt tttcttttta gcaagctcat tgatacgagc aatttttttc ggatccattt
    24661 cttctccttt gtaataagat aaagtccgtt tatcaaattt tatttagtgt taatttggtt
    24721 aaaacaagca aacttagctg ctttcttggt tagttgtgac aagattgcca aacgattttg
    24781 acggacagcc tgatcttcag ccattaccat agtattttca aagaaagcat caatgactgg
    24841 gctaagcgca aaaagttgtt tcaattgctg acttgcaggt cctgataaaa tgagtgtttc
    24901 tactgcttct gccaaagctt tttcttggtc attctcaaat agtgctgaat caaccgtagc
    24961 aaccccttct gccttctcgg ccaggttaaa ggcacgagaa agtgattcaa cagatggttt
    25021 aaaatcttct tccttgctta cttctacgag agcacttgct gcttccaaca tatctgccac
    25081 aacaaagttt gaacctgcaa gaactgcttc cttgatatct tttggagtag agcccatcat
    25141 cttatcaaca cgagccttga taaagtccat aacctctgct ttattttcat aagtcaaact
    25201 gtcaaatttc aatgcataaa ggctatcaat cagctcatcc atagcaatgt gccaaccaaa
    25261 ggcatccaag atacgaacca caccttgagt tgcacgacga agggcataag ggtcattaga
    25321 acctgatgga atcaatccta ctgagaagaa actcaaaatc gtatccaatt tgtctgcaat
    25381 ggctagaact gcgccgacct tgctctctgg aagttctcct tcagctgatg taggcatgta
    25441 gtgttcacga atagcagctg ccaccgctgg agtttcacca gcaagaaggg tgtatttttc
    25501 acccataatt ccttggagtt cgtcaaattc accaaccata cctgtcaaca agtcaaactt
    25561 gtaaatggct gctgcacgag caaggtcaac tgtttcatcc actgacaaac tagctttttc
    25621 tgccaaaagt acagtgattt gacccgtacg aatcatgtgt tcacgaaggg aaccaatctt
    25681 ctcatggaag gtgacattgt ttaatttttc aacaagatct gaaatcacca atttttggtc
    25741 ttcacgccag aagaattctc cgtcttccaa gcgggctacc aagacttttt catttccttt
    25801 gatgacattt ttcaaacgct ctgcgtttcc gttacgaaca gaaatgaagt ttggcaagag
    25861 ttttccatct tgatcacgaa caacaaagta acgctggtgt tccttcatag aagtcaccaa
    25921 gacttcttct ggaacttcaa ggtatttagc atcaaaactt cccatgaagg cagttgggta
    25981 ttcaaccaaa ttcaagactt cattcagcaa atccgcatca atttcgatac gtacaccatg
    26041 ttttgcctca atttccttga tttggtcaac aatcatttgc tcacgttcac atggatctgc
    26101 gattacaaac tgcttacgaa ggtcttcttc atagctcaat gctgactgaa tcttggtttc
    26161 ttgtcccaaa aaacgatggc cacgactcac acgacttccc ttgatatcaa ggaaatccaa
    26221 gtcaaactct tgctcatcca agagaacagt taaagtgtga acagggcgga tgtattcaaa
    26281 gctatttccc gcccagtgca tgctgacagg gaaagtcagt gacttcaaga catccacaat
    26341 gcctggaaca atggcttcaa ctgcttgacc aatttcttcc ttagtgacat agacatattc
    26401 ttcacccttg atttcacgga attcgatatc ttcaacagtc aaacctttcc cacggacaaa
    26461 tccttgagct gctttggtga agtttccatc actatctaag gcaattttct ttgctggacc
    26521 cttgaaatct tctgttaaat cagactgttt gtctgcaaga ccagttacac gaacagccaa
    26581 acgacgtggt gttgagaaag tttgaatggc ttcaaaagac aggcgttttc ccttgaggaa
    26641 ggctgccatt ttttcgccta gttgtttttc acttggcgta acaacatagg ctggtaattc
    26701 ttcaagaccg agttctacta ataagttttt tgtcatgttt tttcctttac attttcttca
    26761 atcttttttg atatgcacct taggtactgg ggacgtcgct aactaactct gtgagtctgt
    26821 atggaaatcc aatgctaaat ttatcaagat ttccaacaat ctcatcaaag tggatttagc
    26881 tgactgattt ttgaacctaa ggtttcaaaa atccccacat aacagtacag cggtgcatat
    26941 ccctctagca agtcttcgac ttgcctctaa cgattttaga gtacagtatt actcactatt
    27001 ctgcgtcttc tgctaaaagt ttaactcgtg tttcttcatc caaaagtggg taacctaggc
    27061 gtttgcgttc tgcaacaaag gttttggcta caacacgggc caagttacgg atacgagcga
    27121 tatagcctgc acgctctgtt acagatacgg caccacgcgc gtcaagcaga ttaaaggtat
    27181 gtgaacattt gagaacatag tcataggcag ggtgtaccaa gccttcttct aatgcacgac
    27241 cagcttcttt ttcaaactta tcaaaatttt caagcaacat ttcttggtcc gaaatttcaa
    27301 atgaatattt tgagtgctca tactcaggct ggataaagat ttctccgtat tttacaccat
    27361 cagcccactc gatatcatag acagagtcta cttcttgaat gtaagaagcc aagcgctcca
    27421 aaccataggt aacttccgca gtcacagggc tagttgccaa tccaccgact tgttggaaat
    27481 aagtgaactg agtgatttcc attccgtcaa gccaaacttc ccaaccaaga ccagctgaac
    27541 cagttgatgg gttttcccag ttgtcctcaa caaaacgaat atcgtgctcc aaaggattga
    27601 ttcccaattt ttccaaagac tcaaggtaaa gttcttggat atttgatgga gaaggcttca
    27661 tgaccacctg gaattggtgg tgttggtaga gacggttagg gttttcccca taacgaccgt
    27721 cagcaggacg acgtgatggc tctacataag ctgcattcca tggctcaggt ccgatagcac
    27781 gaaggaaagt gtaaggactc attgttcccg cacctttttc attatcataa gcctgcataa
    27841 gcatacaacc ttggtcattc caaaattgtt gcaaagtaag gatgatttcc tggaaagtca
    27901 atttcttaga cattgtttac tcctttagtt tttatatttc tttttcaatt aatttctgct
    27961 gaacaaacca atctaacaag ggaaaagttt tttctgtatt tgcccataaa tgataagaat
    28021 ctaagaccgc ttgtacacta cctaaatttt ctaccaactt atctactgtc aaaaagctgc
    28081 gccagtattc ataaaaaata cttgcatagt tcttatcata agtcgaagaa ccaaaatcat
    28141 tcaatgaatg ccaaccatac ttcttctgaa aaagttctac gagagattga ttacaaattt
    28201 tttccgcttg aaattcctct tctgtcaaga aatacttgcg actaatatat tcaaccatcc
    28261 cctcttcgaa ccagatataa gagtcataac catcaaaatc atctaaaaaa tgctccgacc
    28321 aatgagctaa ctcatgtcct acaatctgta agaggaaatt ttcagataaa gaatgatagt
    28381 gactttctat tgcttgagtt tgctcagaac actcgtagtc catcaattga tacaaataca
    28441 actctttcca aacagctaaa tcaggcgcca taaccattcg tctattattt gtataggctg
    28501 gaacagcgct ttccctaata atctgtgtag cagcattaaa atctgaccaa ataacggctt
    28561 gcggtaaatc acagactgca agttcattct ttaaaaaaga ttgataatct ttcaactttt
    28621 cagtatttct tactacaaaa tcacgaaatg tagctagttg actatcgtct tttacaagat
    28681 aaaggttgtc cacggctctc ctttctttca cacaatagac tgaataagca aaagaaccac
    28741 atctgacaat cctaggttga tttaacctag gggcgtcaga aacgcggttc caccctaatt
    28801 tattacttca ttgtttttga aaatactaca gaaagcgcca gctcattatt ttgccctact
    28861 tggctcccac tgtcccaagc tcgcttgaag aacgccataa gactttcttt cctgctgact
    28921 attatatcaa aaattagaat aatgtacaat tctttttatg attttctaga aatccacatc
    28981 atcaactcgt ggagcccccg actgaacagc agtcgttttt aaggtttctc tctcctcatg
    29041 actcagttca attccaaaac aatcaagatt agcttgaata cgagaggttg tgacagattt
    29101 tggaagtggt aaaaatcctt ctgccaagct ccaggccaag gctatctgag caaccgattt
    29161 tccgtgattt gctgcgattt cttggacttg cttgctatca aacagttctc cttgtccaaa
    29221 aggcccccaa gcttccaata aaattccctt ttcacgacag taagctacga cttcctcttg
    29281 atacacacct ggcgccaagc gaacttgatt gaccgcagga acgatagttg cagtttcaag
    29341 caaggcatcc aaatgatggg gaagaaaatt gctaacgccg atagcacgga ttttcccttc
    29401 ttgatagagg tcttccatcg ctctccaaac ttccgcattg cgagttttcc atgcgtcatt
    29461 ttctctgagc ggttttgggt tcggccaatg aatcaaatac aaatccaaat aatccaagcc
    29521 cagtttttct atagattttt ccaaagcttg acgagtttgc tcataggttt gctgactatt
    29581 ccaaagcttg gtagttacga acatttcttc acgtggaact ccgctatctt tgattgcttg
    29641 accaacactt tcttcattct gataaatcgc cgccgtatca atatgacgat aaccagcctt
    29701 caaggattct aacactgcac gataggcttc ttctccatcc ttagccttaa aagttccaaa
    29761 tcccaatact ggaatttcta ctccattatt taattgatag gtattcatat gcttctcctt
    29821 ctatatttat tcatcaatta tagcataaaa cattttttaa gtagtactat cttctgtaaa
    29881 aaataagtct gtcaaatatc taacagacct attttttctt gcttattcat cacgactata
    29941 gtacagctca tgagctttta ggcgagtatt gagcatctct ggtatggtca caaaggtata
    30001 accttgattt ttcaaatact caatgaccct tggcaaggca ttgactgtcg gactgtgaat
    30061 atcatgcatc aaaacgatag agccgttagc tacttgatgc tgaatttctg tcaaaataga
    30121 tgcttcattt ttactcttcc agtccagact atccacatcc cacatgataa agctcaaatc
    30181 caagctattg cgaatatcat ctgtaatagc accataaggt ggacgcatga gtttagaact
    30241 agaacccagc actttagtta gcacatcctc agtatcagta atctgctttt tagcttcatc
    30301 aagagagagt tgcgagagaa tcggatggct ccaactatgg tttccaacaa catgaccttc
    30361 agattttatc ctcttcacca agtcctcatt cccagaaaca tttttcccaa gcacaaagaa
    30421 agtcgcttta atatcatatt tagctagggt ctctaatacc tgcggggtcg ttgctggatt
    30481 tggaccatca tcaaaggtta gagcgacaac tttttgatat ttcttatcaa agtaagattg
    30541 gtacaaggcc gcatcttttt cgagtaagta cgaagattgg ataacatcaa agaaagcaga
    30601 tactggcaag gctatctctt ctaaattttc aaccacagga cttggataaa ggataatctg
    30661 actatccttg taatcaaaat tccatgcaga caagtcttgg tcagagaagt tttttacaat
    30721 ctgctcactc tggtcttgct ctattttttt atcctctatg aaggaggtca actcttttat
    30781 cagctgttcc ttagccttac tagcatctga aaacagttgg tcaagtgtaa aaggttgccc
    30841 atcttctgtt aagtgaacct ttcctagact ggtcttttca gtctcttcaa ccttaaaagc
    30901 aactaaatca tagatttgtt tggtcacatt acgattaacg actcccttta aacctgactc
    30961 ttcttgctct gtatagtaga aaacaagatt gtccttactt tctagcttgt ccttaacatc
    31021 ttgatttatc aactccctaa cagaggaaat cactttctcc ccttggagag gataataggc
    31081 aatcacttcg gcttgcccct gacgaaaatg ctccttctga tttccctcac tcaattgatc
    31141 atctttctct tttttgagcg attcaatctt ttgctcaaaa cttttttgct ggtagatctt
    31201 aaaagcaata aatccgccta ataggcaaat agaaattgct aaaataccaa tcaaagccaa
    31261 taatacatgt ctcgttttcc cgtgtctgcc acgtcctagt ctacttttat tcatatttat
    31321 atcataacaa atttgagcaa taatttcaat gatacaattt ggcaatccac aattcctcta
    31381 gcaagccaaa gcatcttaca tcaactccaa catccgtatc tgtagagatt atgtagtttt
    31441 ctatctatgg aatttctagt agattgaagc tagaatagta gacctatact tctaaaacat
    31501 tgttagaaat cgatttgatt gtcctgatcg atttgtcctg ttctcatttc attttactat
    31561 aaaactatga aaagctaggt catctgagaa gtaattacta tcgacaattg cgatagcgta
    31621 tactggtgcg atttgtttgt agctctggtg ggtatcacct tcacgttggc gaattttttc
    31681 taggttttga ttaacctgac tgcacagata agcccatagg cgattgatga aaaaattctg
    31741 atgatgaacc tgaatttcga tgataacttg gattccatta tctaactccg ccaagacgtc
    31801 tatactagta tagaaatcct gcgctgagta gggcatggaa ggcaagacgt gaatgttact
    31861 tccctccaaa atcgtcacat tttttgctgg caagtccagc atatcgcgga taaattgaca
    31921 aatcattagt tgggctgata cccggatgtc tgagaatcct ccttttcctc cttctattat
    31981 agcacatttt taaatctagg tttgctagat tctatgcttc tatctattta ttcggaaaag
    32041 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
    32101 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
    32161 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
    32221 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
    32281 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
    32341 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
    32401 acatgttatt ctcgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
    32461 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattacc acgagaaagc
    32521 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
    32581 tgccaaatac tcttccaaga tgcctgactt gttgactgga caaacaccaa atgtcttttc
    32641 aaaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
    32701 tcgtcttttt ggaaaagcca atgacgcgac ttaccatgct caacagcttg acaatagcat
    32761 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
    32821 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
    32881 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
    32941 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
    33001 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
    33061 tgagctacta tataccatgc gccagactgc tggcattaga tttgaggcag aaaaatgaaa
    33121 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
    33181 cccattcaaa ctcaactatt tgagcccctt cttgctggag aaaacctcct aggagtgagc
    33241 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
    33301 aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg acagattttt
    33361 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
    33421 tcaagtcaga aacgacaaat tgaacgcctt aaaaaggggc cagaaattct gattggaact
    33481 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
    33541 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagaaaaa
    33601 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
    33661 gaccaagaaa agattgtgcc gaatacacgc actattaatc tctctgacca aaaattggac
    33721 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
    33781 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
    33841 aatgccgagg aaaaactaca gtatcgtgat atattgactg tttccctcgc tagtgatgtt
    33901 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
    33961 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
    34021 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggccgtatg
    34081 ggcaaggaag gatatgttat tactctcgtc actcatccag aagaaatcaa aaaacttaaa
    34141 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
    34201 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
    34261 tcatctgctt tcaaaaagca ttctattcca tctccgatta acgatggact ttatcacctc
    34321 cttctccagt ccttgtatga catcttggag ttgattcatg acatcttcca aagttcgaaa
    34381 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tgggttcatc
    34441 tctggtgtgt atggaggaat aaaggtaaaa tcaatattag tcggaatctt taaggtactt
    34501 gatttatgcc atatagcatt gtccataacg agtaaaaaat aatcatctgg ataagcttgt
    34561 gaaagctctt ctaaaaagac gttcatccac tcagtattac atccaccagc tattaagaaa
    34621 aatgattcgc ctgtatgggg catcaacagc tccataacaa tagcgaaatt ctcgtatata
    34681 gtgactatgg acatgtggac ctactcctat tggagaccaa caagatccca gtttactgat
    34741 tctaccgaaa ccagcctcat cttggtacat caagcgaacc ttatgaaaag gtctactggt
    34801 tttaaagcgc tttcttgtct tcttgaattg agattttatt tttagacgcg acaatggttt
    34861 gagcgtctgc tttcctagga tgttctggac gtggcataat atttcgccaa ccatggtgct
    34921 tcaacagttg atagaaggca tcacgtgtgt aggaacgata taagcctgaa ataaggtatt
    34981 gtaacaaatt ctcctgcctc tgtagccttc aaatggcggg caagaaaggc tttctcttcc
    35041 tcaactgtca tatatgcatg gttacgacca ccacgtgttt cttgaaggag agagtcgagt
    35101 ccgaactcct catatttttt tacatttcgc caaatcgttg tttgattaca gtctaaaaga
    35161 tctataatct ctttataaga tttgcccatc agacgaaata gaacgatttg aaggcgttta
    35221 tgatatttag ctgtacgaaa gtcttttaaa agtgttttga tggtttggat ttcttcttta
    35281 gttgatttca tattactatt gtataatgct ttttgatttg agtctagtat tatactcttc
    35341 gaaaatctct tcaaaccgcg tcagcttcgc cttgtcgtat agaatgttac tgacttcgtc
    35401 agttctatct acaacctaaa aacagtgttt tgagcagtct gcagctaact ttctataaca
    35461 aaatgaaata agaacaagac aaatcaatca agacaatcaa atcgatttct aacaatgttt
    35521 tagaagtaga tgtgtactat tccagtttca atatattata gtttgctctt tgattttcat
    35581 tgagtattag ttcaatatct aaaaaaagag
//
LOCUS       DBEJJV010000021        35466 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.021, whole genome shotgun sequence.
ACCESSION   DBEJJV010000021 DBEJJV010000000
VERSION     DBEJJV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 35466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.021"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            96..329
                     /locus_tag="ACL3GT_001174"
     CDS             96..329
                     /locus_tag="ACL3GT_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HGR0516846.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            329..1663
                     /locus_tag="ACL3GT_001175"
     CDS             329..1663
                     /locus_tag="ACL3GT_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HGR0516847.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            1673..1927
                     /locus_tag="ACL3GT_001176"
     CDS             1673..1927
                     /locus_tag="ACL3GT_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HGR0516848.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            2023..2418
                     /locus_tag="ACL3GT_001177"
     CDS             2023..2418
                     /locus_tag="ACL3GT_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HGR0516849.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            2870..3280
                     /locus_tag="ACL3GT_001178"
     CDS             2870..3280
                     /locus_tag="ACL3GT_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HGR0516850.1"
                     /translation="MKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISER
                     TQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTY
                     FMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            3267..3824
                     /locus_tag="ACL3GT_001179"
     CDS             3267..3824
                     /locus_tag="ACL3GT_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HGR0516851.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEE"
     gene            3826..4788
                     /locus_tag="ACL3GT_001180"
     CDS             3826..4788
                     /locus_tag="ACL3GT_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="HGR0516852.1"
                     /translation="MSDVKEEVSSLSEKQLRQIDVEYAELNDSDIIERLAYLEINNNE
                     KRIVISDIEPTKEIMSVSDQIFEIQKNFQKIKNMFELFISDVSDFLSIKNKLESKELE
                     IEEADVNRFMIHLLSSGKLFVDFNENQIKQKYSKDSEEFDCIHGFASYQYDTNFAYRF
                     CHSLRNYSQHTDLPINEVKAVSPDDETVIIDFYIDLDYLLNSNFKWKKLKGELIKLNQ
                     ETSKIDAIALVKEYFNALTELYGNYNKLFLKLNHNTLVDIKSKLESLKLKHSRYYISK
                     ISKYDLKYNPGNYTMSPLAAFAEIEEIYIELSKIGLVKIVNKSN"
     gene            4800..7451
                     /locus_tag="ACL3GT_001181"
     CDS             4800..7451
                     /locus_tag="ACL3GT_001181"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HGR0516853.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            7521..8276
                     /locus_tag="ACL3GT_001182"
     CDS             7521..8276
                     /locus_tag="ACL3GT_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HGR0516854.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCFSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPCFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            8557..9360
                     /locus_tag="ACL3GT_001183"
     CDS             8557..9360
                     /locus_tag="ACL3GT_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HGR0516855.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(9475..10675)
                     /locus_tag="ACL3GT_001184"
                     /pseudo
     CDS             complement(9475..10675)
                     /locus_tag="ACL3GT_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            11223..13781
                     /locus_tag="ACL3GT_001185"
     CDS             11223..13781
                     /locus_tag="ACL3GT_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR0516856.1"
                     /translation="MERSQFEEMFQLQSSRLTTQEKLQLFTSVFAGRYDVYAKNFINE
                     QGKIQYFPSYDYGWKQLPPEKRSFQTLTNSVLKSHFRGEAAIGIFPMHLDDSCYFLVL
                     DLDEGDWKEAGLTIRRIARERQMEAHLEISRSGYGLHIWFFFEEAILSRKARLFGKKL
                     LELAMQESMQLSFDSFDRMFPNQDVLPKGGFDNLISLPFQGEAYHQGRTVFVDEQFQP
                     YEDQWRYLQEIQKISTAKVALLIQEELGKQELDKELKIVLSNMIQLEKSSVTPKTLFF
                     LKNMASFSNPEFYLKQAMRQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVSV
                     EDRRKVQRSISVEFKGELTFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKT
                     KTIILVHNKQLLDQWLDRLNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKL
                     VDVVMIQSLFKLENSQSLLDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPE
                     RKNGHEPIVFQRIGEILHTADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWI
                     ATDSARNQLILKDILAQVAEGRNILVLVNRIQQIDVFEKLLKEKEVDGCYIISGKTKV
                     RERTSLLETLEQLDKGFVLLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIH
                     RNYKDKSLVRIFDYVDIHVPYLEKMFQKRQVAYRKMDYRVIEGEEKQFVYVDSRYEKV
                     LREDLAGERQECLLILPYVHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKI
                     KVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            14080..14919
                     /gene="licT"
                     /locus_tag="ACL3GT_001186"
     CDS             14080..14919
                     /gene="licT"
                     /locus_tag="ACL3GT_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HGR0516857.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            14937..16775
                     /locus_tag="ACL3GT_001187"
     CDS             14937..16775
                     /locus_tag="ACL3GT_001187"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HGR0516858.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            16788..18203
                     /locus_tag="ACL3GT_001188"
     CDS             16788..18203
                     /locus_tag="ACL3GT_001188"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0516859.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            18795..19841
                     /gene="pheS"
                     /locus_tag="ACL3GT_001189"
     CDS             18795..19841
                     /gene="pheS"
                     /locus_tag="ACL3GT_001189"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HGR0516860.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            19841..20350
                     /locus_tag="ACL3GT_001190"
     CDS             19841..20350
                     /locus_tag="ACL3GT_001190"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0516861.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            20427..22829
                     /gene="pheT"
                     /locus_tag="ACL3GT_001191"
     CDS             20427..22829
                     /gene="pheT"
                     /locus_tag="ACL3GT_001191"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HGR0516862.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISFGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(22897..23898)
                     /locus_tag="ACL3GT_001192"
     CDS             complement(22897..23898)
                     /locus_tag="ACL3GT_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HGR0516863.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            24054..24500
                     /locus_tag="ACL3GT_001193"
                     /pseudo
     CDS             24054..24500
                     /locus_tag="ACL3GT_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            24626..24892
                     /locus_tag="ACL3GT_001194"
     CDS             24626..24892
                     /locus_tag="ACL3GT_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0516864.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            25153..27402
                     /gene="metE"
                     /locus_tag="ACL3GT_001195"
     CDS             25153..27402
                     /gene="metE"
                     /locus_tag="ACL3GT_001195"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HGR0516865.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            27466..28332
                     /gene="metF"
                     /locus_tag="ACL3GT_001196"
     CDS             27466..28332
                     /gene="metF"
                     /locus_tag="ACL3GT_001196"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HGR0516866.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            29017..31230
                     /gene="pnp"
                     /locus_tag="ACL3GT_001197"
     CDS             29017..31230
                     /gene="pnp"
                     /locus_tag="ACL3GT_001197"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HGR0516867.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQVVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDLEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            31246..31863
                     /gene="cysE"
                     /locus_tag="ACL3GT_001198"
     CDS             31246..31863
                     /gene="cysE"
                     /locus_tag="ACL3GT_001198"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HGR0516868.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            31875..32759
                     /locus_tag="ACL3GT_001199"
     CDS             31875..32759
                     /locus_tag="ACL3GT_001199"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0516869.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            32846..34189
                     /gene="cysS"
                     /locus_tag="ACL3GT_001200"
     CDS             32846..34189
                     /gene="cysS"
                     /locus_tag="ACL3GT_001200"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HGR0516870.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            34182..34568
                     /locus_tag="ACL3GT_001201"
     CDS             34182..34568
                     /locus_tag="ACL3GT_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HGR0516871.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            34572..35456
                     /locus_tag="ACL3GT_001202"
     CDS             34572..35456
                     /locus_tag="ACL3GT_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0516872.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT        10827 a         6347 c         7870 g        10422 t
ORIGIN      
        1 acaacctcaa agcactgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt attagaacat acaatggagg tcgtcatgga caatatcatc gatgtgtcaa
      121 ttcctgttgc agaagtggtg gacaagcatc cagaagtctt ggaaattcta gtggagttgg
      181 gttttaaacc ccttgccaat cccttaatgc gcaatacagt tggtcgtaaa gtatcactta
      241 aacaaggttc taagctagca ggaactccta tggacaagat tgtacgcaca ctggaagcga
      301 atggctacga agtgattgga ttagactaat ggcagatgaa cggattcatg tcctacggga
      361 tattttatta gaattgcata atggcgcctc tcctgagtcg gttcaggagc gttttgatgc
      421 gacctttgcg ggtgtctcag ccattgagat ttcccttatg gagcacgagc tgatgaactc
      481 agactcaggt gtcacctttg aagatgttat ggaactctgt gatgtccatg ccaatctttt
      541 taaaaatgct atcaaaggtg tcgaagtttc agatactgag catccaggtc acccagttcg
      601 tgtcttcaaa gaagaaaatc tggctctccg tgcggccttg attcgcattc gtagattgtt
      661 agatacctat gagtctatgg aagacgagga aatgctggcg gagatgcgta agggtttggt
      721 gcgtcagatg ggacttgtgg gtcaatttga catccattac caacgtaagg aagaactctt
      781 ctttcctatc atggagcgct atggacacga ttcacctccc aaagttatgt ggggagtgga
      841 tgatcagatt agggaactct ttcaaacagc tctaacgaca gccaagtcac taccagaagt
      901 gtcaattagc agtgtaaagg aagcttttga agcttttgcg acagagtttg aaagtatgat
      961 tttcaaggaa gagtccatcc tcctcatgat tctccttgag tcttttactc aggatgactg
     1021 gcttcagatt gcggaggaga gcgatgccta tggctatgcc atcatccgtc cgtcagagaa
     1081 atgggtgcca gaacgacaga gctttattga ggaaaagatt gcagaggagc ctgtacagct
     1141 agatacggca gaaggtcaag ttcaacaagt catagatacg ccagaaggcc attttaccat
     1201 tacctttacc cctaaggaaa aggaagctgt gctggaccgc catagtcaac aggcttttgg
     1261 taatggctat ctttcagtcg agcaggccaa tctcatcctc aatcatctcc ctatggagat
     1321 tacctttgtc aataaagaag atattttcca gtattacaat gacaatacgc cagctgatga
     1381 gatgattttc aaacggacgc cgtcccaagt cgggcgcaat gtcgaactct gtcatccgcc
     1441 taagtatttg gacaaggtca aggctatcat gaagggactt cgtgagggga ccaaggacaa
     1501 gtatgaaatg tggttcaagt ctgagtcgcg aggcaagttt gtccacatca cctatgctgc
     1561 agtacacgat gaaaacggag aattccaagg tgtactggaa tacgttcagg atatccagcc
     1621 ctaccgtgag attgatacgg actatttccg tggattagaa taaggagaaa aaatgagtta
     1681 cgaacaagaa tttatgaagg aatttgaagc ttgggtcaat acccaaatca tgattaacga
     1741 catggcgcac aaggaaagcc aaaaagttta cgaagaagac caggacgagc gtgccaaaga
     1801 tgccatgatt cgctacgaga gtcgcttgga tgcttatcag ttcttgcttg gtaagtttga
     1861 aaacttcaaa gtaggcaagg gattccatga tttgccagaa ggcttgtttg gtgagcgaaa
     1921 ttattaaacg agaaagattc ttgatttttc actaaaatct tgatagaatg tttatgttaa
     1981 atccttgtca gagcagggat tttttattga aaggatttta tcatgtcaaa gaaactcaat
     2041 cgtaaaaaac aattacgaaa tggcctccgt cgcgcaggtg ccttttcaag tactgtgact
     2101 aaggttgtag atgagacaaa aaaagtcgtg aagcgtgcag aacagtcagc aagcgcagct
     2161 ggtaaggctg tttctaaaaa agttgaacaa gcagtagaag ctaccaaaga gcaagctcaa
     2221 aaagtagcta attctgtaga agattttgca gcaaatttgg gtggacttcc acttgatcgt
     2281 gccaagactt tctatgatga aggaatcaag tctgcttcag atttcaaaaa ctggactgaa
     2341 aaagaactcc ttgacttgaa aggaatcggc ccagctacca tcaagaaatt gaaagaaaat
     2401 ggcatcaagt tcaagtaatt tttcttgagc cttgcatttc cgaaaaaatc ttgctacaat
     2461 agagccatta gaggtgtttt gaatcccaca ttttacagaa agtggcggcg ctgagaagtc
     2521 cacaaatgtg tcaaaactgg ttgctaatgg atgaaaaatt gaaataaaag tgtctttttg
     2581 ctttaaagac gagagttgcg ggcaactgcc cgaaattggg tggtaccgcg gataaacaca
     2641 ttcgtccctg tcatgtagat ggcagggctt ttcttttacg tcttagtcaa agggggttgt
     2701 tatgaagcaa tcttttaaca caagtaaact atattatggt tttcctgttt ttattttagg
     2761 atatcaagat tagaattttg gctataacat cacgacctgt agttcctctt atagtctagg
     2821 agattgggtt gtgattggag tcgttgcgag agagaatgcc gcagagtaga tcaaacagta
     2881 tcaaaaattt actgtgaata tttctgatga aacttctatg cttgcgatgg agcaggctgg
     2941 ttttatcagt catcaggaga aattggaacg tttgggagtg cattatgaaa tttctgaacg
     3001 aactcagact cctattttag acgcctgtcc acttgtttta gattgtcggg tagataggat
     3061 tgttgaggaa gacggtattt gccacatctt tgccaagatt cttgagcgac ttgttgcccc
     3121 agaactcctg gatgaaaagg gacattttaa aaatcaactg tttgccccaa cctatttcat
     3181 gggagatgga tatcagcgcg tttatcgcta tctggacaag cgtgtagata tgaagggcag
     3241 tttcatcaaa aaagcgagga agaaggatgg caagaactga gctgccagat aaaatcgaaa
     3301 cagaacgtct cgttttacga gtccgtactg tggcggatgc tgaggatatc tttgactatg
     3361 ctagtttgcc agaggtcgcc tatccagcag gttttcctcc agtcaagacc ttggaagatg
     3421 agatttatta tctggagcac attcttccgg agcgtaatca aaaggaaaat ctcccagcag
     3481 gctacgggat tgtcgtcaaa ggaacggata agatcgttgg ctctatctat ttcaaccatc
     3541 gccatgaaga tgatgtgatg gaaatcggct ataccttaca ctcagactat tgggggcgag
     3601 gttatgtgcc agaagctgcg cgtgccttga ttgacttagc ctttaaagat ttgggtcttc
     3661 acaagattga actaacttgc tttggatata accttcaaag tcaacgagtc gcggaaaagc
     3721 ttggctttac cctcgaagct cgcataagag accgaaagga tgttcaagga aaccgctgtg
     3781 acagtctgat atatggcttg ctgaagagcg agtgggagga ataagatgag cgatgtaaaa
     3841 gaggaagtaa gctctctatc tgagaagcag ttacgccaaa ttgatgttga gtatgctgaa
     3901 ttaaatgata gtgatattat cgagcgatta gcttatttag aaattaacaa caatgaaaaa
     3961 cgtattgtca tctctgatat tgaaccaacc aaggaaataa tgtcagtctc ggaccaaatt
     4021 tttgagattc aaaagaattt tcaaaaaatc aagaatatgt tcgaattgtt tatttcagat
     4081 gtctcggatt ttttaagtat taaaaataaa cttgagtcaa aggaattaga aattgaagag
     4141 gcagatgtaa atcgtttcat gattcattta ttatccagtg gaaaattgtt tgtcgatttt
     4201 aacgaaaacc aaattaaaca aaaatattcc aaagatagtg aggagtttga ttgtatacat
     4261 ggttttgcaa gctatcagta tgataccaat tttgcttatc gattttgcca ttctttgaga
     4321 aattattcgc aacatactga cttaccaata aatgaggtaa aagctgttag cccagatgat
     4381 gagactgtta taatagattt ctatattgat ttagattatc ttttaaattc caactttaaa
     4441 tggaaaaaat tgaaagggga gttgataaaa ctaaaccaag aaacatctaa gattgacgct
     4501 atagctctag tgaaagaata ctttaatgct cttacagagc tctatggtaa ttataataag
     4561 ttgtttttaa agttaaacca taatacatta gtagatatta aatcaaagtt ggaatcatta
     4621 aaattgaaac actctaggta ttatatttca aagataagca agtatgatct taaatataat
     4681 cctggaaatt atactatgtc accacttgca gcatttgctg aaattgaaga gatttatatt
     4741 gaactttcaa aaattggttt ggttaaaatt gtcaataaaa gtaattaagg agaacacaca
     4801 tgtctaaaga actttcatct aaatacaatc cagccgaggt tgaggctggt cgttaccaaa
     4861 aatggcttga tgcggatgtt ttcaagcctt caggcgatca aaaggctaag ccttattcaa
     4921 tcgtgattcc accaccaaac gtaactggga aacttcacct tggtcacgct tgggatacga
     4981 ctttgcagga tatcatcatc cgtcaaaaac gcatgcaggg ctttgatacc ctttggcttc
     5041 caggtatgga ccacgctggt attgcgactc aggctaaggt tgaggagcgc ttacgtggtg
     5101 agggtattac gcgttatgac ctaggtcgtg agtctttctt gacgaaggtc tgggaatgga
     5161 aagacgaata tgccactacc atcaaggaac aatggggcaa gatggggctt tctgtagact
     5221 attctcgtga gcgtttcact cttgacgaag gtttgtcaaa agctgttcgt aaggtctttg
     5281 tggaccttta caagaaaggc tggatctatc gtggtgagtt tatcatcaac tgggacccag
     5341 cagctcgcac agccctttct gatattgagg tgattcacaa ggatgtagaa ggtgccttct
     5401 accacatgaa ttacatgctg gaagatggtt cacgcgccct tgaagttgct acaactcgtc
     5461 ctgagactat gtttggggac gttgcggttg cggttaatcc agaagacccg cgctacaagg
     5521 acttgattgg taaaaacgtc atccttccaa tcgctaataa actcatccca atcgttggag
     5581 atgagcacgc agatcctgag tttggtactg gtgtcgtgaa aatcacacct gcccacgatc
     5641 caaatgactt cttggttggc caacgtcata acttgccaca agtcaacgtc atgaacgacg
     5701 acggaactat gaatgagctt gcctttgaat tttcaggcat ggatcgtttt gaagctcgta
     5761 aggcagtcgt tgctaagttg gaagaaatcg gtgcccttgt caaaatcgaa aaacgtgtcc
     5821 attcagtcgg tcactcagaa cggacaggtg tcgtagttga gccacgcttg tctactcaat
     5881 ggttcgtcaa gatggaccaa ttggctaaga acgccattgc caaccaagac acagaggaca
     5941 aggtcgaatt ctacccacct cgtttcaacg ataccttcct tcaatggatg gaaaatgtcc
     6001 acgactgggt tatctctcgt cagctttggt ggggtcacca aatccctgcc tggtacaatg
     6061 ctgatggtga aatgtatgtc ggcgaagaag ctccagaagg tgacggatgg actcaggacg
     6121 aagacgtctt ggatacttgg ttcagttctg ccctctggcc attttcaacc atgggctggc
     6181 ctgaagtcga ctcagaagac tttaaacgtt atttcccaac ttcaaccttg gtaacaggtt
     6241 acgacatcat cttcttctgg gtgtctcgta tgatcttcca gtcattggaa ttcacaggcc
     6301 gtcaaccatt ccaaaacgtc cttatccacg gtctcattcg tgacgagcaa ggacgcaaga
     6361 tgtctaagtc tctcggtaac gggattgacc caatggatgt tatcgagaaa tacggtgccg
     6421 atgcccttcg atggttcctt tcaaacggtt ctgcgccagg acaagacgtg cgtttctctt
     6481 atgagaaaat ggatgcttca tggaacttta ttaacaagat ttggaacatt tctcgctata
     6541 tcctcatgaa caatggaggt ttgacgctgg atgtggcgca tgacaatgtc acaaaagttg
     6601 caacaggtga ggctggtaat gtgacggacc gctggattct ccacaatctc aacgaaacca
     6661 ttgcaaaagt tactgaaaac tttgataagt tcgagtttgg tgtggctggt catatccttt
     6721 acaacttcat ttgggaagaa tttgccaact ggtatgttga gttgaccaag gaagtccttt
     6781 atagcgataa cgaagaagag aaagtcatca cacgttctgt tctactatac actttggaca
     6841 agatccttcg tctccttcac ccaatcatgc cattcgtgac agaggaaatc tttggacaaa
     6901 tctcagaagg ttctatcgtg acagctgcat acccaactgt taatctagcc tttgaagacc
     6961 ttgcggctca cactggtgtg gaaagtctca aagacttaat tcgtgctgtt cggaatgcgc
     7021 gtgcggaagt aaatgtagca ccaagcaagc ctatcaccat ccttgttaag acaagcgata
     7081 gtgacttgga agccttcttt aacagcaatg tcaactatat caaacgcttt acaaatccag
     7141 aacacttgga aatcgcatca accatccctg cacctgaact ggctatgtca agcgttatta
     7201 caggagccga aatcttcttg ccactggccg atctcctcaa tgttgaagaa gaactagctc
     7261 gtctcgacaa agaactcgct aaatggcaaa aagaactgga catggttggt aagaaactct
     7321 ctaacgaacg cttcgtcgcc aacgctaaac cagaagttgt ccaaaaagaa aaagacaaac
     7381 aagccgacta ccaagccaag tatgatgtga ccgtagcacg tattgatgag atgaagaagt
     7441 tggtgaaata aacacagaaa cacggtgatg agccgtgttt tttggtataa tgaaatcaat
     7501 atctattgat ggagaaagtg atgtccaaac accctcatta tgaattgtta aatttaattg
     7561 gctacggtct tgccaagttt gacaagcttt ttataaaaga atttcaatgc tttagcaagt
     7621 cggagtttta tcgctatgtg gtttctctgg gaattgctga aacaactgga gttgtaaaaa
     7681 atagaatgga tttatttgat ccttgttttg acaataatcg aaaaggttgg tggcagaaag
     7741 ctgaagttta tcgttttcgt aaagatttaa ttgatatgat gtttggaaat gaagatgttc
     7801 atagttatgc tgaaatagtt aaaatgttac ttgccagtga agggaagaaa acaggcataa
     7861 ccatcgttga aaaaccaata gttcgaacta aattcaaacg tctacaggaa acgggaatgg
     7921 aggctgagaa ttattttatc cttcattttg ataaagaaga aaaattccaa ggtggacagt
     7981 taaccgatgc ccgtctttat ggtgatggat atgactttca ggtagatgtc caagagtatt
     8041 cttaccttgc cgaagtaaaa ggtatccgaa aatctaaggg gcgtgtgcgt ttaactgcaa
     8101 aagaatttga aaaagtcaag gagtttcaat cggattttat tttatccttg gtcacaaatc
     8161 tagatgatat tccaaagtta gtgttaatcg ataatccttt aaaacatttt gagtttaaaa
     8221 agaatattat caaaaatgaa atcattgaat atagaagcgt agaggatttg tattagttcc
     8281 cccttaactt ttccagttga aggaacgaga agtcttgaca ggtcaacgac ttaatgaact
     8341 ggaaatcaac ggtattcgtt tgactaagtt ttaagatggc gaaatcggta ttgaatttat
     8401 cagtagtgct gattataact cttttattat ttacatgaag tatatatata tatatatcat
     8461 agaacctatt gtgaggactt tttatagttt aagccagttt ccaaccaatt tcgtgattta
     8521 ctggtaatga agaaaaacaa ttgaaaggat atttctatgc aaccaactta caacattgac
     8581 aatccaaact tgtcttatga agcgaagcgt gatttatggc ggataggttt tggtctgcag
     8641 aaagttgaca atctagtgcc atcagcgtat atggaatctt tggctgagaa acagtcccgg
     8701 ggagaactga cttatgagca ggtttatgag gatgcaacgg cttatcacca tactattgat
     8761 gcaagtacgg aagaggcaga cttggtttct ctacgtattg tagaactatt gtctcgaaga
     8821 ggctttagct ttagtcctgc gaccttactt gctattcata aggagttgtt tcaagatata
     8881 tttgaaccct ctattccggt ggggcaattt cgtcagacca atatcacaaa gaatgaacct
     8941 gttttgaatg gtgaaagtgt tgtgtactct gattactcca tgattcaaat gaccttagat
     9001 tatgatttta atcaggaaaa acaagttgca tatgcgacac taactcaggc ggatgtggtt
     9061 aaacaaatcc agcattttat ttcaggaatc tggcagattc atccatttcg cgaaggaaac
     9121 actcggacag taacggtctt tttgattcag tatcttcgtg agtttggttt tgatattgat
     9181 aatacaccat ttcagcaaca ttccaaatat tttcgtgatg ccttggtatt agataatgca
     9241 aagattttac agcgacgtcc tgagttttta acagcttttt ttgaaaatct cttgctcggt
     9301 ggtcaaaatg atttgtcttc agaaaaaatg tatctagatt tagaccttga tttttcataa
     9361 tccaaatact gagtaaacat tgaattttag gcaaaaatga agtaaatatt ctcacaagaa
     9421 aacgtatatc atcaaagttt ggctctttgt caattgtagt gggttgaaga aaagctaagt
     9481 tcgagaaagg acaaatttcg tcctttcttt tttgatgttc agagcgataa aaatccgttt
     9541 ttttgaagtt ttcaaagttt cgaaaaccaa aggcattgcg cttgataagt ttgatgagat
     9601 tattggtcgc ttccagtttg gcattagaat agtgtagttg aagggcgttg ataacctttt
     9661 ctttatcttt gaggaaggtt ttaaagacag tctgaaaaat aggatgaacc tgcttaagat
     9721 tgtcctcgat aagttcgaaa aatttctccg gttccttatt ctgaaagtga aacagcaaga
     9781 gttgatagag ctgatagtga tgtttcaagt cttgtgaata gctcaaaagc ttgtctaaaa
     9841 tctctttatt ggttaaatgc atacgaaaag tagggcgata aaaatgttta tcgctgagtt
     9901 tacggctatc ctgttgaatg agtttccagt agcgcttgat agccttgtat tcatgggatt
     9961 ttcgatgaaa ctgattcatg atttggacac gcacacgact catagcacgg ctaagatgtt
    10021 gtacaatatg aaagcgatca agaacgattt tagcattcgg gagtgaaaca gtctgggaga
    10081 ctgtttcagc ctgagcctag aaatttgaaa gcgaagctgt ttagctaagt catagtaagg
    10141 actaaacata tccatagtaa taattttgac gcgacatcgg acggctctat catatttaag
    10201 aaagtgatct cggatgacag cttgtgttct accctcaaga acagtgatga tatcgagctt
    10261 ttcaaaatct tgcgcaataa agctcatctc catctcccga ttgaaacagt cactccccgg
    10321 actgtttcaa cgtcccaaga cataatctta ggcagatttc taaaattaca ctcaaagtgg
    10381 aagtcattga gctttcgaat gacagttgaa gttgaaatgg ccagctgatg ggcaatatcg
    10441 gtcatagaaa tcttttcaat taacttttgc gcaatctttt ggttgataat acgaggaatt
    10501 tggtgatttt tcttgatgat agaagtttca gcgaccatca ttttcaagca atgatagcac
    10561 ttaaaacgac gttttctaag gagaattcta gtaggcatac cagtcgtttc aaggtaagga
    10621 attttatagg gtctttaatg tctagtaatt ttgtgataaa atgtaattgt tccatatgat
    10681 tctttctaat gagttgtttt gtcgcttttc attatagatc ttatgggact ttttttctac
    10741 ccaaaatagg ctccataata tccataggga atttacccac tacaaatatt atagagccca
    10801 aagttttagg tcgcttgata atatgcgttt tttgaatttt atagactgct cgtttaaact
    10861 ctatttactt cgtaccttct ggagcgagac ggaatattag tcacatacaa aatgagtact
    10921 attaggattt tattttcatg tacaatttca gccagtcttg ttataatcag cctataggaa
    10981 tcaaggaggt gactcttatg gctgtttttg tgtctttgga tggaattgtg gtagaagtcc
    11041 ttgatgtctt ttcttctttt aatggggata gtgagttttt cttgtgtata gcattttgaa
    11101 tctggaatag gacgccatga ctgctaaaag atttctataa attaatttga ttttcctaat
    11161 caatttgttc atatcttatt tcattccact ataaacgtct taaagacaag agtcagtttg
    11221 ttatggaacg ctctcagttc gaggagatgt tccaacttca aagtagtcgc ttgacgacgc
    11281 aagaaaaatt acaattgttt acctctgtgt ttgctggccg ttatgatgtt tatgctaaga
    11341 attttatcaa tgaacaaggg aaaattcagt attttccttc ctatgattat ggttggaagc
    11401 agttgccacc tgaaaaacgg agtttccaga cattgacgaa ctccgttttg aaatctcatt
    11461 ttcgtgggga ggcagctatc ggtatctttc ctatgcactt agatgatagc tgttattttt
    11521 tggtactgga tttggatgaa ggagattgga aagaagctgg tttaaccatt cgaagaatag
    11581 ccagggaacg ccagatggaa gcccatttag agatttctcg ttcgggttac ggactccata
    11641 tttggttctt ctttgaggaa gcgattctga gtcgaaaggc tcgcctgttt ggaaagaaac
    11701 tattagaatt ggctatgcag gaaagtatgc aactgtcctt tgattctttt gatcgcatgt
    11761 ttccaaatca ggatgttctt cctaaaggtg gatttgataa tttaatttcc cttccttttc
    11821 aaggagaagc ttatcatcaa gggcgaacgg tctttgtgga tgaacagttt cagccttatg
    11881 aagatcaatg gaggtatcta caagaaattc agaagatttc aactgctaaa gtggcactgt
    11941 taatccaaga ggagttaggc aagcaagaat tggacaagga gttgaagatc gtcttatcca
    12001 atatgatcca acttgaaaaa tcgtctgtga cacccaagac actgtttttc ttgaaaaata
    12061 tggcttcatt ttctaatccc gaattttatt taaagcaggc tatgcgacag ccaacctatc
    12121 aaattcctga gagaatgtat ttatttggag aatccgatca ttatttatgg ttgccaagag
    12181 gtttgctgta tccattgcaa gataaattta agcaggtatc tgtggaagat aggagaaagg
    12241 tacaaaggtc tattagcgtg gaatttaagg gagaactcac ttttgagcaa gagttagccc
    12301 tgtcagatat gacttctaaa gaaaatggtt tacttcatgc ggagactggt tttgggaaga
    12361 ccgttttagg tgctgctctt atctctgaac ggaaaacaaa aacaattatt ctagtccata
    12421 ataagcaact cttagaccaa tggctagatc gcttaaactg ctttttgact ttcgaagagg
    12481 aggaggctat ccgttatacg gcatcaggtc gtgaaaaggt aatcggctat gttggacagt
    12541 acggtgggac taagaaatgg ctgagtaaac tggttgatgt cgttatgatt caatctctat
    12601 ttaagttgga aaatagtcaa agtcttttgg atgagtatga gatgatgatt gtggatgagt
    12661 gtcatcatgt ctctgccttg atgtttgaaa aagttgttgc tcagtttaga gggaagtatc
    12721 tttacggttt gacggctacg cctgagcgta agaatggtca tgagcctatt gtttttcaga
    12781 gaattggtga gatactccat actgctgata agagggaaac ggattttaaa cggcaattgc
    12841 aattaagatt cacttctttt ggtcatttgg agattgaaaa gaccaaagca agtaatttta
    12901 tacagctcag tgattggatt gctacagact cagcgaggaa tcagttgatt ctcaaggata
    12961 ttctagccca agtggcagaa ggacggaata tcttggtttt agttaatcga attcaacaga
    13021 tagatgtctt tgaaaagtta ttgaaagaga aagaggttga tggctgttac attattagcg
    13081 gaaaaaccaa agtccgagaa agaacgagtt tactggagac gttagaacag ttagataaag
    13141 ggtttgtttt gttgtctact ggaaaataca ttggcgaagg ttttgactta cctcagttgg
    13201 acacgcttat cttggcagca cccttttctt ggaaaaataa tttaattcag tatgcaggtc
    13261 ggattcatag aaactacaag gataagtctt tggtgcgtat tttcgattat gtggatattc
    13321 atgttcctta tttagaaaag atgtttcaga aacgacaagt agcttatcga aagatggatt
    13381 atcgtgtcat cgagggtgag gagaaacaat tcgtttatgt tgatagtaga tatgagaagg
    13441 tgttgagaga ggacttagca ggggaaagac aggaatgtct gcttatttta ccttatgtgc
    13501 accagacaaa actgatgaat tttctaaaag aatttaggat tagtcaaatt gagatatgta
    13561 taccagagac ggttgcaaat aaagcatggc tagaccagtt gaagagccag aaaattaaag
    13621 tgtcttttac tcaatcaaaa atagtaacgc ctattctttt ggtgaataag actattgttt
    13681 ggtatggtgc aatgccatta ttagggaagg tagatgagat gaccatatta cgtttggaat
    13741 cagctagtat agtttctgaa ctagtggcag gtttacgata gagaaaattt ttaaaaattt
    13801 ctatgtatga ttttcatttt ttaatgagac tgttgacatt atcacattcg aagcacacaa
    13861 aataaaaaaa tttctacaag tacttgacaa atagattgaa atatcttaaa atgaaaatgg
    13921 ttacagagtt attaattatt taagcttcat gtcaccatta aaaattgaaa taaaaggatg
    13981 ttatcactaa tacaagtgag caggaaccta tttaatcaca tcggaagaag tttcttgatg
    14041 tttttaagta ggttcctttt attttaaaag ggaaatttta tgatcataaa acgaatacta
    14101 aaccacaatg ccgtaattgc gcaaagtaaa aaagatatcg atattcttct ttttggaagg
    14161 ggaatagctt ttggaagaaa aattggagat aaagtaaatc caattgatat tgagaaaagt
    14221 ttttttctca aaaatagaga taatatgacc cgttttacag agatgtttat taacgttcct
    14281 ttggagttgg tgtacatcac cgaaaaaata attaatctag gtaaaataac attggggaat
    14341 aattttgatg aaattatcta tattaattta acggatcata tttcttcgag catagaacgt
    14401 tataaagaag ggattattat ttcgaatccc ctacgctggg aaatctcgaa atattataaa
    14461 gaagaatttg agcttgggaa aagggcttta caaataataa aaaaagagtt aggtattgaa
    14521 cttccaattg acgaagctgc attcatagcg ctacattttg ttaatgctaa tttagaaaat
    14581 aattttcaag agtcgtataa aatcactgaa ataattatgg gaattgagaa aatcattcaa
    14641 gatttctatt gtactgagtt taaccaagat tctattgatt attatagatt cataactcat
    14701 ataaaattat ttgcccatcg cttggttgaa aatacaactt attgtgacga tgatgatgaa
    14761 gacttgttag cattaatgaa aaataaatat cctagagaat atgaatgtgg tgaacaggtg
    14821 gcaatgttta tacaaactga gtacaattat ttgctgactt ctagtgaatt agtttatttg
    14881 atggctcata ttcgtcgctt aacaaaaaat ttagattaat agaataggag aataccatga
    14941 gttataaaga taaggtacaa aaaatcctcg atgtaattgg aggtgaaaaa aatgtcaata
    15001 gagttaccca ttgtgtaaca cgtttaagat tagaattaaa agatgaaaat ttagtcaatg
    15061 atgatgatgt gaagaagata ccaggtgtaa taggtattat gaaaaagaat ggacaatatc
    15121 aaattatact tggtaatgat gtagctaatt attataaaga attcgttaaa cttggcaatt
    15181 ttgaatccga ttcagttgtt caagggcaca aagggaatat tttagaaaga atcattgagt
    15241 atatcgctgg ttccatgact ccaatcattc cagcaatgtt agggggaggt atgttgaaag
    15301 tcttggtaat cattttacca atgcttggta tattgcaatc agattctcag actattgctt
    15361 ttttgacatt ttttggggat gctccatatt atttcttacc gctgttatta gcttattctg
    15421 catcacaaaa attaaaagta acatctacat tagctatgtc tgtagcaggt gtacttctcc
    15481 atccaaattt tgttcaaatg gtgcaatcag ggaatcctct tagtttattt ggtgtacctg
    15541 tgacaccagc tagttatggt tcgtcagtcg ttccaattct tattatggtt tggttgatga
    15601 aatatattga aaaaatgatt gctaaattaa caccagctgt tactaagagt tttttgcaac
    15661 ctacgctagt attattagta tcaagctgta ttgccttagt tgtagtcggg cctattggag
    15721 taattgttgg tgaaggatta tcaaatctag ttgggcaaat gtatggtgta gctggatggc
    15781 ttacattagc tattcttggt gctattatgc catttattgt tatgactgga atgcattggg
    15841 cttttgcacc tatttttttg gcggcatcta ttgctactcc agacgtatta attcttccag
    15901 caatgttagg gtcaaactta gctcaagggg ctgcttcgat ggctgttgca ttaaagagta
    15961 aaaataataa tacaaaacaa attgcttttg cagcaggttt ctcagcctta cttgcaggga
    16021 ttaccgaacc tgcattatat ggtgtgactt taaaatataa aaaaccgctt tatgcagcta
    16081 tgattggtgg tggattagcg ggattatttg caggtcttac tagtgttaaa gcgtatctat
    16141 ttgctgtccc atctttgata gcgttgcctc aatttattta ttctgatgtg ccatcaaata
    16201 ttgtaaatgc tttaattgtg gcggttattt cggttgttat tacctttgta ttagcttata
    16261 tatttggaat cgatgaagaa gagagttcta gcaatttaga agttaaagct ggagtttcaa
    16321 ataaaaaaat gatattttct cctatatcag gagaaatcat tccgttaagc gatgtccagg
    16381 ataaaacatt ttcagataaa ctaattggag acggagtagc gattattcca agtgaaggta
    16441 aggtttatgc accatttgat gggaaaatta caaatatttt tccgactaag cacgcaattg
    16501 gattgaagag tgatgagggt gttgagttac taattcatat tggattagat actgttgagc
    16561 taaaaggtca aggttttatt agtcatgtag aagaaggaga cagagttttc aaaaatcagt
    16621 tgatttttga aatggacttg aatttaatca agactaaagg ctacgaaaca gttacaccag
    16681 taattgtaac gaataccaat gattttctag atgtattagt attacctaat aatcagacaa
    16741 tcgagcattc taaggaatta ctggtaatat tataatggag gaaagttatg accatttttc
    16801 cagatgattt tctttggggt ggagctgttg cagctaatca agtagaggga gcatataatg
    16861 aagatggtaa gggcttatca gttcaggatg tgttacccaa aggtggatta ggagaagcaa
    16921 cagaaaatcc tacagaagat aacttaaaat tgataggtat tgatttttat cataaatata
    16981 aggaagatat atccttgttt tctgaaatgg gctttaatgt ttttcgtact tctattgcat
    17041 ggagtagaat ttttccaaaa ggagatgagg aagaacctaa cgaagctggg ttgaaatatt
    17101 atgatgaatt gtttgatgaa ctacatgctc acgggataga accacttgta actctttcac
    17161 actatgagac tccattatat ttagcaagaa aatatcatgg atggattgat aggagaatga
    17221 ttcattttta tgaaaaattt gctcgaacag ttttagaaag gtataaagat aaagttaaat
    17281 attggcttac atttaacgaa gtaaactctg ttttggaatt accgtttact agtggaggaa
    17341 tagatatacc taaggagaat ctttcgaaac aagaattata tcaagctata catcatgaat
    17401 tagtcgcctc gagtttggtt acaaaaattg ctcgtgagat taattcagag tttaaggtgg
    17461 ggtgtatggt attagctatg ccagcttatc caatgactcc aaatccaaaa gatgtatggg
    17521 cgactcatga gtatgagaat ctaaattatc tattttcaga tgtgcatgtt agaggttatt
    17581 atccgaatta tgcaaaaaga tattttaagg aaaatgacat taacatagag tttgcagctg
    17641 aagatgcaga gttattaaaa aattatactg tagatttttt atcctttagc tattacatga
    17701 gtgtgactca atctgctctt ccaacacagt ataattcagg agaagggaat attattggtg
    17761 gtttagtaaa tccttattta gagtcttctg agtggggatg gcaaattgat ccaattggac
    17821 tacgtataat tttaaataga tattatgacc gttatcaaat tccattattt atagtggaaa
    17881 acggattagg tgctaaagat caactaataa aagatgaatt taataactta acagtccaag
    17941 atgattatag aattcagtat atgaaagaac atttattgca agtagctgaa gctctacaag
    18001 atggtgtgga aattatgggc tatacgtctt ggggatgtat tgactgcgtt tctatgtcca
    18061 ctgcacagct ttctaagagg tacggtctca tttatgttga tcgaaatgat gatggaaatg
    18121 gcacattcaa tcgatataag aaaatgtcct ttacttggta taaaggagtg attgaatcaa
    18181 atggagaatc cttattcaaa tagtttgttt attgatgatt agatattatc acggttaagg
    18241 cagcatctca ttaaatatga aataaagagg tttggaagac atcaaattct aaacctcttt
    18301 attttatagg gggattaatt aatttaattt tgttacagag agccgattat aaatagttaa
    18361 cttaggatag attggttata tatagtagac tgaatctaaa atagtacgaa acaattgcta
    18421 aaacatttat agaaattaat tttactttcc caatcgattt gttttcatct tatttcaatc
    18481 cgctataaag ttagataaga ataagctaac aagcagaagt aagataggtc ttgcaagaat
    18541 ggtaaaaatc tgataaacta agtggtaatt gaatagaaat ctgaaagact agtagcccaa
    18601 gggaagtata tcagggagga gagccgtgac tgcaagctct ctatatgaaa gctgggtgaa
    18661 ttcacttgcg catggattta gaaatgaagg tctgacttgt cagatgaaaa cggatggtac
    18721 cgcgtgtcaa cgctccgagt ggagtttttg gcatgtggtt ttctttttat ctacgagaga
    18781 ctgatggagg aaatatgtca actattgaag aacaattaaa agcgcttcgc gaagaaacgc
    18841 tgactagctt gaagcagatt actgctggaa atgaaaaaga gatgcaagat ttgcgtgtct
    18901 ctgtccttgg taaaaagggt tcgctcactg aaatcctcaa agggatgaaa gatgtttctg
    18961 ctgagatgcg tccaatcatc gggaaacacg tcaatgaagc tcgtgatgtc ttgacagctg
    19021 cttttgaaga aacagctaag ctcttggaag aaaagaaagt cgcggctcaa ctggctagcg
    19081 agagtatcga tgtgacgctt ccaggtcgtc cagttgcgac tggtcaccgt cacgttttga
    19141 cacaaaccag tgaagaaatc gaagatatct tcatcggtat gggttatcaa gtcgtggatg
    19201 gttttgaagt ggagcaagac tactataact ttgaacgtat gaaccttcca aaagaccacc
    19261 cagctcgtga tatgcaggat actttctata tcactgaaga aatcttgctc cgtacccaca
    19321 cgtctccagt tcaggcgcgt gctatggatg cccatgattt ttctaaaggt cctttgaaga
    19381 tgatctcgcc agggcgtgtc ttccgtcgcg atacggacga tgcgacccac agtcaccaat
    19441 tccaccaaat cgaaggcttg gtagttggga aaaatatctc tatggctgat cttcaaggaa
    19501 cgcttcagtt gattgtccaa aaaatgtttg gtgaagagcg tcaaattcgt ttgcgtccat
    19561 cttacttccc attcacagag ccatctgttg aggtggatgt ttcttgcttc aagtgtggtg
    19621 gagaaggctg taacgtatgt aagaaaacag gttggatcga aattatggga gccggtatgg
    19681 ttcacccacg tgtccttgaa atgagtggta tcgatgcgac tgtatactct ggttttgcct
    19741 ttggtcttgg acaagagcgt gtagctatgc tccgttatgg aatcaacgat atccgtggat
    19801 tctaccaagg agatgtccgc ttctcagaac agtttaaata atgattagaa aagtagaaat
    19861 ggcagatgtt gaggtgttgg ctaaaattgc caaacaagcc tttcgtgaaa cctttgcgta
    19921 tgataatacg gaagagcagt tacaggaata ctttgaagag gcttatagtc tgaaaacttt
    19981 gtcaactgag ttgggaaatc ctgactctga aacctatttc attatgcatg aggaggagat
    20041 agctggtttt ctcaaagtca actggggaag tgctcaaact gagagagaat tagaggacgc
    20101 ttttgaaatt caacgcctct atgtgctaca aaaattccaa gggtttggac taggtaagca
    20161 actgtttgaa ttcgcacttg aacttgctac aaaaaatagt ttttcttggg cttggctagg
    20221 tgtttgggag cataatacaa aagctcaagc gttttataat cgatatggtt ttgaaaaatt
    20281 tagccaacat cattttatgg ttggtcaaaa agtagatacg gattggttac tgagaaagaa
    20341 attaaggtaa gaagaggatt cttctattga aatgatagga aaggaaaaga accagtgtgg
    20401 caatggtcat tctggagaac taaattatgc ttatatctta taaatggtta aaagaattgg
    20461 tggacattga tgtgccatca caagagttgg ctgaaaaaat gtcaactaca ggaatcgagg
    20521 tagagggtgt cgaatcacca gctgctggtc tctcaaaaat tgtcgtcggt gaggtcttgt
    20581 cttgcgaaga tgtgccagag actcacctcc atgtttgtca ggttaacgtt ggcgaagaag
    20641 agcgtcagat cgtttgcggt gccccaaatg tgcgtgctgg gatcaaggtc atggtggctc
    20701 ttccaggagc tcgtatcgct gataactaca aaatcaaaaa aggaaaaatc cgtggtttgg
    20761 agtcacttgg aatgatctgt tcacttggtg aattgggaat ttctgactca gttgtgccta
    20821 aggaattcgc agatggcatc caaatcttgc ctgaagatgc cgtgccaggt gaggaagtct
    20881 tttcttacct agacttggat gatgaaatca tcgaactttc catcacacca aaccgtgcag
    20941 atgccctttc tatgtgtgga gtggctcacg aagtggcagc catctatgac aaggcagtca
    21001 actttaaaga atttactcta acagaaacta atgaagctgc ggcagatgcc ctttctgtca
    21061 gcattgagac agacaaggcg ccttactatg cagctcgtat cttggacaat gtgaccatcg
    21121 caccaagtcc acaatggttg caaaatcttc tcatgaacga aggaatccgt cccatcaata
    21181 acgtagtgga cgtgaccaac tacatcctgc tctattttgg tcaaccaatg catgcctttg
    21241 acttggataa ctttgaaggg actgacatcc gtgtgcgtga agcgcgtgct ggtgaaaaat
    21301 tggtgacctt ggacggtgaa gaacgtgact tggacgtgaa tgacctagtc atcactgtcg
    21361 cagacaagcc agtagccctt gcaggtgtca tgggtggtca agcaacagaa atctctgaaa
    21421 aatctagtcg tgttgtcctt gaagctgctg ttttcaatgg caaatctatc cgtaagacaa
    21481 gtggtcgcct gaaccttcgt tctgagtcat cttctcgctt tgaaaaagga attaatgtgg
    21541 caacagttaa tgaagccctt gatgcggcag ctagcctgat tgcggaactt gcaggtgcga
    21601 cggtgcgtaa gggcatcgtt tcagcgggtg agcttgatac ttcagatgta gaagtttctt
    21661 caacccttgc tgatgttaat cgtgtcctcg gaactgagct gtcttatgct gatgtagaag
    21721 acgtcttccg tcgtcttggc tttggtcttt ctggaaatgc agacagcttt acagtcagag
    21781 tcccacgtcg tcgttgggat atcacaatcg aagctgacct ctttgaagaa attgctcgta
    21841 tctatggtta tgaccgcttg ccaactagtc taccaaaaga cgatggtaca gcaggtgaat
    21901 tgacagccac acaaaaactc cgccgtcaag ttcgtactat tgctgaagga gcaggtttga
    21961 cagaaatcat cacctatact ctaacaactc ctgaaaaagc agttgagttt acggctcaac
    22021 caagtaacct tacggaactc atgtggccaa tgactgtgga tcgttcagtc ctccgtcaaa
    22081 atatgatttc aggtatcctt gataccgttg cctacaacgt ggctcgtaag aataaaaact
    22141 tggcccttta cgagattgga aaagtctttg aacaaacagg taatccaaaa gaagaacttc
    22201 caaatgaaat caacagtttt gcctttgcct tgacaggctt ggttgctgaa aaagatttcc
    22261 aaacagcagc agttccagtt gatttcttct atgctaaggg aatccttgaa gccctattta
    22321 ctcgtttggg actccaagta acctatacag caacatctga aatcgctagc cttcatccag
    22381 gtcgtacagc cgtgatttca ttcggtgacc aagttcttgg tttccttggc caagtgcatc
    22441 cagtcactgc caaggcttac gatattccag aaacgtatgt ggctgagctt aacctttcag
    22501 ctatcgaagc tgcgcttcag ccagcgactc catttgtaga aatcaccaaa ttcccggcag
    22561 tcagccgtga cgttgccctt ctcctcaagg cagaagtgac tcatcaagaa gttgtagatg
    22621 ctatccaagc tgccggcgtg aaacgtttga cagatatcaa actctttgac gtcttctcag
    22681 gtgagaaatt gggacttggt atgaagtcaa tggcttatag cttgaccttc caaaatccag
    22741 aagatagctt aacggacgaa gaagtcgcac gctatatgga aaaaatccaa gcatcgctcg
    22801 aagaaaaagt caatgcagaa gtgcgttaaa cgatagtatg atacaaattc cccctctagt
    22861 ttatgaacac tagaggggtg attttatata aaataattaa aatgtgattt ctgtaaaaat
    22921 acatctatga tcagagtttt gaaaacttac aatgtctaaa tctttaacat agtagtggtt
    22981 tttaggcaat aaaatatgat ctattgttgc attaaaaagt tttggacttt ggctattcca
    23041 agttcctctt tcaaaaggtg gcagtacatt taatgcgtcc ctatgagagc ttatttttgc
    23101 aagtgctcca tgacgcatag ttgcattaaa atcacctgca ataatagcct ttggatattt
    23161 tgaagccaat tgattatgaa tgatgtttaa gtcttgcttc cagatttcca ttaaacctgg
    23221 cagaggagga gcagtatgca aggcaatgat atctggtata ttttgttttc tcgaatgtaa
    23281 tacaattgtc ccgaaccgtg ttgtatgaaa agttttagct tctgtataga aaccataact
    23341 tttcttgaca atcacagtca caggagctat tccactattg gtaggtggag aagtgaaaat
    23401 atcatagttg gccatagaaa gtccaacttg atgaaacaat agtttgattc tctggttttc
    23461 ttgctcacct ctgatattgg tagctagttc agggaatata gccatatcgg cgtcaaaatg
    23521 gctaaaaatt cgctcaatat gttgtgcttc tatttgatta gcgacgttcc aagttactaa
    23581 ttttaaggtt ttagtcttat ttgatgcaga agaaagggtt ttatctgttc cgaataatag
    23641 taatatgagc gatagtaaga gcaaaatgcc agagtaaaac cgtatttgtt tatttttctt
    23701 gtaaaaagat agggaaaaaa atacgaaact taaaatagca gccatagttg cagtagctaa
    23761 ggggaaggca taaatctgtg ccaagatagg ttgggtagat agccaaatgt taagattaga
    23821 agatgggaaa aaagaataag ttataatagg gatagaaaag agaatgaccg aaagggcaga
    23881 gagaaatgtt ttaatcattg tgtgagtacc tcaatttgca atggttgctc ggagctaatg
    23941 tgactttgtg actttacttg attgatattc tttttcttgt cttcctcata gattaagtac
    24001 aacccaagta aaaaaagtcc aatttaagat tgaaatgatt aaaaggcaca gaaatgcaag
    24061 acaattatac tacaaaaggc aaacatttga caatcgatag ccgtcgctta atcgaacgat
    24121 ggaaaaaaga aggaaaatca aatagagaaa ttgcctctct acttggaaaa gctcctcaaa
    24181 ctatccatac tgaaatcaag tatgggacag tccgacaatg tcttggaaaa gggcgcttca
    24241 aagagattta ttctgccgac tacgctcaac agtcttatga aaataatcgc aagcactcgg
    24301 tcaagaaatc aagcttgact aagaaactaa aggaaaagat tctccactat cataaccaaa
    24361 aattttcgcc tgaaatgatg gtgatggcta aaggggttaa cgtgggaatt tcaaccattt
    24421 actattggat tcatcgtgga aaattggggt taagcaagca ggatctgctt tatcctagaa
    24481 aaggaaaagc gcttaagaaa taggctagca ccaactttaa acccgctggt caatctatcg
    24541 aatcataatt cgctcatttt tttaaaaata catagacgta aaaaaaagag ggttaagtga
    24601 tgaagaatag tgctattggg agtaattgga aggatgtcca tctgagctct ttagcaagga
    24661 ggaaatcctt gaaagtgata tgcgagtggc tatcatgagc gagttgattg aggctaggta
    24721 tgaacaagga atcagtcaga aaaagctgga agaagtcagt ggaataagcc agcctgtcat
    24781 agctaggatg gagacaggag agagcagtct tcagttggat acggtcttaa aagttctaac
    24841 cagtctagga aagacactag cagtcgttcc acttgaacag gggaaaagtt gactagaatc
    24901 agttatagtc ttttctaata acaggtcata gtcacttata agaattacta ataacatgtt
    24961 ttagtattct aattggaata tagctgtaaa gtaagaatta caaaggattt gagacgtttg
    25021 cttcaagtct ttttcttttg tccgaaacag atatatagtt tcaaactata tcaaacccta
    25081 attttttaca attatacaga cgctttcttt tctgttaaga tagtttcaac aacaaatttt
    25141 ggaggacaca tcatgtcaac tacaatcatc ggtttccctc gtttgggcga attccgtgaa
    25201 ttaaaattta caactgaaaa atactttaga aaagaaatct cagaagaaga acttttagca
    25261 gcagcaaaag acttgcgtgc taaacactgg aacattgtca aagaaaaagg catcactgaa
    25321 attccatcaa atgacttttc tcactatgat aacttcctag atgcggcttt ccttttcaac
    25381 gtggtgcctg catccgttca aaacttggac ttgtctgacc ttgagcgcta cttcgctttg
    25441 ggacgtggtt accagggaga aaaaggggac gttcgcgccc ttccaatgaa gaaatggttc
    25501 aacactaact accactacat cgttcctaaa tttgaaaaag acactcaagt aaaattggct
    25561 ggtcacaaga ttttcgatga gttccaagaa gcaaaagaac ttggattgaa cactcgtcct
    25621 gttcttgtag gtccattcac tttccttcaa ttgtcagact ttgaagaagg cgtgaaagca
    25681 gacgacttcg tagatagctt agtggttgct taccaagaag tttttgctaa attggctgaa
    25741 cttggtgcga ctcgcatcca attggatgaa gcggctcttg taaaagactt gacagctgaa
    25801 gaaaaagctc tcttcttgaa cctttacaac aaactcttgg ctgacaaaaa aggtcttgaa
    25861 gtcttgcttc aaacttattt cggtgatgtt cgtgacgtat acgctgacct tgtaaacttg
    25921 ccagtagatg ctatcggtct tgactttgtt gaaggtaaga aaactcttga actcgttaaa
    25981 ggtggcttcc cagctgacaa gactctctat gtaggtattg tcaatggtaa aaacatctgg
    26041 cgcaacaact acgaaaagag cttggctgtt cttgagcaaa tcccagctga aaacatcgtt
    26101 ttgacaagct cttgctcact tcttcatgtg ccatttacaa ctgctaatga agaatttgaa
    26161 ccagcactct tgaaccactt tgcctttgca gttgaaaaat tggatgaaat ccgtgacttg
    26221 gatgctatcc gcaatggtca aggttcagaa gctcttgcag ccaacaaaga actctttgcg
    26281 actgagcgtg ttggtgaaaa tgctgaactt cgtgcgcgta tcgctggctt gacagacgca
    26341 gactacactc gtttgccagc ctttgcagaa cgtgaagcta tccaagaaga agctttcaaa
    26401 cttccagctc ttccaacaac aacgattggt tcattccctc aaacaaaaga agttcgtgcc
    26461 aaacgtttgg cttaccgtaa aggtgaattg tctcaaaaag agtacgatgc tttccttgct
    26521 gaaacgattg acgaatggat caagtggcaa gaagatattg actttgatgt ccttgttcac
    26581 ggtgaatttg agcgtaatga catggttgag tacttcggtc aaaacttgtc aggatacctc
    26641 ttctctaaaa atggatgggt acaatcatac ggtatgcgtg gggtaaaacc accaatcatc
    26701 tggggtgatg tcactcgtct taaccctatc actgttaaat ggtctagcta tgcacaaagt
    26761 cgtacaaaca aacctgttaa aggtatgttg actggacctg ttaccatcct taactggtca
    26821 ttcccacgtg aagacatctc tatcaaggat tcaactcttc aaatcgccct tgctatcaag
    26881 gatgaagtac ttgaccttga agctgctggt gtgaaaatca tccaaatcga cgaggctgct
    26941 cttcgtgaaa aattgccact ccgccgtagc gactggtacg aagactacct tgactgggct
    27001 attcctgcct tccgcttggt acactcaaca gtagcgccag acacacaaat ccacactcac
    27061 atgtgttact cagaatttac agatatcatc ccagctatcg ataacatgga tgcagacgtt
    27121 atttcctttg aagctagccg ttcaaacctt gaaatcttgg acgaactcaa agcgaaaaac
    27181 ttccaaacag aagtgggacc tggggtttac gatatccact cacctcgtgt accaaatgaa
    27241 ggcgaaatcg acaacacaat cgaagccatc cttgctaaag tgccaagcaa gaaagtttgg
    27301 atcaaccctg actgtggttt gaaaacacgt ggtatcccag aaacaaaaga aagcttgatc
    27361 cgccttgttg aagcagctaa agctgcgcgt gagaaattgt aagattggat ttctctccat
    27421 acagtggttg ttcaaaaaga aatcaactag aaaaggttat tacatatgtc acgccaaaca
    27481 ccgtcactct catttgaagt gttccctcca aacccagccg tgggtaatgg taacattatt
    27541 tcagccttgc aggatatgca ggagttggct ccccatttta tcagtgtaac tgccagcaat
    27601 aataaattta atatcaagga aacgacggtt cgtttggctg actttatcca aaatgacttg
    27661 gcgattccga ccattgccca cttgccagct atttatctaa ctaaggacaa ggttgctgaa
    27721 actattgctg acttggacaa agttggggtg cagaaaatct tggctcttcg tggggatatt
    27781 attccagacg tagaaccaca aaaggatttc cgctatgcaa ccgacttgat tgagtttatc
    27841 aaggaacaag cccctcactt tgatattatt ggagcttgct atccagaagg gcatccagat
    27901 tcgccaaatc agatttcaga tattcaaaat cttaagaaga aagtggatgc aggctgttcg
    27961 agcctcgtaa ctcagctctt ctttgataat gagcgcttct atgattttca ggacaagtgt
    28021 attttggctg ggattgatgt tcccattcat gcaggaatta tgccaattct gaatcgaaat
    28081 caggctctcc gactcttgaa gacttgtgag aatatccatc ttccacgcaa atttaaagcc
    28141 atcttagaca agtatgagca tgaccctgag tcgctcagag cagcaggact tgcctatgca
    28201 gtggaccaaa tcgtggactt ggtaactcag gatgttgccg gtgtgcatct ctatacgatg
    28261 aataatgctg atacagcaaa atacatccat caagcaaccc atgccttgtt taatcaccag
    28321 tctctaggat aataaaagca aaccattctt ctcaggtgag gggaatggtt cctttttaat
    28381 ggtaaagacc tcacttttta agaaaaatat gataaaataa attctgtacg tacttgatac
    28441 aaagatgaag gtattaaata atacaatgca tttaaactgt aagatttaac gacacgagtg
    28501 agtcaaatcg atgttatttg acgagagagt tagtaaagca tttagctaat cgcccgatag
    28561 cgattagcgt gaaagcttta gatactttag tattaaacct ttctaatgat gtatcttgaa
    28621 aactgaactt gcctacaact ctgtggaaaa agataaatct ccctaggagc agtcgctccg
    28681 tcgttcgatt tcctattttc ctttgagttg cttgacggct tggtatcttg atgacttgaa
    28741 ttttggtctc atttcttagg aaaaaagata agcttcctag cactcgtcga gtgcgacgtc
    28801 accttcctat ttttctacag aaatgttcgg caagccgaac cgtccaaaat atcttgtgta
    28861 attgaacacg gccgaaaagc tgtgtaaaaa agataaactg tcttgtcttc atcgaagact
    28921 tcgtcagttt cctattttta ctttgctttt gacgtccttg gtatcttgat ctttgtaggc
    28981 aaggcgtata atttcatcaa tccaaagggg attaaaatgg caaaacaagt gtttcaaacg
    29041 acttttgcgg gtcgtgagtt aattgtagaa actggtcagg ttgctaagca agcaaatggc
    29101 tctgttgtcg tacgttacgg tgagtcaact gtcttgactg ctgccgttat gtctaagaaa
    29161 atggcaactg gggatttctt cccactccaa gtcaactacg aagaaaaaat gtatgcggct
    29221 gggaagtttc ctggtggctt tatgaaacgt gaaggacgtc cttcaacaga tgcgaccttg
    29281 acagcgcgtt tgattgaccg tccgattcgt cctatgtttg cggaaggttt ccgtaatgaa
    29341 gtccaagtca tcaatacagt gctttcttat gatgaaaatg cgtctgcacc aatggctgct
    29401 atgtttggtt catctttggc actgtctatt tcagatattc catttgacgg accaattgct
    29461 ggggtacaag tgggatatgt agatggccaa atcatcatca acccaagtca agaacaagca
    29521 gagcaatctc ttcttgaatt gacagtagct ggaaccaagc acgctatcaa catggtagag
    29581 tctggtgcta aagaattgtc agaagaaatc atgttggaag cgctccttaa agggcacgaa
    29641 gctgtcaaag aattgattgc cttccaagaa gaaatcgttg ctgctgtcgg taaagaaaaa
    29701 gcagaagtgg aattgcttca cgtggatgct gaattgcaag ctgaaatcat tgcagcctac
    29761 aacagtgacc tccaaaaggc agttcaagta gaagagaaat tggcccgtga agctgcgact
    29821 caagtagtga aagaccaagt gactgccgtt tacgaagaaa aatatgcgga ccacgaagaa
    29881 tttgaccgta ttatgcgtga tgtggctgaa atcttggaac aaatggaaca cgcagaagtg
    29941 cgacgtttaa ttacagaaga caaggtgcgt cctgatggtc gtaaggtcga tgaaatccgt
    30001 cctttggatg cggttgtcga cttccttcct cgtgtgcacg gttcaggtct cttcactcgt
    30061 ggacaaacgc aagccctttc tgtcttgacc ttggctccga tgggagaaac tcaaatcatt
    30121 gatggtttgg atctggagta caagaaacgc tttatgcacc actataactt ccctcaatat
    30181 tctgtagggg aaacaggtcg ttacggtgcg ccaggtcgtc gtgaaatcgg tcacggtgcc
    30241 cttggtgagc gtgctcttgc tcaagtcttg ccaagcttgg aagaattccc atacgctatc
    30301 cgtctagtag cagaagtttt ggaatcaaac ggttcttcat ctcaagcttc tatctgtgcg
    30361 ggaactcttg cccttatggc tggtggtgtg ccaatcaagg cgccagtagc tggtattgct
    30421 atgggactta tctcagatgg aaataactac acagtattga cagatatcca aggtttggaa
    30481 gatcactttg gagatatgga cttcaaggtt gcaggtactc gtgatgggat tacagccctt
    30541 caaatggata tcaagattca agggattact gcagaaatct tgacggaggc tcttgctcaa
    30601 gccaagaaag cgcgttttga aatccttgat gtcattgaag caaccattcc agaagttcgt
    30661 ccagaattgg ctccaactgc tccgaaaatt gatacgatca agattgatgt ggacaagatt
    30721 aagattgtca tcggtaaggg tggagaaacc atcgacaaga ttatcgctga aacaggtgtt
    30781 aagattgata tagacgaaga aggaaatgtg tctatctact ctagtgacca agatgctatt
    30841 aaccgtgcca aagaaattat tgctggtttg gttcgtgaag ccaaagtgga tgaagtttac
    30901 cgtgctaaag tcgttcgtat cgagaaattt ggtgcctttg ttaacctctt tgataagaca
    30961 gatgcccttg ttcatatctc tgagatggct tggactcgta ccaatcgtgt agaggatttg
    31021 gtagaaatcg gggatgaagt tgatgttaag gttatcaaaa ttgatgaaaa aggccgtatc
    31081 gatgcctcta tgaaggctct tctacctcgt ccgccaaaac ctgagcatga tgaaaaaggt
    31141 gaaaagtctg agcgccctca ccgcccacgt catcaaaagg atcacaaacc taagaaagaa
    31201 tttacagaaa caccaaaaga ttcagaataa gaaaaggaga aatgtatggg gtggtggcgc
    31261 gaaaccattg atattgtaaa agaaaatgat ccagcggccc gcaccacttt ggaggttttg
    31321 ctgacttatc caggtgtcaa ggccttggcg gcccaccgtc tctcgcattt tctctggaag
    31381 cacggcttca aactattagc tcgtatgtac agtcagtttt ggcgcttttg gactcagatt
    31441 gagattcatc caggagccca gattgattca ggtgttttta ttgaccatgg ttctggtctg
    31501 gtgattggag agacagcgat tgttgaaaaa ggcgttcttc tctatcacgg agtgactctc
    31561 gggggaacag ggaaagactg tggcaaacgc catccgactg tacgaaaggg agccctcata
    31621 tcagcccatg cccaagttat cgggcctgtg gaaattggtg aaaatgccaa ggtcggtgct
    31681 gcagcagttg tcgtagcaga tgtacctagt gatgtgacgg ttgtcggtat tccggccaag
    31741 attgtccgtc ttcatggtaa gaaagatgag cctgttattc acgaagtcga agaaaaacgg
    31801 gagtattatg tcaataaact cgagcaggct aaagatgcca gtcacagatc gtctggtttg
    31861 tagaggatac ctatatgatt caagcaagaa acaagttaag ccaagaggag ctatctgagg
    31921 cgaaaaaagt aattaactgt tgccaaaact atgacggtac ctatcgcgat ccctatctct
    31981 ctaacatgct taattttgac ccaaacatgc ccgccttttt cctttattat gaaaaaggca
    32041 aacttgttgg tttattaact gtctatgcag atgaccaaga tgtagaagtg acgatattgg
    32101 ttcatccagg tcatcgccgt caggggattg cgcgtgcatt gtttactagt tttgagagag
    32161 aaacagcttc tttccccatt cggtcagtca cttttcagac agaacgtatt tttttagaga
    32221 atcatcctga ctttgccagt aactggggac taatcgagga tgaagagaca gaaacttggt
    32281 taggtaagga tagaagacct tatccgttag caaatgtttc ccatcttgaa gttttgttag
    32341 cagatagttc gtatcaggat caaattagtc aattaaaatt tcaggcattt tcagaggaac
    32401 atgaatcgag agaagttgtg gatagatatg tcgctgaagc tctgaaggat ccagaaagtc
    32461 gcttatatat tttgttaaaa gacggtcagg ttattgggac ttgcacggta gatttatcga
    32521 ctaatacgaa ttacttctac ggtttagcaa tatcggaacc tgaacgtggg aaaggctatg
    32581 gaagctactt agcaaaatcc ctcgtcaacc aactaattga gcaaaatgac aaggaatttc
    32641 agattgcagt ggaagatagc aatgtaggtg ccaaacgttt gtatgaaaaa attggctttg
    32701 tcaaacagac acaggtggtt tatctgaatg agaaaggagc aagggattcc gaagtgtaga
    32761 gacattcgga ctgaaattta cttgagctct tagtttagtg atgaaactaa cagttcttgg
    32821 attttagctt tcctgattat gatttatgat taaaatctat gacaccatgt ctcgtgattt
    32881 gcgagaattt gtcccgattg aggacggcaa gatcaagatg tatgtttgtg ggccaaccgt
    32941 gtacaactat attcacgtgg gaaacgcccg ttcgacggta gcttttgata cgattcgtcg
    33001 ctattttgag taccgtgggt ataaggttgc ctatatttcc aattttacag atgtggatga
    33061 taagattatc aaccgtgcca gggaagaagg catcacacct caggaggttg cggataagta
    33121 catcgctgcc tttcgtgagg atgtgacggc cttaggcgtg aaacctgcga ctcgccatcc
    33181 gcgtgtagtg gagtttatgg cagacatcat ccgttttgtg gaagacttga tcgagaaagg
    33241 ctttgcctat gagagtcaag gggatgtcta tttccgtgta gaaaaatccc acaactatgc
    33301 taaattggct aataaaacct tggaagattt ggagctaggt gcttcaggtc gtaccgatga
    33361 agaaacggct cgtaaggaaa atcctgtaga ctttgctcta tggaaatctt ccaaaccagg
    33421 tgagatttct tgggatagtc cttggggacc tggacgtccg ggttggcata ttgagtgttc
    33481 agtcatgtcg acagagattt taggtgatac cattgatatc cacggtggtg gagctgacct
    33541 agagtttcca caccacacca atgaaattgc ccaatctgaa gctaaaacag gcaaggcttt
    33601 tgctaactac tggatgcaca atggctttgt caatatcgac aatgtcaaaa tgtctaagtc
    33661 cttgggtaac ttcattacgg tacacgatgc ccttaaaact cttgatgggc aagtacttcg
    33721 tttcttcttt gcgacccagc actaccgtaa gcctatcaac ttcacggaaa aggcagttcg
    33781 cgatgccgag accaatctca agtatctgaa gaatacttac gaacaaccat ttacaggaaa
    33841 cgtggatgcc caagagttac aaaactttaa agataagttt gtagcagcta tggatgaaga
    33901 ttttaatgct gccaacggta tcacagttgt ctttgaaatg gccaaatgga tcaactcagg
    33961 gaactatgat gcaagtgtca agcaagctct tgcagatatg ttagaaattt ttggaattgt
    34021 ctttgttgag gaagttttgg atgcagagat tgaagacttg attcaaaaac gccaagaggc
    34081 gcgtgccaat cgtgactttg agacagcaga ccaaatccgt gaccaattgg ttactcaagg
    34141 aattaagctc cttgatacca aggatggagt gaggtggaca cgtgattgat gtcaatctca
    34201 ttaacgggat tgcgctagcc tttgagggag atgcggtgta ttctatgtat attcgccgcc
    34261 acctcatcct caaaggtatg accaagccca ataaactcca ccaagaggcg accaagtacg
    34321 tgtcagccaa ggctcaggct cgtctgattg ctctcatgtt ggaggagcag atcctaacgg
    34381 aaaaagaaga agaaatctac aaacgtggcc gcaataccaa tagtcacaca aaggctaaaa
    34441 atgcagatgt cgtgacttat cgtatgtcca cgggatttga agcagttatg ggctatctcc
    34501 atatgactga gaatctggaa cgtcttgaga gtttggtttc atggtgcatc caaaaagtgg
    34561 agggctagaa catgagggca aaagaactac aagactggtt tcctgaggct cggatttcag
    34621 accaaccagt agagaaagag ggctatctca cgcttccttt agcttctcag cagtggattt
    34681 tgctggagga agctgggctc agcgagcgtg aaaagcagtt ggttgccctt ttgacccagc
    34741 aggagcaggc tcgttcgcta aacccttggt attcctatct ggttgagggc aagggacagg
    34801 caccgcaagt ttttaaaaag attcagttgg tttattgcca tctttcttat tttcagcagg
    34861 aaaatctgac ttcttggcta gatatgatgc ggactctttt tccgaattgt cagacagtgc
    34921 tacaggtcgg agctcaggat tatgttttcg tgcttcaaca agacaaatac acttctgtaa
    34981 gagatatttt gagtgatacg attgaagcgg ttgagtatga ctttggactt cgtctttcta
    35041 tcatgttggg tcaggtttgg tctcagacag gacatcaagc cctatcagac ttaatcaaag
    35101 ctgagcggga tttgttcaag acatggtggc gtcagggtca ccaaggtgtt catacttttt
    35161 ctcagctcta tctttggagt atgggagaaa gactcgtgga cttgaagcca attaaagaat
    35221 gtctacacca gatgattttg gatcaagatc agattcagga aatcattctc tctctttggg
    35281 aaaatagtgc tgttctcact aaaacagccc agcaactcta tctgcaccgc aattctctcc
    35341 aatacaagat tgataaatgg gaagagttga cagggcttca gttgaaagag ttgaccgacc
    35401 tgaccttgtg ttatcaattg attttaggtt ctttgtcaac tatagttggt ttgtaaagaa
    35461 gttaat
//
LOCUS       DBEJJV010000022        34996 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.022, whole genome shotgun sequence.
ACCESSION   DBEJJV010000022 DBEJJV010000000
VERSION     DBEJJV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.022"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(381..1361)
                     /locus_tag="ACL3GT_001203"
     CDS             complement(381..1361)
                     /locus_tag="ACL3GT_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HGR0516873.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1678..3693)
                     /gene="recG"
                     /locus_tag="ACL3GT_001204"
     CDS             complement(1678..3693)
                     /gene="recG"
                     /locus_tag="ACL3GT_001204"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HGR0516874.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLI
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLALIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3712..4815)
                     /gene="alr"
                     /locus_tag="ACL3GT_001205"
     CDS             complement(3712..4815)
                     /gene="alr"
                     /locus_tag="ACL3GT_001205"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HGR0516875.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4805..5167)
                     /gene="acpS"
                     /locus_tag="ACL3GT_001206"
     CDS             complement(4805..5167)
                     /gene="acpS"
                     /locus_tag="ACL3GT_001206"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HGR0516876.1"
                     /translation="MIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLKGR
                     RQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLSIS
                     HTDQFVTASVILEENHES"
     gene            complement(5212..6243)
                     /locus_tag="ACL3GT_001207"
     CDS             complement(5212..6243)
                     /locus_tag="ACL3GT_001207"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0516877.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6245..7276)
                     /locus_tag="ACL3GT_001208"
     CDS             complement(6245..7276)
                     /locus_tag="ACL3GT_001208"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HGR0516878.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7357..9870)
                     /gene="secA"
                     /locus_tag="ACL3GT_001209"
     CDS             complement(7357..9870)
                     /gene="secA"
                     /locus_tag="ACL3GT_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HGR0516879.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRSLKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(10016..10303)
                     /locus_tag="ACL3GT_001210"
     CDS             complement(10016..10303)
                     /locus_tag="ACL3GT_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516880.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            complement(10331..10963)
                     /locus_tag="ACL3GT_001211"
     CDS             complement(10331..10963)
                     /locus_tag="ACL3GT_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0516881.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10967..11608)
                     /locus_tag="ACL3GT_001212"
     CDS             complement(10967..11608)
                     /locus_tag="ACL3GT_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516882.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLVFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(11601..12392)
                     /locus_tag="ACL3GT_001213"
     CDS             complement(11601..12392)
                     /locus_tag="ACL3GT_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516883.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYPGLKRKLTLQVASIPCLIYLVTVLTIAIITYFLGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12414..12806)
                     /locus_tag="ACL3GT_001214"
     CDS             complement(12414..12806)
                     /locus_tag="ACL3GT_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516884.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKENEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            13133..13984
                     /locus_tag="ACL3GT_001215"
                     /note="rgg1518"
     CDS             13133..13984
                     /locus_tag="ACL3GT_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator
                     Rgg1518"
                     /protein_id="HGR0516885.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            complement(14216..14566)
                     /locus_tag="ACL3GT_001216"
     CDS             complement(14216..14566)
                     /locus_tag="ACL3GT_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516886.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLAYVFFKKMIRLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(14706..15041)
                     /locus_tag="ACL3GT_001217"
     CDS             complement(14706..15041)
                     /locus_tag="ACL3GT_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516887.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(15129..16439)
                     /gene="der"
                     /locus_tag="ACL3GT_001218"
     CDS             complement(15129..16439)
                     /gene="der"
                     /locus_tag="ACL3GT_001218"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HGR0516888.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(16453..17166)
                     /locus_tag="ACL3GT_001219"
     CDS             complement(16453..17166)
                     /locus_tag="ACL3GT_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HGR0516889.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(17163..18059)
                     /gene="dnaI"
                     /locus_tag="ACL3GT_001220"
     CDS             complement(17163..18059)
                     /gene="dnaI"
                     /locus_tag="ACL3GT_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HGR0516890.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(18060..19229)
                     /locus_tag="ACL3GT_001221"
     CDS             complement(18060..19229)
                     /locus_tag="ACL3GT_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HGR0516891.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(19230..19703)
                     /gene="nrdR"
                     /locus_tag="ACL3GT_001222"
     CDS             complement(19230..19703)
                     /gene="nrdR"
                     /locus_tag="ACL3GT_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HGR0516892.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            19843..20208
                     /locus_tag="ACL3GT_001223"
     CDS             19843..20208
                     /locus_tag="ACL3GT_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0516893.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            20213..20908
                     /locus_tag="ACL3GT_001224"
     CDS             20213..20908
                     /locus_tag="ACL3GT_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516894.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            20925..21692
                     /locus_tag="ACL3GT_001225"
     CDS             20925..21692
                     /locus_tag="ACL3GT_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516895.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(22045..23244)
                     /locus_tag="ACL3GT_001226"
     CDS             complement(22045..23244)
                     /locus_tag="ACL3GT_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516896.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(23241..24134)
                     /locus_tag="ACL3GT_001227"
     CDS             complement(23241..24134)
                     /locus_tag="ACL3GT_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516897.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            24257..24448
                     /locus_tag="ACL3GT_001228"
     CDS             24257..24448
                     /locus_tag="ACL3GT_001228"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516898.1"
                     /translation="MKIKEQTRKLAVDCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYTYGKAKLTWFEEIFEEY"
     gene            24841..25029
                     /locus_tag="ACL3GT_001229"
                     /pseudo
     CDS             24841..25029
                     /locus_tag="ACL3GT_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558115.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            25444..26061
                     /locus_tag="ACL3GT_001230"
     CDS             25444..26061
                     /locus_tag="ACL3GT_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HGR0516899.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(26381..27268)
                     /gene="scrK"
                     /locus_tag="ACL3GT_001231"
     CDS             complement(26381..27268)
                     /gene="scrK"
                     /locus_tag="ACL3GT_001231"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HGR0516900.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(27417..29300)
                     /locus_tag="ACL3GT_001232"
     CDS             complement(27417..29300)
                     /locus_tag="ACL3GT_001232"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HGR0516901.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            29677..31131
                     /locus_tag="ACL3GT_001233"
     CDS             29677..31131
                     /locus_tag="ACL3GT_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HGR0516902.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFRETGVKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRTSEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGITRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            31112..32077
                     /locus_tag="ACL3GT_001234"
     CDS             31112..32077
                     /locus_tag="ACL3GT_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0516903.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKPAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(32112..33386)
                     /locus_tag="ACL3GT_001235"
     CDS             complement(32112..33386)
                     /locus_tag="ACL3GT_001235"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HGR0516904.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(33386..34558)
                     /locus_tag="ACL3GT_001236"
     CDS             complement(33386..34558)
                     /locus_tag="ACL3GT_001236"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HGR0516905.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(34689..34937)
                     /locus_tag="ACL3GT_001237"
     CDS             complement(34689..34937)
                     /locus_tag="ACL3GT_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516906.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPISQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT        10345 a         7754 c         6522 g        10375 t
ORIGIN      
        1 aacatatata cggcaaggcg aagctgacgt ggtttaaaga gatttttgaa aagtattaac
       61 acctacagac aagcctgacg atagcaagaa ctaccctact cgataggtat cggcttttgc
      121 tttctgaaaa aaattatttt aagcaatttg acaaatctag caacaaaaaa ttctataaat
      181 ataatagatt gaaactagaa tagtacacat ttgcttctaa aacattgtta gaaatcgatt
      241 tgactgtcct gatcgttttg tcctattctt gtttcatttt actatatttc catgataaaa
      301 cgcatagtat caagtttttt taatcccctg atactatgcg tgtttgtaat ttttaagatt
      361 ttgtgcttag agtcgactcc ttattttaga tatttaaaag gaatctcact tccacagagc
      421 cagttgtaga cttggtcatt gacaaataca ttcatggctt cgtgagcata ctcaggcatg
      481 atgcgatagg ttttatcgca ggtcagacga ttataaatcg caaactgggt aatgggatag
      541 caaacatcgt cgtccaagcc cgtaatcatc ttaacctcac cttggatacg atgggcaaga
      601 tttttgacat cgatataggc aagggtcgcc atgatttcct cctctgtttc atggaagggg
      661 tcgtgaaact tgaaataacg gaaaagttcg tcgtaagcct cgctagtatt accaatctca
      721 atcacccgtc tgaagtctga caagaaggga taaatggcaa ctgttttctg aattcgagga
      781 ttgagcgctg ctgcaactag agctagagcc cctccttgtg aggcaccata gctagaaaga
      841 cgcttctcat caacctgaga cagactagca acaatttcga ccaactggta aatatccaga
      901 taaacatcct tataaaagag gtggtcccga ccttccatag caccacggat aatatgcccc
      961 ttcacggtat ttcctaaagg agaacgcaag ccgtcttgtg agtaacctga ctggccccgc
     1021 acatccatgg aaacaacacc gtaaccagct acggtgaagc ccagcatgtc ggcccagtcc
     1081 cagccacgtc ccatataacc atgaaaatgg aagattaatg gaaccttctc ctcactcttt
     1141 ggaagaacaa tgcgtgcata gacctttcct tccttgcttc cttcaaatgt taactcatag
     1201 cacttgactt gaggaatgtg gaaatctctt tcctccaagt ggtaggatgg aagtgtggaa
     1261 acatttttca cttccccatc ccagaaagca tcaaagtctt ccggaacctc atcccttcct
     1321 ctataggtct taatttcttc tagcaaagct ggatttttca tagcatgctc cttttatttt
     1381 gtaatcgtta ccacaactgt agcatatcta tgtaatcaat gcaagaaaga agggtaaata
     1441 gaaagtgaat ttagattctt tacttttagg atgatgggct gaaagtagtt ttagaaacga
     1501 aaaaagagca tttcgctctc tcttctgttt atactagttt tttgcttcct tcttttggaa
     1561 agtggtttgg taatttactt taatcgttac tgtcatatga gagtcctcgt ttctttttga
     1621 tgactttagt ataagagcca aacctaaaaa ctagcttaag ttttccttag agaaagctta
     1681 atccagatgt tctttctttt ccagatgaag ggcaatcatg cgccactctg gatcttcttg
     1741 ccaagcttct atagaactaa tgtagctagc aacctttctt gcttcttcta aaatcggaaa
     1801 atcttcgata atatcagcca cttggaactc tggaagtcct gactgtctgg ttccaaaaat
     1861 ctcaccagaa ccacgcattt tcaaatcttc ctccgcaagg acaaatccat tggtcgtttc
     1921 tgtcatgata cgcatgcggt ctttcccaga atccgtcttg ggattagcaa cgagaacagc
     1981 gtaggactgc ttgtcccccc gaccgacacg acctctaagc tggtgaagtt gactgagacc
     2041 gaagcgatcg gcatccatga taatcatgac agtcgcattg ggaacgttga ccccaacctc
     2101 aataaccgtc gtcgaaacca gaatatccgt ctttctctcc ttgaaatcct gcatgatctg
     2161 gtctttttcg tcactcttca tcctaccatg tagaagagcc acctctgcct tgcctgcaaa
     2221 atgagtcgtc aactcctctg ataaggcaat ggcatttttc aaatctagag cttctgattc
     2281 ttcaatcaaa ggagagatga cataggcttg ggaacctttt tgaatttccc cctctaacca
     2341 agtcaagacc tgaggtagtt gctcatgttt gatccagcgc gtcacaatag gcttccgacc
     2401 tgctggcatc tggtcgataa tggaaacatc catatctcca aaggctgtga tggcaagcgt
     2461 ccgtggaatg ggagtcgccg tcatcatgag gacatctgga ttgtcacctt tttcccgtaa
     2521 aatacgcctt tgccctacac caaaacggtg ctgctcatcg ataataatca aagcaagacg
     2581 agcatactcc accccatctt gtatcagagc gtgagttccg ataatcaaat cagcctcacc
     2641 cttggcaatg gtctccaaga cctctctctt ttctgcagct ttcaaggaac ctatcaagag
     2701 agccagtttc aaattgggaa aaaggttctg taaactctca aagtgttgct ctgcgaggat
     2761 ttctgttggt accattaggg cagcctgata acctgctgtc actgccgcaa acatggccaa
     2821 gccagcgact accgtttttc cactccccac atccccttgt aggagacgat tcatgtggtg
     2881 gtcggacttc atatcagtta aaatttcctg caaactcttt tcctgagctt gggtcagggc
     2941 aaaaggaaga cttactttaa ctgctgtcac tttttcctga gaccaattca gaaccagacc
     3001 acttccctga actctatttt cagacttgag catctgcagc tgcatttgga aataaaagag
     3061 ttcctcaaac tttatacggc gaagagcctg cttgtattct gccaaatcct ttggaaaatg
     3121 catagctcgg actgcctgac aacgggacat gagtttgtat ttgtctagta aagactgggg
     3181 cagattttct tctatcaaga ggtccagtcc ctgatcaaaa gccgtcttga tgaccttgac
     3241 cagactggcc tgactgattc cctgagccag acgatagaca ggctggaggt catcttctac
     3301 ctgagccaga accttcatcc cagtcagact agccttagcg cggtcccatt ttccaaagac
     3361 agcaagggtt gctcccaact ctattttatc agccagatag ggctggttaa agaaattcac
     3421 cgcaaaaacg acctctccct gcttgagact aaaacgcagg cgattgcgct tgaaaccata
     3481 atactggaca ctagcaggag tcactacctg accagaaaga actgccttct caccgtcttc
     3541 cagctccagc acctgcttgg ttttgaagtc ttcataacgg aaaggaaagt agagcaagag
     3601 atcttgcaag ttttcaattc ctagtttggc gtatttttct gctgactttg gtcccacacc
     3661 aggcaagaca tgcaagggtt gatgtagatt catgctccac tcctttcttt tctaataata
     3721 ttctctcgga atacggtcgc tgaggaggca aaccacctca tagttaatgg ttacgcggta
     3781 ggtcgctacc tgagttgcag tgatttcctt atccccattg gagccaatca aggttacctt
     3841 ggttcctagc ggataaagct taggcaatcg aatagtgatt tggtccatcg aaaccctgcc
     3901 gacaattggg caagcttggc catctaccaa gacagagaaa ttttgcatgt ctcttgtcca
     3961 tccatctgca tacccgattg gcacggtcgc gatgacttgc tcgctatccg cttgataagt
     4021 tgctccatag cccatgcaag ctccagctgg aactgtcttg acatgaacca gagcagactc
     4081 caaggtcaag gccggtatca aatcataagg caaatccaag accgctccac ttggattgag
     4141 gccatacatg gcatctccca tacgaaccgc attgaaaata gtctctacat gccaaagagt
     4201 cgttgcagaa ttgctagcat gaaccagctc tggaacttcc ttcatactag ctaaaatagt
     4261 tttaaaccgt tctaactggg cattaaaata gtcatctgat tcctcatcag cagtagcaaa
     4321 gtgggtaaag attccttcaa cacaaacacc gtgttgttgg agcaaatctt gagcctgctc
     4381 aacctcactt gcctctctaa aaccaatccg tcccatccct gaatcaatct tgaggtggac
     4441 tgtcaatcca gttaggtcca cttccttatc taagagtgct tgaatccact ccagtccagc
     4501 cactgtcaag gtgaagtcat attctttagc tagagcaaca gcttcgattt cagaaactcc
     4561 taaaatgagg attggcttgc tgagtccagc ttgtctgagt tcaatggctt catcgatatt
     4621 ggaaacgcaa aagccatcaa catcatcttg aattgccttg gcaacggcaa cagctccatg
     4681 accataagca ttggccttaa ccacagccaa cttgagcgtt ccttgaggga tatgagcccc
     4741 catttgctga atattttgtc gaatagctcc cagatgaatc agagccttgg ttggtctatg
     4801 tggactagct ttcatgattt tcctccaaaa tgacactggc tgtcacaaac tgatcggtgt
     4861 ggctgataga cagccaaatc tttcctgaaa atggtgcctg actaaaataa ggcgccccac
     4921 gttcattgtt caagacttcc aaatcctgaa aaccgagctt gctaatgccc gttcccatag
     4981 ccttggaaaa ggcctcctta gccgaccagc gaccagctaa atattctatt tgcctgcgtc
     5041 ctttgagact ggtgaagcgc tccatttcct gagcggtcag tacacgctta gcaaatcctt
     5101 catgtcgtgt aactgcgctt tctatcgaag ccaattcttc gatgtcaatt ccgtgtccaa
     5161 ctatcattct catcaaaagg agttgagatt ccccaactcc atccttttca cttattttgt
     5221 caaggtaaca taaatctctt ctaccaaggc ctctgtattt tcccaaccta ggcaagggtc
     5281 agtaatagag caaccaaaga tctctggttg gttttgacga ccatctgcta ggtaagattc
     5341 aatcataaat cctcgaaccg tctttttaat tttctcattc caatcacgat tctgcaaggt
     5401 ctggcgaaca attcgaatct gctccatata ttgcttgcct gagttatcat ggttggtgtc
     5461 aatgaggata aaaggatttt caagtcccat ggtttcatag cgttcaatgg cttggagtag
     5521 attttcatag tagtaattcg gcatataatt gccatactcg ttgactgctc cacggaggat
     5581 aacatgggcc aaaggattac ctgatgtctc aacttcctgc ccatgataaa ggaaggtttg
     5641 cttgttttga gcagcataga tggcgttaaa cataacaccc aaatttcctg aggttggatt
     5701 tttcatccct actggtgcat caatcccaga agccacaaag cggtgctctt ggtcttccac
     5761 agaacgagct ccaacggcat ggtagctgac caagtcatcc accaagatca gatttgacgg
     5821 ataaagcatc tcatctgccg ttgtcaaacc agtctctgta atcacgcggt agtgcaactg
     5881 gcgcacagcc tgcaagccat taatcaggct tggagcctta gaagtatctg gctggtgaac
     5941 taatccttta tagccgtctc cattggtacg aggcttagca gtatacacgc gcatgaccat
     6001 gaaaatctta tccgctacct tcttttgcaa ggcagataaa cggcgagcat attccaagac
     6061 cgcctcttca ttatcagaag agcaaggacc aatcaccaag agaatacggt catcttcccc
     6121 tgaaataata tctgccaatt ccctgtcacg gctttccttg agtctcaagg cttccgcaga
     6181 caattgggtt tcagccttga tgacttccat atcgatttct tgaccttttt caataaatgc
     6241 catcttattc tcctaacgtt ttgtaaattt ctctgacaag agcttctgtg ttatcccaac
     6301 ccaggcaagg gtctgtgata gacttaccaa atacttctgg ctcattttgt cgaccatctt
     6361 ccagataaga ctcaatcata aaaccacgaa cgaactgctt aattttttca ttccaagcac
     6421 ggttaatcaa ggtctggcgg acaattcgga tctgttcaat atactgctta ccagaattgt
     6481 catgattggt atcaatgatg ataaaaggat tttccaagcc cattttctca tactgggcaa
     6541 tggtatcaat taaattgtca taatagtagt tgggaatatt ttttccatac tcattaagag
     6601 caccacgaag aatagcgtgt gaaagcgggt tcccagttgt ttctacttct tttcctaaga
     6661 aaaggaaact ttgtttgttt tgagcagcat aaatcccatt aaacatgaca ttgagatttc
     6721 cagaggttgg atttttaaaa ccagtagaaa atcctgcccc acttgccaca aagcggtgtt
     6781 gctggtcttc aactgaacgg gcaccaactg ccatgtaaga aatcaaatca tctacaagcg
     6841 gaaggttttc aggataaagc atttcatcag cagttgtcat ccctgtttct gtgatgacac
     6901 gatagtgaag atggcgaacg gctttgattc cattgataag actaggcgct tctgtcgcgt
     6961 taggctggtg aatcaagccc ttatagccat ctccgttggt acggggtttg gcagtataaa
     7021 cacgcataac cataaagata cgatctgcca cttcttcttg taggactgcc aaacgcttag
     7081 cgtattcaag gacagcttct tcgttgtcag atgagcatgg cccgattacc aagagaattc
     7141 gctggtcttc tccacgtata atggcttcta gctcttgatc tcgctgtgat ttcctctcca
     7201 aagcctgacc ttctaatttt gacaaggcac gaacttcttc tatatttatt ttagagcttt
     7261 ttgctgtaaa taccataact catctcctta taaagcaaac ggatacccag taaaaattta
     7321 cttttcacaa gatatccgcc tctaaactat ctcattttat tgtcttttac cgtgacagtt
     7381 tttaaatttc ttaccagaac cacatgggca aagttcattg cgtccaatct ggctcaaatc
     7441 caaatcttct ggcatacttg cttggtgagc agcgatattg cgagtcgctg ttgtactgat
     7501 atgacgttct gcctgtggtc tttcttgttc atgaatttgt gctttcatca tcaagcgtgt
     7561 cacatcaaac tcaatcgaac caatcatatc attaaacata cggaaacctt ctgcctgata
     7621 ctcaacaaca gggttgttct gagcatagcc acgaagtcca accgcgttac gcaattgatc
     7681 aagggcatcg atatgatctg tccacttgtt atccaccact cgtagaatca aaactttttg
     7741 gaattcttta actgcttctt catcgcgtag ttttgaaacc tgactatcgt aaaccttcaa
     7801 ggaacgttgg aaaagctctt ccttgatggc cttatcagac aagcctgaca agtcttccat
     7861 cgtaatagaa tcttcaggaa gcaagttgta cttagcaaag ttcaaaattg cctctagttt
     7921 ttcatcttgt ttggcacgcg catgaccatc aacgacacgt tcaatcgtgc gtttgatcat
     7981 agactgaatt tcaggtgcca agtcacgatc tgcagtgatg acatcgtaac gttgagcata
     8041 gataatctca cgttgttcac gcatgacatc atcgtattga aggacttgtt tacgggtatc
     8101 gtagttattt ccttcgacac gtttctgagc tgcttcaacc tgacgcgtca acatgcgaga
     8161 ctcaatggcc tcttcagaca tgttgagacg ttcaaagatt cccttcaagc gttcagaacc
     8221 aaaacgtttc atcaaatcat cttcaagaga taggtagaat tgtgactcac ctggatctcc
     8281 ttgacgacct gaacgtccac gaagctggtt atcgatacga cgactttcat gacgttctgt
     8341 accaataaca caaagtcctc caagttcacg aacaccttca ccaagcttga tgtcggtacc
     8401 acgacccgcc atgttggttg cgatggtaac ggcaccacgt tgaccagcat tcatgatgat
     8461 ttgggcttct ctatagtggt ttttggcatt caagacttcg tgaggaacac cagctgcaac
     8521 caatttctta gaaatgtagt cactagtttc aaccgctact gtaccaacca agacaggttg
     8581 acccttttgg taacgagcct taacgtcttc gacaaccgct ttaaacttag attcgatact
     8641 tgcataaaga aggtctgagt ggtcaatacg ttgaacagga cggtttgttg ggattggaat
     8701 aacacgaatg ttgtagattt cacgaaattc ttcttcctca gtcttacctg tacccgtcat
     8761 accagacaat tttttgtaca tacggaaaag gttttggtac gtgattgagg cagatgtctt
     8821 ggtttcatcc tggattggca caccttcttt ggcttcaata gcttggtgca atccatcaga
     8881 ataacgacga ccttccatgg tacgacctgt aaattggtcg acaatcaaga tttcttgctc
     8941 ttcgctcacc acatagtcaa tatcgagaag catgatgtag ttggcacgaa gggcgttatc
     9001 gataaagtgg gtcaaagcca cgttttcgat gtcatagagg ttttcaagtt tgaagtagct
     9061 ttcagccctg tcaatccctg aatcagacaa accaatagtc ttagactgca catcgatgat
     9121 gtagtcatct ttgttcaaag attttacata gtggtctgcc atgtgataca actgactggt
     9181 ttcaaccgca ttggcacctg atacaatcaa aggtgtacga gcctcgtcaa tcaagataga
     9241 gtcaacctca tcgaccaagg catagttaag cggacgttgt accatgtttt cagcgcgaac
     9301 gaccatgttg tcacgaaggt agtcaaatcc gatttctgag ttagttgagt aagtaatatc
     9361 acactcatag gcttcttttt tctccattgg agatttggta gccaagttaa tccctactga
     9421 caaaccaagc caagagtaca attcacccat ctcagtcgcg tcacgttctg acaggtattc
     9481 attaaccgta actacgtgaa cccctttacc tgaaagggca ttgaggtata ccggcatggt
     9541 cgcagttaag gttttccctt cccctgtacg catctctggc acgtcaccat ggtgaagaac
     9601 aatccccccc atgacctgaa ccttataagg gaagagacct aggacacgtt tggcaccttc
     9661 acggacaacc gcaaatgctt cgtaaagcaa tgaatccagt gattctccat tttgataacg
     9721 ttccttaaat tcaactgttt ttgcttttag ttggtcgtca gtcaaagcag ccatttggtc
     9781 ttcgtatttg aaaaccttgt cagccatctt ttccagacga cggatttctc ctttatcatt
     9841 ttcgataatt gtttttaaaa tattagccat gtttttcctt actttaaatt ccgaatattt
     9901 tagaatgttc ctttaatttt agcacaatta ctgattattt tcaaggaaga atccccattt
     9961 tgaaaaggaa aaagaggtta gttttcaagc taacctctcc gacttttatg actgtttaat
    10021 tgccaaaaat cggcaaaatg gcaaatgtga taaataagtt aatccaaaga gaaagacagc
    10081 aaatcagtcc aaaaacaaag agactgactt tcttggacag caaggccatg agaatggaca
    10141 gaattccaaa agctagcaag attttctgta tgatgaagat gtcaatcctt acccccagaa
    10201 tcgctctatc ccaagggata aagaagaaag acagccagat cagcagaact aaaccaatat
    10261 aaaccttgga atagcgtgta ataaatgatt ttagatgtgc cataagccat ctcctaggat
    10321 tgtatatcct ttacatttgt atatgtccat tttcgacaac taatacatct gtacaaaggt
    10381 ctgaaatatc ttccgatatg tgcgacgtca ggataaccag accattttct tttttcaggt
    10441 aagataaaat gacctgtttg gttaacctca cactcttctc atccaaagca ttcataggtt
    10501 catcgagaaa gagtatagaa ggagaggaaa taaaggcttg aatcaaggcc attttttgct
    10561 ttgttcccaa ggataaatga cggtattcaa cgtcttcaaa ttcctgtaaa tcatagtatt
    10621 gaatccaata ggcaattctt ttttccgtaa ctttagatga aaaatacctt aacagttcca
    10681 aattttctct cagggataaa tgagataaaa actcgacttt ttcaattaaa attcctgcat
    10741 cctgaatata atgatttttt atcccgtaga ctttcccgtc ttgaagaact tttcctttgt
    10801 caagcttaat atagccagca agtaccttta aaagaaccgt cttgccagat ccattatcac
    10861 ctttaagtcc ataaattttt cctgattgaa acaccaaatt caactgattt aaaataggtc
    10921 ttttcccata aattttctgt ccatttataa tttcaagtct catcgtttat cctttcttaa
    10981 atttctcttc caagcgacta acaatcaaca taactaataa acttaagagt agtaaataca
    11041 ctgttacaat atgatccatc atccattctt gtcccacaaa tactaaaaaa tagagaaaaa
    11101 aggaaaaacc agcgcccgca ctaatcagtg ctatcagata agacagtagt aagtacaaca
    11161 tcattaactg agcaagtaaa aagaaaagtg cgactgtttt gaaatgaatt cctagcggaa
    11221 gtaaaccaag gaaccagaca aacaaatctt gagtaaaaaa tttagaaatg acaaccaatc
    11281 gtttccttgt ataatcgaaa aaggagcttg attgatagcg aatcaagtga tggtaatggt
    11341 ctgccaaatc actttcaagt aaaatgacag agagccatcc taccatgaaa agcgaaaggt
    11401 ttaacaagag tttggggatt tctaaattcg cttcagaata gtcattatag gaaaaaattg
    11461 aaatcaattc tctcttgaaa aagataacag catcctgctt ttgaaccgct gttgacaata
    11521 gatggtttat caaaatcatc atcagaacta tacgaagtag taaaacaatc tttctcttta
    11581 gcaaaatatt gttaaaattc ttaaacatta tcttcatatt tttcaagcac catgtaaggg
    11641 acaatataaa ggatataagg agtaaagagt ttcatcaaac ttacatcccc atagctagct
    11701 tgcatcaaac tcgtcatagg aaccatatag taaggcaagg cactatagag cagcatagaa
    11761 ccaagccaaa gaaacatcaa ataggtgatt gccgaacgag tcacattccc cacataatca
    11821 actatttgta aaaaatagat tgcattgatg aaaataccga ttagcaggac acaagtaaag
    11881 aacaaatagc tttttatctc tccatctagg agtctttgta aaccacttcc atcagaaaat
    11941 agagaattcc atccaagagg agaaaaagtc ccaaggaaat aggttataat tgcaattgtc
    12001 agcacagtca ctaaatatat caaacaaggg atacttgcaa cttgcaaagt caactttctt
    12061 tttaaccctg gatagctcac ttctcttcca atactcaatc gtaaaacttt atttttcagc
    12121 tcaatatatt gaaaacctag caaaacaatg atgattggaa taataaatga ttgataaaaa
    12181 cctagattga actggagaat acgaaaatct aatgctgatt ttaataagtc atttttaatt
    12241 gcttgtccat cgaatttagc tagatcgggc gcatgaatat caaaaaagaa ataagtcatc
    12301 aaaacgtcac gataaaccaa agcaagaaaa agcaaagtaa gcaagacata aacaaattta
    12361 tgccttgcca aagttaagag aggaatcttc ataaattata cctactttac gaattaattt
    12421 ggtgaccaac tacctgaaat ggcagctgat aaatcccacc aattttgtct tgccatatct
    12481 gctgcataaa catagccaac cgttgcccaa ttaccatgag ttgaacgagt accacaggtt
    12541 gttaacgatt ctccactacg agcttctcca ttagaattta ctatacgatg cttaacagtc
    12601 atgggatgta aatttctaca aggatttaag ttcatgatat attccgcacc ttcattttct
    12661 ttagtcaaat aacctgttct cttataactg gtcgtaataa caaaattact aaaagcacct
    12721 atctgatttg cttctacgaa agtagttcca acagcactta tcattaaaac aggaataacc
    12781 attttcaata atttcttaat tttcattttt tctgtttcct ttcatttttt attcaagaag
    12841 attccttata acttctattt taaatataga cttattctaa acgatggtat atcatacaaa
    12901 ttcctccttt acttattata tatagactct aatttcttta tccccaaaac catgtttcaa
    12961 accagataag ttgaatccaa ctccaaatca aaaatccaga gtttttcggt aaattcttca
    13021 aatatttttt aaagcccatg actttttccc tcctttttga tataataata ccaccttttt
    13081 ctacgttttt tataaatgta gaaaatattc acatttacct aggaggaaca atatgagatg
    13141 ggattatgga caaattttta aagaaattcg aaagtcaaaa ggattgaccc aacaagatgt
    13201 atgtggacaa gtcatacatc gaacaactct aacaaatatt gaacacggta aagttattcc
    13261 cagttttgaa aacatggtat ttcttcttga acaaattgat atgagcttgg cagaattcaa
    13321 gtatatatgc aacgaatacc atcctagtaa aaggcgagat attattgtag agagccaaaa
    13381 tccgtctact tttcaagata ctagaaaaat ggttgaactc actgagaaat gtcaaaaata
    13441 tcttaagaca catcacgatg ttcctattca aaatatctat cgtcatacaa aaattgtcac
    13501 agagttacga actaaaggat tcaaaaacaa ccacgtcttg aaagatttgt atgaagaaat
    13561 ttgggactat cttgaaccta tggatacatg gtacattagt gatttgaaat tgcttggaac
    13621 cattctcttt ttctttcctt ctgaaaatct tccccttctt attgatagaa ttatgaaaac
    13681 catcgagaaa tataaatact tccgagaaac aaaagcattt ttatcatctt ttttagccaa
    13741 tctctccact gtatattttc aacatcattt attcaaagaa tgtgaaacaa tcaccctaca
    13801 acttttggta ttagcagaag aattaaaaat atacgatatt cttggattct ctcaagtacg
    13861 cttgggaata ctacaacata actccgattt gattgataaa ggaataactt tattacgact
    13921 aaccaaagaa gaggcattag ttaaaatact cgaaaaagaa attaatgatt tttcaaacct
    13981 ataatttgta ataactctca tcattttatt atagtagatt gtaatagaat gtaatagaat
    14041 gtgaacgaat caattagggg atctaaagca ttttatacca atgttttata agttgtattg
    14101 tattattcca tattcaatcc actatacaag atgaatattt ctctcaagtt tcataatcaa
    14161 aataaaaatg actgtatcta tagctccata aacaaatcat agatacagtc attttttagt
    14221 tcctacacct tcctttatgc acacctttag atttccctag ttcccgcctc aagcgaatca
    14281 tttttttgaa aaagacatag gctaaccaat cactagcaaa agcgataagt agtaataata
    14341 gccaaatacc ccataacttg atatctgtca aatttctcaa gacgatattg aaaaacagaa
    14401 ctgaaaaaac tgtccaagca aggctaaaaa gagcatagag ggtgatgtaa atccagtaaa
    14461 aatagtaaaa aattgggaaa aatttacttt ctctattatc cttgtcaatc cagctgaaaa
    14521 agtaaaaaca gggtaataag attatcattt taaacaagtg ttccatcaca agcctccttt
    14581 tttaaattgt tttctttagt ttcgttctat taaatgttat taccaatata aaccttggaa
    14641 tagcgtgtaa taaatgattt tagaggtacc ataagccacc tcctacaaat agaaaccgat
    14701 ataaatcaat gccttccacc cttagacttc cctagttcct gtctcaagcg aaacatttct
    14761 ttgaaacagg aataagttaa ccaattcata ccaatagcta gcagaataaa aagaaaccaa
    14821 atgccccata acttgatatc tgtcacattt ctcaagacgg tattgaaaaa cagaactgaa
    14881 acaactgtcc aagcaaggct aaaaagagaa tagaagggga tgtaaaacca gtaaaaataa
    14941 taaaaaattg gaaaaaactt actatttctg ttggcctttt caatccagtt atcaaaataa
    15001 aagtacggtg ctaaaagtaa gaatttaaac aaatgttcca tcaccgacat cccccttctt
    15061 ttgatagcgt tttctattat tttattatat caaaaaaatc cggaactgtc attccagatt
    15121 ctactttttt atttgcgttt tcttgcgatg agatgaatcg gtgttccctc aaaaacaaag
    15181 gccttgcgga tttgattttc caagaaacgc aggtaagaaa agtgcatgag ttcttcttca
    15241 ttgacaaaga tgacaaaggt tggtggtttg gttgccactt gggtcgcata gaaaatcttg
    15301 agacgttttc ctttgtctgt cggtgttggg ttgatggcaa tggcatccat gatgacatcg
    15361 ttcaagacag ctgatggaat acgtgtattt tgactttcgc tgatttgctt aatcatctca
    15421 ggaagtttgt ggagacgttg cttggttaaa gctgatacaa agataatcgg tgcgtaaggc
    15481 aggtattgga actgctcacg gatatcttct tcccagtttt tcatagtgtg gttatctttt
    15541 tcaagcgtat cccacttgtt gaccacgata atcatccctt taccagcttc atgagcaaat
    15601 ccagcgatac gcttgtcgta ttcacgaatc ccctcttccg cattgatgac cattaagacc
    15661 acatctgaac ggtcaatagc acgcatggca cgcatgacag agtacttctc agtattttca
    15721 taaaccttac cagacttacg cataccagcc gtatcaatca tggtaaactc ttgaccatct
    15781 gtatctgtaa agtgggtatc aatagcgtca cgagttgttc cagcaacagg actggcaatg
    15841 acacggtctt ctcccaagat agcattaatc aagcttgatt ttccaacgtt aggacgacca
    15901 atcaagctaa acttaatgac atctggattt tcttcttcat attcatttgg aaggttttcc
    15961 acaatcgcat ctagtacatc ccctgtaccg ataccatgga cagatgagat aggcagtggt
    16021 tcacccaaac cgagagcata gaaatcatag atatcatttc tcatctcagg gttgtccacc
    16081 ttgttgactg cgaggataac tggtttgtgg gtcttataaa gcttacgagc tacgtattcg
    16141 tctgcatcag taattccttc cttaccagac acgacaaaaa cgataacatc tgcttcttcc
    16201 atggcaattt ctgcctggtg cttgatttgt tccatgaaag gagcatcgac atcatcaatt
    16261 cctcctgtat caatcatgct aaaagaacga ttgagccact cacccgttgc ataaatacgg
    16321 tcacgtgtca ctccttcgac atcttctaca atggagattc gctcaccagc gatccgatta
    16381 aatagggttg atttcccaac attgggacgt cctacaatgg caatagttgg tagggccata
    16441 atttctcact ttctacaata atttcttctg ttcaagattt tttctagttg agcttggttc
    16501 agcttgacca aactgttctg ctaggcgctg actccagctt gtggtcgcac gcgccccagc
    16561 atagtcagcc tgaacacggt cataagcttg gattgcctca gttgactgtt cttggtattc
    16621 ttcctcaaag acaacattct ctagtggcag tctcggtttc atatcatgat gttgatttgg
    16681 cacacccagt gccatcccaa agacagaata ggtgtagtca ggtaggttaa agagctctgc
    16741 cacttcttca gacttgtatc gaaccaaacc gataatcaca ccaccatagc ccaagctttc
    16801 agctgccaac aaggcgtttt gtccagcaag agctgcatcg accgaactaa tcaagagacc
    16861 ttccacacct tggggttgga aggtgtcggt atgaagtctg gctccctttt ctgctcggtt
    16921 caaatctccg acaaagagaa ggaaaacagc agactggcga atggcttctt gaggtaccaa
    16981 ttcatacaag gcatctttct tctcttgact tcgtaccaca atcacagagt aggattggaa
    17041 attcttccaa gatgatgcca tctgggctgc tgtcaaaatc tcatttaagt ctacttgggg
    17101 aatttcttgc tctttaaacc tgcgcactga agtatgagcc ttcatcaatt taatggtttc
    17161 tgtcatcgac ggtttactcc ttctaaacga gtctcctcag ccaaataacg gatgcgttcc
    17221 atgacccgtc tggcttccca ggtttcgtca tttccatgtt tcactttcgc aaaatgcttc
    17281 tccaaatctt caaagttgaa gttggatgtg aaaaaggtcg gtaaattttc ctgcatccga
    17341 tattggagaa tgacctgcag gatttcatca cgcacccaag cggtggattg ctcggcgcca
    17401 atatcatcta aaatcaggac ctcagacagc ttaatctcat ccaccaaggt cttaacattg
    17461 ccatcactga tagcattttt gacatcaatg acaaagctag gatagtggag gagagttgat
    17521 gaaacaccac gtttttctga taaatcatga gctaaggccg ccaccatgaa acttttaccc
    17581 acaccaaagt ctccatataa gtaaagacct tttcgaatag ctggatattg ctccacgaag
    17641 gctagtagct tttcaaaaac tggtaagcgc cccaaatcat ccaagtcaac ttgagccaaa
    17701 ctagctttct tgagactggc tggtagattg attaacttga gacggttctt aatagccgct
    17761 tctttttcag ccgcgattag ctcaggagtt tcttcatatg aaacatctgc atagccatga
    17821 ttcttaacca aaatcggctt gtagcctttg gcaatataat ccgtatcccc acggagaaac
    17881 ttgtcacgct cggtgatgta ctgattaaac ttggagatac tgcgatttaa ttcctctgga
    17941 gtcaaggatt cttgctggat aaaagccgca acatcagggt ccttcatgat tttctggacc
    18001 aaatcttgat aataaaaacg gctgggttga cgtttgagta cgtctccgac actttccatc
    18061 taatctcctc ctttttctaa tcgagctaat agttcttgct tcttacgttc tagttccaga
    18121 cgagtttcct cgctggtttc attcttatat tcaggattac tccatttagg aacattggtt
    18181 tttactgggg cagtctgatt ctgtttttgt gtttttgctt tctgtcctcg ctcacggatg
    18241 cgcaagactg ccttttctgc cgaatgaatc ttttgatagg catagtcatt ggctaccttc
    18301 atggcatatt tctcattgat atttgccgaa tcgaccttat taaaggtcaa taaaagaatg
    18361 atattgatga cttcgtccag caagcccaag ccagccatct gttgcaagag ttctctttct
    18421 gtttgggtaa tggttccctt gcgtgtttgc ttgatttctg ccaagaactg cagggcagtt
    18481 ttacttttgg cttctttgat aatggttgtt tccttaagac taaagtcaga ggaaactggt
    18541 ttttgagcaa ttttttcacg catgcgtttg gttgaaataa cctgagaaac agctgttgac
    18601 ttggccaatt gataggtttc aaaccaagtc catttcttct cctcggcaat agcaaagagg
    18661 tttaagacat cggactgctc atccgcaaaa cgaagtccat ctcgagccat cagctggcga
    18721 aaatgttcca agtcaaaatc attggccact ttcttcttga gaccaaggtc ttcttgactg
    18781 cctagttctg ccaattctgg aaagacttga ttgagtgaga caggtatttc ttcaccatca
    18841 gcactttcaa ctttcaaatc ctccacagca gagtcgccaa tctttttctc taagagtctg
    18901 cgataaacag gatgctccaa gaagtcttga ctagatagag gagcatggag ggctagctga
    18961 taaacatccc ccttttgata gagggtcaag agattaaaag cagataagat tttcaatgat
    19021 tttatcagtc tatccatccc aaagttgaga tgattgagga tacttgaaaa aagatattcc
    19081 tttctaccat tatcccaaaa actgattgta taaagataaa ggctcagtgc ctcctgaccg
    19141 ataatcggga ggtagcactg taccagagat gaggtatctt gcgacacccg attattcttt
    19201 agataagaaa aacggtcaat tggcttcatt tatctttcct ttttcttttt agaggactgg
    19261 gtgatttgtt ggagcaagct ctctaactca ctgacatcct taaaactacg atagacacta
    19321 gcaaaacgta cataggtaat ctcgtccaat tcagccaact cctccatgac gagtgaacca
    19381 atgtcctcac tttgaatttc attttcattt cgaccacgga gtttctgttc gatacgattg
    19441 actaccatgt tgatttcatc acttgacaca ggacgtttct gggctgagcg gataatccca
    19501 ttaaagattt tatctctgga gaattgttcc cgtgtgccat cttttttaac aaccactaag
    19561 gttctttctt ctactcgttc gtaggttgta aaacggtgtt ggcactcgtc gcactctcgt
    19621 cttctacgaa tggtgttccc ttcttctgct tggcgactat cgataacact tgacttggta
    19681 gccccacatt ttggacaacg catcctttcc ctccttatcg ttttcttttc attataccat
    19741 tttttaagcg attcccaaaa caattcttct ttttgcttga caagtttttt gttttgttgt
    19801 attatttaat taagacaaaa ggataagaga aaggagacta agatgtcctg gacatttgac
    19861 aacaaaaaac ccatctattt acagattatg gagaaaatca agcttcagat tgtttcccat
    19921 acactggaac ccaatcaaca acttccaacc gtgagggagc tagctagcga ggctggtgtc
    19981 aatcccaata ccatccaaag agccttatca gaccttgaac gagaaggatt tgtctacagc
    20041 aagcgaacaa ctggacgatt tgtgactaag gataaggagc taatcgccca gtcacgcaaa
    20101 caattatcag aagaagaatt ggaacacttc gtttcctcca tgacccattt tggctatgaa
    20161 aaagaagaac taccaggcgt agtcagtgat tatattaaag gagtttaagc ctatgtcatt
    20221 actagtattt gaaaatgtat ccaaatcata tggagcaaca ccagcccttg aaaatgtttc
    20281 tcttgacatt ccagctggaa aaattgtcgg ccttcttggg ccaaacggct caggaaaaac
    20341 aaccctgatt aaactaatta atggcctctt acaaccagat caaggacgtg tcctcatcaa
    20401 cgacatggac ccaagcccag caaccaaggc cgttgtagct tatttgcctg atacgaccta
    20461 tctcaatgag caaatgaagg tcaaagaagc cctaacctac ttcaagacct tctataaaga
    20521 tttcaatctt gaacgcgccc atcatctact tgcagacctg ggcattgatg aaaatagtcg
    20581 tctcaagaaa ctatcaaaag gaaacaaaga aaaggttcaa ctgattttgg ttatgagccg
    20641 tgatgctcgt ctctatgttt tggacgaacc cattggtggg gtggatccag cagcccgtgc
    20701 ttatatcctc aataccatta tcaacaacta ctcaccaact tctaccgttt tgatttctac
    20761 ccacttgatt tctgatatcg agccaatctt ggatgaaatt gtcttcctaa aagacggaaa
    20821 agtcgtccgt caaggaaatg tagatgatat tcgctacgag tcaggtgaat ccattgacca
    20881 actcttccgt caggaattta aggcctaagc aaaggagatt atttatgttt tggaatttag
    20941 ttcgctacga atttaaaaat gttaacaagt ggtatttagc cctctacgca gccgtgctag
    21001 tcctttctgc cctcatcgga atacagacac aaggctttaa aaatctacct taccaagaaa
    21061 gtcaggctac tatgctactt tttctagcta cagtctttgg tggcttgatg cttacacttg
    21121 ggatttcaac cattttcttg attattaaac gcttcaaagg tagtgtctac gaccgacaag
    21181 gctatctgac tttgaccttg ccagtttctg aacaccatat catcacagcc aaactaatcg
    21241 gtgcctttat ctggtcattg attagcaccg ctgtattggc tctaagtgct gttattattc
    21301 tggctttaac agctccagaa tggattcctc tttcttatgt gattacattt gtagaaacac
    21361 atctccctca gatctttctt acaggtatat ccttcctact aaatactatt tcaggaatcc
    21421 tctgcatcta cctggctatt tccattggac agcttttcaa tgaataccgt acagcactcg
    21481 ctgttgcagt ctacattggt atccaaatcg tcattggatt tattgaactt ttcttcaatc
    21541 ttagttctaa tttctatgtc aattcactgg taggactcaa tgaccatttc tatatgggag
    21601 caggtatagc cattgttgaa gaactcatat tcatagctat cttttatctc ggaacctact
    21661 acatcttgag aaataaggtt aatttgcttt aaataatttt tacctagata tgtaacatac
    21721 tcatagaaca aaagagacca ggcaaaaagt ctttacaatt agaaaacgca tagtatcaag
    21781 tgttaaaaat ccttgatatt atgcgttttt tgtgagctga cttatttcct ttcactatat
    21841 cgcaaaatga aataagaacg gaacgatggg attttggaat tcaaatcaat ttataagaat
    21901 gttttagaag taatattatc ctattccaga ttcagttcac tatacaattg agttttcaag
    21961 caacctgttt acataatgtg tacataatta ggttcgtgat tccacccttt tcacctttaa
    22021 aaacctcgct ttcgcaaggc tcttctattt ataagataag gcacgtttaa aggttttcca
    22081 aatccctaaa tcatccgttt gaagaacgag actagcatac atgcgtccga taaatcctgt
    22141 tgctaccacc gcaaaaatca ctgtaatagc aagtgaaatc catgcttccg ctccctccgc
    22201 atagccatta atcgttcgaa acggcataaa gaaggtcgaa ataaagggaa tataagaacc
    22261 aatcttcaag aggagattgt caccagctgc acctagagct gtcactccaa aaaaaccacc
    22321 cataatcaaa atcatcaaag gcgacaaggc tttccctgag tcttcaggac gagaaaccat
    22381 agatcctagg aaggctgcca agactacgta catgaaaaga ctgatcaaaa taaagagcaa
    22441 ggtattcagt gagatagcat ctcccaagtg atccaaaata ccagactgag ccaagaatgg
    22501 caaatcttta aagagcaaaa cggcagccag accacctaca acatagatcc caatatgcgt
    22561 taaaatcact agaaacagag ccatcatccg cgcatagaaa tagtgacttg cccttatgct
    22621 agaaaagacg acttccataa ttttggtgcc tttttcactg gcaacttcct gagctgttac
    22681 acccgcatag gtaatcagaa tcatataaag aaagaatcct aaggcacctg ctgcaattgt
    22741 ttgaataaac tttttatttt ccttggcttc atcaatcttt tctgtgaatt gaattgtctg
    22801 cgctaagcgt ttttcctgct cttgagacaa ggaagcagtt gaacgattaa gctgattttg
    22861 cagttcattg agtgtacctg taacctcaaa tttaattcca ttttcaagcg atgtttcgcc
    22921 atgataaact gcctttagaa cactatcttc ttgatcaatg gtcaaataac cttttaattt
    22981 ttcttcttta attgcttctt tggcacttgc ttcgtcttta tagtcgaagt taacaccatt
    23041 tacattcttc agtccttctg ctacagatgg cactgttgtc actactgcca ctttattatt
    23101 tttagccata gaagaacctt ggagatgccc aattcctaca gagattccta aaaagaggaa
    23161 cggcgaaatc accataaaga agaaactcca tgactcgaca tgtcgaagat aggtttcctt
    23221 gattacaacc cacatatttc tcatacttcc actcctgatt ctagtttaaa gatttcatcg
    23281 atagttggcg cttgttggtc aaatgttgcg atatattgac cttgagtcaa gattgggaag
    23341 agttcccttc cagcgctctc atcctccaaa atcaatttcc aactgccttg tttggtcaag
    23401 ctcacctgtt tgacatgagg aagattttcc aattcttcct tgcttcgttc acttgaaaca
    23461 aagagacgcg ttttcccgta ttgattgcgg acatcctgaa ctggtccgtg caagaccaca
    23521 cggccatctc gaatcatcag aatatcgtca caaagttcct caacattggt catgacatgg
    23581 tcagaaaaga taatggttgc tccgcgctct ttttcctgaa aaatgacttg tttgagcaat
    23641 tctgtattaa ctgggtccaa tccactaaaa ggctcatcca agataatcag gtctggttca
    23701 tgaatcagag taataatgag ctgaatcttc tgctgatttc cttttgacag actcttgatt
    23761 ttatctgtca gctttccttt tacttccaac ctcttcatcc attgagggag tttttctttg
    23821 acttctttgg catccatgcc ttttagagtc gccaagtagc gaacttgttc aagaactgtc
    23881 aatttaggca tgagactgcg ttcttcaggc agataaccaa tccgagcata gatctcctga
    23941 cgaatatcct gaccatccag accgatttct ccctgatatt ctaggaattt taaaatacta
    24001 tggaaaatcg ttgtttttcc agcaccattt tttccgacta gtcccaaaat acgacctggt
    24061 cgcgcttgaa agtcaatacc aaacaaaact tgcttggatc caaaactttt ctctagactt
    24121 cttacttcta gcatctttca cctccgaaat ttcttgcact cattatactc ctttttgata
    24181 gcctttacaa tgttttttgt ccatttttag aagactattg ctgtgtaaaa tatggcctgg
    24241 agcactttta tactcaatga aaatcaaaga gcaaactagg aagctagccg tagactgctc
    24301 aaagtacagc tttgaggttg cagataaaac tgacgaagtc agctcaaaac actgttttga
    24361 ggttgtggat agaactgacg aagtcagtaa ctatacgtac ggcaaggcga agctgacgtg
    24421 gtttgaagag attttcgaag agtattagtg ataaatccat tatacagcag caaacttaat
    24481 ttataccttc cgctcctcaa ctgtctattt ttaatcctga attgttattt gagtaactcc
    24541 tttttcctcg taaagttttc ttcctctaaa acttctggaa aaaggctaat agtttcagac
    24601 aacattttta taagaaacaa gttcatctgt catttcaaga aggagtaatc ctttatctac
    24661 taatggacgg aacagaattc aaccgcttgt ccgatatgtt ttctaaggat tatatagtaa
    24721 aatgaaataa gaacaggaca aattgatcag gacagtcaaa ttgatttcta acaatgtttt
    24781 agaagtagat gtatactatt ctagtttcaa tctgctatat ctattatgca cacccctata
    24841 ggatctaatg aaaatcacaa caggctcatt catagatagt tacctcagga aactaagaaa
    24901 acgactacaa aggaagtcgc attcatcgaa aagtggatta acaactatcc taaaaaatgc
    24961 ttgaactaca agtcccccag agaagacttc tggatgacta acttgaactt gaaatttagc
    25021 aataattaat tcaccatcta actatattta gtaattattt cagaactgat taatattaaa
    25081 attaactaac aattcaaagg attcatacta gccataaatt acgtccatca gagagagact
    25141 cttactactt ttagatttta gtctttctag cttcagaata catctaaact ttagggaaaa
    25201 tgactattcg aaagcgcgaa tgcctcaaaa ttatctcaga taagctattc gaaacttaga
    25261 atgcttttaa atttatggaa ttgcgattat tcgaaaccta gaatgcatat aacctttagt
    25321 tgacagacct attctaagtc tcgaagggct atttactttc tattccttat caaaaaagac
    25381 tcattccccc tttctcctcc aaaatatggt atagtagaaa tatactatct atgaggagtt
    25441 tacatgtcac aggataaaca aatgaaagct gtttctcccc ttttgcagcg agttatcaat
    25501 atctcatcga ttgtcggtgg ggttgggagt ttgattttct gtatttgggc ttatcaggct
    25561 gggattttac aatccaagga aaccctctct gcctttatcc agcaggcagg catctggggt
    25621 ccacctctct ttatcttttt acagatttta cagactgtcg tccctatcat tccaggggcc
    25681 ttgacctcgg tggctggggt ctttatctac gggcacatca tcgggactat ctacaactat
    25741 atcggcatcg tgattggctg tgccattatc ttttatctag tgcgcctata cggagctgcc
    25801 tttgtccagt ctgtcgtcag caagcgcacc tacgacaagt acatcggctg gctagataag
    25861 ggcaatcgtt ttgaccgctt ctttattttt atgatgattt ggcccattag cccagctgac
    25921 tttctctgta tgctggctgc cctgaccaag atgagtttca agcgctacat gaccatcatc
    25981 attctgacca aaccctttac cctcgtggtt tatacctacg gtctgaccta tattattgac
    26041 tttttctggc aaatgctttg acacgtaaaa aatccgtttg gtttcccaag tggattttta
    26101 aagcgtagat taactatagc ttgatactaa atatactttg gtatggaaat catgcatatt
    26161 tttcgatagt gaagcgagga cttacctagc ctttccaccg tgatagaaac acctgaaatc
    26221 taatggtttc aggtgttcgg aaactttgag cctagtgtct caaagtttag gtatggaatt
    26281 tcgaagaaag tcgctaccgt ccgtaatcac ttaaggaaag gctcaaaaat attgttttca
    26341 accacaaaat ccgtttggtt tcccaagcgg attttgtgct ttattttgaa acttcttttg
    26401 caagaacaaa gttcccaagt gtggcagaac catttcctgc gactgctggc gtcacgatat
    26461 agtcacgcac atctggtact ggtaggtaac cattaagaag agatgtaaat ttctcacgga
    26521 cacggtccag catatgttgt tgagccatga cccctccacc aaagacaatc acgtctgggc
    26581 ggaaagtcac tgtcgcatta accgcagctt gagcgatata gtaggcttga acatcccaaa
    26641 cagggttgtt gagttcaata gtttccccac gtacacctgt acgagcttcc aaacttggac
    26701 cagctgcata gccttccaga catcccttat ggaaaggaca aacaccctta aactcttttt
    26761 caatatccat tgggtgtcta gcaacataat aatgacccat ttcagggtga cccacaccac
    26821 cgataaactc accacgttgg atgacgcctg caccgatacc tgtaccgatt gtgtagtaaa
    26881 ccaagttttc gatacgacca ccagcattgt tacgggcaac cacttcaccg taagcagagc
    26941 tgtttacgtc tgttgtgaag tacattggca cgtttagggc gcgacgaagg gcaccaagca
    27001 agtccacatt tgcccagttt ggttttggag tcgtcgtgat aaagccataa gtttttgagt
    27061 ttttgtcaat atcaatcggc ccaaatgaac caactgcaag accagcaagg ttatcgaatt
    27121 ttgagaagaa ctcaatggtt ttatcgattg tttcgattgg agttgttgtt ggaaattgtg
    27181 ttttttctac aacgttaaag ttttcatcac cgacagcaca gacaaacttt gtaccgccag
    27241 cttccaagct tccatataat tttgtcatga taaacctctt gtttttattt tctttattat
    27301 agcatacttc gaaagtctaa atgtctctat tttttagatt ttcctctgta aatcttacta
    27361 tctaataaaa acgaacaaac atgtcatttg ttcgttttca cattagagag gattgattag
    27421 attttcactt cgatcacagc atcccccttc gcaactgaac ctgttgcgac tggagctact
    27481 gaagcgtagt cagctgtatt tgtaacgata accattgttg tatcatcaag tccagctgta
    27541 gcgattttat ttgagtcaaa tgttccaaga acatcgccaa ctttcacctt atcaccttga
    27601 gcaacttttg cttcaaaacc gtcaccgttc atagatacag tgtcaatacc aacatgaatc
    27661 aaaacttcag caccatttct tgttttcaaa ccaaaagcgt gccctgttgg aaaggcaatt
    27721 gaaacttcag catcagctgg tgcatagacc acgccttggc ttggtttcac agcgatacct
    27781 tgtcccatag ctccacttga gaagactggg tcattgacat cagcaagagc gacaacatca
    27841 ccgacgatag gagttacaag tgtttcattt tgaagagctg ctggcgcaac ttcttctttt
    27901 tcttcagcca cttcagcttg ttttgcagct gcagttgcgt ctacttcatc ttcgtaacca
    27961 aacatgtaag taagagcaaa accaagggca aatgatacag ctaccataag aaggtattgt
    28021 ggaagttgtc cgttaccaac ataaagcatt gtaccaggga tgatggtgat accattacca
    28081 gtaccagcaa gtccaaggat agaagccaat ccaccaccga ttgcaccagc aatcaatgaa
    28141 aggaagaatg gtttacggaa gcgcaagttc accccgaaga tagcaggctc tgtaatacct
    28201 aggaaggcag aaagagcagc cgggaaagca agtgttttca gttttggatt ttttgtttta
    28261 acaccaaccg caacagtagc agcaccttga gctgtcatag cagctgtgat gatagcgttg
    28321 aatgggttag catggtcagc agcaagtaat tgcacttcaa gcaagttgaa gatgtggtgc
    28381 acacctgaca cgacgatcaa ttggtgaacc ccaccaatca agaaaccacc aagaccaaat
    28441 ggcatgctaa gaatcgcttt tgtagcaata aggatgtagt tttcaacaac gtggaaaact
    28501 ggtccaatga caaagagtcc aaggatagac atgaccaaaa gtgtcacgaa tggtgttacc
    28561 aagaggtcaa tgacatctgg aacaaccttg cggacagctt tttcaaattt agctccgaca
    28621 accccgatga tgaaggctgg aagaacggaa ccttgcaaac caacaacagg gatgaaacca
    28681 aagaagttca tcgctgttac ttcaccacct tgagcaactg cccaagcgtt tggaagtgag
    28741 ccagagacaa gcatcatacc aagaacgata ccaacggcag gatttccacc aaatacacgg
    28801 aaggttgacc acacaaccaa acctggcaag atgatgaagg ctgtatctgt caagatttgt
    28861 gtgtaagttg caaagtcacc tggaagtggc atttcaagag cgttgaaaag accacgcaca
    28921 cccatgaaga gacctgtcgc tacgataact gggatgattg gaacgaaaac atcaccaaaa
    28981 gtacggatag cacgttggaa ccagttccct tgtttagcaa cttctgcttt catgtcatcc
    29041 ttagatgatg ttggtaatcc aagtacaaca acttcatcgt acattttgtt aactgtacct
    29101 gtaccaaaga taatttggta ttgccctgag ttaaagaaag caccttgaac tttttccaag
    29161 ttctcaatca cttctttatt gattttctct tcatctttga ccatgacacg tagacgtgtc
    29221 gcacagtggg caacactatt gacattttca cgtccgccca aggcatcgat gacttttttt
    29281 gcaatttcct gattgttcat ttgcaaaaat ctccttatat aacattttgt tcttgtttga
    29341 aagcgatttt attcgccctt acgactatta ttttatcatg ttttaaaaat atgtcaagcg
    29401 ttttgcagaa aaaatattct atctacttag tgggcaagct ttagattgat tgtttttgac
    29461 tgtttcatca ggaatttctt gaaaaataag tttgaaacct tggttaaaaa gtcttttatt
    29521 tcattatctt tcacattttc gtaaaaattt gattgatttc ctgtatttat tttatgataa
    29581 tcgtttgaca gttttttctc ttttttaaca taaagggctt gcatttttta tcgaaaacag
    29641 ttactattaa aagtgataag atttttggag gaatgaatgg aatggacaac tgagcgtcgt
    29701 tacagacttt atcaagattg gacgcaagaa gaaattcaac atataaagga aaatatggca
    29761 caatctccat ggcatactca ttaccatgtt gagccaaaaa caggacttct caacgaccca
    29821 aatggctttt cttactttga tggcaagtgg atcctctttt accagaattt tccttttggt
    29881 gcagcccacg gtttaaaatc ttgggcacag ctagaaagtg atgatttggt tcactttaga
    29941 gaaactggag tcaaagtttt gccagatact ccattagata gtcacggtgc ctactctggt
    30001 tctgccatgc aatttggcga taacttattc ctattttata caggaaatgt tcgcgatgaa
    30061 aactggatcc gtcacccata ccagatcggt gctttgatgg acaaggaggg taagattaca
    30121 aagattgaca agatcttgat tgaccagcca gcagactcta ctgaccactt ccgcgatcca
    30181 caaattttta actttaaagg tcaatactat gctgtcgtcg gtggacagga cttggagaaa
    30241 aaaggcttcg tccgtctcta caaggctgtc aataacgact acacaaactg gcaagcagtt
    30301 ggcgaccttg actttgctaa cgaccgtact gcctacatga tggaatgtcc taatctggtc
    30361 tttgtagagg aacagcctgt ccttctctac tgtccacaag gattggataa gaaagttcta
    30421 gactacgata atatctttcc aaatatgtat aagattgggg cttcctttga ccctaaaaat
    30481 gccaaaatgg tagatgtgtc tcaacttcaa aacatggatt acggtttcga agcctatgca
    30541 actcaagcct tcaacgctcc tgatgggcgt gctctagcag ttagctggct tggtttgcca
    30601 gatgtttctt acccatctga ccgttttgac caccaaggaa ccttctcttt ggtcaaggaa
    30661 ctcactatca aagacgacaa gctctaccag tatccagtcg ctgctattaa ggaccttcgt
    30721 acttctgaag aagccttctc aaaccgttcc caaaccaaga acacttacga acttgaactc
    30781 aacttggaag ctaatagcca gagcgagatt gtcttacttg ctgataaaga aggtaaggga
    30841 ctttcaatca actttgacct tgtaaacggt caagtgacag tggatcgtag ccaggctgga
    30901 gagcagtatg cccaagaatt tgggataact cgttcttgcc ctatcgagaa tcaggctact
    30961 actgctacaa tcttcatcga taactctgtc tttgaaattt tcatcaataa aggagaaaaa
    31021 gtattttctg gtcgtgtctt cccacatgcg gaccaaaatg gtatcctgat caaatctgga
    31081 aacccaactg gaacttacta tgaattagat tatggtcgca aaactaactg atgtcgccaa
    31141 acttgcaggc gtcagtccta ctaccgtttc tcgggttatc aataaaaaag gatatctatc
    31201 tgagaaaacc atccaaaaag tcaatgaagc catgcgagaa ttgggctata aacccaacaa
    31261 cctggctcgt agtctgcaag gaaaaccagc taagttaatc ggcttgattt tccccaatat
    31321 ttccaatgtt ttctatgcag aattgattga taaattggaa caccaactct tcaaaaatgg
    31381 ttacaagacc atcatctgca acagtgaaca tgattctgag aaggaacgtg aatacatcga
    31441 aatgttggaa gccaatcagg tggacggcat catttctggt agtcacaacc taggaatcga
    31501 agactacaat cgtgtgacag cgccgattat ttcctttgac cgaaacctat cgccagacat
    31561 ccctgtcgtc tcctctgaca actatgctgg tggggttctt gctgcccaaa ccttggtcaa
    31621 gacaggtgcc cagtctatca tcatgattac agggaatgac aattccaatt cgccaaccgg
    31681 actgcgccac gctggttttg catccgtact cccaaaagct cctattatca atgtttccag
    31741 tgacttttct cccgtcagaa aagaaatgga aatcaagaat atcttgaccc gggaaaaacc
    31801 agatgccatt tttgcttcgg atgatttgac agctattctg gtcattaaaa tcgctcaaga
    31861 attgggcatt tctgtcccaa aagagctcaa ggtcatcggc tatgatggga cctactttat
    31921 cgaaaattac taccctcaat tggctactat caagcaacct ttggaagaga ttgcttgtct
    31981 cactattgat cttctcttgc aaaagattga aggcaaggaa gtcgccacaa ctggttactt
    32041 cttaccagtt acgctattac caggaaaaag tatttaaaca caagaaaact cagaccgatt
    32101 cgtctgagtt tttatgatct taaattttcg agatagcgct gggctgtctc taggttaaag
    32161 gttttatctg agatgaggcg ctctactagg ggagcaactt cagattcact agccccagct
    32221 aggagagcta gggatttggc ctgtagtttc atgtggcctt gctggatgcc cgtacttacc
    32281 aaggctttga gggctgcaaa attttgagca agaccgatgg acacgataat ctgggctaat
    32341 tctctggcag aaggatttcc tagtagatca tgactgagag ctacacgtgg gttgaggccg
    32401 atagagccac ccttagtcgc tacaggcatg ggcagggtca tctcaccgac caattcttct
    32461 ctttcaaggt ccagcgtcca gcagctaaga ccttgatagc gtccatctcg actggcaaag
    32521 gcatgggccc cagcttcgat ggcacgccag tcattaccag tggcaatcaa aatcgcatca
    32581 ataccattaa aaattccttt attatgagta gcagctcggt aaggatcagc ctgcgcaaac
    32641 tgactagcca acgcaatttt ctccgcaatc tctcgtcctt gatccttttg gcggctcaag
    32701 tagcgaaagg cgatgcgaca gcttgcagtc accagagaat cagtcgcgta gttggacagg
    32761 attcccatga gactctgtcc ctgactgagt tcttctaaga ctggtttcaa ggcttccagc
    32821 atggtgttga gcatattggc acccatggct tcctgggtat cgacatgaat ataaacaacg
    32881 agaaagtctg gttcgccttt tatctgctcg acatgcagat cacgcgcccc acccccacgt
    32941 ttaacgatag aaggataggc ttgattggca agctccaaga gctccgcttt cttgctggca
    33001 atcttctctt gcgctagttt aggattagca acttgataaa gggctacctg cccaatcatc
    33061 tggcgctgat ggacttgtgc agtaaaacca cctgcacgct tgatgatttt gctggcatag
    33121 ctggccgccg caaccacaga gggttcttct gtcacatagg gaacggtgta ttcctgaccg
    33181 ttgacaagta cctccggaac cagcgaataa ggcagagaaa aagttcccac cacattctca
    33241 ctcagctggt ctgccacagt cacactcatc tgttcatcct tctccagact agcttgtctc
    33301 tcaggactaa ggagcgcctg agcttttagc agctcgaggc gctcttggta tgatttttta
    33361 gaaaatccat tccaacttat cttcattatt tttcaacctt gctataacgg cgttggtggt
    33421 caagaatttc aaccaaggca aaatcttgat tttcatagcc agcaaactgg gcagagtttg
    33481 tttcatccaa gtttacttcc tcaaaaaaga ccttttcata gtctgcaacg gatagggcag
    33541 ttcgttggtt gagcttgttc aagcggtctt tatccaaata agcttcatat ccttcaacca
    33601 attcaccact gaagaactca gccacagctc cacttccgta actataaagg gcgattttat
    33661 ccccagcttt caagctatct gtattttcca agagagacaa aagtccaagg aaaagtgaac
    33721 ctgtgtagat attccccacc ttttgactgt agagaataga ctggtcaaaa tgcttttgta
    33781 agaggtcttt tttctcttga ggcaggctct tatccatgat ttttttcaag ccttttagcg
    33841 ctaatttagg ataaggcaag tggaaacaaa cagccgcaaa atcatccaaa gtaagctggt
    33901 agcgtttttg atattcaagc caagtcgttt tcaaactatc caagtattgt tgggtagaat
    33961 agacaccatt tacataagga gttgtcgagt aatttggtcg ccagaaatcc atgatgtcac
    34021 gggtctgagc tacattgtca ttattaaagg ccatcatgcg tggattttgt gtaatcaaca
    34081 tagctacact tccagcacct tgagttggtt ctcccggagt ttcaatacca tatttggcaa
    34141 tatcactggc aatgaccaag accttggact ccggagaatt ttccacatgc aatttggcat
    34201 aatggagggc agctgtcgcc ccatagcagg cttctttaat ctcgaaacta cgagcaaagg
    34261 gctggatgcc cagcaagcca tgcacaaaga cggccgcagc cttactctgg tcaattcctg
    34321 actcggtagc cacaatgacc atgtcaactt cttgtctttc ttgctcagtt aaaatagagt
    34381 cactagcact ggccgccaag gtcacgatgt cctcagttag gggcgcaata ctcaattcct
    34441 tgagtaagag tcctttactt aatttttcag ggtcaattcc cctcgcttct gctaagtctt
    34501 gtaatttcaa gacatattga ctggtcgcaa aaccaatctt atcaataccg attgtcatat
    34561 ttacctctgt tttatcattc atgtaaaaaa tcgttctata ctattttatc acaaatggca
    34621 gtaaaagaga gaaaaaagac ttgattcacc aaatcaagcc tcttattggt catcatttta
    34681 aagaatgatt agttgctaga gagttcaccg atataagtag ctttataagc tccattcaca
    34741 gttatcagct cctggaggat caaatttcct gagtaaatcc ttcccatctc atctacaaat
    34801 ttttgataaa actgactgat cggaatttct ctgacatcct tatcaaatgt cttatcaagt
    34861 gttttactaa ccttctcagc aatcaattga tgctcttgcc atccactttg aaactctgag
    34921 cccgaactag aaaccatgac tgggataaac aacaaggtca gtagatttac agacaataag
    34981 gaaagtagta gacttc
//
LOCUS       DBEJJV010000023        34520 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.023, whole genome shotgun sequence.
ACCESSION   DBEJJV010000023 DBEJJV010000000
VERSION     DBEJJV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.023"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            677..1129
                     /locus_tag="ACL3GT_001238"
     CDS             677..1129
                     /locus_tag="ACL3GT_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0516907.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKAGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1148..2485
                     /locus_tag="ACL3GT_001239"
     CDS             1148..2485
                     /locus_tag="ACL3GT_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0516908.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2564..3448
                     /locus_tag="ACL3GT_001240"
     CDS             2564..3448
                     /locus_tag="ACL3GT_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0516909.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWIINGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3448..4281
                     /locus_tag="ACL3GT_001241"
     CDS             3448..4281
                     /locus_tag="ACL3GT_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0516910.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4299..6392
                     /gene="nanB"
                     /locus_tag="ACL3GT_001242"
     CDS             4299..6392
                     /gene="nanB"
                     /locus_tag="ACL3GT_001242"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HGR0516911.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6404..7507
                     /locus_tag="ACL3GT_001243"
     CDS             6404..7507
                     /locus_tag="ACL3GT_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0516912.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7681..8379
                     /locus_tag="ACL3GT_001244"
     CDS             7681..8379
                     /locus_tag="ACL3GT_001244"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR0516913.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8398..9915
                     /locus_tag="ACL3GT_001245"
     CDS             8398..9915
                     /locus_tag="ACL3GT_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HGR0516914.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALAVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETIAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            10040..11368
                     /locus_tag="ACL3GT_001246"
     CDS             10040..11368
                     /locus_tag="ACL3GT_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0516915.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11620..12486
                     /locus_tag="ACL3GT_001247"
     CDS             11620..12486
                     /locus_tag="ACL3GT_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0516916.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAIMIAIVSF
                     VQFKVLGNDVEY"
     gene            12502..13341
                     /locus_tag="ACL3GT_001248"
     CDS             12502..13341
                     /locus_tag="ACL3GT_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HGR0516917.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13613..14065
                     /locus_tag="ACL3GT_001249"
     CDS             13613..14065
                     /locus_tag="ACL3GT_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0516918.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNRFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14162..14506
                     /locus_tag="ACL3GT_001250"
     CDS             14162..14506
                     /locus_tag="ACL3GT_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516919.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVTALIGRYIKLGTY
                     AVKYGISMARSILSRAAATAAARVGLLTKIFGWILRIAVLAADVYGNFANNIAVAWDA
                     HDKIPNNGRINF"
     gene            14516..14710
                     /locus_tag="ACL3GT_001251"
     CDS             14516..14710
                     /locus_tag="ACL3GT_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516920.1"
                     /translation="MKALCIFLLYMLAWTVLAMIIRGGLDGFDEHTWRTILIASLSGI
                     YIDYMSIDKSRKKSKRKKKK"
     gene            14793..15437
                     /locus_tag="ACL3GT_001252"
     CDS             14793..15437
                     /locus_tag="ACL3GT_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HGR0516921.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEVLQKGLILASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15606..16523
                     /locus_tag="ACL3GT_001253"
     CDS             15606..16523
                     /locus_tag="ACL3GT_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HGR0516922.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTSSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTAAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEDDRPVVEAAAALIRETKERFL"
     gene            16541..17425
                     /locus_tag="ACL3GT_001254"
     CDS             16541..17425
                     /locus_tag="ACL3GT_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0516923.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17441..18292)
                     /locus_tag="ACL3GT_001255"
     CDS             complement(17441..18292)
                     /locus_tag="ACL3GT_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGR0516924.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKNSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18492..20549
                     /gene="pbp2b"
                     /locus_tag="ACL3GT_001256"
     CDS             18492..20549
                     /gene="pbp2b"
                     /locus_tag="ACL3GT_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HGR0516925.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20560..21156
                     /gene="recR"
                     /locus_tag="ACL3GT_001257"
     CDS             20560..21156
                     /gene="recR"
                     /locus_tag="ACL3GT_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HGR0516926.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDSTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21332..22375
                     /locus_tag="ACL3GT_001258"
     CDS             21332..22375
                     /locus_tag="ACL3GT_001258"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HGR0516927.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDSIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWENMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22459..23832
                     /gene="murF"
                     /locus_tag="ACL3GT_001259"
     CDS             22459..23832
                     /gene="murF"
                     /locus_tag="ACL3GT_001259"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HGR0516928.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     SLENECK"
     gene            23819..24430
                     /locus_tag="ACL3GT_001260"
     CDS             23819..24430
                     /locus_tag="ACL3GT_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase N-terminal domain-containing
                     protein"
                     /protein_id="HGR0516929.1"
                     /translation="MNASDFAKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDADEVAELLKPTSAYATPLMDVRAWIVEDEKICLVRGQGENDWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24521..25225
                     /locus_tag="ACL3GT_001261"
     CDS             24521..25225
                     /locus_tag="ACL3GT_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HGR0516930.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYRENK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25444..26817
                     /gene="ftsA"
                     /locus_tag="ACL3GT_001262"
     CDS             25444..26817
                     /gene="ftsA"
                     /locus_tag="ACL3GT_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HGR0516931.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26834..28093
                     /gene="ftsZ"
                     /locus_tag="ACL3GT_001263"
     CDS             26834..28093
                     /gene="ftsZ"
                     /locus_tag="ACL3GT_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HGR0516932.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28098..28769
                     /locus_tag="ACL3GT_001264"
     CDS             28098..28769
                     /locus_tag="ACL3GT_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HGR0516933.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28779..29318
                     /locus_tag="ACL3GT_001265"
     CDS             28779..29318
                     /locus_tag="ACL3GT_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HGR0516934.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29318..29581
                     /locus_tag="ACL3GT_001266"
     CDS             29318..29581
                     /locus_tag="ACL3GT_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HGR0516935.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29578..30363
                     /locus_tag="ACL3GT_001267"
     CDS             29578..30363
                     /locus_tag="ACL3GT_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HGR0516936.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30372..31160
                     /gene="divIVA"
                     /locus_tag="ACL3GT_001268"
     CDS             30372..31160
                     /gene="divIVA"
                     /locus_tag="ACL3GT_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HGR0516937.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31508..34300
                     /gene="ileS"
                     /locus_tag="ACL3GT_001269"
     CDS             31508..34300
                     /gene="ileS"
                     /locus_tag="ACL3GT_001269"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HGR0516938.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10642 a         6082 c         7499 g        10297 t
ORIGIN      
        1 atttttgaaa gtacttttaa tatacttgat atagttaaaa aagatttgaa actaaattcc
       61 aaattagaaa aagacttgaa atactaaaaa aaaaagcata ctctaattga aaacggtaac
      121 aaaactaatt tagagaatga aatatagagt atttctctct taaaagtttt tggtgaaacg
      181 agatgtagaa aggagattta gccaaagagt ctattagtgc tagaataata gattagaatt
      241 attttagaaa aacgaagtga gcagcttata aattcaagtc cccaaataga ttcatactag
      301 tatcttttgc aaaaaataaa gggcgacttc cttcatgaat atcaatttca tctataagga
      361 aggtagctaa ttgaactaac ttatttattc tgtttgtcgc tagaaaaatc agacctcctt
      421 gtgaagattg aggagatact taatgaaaat caaagaagaa actagcaagc tagtagcaga
      481 ttgcccaaaa caccgctttg aggttgtaga taagactgac gtatataatc caaggtgaag
      541 cgactgtggt ttgaagagat tttcaaagag tataggctag agagtagtgt ttttatgtcc
      601 ttctagtaga aaatgctaga cagaagaatg gggaacttgg ataggagaaa tagattgaga
      661 aaggaggtta gaagagatga ttattacaaa aattagccgt ttaggaactt atgtgggagt
      721 aaatccacat tttgcaacat taatagattt tctagaaaaa gcaggactag aaaatttaac
      781 agaaggttcg attgctatcg atggtaatcg attgtttggg aattgcttta cttatctagc
      841 agatggtcaa gcaggggctt tctttgaaac acaccaaaaa tatttggata ttcatttagt
      901 tttggaaaac gaagaagcca tggctgttac atcgccggaa aatgtaagcg ttacccaaga
      961 atatgatgaa gagaaagata ttgaattata cacagggaaa gtggaacagt tggttcagtt
     1021 gagagctggc gaatgcctca tcacttttcc agaagattta catcaaccca aggttcgtat
     1081 aaatgatgaa cctgtgaaaa aagttgtctt taaagttgcg atttcttaat gtagaaagag
     1141 aagaacgatg aaaaaaatga gaaagttttt atgtctagct ggaattgcgc tagcggctgt
     1201 tgccttggta gcttgttcag gaaaaaaaga agctacaact agtactgaac caccaacaga
     1261 attatctggt gagattacaa tgtggcactc ctttactcaa ggaccccgtt tagaaagtat
     1321 tcaaaaatca gcagatgctt tcatgcaaaa gcatccaaaa acgaaaatca agattgaaac
     1381 attttcttgg aatgacttct atactaaatg gactacaggt ttagcaaatg gaaatgtgcc
     1441 agatatcagt acagctcttc ctaaccaagt aatggaaatg gtcaactcag atgctttggt
     1501 tccgctaaat gattctatca agcgtattgg acaagataaa tttaacgaaa ctgccttaaa
     1561 tgaagcaaaa atcggagatg attactactc tgttcctctt tattcacatg cacaagtcat
     1621 gtgggttaga acagatttgt taaaagaaca taatattgag gttcctaaaa cttgggatca
     1681 actctatgaa gcttctaaaa aattgaaaga agctggagtt tatggcttgt ctgttccgtt
     1741 tggaacaaat gacttaatgg caacacgttt cttgaacttc tacgtacgta gtggtggagg
     1801 aagcctctta acaaaagatc ttaaagcaga cttgacaagc caacttgctc aagatggtat
     1861 taaatactgg gttaaattgt ataaagaaat ctcacctcaa gattctttga actttaatgt
     1921 ccttcaacaa gctaccttgt tctatcaagg aaaaacagca tttgacttta actctggctt
     1981 ccatatcgga ggaattaatg ccaacagtcc tcaattgatt gattcgattg atgcttatcc
     2041 tattccaaaa atcaaagagt ctgataaaga ccaaggaatt gaaacctcaa acattccaat
     2101 ggttgtttgg aaaaattcaa aacatccaga agttgctaaa gcattcttag aagcacttta
     2161 taatgaagaa gactacgtta aattccttga ttcaactcca gtaggtatgt tgccaactat
     2221 taaggggatt agcgattctg cagcctataa agaaaatgaa actcgtaaga aatttaaaca
     2281 tgctgaagaa gtaattactg aagctgttaa aaaaggtact gctattggtt atgaaaatgg
     2341 accaagtgta caagctggta tgttgactaa ccaacacatt attgaacaaa tgttccaaga
     2401 tatcattaca aatggaacag atcctatgaa agcagcaaaa gaagcagaaa aacaattaaa
     2461 cgatttattt gaggctgttc agtagatgta aaagactaga aaataggtgg gctagtgagc
     2521 tgaaaagctc tagcccaatc ttgtaaaaga agggagaagg agaatggtta aagaacgtaa
     2581 tttaactcgc tggatatttg ttttgccagc tatgattatc gtaggattac tctttgttta
     2641 tccgtttttc tcgagtattt tttatagctt taccaataag catttgatta tgcctaatta
     2701 taaatttgtt ggtttggcta actataaagc tgtgctatca gatcccaact tctttaatgc
     2761 gttctttaat tcaattaagt ggaccgtttt ctcattagtt ggtcaagttt tagtagggtt
     2821 tgtattggct ttagctcttc acagagtacg ccacttcaag aaattatata ggaccttatt
     2881 gattgttcct tgggcatttc ctaccatcgt tattgccttc tcttggcagt ggattataaa
     2941 cggggtttat ggctacttac ctaatctaat cgtaaaatta ggtttaatgg aacatacacc
     3001 tgcatttttg acagatagta catgggcatt cctatgtttg gtgtttatca acatttggtt
     3061 tggagcacca atgattatgg ttaatgtgct ttcagctttg caaacagtac cagaagaaca
     3121 atttgaggct gctaagatag atggtgcttc aagttggcag gtgttcaagt ttatcgtctt
     3181 tccacatatt aaagtggttg taggacttct agttgttttg agaactgtat ggatctttaa
     3241 taactttgac attatctacc tcattactgg tggtggacca gccaatgcta caacgacgct
     3301 tccaattttt gcttacaacc tgggttgggg aactaaattg ttgggtcgtg cttcagcagt
     3361 tacagtattg ctctttatct tcttggtggc gatttgcttt atctactttg ctatcatcag
     3421 taagtgggaa aaggagggta gaaaataatg aagaagaaat ccagtattta tttagatatt
     3481 ctctcacatg tacttttagt tggtgcgacc atcgttgcaa ttttcccatt ggtatggatt
     3541 atcatatctt ctgtcaaagg gaaaggggaa ttaactcagt atccaacacg attttggcct
     3601 gaacagttta cattagatta tttcactcat gttatcaacg atttgcactt cattgataac
     3661 attcgaaaca gtttaatcat tgccttggct acaaccctca ttgcgattat tatttctgct
     3721 atggcagcct atggtattgt tcgattcttt cctaaattgg gagcaatcat gtcgagacta
     3781 ctcgtcatta cctacatttt cccaccaatt ttgttagcaa ttccctattc aattgccatt
     3841 gctaaagttg ggttaacaaa tagtttattt ggcttgatga tggtttatct atcttttagt
     3901 gttccatatg cagtttggct cttagttgga tttttccaaa cagttccaat tggaattgaa
     3961 gaagcggcta gaattgatgg tgcaaataaa tttgttacgt tttataaagt tgtgctaccg
     4021 attgtagcac caggtattgt agcaacagct atttatacat ttatcaatgc ttggaatgaa
     4081 ttcctgtatg ccttgatttt gattaacaat acaggaaaga tgacagtagc agtagccctt
     4141 cgttcactta atggttcaga aatactagac tggggagata tgatggcagc gtctgttatt
     4201 gtagttcttc catcaattat tttcttctct atcatccaaa ataagattgc aagtggatta
     4261 tcagaaggat ctgtgaagta gacgaaagaa ggaaaaaaat gaataaaaga ggtctttatt
     4321 caaaactagg aatttctgtt gtaggcatta gtcttttaat gggagtcccc actttgattc
     4381 atgcgaatga attaaactat ggtcaactgt ccatatctcc tatttttcaa ggaggctcat
     4441 atcaactgaa caataagagt atagatatca gccctttgtt attagataaa ttgtctggag
     4501 agagtcagac agtagtaatg aaatttaaag cagatgaacc aaactctctt caagctttgt
     4561 ttggcctatc taatagtaaa gcaggcttta aaaataatta cttttcaatt ttcatgagag
     4621 attctggtga gataggtgta gaaataagag acgcccaaaa gggaataaat tatttatttt
     4681 ccagaccagc ttcattatgg ggaaaacata aaggacaggc agttgaaaat acactagtat
     4741 ttgtatctga ttctaaagat aaaacataca caatgtatgt taatggaata gaagtgttct
     4801 ctgaaacagt tgatacattt ttgccaattt caaatataaa tggtatagat aaggcaacac
     4861 taggagctgt taatcgtgaa ggtaaggaac attacctcgc aaaaggaagt attggtgaaa
     4921 tcagtctatt taacaaagca attagtgatc aggaagtttc aactattccc ttatcaaatc
     4981 catttcagtt aattttccaa tcaggagatt ctactcaagc taactatttt agaataccga
     5041 cactatatac attaagtagt ggaagagttc tatcaagtat tgatgcacgt tatggtggga
     5101 ctcatgattc taaaagtaag attaatattg ccacttctta tagtgatgat aatgggaaaa
     5161 cgtggagtga gccaattttt gctatgaagt ttaatgacta tgaggagcag ttagtttact
     5221 ggccacgaga taataaatta aagaatagtc aaattagtgg aagtgcttca ttcatagatt
     5281 catccattgt tgaagataaa aaatctggga aaacgatatt actagctgat gttatgcctg
     5341 cgggtattgg aaataataat gcaaataaag ccgactcagg ttttaaagaa ataaatggtc
     5401 attattattt aaaactaaag aagaatggag ataacgattt ccgttataca gttagagaaa
     5461 atggtgtcgt ttatgatgaa acaactaata aacctacaaa ttatactata aatgataagt
     5521 atgaagtttt ggagggagga aagtctttaa cagtcgaaca atattcggtt gattttgata
     5581 gtggctcttt aagagaaaaa cataatggaa aacaggtccc tatgaatgtt ttctacaaag
     5641 attcgttatt taaagtgact cctactaatt atatagcaat gacaactagt cagaatagag
     5701 gagagagttg ggaacaattt aagttgttgc ctccgttctt aggagaaaaa cataatggaa
     5761 cttacttatg tcccggacaa ggtttagcat taaaatcaag taacagattg atttttgcaa
     5821 catatactag tggagaacta acctatctca tttctgatga tagtggtcaa acatggaaga
     5881 aatcctcagc ttcaattccg tttaaaaatg caacagcaga agcacaaatg gttgaactga
     5941 gagatggtgt gattagaaca ttctttagaa ccactacagg taagatagct tatatgacta
     6001 gtagagattc tggagaaaca tggtcggaag tttcgtatat tgatggaatc caacaaactt
     6061 catatggcac acaagtatct gcaattaaat actctcaatt aattgatgga aaagaagcag
     6121 tcattttgag tacaccaaat tctagaagtg gccgtaaggg aggtcaatta gttgtcggtt
     6181 tagtcaataa agaagatgat agtattgatt ggaaatacca ctatgatatt gatttgcctt
     6241 cgtatggtta tgcctattct gcgattacag aattgccaaa tcatcacata ggtgtactgt
     6301 ttgaaaaata tgattcgtgg tcgagaaatg aattgcattt aagcaatgta gttcagtata
     6361 tagatttgga aattaatgat ttaacaaaat aaaggagaaa aacatggtta aatacggtgt
     6421 tgttggagca gggtattttg gagctgaatt ggctcgctac atgcaaaaga atgatggagc
     6481 agagattact cttctctatg atccagataa tgcagaggcg attgcagaag aattgggagc
     6541 aaaagtagca agttccttag atgagttggt ttctagcgat gaagtagatt gtgttatcgt
     6601 cgcaactcca aataatcttc ataaggaacc ggttattaag gctgcacagc atggtaaaaa
     6661 tgttttctgt gaaaaaccaa ttgcgctttc ttatcaagat tgtcgcgaga tggtagatgc
     6721 gtgtaaagaa aacaatgtaa cctttatggc aggacatatt atgaatttct ttaatggtgt
     6781 tcatcatgca aaagaactca ttaatcaagg agttatcgga gacgttctat attgtcatac
     6841 agctcgtaat ggttgggaag aacaacaacc gtcagtatca tggaaaaaaa ttcgtgaaaa
     6901 atcaggtggt cacttgtatc accacatcca tgaattggat tgcgttcaat tccttatggg
     6961 gggcatgcct gaaactgtaa ccatgacagg tggaaatgtg gcccatgaag gtgaacattt
     7021 cggtgatgaa gatgatatga tttttgtcaa tatggaattt tctaataagc gttttgcttt
     7081 gttagaatgg ggttcagctt atcgttgggg tgaacattat gtcttaatcc aaggaagcaa
     7141 aggtgccatc cgcttagact tattcaactg taaaggaact cttaagctag atgggcaaga
     7201 aagctatttc ttgattcacg aatcgcaaga agaagatgat gatcggactc gtatctatca
     7261 tagtacagag atggatggag caattgctta tggtaaacca ggtaaacgta ctccattatg
     7321 gctatcatct gtcattgata aagaaatgcg ctatctgcat gagattatgg aaggagctcc
     7381 agtatcagaa gaatttgcaa aacttttgac aggtgaagct gccctagaag caattgctac
     7441 tgcagatgct tgtacccagt ctatgtttga agatcgcaaa gtaaaattgt cagaaattgt
     7501 aaaataaatt ttggtattct cctatttata ggtcgacttg ctcctctgaa agtactttta
     7561 gaggagctgt ttgactttgc tagtttttga aactgaaatc tattatacta caaactattg
     7621 aaagcgtttt aattttaagg tataataatc tcatagaaat aaagaaaagg aggaaagagg
     7681 atgccacaga ttagcaaaga agccttgatt gagcaaatca aagatggaat catcgtttct
     7741 tgtcaggctc ttcctcatga accgctttat acagaagcgg gaggggtgat tcccttgctg
     7801 gtcaaagcgg ctgagcaagg tggagcagtc ggtatccgag caaacagtgt tcgcgatatc
     7861 aaggaaatta aggaggtcac taaacttcca atcattggga ttatcaaacg tgattatcca
     7921 cctcaggaac ccttcatcac ggctactatg aaagaagttg atgaattggc agaactggac
     7981 atcgaggtga ttgctctgga ttgtaccaag cgtgaacgct acgatggttt ggaaattcaa
     8041 gagttcattc gtcaggttaa ggagaaatat cctaatcagc ttttgatggc tgatactagt
     8101 atcttcgaag aagggctagc agctgtagaa gcaggaattg actttgtcgg aacaacctta
     8161 tcaggctaca catcctacag tccaaaagta gacggtccag attttgaatt gattaagaaa
     8221 ctctgtgatg ccggtgtaga tgtcattgca gaaggaaaaa ttcatacacc agaacaagcc
     8281 aaacaaatcc ttgaatatgg agtgcgaggc atcgttgttg gtggcgccat tactagacca
     8341 aaagagatta cagaacgctt cgttgctagt cttaaataag atgtgagggg gagttttatg
     8401 tttaaagttt tacaaaaagt tggaaaagct tttatgttac ctatagctat acttcctgca
     8461 gcaggtctac ttttggggat tggtggtgca ctttcaaacc caaccacgat agcaacttat
     8521 ccaatactag acaatagtat ttttcaatca atattccaag taatgagctc tgcaggagag
     8581 gttgtattca gtaatttgtc actacttctc tgtgtgggat tatgtattgg cttagcgaaa
     8641 cgagataaag gaaccgctgc gttagcagga gtaactggtt acttagttat gactgcaacg
     8701 atcaaagctt tggtaaaact ttttatggca gaaggatctg caattgatac tggagttatt
     8761 ggagcattag ctgtcggaat agttgccgta tatttgcaca accgatataa caatattcaa
     8821 ttaccttccg ctttaggatt ctttggaggt tcacgcttcg ttcctattgt tacatcgttc
     8881 tcttctatct tgattggctt tgtcttcttt gttatttggc cacctttcca acaacttctt
     8941 gtttctacag gtggatatat ttctcaggcg ggtccaattg gaacttttct atatggattt
     9001 ttaatgagac tttctggagc agtaggctta catcatataa tttaccctat gttttggtat
     9061 actgaacttg gtggtgttga aactattgca ggacaaacag tggttggagc tcaaaaaata
     9121 ttttttgctc aattagccga tccggcccat tctggattat ttacagaagg aacaaggttt
     9181 tttgcaggtc gtttctcaac aatgatgttc ggtttaccgg ctgcctgttt agcgatgtac
     9241 catagtgttc ctaaaaatcg tcgtaaaaaa tacgcgggtt tgttttttgg agttgcttta
     9301 acatctttta ttaccggtat tacagaacca attgaattta tgtttctatt cgtcagtccg
     9361 gttctatatg ttgttcacgc attccttgat ggtgttagct tctttattgc agacgtctta
     9421 aatatttcaa taggaaacac attttcagga ggtgtaatcg atttcacttt atttggaatt
     9481 ttgcagggga acgctaagac gaattgggtt cttcagattc caattggact tatttggagt
     9541 gttttgtatt atattatttt tagatggttc attactcaat tcaatgttct aacgccagga
     9601 cgaggagaag aagtagattc taaagaaatt tctgaatccg cagattcaac ttcaaatact
     9661 gcagattatt taaaacagga tagcctacaa attatcagag ccttgggtgg atcaaataat
     9721 atagaagatg tagatgcttg tgtgacacgt ttacgtgtag ctgtaaaaga agttaatcaa
     9781 gttgataaag cacttttaaa acaaattggt gcagttgatg tcttagaagt gaagggtggc
     9841 attcaagcaa tctatggagc aaaagcaatc ttatataaaa atagtattaa tgaaatttta
     9901 ggtgtagatg attaagtact tactgactta ataaaaaaca gaggagagtg atggatgagt
     9961 aggatgaaat gaaatcgcat acaagaaata aagaactcat tatccaagtt ggatacgctt
    10021 attacatagg agaatacaaa tgaaatttag aaaattagct tgtacagtac ttgcgggtgc
    10081 tgcggttctt ggtcttgctg cttgtggcaa ttctggcgga agtaaagatg ctgccaaatc
    10141 aggtggtgac ggtgccaaaa cagaaatcac ttggtgggca ttcccagtat ttacccaaga
    10201 aaaaactggt gacggtgttg gaacttatga aaaatcaatc atcgaagcgt ttgaaaaagc
    10261 aaacccagat ataaaagtga aattggaaac catcgacttc aagtcaggtc ctgaaaaaat
    10321 cacaacagcc atcgaagcag gaacagctcc agacgtactc tttgatgcac caggacgtat
    10381 catccaatac ggtaaaaacg gtaaattggc tgagttgaat gacctcttca cagatgaatt
    10441 tgttaaagat gtcaacaatg aaaacatcgt acaagcaagt aaagctggag acaaggctta
    10501 tatgtatccg attagttctg ccccattcta catggcaatg aacaagaaaa tgttagaaga
    10561 tgctggagta gcaaaccttg taaaagaagg ttggacaact gatgattttg aaaaagtatt
    10621 gaaagcactt aaagacaagg gttacacacc aggttcattg ttcagttctg gtcaaggggg
    10681 agaccaagga acacgtgcct ttatctctaa cctttatagc ggttctgtaa cagatgaaaa
    10741 agttagcaaa tatacaactg atgatcctaa attcgtcaaa ggtcttgaaa aagcaactag
    10801 ctggattaaa gacaatttga tcaataatgg ttcacaattt gacggtgggg cagatatcca
    10861 aaactttgcc aatggtcaaa catcttacac aatcctttgg gcaccagctc aaaatggtat
    10921 ccaagctaaa cttttagaag caagtaaggt agaagtggta gaagtaccat tcccatcaga
    10981 cgaaggtaag ccagctcttg aataccttgt aaacgggttt gcagtattca acaataaaga
    11041 cgacaagaaa gtcgctgcat ctaagaaatt catccagttt atcgcagatg acaaggagtg
    11101 gggacctaaa gacgtagttc gtacaggtgc tttcccagtc cgtacttcat ttggaaaact
    11161 ttatgaagac aaacgcatgg aaacaatcag cggctggact caatactact caccatacta
    11221 caacactatt gatggatttg ctgaaatgag aacactttgg ttcccaatgt tgcaatctgt
    11281 atcaaatggt gacgaaaaac cagcagatgc tttgaaagcc ttcactgaaa aagcgaacga
    11341 aacaatcaaa aaagctatga aacaatagtc cttagttatt ctataaaaag tagtttttta
    11401 aagaacctaa gagtgtatac ccccttttcc ctctacacag atagtgtaag aaaagggggc
    11461 ttttgtttaa aatgtaagaa actgtcacga aattaaaatg aagttcttac ataagcgaat
    11521 cataaaaaat ttcattttga ttttaaaaca gttcaagaaa gtcaaaaaat tattctattt
    11581 gaaagagagg tgccgactgt gaaagtcaat aaaatccgta tgcgggaaac agtgatttcc
    11641 tacgctttcc tagcaccagt attattcttc tttgtcatct ttgtgttggc tccgatggtg
    11701 atgggcttca ttacaagttt ctttaactac tcaatgacta aatttgagtt tgtaggcttg
    11761 gataactata tccgtatgtt taaagatcct gtctttacaa aatctctgat taacacagtt
    11821 attttggtta ttggatctgt accagttgtt gttctattct cactctttgt agcatctcag
    11881 acctatcatc aaaatgtcat tgccagatcc ttctaccgtt tcgtcttctt ccttcctgtt
    11941 gtaacgggta gtgttgccgt gacagttgtt tggaaatgga tttatgaccc actatcaggg
    12001 attctaaact ttgtccttaa gtccagccac atcatcagcc aaaacatttc ttggttggga
    12061 gataaaaact gggcattgat ggcgattatg attattctct tgaccacttc agttggtcag
    12121 cccatcatcc tttatatcgc tgccatgggg aatattgaca attcactggt tgaagcggcg
    12181 cgtgttgatg gtgcaactga gtttcaagtt ttttggaaga ttaaatggcc aagccttctt
    12241 ccaacaactc tttatattgc aatcatcaca acaattaact cattccagtg ttttgccttg
    12301 attcagcttt tgacatctgg tggtccaaac tactcaacaa gtaccttgat gtactacctt
    12361 tacgaaaaag ccttccaatt gacagaatac ggctatgcca acacaattgg tgtcttcttg
    12421 gcaatcatga ttgctatcgt aagctttgtt caatttaaag tacttggaaa cgacgtagaa
    12481 tactaaagaa aggagacagc tatgcaatct acagaaaaaa aaccattaac agcctttact
    12541 gttatttcaa caatcatttt gctcttgttg actgtgctgt tcatctttcc attctactgg
    12601 attttgacag gggcattcaa atcacaacct gatacaattg ttattcctcc tcagtggttc
    12661 cctaaaatgc caaccatgga aaacttccaa caactcatgg tgcagaaccc tgccttgcaa
    12721 tggatgtgga actcagtatt tatctcattg gtaaccatgt tcttagtctg tgcaacctca
    12781 tctctagcag gttatgtatt ggctaaaaaa cgtttctatg gtcaacgcat tctatttgct
    12841 atctttatcg ctgctatggc gcttccaaaa caagttgtcc ttgtaccatt ggtacgtatc
    12901 gtcaacttca tgggaatcca cgatactctc tgggcagtta tcttgccttt gattggatgg
    12961 ccattcggtg tcttcctcat gaaacagttc agtgaaaata tccctacaga gttgcttgaa
    13021 tcagctaaaa tcgacggttg tggtgagatt cgtaccttct ggagtgtagc cttcccgatt
    13081 gtgaaaccag ggtttgcagc ccttgcaatc tttaccttca tcaatacttg gaatgactac
    13141 ttcatgcaat tggtaatgtt gacttcacgt aacaatttga ccatctcact tggggttgcg
    13201 accatgcagg ctgaaatggc aaccaactat ggtttgatta tggcaggagc tgcccttgct
    13261 gctgttccaa tcgtcacagt cttcctagtc ttccaaaaat ccttcacaca gggtattact
    13321 atgggagcgg tcaaaggata atactctgag aaaatctctt caaactacgt cagcgtcacc
    13381 ttgccatact taagtattgc ctgcggttag cttcctagtt tgttcttcaa ttttcattga
    13441 gtataggaaa atcaatctat caagatacag aagtatattt tatagattta gagaatatag
    13501 aggttataag tgtctacaaa atggagggta tgcagttact ttatgaagtt ttgtcagaca
    13561 cttataaact taagaatggt tttagttaac tatcagaaac gaaggaaaga gtatgatttt
    13621 tgacgatttg aaaaacatca ccttttacaa agggattcat cccaatttag acaaggctat
    13681 cgactatctc taccaacatc gtaaagattc attcgaatta ggaaagtatg agattgatgg
    13741 agataaagtc tttctagttg ttcaggaaaa tgtcctcaat caagttgaga ataatcgatt
    13801 tgaacaccat aagaactatg cagatttgca tttgctgata gaagggcatg aatattcgag
    13861 ctacggttca cgtatcaaag acgaggcagt agcattcgac gaagcgagtg acattggctt
    13921 tgttcattgt catgaacact acccactctt gttgggttat cacaattttg cgattttctt
    13981 cccaggtgag ccacatcagc caaatggtta tgcaggcatg gaagaaaagg ttcgaaaata
    14041 tctctttaaa attttgattg attaaaaata ggatgaattg tttttttgta aagctttgat
    14101 aatactctac catgaaattg atctttgtga ggtagagaaa tgagaataaa atatttaaaa
    14161 attggtatct tctaagtatg ctgcaagagc tagtttctta gatggacagg ggattacagt
    14221 tgatgagatg gcttggataa ttaggggcat tgtgactgca ttgattggta gatacataaa
    14281 attaggtact tatgcagtta agtatggtat tagtatggcg cgctcgatct taagtagggc
    14341 agctgcaact gcggcagcaa gagtaggatt attgactaag atttttggat ggattttacg
    14401 aatagctgtg ctcgcagctg atgtatatgg taattttgcc aacaatattg ctgtagcttg
    14461 ggatgcacat gataaaatcc ctaacaatgg tcgtataaac ttttaaaatg cgagaatgaa
    14521 agcactttgt atttttttat tgtatatgtt agcttggaca gtgcttgcaa tgataatccg
    14581 tggagggcta gatggatttg atgaacacac ttggcgtact attttaattg cttcgctgtc
    14641 cgggatatat atagattata tgtccataga taaaagtaga aaaaagtcca aaagaaaaaa
    14701 gaaaaaatag atttgttcat ggtagggact tatgaaagct ttactgacaa aaaagaaaac
    14761 agtttacaaa gaaaaatgat ggaggagcaa acatggcaca aaaaggagta agccttatca
    14821 aggcagcatt tgatacagat aactttctca tgcgttttag tgagaaagtc ttggacatcg
    14881 tgacagccaa tcttcttttt gtcgtctctt gtttgcccat cgtgacgatt ggagtggcta
    14941 aaatcagcct ctacgagacc atgttcgaag ttaagaagag cagacgggtg cctgttttta
    15001 aaatctatct aagatctttc aagcaaaatc tgaaactagg tcttcagctg ggtttaatgg
    15061 agttaggaat tgtgtttctt accctttcag atctctatct tttctggggt caaacagctc
    15121 tgcccttcca attgctgaaa gccatttgtc taggcattct gattttcctt acgattgtga
    15181 tgttggctag ctatccaatc gcggcacgtt atgatttaac ttggaaagaa gtgttacaaa
    15241 aagggcttat cttggctagt tttaactttc cttggttctt cctcatgtta gccattcttg
    15301 tcctcattgt gatggttctt tatctgtccg ccttcagtct actcttaggt ggctcagtct
    15361 tcctactttt tgggtttgga ctattggtct ttatccagac tggattgatg gagaaaattt
    15421 tcgcaaaata ccaataggag ccttatttct gaaactactt tcaaaggctc caaacgctat
    15481 tctataagcg agaaactaaa atctaagtgt ctataagata ttgaaagcct tttcggtaaa
    15541 gtgtatacta aagaagtaaa gaaaaatctg ctttagcaga aaataaaaat aataggagaa
    15601 aatctatgtc agatttgaaa aaatacgaag gtgtcattcc agccttctac gcatgttatg
    15661 atgagcaagg agaagtaagt ccagagcgta cgcgtgcctt ggttcaatac ttcattgata
    15721 aaggtgttca aggtctttat gtcaatggtt cttctggtga atgtatctac caaagcgttg
    15781 aagatcgcaa gttgattttg gaagaagtca tggcggtagc caaaggtaaa ttgaccatta
    15841 ttgcccatgt tgcttgcaat aatactaaag atagtatgga acttgctcgc catgctgaaa
    15901 gcttgggagt agatgctatt gcaacgattc caccaattta cttccgcttg ccagaatact
    15961 cagttgccaa atactggaac gatattagtt ctgcagctcc aaacacagac tacgtgattt
    16021 acaacattcc tcaattggca ggggttgctt tgacttcaag cctttacaca gaaatgttga
    16081 aaaatcctcg tgttatcggt gttaagaact cttcaatgcc agttcaagat atccaaacct
    16141 ttgtcagcct tggcggggaa gaccatattg tctttaacgg tccagatgaa cagttcctag
    16201 gtggccgcct catgggtgct aaggctggta tcggtggtac ttatggtgct atgccagaac
    16261 tcttcttgaa actcaatcag ttgattgcgg ataaagattt agaaacagcg cgtgaattgc
    16321 agtatgctat caacgcaatc attggtaaac tcactgctgc acatggaaat atgtacggtg
    16381 tcatcaaaga agttttgaag atcaatgaag gcttgaatat tggttctgtt cgttcaccat
    16441 tgacaccagt gactgaagac gatcgtccag ttgtagaagc ggctgcagcc ttgattcgtg
    16501 aaaccaagga gcgcttcctc taatctaaaa ggaggtattt atgacatact acgttgcaat
    16561 tgatatcggt ggaactaaca tcaagtatgg tttggttgat caagaggggc aacttcttga
    16621 atcacatgaa atgccaacag aggcgcataa gggtggacct catatcttac aaaagaccaa
    16681 agatatcgta gctagttatt tagaaaaagg cccagtagca ggtgttgcca tatcttctgc
    16741 tgggatggtg gatccggata agggtgagat tttctatgct gggccgcaaa tccctaacta
    16801 cgcaggcacc cagttcaaaa aggaaatcga agaaagcttt actattcctt gtgagattga
    16861 aaatgatgtc aactgtgcag gtcttgctga ggcagtatct ggttcaggca agggagcaag
    16921 tgtgacactt tgcttgacca ttggaaccgg tatcggtggt tgcttgatta tggataggaa
    16981 agtcttccat ggttttagta attcagcctg tgaagtcggg tatatgcata tgcaggatgg
    17041 agcttttcag gatctcgctt ctacaacagc tttagtgaaa tatgtagctg aagcccatgg
    17101 agaagatgtt gatcagtgga atggccgacg tatctttaag gaagctactg aaggaaacaa
    17161 aatctgcatg gaaggtattg accgtatggt tgactatcta ggaaaaggtc tggcaaatat
    17221 ttgctacgtt gccaatccag aagtggtcat tcttggtggt ggtatcatgg ggcaagaggc
    17281 tatcctcaaa cctaagatcc gcacagcctt gaaagaggct ttggtaccaa gtttagcaga
    17341 aaaaacacga ttagaatttg cccatcacca aaatacagca gggatgttgg gtgcatatta
    17401 tcattttaag acaaaacaat cctagtttgg ctcagccaaa ctaggatttt cttacacgtt
    17461 tttgtctacg atagccgttg agttttttat tttcccagta gctattaaag attttttcct
    17521 tgctttcgcg attgatttcc aaaaagtagg cataaatcaa atcgataaag aagagcatag
    17581 gaagttgagc ggatattcgt tggatatagg agggttggct gtgggtggct acaagaacag
    17641 tctctgtata ggtctggcta tttttattgg gaacacttgt aaagagtaca gtctttgccc
    17701 ccatctcctt ggcatctaat agactatcta aaatagaagg agttgagcct gaaagtgaga
    17761 agcccagtac tagacaattt tcatccatga tgctggttgt ccaggcaaag ccgtcttggt
    17821 ctgtcaaagc ttcgcagacc acacctaatc gcataaaacg taatttcatt tcacgggcga
    17881 cgaggccaga actccctgtt ccaaagaagt agatacgctc agcatcttcg attagctggg
    17941 caattcgttc tagttggatt tcgtcaatca agtcttgtgt ttgttccctc atattgctat
    18001 aacttctgag gactcgtttg gtcagtggac tgtgcttgga aacttggttg gcttgatttt
    18061 ctgcctgatg ttggtattgg aaaataaatt ctcggtagcc agtaaagcca cactttttag
    18121 caaagcgggt caaagcagct tgagaaatat gtaatttttg ggtgacttgt tgagaagata
    18181 aatcatctgt aatcgtttca gcttgcaaaa aatagcgagc gatttcttgc tctaggtctg
    18241 tcatttcttc aaaatgtgaa tcaatgatag ttgcgatatc tggtttgtcc atagggaaag
    18301 ctcctttaca tgagtcatac tggaagacta gatcagggaa tagtcacact tcattataac
    18361 acataatata aggatagata aataaaaacg catctctgtt ttaaaaacga aaaaatcgaa
    18421 aaagcttctc tcttttccat aattttctac tcaaattgtg gtacaattaa gagtaagatt
    18481 ttaagttaga aatgagactg atttgtatga gaaaatttaa cagccattcg attccgattc
    18541 ggcttaattt attgttttca atcgtcattt tactctttat gaccattatt ggtcgtttgt
    18601 tgtatatgca ggttttgaac aaggattttt acgaaaaaaa gctagcctca gctagtcaga
    18661 ccaagattac aagcagttca gcccgtgggg aaatttatga tgctagtgga aaacctttgg
    18721 tagaaaatac gttaaagcag gttgtttcct ttacgcgtag caataaaatg acggctacag
    18781 acttaaaaga aacagctaaa aagttactga cttatgtgag catcagttct ccaaatttga
    18841 cagaacgcca gctggcggat tactatttgg ctgatcctga aatctataaa aaaatagtgg
    18901 aagctctccc aagcgagaaa cgcttggatt cagatggcaa tcgtctatcc gaatcagaac
    18961 tgtataacaa tgcggtcgat agtgtacaaa cgagtcaact aaactataca gaggatgaaa
    19021 agaaagaaat ctatcttttt agtcagttaa atgctgttgg aaactttgcg acaggaacca
    19081 ttgctacaga tcctctaaat gattctcagg tggctgttat tgcctctatt tcaaaggaga
    19141 tgcctggcat tagtatttct acttcttggg atagaaaggt tttggaaact tccctttctt
    19201 ctatagttgg gagtgtatcc agtgaaaaag ctggtctccc agcggaagaa gcagaagcct
    19261 atcttaaaaa aggctattct ctaaatgatc gtgtaggaac ctcctatttg gaaaagcaat
    19321 atgaagagac cttacaagga aaacgctcgg taaaagaaat ccatctggat aaatatggca
    19381 atatggaaag cgtggataca attgaggaag gtagtaaggg aaacaatatc aaactgacca
    19441 ttgatttggc tttccaagat agcgtggatg ctttactgaa aagttatttc aattctgagc
    19501 tagaaaatgg tggagccaag tattctgaag gtgtctatgc agtcgccctt aacccaaaaa
    19561 caggtgcggt tttgtctatg tcagggatta aacatgactt gaaaacggga gagttgacgc
    19621 ctgattcctt gggaacggta accaatgtct ttgttccagg ttcggttgtc aaggcggcga
    19681 ccatcagctc aggttgggaa aatggagtct tgtcaggaaa ccagaccttg acagaccagt
    19741 ccattgtctt ccaaggttca gctcccatca attcttggta tactcaggct tacggttcat
    19801 tccctatcac agcggtccaa gctctggagt attcatcaaa tacctatatg gtccaaacag
    19861 ccttaggtct tatggggcaa acctatcaac ccaatatgtt tgtcggcacc agcaatctag
    19921 agtctgctat ggagaaactg cgttcaacct ttggcgaata tggcttgggt actgcgacag
    19981 gaattgacct accagatgaa tctactggat ttgttcccaa agagtatagc tttgctaatt
    20041 acattactaa tgcctttggg cagtttgata actatacgcc gatgcagttg gctcagtatg
    20101 tagcaactat tgcaaataat ggtgttcgtg tggctcctcg tattgttgaa ggcatttatg
    20161 gtaataatga taagggagga ctgggtgact tgattcagca actgcaaccg acagagatga
    20221 ataaggtcaa tatatccgac tccgatatga gcatcttgca ccaaggtttt tatcaggttg
    20281 cccatggtac tagtggattg acaactggac gtgccttttc aaatggtgcc ttggtatcca
    20341 ttagcggaaa aacaggtaca gccgaaagct atgtggcaga tggtcagcaa gcaaccaata
    20401 ccaatgcggt ggcctatgcc ccatctgata atccccaaat cgctgtcgca gtggtctttc
    20461 ctcataatac caatctaaca aatggtgtag gaccttccat tgcgcgtgac attatcaatc
    20521 tgtatcaaaa ataccatcca atgaactaga aaggaaatta tgctttatcc aacacctatt
    20581 gccaagttga ttgacagtta ttctaagtta ccaggtatcg ggattaagac ggctacgcgt
    20641 ctggcctttt atacgattgg gatgtctgct gatgatgtca atgaatttgc aaaaaatctc
    20701 ctttctgcta agagagaatt gacatattgt tctatttgtg gacgtttgac agacgacgat
    20761 ccttgttcta tctgtactga ttcgactcgt gaccagacaa caattttagt tcttgaggat
    20821 agtagagatg tggcagccat ggaaaatatc caagaatacc atggactcta tcatgtcctg
    20881 catggcctca tttctcctat gaatggtatc agtccggacg atatcaatct taagagcctt
    20941 atgactcgtc ttatggatag tgaggtttca gaagtgattg tggcgactaa tgctacagcg
    21001 gatggtgaag cgacctccat gtatctttca cgtttgctca agccggctgg tatcaaggtt
    21061 acgcgtctag cacgaggtct cgctgtggga gcggacattg agtatgcgga cgaagtgaca
    21121 ctcttacgag cgattgaaaa tcggacagag ttgtaagtgt aggcaaattt acgaactcca
    21181 ttcatttata aaaaatcaaa gaggctgaaa atcgttccta tcggcctctt tttgtatagt
    21241 gtgatgagta gaatcaggtt caagttttaa aaaaccaagc aaatatgata tactaaagag
    21301 cgagtattct agtagaatta ggacaaataa tatgaaacaa acgattattc ttttatatgg
    21361 tggacggagt gcggaacgcg aagtctctgt cctttcagct gagagtgtca tgcgtgcggt
    21421 caattacgac cgtttcacag tcaagacttt ctttatcagt cagtcaggtg actctatcaa
    21481 aacgcaggaa tttagtcatg ctccggggca agaagaccgt ctcatgacca atgaaaccat
    21541 tgattgggat aagaaagttg caccaagtgc tatctacgaa gaaggtgcag tggtctttcc
    21601 agtccttcac gggccaatgg gagaagatgg ctctgttcaa ggattcttgg aagttttgaa
    21661 aatgccttac gttggttgca acattttgtc atcaagtctt gccatggata aaatcacgac
    21721 taagcgtgtt ctggaatctg ctggtattgc ccaagttcct tatgtggcta tcgttgaagg
    21781 cgatgatgtg actgctaaaa tagctgaagt ggaagaaaaa ttggcttatc cagtcttcac
    21841 taagccgtca aacatggggt ctagtgtcgg tatttctaag tctgaaaacc aagaagaact
    21901 ccgtcaagcc ttaaaacttg ccttccgata tgacagccgt gtcttggttg agcaaggagt
    21961 gaatgcccgt gaaattgagg ttggcctctt gggtaactac gatgtcaaga gcacgctacc
    22021 tggagaagtt gtcaaggacg ttgcctttta tgactacgat gccaagtata ttgataacaa
    22081 ggttactatg gatattcctg ccaaaatcag tgatgatgtg gtggctgtca tgcgtcaaaa
    22141 tgcagaaaca gccttccgtg ccattggtgg ccttggtcta tctcgttgcg atttcttcta
    22201 tacagataag ggagagattt ttctcaacga gctcaatacc atgccaggtt tcacccagtg
    22261 gtctatgtac ccactacttt gggaaaatat ggggatcagc tacccagaac taatcgagcg
    22321 tttggttgac cttgccaagg aaagttttga caagcgcgaa gcgcatttga tataaaatga
    22381 aagagagggt agaagccaga accatcactg caaggtgact agagttctcg gacttcagcc
    22441 ctttttaaag gagtagaaat gaaattaaca atccatgaaa ttgcccaagt tgttggagcc
    22501 aaaaatgata tcagtatctt tgaggacact cagttagaaa aagctgagtt tgatagtcgt
    22561 ttgattggaa ctggagattt atttgtgcca cttaaaggtg cgcgtgatgg ccatgacttt
    22621 attgaaacag cctttgaaaa tggtgcagca gtaaccttgt ctgagaaaga ggtctcaaat
    22681 catccttaca ttttagtaga tgatgttttg acagcctttc aatccctagc atcctactat
    22741 cttgaaaaaa cgactgttga tgtctttgct gttacaggtt caaatggcaa gacaacgact
    22801 aaggatatgt tggcgcattt actgtcaaca agatacaaga cctacaaaac acaaggcaat
    22861 tacaataatg agattggcct tccttacaca gttcttcata tgcctgaagg aacagaaaag
    22921 ttggttttgg agatgggaca ggatcacttg ggagatattc atctcttgtc tgaattggct
    22981 cgtccaaaaa cagccatcgt gaccttggtt ggagaagctc atttggcctt tttcaaagat
    23041 cgttctgaga ttgctaaagg aaaaatgcaa attgcagacg gaatggcttc aggttccttg
    23101 cttttagcgc cggctgaccc tatcgtagag gactatttgc caattgataa aaaggtggtt
    23161 cgttttggtc aaggagcaga gctggaaatt actgacttgg ttgagcgtaa ggacagtctg
    23221 acctttaagg ctaatttctt ggaacaagcc cttgatttgc cagtaactgg caagtacaat
    23281 gcgacaaatg ctatgattgc atcctatgtt gccttgcaag aaggagtttc agaggagcaa
    23341 attcgtttgg cattccaaca tcttgaattg acgcgtaacc gtaccgagtg gaagaaagca
    23401 gccaatggag cagatatcct gtcagatgtt tacaatgcca atccaactgc tatgaaactg
    23461 attttagaga ctttctctgc cattccagcc aatgaaggtg gcaagaaaat tgcagtgttg
    23521 gcggatatga aggagcttgg tgaccagtct gttcaacttc ataatcagat gattttgagc
    23581 ctctccccag atgtgcttga tatcgttatt ttctatggag aagatattgc tcagttggct
    23641 caattggcca gtcaaatgtt tccaatcggc cacgtttact acttcaagaa aacagaagac
    23701 caggatcaat ttgaagacct agtcaagcag gttaaggaaa gccttggagc ctatgaccaa
    23761 atcttgctaa aaggttctaa ctctatgaat ctagccaaat tggtagaaag tttagaaaat
    23821 gaatgcaagt gattttgcta agtatcttca aagaatgatt gctcttacag atactggact
    23881 aacctttaca aaggatccgt ttgaccgtga gcgctacgaa gacttgcgaa gtctgttatc
    23941 tgaaatgttg aatcaggtat cagaccttga tgcagacgaa gtggcagaac tcttgaaacc
    24001 gacctccgct tatgcgactc ctttaatgga cgtccgtgct tggatagttg aggatgaaaa
    24061 aatttgtctg gttaggggac aaggagagaa tgattgggct ttgccaggtg gctttggcga
    24121 ggtcggttat tcaccaactg aaaatattct caaggaaatt gaagaagaaa ccggttttaa
    24181 agccaaagtt gaacgactac tagctgtttt tgataccaat cgtttccaac tacagagcaa
    24241 acaatatgca aagtttgttt ttgaatgtaa gcttctcgat ggacaatttc aagaaaatca
    24301 agaaatcgct gaccttcaat tttttgcaat tgaccaactg ccgaatttat ctgaaaaacg
    24361 cattaccaag gagcaaatag agcttctttg gcaggtttat caaggtcata gggggcaata
    24421 tcttgactaa gaagatgatt atcgtatttc taaatccatt tttaacaact agcatggtat
    24481 aataatatgc aggaaaattt tgaattatga ggaagactag atgaatttat gggatatttt
    24541 ctttacgact caggcaaccg agccgcccaa atttgacctt ttttggtatg ttagcctatt
    24601 tacgctctta gccttaacct tttatacagc ccatcgctat cgtgaaaata aggtttacca
    24661 acgatttttc caaatcttgc agactgttca gttaatcctt ctttatggtt ggtactgggt
    24721 caatcatatg ccactgtcag aaagcctacc cttttaccat tgccgtatgg ctatgtttgt
    24781 ggtactcttg cttcctggtc aatccaaata taaacaatac tttgcattat tgggaacatt
    24841 tgggacatta gcagcctttg tttatccagt gccagatgct tacccttttc cacatatcac
    24901 cattctatcc tttatctttg gtcatttagc actcttgggg aactctctag tttatctatt
    24961 gagacagtat aatgcgcgat tgctggatgt gaagggaatt tttctcatga cctttgccct
    25021 aaatgccttg atttttgtgg tcaatttggt gacaggtggc gattacggat ttttgacaaa
    25081 accgccattg gttggggatc acggtctagt agctaattat ttacttgttt caattgtgct
    25141 ggtagctact atcagtttga ctaagaaaat cttagaattc tttttagctc aagaagcaga
    25201 aaaaatgatt gcaaaggaag cttaacacag agctttcttt tttgctctta gagagttttt
    25261 acaagcagct tataaaataa gaatttctga atagacaaac tcaaaaaatg gctgggaaat
    25321 ttaggaaaaa agcaagcacg attaaatttt ttgtgttata atattttgtg aatagctatg
    25381 cctatgttta gctatggaat aatacgaagt gcgaaacttg gaagatagag aggaagcgat
    25441 gtaatggcta gagaaggctt ttttacaggt ctagatattg gaacaagctc tgtcaaggtg
    25501 cttgtggccg agcagagaaa tggtgaatta aatgtaattg gcgtgagtaa tgccaaaagt
    25561 aaaggtgtaa aggatggaat tattgttgat attgatgcag cagcaactgc tatcaagtca
    25621 gccatttccc aagcggaaga aaaggcaggc atttcgatta aatcagtgaa tgtcggcttg
    25681 cctggtaatc ttttgcaggt agaaccaact caggggatga ttccagtaac atctgatact
    25741 aaggaaatta cggatcaaga tgttgaaaat gttgtcaaat cagctttgac aaagagtatg
    25801 acacctgacc gtgaagtcat tacctttatt cctgaagaat ttattgtgga tggtttccaa
    25861 gggattcgtg acccacgtgg catgatgggg gttcgccttg aaatgcgtgg tttgctttat
    25921 acaggacctc gtactatctt gcacaatttg cgtaagacgg ttgagcgtgc aggtgttcag
    25981 gttgaaaatg ttatcatttc accactagca atggttcagt ctgttttgaa cgaaggggaa
    26041 cgtgaatttg gtgctacagt gattgatatg ggggcaggtc aaacgactgt cgctacaatc
    26101 cgtaatcaag aactccagtt cacacatatt ctccaagaag gtggagatta tgtaactaaa
    26161 gatatctcca aggttttgaa aacctctcgc aaattagcgg aaggcttaaa actgaattac
    26221 ggggaagcct atccgcctct tgcaagcaaa gaaaccttcc aagtagaggt tattggagaa
    26281 gtagaagcag tcgaagtgac ggaagcctac ttgtcagaaa ttatttctgc acgaatcaag
    26341 cacatccttg aacaaatcaa gcaagaatta gatagaaggc gtctattgga cctccctggt
    26401 ggtattgtct taatcggtgg gaatgccatt ttaccaggta tggttgagct tgctcaggaa
    26461 gtctttggcg tccgtgtcaa gctttatgtt ccaaatcaag ttggtatccg taatccagcc
    26521 tttgcgcatg tgattagttt atcagaattt gcgggtcaat taacagaagt taatcttttg
    26581 gctcagggag cgataaaagg tgagaatgac ttaagtcatc agccaattag ttttggtggg
    26641 atgctgcaaa aaacagctca gtttgtacaa tcaacgcctg ttcaaccagc tcctgctcca
    26701 gaagtagagc cggtggcgcc tacagaacca atggcggatt tccaacaagc ttcacaaaat
    26761 aaaccgaaat tagcagatcg tttccgtggc ttgatcggaa gcatgtttga cgaataaaga
    26821 ggaaaaataa attatgacat tttcatttga tacagctgct gctcaagggg cagtgattaa
    26881 agtaattggt gtcggtggag gtggtggcaa tgccatcaac cgtatggtcg acgaaggtgt
    26941 tacaggcgta gaatttatcg cagcaaacac agatgtacaa gcattgagta gtacaaaagc
    27001 tgagactgtt attcagttgg gacctaaatt gactcgtggt ttgggtgcag gaggtcaacc
    27061 tgaggttggt cgtaaagccg ctgaagaaag cgaagaaaca ctgacggaag ctattagtgg
    27121 tgccgatatg gtcttcatca ctgctggtat gggaggaggc tctggaactg gagctgctcc
    27181 tgttattgct cgtatcgcca aagatttagg tgcgcttaca gttggtgttg taacacgtcc
    27241 ctttggtttt gaaggaagta agcgtggaca atttgctgta gaaggaatca atcaacttcg
    27301 tgagcatgta gacactctat tgattatctc aaacaacaat ttgcttgaaa ttgttgataa
    27361 gaaaacaccg cttttggagg ctcttagcga agcggataac gttcttcgtc aaggtgttca
    27421 agggattacc gatttgatta ccaatccagg attgattaac cttgactttg ccgatgtgaa
    27481 aacggtaatg gcaaacaaag ggaatgctct tatgggtatt ggtatcggta gtggagaaga
    27541 acgtgtggta gaagcggcac gtaaggcaat ctattcacca cttcttgaaa caactattga
    27601 cggtgctgag gatgttatcg tcaacgttac tggtggtctt gacttaacct tgattgaggc
    27661 agaagaggct tcacaaattg tgaaccaggc agcaggtcaa ggagtgaaca tctggctcgg
    27721 tacttcaatt gatgaaagta tgcgtgatga aattcgtgta acagttgtcg caacgggtgt
    27781 tcgtcaagac cgcgtagaaa aggttgtggc tccacaagct agatctgcta ctaactaccg
    27841 tgagacagtg aaaccagctc attcacatgg ctttgatcgt cattttgata tggcagaaac
    27901 agttgaattg ccaaaacaaa atccacgtcg tttggaacca actcaggcat ctgcttttgg
    27961 tgattgggat cttcgccgtg aatcgattgt tcgtacaaca gattcagtcg tttctccagt
    28021 cgagcgcttt gaagccccaa tttcacaaga tgaagatgaa ttggatacac ctccattttt
    28081 caaaaatcgt taagtaaatg aatgtaaaag aaaatacaga acttgttttt cgagaagttg
    28141 cagaggctag tctgagtgct catcgagaga gtggttcggt ctctgtcatt gcagttacca
    28201 agtatgtaga tgtaccgaca gcggaagcct tgcttccgct aggtgttcat catatcggtg
    28261 aaaatcgtgt agataagttt ctggaaaaat atgaagcttt aaaagatcga gatgtgactt
    28321 ggcatttgat tggtaccttg caaagacgta aggtgaaaga tgtcattcaa tacgttgatt
    28381 atttccatgc attggactca gtaaagctag caggggaaat tcaaaaaaga agtgaccgag
    28441 tcatcaagtg tttccttcaa gtaaatattt ctaaagaaga aagcaaacac ggtttttcga
    28501 gagaggaact gctggaaatc ttgccagagt tagccagact agataagatt gaatatgttg
    28561 gtttaatgac gatggcacct tttgaggcta gcagtgagca gttgaaagag attttcaagg
    28621 cggcccaaga tttacaaaga gaaattcaag agaaacaaat tccaaatatg cctatgaccg
    28681 agttaagtat gggaatgagt cgtgattata aagaagcgat tcaattcggt tccacttttg
    28741 ttcgtatagg tacatcattt tttaagtagg agagaaccat gtctttaaaa gatagattcg
    28801 atagatttat agattatttt acggaggatg aggattcaag tctcccttat gaaaaaagag
    28861 atgagcctgt gtttactcca gtaaattctt cacaggaacc ggctctccca atgaatcaac
    28921 cttcacagtc ggctggtaca aaagagaaca atatcaccag acttcatgca agacaacagg
    28981 aattggcaaa tcagagtcag cgtgcaacgg ataaggtcat tatagatgtt cgttatccta
    29041 gaaaatatga ggatgcaaca gaaattgttg atttattggc aggaaacgaa agtatcttga
    29101 ttgattttca gtatatgaca gaggtgcagg ctcgtcgttg tttggactat ttggatggag
    29161 cttgtcatgt tttagctgga aatttgaaaa aggtagcttc taccatgtat ttgttgacac
    29221 cagttaatgt tattgtaaat gttgaagata tccgtttacc agatgaagat caacagggtg
    29281 agttcggttt tgatatgaag cgaaatagag tacgataatg atttttttaa ttcgtatgat
    29341 ttataatgca gtggatattt actccctgat tttggtagcc ttcgctgtca tgtcttggtt
    29401 tccaggtgcc tacgaatcca gtttaggtcg ttggattgta gcgttggtga aaccagtact
    29461 tgctcccttg caacgcctgc ctttacagat agcgggtctt gatttatctg tttgggtcgc
    29521 gattgttttg gttcgatttt taggagaaaa cctagtgcgt tttctggcga tgataggatg
    29581 aataaaggga tttatcagca tttctccata gaagatcgtc catttcttga caagggaatg
    29641 gaatggataa agaaggtaga agatagctat gctccttttt taactccttt tatcaatcct
    29701 catcaggaga agctattaaa gattttggcc aaaacctatg gtcttgcttg tagcagtagt
    29761 ggggaattcg tctcgagtga gtatgttcga gttttattat acccagatta tttccaacca
    29821 gagttttcag attttgaaat atctctccaa gaaattgtgt attccaataa atttgaacat
    29881 ttaacgcatg ctaagatttt agggacagtc atcaatcaat tagggattga acggaaactt
    29941 tttggagata tcctagtaga tgaagaacgg gcgcagatta tgattaatca gcagtttctt
    30001 cttctctttc aagatggact aaagaaaatt ggtcgtatac ctgtttcgct ggaggaacgt
    30061 cctttcaccg agaaaataga taagctagaa cagtatcgag aactggattt atctgtgtct
    30121 agttttcgat tagatgttct tttatcaaat gttttgaaac tatctaggaa tcaagcaaac
    30181 cagttgattg aaaagaaact tgtccaagta aattatcatg tggtagacaa atcagattac
    30241 actgttcaag ttggagactt gattagtgtg agaaaatttg gtcgcttgag attacttcaa
    30301 gataagggac aaacgaaaaa agagaagaaa aaaataaccg tccagttatt attaagtaag
    30361 tgaggaatag aatgccaatt acatcattag aaataaagga caagactttt ggaactcgat
    30421 tcagaggttt tgatccagaa gaagtcgatg aatttttaga tattgtggtt cgtgattacg
    30481 aagatcttgt gcgtgcgaat catgataaaa atttgcgtat taagagttta gaagagcgtt
    30541 tgtcttactt tgatgaaata aaagattcat tgagccagtc tgtattgatt gctcaggata
    30601 cagctgagag agtgaaacag gcggcgcatg aacgttcaaa caatatcatt catcaagcag
    30661 agcaagatgc gcaacgcttg ttggaagaag ctaaatataa ggcaaacgag attcttcgtc
    30721 aagcaactga taatgctaag aaagtcgctg ttgaaacaga agaattgaag aacaagagcc
    30781 gtgtcttcca ccaacgtctc aaatctacaa ttgagagtca gttggctatt gttgaatctt
    30841 cagattggga agatattctc cgtccaacag ctacttatct tcaaactagt gatgaagcct
    30901 ttaaagaagt ggttagcgaa gtacttggag aaccgattcc agctccaatt gaagaagaac
    30961 caattgatat gacacgtcag ttctctcaag cagaaatgga agaattacaa gctcgtattg
    31021 aggtagccga taaagaattg tctgaatttg aagctcagat taaacaggaa gtggaaactc
    31081 caactcctgt agtgagtcct caagttgaag aagagcctct gctcatccag ttggcccaat
    31141 gtatgaagaa ccagaagtag ctccagtgca tccgacaggt ccaacaccag ctacagaaac
    31201 tgttgattca gcaccaggat ttgaagcacc gcaagaatcc gttacaattt tataagaaac
    31261 gatgtgagaa caatatctta tccttatatt tccagcgagc aggagatggt gtgagtcctg
    31321 cattccctaa cgataagatt atcctctcaa aaactcaagt ctgaagctag taagatttga
    31381 cgtttcccac gttacgggat aagagggaga aagactaaat ctttttccga ataaaggtgg
    31441 taccacgatt ttcgtccttt ttggaagtcg tggtttttaa tttgttatta tttataaagg
    31501 agataccatg aaactcaaag atacccttaa tcttgggaaa acagctttcc caatgcgtgc
    31561 aggccttccg accaaagagc cagtttggca aaaggaatgg gaagatgcaa aactttacca
    31621 acgtcgtcaa gaactaaatg aagggaaacc gcattttgtc ttgcatgatg gccctccata
    31681 cgcaaacgga aatatccacg ttggacatgc catgaatcat atctcaaaag atatcatcat
    31741 tcgttctaag tctatgtcag gttttaacgc accttatatc ccaggttggg atactcatgg
    31801 tctgccaatc gagcaagttt tggcaaagca aggtgtgaag cgcaaagaaa tggacttggt
    31861 tgagtacttg aaactctgtc gtgagtacgc tctttctcaa gtttataaac aacgtgatga
    31921 tttcaaacgc ttggggatgt caggtgactg ggaaaattta tatgtgactt taactccaga
    31981 ctatgaagca gcccaaatcc gtgtctttgg tgagatggct aataagggtt atatctaccg
    32041 tggtgccaag ccagtttact ggtcatggtc atctgagtca gcccttgccg aagcggaaat
    32101 tgaataccat gatttggttt cgacttcact ttattatgcc aataaggtaa aagatggcaa
    32161 aggtatccta gatacagata cttatatcgt agtctggaca acaactccat ttaccatcac
    32221 agcttctcgt ggtttgactg ttggtgcaga tattgattac gttttggttc aacctgctag
    32281 tgaaactcgt aagtttgtcg ttgctgcaga attgttgact agcttgtctg agaaatttgg
    32341 ctgggctgat gttcaagtgt tggcaactta ccgtggtcaa gaactcaacc acatcgtaac
    32401 agaacaccca tgggatacag ctgtagatga gttggtaatc cttggtgatc acgttaccac
    32461 tgactctggt acaggtatcg tccatacagc ccctggtttt ggtgaggacg actacaatgt
    32521 tggtattgct aatggtcttg aagtcgcagt gactgttgac gaacgcggta tcatgatggc
    32581 gaatgctggt cctgagtttg aaggtcagtt ctacgacaag gttgtaccaa ctgttattga
    32641 aaaacttggt aacctccttc tagcccaaga agaaatctct cactcatacc catttgactg
    32701 gcgtactaag aaaccaatca tctggcgtgc agttccacaa tggtttgcct cagtttcaaa
    32761 attccgccaa gaaatcttgg atgctattga taaagttaaa ttccatacag aatggggtaa
    32821 agtacgtcta tataatatga ttcgtgaccg tggtgactgg gttatctctc gtcaacgtgc
    32881 ttggggtgtt ccacttccaa tcttctatgc agaagacggt acagctatca tgacagctga
    32941 gactattgaa catgtggcgc aactctttga agtacatggt tcaagcattt ggtgggaacg
    33001 tgatgccaaa gacctcttac cagaaggatt tacacatcca ggttctccaa atggggagtt
    33061 caagaaagaa acagatatta tggatgtatg gtttgactca ggttcatcat ggaatggtgt
    33121 tttggtaaat cgtccaaatc tgacttatcc agctgacctt taccttgaag gttctgacca
    33181 ataccgtggt tggttcaact catcactcat tacatctgtt gccaaccatg gcgtagcacc
    33241 ttacaaacaa atcttgtcac aaggttttac ccttgatggt aaaggtgaga agatgtctaa
    33301 atcacttgga aataccattg ctccaagtga tgttgaaaaa caatttggtg cagaaatctt
    33361 gcgtctctgg gtaacaagtg ttgactcaag caatgacgtg cgtatctcta tggatatttt
    33421 gagccaagtt tctgaaactt accgtaagat tcgtaacact cttcgtttct tgattgccaa
    33481 tacatctgac tttaacccag ctcaagatgt agtcgcttac gatgaacttc gttcagttga
    33541 taagtacatg actattcgct ttaaccagct tgtcaagacc attcgtgatg cctatgcgga
    33601 ctttgaattc ttgacaatct acaaggcctt ggtgaacttt atcaacgttg acttgtcagc
    33661 cttctacctt gattttgcca aagatgttgt ttacattgaa ggtgccaaat cattggaacg
    33721 ccgtcaaatg cagactgttt tctatgacat tcttgtcaaa atcaccaaac tcttgacacc
    33781 aatccttcct cacactgcgg aagaaatctg gtcatatctt gagtttgaag ctgaagactt
    33841 cgttcaattg tcagaattgc cagaagctca aacttttgct aatcaagaag aagtcttgga
    33901 tacatgggca gccttcatgg acttccgtgg acaagctcaa aaagccttgg aagaagctcg
    33961 taatgcaaaa gttatcggga aatcgcttga agcacacttg acagtttatc caaatgaagt
    34021 tgtgaaaact ctactcgaag cagtaaacag caatgtggct caacttttga tcgtgtcaga
    34081 cttgaccatc gcagaagggc cagctccaga agctgccctt agcttcgaag atgtagcctt
    34141 cacagttgaa cgcgctgcag gtcaagtatg tgaccgttgc cgtcgtatcg acccaacaac
    34201 agcagaacgc agctaccagg cagtcatctg tgaccactgt gcaagcatcg tagaagaaaa
    34261 ctttgcggaa gcagtcgcag aaggatttga agagaaataa ggttgaaaag tctaggcaaa
    34321 attcaatttg agaagaaaag acaactaatt ttatagtcta ttaaacgcat tgtatcacgt
    34381 ttttgaatac ctgatatgat gcgtttttta tttattttaa aaatttgcga ggtatgactt
    34441 tttatactca acaagaatca aagagaaact tagcaagcta acagtagtaa gataaaatag
    34501 gaatttgata ttagggataa
//
LOCUS       DBEJJV010000024        34241 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.024, whole genome shotgun sequence.
ACCESSION   DBEJJV010000024 DBEJJV010000000
VERSION     DBEJJV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 34241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34241
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.024"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(512..1201)
                     /gene="rplA"
                     /locus_tag="ACL3GT_001270"
     CDS             complement(512..1201)
                     /gene="rplA"
                     /locus_tag="ACL3GT_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HGR0516939.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKVKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1409..1834)
                     /gene="rplK"
                     /locus_tag="ACL3GT_001271"
     CDS             complement(1409..1834)
                     /gene="rplK"
                     /locus_tag="ACL3GT_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HGR0516940.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(1957..2673)
                     /gene="ldcB"
                     /locus_tag="ACL3GT_001272"
     CDS             complement(1957..2673)
                     /gene="ldcB"
                     /locus_tag="ACL3GT_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase LdcB/DacB"
                     /protein_id="HGR0516941.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(2691..3152)
                     /locus_tag="ACL3GT_001273"
     CDS             complement(2691..3152)
                     /locus_tag="ACL3GT_001273"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HGR0516942.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDYQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(3154..4191)
                     /locus_tag="ACL3GT_001274"
     CDS             complement(3154..4191)
                     /locus_tag="ACL3GT_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HGR0516943.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDTRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSEAVS"
     gene            complement(4289..5614)
                     /gene="brnQ"
                     /locus_tag="ACL3GT_001275"
     CDS             complement(4289..5614)
                     /gene="brnQ"
                     /locus_tag="ACL3GT_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HGR0516944.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRVLTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5785..6072)
                     /locus_tag="ACL3GT_001276"
                     /pseudo
     CDS             complement(5785..6072)
                     /locus_tag="ACL3GT_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(6232..6810)
                     /locus_tag="ACL3GT_001277"
     CDS             complement(6232..6810)
                     /locus_tag="ACL3GT_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HGR0516945.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6864..8264)
                     /gene="pepV"
                     /locus_tag="ACL3GT_001278"
     CDS             complement(6864..8264)
                     /gene="pepV"
                     /locus_tag="ACL3GT_001278"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HGR0516946.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGFKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8277..8882)
                     /locus_tag="ACL3GT_001279"
     CDS             complement(8277..8882)
                     /locus_tag="ACL3GT_001279"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HGR0516947.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9053..9853
                     /locus_tag="ACL3GT_001280"
     CDS             9053..9853
                     /locus_tag="ACL3GT_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0516948.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10037..10870)
                     /locus_tag="ACL3GT_001281"
                     /pseudo
     CDS             complement(10037..10870)
                     /locus_tag="ACL3GT_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
     gene            complement(10860..12707)
                     /gene="uvrC"
                     /locus_tag="ACL3GT_001282"
     CDS             complement(10860..12707)
                     /gene="uvrC"
                     /locus_tag="ACL3GT_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HGR0516949.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGSIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQTKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12747..13448)
                     /locus_tag="ACL3GT_001283"
     CDS             complement(12747..13448)
                     /locus_tag="ACL3GT_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M57 family metalloprotease"
                     /protein_id="HGR0516950.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLAGQ
                     FLSVTVRLNHYYLSNPHYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13527..14759)
                     /gene="murN"
                     /locus_tag="ACL3GT_001284"
     CDS             complement(13527..14759)
                     /gene="murN"
                     /locus_tag="ACL3GT_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HGR0516951.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEYFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14764..15984)
                     /gene="murM"
                     /locus_tag="ACL3GT_001285"
     CDS             complement(14764..15984)
                     /gene="murM"
                     /locus_tag="ACL3GT_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HGR0516952.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16096..16875)
                     /locus_tag="ACL3GT_001286"
     CDS             complement(16096..16875)
                     /locus_tag="ACL3GT_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0516953.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16944..18605)
                     /locus_tag="ACL3GT_001287"
     CDS             complement(16944..18605)
                     /locus_tag="ACL3GT_001287"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0516954.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18780..21002)
                     /gene="recJ"
                     /locus_tag="ACL3GT_001288"
     CDS             complement(18780..21002)
                     /gene="recJ"
                     /locus_tag="ACL3GT_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HGR0516955.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GGASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21279..22082
                     /locus_tag="ACL3GT_001289"
     CDS             21279..22082
                     /locus_tag="ACL3GT_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0516956.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     EVADRIIFMADGEVLVDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22122..22886
                     /locus_tag="ACL3GT_001290"
     CDS             22122..22886
                     /locus_tag="ACL3GT_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HGR0516957.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQGDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTALLDDSFKPSDYGIVTKKSNT
                     EFNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22899..23576
                     /locus_tag="ACL3GT_001291"
     CDS             22899..23576
                     /locus_tag="ACL3GT_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0516958.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23586..24245
                     /locus_tag="ACL3GT_001292"
     CDS             23586..24245
                     /locus_tag="ACL3GT_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0516959.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNSVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMSRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24541..25731
                     /locus_tag="ACL3GT_001293"
     CDS             24541..25731
                     /locus_tag="ACL3GT_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HGR0516960.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26052..26933)
                     /locus_tag="ACL3GT_001294"
     CDS             complement(26052..26933)
                     /locus_tag="ACL3GT_001294"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HGR0516961.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27074..28402)
                     /gene="vncS"
                     /locus_tag="ACL3GT_001295"
     CDS             complement(27074..28402)
                     /gene="vncS"
                     /locus_tag="ACL3GT_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HGR0516962.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIAFPKVAQD"
     gene            complement(28399..29055)
                     /gene="vncR"
                     /locus_tag="ACL3GT_001296"
     CDS             complement(28399..29055)
                     /gene="vncR"
                     /locus_tag="ACL3GT_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HGR0516963.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29104..29187)
                     /gene="pep27"
                     /locus_tag="ACL3GT_001297"
     CDS             complement(29104..29187)
                     /gene="pep27"
                     /locus_tag="ACL3GT_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HGR0516964.1"
                     /translation="MRKEFHNVLSSDQLLTDKRPARDYNRK"
     gene            complement(29367..30746)
                     /gene="vex3"
                     /locus_tag="ACL3GT_001298"
     CDS             complement(29367..30746)
                     /gene="vex3"
                     /locus_tag="ACL3GT_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HGR0516965.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30798..31445)
                     /gene="vex2"
                     /locus_tag="ACL3GT_001299"
     CDS             complement(30798..31445)
                     /gene="vex2"
                     /locus_tag="ACL3GT_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HGR0516966.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31458..32735)
                     /locus_tag="ACL3GT_001300"
     CDS             complement(31458..32735)
                     /locus_tag="ACL3GT_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0516967.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGNSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
     gene            complement(33092..33262)
                     /locus_tag="ACL3GT_001301"
                     /pseudo
     CDS             complement(33092..33262)
                     /locus_tag="ACL3GT_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron maturase-specific
                     domain-containing protein"
     gene            complement(33405..34004)
                     /locus_tag="ACL3GT_001302"
     CDS             complement(33405..34004)
                     /locus_tag="ACL3GT_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0516968.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNLSLYTTIDKTSDATALLKLKLNNVDNQPATEVLSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNYP
                     VGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
BASE COUNT         9672 a         7819 c         6338 g        10412 t
ORIGIN      
        1 accgtacgtg ccgttcggca tacggcggtt caactaactt ttaacgcatg tcgttcaagg
       61 taataatcca aacacgaaac cagtccacgt ttttcaagga ctggttttga tatagcacgt
      121 ttaagtaccg acttctgagc tactatagta gattgaaact agaatagtac acctctactt
      181 ctaaaacatt gttagaaatc gatttgactg tcctgaacga ttcgtcctat tcttatttca
      241 ttttattata attgatagtg gtcgccccag ccagatacct tatccgctat ataggcctta
      301 ttatcacgtt cctgttcgta gagccacgat ttcgctatcc cttcctctga cgattcttat
      361 ttccagcgtc agacttggga atcgctattg ggttcaccgg tagtaggtgc ccaccgagga
      421 cttacacctc agatatacga catgcccgtc gtacatcaaa aaaagttgag acatagtgtc
      481 ttcaactttt ttacattact ttaactactg attaaagtga gtttacgtca actttgatac
      541 caacaccttg agtagttgtg atagtcaagt ttgttacgta agttccttta gctgtagctg
      601 gttttacttt ttggattgtt tcgttgaaag ctttaaagtt ttcaaccaat ttttcagctt
      661 caaatgatac tttaccgatg attgcttgaa cgttacctgc acggtcagca cggtaagtga
      721 ttttaccacc tttagactct tcaactgctt tagcaacatc cattgttaca gtaccagttt
      781 tagggtttgg catcaagtta cgtggtccaa ggacacgtcc aagacgtcca acaagagcca
      841 tcatatcagg tgtagcgata actacgtcga agtccaacca accgtcgttg attttagcaa
      901 caaggtcatc ttcaccaaca aagtctgcac cagcagcttt tgcttcttca gcttttgcac
      961 cacgtgcgaa aacaagaaca cgtgaagttt taccagtacc gtttggcaat accattgctc
     1021 cacggatttg ttggtcagct tttttaacgt cgatgttcaa gttgtaagca acttctacag
     1081 ttgcatcaaa ttttgcaaag ttagtttctt ttgcaagtgc tacagcttct tctacactgt
     1141 atgcttttgt gctgtcgatt ttctcaagag cagcacgaag ttgtttgctt tttttagcca
     1201 ttttctattc tccttgtaag tggttcaatc gattttcatc tcccacgtca cttctcgaaa
     1261 tgatgaagtc ttgcgggttt tcagtctact atttttctct tcctacggcc ttaagctccc
     1321 ttgctgtatc caagtacaag cctcagtcac ttgcctagta tgaaaagcaa ctaatagact
     1381 gctgtgagat tttctactgt gttattgatt agtcaacaac agtgaatccc atagaacgag
     1441 cagtaccttc gatcatacgc attgcagact ctacgtttgc tgcgttcaaa tctggcatct
     1501 tagtttctgc aatttcttgt acttgtgcac gagtaactgt agcaacttta gttttattag
     1561 gtgtacctga tcctttttca acacctgcag cttttttcaa aagaacagca gctggtggtg
     1621 ttttcgtaac gaaagtaaat gatttatctt cgtaaactga gataacaact ggaatgatca
     1681 taccagcttg gtcagctgta cgagcgttga actcttttgt gaatcccatg atgttgatac
     1741 cagcttgacc aagagcaggt ccaaccggtg gagctggtgt agctttacca gcagggattt
     1801 gcaattttac aagtttttcg acttttttag ccatttttaa atcctccttt gtggttttgg
     1861 cggtaattag agatttttac ctcccacaag tatgctttac acataccttt ccattataca
     1921 ctatttatct aaaaatgcaa gagaaaactt tcatttttaa tcgacataat cgccgccttc
     1981 aaagccatag tactcttcca aactgagacc acttgcagca atttctttgg cttcttttcc
     2041 aacgtagcgg agatgccatt cttctgccat gtagccagtc tccttttcct tgcctttaag
     2101 atagcgaaca acaaagccat agtcagccgc atggtccaag agccactggg ctgccttttc
     2161 ttcagtaact aaatccccat ctgtcccaat caaatcaaaa gcaagacccg tctggtgttc
     2221 actgtaacct gggcgtgctg agtagcgatc tgctgcttcc ttaccatctt gattgacata
     2281 gtcttggtag agcttagcct gagtttcata actcctaaac ccactgtatt ggtcactgat
     2341 tggatagccc tcagcctgca tagctgcgat tagtttgagc aactctgcct tggctgttgg
     2401 attttctcct ggattgtaat cttttgacaa aggataacgt ttattagcta ggataatctc
     2461 atcgtatttc ccttggatac tataatagct ccctttattg ctaacttctg cctttttctg
     2521 actagaagct tgagatttgc tacctacagt tccttccggt tgactgcttt gctccgtttt
     2581 ttgagtgttt tcttcaactt tggttttttc ttgcgaacaa gctgcaaggg tcaatgctag
     2641 taaaccagat aaaatgacat atcttttttt catttctttc ttcctctctc ttaggccaaa
     2701 tacttctcca attcatgaga taagatttta atcatctctt ccagctctgg cgattgtact
     2761 tggcaatctt ctgccgccat ttcttcccag ggcacccacc agactgggcc acggccattc
     2821 aaaccgtgac tcttcatatc acctgctctt cggggaaaaa gatgccaatg agcgtgggca
     2881 tcgccatttc ctaggagttc aatattcatc ttttcagcct caaatgcttt ggcgactgct
     2941 tcttggacta aactcatttc ctctaaaaag cgaagtttta cagaagtttc catatgatgg
     3001 agttctgtga catgatcttt tgctaaaaat aaggtatagc ccttaaagta ttggtagtca
     3061 ccaataacaa catagcctgt ttctagttct tttacaaagt agggattttg cccagcttta
     3121 atgagttcga ttctctgaca gattaagcac attctatgat accgcctcgc tcttaagata
     3181 agcatcaacc atacgctcag tcgctattac tgaatcgatg tgggtgcgct cataagagtg
     3241 actggactca ataccagctc caagaagtgc atgcttgacc tctgcacctg ctgacatcgc
     3301 tgctgaagcg tccgatccgt aaaatggata gatgtcgagc ttaaatggaa tatcttgctc
     3361 tttagccaag gcaaccaagt gttgacggaa gtcatagtga taaggacctg aagcatcctt
     3421 gacacagata gatactgtgt actcatctgt ctgctggtca tctcccatag ctcccatatc
     3481 cacagccaga tattctacta cctgagcagg aatgttagaa ttagcaccat gtcctacttc
     3541 ttcaaaaact gaaaaagcaa aatgagttgt tactggcaat tcaatcttct ctttcttata
     3601 aatacgaagc aggttgagca aaatcgctgc gctgacctta tcatccaaat gacgagactt
     3661 gataaaacct gtatcagtca caacagttcg tgtatcgaag ctgataaaat caccgacctc
     3721 aatcccaaga gcacgagttt ctttttcatt gcttactttt acatccaaac gcacttccat
     3781 attgtcctgc gtgcgttctg cagttcctgc atccttgtag acatggcaag aagtttggtg
     3841 gatgaggatg gttcctgata ccttttgacc tgtgctagcc acatgaacgg tacagttttc
     3901 accttcaatc atgttccaag gaaaaccacc gatacggtcc aatttaagac gaccatctgg
     3961 tttgacagca cgaacaatag cacccagcgt atccacatgg gcagtcacat agcgatgttg
     4021 ctcatcattt tgacctttga tggtcacatt gacaccaccc ttagctgtgc gaactggctg
     4081 gtaaccaaaa ccttctagag tcttgactaa ataattcgaa atttcacgag tgaagcccgt
     4141 tggcgatgcg atggctgtca gttctttgat atattctact gtttgattca tttcttcacc
     4201 tctttcgcta cctattataa cacatttatc atcggataaa aaaagaaaat cactcctgta
     4261 gacttggcta caaaagtgat ttaagtgatt attccatttc aaaaacatcg ctttcttgct
     4321 tgtttggtag aaccaatgag agcaagattc caacaatggc tggcaccaac catgggagag
     4381 atgccttggc aaaaggaaga acgctaacaa gatttgcaag aaactcaacc ttaaacgagc
     4441 ttcctagtac gcttgcaatg gcaataactg taaccacagc aattgtcaac tgcatacctg
     4501 gttttgaaag ggcaacaaat ttgttgacaa tgacaatcat aacgatagca atcgtgattg
     4561 ggtacaagat aaccagtact ggaattgagt acttgataat cgcatcaaga cccaaattgg
     4621 caatagcaaa tccaatcaag gtaaaggctg tcgcataaac cttgtagctg atttgtggga
     4681 agcgctcatt aaagaactca gctgttgaca caatcaaacc aacagtcgtt gtgaagcagg
     4741 ttacggtaac catagctgca aggaagagtt gagctgttga gccaaagatt tcttgagtgg
     4801 cttgtgacaa gatgtaaaca cctggtgttc cacccttcat cgcttcagct ggtactggga
     4861 aatgatttcc aagaaaacct aaaccgatgt aaagagcgct gaaggcaagg gcaacaacga
     4921 taccaacaac ccaaatagtt gaaatgtatt ctttcttact tgaaaatcca agttgtttca
     4981 aggtttgaac tgcgattacg ctaaaggcca ctgaagcaag ggcgtccaag gtattgtaac
     5041 cttctaggaa acctgtacca aaggcagaag cttgataagc agctgaagca gcttgaggac
     5101 ttgttccacc atatttgata gctcccagaa cgaccaagat aacaatcaaa attgcaaaga
     5161 ctggcgttaa aacacgtcca atgcggtcta agatttttga tggattaagc gaaatcaaat
     5221 aggctgccgc aaaatacaga accgtaaata caatcaagcc aagtccttta tttgcatccg
     5281 acaaaagggg gctaatccct acttcgtaag ctgttgtagc agtacgtggg gtagcaaaga
     5341 atggaccgat tgacaagtaa agaactgaga ggtaaagagt cgcaaaccaa ggcgctatct
     5401 tcgttgaaat ctcgtagata tatcctttag gatttagcgt tccaataata agggtcaaga
     5461 cggcgatacc aacgcctgaa aagacaaaac ctgcgatggc aggaagaaaa tgttctccag
     5521 atagagcacc tagagaaggc ggaaaaatca agttccccgc accaaaaaat attccaaaca
     5581 ggagcaaacc tgttagggta ccttttttag ccataaaaat ctccttcata tttataaaat
     5641 actgacctag tataccacga ttaggagtct gaaaaaagca tcacgaggca aatattaaat
     5701 gttttcaatt ttcttaaaaa taagaattat ctaaaaataa aactctccta cccagtccac
     5761 accaagcagg agaaatgcaa aattttaaag ttcttcaaag gctaacatgc caccctggac
     5821 attgataaca ttataacctt gttctaacag gaattggcaa gcacgcgccg atctcattcc
     5881 agatttgcaa ataatataat gcaagcgatc tttgtccaat taatcataac tatcagccaa
     5941 ttgactaagc ggtaggttgt gggcacattc taaatgaaga gctgcaaact catccacttc
     6001 tctcacatcc actagagaaa gctggtcgtt ttggtaaagc tggtaaaatg cgtcaaaggc
     6061 tatttctttc attctttttc ttctaatact cttcgaaaat ctcttcaaac cacgtcagcg
     6121 tcgccttacc gtgcgtatgt taccgacttc gtcagtttta tctgcaacct caaagctgta
     6181 ctttgagcag cctacgacta gcttcctagt ttgctctttg attttcattg actataaaat
     6241 ggttttaatt ctttttttca aatctggcac tacttctgcc tcaaaccaag gatttttggc
     6301 catccagatt tgatttcgtg gtgatgggtg aactagcgga aaataggctg gcagatagtc
     6361 tttatagtgt ttcaccctct ccgttacctt cccactgatt ttctcctgta aatagtaggc
     6421 ttgggcatat tgcccaatca agagggttaa ctgaatatca ggcaattcct gtaagagctg
     6481 cggatgccat ttttctgcaa aacctgtacg aggcggaaga tcacccgact tgccatgtcc
     6541 tggaaagtag aaatccatag gcaaaacagc aaaataacct gaattgtaaa aggtatcttc
     6601 atccacacct agccagtccc gcaagcggtc accactttta tctttccagt aaaggcctgc
     6661 ttcttgagtt ttaagtcccg gagcctgacc gatgatattg atgcgagcag tttttggcgc
     6721 tgcaaagaga ggctcaatgc cacgctctgt atagctggca ttctgtgaat ccgccatgat
     6781 agcctgtttg attctttcga tttgagacat ctactttccc tccaaaaaga agtccaagca
     6841 taagatctca gacttctatc gttttatttg atcaattcgt aaatagcttc ggcatagatt
     6901 gctgctgctc ggaagagatc gtccaaggcg ataaattcat tggcttggtg catggtatca
     6961 attgagtctg ggaacatagc accataggca actccgcgct ctaacaagcg accaaaggtt
     7021 ccaccaccga tgacttgttc atgaccttta aagccagttt gtttttcata gatattcaac
     7081 aaggtttgca caagtggatc ttccattggc acatagtgag gcgtgtgacc gtgttcagac
     7141 aggctaacag aaacaactgg caagttttca aggattgact tgatttgttc tggacttgtt
     7201 ccttttggat agcggatgtt gagggcaatg gtattatcag cacttgtttc atcgaagcgg
     7261 aagacgccgg cattcataga aagagcaccc atcttttcat ccacatgagc aatcttaaga
     7321 ttttcaccct catgatcgtt caagagaatt ttacctgcga tgtcaaggta gtctttggct
     7381 ggaccagcaa agccaaactg actgaggaag agggcaaggt aagttgcgcc attgacacct
     7441 gaagcaggca tagcaccgtg ggctgattta ccaatgatcg tcaccttgta tttgccagct
     7501 tcttcttgga gttctcctct aagtttgtgt tctgcaacaa aggcatctag tttagcttgc
     7561 aagtcagcca agtcacctga aacgactgct gttgctgatt ctggtaccat attttcacgt
     7621 aaaccacctg taaagctgtg aagacgggca acacctgtat tttctcctgc aaagtggagg
     7681 tattccgtga tatttccttt ttcaccattg atgattggaa attcagcatc tggtgagaaa
     7741 ccgaaatctg gtttggcaag tcctacgtgc tcaaagtagt agtccatgtc tgcccagcct
     7801 gattcttcgt ctgttccaac gatgaagcga actttcttag aagttggaag acccaattct
     7861 ttgatgattt tcaaaccata gtaacaagct gttgtaggac ccttatcgtc cgaagccccg
     7921 cgcgcataaa ggcgaccatc tttgatagtt ggtgtgtaag ggtctgtgtc ccaaccgcta
     7981 ccagcaggca ccacatccat atgggcaaag attccgagaa cttcttctcc atcaccaaac
     8041 tcaaaatgtc ctgcatagtt atcaacattc ttagttgggt agccatcgcg gtctgcgatt
     8101 tcaaggaatt tctccaaggc ttttactgga ccaggcccaa atggatgctg ggcatcagcc
     8161 ttgctgtcat cacgttctga attgatttcc aaaaggctaa acaagtcagc caagaggtct
     8221 tctttgcgtt tttctacttc tgctgtaaaa tcaattgctg tcattttttc ttctttctat
     8281 cttttctcga tgatttcatc tactggcaag cggtagcttg gttccaattt ttcgtctgta
     8341 taacccactg tgatcaagag ttctgggcgg aaacggtctt cgatttccaa aacttcatta
     8401 acttttgatt tgtcaaaacc aagaataatg ttagaaccaa ttccttggtc tgtcaatgca
     8461 agaaccaagt tcatggcaac caaacctgca ttgagagcta ggtagtcgct gacttgttgt
     8521 tcattgtagc gtgcaaattc agctggcaaa tttttcatga agtattgaag ttgttcttct
     8581 gagaaattgt tagcaccacc aactcgggca atcttacgag cgcgtttggc aaggtctgta
     8641 tctgtaaata gggcaatggt tacaggtgct gatgatacct gctcaaagtt tgaaccataa
     8701 gccaactttg ccagttcagc atttttctca cgaacaacta caaatttcca aggctggctg
     8761 ttgtgggcgc ttggcgccaa ggttgcaatt tcgatagccg tacgcacatc ttttggatca
     8821 acaggcttat cagtgaaatg cttggtcgca tgacgttttt tatttaattc aagaaatttc
     8881 ataatcgatt tccttttcta attctactgc ttccattcta ccataatttg aaagagcttg
     8941 cagggatttt tcatgattaa gtttttctat cacagacata aaagatatat attggtttat
     9001 caggaaagtt tctgataaac tagcaagtac tttacatttg aatggagaca gtatgaaaaa
     9061 atttagccta ttactagcta tcctaccatt tttggttgcc tgtgggaatc aagctacacc
     9121 caaagagact agcgctcaaa agacaatcgt ccttgctaca gctggcgacg tgccaccatt
     9181 tgactacgaa gataaaggca atctgacagg cttcgatatc gaagttctaa aggcagtaga
     9241 tgaaaaactc agcgactacg agattcaatt tcaaagaacc gcctgggaaa gtatcttccc
     9301 aggacttgat tctggtcact atcaggctgc ggccaataat ttgagttaca caaaagagcg
     9361 tgctgaaaaa tacctttact cgcttccgat ttccaacaat cccctcgtcc ttgtcagcaa
     9421 caagaaaaat cctttgactt ctcttgacca gatcgctggt aaaacaacac aagaggatac
     9481 cggaacttct aacgctcaat tcatcaataa ctggaatcag aaacacactg ataatcccgc
     9541 tacaattaat ttttctggtg aggatattgg taaacgaatc ctagaccttg ctaacggaga
     9601 gtttgatttc ctagtttttg acaaggtatc cgttcaaaag attatcaagg accgtggttt
     9661 agacctctca gtcgttgatt taccttctgc agatagcccc agcaattata tcattttctc
     9721 aagcgaccaa aaagagttta aagagcaatt tgataaagcg ctcaaagaac tctatcaaga
     9781 cggaaccctt gaaaaactca gcaataccta tctaggtggt tcttacctcc cagatcaatc
     9841 tcagttacaa taacactctt cgaaaatctc ttcaaaccac gtcagcttta tctgcaacct
     9901 caaagctgtg ctttgagcaa cctacggcta gcttcctagt ttgctctttg attttcatat
     9961 tgagtataag atatattaaa agcgatggga tcagccaatc gcttttttag tttgcattgg
    10021 ttattttagg aaactcttac aaaaaatcaa aaaaattctt cacatcctct acatacctat
    10081 gcttttctat taagcttgct aatagttcca gattgtgcct ctgatagtta tcttcacgac
    10141 gtagttcttc atacatttcg ataaagggaa aacccttgga tttggcaaat tctaactcag
    10201 cctcgtaatc ataagcgact ttacgaaata ggatatttac caattcccca tcttcaacct
    10261 ctatcacggc atactgggca cggtgatttt ttaacgcctc ccaattaaaa tagggcatgc
    10321 caatcgaccc tggattgatg atttgttgcc cttgactacc ataacgaagc aactacttgt
    10381 gaacatgacc ataaactgcc acgtccgttt ccgcatctag cagttggtca aatttctctg
    10441 tatcattctc aactagcaag tcaccaccat agtttttgtc aggtaaatta tgagagatag
    10501 aaaagcgcaa tccgtcaatt tctttctttt ccagcaaagg caagcttcgt agccagacaa
    10561 tcgttgcagg atccattcgc tccatcaaat actgtgtcat acgcaagagc tgaacttcct
    10621 gtgggtcttc taagccatat tgcccatcta aagcctcaag gacacaatca tcccaattgc
    10681 ctcgaacact tgccgtgata ggaagttcct ttaacagagc gaccaagtca tttgcacctg
    10741 gaccagggag gaaaatgtct cccatgagcc aatattcact ggctccttga gttttagcat
    10801 ctgcaatcac tgcttctagc gccgtcgcat tgccatgaac atctgataaa attgcgattt
    10861 tatggtttat tgtggtttcc ttccgtttgg taatctactc tttcttccgc cacttgaagc
    10921 aagatttctg tttcctgcgg gttcaacttg gtttgcacag cctctgctac tgctcttggt
    10981 actccaactt cgacaatctc atccacactg gcttccttga ttttggtcag agacttgaag
    11041 tgcctcatga gattttgctt gcgtttaggt cccagaccat caatcccatc caattgagat
    11101 gagaaagaat ttttggagcg cagttggcgg tggaaggtaa tggcaaagcg gtggacctca
    11161 tcttgaatgc gttggaggag gaaaaattcc tgagaattgc gagacaagtc caccacttcc
    11221 agcggatctc caaagagcaa ttcatgggtt tggtgcttat cattcttttg cagacctgca
    11281 attggaatat ccaagcccag ttcttcttgg atgacttgct tagcaatatt gacttgacct
    11341 tgccccccat caatcacaat caaatctgga ggagtcaaag cctcacgctg tactcgacca
    11401 tagcgtctgc gaatgacctc tcgcatactg gcatagtcgt ctggcccgac tacggtcttg
    11461 attttatact tacggtaatc ttttttactt ggcctgccgt taacaaagac caccatggct
    11521 gaaacaggac tggtccccat gatgttggag ttatcgaagg actcgatgcg aactggagtc
    11581 ggaatttgga gcaaacgtcc tagattttca atagctcctt gggtcttttc gactgatttt
    11641 tctagcaggt taaatttctg ctccagacta acacgtgcat tttttatggc tagattgacc
    11701 agctgttttt tctctccacg ttggggtttg agaatcttgg tatccaccaa agccttgaca
    11761 gcttcttcgt caatatcctg cggaatcagt acctcattgg gaactaggtg agatttttct
    11821 tgatagaatt gtcccacata ggtcaagaaa tcctcatctg gatcattgaa gtaggggaag
    11881 agattgacat cgcgctcgat gagcttgccc tgacgaacaa agaaaacctg cacacacatc
    11941 cagcccttat ccacatagta gccaaagaca tcgcgatttt ggagatcctt agccatgacc
    12001 cgttgcttgg ttcgaagcgt tccaatagcc tgaatcaggt cacggtattc cgccgcacgt
    12061 tcaaactcca tagtctgggc tgccgctgcc attttgccct ttagctcatc aatgattttg
    12121 ttatcctgcc ctttcagaaa atcagaaacc tcctgggcca tagacttgaa ataagcctca
    12181 tccttcttac agatggtgtg agccatacac tggccgatat ggtaataaaa acagacctta
    12241 gagggcgggt tggtacactt acgaaaaggg aatatccgat ccagcaaccg cttgatttca
    12301 ttggctgccc ccacatcggg atagggtcca aaataaagac ctccgtcctt tttgacctga
    12361 cgagtgataa tcaagcgtgg atagcgctca ttggtgattt tgatgaaagg ataggacttg
    12421 tcatccttga gcatgatatt gtacttgggc ttgttttcct tgatcaggtt gatttctagg
    12481 agaagtgcct caatattaga ctccgtaaca ataaattcaa aatccacaat ttcagacacc
    12541 agagcctctg tcttggtatc atgacttcca cgaaaatagg accgtactcg attacgcaga
    12601 tttttagcct ttcctacata gataatggag ccatttttat ccttatgaat gtagcaacca
    12661 gggctggtcg gcaagagctc tagttttgat ttaatcaagt tgttcatagt tccattatag
    12721 caaaaaaagt agggaaagat agtaccctac tcactagtct catatatttt tcggaggttt
    12781 gcaacatcct cttcctggat accataaaag gaacctgctg gttgcatgac agacttctca
    12841 tctgtatggt ccaagccaat cgcatgacct aactcatgtt ctgccgtatg gacaaggcgt
    12901 tcataggagt agccatagtg tggattggac aaataataat gattcaaccg caccgttacg
    12961 gacaagaatt gccctgctaa gagattagtt tgactttccg cctctcctgc cacaggagtg
    13021 cctccgtcgt tcatctccgt agccgtaata tccgccttac tagactcagt cacgagttca
    13081 aagttaaaag caccagtttg attccagttc tggattgctt ctaaataagc ctcttgaaag
    13141 cgtgaatcca tctgcggatc caggtaaata cgagcagagg cctgtgccca ccttccttca
    13201 gaatgctggt gactatctgt ctggcttaac ttaggcagtt gccctgtttt ctcccattgg
    13261 tcaatacttt gttgaccaat ttttactgac cgttctgctt gctttagcgc tccttgaaaa
    13321 tccccgttca gataccagag aagtccgaaa gcaagcacac ataagagcac aactatccaa
    13381 accagacgcc aaaacaaacg ccacacaaaa gaaaagaaag cccctatcaa acgaaaaagc
    13441 cagcgcatgt ctctccacct ttctagcaaa taagaattat tttactaaaa gaagctaaaa
    13501 gaaatctaaa tactgacttt ttcatcttaa cgtcctacta tttttttgag taactggata
    13561 gctttgtatt ttaaaggcga tggatggtaa cggaaagtac ccgctttgcg tacaatatag
    13621 ccattaaaat tctgtttaaa acgcaaaaca ccatcacttc catcaaaaat cccttgaatg
    13681 cctaggaaat tgtatttagg tattccacgt tttatgcttt ccaacataac atatttttga
    13741 agcagtgcag gggcatagaa cttattaaac tcagtgtagg aaccactaaa gagataagtc
    13801 gtttcctgag gcatataaac aaataaactc ccagctaaaa caatatcttc ttctccatat
    13861 ttttcaatca agtctcgcgc ttctgctttt cgaacttcaa acgtttcaaa ttgactagaa
    13921 tattctctca gttgattttg ttttttctca gaatgaggat ttttactcaa atcaagtcgc
    13981 aacttgtcca agttttcttc tagtttactt tgttcacctt gcaatttgct catatactcc
    14041 gaaaaattca agcttgctat gagaaactcc gcttgttctc caaaagtatc ataaaaatac
    14101 tcataatatt ctaaactttt atcactatat tctctacgtt cagaggtttc ttttgttata
    14161 ttcttaaaaa tcgatagttc ttcacgtttt aactttttca accgaatgcc aaaggtttca
    14221 gcctttttca ccaagggttt accctttttg ctaaaacttt taagcaaact cttttcagtt
    14281 aattcagtta aatctttata gtataaccaa tctggttctc cacctgggta acctgttgtt
    14341 aagccatcaa attgataacc taaatcagtc aaaccttgaa taatactttt tttctcagca
    14401 tctattggat taccttggct atcaaaagtt tgataagttt cataaggttt tacaagcaac
    14461 tctaatacac cattttgctt ggcatattct tttaactctg cataaaaaac tggaagagca
    14521 tcttgttggg tataaatcgg ccccgaattg agttccatat gcagaccacc cagcatgggc
    14581 aggctataaa ccagagctgc aacttgaatt tctccttctt gtttcaaagc aagataaaca
    14641 attcgagccc ctcttttttc tagcaaatcc cccatctgga cagattgcat aaaggaacga
    14701 gaagaaacct gatcagaata agtctgaaac tcttctttcg tgagtgttgt tagtgccata
    14761 tacttacttt ctatgttttt ttcttaatgt tttacggaaa tcaagagcaa gtcttaacag
    14821 aggatagaga ggatgagtgg gcattgtaaa ttcacccaag tattcttcaa tcgttggatt
    14881 aaatttttcc ttaaaatgat aaagtccacc attgagagag ttttcaacac cacctaaatt
    14941 ttgccagacc atacctcgct caaaggcata gcgagccgtt tcataccatg ttaaaattgg
    15001 tgcattgtaa cgtttaaaat catcatccat accagcatat atattgacag aggtagtacc
    15061 aaattccaaa ctcaaagtag ccgctaaagg aactctcgct tgacctacat ctatatattc
    15121 ctgcaagaag gtcaattcct ctaacaaacg ttctttttcc ttcttctgcg cttctacttt
    15181 tgaagttcga gtcgactcag taaacgtctc ttccaaggct ctatttttcg ctaactgttc
    15241 ttctaactct tgcgaacgtt tagaaacatc caaggtggcc aaggtgatat aggccttgtc
    15301 cttaaaatta tctaacaatt ttttataata ggcttcattc ctcaaatgaa tctcttttcg
    15361 cttctcagtt tttttcatca actccgaaaa tgaatctaat agttccagtc caccatattg
    15421 aatctcaagc cctttgtttc gtgctgttcg aatagcctgt tttgttgact tggaaagttt
    15481 atcttcttca aaattttcct tgtatatttt cgcctgaata cgaggttgaa tggtgtctcc
    15541 catttcctcc gtttttcctg accaccttac tcccatttgt tgcaaactat caataatagc
    15601 cagattttca ggaaattctg tcttttcctg attgattaaa ctttgagata ggcaaatact
    15661 tgggtcaaaa gtcacaaaaa ccgctctctt actgcgagca taggacttaa tagactgaat
    15721 gacaaaattc aagagttctt tatccccata atccaatata ggtcctcttg ggatgtaaaa
    15781 cattttatag cctagcggaa gagttctaat caaaatacta gctgtcgcca gtaatttttc
    15841 ttccctgtaa acaccaaact tctcatgttg ccaattagac ttaacttcct cccaagcact
    15901 actttgtaat acattggcta attcatgttc tttgacaaac tgatcatatt ctaatgtggg
    15961 aatgccaatt tgataacggt acatttccta ctctctttcc tccagtattt tattactatt
    16021 ctactacttt cgtttgaaaa gtctagtgaa aacatatttt attttagttc tactccccct
    16081 atgctgaagt tcaaactaag tcagtctctc ttctaatttg aaatcaattg gtagggttgt
    16141 taaaaaaact tccaattgtt tttcccagta gtaccactcg tgagttccag cgctatggct
    16201 ataggtcaca tcaaaaccta gttttttgag atttttcact gcgagattat tggcttcgta
    16261 caagaaatcc tgttcgccac accacgccca aagtttggtc tttttatccg attttttagc
    16321 cagactttca agagaatagg gactagttgt ccagtcttta atctctccaa aaacacctct
    16381 ccagtaggct ggacttccca gattttgact ttcaggagaa aagttttgaa agctgagggc
    16441 acctgaaaag ctagctgcat gagaaaaacg atttgtcgca agagccagtt tgaagcagcc
    16501 gtagcctccc atagaaagac cagcgataaa ggtcttttca cgcttgctag tcatattagg
    16561 gaagaagcgt ttcagaacct gtggcaattc ctctgctaga gccgtgtagt agtcaaaacc
    16621 atactgggta tcggtgtacc aaccattgct ggtattgggc ataacaacga tgagattagt
    16681 tcctcgaagc aagcgttcta cattggtccg cttaagccaa ctattatgat ttccagacat
    16741 cccgtgcaaa aggtacaaga cgggaatatc ttcacactct ggttcttcca ctcgattggc
    16801 atcagggtag aggacattca ccccccactc catatccaat acttgtgagt aatactcgat
    16861 tttcattact gccatgattt tctccttcta tttttctata agaaaaagcc gaaactcgac
    16921 tttctctctg tttatttcaa cgattatttt gcttccatga ctactggtaa aatagctgga
    16981 cgacgcttgg tttggtcaaa gagatacttg gtcaaattat ctcgaacctt ccctttaaga
    17041 tctgcccagt caaagtcatc tccttgaaga tactcttcta ccgtttggtt aatcaattct
    17101 gaactttcac ggagaatatc gcgactcttc ttgagataaa caaatccgcg cgtatgaaca
    17161 cgagccctag ccacaatttt cttctcacga cggttgactg taatagccac gatgaaaatt
    17221 ccatcctctg acaagacctt acggtcacga agaacaacat ttccaacatc accaatggca
    17281 ttcccatcaa tcaagatatc tcctgctgaa accgatccag ctggaacaaa gtctccattc
    17341 tcgtaagcca tggtcgtccc ctttttagga atgaagatgt gttctggcaa catcccaact
    17401 gccatggcag ccttagcgtg agcatccaac tcacgatact ccccttggac agggaagagg
    17461 tacttaggtt gcaaaagatt gatcatcagc tgcaaatcac gcacatttcc gtgccctgat
    17521 acatgtaaac tttgggtaat caatttgaca accccacctg cctgataaat catattttcc
    17581 acacgcgcaa caaaggcttc tttagcaata gacggagccg tagcaatata gaccaggtcc
    17641 ccatccttga tttctacata acgatggcga ccaatcgaca tcttacgaag tccattgata
    17701 ggttcaccca tacgacctgt ctcaagaata atcaactcat ggtcttcaaa gcgagacata
    17761 tctttaggct taatcaagag aatttcgttg gctaaagaca acttcttaag acgaatcgct
    17821 gtgcggacga tattttcaat atcaaatcct gtcaagacga tacgtcgacc tgttttatcc
    17881 gcagcgtcaa aaatctgctg aatacgagaa agattactgg aaacagctgc aacgatgata
    17941 cgaccttccc agtcagcaat agtttgggta atttcatccc taacttcact ttcactagcc
    18001 acctgaatat tgctgtctgc attggccgaa tcactgagga gagccaggac gccgtcacga
    18061 ccaatctctg ccaaacgagc aaaatcagtt gcataagatt cactagccgt ttggtcaaat
    18121 ttgaagtcac ctgtataaac gatgcttcct tccgatgtct tcaagacaat tcccagactc
    18181 tctggaacgg agtaagtcgt agggaagaag gaaaccactg tcccaccaaa atcaatctcc
    18241 gtattctcat caatgacatg gaaatcatta aatttcttaa cggcatcatt tcctttgaca
    18301 aagagctttg ccaactcaat ggtcaactca gacccaaata caggaacttt agcctctgcc
    18361 aagagataag gtagagcacc aatggcatcc gcatgcccgt gggtcaagaa aaccccagca
    18421 atacggtcgc tattttcaaa aaggtaatcc atgtttggaa tcaccacatc gacccctaat
    18481 tgttcatttt caggatattt taaccctaca ttcaaaacaa aaatggactc tccaatttca
    18541 gcaatgtaca tattttttcc attctcacgc acaccaccaa gtgttgttaa actgatatta
    18601 ctcatttttc ctccaaaatc ttagtttatc ttgattatag ggcaactcta ccctcttatt
    18661 ctaaaagttc taatactttc agccgaatct tttcctacca ttataccatt tttttgatga
    18721 ttttcaaaat gaaggtctgt tttcaaaaaa gagttgattt cccaactctt tcctaacttc
    18781 tactcttttt ccatcaaaaa atcataaatt tcttgcaccg tacccagcgc catcatttct
    18841 tggtctttaa cggtttgttt gagattttgg taaatttgac tttctcctat ctcccgcttt
    18901 ggcgcctctt tattgactgt catcacacca tcttttatcg tcacaaagcc tagttcttca
    18961 aatacttgaa tcatcttgac cagcaagatt tgttgaatat taagatatgc agccaaatct
    19021 ttcagcttgt agcgaatatc aaactctggg aactggtaaa tagtcttgta caatttggca
    19081 aactgatctc tagtcccata acctgtcaga taataggcct tgtcaatatc atttttgaaa
    19141 tagacagcag agaaatgctg ttcctgaaaa atggtcttca gctgagtaat atcctctgga
    19201 atgtttttta cgacaatagc ttcactagcc gcaagatttg gcagttctcc aggaaaatcc
    19261 aagactggaa caccttctgg caagactgca ttttttccac gaatgttaaa aagttgaaca
    19321 ccttccactc gcgcatccac catcatcaac tggagggcag tttggccatt ccattggttg
    19381 acagacaatt taaccgctaa ctctagattc ttggtttgag aaaactctgt cgcccatctg
    19441 ccttgaccaa aggctaccac ttcaaaactc gccccaccct tggaaatttt cagctttaga
    19501 tgggcattac ctgcccccat agtacgagca ctttcgacct gaaaattctt gatataaaaa
    19561 ataggtttct gattatccat tccaaaagga gctaaacgtt caaaactttt gaccgtttcc
    19621 aagctaagtg cctccaaatc caactcttca tctaggttta acttattctt gccaccagca
    19681 tctgcacctt tttcacgaac ataatcttcc aaaacctgag ataaatctga gagttgctca
    19741 acttccagcg tcatacccgc tgcacctgca tgacctccaa aggcgatgaa gaggtctcga
    19801 tggggatcca gagcttcaaa aatatcgacc gcttccacac tacgagcact gcccttggca
    19861 cgaccgtctt ctatattaag aacaatgact gtctgtccca attcttccaa taaacgacca
    19921 gccacgattc ctagaacccc aggattccag ccttccttgg ccaagacctg aaccttcttc
    19981 tcaggatcca ccatggtctt ggcttcttca tagatagact gaacgatttc cttgcgctct
    20041 tcgtttttct ggtgaatcat aagggcaatc tcatgcgctt cctcatcatc aaatccagtc
    20101 aacaaatcaa tggcaggatt gggatcatcc aagcgaccca aggcattcaa acgaggagca
    20161 atctggaaac caaccgtttc ttctgttact tcgttggcag caatcccagc catgtccagc
    20221 atttcttgca gaccaatgcg ctgggtatga cccaacattt ccagaccata ttgaactaag
    20281 atacgatttt catccgtcag actcaccata tctgcaatag ttccaatagc gaccaaatca
    20341 agcaattcca cttgcacttc ttctaacagg gcacaagcca acttgaaagc aactccacaa
    20401 ccagccaaat atttaaaagg ataatccgca tctggatgtt caggatggac aatagcataa
    20461 gcatctggca gggtttcagg catggaatga tggtctgtca caatgacatc tactcccata
    20521 gactgagcca atgcaatagc ctcatgacca gcaaccccat tgtccaccgt cacaatcaag
    20581 gaaattcctt cttgctcgat aaagtattta taaacactag cattagggcc atagccatcg
    20641 gtaaaacgat ttggcaggta aactcggcac tccgcaccaa gttgttccaa actttccttc
    20701 acaatagaag ccgaagtcat gccatccgca tcgtagtctc cataaacgag aatattttcc
    20761 ctttcttcaa tagcctgacg aatccgctcc actgccttgt ccatatcatg gagcagataa
    20821 gcatcatgta agtcctccaa ggaaggttct aaaaacttct tcagactttc ttggtcctga
    20881 atccctctct caaacaataa ccgagccacc tcaggaccca gtccagcctt cttggctatc
    20941 tttgtaaaat ccgcatcttc tacctgcagg gcaaactgcc attcataagt aggtgttatc
    21001 aaaaagacat ccactccttc taagaattct attgcttcat tataacatga tttagacgtt
    21061 ttctctatcc agattgcttt tttataacat ttcatagtat attgaaacta gaatagtaca
    21121 cctctacttc taaaatattg ttagaaatcg atttgactgt cccgatcgat ttttcctgtt
    21181 cttatttcac tatagtgaat tttttcagat atggtttgac aagaacattc ttttattgca
    21241 gaattgtgtt ataaaatcta acataaagga gttctctcat ggctttagta gaatttaaaa
    21301 acgtcgaaaa atattacgga gactaccacg cactccgcaa catcaatctc cgttttgaaa
    21361 aaggacaagt tgttgtcctg cttggacctt ctggctctgg gaagtccact cttatccgta
    21421 cgatcaatgg tttagaggct gttgacaaag gaagtctcct agtcaatggg caccaagttg
    21481 ctggtgccag ccagaaagat ttggtacctc ttcgcaagga agtcggcatg gtttttcaac
    21541 attttaacct ttatccacac aaaacagtgt tagaaaacgt gacacttgca cccattaaag
    21601 ttctaggaat tgataaaaaa gaagctgaaa aaaccgccaa aaaatatctg gaatttgtaa
    21661 atatgtggga caagaaagat tcctatcccg ccatgctatc tggtggacaa aaacagcgga
    21721 tcgccatcgc tcgtggtctt gctatgcatc cggaactcct cctctttgat gaaccaacat
    21781 ctgctcttga tcctgagact atcggagatg ttctagcagt tatgcagaaa ctggcgcgtg
    21841 atgggatgaa catgatcatc gttacccacg aaatgggctt tgctcgagag gttgcggacc
    21901 gcattatctt tatggccgac ggagaagttt tagaggttgc ggaccgcatt atctttatgg
    21961 ccgacggaga agttttagta gatacgacag atgtcgataa cttttttgac aatccaagcg
    22021 aacctcgtgc ccaacaattc ctcagcaaaa ttatcaacca cgaaagtgac aaagtcaaat
    22081 aaggaggcgc ctatgaaaaa aaattctttt tatcagcatt attgattagc cttttcggcc
    22141 ttgctgctgc caaaccagtc caggctgata caagtatcgc agacattcaa aaaagaggcg
    22201 aactggttgt cggtgtcaaa caagacgttc ccaattttgg ttacaaagat cccaagaccg
    22261 gtacttattc tggtatcgaa accgacttgg ccaagatggt agctgatgaa ctcaaggtca
    22321 agattcgcta tgtgccggtt acagcacaaa cccgcggccc cctcctagac aatgaacagg
    22381 gcgatatgga tatcgcgacc tttaccatca cggacgaacg caaaaaactc tacaacttta
    22441 ccagtcccta ctacacagac gcttctggat ttttggtcaa taaatctgcc aaaatcaaaa
    22501 agattgagga cctaaacggc aaaaccatcg gagtcgccca aggttctatc acccaacgcc
    22561 tgattactga actgggtaaa aagaaaggtc tgaagtttaa attcgtcgaa cttggttcct
    22621 acccagaatt gattacttcc cttcacgctc atcgtatcga tgccttttcc gttgaccgct
    22681 ctattctatc tggctacact agtaaacgga cagcactact agatgatagt ttcaagccat
    22741 ctgactacgg tattgttacc aagaaatcaa atacagagtt caacgactat cttgataact
    22801 tggttactaa atggagcaag gatggtagtt tgcagaaact ttatgatcgt tacaagctca
    22861 aaccatctag ccatactgca gattaaggag gacaccccat gacagattta tcatcttgga
    22921 cagcctattt tcaggatttt ggacaatttt tcaatggttt cctcttcacc cttgccctag
    22981 cgattggatc ctttatcctc gccatggtct taggaatctt ctttggtgcc atgtcaacca
    23041 gtaaacgtcc aattttacgc attttagctc gcatctttgt ggaattttac caaaacactc
    23101 ccctcttggt gcagtttgtt attgtttttt atggcctacc tcttatcagt gaccatacta
    23161 tcatgattcc gatttattgg acagctgttc tctgcgtggg actctatcac ggcgcttata
    23221 tcgctgaggt tattcgttca gggattcagt ctattcctag tggtcagatg gaggccgcct
    23281 tatcgcaagg ttttacctat atcagtgcca tgcgcttgat tatcttgcct cagaccttcc
    23341 gcatcattct ccctccattg accaaccaaa ttgttaacct catcaagaac acctctactg
    23401 tagctatcat ctctggagta gacttgatgt ttgtgactaa gtcttggtcg gctctcaacg
    23461 gaaactatat cccagccttt ttaggtgctg ctcttctcta ctttgcccta tgcttccctg
    23521 ttgcccagtt tggtcgcaag atggagcaag ccaacaaaaa agcctattca ctttaggagg
    23581 ttactatgga atctatttta gaagttttaa ccccagataa cctagtcttt atctttaaag
    23641 gatttggctt gaccctctat atttctctga ttgccatcat cctctctact atcatcggta
    23701 cggtgctagc tgtcatgaga aatggcaaaa attctgtctt gcgaatcatc tccagtattt
    23761 atatcgagtt tgtgcgcaac gttcccaacc ttctctggat ttttactatc tttttggtgt
    23821 tcaaaatgaa atccacacca gcaggtatta cagcctttac tctctttaca tcagcagcct
    23881 tggctgagat tattcgaggc ggtctcaatg ccgtagacaa gggacaatac gaagcaggaa
    23941 tgtcacaagg cttcacctca gcccaaatcc tctactacat cattctccca caagccatcc
    24001 gcaaaatgct accagccatc atttctcagt ttgttaccgt gattaaggat accagtctcc
    24061 tctactctgt tatcgcccta caagaactct ttggagccag ccaaattctc atgagccgtt
    24121 atttcgaacc agagcaggtc ttcagtcttt acatcctgat tgccctcatc tacttcagct
    24181 ttaacctagc aatttctagc ctgtctcata tgctagccaa acgttggcaa caagccgcag
    24241 aataatactc ttcgaaaatc tcttcaaacc acgtcagctt caccttgccg tatatatgtt
    24301 actgacttcg tcagttctat ccacaacctc aaaacggtgt tttgagcagc ctgcgggcta
    24361 gcttcctagt ttgctctttg attttcattg agtataaaca gccactctcc aattcaattg
    24421 gagagttttt tgatgagagt agatatttat agacctcaat ttgacaccat acattttcta
    24481 tgataaaatg taacaaattc atttacaaca aatcgaaatc taaatgaaat ggaattttct
    24541 atgaaatcag tcaaaggact actctttatc atagctagtt ttatcttgac tcttttgact
    24601 tggatgaaca cttctcccca attcatgatt ccaggactag ctttaacaag cctatctctg
    24661 acttttatcc tagccactcg tctcccacta ctagaaagct ggtttcacgg tttggagaag
    24721 gtctacaccg tccacaaatt cacagccttt ctctccatca tcctactaat ctttcataac
    24781 tttagtatgg gcggtttgtg gggctctcgc ttagctgctc agtttggcaa tcttgccatc
    24841 tatatctttg ccagcatcat ccttgtcgcc tatttaggca aatacatcca atacgaagct
    24901 tggcgatgga ttcaccgctt ggtttaccta gcctatattt taggactctt tcacatctac
    24961 atgataatgg gcaatcgtct ccttacattt aatcttctaa gttttcttgt tggtagctat
    25021 gcccttttag gcttactagc tggtttttat atcatttttc tatatcaaaa gatttccttc
    25081 ccctatctag ggaaaattac ccatctcaaa cgcttaaatc acgatactag agaaattcaa
    25141 atccatctta gcagaccttt caactatcaa tcaggacaat ttgcctttct aaagattttc
    25201 caagaaggct ttgaaagtgc tccgcatccc ttttctatct caggaggtca tggtcaaact
    25261 ctttacttta ctgttaaaaa ttcaggcgac cataccaata atatctatga taatcttcaa
    25321 gccggcagca aagtaaccct agacagagct tacggacaca tgatcataga agaaggacga
    25381 gaaaatcagg tttggattgc tggaggtatt gggatcaccc ccttcatctc ttacatccgt
    25441 gaacatccta ttttagataa acaggttcac ttctactata gcttccgtgg agatgaaaat
    25501 gcagtctacc tagatttact ccgtaactat gctcagaaaa atcctaattt tgaactccat
    25561 ctaatcgaca gtacgaaaga cggctatctt aattttgaac aaaaagaagt gcccgaacat
    25621 gcaaccgtct atatgtgtgg tcctatttct atgatgaagg cacttgccaa acagattaag
    25681 aaacaaaatc caaaaacaga gcttatttac gaaggattca agttcaaata agtaatcata
    25741 ctctcctggg atttcccagg agagtttttt atagccaaat gaaataagac cggaacgatg
    25801 gaattttggc attcaaatca attgataaga atattttata gtggagtgaa ataggatacg
    25861 aacaaattga ttaggaaaat caaatgaatt tatagaaatc ttttagcagt tatgttgtcc
    25921 tattctagtt tcaaaacgct atagaagcag cattgtacta gtctagattc agtttactat
    25981 actaaaacga gtagcttgaa atcaaaaaac ccaccctcac aggcaggttt tatctgtatt
    26041 attcagctag attatgcttt accttctgaa ccgaatacgt cgatacgttc ttcaaccgat
    26101 gcttggatag cttttacacc gtcagccaag aatttacgtg ggtcgaagag ttttttcttg
    26161 tcgtattctg cttcgtttgc ttcgtagtca cgagcaaatt tacgagttgc gttagcgaat
    26221 gcgatttggc attctgtgtt aacgttaact ttggcaacac caagtttgat agctgcttgg
    26281 atttgctcat caggaatacc tgatccaccg tgcaatacga ttgggaatcc tggaagagct
    26341 tctgtcaatt tttgcaagtg gtcaaggtca agaccttccc agtttactgg gtaagggccg
    26401 tggatgttac cgataccagc tgccaagaag tcgataccag tttcaaccat tgctttagcg
    26461 tcttcgattg gagccaattc acctttaccg atgattccgt cttcttcacc accgatagta
    26521 ccaacttcag cttctactga gataccttta gcgtgtgctt tttcaacaac ttctttagcc
    26581 aatttaaggt tttcttcaac tggaaggtgt gaaccgtcaa acatgattga agtataacca
    26641 acttcgatac actcaagtgc atcttcgtag tgaccgtggt caaggtggat agctactggt
    26701 acagtgatac ccattgattc aacaaggtta gcgatcaagt tgcgagcaac tttgtaacca
    26761 cccatgtatt tagcagcacc cattgaagtt tggatcaaaa ctggagcttt tttagcttct
    26821 gctgcgcgca agatagcttg agtccactca aggttgtttg tgttaaatcc accaactgca
    26881 taaccgttgt cacgggctgc ttggacaaat ttttctgctg aaacgattgc cattttatca
    26941 ggcctcctgt atatttttat gggtcatccc atttacattg ttcattttat cactttttgc
    27001 caaaaaaatc tagtttttcc cgcagtttcg attgattttc ttctaactcc atctatgtaa
    27061 accctttctc tccctagtct tgggcgactt ttggaaaagc tataaagaag gttaaacgat
    27121 tctcctccat ctcgaaacga taagctaatt tttcatgttc taatagactc ttaaccacaa
    27181 agagccccat accagacccc ttgaccttgc gactggcatt gtcagaaaaa gactgggcta
    27241 gtttttcttg ttcctctgag ctacagctat tttcgataaa aagttctcct tctctttctc
    27301 caattcgaac taagccacct ggaacagagt gcttaatggc attgctgatg agattagaaa
    27361 gaatcaactt cataactgat gggtttagat aagcctgctg atgggtcaaa ctattgtcta
    27421 tctggagctc tctttccttg gctagcaagg cataatcttt gaccagattt tgcgtcatct
    27481 ggaggaggtc aattgtttcc ctatcatctc gcaattcctg cacagaagag agggaaagta
    27541 tctgcagaac atggtgattg agttcatcca caatccccaa ggcaactccc agatactggt
    27601 ctctatcctt ataacgaccg atattctctc tcatattttc gattaggatt ttcaaactag
    27661 ccagcggtgt tttcaattca tgagaagctc ctcgtaggaa ttcgaccttc atcttctcca
    27721 gctggagaat ggcttcattc ttttcatgca agtccgcaat aacagtcaag agatgctggt
    27781 agaggctatt gatttgttcc ttgagattac ctatctcatc cttagaatcc acgcgcaatc
    27841 gcacttggga atccaggtcc atcatccgac gggtcacccg cttgatttcc aaaatcggtg
    27901 caacaatagt ccgggcgtag atgtaggcca ccaagaggga aatcagaaag gaggccagca
    27961 aggtataggg aagaaactgg agactgattt gctccgcttc cttttgtaaa tccatggaag
    28021 ctagaaactg gagaatcata gtaccaccgt cttgcgtttt cacctcgcgc tcctcaataa
    28081 agagagaggt tgtctggcgg tctgtgtcca gaggaagact gtccttgact tctaacttgt
    28141 cctcggtcat ctcacctttg acggtcccct tgatatcact agtctgggaa tacaagtcta
    28201 acacttgctc gatactctgc ctatctttcc cttctaggga ctgggcaatg gctgttgcct
    28261 tttgaccaat ggtttcctga cgatgactca gataagtcga aggaaaaaga aaataaatag
    28321 ctaaatgaag gcagataacc agaacactaa atatcgagaa ggtatagata aatatctttg
    28381 caaataaacc tgttcgtttc attttcgctc caatttataa ccaacattgc gcacagtgag
    28441 gatacaatcc aagtctagct ttttccgcaa ttccttgata taaacatcaa taacacggtc
    28501 aaagggaacc tcatctgtcg ctttccagac ggcatcgata atctgagacc gagtcaaggc
    28561 ccggccttca tttttcacta gatagtccag aatttccaac tctttggcat tgataggcac
    28621 ttcttgacct gcgaggcttg cactgtagct ttcaaagtcc accttggtat ccttgtaaga
    28681 aaagattcgt cctgtatcgt agtagcgctt gaaaatcgcg tccaccctca cttttaagag
    28741 ggagagagag aaaggttttt ccagatagcc atctgccaaa gaggcaaagg cactcatctt
    28801 gtattcctca tcctgaaaag ctgtcaacat caagacagga acctgactgg ttttacgaat
    28861 ctcagctagg acttctaagc cgttaagctt gggcatctgg atatccagta aaaccagggc
    28921 cacctcatag ctagaaaatt gctccagagc ttcctgaccg tccgctgcct caatagtttc
    28981 atagccacaa tccgtcaaat aatcactgac cccctcacgg atcatctctt catcttctac
    29041 aattaaaatt ttcatacttt aactgctctc tattttttat ttttcttaga ataaatacct
    29101 actctatttt ctattatagt ctcttgctgg ccttttgtct gtaagcaact gatcactaga
    29161 taaaacgttg tgaaattcct ttctcataaa ttccataact ttagtatatt atatttaagc
    29221 actaaagtac aaagaaagca actgaaagca atgattttca ccactgcttt cagatttatt
    29281 ttgaattgtt aaatagctat tcctatccac tattcttgaa tagaaacaca agatgcaatc
    29341 tttattccag actcattttt tcaaatttat tcaccatcca gcaagagctc ttttggttgt
    29401 tttctaagga gattgcttga agcaagcgcc ataacgagaa ccactagaac caaggcaagg
    29461 acaaaaatga tgataaagtc tgatgtctga atggaaatgt ctaggctcga caaggtcttg
    29521 ctaaagccat ctacttctgc accgccacca aggttagagg cttgagccgc cttactagcc
    29581 tgtttggcaa cacctgaagt cacattggca aggacagtgt ttccaattgc acgggcagtg
    29641 taattagcta ggaagtaagc agaaactaga gcagggatag caatcaagat agattcggtg
    29701 atgaattgac ccaagatact tgcctgcttg aggccgatag agaggagaat tcccacttcc
    29761 ttgcgacggg cgttgatcca aaggctgagc aagagggcaa ggaggagaac tgagaagctc
    29821 aagctacccc agaagaggag gttggccatc ttgtacatac cagagataga ttgctcaaga
    29881 gctgggtagt tagaggagct cttgacgagt gtgtagctct tccagttgat accactgatg
    29941 ccattcaact ctttcataac atcatccaag ttcttgtctg ctgttacaaa gaaggttgcg
    30001 tccccataaa tggctgtgtc ttctgtgtat ccataaagtt ttgcagcagt gtgaatgtct
    30061 gtaatagctg tgttttcgta aagttcttgt gagtaggtta ctgctgactt attatgacca
    30121 tcaaagagtc ccttgattgt cacttcaact gtttccttgg ctcctttttc attatctgca
    30181 tcgtagatat tagagtccag tttaaccttg tcccctactt tccagccgtg tttggctgcc
    30241 aagtccttgt gcaagaggat tttatccttg tcgtcgttgg ttaagtgctc tccttcgact
    30301 agtttataag aaccagagac aaacttgtct tctttagagg agtcattgac acctgtaatc
    30361 atcaagctac ttccaaaacg tttggcacga tcagcagtga gattcttctt ggtttctggc
    30421 gtttcaatca ggtcatatcc agtcaaatct ccgatagcgt tgatacgttt gacataagac
    30481 tcaatggcct tgttttcggt gatttttttg atgtcttcac ccttgatatt cccagcaccg
    30541 cgaggcgttc cttggttgac gcgacgattg atttgcatgg agaagctatt ggtgatattt
    30601 ttaaaggtct cctgagaagc cttggcagta gctcccttga ttgacaagcc gaccaaactc
    30661 aagctcgcca tgaggagaat aatcaggaag atgacaatcg atttgaaaaa cttccttgta
    30721 acataggcaa atgcgttgtg taacatagat tccctttcta gattttgttt taatcattct
    30781 attaaagtaa gctcaaatta tttactagta ttgcgcgttt cagtcagttt cttatccttt
    30841 aattcaagtg taatatctga cgcttgtgcc acttctttac tgtgagttac gacaatcaca
    30901 catttacctg ttttctgggc aagtgatttg agtagttcga caatatctcc agcagtttta
    30961 ggatccagat ttcctgttgg ctcatcagct agaataactg gagcttctga gaccaaactg
    31021 cgagcaatgg caacacgttg ctgttgacca cctgataact ggagaacatt ccgcttgatc
    31081 tggctttcat ccaaaccaag ctcaagaagt gtattcttgc ttgccttttt gttgaccaat
    31141 cggatatttt ccagcggaga aagataatct atcaagttat aattttgaaa gaccagggaa
    31201 atatggtgca tgcgatggta agaatagccc ttcttacgaa tatcctctcc ttgaaaaagg
    31261 atagaacctt caacaggact atctagacca gcaagtaggg acaagagtgt ggattttcct
    31321 gctcctgact ccccaataat actgtaaaat tttccgggtt caaaattata attgatctga
    31381 tataggactg cttcagcagt attcttataa cggtaggtaa catcttgtaa ttgtaataaa
    31441 gtcatgattt ctccttctta actaatagat gataaaattt ctttcggtga ttttctaaat
    31501 aagaatagga aacaaagggc tacagataag caactaagca gaactagaaa aacataggat
    31561 tctgcaaaag ataagatgct agttgataaa ctgcttgctt tggctagtgt atcttgtaag
    31621 cttgcctgat ctccacttgc tagtagagtt tggagtaggt aagttgtgat tccgtttcct
    31681 gcaacaaatg ctggaagcaa agctccaaga gataccaaaa ctacctctaa acagaattgt
    31741 aggaaaatcg agctcttgcc ttttccaagt gcaagtaaaa tccccacttc atagacccgt
    31801 tctctcaacc agagagacaa aaccagaatt aaggctccag ctcctgctat caacatccca
    31861 taaaggaaga tggtcaggaa ggtttggaaa gttgcaactg agtctttgat ttgttcaaaa
    31921 gccttgtttt ccttttcgac ttggtagcct tgattttcca aggccaagtt ttctacctgc
    31981 ttcatgagtc cgtccatttc cttaggattt tctacataga agcgtgctgc actgacttga
    32041 gcttcactat tgcccaaaag ggtttggcta ctttcatagt ctgtaaagac ttgattttca
    32101 ctgaagtcag aagacaagcc tgtgaatttc tcttgttttt taccagaaaa gatgccgata
    32161 atctcaaact ctactgtttg tccttttcca gattcagact gaccagcatc caagccaatc
    32221 ttgtcatgaa gtgaaagacc gttcttctta gccaattctt cgtggataag gattttcttg
    32281 gaattccctt tttgaaggtg tcgcccttct tttagattga aagccgaact ggtaaaggtt
    32341 acatccttgg atgaatcctc aagagccgtt aagctaacca agttattgtc tgcagctgat
    32401 aaatcatcac gctccacgct ctgctcgcca gtcactgctt ccttgtcttt tagttttgcg
    32461 accgtctcga gttcaggaga gacattttcc agccccttaa tcttgcttac agatgctagg
    32521 tctgacaact tgaatgtctg accattctct atcttcttaa tagaaaaaga tgtattgagt
    32581 gatttataaa gattgctttc tactgttttg ttggacttca tcagagtcaa acaggctgaa
    32641 attccggcca ataagaccaa taaaatcaga aataaaataa aacttctcag tcgctttctg
    32701 ctgacataag cccaagatct ttggattgga ttcatttgtc acctccatat ttgtaagact
    32761 attataaaac ccaaatatga aatgtttatg aaatacgaaa aaaaaatatc gagtagggga
    32821 taatctctag cccctctcat accaccgtac gtgccgttcg gcatacggcg gttcaactaa
    32881 cttttaacgc atgtcgttca aggtaataat ccaaacacga aaccagtcca cgtttttcaa
    32941 ggactggttt tgatatagca cgtttaagta ccgacttctg agctactata gtagattgaa
    33001 actagaatag tacacctcta cttctaaaat attgttagaa atcgatttga ctgtcctgat
    33061 tgattcgtcc tactcttatt tcattttact ataattgata gtggtcgccc cagccagata
    33121 ccttatctgc tatccattta ggaaccccta acttaagcaa tccccataat cgtctcgatt
    33181 tcttcttcca ttgcttccag ataatcactc gtaggcgagt acgcaagcgc tcatctatgc
    33241 tagtgactat acttttcata tttataattc attcctttcg tttcactcaa ggcacaacac
    33301 agaatgaaaa agtgttgtgc tctttatttt gttttataat aatagttaga aagcctatca
    33361 ctactacaaa tcacggggag gtgaataagt gagtggtaca gccactacct cgcatatttt
    33421 gtcacatcat ttaacggtac ataataagtt gtaccatctg aataagttgc tacaatatca
    33481 tttgcatgct ctccttcacc tttagcaaag gttggagctc ctactggata atttttattt
    33541 gcctctttca atttttcaat aatggcattt ttttctgtat cttttatatt atcaggattt
    33601 ttcactaaga ttttgtctgg atatgtcggt ttagcagaaa caatttttac tgttatttct
    33661 tttttattcg aagcacttgt ccagtttcca gcattatctt tagcatttaa ttttacagta
    33721 attcctgaac taagaacttc agtagcaggt tgattatcaa cattattcaa ctttaatttc
    33781 aaaagagctg ttgcatcaga cgttttatca atcgttgtat ataatgataa attgttatta
    33841 taaccagttt cttcatattt agctgtttgt gagctacttg aaacagaact gaaattatgc
    33901 ccactacctc cctgattatc ttcaatgctt acgtctaaat gaacttcccc actattattt
    33961 ggcttagcaa caactgttat agtaaaataa cataaaattt gcataaatag attagggaaa
    34021 tcaaagcaac ttctaggaat gttttatact cttcgaaaat caaattcaaa ccacgtcagc
    34081 ttcaccttga cgtactcaag tacagcctgc ggctagcttc ctagtttgca ctttgatttt
    34141 cattgagtat tagcagtcac agtgtacttt cccagcatca agtcactata actctgcaca
    34201 taaaaatgga gaagatggcc atcctcttct ccaaatatta a
//
LOCUS       DBEJJV010000025        32437 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.025, whole genome shotgun sequence.
ACCESSION   DBEJJV010000025 DBEJJV010000000
VERSION     DBEJJV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 32437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.025"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..2788
                     /locus_tag="ACL3GT_001303"
     CDS             <1..2788
                     /locus_tag="ACL3GT_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0516969.1"
                     /translation="NQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGED
                     GKTPEVTVTPGKDGHSTDITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGQNGN
                     PPHTIVTFYTDENNDGKYTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVY
                     QEDPANPGQPLNPEKPLAVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTT
                     VFVQDGAKGETGATGQDGQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKD
                     GRAPKIKVEDITSPSRIRRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKD
                     IYNGIDGRDGSAPTITTKDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENP
                     DGSHTITVTNPDGSTKETVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIK
                     DGKDGKAATATTTENPDGSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDG
                     SHTIVITNPEGVTTETTVRDGKSPKVTITDEQNGTHKISVLNGDGTTTETIIKDGKSP
                     VATVRDNQDGTYTIRVENGNGTVSETTVRDGKSPTAKVVDNGDGTHTITVVNSDGTTT
                     TTTVRDGREPKLEVIDNNDGSHTIKVTGADGKGTTTTIFDGKSPKANIVDNGDGTHTL
                     TIVDSDGREYKSIIKDGKDGKDSVSPTVTVKNNNDGTHVVTITNPDGSKTEMVIKDGK
                     DGKSPKVSVEDNGDGSHTITIINSDGTVTKTVIKDGKDGRDGRDGRDGKDGKDGKDGK
                     CGCQDKPVTPSNDKPVPPTPNVPTPEVPVKPVPAQPTPNVPTPEVPVQPTPAVPTPEV
                     PVKPVPAVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQSDYISVLLGS
                     GILLSLYVGRRKED"
     gene            complement(3025..3573)
                     /locus_tag="ACL3GT_001304"
     CDS             complement(3025..3573)
                     /locus_tag="ACL3GT_001304"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HGR0516970.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            3894..4382
                     /locus_tag="ACL3GT_001305"
     CDS             3894..4382
                     /locus_tag="ACL3GT_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HGR0516971.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            4379..5566
                     /locus_tag="ACL3GT_001306"
     CDS             4379..5566
                     /locus_tag="ACL3GT_001306"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0516972.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            5559..5924
                     /locus_tag="ACL3GT_001307"
     CDS             5559..5924
                     /locus_tag="ACL3GT_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0516973.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            5940..7286
                     /gene="asnS"
                     /locus_tag="ACL3GT_001308"
     CDS             5940..7286
                     /gene="asnS"
                     /locus_tag="ACL3GT_001308"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HGR0516974.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            7439..7729
                     /gene="rpsF"
                     /locus_tag="ACL3GT_001309"
     CDS             7439..7729
                     /gene="rpsF"
                     /locus_tag="ACL3GT_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HGR0516975.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            7741..8211
                     /gene="ssbA"
                     /locus_tag="ACL3GT_001310"
     CDS             7741..8211
                     /gene="ssbA"
                     /locus_tag="ACL3GT_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HGR0516976.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            8243..8482
                     /gene="rpsR"
                     /locus_tag="ACL3GT_001311"
     CDS             8243..8482
                     /gene="rpsR"
                     /locus_tag="ACL3GT_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HGR0516977.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            8777..10177
                     /locus_tag="ACL3GT_001312"
     CDS             8777..10177
                     /locus_tag="ACL3GT_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HGR0516978.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            10179..10538
                     /locus_tag="ACL3GT_001313"
     CDS             10179..10538
                     /locus_tag="ACL3GT_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HGR0516979.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            10592..11341
                     /locus_tag="ACL3GT_001314"
     CDS             10592..11341
                     /locus_tag="ACL3GT_001314"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HGR0516980.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVNPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            11331..11630
                     /locus_tag="ACL3GT_001315"
     CDS             11331..11630
                     /locus_tag="ACL3GT_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HGR0516981.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            11701..12636
                     /locus_tag="ACL3GT_001316"
     CDS             11701..12636
                     /locus_tag="ACL3GT_001316"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HGR0516982.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            12722..13234
                     /locus_tag="ACL3GT_001317"
     CDS             12722..13234
                     /locus_tag="ACL3GT_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="HGR0516983.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAPGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            13218..13867
                     /locus_tag="ACL3GT_001318"
                     /pseudo
     CDS             13218..13867
                     /locus_tag="ACL3GT_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614493.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            13968..14165
                     /locus_tag="ACL3GT_001319"
     CDS             13968..14165
                     /locus_tag="ACL3GT_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0516984.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(14208..15653)
                     /locus_tag="ACL3GT_001320"
     CDS             complement(14208..15653)
                     /locus_tag="ACL3GT_001320"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HGR0516985.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQSYLVRRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVKDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            15759..17381
                     /locus_tag="ACL3GT_001321"
     CDS             15759..17381
                     /locus_tag="ACL3GT_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HGR0516986.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLCSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            17585..19543
                     /locus_tag="ACL3GT_001322"
     CDS             17585..19543
                     /locus_tag="ACL3GT_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0516987.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSVQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            19715..19948
                     /locus_tag="ACL3GT_001323"
     CDS             19715..19948
                     /locus_tag="ACL3GT_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HGR0516988.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            19966..20487
                     /locus_tag="ACL3GT_001324"
                     /pseudo
     CDS             19966..20487
                     /locus_tag="ACL3GT_001324"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
     gene            20674..21396
                     /locus_tag="ACL3GT_001325"
     CDS             20674..21396
                     /locus_tag="ACL3GT_001325"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0516989.1"
                     /translation="MNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPSGSGKSTIV
                     RLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRL
                     VTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRLLSGGRSQRLQIARAYLKDAEIL
                     IFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSG
                     THKELLENHERYARFVQEQMIE"
     gene            21554..22648
                     /locus_tag="ACL3GT_001326"
     CDS             21554..22648
                     /locus_tag="ACL3GT_001326"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0516990.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            22656..23822
                     /locus_tag="ACL3GT_001327"
     CDS             22656..23822
                     /locus_tag="ACL3GT_001327"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HGR0516991.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKC"
     gene            23915..27013
                     /locus_tag="ACL3GT_001328"
     CDS             23915..27013
                     /locus_tag="ACL3GT_001328"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0516992.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVDRQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAIQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            27061..27678
                     /locus_tag="ACL3GT_001329"
     CDS             27061..27678
                     /locus_tag="ACL3GT_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HGR0516993.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            27689..29023
                     /gene="murC"
                     /locus_tag="ACL3GT_001330"
     CDS             27689..29023
                     /gene="murC"
                     /locus_tag="ACL3GT_001330"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HGR0516994.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLYQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            29033..29497
                     /locus_tag="ACL3GT_001331"
     CDS             29033..29497
                     /locus_tag="ACL3GT_001331"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0516995.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            29494..29988
                     /locus_tag="ACL3GT_001332"
     CDS             29494..29988
                     /locus_tag="ACL3GT_001332"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0516996.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            30069..31724
                     /gene="mltG"
                     /locus_tag="ACL3GT_001333"
     CDS             30069..31724
                     /gene="mltG"
                     /locus_tag="ACL3GT_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HGR0516997.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAETF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            31795..32277
                     /gene="greA"
                     /locus_tag="ACL3GT_001334"
     CDS             31795..32277
                     /gene="greA"
                     /locus_tag="ACL3GT_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HGR0516998.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT         9950 a         6052 c         7275 g         9160 t
ORIGIN      
        1 aaatcaaggt aaagacggtg ataaatacgt caatacagaa acaggcgacg tcttcgttaa
       61 gaataacggc aactgggata aagagggcaa catcaaggga cctaaagggg acaaaggtga
      121 acgcggagaa gatggtaaga ctccagaagt aactgtaact ccaggtaaag atggccatag
      181 tactgacatt acattcactg ttccaggtaa agatccagtt acagtaaatg ttaaggacgg
      241 agaaaatggt ctgaacggta aaactccaaa agttgattta cttcgtgtcc aaggacaaaa
      301 cggaaatcca cctcatacaa ttgtgacatt ctatacagat gaaaacaatg atggcaaata
      361 tacaccagga actgatgaac ttctaggttc agaaatgatt aaagatggtg ctaaaggtgc
      421 ggacggacga gatggtaaat cattgcttac tgtcaaggat ggtaaagaaa ctaaagttta
      481 ccaagaagat ccagctaacc caggacaacc attaaatcca gaaaaaccac ttgcggtaat
      541 tagagatgga gtagatggaa aatcacctac agttacagct gttcgtaaag atgaagcagg
      601 gcataaaggt gtagaaatca ctgttgataa ccatgatggt tcacaaccaa ctacagtctt
      661 tgttcaagat ggtgctaagg gagaaactgg tgcaaccggt caagatggac aaactcctac
      721 aatcactact caacgtggac aagatggcca aagcactgtt gtaactatca caacatcagg
      781 taaagatcca gtaaccttca ctgtaaaaga tggtaagaat ggtaaagatg gccgtgcacc
      841 gaaaatcaaa gtagaagata ttacttcacc ttcaagaatt agacgcgata cagatgctgc
      901 tgcaactcca acgcgtaacg gtatccgtgt tacagtttat gatgatgtta atgacaatgg
      961 ggtatacgac gaaggtgtcg ataaagtatt aaatagtaaa gatatttata acggtataga
     1021 tggacgtgat ggttcagctc caactattac tacaaaagat aatggagatg gaactcacac
     1081 tatcacagtt caaaacccag atggttctga atcaacaaca gttgttaaag atggtaaaga
     1141 cggtaaaact gcgaatatca ctacaacaga aaacccagat ggaagccaca caattacggt
     1201 gacaaatcca gatggttcaa ctaaagaaac tgttgttaaa aacggtaaag acggtaagac
     1261 tcctaaagtt gaagtaacgg ataacaacga tggaactcat actgttaaag ttacagatgg
     1321 agacggcaat gttaccaacg ctatcatcaa agatggtaaa gacggtaaag ctgcaacagc
     1381 aacaactact gaaaatccag atggaagcca cacagtaaca atcactaacc cagacggaac
     1441 taagaatgag tttgttgtta agaatggacg tgacggtgtt gacggacgta ctccaaccgc
     1501 atctgttcgt gataatggag acggaagtca tacaatcgtt attacaaatc cagaaggtgt
     1561 gacaactgaa accacagttc gtgatggtaa atcaccaaaa gtgactataa ctgatgaaca
     1621 aaatggaact cataagatct ctgttctaaa tggtgacgga acaactactg aaacaatcat
     1681 taaagatggt aaatcaccag tagcaacagt tagagataac caagatggta cttacactat
     1741 tcgtgtggaa aacggtaatg gtactgtttc tgaaaccaca gttcgtgacg gtaaatcacc
     1801 aactgctaag gttgtggata atggagatgg aactcacact atcacagttg tgaactcaga
     1861 cggaacaact acaacaacta cagttcgtga tggtagagaa ccaaaacttg aagttattga
     1921 taacaacgat ggttcacaca ctattaaagt gacaggtgct gatggtaaag gaacgacaac
     1981 tacaatcttt gatggtaaat caccaaaagc gaacatcgtt gataacggag atggaactca
     2041 tacattaaca atcgtagatt ctgatggtcg tgaatacaaa tctattatca aagatggtaa
     2101 agacggcaaa gatagcgttt caccaactgt aactgttaaa aataataacg atggaactca
     2161 cgttgttaca atcactaatc cagatggaag taagacagaa atggtgatta aagacggtaa
     2221 agatggtaaa tcaccaaaag tttctgttga agataatggt gatggtagtc atacaatcac
     2281 aatcatcaat tctgatggaa ctgtgacaaa aacagttatt aaagatggca aagatggtag
     2341 agatggacgt gatggtcgag acggcaaaga cggtaaagac ggtaaagatg gaaaatgtgg
     2401 atgccaagac aaaccagtaa caccatcaaa tgacaaacca gttcctccaa caccaaatgt
     2461 gccgacacca gaagtaccgg ttaaacctgt gccagcgcaa ccaacaccaa atgtaccgac
     2521 accagaagtg ccagtacaac caactccagc tgttccaaca ccagaagtac cggttaaacc
     2581 agtaccagcg gttccagaac aaccagtagt accaacaccg gctcaaccag caactccagt
     2641 aaatgctaat ccagtagcac caactacagg taaagaaaac cgtggggaca aattacctga
     2701 aactggaagc caatctgatt atatctctgt tcttttaggt agcggtattc tattgagcct
     2761 atatgtagga cgaagaaaag aagattaatc agccaaaagc agtcactaat ttctcgaaag
     2821 aagatgataa gtgatagatc tcgaatgaaa gaatattctt agaatgattt tcctatgatg
     2881 gaaaagactg ctaaaaacct tgagtggtaa cgctcaaggt ttttttggat ggctgatgtt
     2941 tgtctgaaaa tcttgattga gaaataaaaa gccaccctat taggtggcta taattgattt
     3001 agactttcta aaattttcta ttttttactg aatcgcttcg accaagtctt gagcttgttt
     3061 ttcaagtgag tttaggactg tttcttcaag aaccaatttt ccgtctgccc aggcagagtc
     3121 attaacacgt gcagcagtga aatcaccaac gccttgtgta cggataaatg gcaagaggtc
     3181 tttgtagata gcgaaaagtt gatcgtgccc tgcattggct acagatgata ctgtgacaaa
     3241 cttgtcttga agggcagaaa cgccacgtgt atcagacaag tcaagggcac gagatagcca
     3301 gtcaagcaag tttttcactg taccagggat agagaagttg tagactggag agaaaatcca
     3361 gatagcatcc gcaacgagaa ctgcttcacg agcagcagct acagctggat gtgttggaac
     3421 ttccaaatct tggctgaaga gaggaagggc tgaataatca aggtagctaa cttccgcttt
     3481 accagcaagt gctttctcag cttcgagcgc catttggtgg ttgaaagaac cttgacgtag
     3541 tgatccgacg ataaataata cttttttaga catgatgtgt ctcctttttc ttaaaatttc
     3601 gagaactctc tcgttgttat aaaatatatt acaacaaaac aaaagaactt gcaagaaatt
     3661 tgctcagagt ttatttgaaa attgtaaaat ttcggaaact ctaatcattt gtgactgaaa
     3721 aagtaagaac tgtttcactt tcaaaatcgg ttttgtttga agggagaaat agaattggtt
     3781 gctcaaagca cagctttgag gttgcagata aagctgacgt ggtttgaaga gattttcgaa
     3841 gagtattctt atattcactt gtaataaagc ttaatagatg gtaaaataga cgagtgaaaa
     3901 aaagacaaaa caaagcaaaa aataatctac tgtggcagta tggtctaggg atgacgattt
     3961 tgtttgtggt tatcagtggt tcctttctgt atatggtttc tcttagcatg aaaccctatc
     4021 aaacagctaa aagtgaagga gaaaaattag ctcagcagta tgcaggatta gagcaggtcg
     4081 atcaggttga tttatacaat ggcttggaat cttattacag cgttcttggt cgtaataaac
     4141 agcaagaagc gcttgctgtc ctgattggta aagatgacca taagatttac gtttatcagc
     4201 taaatcaggg tgtttcacaa gaaaaagcag aaacggtttc taaggaaaag ggagctggcg
     4261 agattgacaa gataaccttt ggccgttatc aagataagcc aatctgggaa gttaagtcag
     4321 gatctgattt ttatctagta gattttgaaa caggagcatt ggtcaacaag gagggcctat
     4381 gaaactatcc aaccgtgttt tagaaatgga agaaagtgtg actttggctg ctggagcccg
     4441 tgccaaagca ctgaaggctg agggtagaga tattttgtct ctaaccttgg gtgagccaga
     4501 tttcactact cccaaaaata tccaagatgc cgccattgca tcgattcgag atgggcgtgc
     4561 ttctttttat acagtaacct caggtctgcc agagcttaag gcggcggtca atagctactt
     4621 tgagcgcttt tacggctatt ctgtagcgtc aaatcaagtg acagtcgctg cgggagccaa
     4681 atattctctc tataccttct ttatggctgt ggtcaatcca ggtgatgaag tcatcatccc
     4741 aaccccatac tgggttagct atggagatca ggtcaagatg gcagaaggcg ttcccgtctt
     4801 tgtttctact aaggaagaca atcactttaa ggtgaccgta gatcagttag aagcagctcg
     4861 cactgacaag accaaggttt tggtgctgaa ttcgccatct aatcccacag gtatgattta
     4921 cacccgtgag gaactcttgg caattggaaa ctgggctgta gaaaatgata ttctcatcct
     4981 agcagatgat atctatggcc gcttggttta taatggtcat gagttcacac cgatttctag
     5041 cctatcggaa gcgattcgca agcaaacagt ggtcatcaat ggtgtgtcta aaacctatgc
     5101 catgactggt tggcggattg gttatgccgt tggagaagca gatattatcg ctgccatgtc
     5161 caagattgca ggtcaaacaa cttcgaatcc gtcagcagta gcccaatatg cagcagttga
     5221 ggctctatca ggtgagcaag atactgtaga aagcatgcgt caggcctttg aggaacgtct
     5281 taataccatc tatcccctcc ttgcagaggt accaggattt gaagtggtca aaccgcaagg
     5341 ggccttctat ctcttcccaa atgtcaaaaa ggccatggag atgaaaggct acacggatgt
     5401 gacagacttt acaactgcta tcttagaaga agccgaagtg gccttggtaa caggagctgg
     5461 atttggagca ccagaaaatg tccgcctcag ctatgcgaca gacctagaca cgcttaaaga
     5521 agcagtcgaa cgcttgaaag catttatggg tagtgagaat gattgatcat tttgagatta
     5581 aggtaaagga tttacaaatt tcagaaggat tttataggag ttttctcgct cctttggact
     5641 ataaattggc ttttaagact agttctctaa ttagttttct atccccgaac agccctcatc
     5701 ctggtggtga tttttggctg actcagggaa cacaagatcc tgttcatttt gcttttttag
     5761 cagaaaataa ggaagaagtt caggcttgtt atgaggctgg cttagaggca ggtgggcgag
     5821 acaatggggc tcctggttat cgaagtgagc atccgattta ctatgctgct tttatgattg
     5881 acctggatgg gaacaatata gaggtggttt gccataaaga ataaaaaaga aaaggaaaaa
     5941 taatgacaaa acgtgtaacg attattgacg taaaagacta tgttggtcag gaagtgacga
     6001 ttggcgcttg ggttgccaac aaatcaggaa aaggaaaaat cgctttctta caattgcgtg
     6061 atggaacagc cttctttcaa ggtgtggctt ttaaaccaaa ctttgtcgaa aaatttggtg
     6121 aagaagtggg acttgagaag tttgatgtta tcaaacgctt gagccaagaa acgtctgttt
     6181 atgtgacagg tattgtcaaa gaggacgaac gttctaaatt tggctatgag ttggacatca
     6241 cagacatcga agtgatcggt gaatctcaag actacccaat cacaccaaaa gaacacggaa
     6301 cagacttttt gatggataac cgtcacttgt ggctacgctc tcgtaagcaa gtagctgtgt
     6361 tgcaaatccg taacgctatt atctatgcaa cttatgagtt ctttgacaag aacggtttta
     6421 tgaagtttga cagcccaatt ctttcaggaa atgcggcaga agattctaca gaactctttg
     6481 aaactgacta cttcggaacg ccagcctact tgagccaatc aggtcagctt tacctagaag
     6541 caggggctat ggctcttggt cgtgtctttg actttggtcc agttttccgt gctgaaaaat
     6601 caaaaacacg ccgtcacttg actgagttct ggatgatgga tgctgagtac tcatacttga
     6661 cacatgatga gtcgcttgac ttgcaagaag cttatgtgaa agctcttcta caaggtgttc
     6721 ttgaccgcgc gcctcaagcc ttggaaacct tggaacgtga tacagaactc ttgaaacgct
     6781 acattgcaga gccattcaaa cgtatcactt acgatcaagc cattgacctc ttgcaagagc
     6841 atgaaaatga tgaagatgct gactacgagc atcttgagca tggtgatgac tttgggtcac
     6901 cacacgaaac ttggatttca aaccactttg gtgtgccaac atttgtcatg aactatccag
     6961 cagccatcaa ggccttctac atgaaaccag ttcctggaaa tccagagcgc gtgctttgtg
     7021 cagacttgct tgctccagaa ggctatggag aaattatcgg tgggtctatg cgtgaggaag
     7081 attacgatgc ccttgtcgct aagatggatg aacttggcat ggatcgtaca gaatatgaat
     7141 tctaccttga ccttcgtaaa tacggtacag ttccacacgg aggatttggt atcggtatcg
     7201 aacgtatggt aaccttcgca gcaggaacaa aacatatccg tgaagctatt ccattcccac
     7261 gtatgttgca ccgtatcaaa ccataagaac aggaaaacgc ccatgtggcg ttttttcgaa
     7321 ttctagtgtt tttacttgcg taaaaaaatt ttttctagta taatagttta ttgtgagcga
     7381 acctcactta ccccttgcaa agtcttgggg tcattagacc aaaaggagga acatatcaat
     7441 ggctaaatac gaaattcttt atatcattcg tccaaacatt gaagaagaag ctaaaaacgc
     7501 tttggtagca cgttttgact ctattttgac tgacaacggt gcaactgttg ttgaatcaaa
     7561 aacttgggaa aaacgtcgtc ttgcatacga aatccaagat ttccgtgaag gactttacca
     7621 catcgttaac gttgaagcaa atgacgatgc agctcttaaa gagtttgacc gtctttcaaa
     7681 aatcaacgct gacattcttc gtcacatgat cgtcaaaatt gacgcgtaag aaggtaaact
     7741 atgattaaca atgttgtact tgtagggcgt atgacacgtg acgctgagtt gcgttatacc
     7801 ccatcaaatg tagcagttgc gacttttact cttgcagtaa accgtacatt taagagtcaa
     7861 aatggtgaac gtgaggctga ttttatcaat gtcgttatgt ggcgccaaca ggctgaaaat
     7921 cttgctaact gggctaaaaa aggctcactt atcggggtga caggtcgtat ccagactcgt
     7981 agttacgata accagcaagg acaacgtgtc tacgtgacag aggtcgtggc tgagaatttc
     8041 caaatgttgg aaagccgtag tgtgcgtgag ggccacacag gtggagctta ctctgcacca
     8101 actgcaaact attcagcacc tacaaattca gtaccagact tttcacgtaa tgaaaatcca
     8161 tttggagcaa caaacccatt ggatatttca gatgatgatt taccattcta atggacaact
     8221 aaacttataa aggagaaaaa acatggctca acaacgtcgt ggcggattca aacgccgtaa
     8281 aaaagttgat tacatcgcag caaacaaaat tgaatatgtt gattacaaag atactgagct
     8341 tcttagccgt ttcgtttcag aacgtgggaa aatccttcct cgtcgtgtaa caggaacttc
     8401 agctaaaaac caacgtaaag taacaacagc tatcaaacgc gctcgcgtaa tggctttgat
     8461 gcctttcgta aacgaagatt aaagaaaaga cccggttggg tctctttttc atgagcttga
     8521 aaacaagaaa gcgaattaag accccaacgg gtcttttttc acaagctttg aaatgagaga
     8581 gcgagttagg ctcagtggct ccctttttac gagtttgaaa acaagagaac acattaaaag
     8641 cacgatggag ctttttcata aatatgtctt ttttctcatc caagaaatta aaataaaaat
     8701 gataaacttt ttgaaaatag gggatttgcc tactttatga tataatggaa agagttagat
     8761 tgaaagaggt agtgagatgg acgcgaaatt aagatacaag gcaaagaaga tcaagattgt
     8821 cttttttgat attgatgata cattgcggaa ttcaaagaca gggtttattc caactacaat
     8881 tcccactgtt tttaaacagt tgcgtgaaaa aggaatttta acaggaatcg cctctggacg
     8941 tggcattttt ggtgttgttc cagagattcg tgatctcaag cctgactttt ttgtaacttt
     9001 gaatggagct tatatcgaag ataaaaaagg tcaggtcatt tatcagcatc agattgaaaa
     9061 gtcagatgtt gaggagtata tctcttgggc taagcaagaa ggaattgagt atggcttggt
     9121 tgggagtcat gatgccaagt tgtcgactcg caccgatatg atgagtgaag ctatcaatcc
     9181 aatttatccc gacttagatg tagatcccga tttccatgaa aaagaagata tctatcagat
     9241 gtggactttt gaagataagg gagatgactt gcacttgcct gacagtctct cagacaaact
     9301 tcgcatggtt cgttggcatc aacattcgtc tgatattgtg ccgatttcag gctccaaagc
     9361 gacgggggtg gaaaaggttg tggaacacct tggcttgaaa ccagagaagg tcatggtttt
     9421 tggagatggt ctcaacgact tggaactctt tgattatgct ggaatcagcg ttgccatggg
     9481 aatttctcat gataaaatca aagaaaaagc agattatatt acaaaaacat tagaagaaga
     9541 tggcattttt gatgccttag aagtatttgg tatggtagaa aaagaattgc attttccaca
     9601 agtagacatt gaaacagtag aaggtcctct tgcgactatt aagaccaatc acggagactt
     9661 acgtatcaag cttttccctg aacatgctcc taaaacagtg gctaactttg tatctctttc
     9721 aaaagatggc tactatgatg gtgtcatttt ccaccgtatt atcaaggact ttatgatcca
     9781 aggtggagac ccaactggaa ctggtatggg tggcgagtca atctacggcg aatcttttga
     9841 ggatgaattc tcagaagagc tttacaatat ccgtggtgct ctttccatgg caaatgctgg
     9901 tccaaatacc aacggcagcc agttctttat cgtgcaaaac caacacctac cttattcgaa
     9961 gaaagaaatt actcgtggtg gttggccaga accgattgca gaaatctatg ccaatcaagg
    10021 tgggacacct cacctagacc gccgtcacac ggtttttggt cagttagctg atgaagcatc
    10081 ttacgctgtc ttggatgcca ttgctgctgt tgagacagga gctatggaca agccagttga
    10141 agatgttgta attgaaacta ttgaaatcga ggactaagat gaaaatcggt gataagctaa
    10201 aggggcgtat tacagggatt cagccctacg gtgcctttgt tgagttagag acgggtgata
    10261 cggggctgat tcacatttca gaaattcgga caggatttat tgaaaatatt catgaaacct
    10321 tgaaagtcga tgaagaggtt caagttcagg tagtggattt agatgaattt acggggaaag
    10381 ccagtctttc tatccgcact ttggaggaag aaaagtacca gtttcctaga cggagacgct
    10441 tttcaagcga ccgctttaac tacggttttg ctccctttcg acgaatgcta ccaatctgga
    10501 ctggagaagc cctgcaccat ttaaaaaaga agaagtagtt tagagtttta tattttttgt
    10561 aatgttaata tgaatttgct ataataggac catggaagaa gaacaattat taaaatcagg
    10621 agagcgcatt aaccagctct tttcgacaga tatcaaaatc attcaaaata gagaggtttt
    10681 tagctattcg gtggatagtg ttctcttatc acgatttcca cgttttccta agaaggggtt
    10741 gattgtggat ttctgtgctg ggaatggagc agtggggctt tttgctagca ctcgtactca
    10801 agcacagata ttgtctgttg agattcagga gcgtttggcg gatatggctg aacgctctgt
    10861 ccgtttgaat ggattagagg agcaaatgca ggtcatctgc gatgatttga aaaatatgcc
    10921 tgctcacatt caggggagta aggtggatat gattttgtgt aatccaccct atttcaaggt
    10981 gaatccttat tctaatctga acgagagtga acattatctc ttggctcgac acgaaatcac
    11041 gactaatttg gaagaaatct gtcgtagtgc ccagagtatt ctcaagtcta atgggcgttt
    11101 ggccatggtt catcgtcctg atcgacttct ggatattttg gatacgttaa aacgacataa
    11161 tctagcccct aagcgcctgc agtttgttta tccaaaaaga gaaaaggaag ccaatatgct
    11221 tttgattgag gcgatcaagg atggctcaac aagtggcttt aaggtcttac ctcctttgat
    11281 tgtccacaat gatgatggct cttatacgcc cgaaatcgaa gagatttatt atggatcata
    11341 aggcttatat gtacgttctg gagtgtcgtg atggatccta ctatataggc tatacgactg
    11401 atatgagaag acgcctcgct atccacaata gtgggaaggg agccaaatat acacgagcac
    11461 gcttgccagt caaacttatc tatgctcaag gttttgccag taaggaagaa gccatgtcgg
    11521 ctgaagctct tctcaagcgt aagaagaggc cacagaagga agaattttta tctgaaaatc
    11581 aagatagaaa tttactcagt tattttgaag aatcgtgggg agtcctttga ctcctcttac
    11641 ctttgtcaaa aagcgaaaaa aatgctacaa taaagaaaat aaacaaaatg aggtattatc
    11701 atgtccaaga ttctagtatt tggtcaccaa aatccagact cagatgccat cggatcatct
    11761 gtagcttttg cctaccttgc aaaagaagct tacggtttgg atacggaagc tgttgccctt
    11821 ggaactccaa atgaagaaac agcctttgtc ttgaactatt ttggtgtgga agcaccacgt
    11881 gttatcactt ctgccaaagc agagggggca gagcaagtta tcttgactga ccacaatgaa
    11941 ttccaacaat ctgtatcaga tatcgctgaa gtagaagttt acggtgttgt agaccaccac
    12001 cgtgtggcta actttgaaac tgcaagccca ctttacatgc gtttggagcc agttggatca
    12061 gcgtcttcaa tcgtttaccg tatgttcaaa gaacatggtg tagctgtgcc taaagagatt
    12121 gcaggtttga tgctttcagg tttgatttca gatacccttc ttttgaaatc accaacaaca
    12181 cacccaacag ataaaatcat tgctcctgaa ttggctgaat tggctggtgt gaacttggaa
    12241 gaatatggtt tggcaatgtt gaaagctggt accaacttgg ctagcaaatc tgctgaagaa
    12301 ttgattgata tcgatgctaa gacttttgaa ctcaacggaa ataatgtccg tgttgcccaa
    12361 gtgaacacag ttgacatcgc tgaagttttg gaacgccaag cagaaattga agctgcaatg
    12421 caagctgcca acgaatcaaa cggctactct gactttgtct tgatgattac agatatcgtc
    12481 aactcaaact cagaaatctt ggctcttggt gccaatatgg acaaggtcga agcggctttc
    12541 aacttcaaac ttgaaaacaa tcatgccttc cttgctggtg ccgtttcacg taagaaacaa
    12601 gtggtacctc aattgactga aagctttaat gcgtaagatt ttgggtgtca gctcaaaatc
    12661 ggaaagtcta gtttgcctta tatcgaaagg agtttcggct ccttttttct aggagtgaag
    12721 tatgttagaa aatggcgatt tgatttttgt gagagatggg tcagacatgg gacaggccat
    12781 ccagacttcc acaggtaact atagccatgt tgccatttat ttggatggga tgatttatca
    12841 tgctagtgga caggctggtg ttgtctgtca agaaccggca gacttctttg agtccaatca
    12901 tttatacgac ctctatgttt acccagaaat ggatatccag tcggtgaagg aaagagcttg
    12961 caaacatctt ggagcaccct acaatgcttc tttctatcca gatgcacctg gtttctactg
    13021 ctcccagtat atagcagaaa tcctacctat ttttgaaact attcctatga aatttggaga
    13081 tggggagcag gagattagtg atttttggag ggagtattac atagaactag gtctgcctgt
    13141 tcctctgaac caagctggta ccaatcctag tcagttggca gcatcgcctc tgttacaatg
    13201 taaagaaagg aatcttcatg attcagattt ttaatccatc tcgtttgacg agacagccat
    13261 ttttggagaa ttgatccgct atctggacca gtatgaggat gtgattctac gggaaattaa
    13321 ggctcaattt ccagatgttg cagttgataa actcatggaa gagtatataa aggcaggctt
    13381 gattctacgt gaaaataagc gctattacct caattttcct acgcttgaat cacttgatag
    13441 tcttgaactg gatcaagaga tttttgtcag agaagctagt ccggtctatc aagccttgtt
    13501 ggagcagagt tttgagacgg aattgcgcaa tcaaatcaat gcagctattt tagttgaaaa
    13561 gacggacttt gcgcgcatta aaatgactct gtccaattat ttttacaagg tcaaacagca
    13621 gtatcctttg acagaaaaac agcaggagct ctatgacatt ttaggagatg ttaatcctga
    13681 gtatgcactc aagtatatga cggctttttt gttgaaattt ctcaaaaaag accagcttat
    13741 gcagaaatgc cgtgatatct ttgtggacag tttggttgtc ttaggctata ttgtgcaaaa
    13801 tgaagatgga aagtatgagt tggctatcga ttttgataag gagagattaa ctttctactt
    13861 agcgtgattt cttgtttctg agtacattgt ttgactttcc ttagtattcg gtataaacta
    13921 tatgtaaccg gtaacacata tcggaataaa ctaaaggaga caatcatatg tcacttgaaa
    13981 acaaattgga acaagcaaca ggcgctgtca aagaaggttt tggtaaagtt actggagaca
    14041 gcaagacaga acttgaagga gctgttgaaa aaacagttgc taaggcaaaa gacgttgtag
    14101 aagacgcaaa aggtgctgta gaaggtgccg ttgaaggttt gaaaaacgtt tttactaaag
    14161 aataggaaaa aatcaagggt ttcattttcc cttgattttt tctattctta taaataattt
    14221 tctgcgacgg ctgtatctcc tgggtaggat tctttcttgc cctggatgat ttggtaacaa
    14281 tcggctccct tacccgcaat aataactgca tctaattcgt gatttgtgat agccattgcc
    14341 gccttgatgg cttcttggcg atccgcaatc ttctcaacag gatgattgat gtagctacta
    14401 atttcatctg caatggccat tgggtcttca tagttagggt catcagcagt cagaaagact
    14461 tgaatctcag ggtgttgatt gaggaggagg ccaaagtcct tacgacgact ttctcccttg
    14521 tttcctgttg atcccagaac cagagcaatc tttccggttt gatgagtttc aaccacattg
    14581 atgagttttt tcagactatc cccattgtgg gcatagtcga tgaagacctt ggctccattt
    14641 ttctgagtga ggacttccat acgaccagga acgcgggttg cagcgatgcc ttttttgatg
    14701 tcctcaagac ttgctccgag acggagacaa gcaagtccag cagcaactgc attttcttgg
    14761 ttgaagttgc caatgagttg gatatcataa tctccagcga gtttacccgt agctgaaaag
    14821 ctaaaggctt tggaattctc gatttggtta tcaaattggc taccatagaa atcatggtct
    14881 tgatctttaa cctgttcttt caagactgag aagtggtcca tgtcactgtt aatgatgact
    14941 gctcggctat tttccatcaa gagacgcttg tggtagaaat agtcttcaaa gctagggtgt
    15001 tcaatcgggc cgatatggtc tgggctgata ttgaggaaaa ctcccacatc aaaggttaga
    15061 ccatagacac gtctgaccag ataggattga ctggagactt ccatgatgag gtgggtacgg
    15121 tcattttgca cagcctgatt catcatgtca aagaggtcaa tactctcagg ggttgtcaac
    15181 gctgacttaa agaaagtctc gccatcaaga gttgtgttca tggtcgacaa catagcaggt
    15241 cgatgccctt gagataagat gttataggcg aaataggctg ctgttgtctt acccttagta
    15301 ccagtaaagg caaggagttt gagtttttcc tgtggattac catagaactc catggcaatc
    15361 aaactcatgg ctttctttat atcgttcaca atgatgacag ggataccgac ttcgtagtcc
    15421 ttttcagcta cataccaagc taagccttgt gttatagcag aaagaaggta ttctttttta
    15481 aaggcagcgc cttttgcaaa aaaaagagtg tcttctgtta cttttcggct gtcgtagctg
    15541 atgctatcaa aaacaacttt gctgtagttg tagtggtaat gaccttggtc aataatttcg
    15601 cgaaaaaggc catctttctt taaaatatct aatacagttt caatttttat catactttct
    15661 attgtaaacc gaaagtcgca aatttacaag taacaaggaa aagtttataa tggaagataa
    15721 ggagtttttc ctagttatca aaattgaatg aggaatctat gtcgcacgaa aacaatcacc
    15781 agcaggccca gatgttacgg gggactgctt ggctaacggc tagtaacttt atcagtcgcc
    15841 tactcggggc tgtttacatt atcccttggt acatctggat gggggcttat gcagctaagg
    15901 caaatggtct ctttaccatg ggttacaata tctatgcttg gttcttgttg gtttcaacag
    15961 cggggattcc agttgcggtg gccaagcaag ttgccaagta taataccatg cgagaagaag
    16021 agcatagctt tgccctgatt cggagcttct taggctttat gacaggacta ggcctggttt
    16081 ttgctttagt cttgtatgtc tttgctcctt ggctagcaga cttgtctggc gtgggcaaag
    16141 acttgatccc aatcatgcaa agcttggctt ggggagtctt gattttcccg tctatgagtg
    16201 ttatccgagg atttttccaa gggatgaata acctcaaacc ctatgccatg agccaaattg
    16261 ctgagcaggt cattcgtgtt atctggatgc tcctagcaac ctttatcatt atgaagctcg
    16321 gttcaggaga ttatctagca gccgttaccc aatcaacctt tgctgccttt gtcggtatgg
    16381 tagccagttt tgcagtcttg atttatttcc ttgcccaaga aggttcactc aaaagagtct
    16441 ttgaaacagg agataagatt aacagtaagc gtctcttggt tgataccatt aaggaagcca
    16501 ttccttttat cctgacaggg tctgccatcc agctcttcca gattttggat cagctgacct
    16561 ttatcaatag tatgagctgg tttaccaact acagcaatga ggacttggtt gtcatgtttt
    16621 cttatttctc agccaatcct aataaaatca cgatgatttt gatttctgta ggggtttcga
    16681 ttgggagtgt tggtttgcca cttttgacgg aaaactatgt caagggggac ttgaaagcag
    16741 cttctcgtct ggttcaggac agtctcaccc tactctttat gttcttgcta ccagcaacgg
    16801 ttggagtggt tatggtagga gaacctctat atacagtctt ctatggtaag ccagatagtt
    16861 tggctctggg cttatttgtc tttgcagttt tgcagtctat tattttaggc ttgtacatgg
    16921 tcttgtctcc aatgcttcag gccatgttcc gcaaccgcaa ggccgttctc tattttatct
    16981 atggttctat tgccaagcta gtcttgcaac tacctaccat cgccctcttc cacagttatg
    17041 gtcctttgat ttcaacaacc attgctctca tcattcctaa cgtcttgatg tatcgggata
    17101 tttgtaaagt aactggtgtc aagcgcaagg tgattttgaa gcgaaccatt ttaatcagtt
    17161 tgctgaccct agtcatgttt ctgttaatag gaaccatcca gtggctgtta ggatttttct
    17221 tccaaccaag tggacgtttg tgtagcttct tttatgtagc tcttgtcggt gccatggggg
    17281 gtggacttta tatggttatg agtctgcgta cctatttatt agataaggta ataggaaaag
    17341 cccaagcaga tcgcctgcga gcaaaattta agctttcgta aggtagcatt tataaataaa
    17401 aggaataagt tgaacaatct tttaggagaa cttgaagctt attccttttt tagcgtaaaa
    17461 atagctaaaa ttatatttca aaaatagaaa atgaggcttt tttcgatttt ttggaaaaaa
    17521 tcattgacta aacaaactaa acgttgtata ataaaacaaa tatttaaagc aggaggttcc
    17581 ggaaatgaaa aagtctaaga gcaaatatct aaccttggca ggtcttgtcc tgggtacagg
    17641 agttttattg agcgcgtgtg gaaattctag cacggcgtca aaaacataca actatgttta
    17701 ttcaagtgat ccatctagct tgaactatct agcagaaaac cgcgcagcaa catccgatat
    17761 tgttgcaaat ttggtagacg ggttattaga aaatgaccaa tatgggaata ttattccatc
    17821 attagcagag gattggactg tttctcagga cggtttgacc tatacctaca aacttcgtaa
    17881 ggatgccaag tggtttactt ctgagggaga agaatatgcg cctgtaactg cccaggattt
    17941 tgtgacaggt ttgcaatatg cagctgataa aaaatcagaa gccttgtatc tagtgcagga
    18001 ctctgttgct ggtttggatg actatatcac tggtaaaaca agcgactttt caactgtcgg
    18061 tgtcaaggca cttgatgacc aaacggttca atatactttg gttaaaccag aactttactg
    18121 gaattcaaaa acacttgcaa cgatactttt tcctgttaat gcagatttcc tgaaatcaaa
    18181 aggggatgat tttgggaagg cggatccatc tagtattttg tacaatggac ctttcttgat
    18241 gaaagcactt gtctcaaaat ctgctattga atataagaaa aaccctaatt actgggatgc
    18301 taagaatgtc tttgtagacg atgtgaaatt gacctactat gatggtagcg accaagaatc
    18361 actggaacgt aattttacag ctggtgctta tactacggct cgtctttttc ctaacagctc
    18421 cagctatgaa gggattaaag aaaaatacaa aaacaatatc atctatagtg tgcaaaattc
    18481 aacttcatat ttctttaatt ttaacctaga taggaagtct tacaattata cttctaaaac
    18541 aagtgacatt gaaaagaaat cgacccagga agcagttctc aataaaaact tccgtcaggc
    18601 tatcaatttt gcttttgaca gaacatctta tggggctcag tctgaaggga aagaaggtgc
    18661 aacaaagatt ttgcgtaacc tagtggttcc tccaaacttt gtcagtatca agggaaaaga
    18721 ctttggtgaa gttgtagcct ctaagatggt caactatggt aaggaatggc aaggtatcaa
    18781 ctttgcggat ggtcaagacc cttactacaa tcctgagaaa gccaaggcta agtttgcgga
    18841 agctaagaaa gaactcgaag caaagggtgt tcaattccca atccacttgg ataagactgt
    18901 ggaagtaaca gataaagtag gcatacaagg agttagttct atcaaacaat caattgaatc
    18961 tgttttaggt tctgataatg tagtgattga cattcagcaa ttaacatcag atgagtttga
    19021 cagttcaggc tactttgctc aaacagctgc tcagaaagac tatgatttat atcatggcgg
    19081 ttggggacct gattatcaag acccgtcaac ctatctcgat atttttaata ctaatagtgg
    19141 aggagttcta caaaatcttg gactagagcc tggagaagcc aatgacaagg ctaaggcagt
    19201 tggactggat gtctatactc aaatgttgga agaagctaat aaagagcaag atccagccaa
    19261 acgttatgag aaatatgctg atattcaagc ttggttgatt gatagttctt tagttcttcc
    19321 aagtgtttcg cgtgggggaa caccatcatt gagaagaacc gtaccatttg ctgctgccta
    19381 tggtttaacc ggtacaaaag gggttgaatc atataaatac ctcaaagtac aagataagat
    19441 tgtcacaaca gacgaatatg caaaagccag agaaaaatgg ttgaaagaaa aagaagaatc
    19501 caataaaaaa gcccaagaag aattggcaaa acatgtcaaa taaaatctaa ttgtagataa
    19561 gtttgtgtaa gaagtctttg tgcttaaaaa cgcataatat caggtatata aaatcctaga
    19621 tgttatgcgt tttgttatag gaagatttat tagattttat cctcaaattg agttattccc
    19681 gactttatcc gttgaaatat tataaggagt atttatgaaa ttaaaattat taagagtaga
    19741 tactaaggtg attatgggga gtttcttact tgttctgtct agtctacttg ctttgttgct
    19801 tccccttatc ttaaagggtt taatagatgg gagttctatt gaaaatatag gttccaaagt
    19861 atttcaatcg tttttgattt ttattggtca agccttgttt tcttctattg gttactatct
    19921 gtttagtcaa tcgggtgaaa aaagatagca aaaatcagga aaaaagtgat agaggggttg
    19981 atttatgcag agaaatcctt ctttgataag agccaaagtg gggagttgac ttctgccatt
    20041 gtcaatgaca tgagtgtcat tcgtgagttt ttaattacga ctttcccaaa tattattctg
    20101 agtttagtta tggtacttgg ttccattgta gtcttattta gtcttgattg gaatctttct
    20161 ctacttttat tcatcactct tccttgtatg atgtttatta tcttgcccct ttccaatatc
    20221 agtgaaaagt atagtcgtcg tttacaggag gaaatcggat ttttaacagg gcaattgact
    20281 gaaaagattc aagaacatga attaattaag actaaccaag cagagaaaag tgtacaggat
    20341 gttttggata attgtattga aagggtacaa aacaattcac tgaaatcaga tagggttact
    20401 tcttttgaga ccccgtttgc tctcttattt atctttgcga ctatagttgt gatgctaacc
    20461 tatgggggtt atcgggtcag cgcaggatat atatctgtgg gaaccttggt ttcgtttttg
    20521 atttacctct ttcaattact taatcctatt agtaatatag ctaattttgt aactatttat
    20581 tctagtagca agggatcttc agttgcactg gagaacttgc ttgcagttcc taaagaaaaa
    20641 tttgagggag gaaaatcggt atcaggacaa gggttgaatt ttaaccatgt ctattttggt
    20701 tatgatgaaa atcgacctgt cttaaaggat attacttgtt caattttcaa ggggcaaaaa
    20761 attgcttttg ttgggccatc tggatcagga aaatcaacga ttgtgcgttt gttagagcgg
    20821 ttttataaac cgctttcagg agatattcta atggagcaat caagtatata tgattttaac
    20881 ttaaaagaat ggagaagtaa aatcgcttgg gtttcacaaa ataatgcagt cttatctggc
    20941 agtattcgtg acaatctttg tctcggtttg aatcgcttag taactgatga tgaattgatg
    21001 aaagtgctag acttagtatc actaggtgat gagattcgct ccatgaaaga gggactagat
    21061 actgaagttg gtgaacgcgg acgactcttg tcaggggggc gaagccaaag acttcaaata
    21121 gctagagcct acttaaaaga tgctgaaatt cttatatttg atgaagccac tgctaatctt
    21181 gatgcggatt ctgagtatgc gattatcagt agcctctatt ctgtactaaa ggagaagacg
    21241 gttgtgatta tagcgcatcg cttgtcaacg gtaaaagatg tggattgtat tttcttctta
    21301 gaggagggga aaatcactgg ctcaggaact cataaggaac tactggaaaa tcatgagcgt
    21361 tatgctcgtt ttgtgcagga gcaaatgata gagtgaaggt gtcttttgag attcaccatt
    21421 ttatagtcta ttaaagggag caggaaaaac tcccttttta tatagtttga aactataact
    21481 agctcttgaa aagaagaaaa tgagttgatg aaaataagtg gtacaatagt tactatagat
    21541 ttggaggaat tgtatgagca aggaattaca cattaacaca attttagcac aagcagggat
    21601 caagtctgat gaggcaacag gtgctttggt gacaccactt catttttcaa cgacctatca
    21661 gcatccagag tttggtcgat ctactgggtt tgactatacg cgcactaaaa atccaactcg
    21721 tagtaaggct gaggaagtct tggcggctat tgagtcagca gactatgccc tagcgactag
    21781 ctcagggatg tcagctattg tactggcctt tagcgtcttt ccagtaggaa gtaaggtctt
    21841 ggcagtgcgt gatctttacg gtggttcttt tcgctggttt aaccaagtgg agcaggaagg
    21901 tcatttccat tttacctatg ccaatacaga agaagagttg attgccgagt tagaaaagga
    21961 tgtggatgtt ctctatatcg aaaccccaac caatcccttg atgttggaat ttgatatcga
    22021 aaaactagca aaattggctc atgctaaggg tgccaaagtg gtggtggaca ataccttcta
    22081 tagccctatc taccaacgtc cgattgaaga tggagcagat atcgttctcc attcagcaac
    22141 caagtatcta gcaggccaca atgatgtctt ggctggagtg gttgtgacca atagtttaga
    22201 actatacgag aagctttttt acaatcttaa tacaacaggg gcagtcttgt ctccatttga
    22261 cagctaccag ttgcttcgtg gtctcaagac cttgtctctt cgtatggagc gctcaacagc
    22321 taacgcccaa gaagtggttg cctttttgaa ggattctcca gcagttaagg aagttctcta
    22381 cactggtcgt ggaggcatga tttcctttaa agtagccgat gaaacacgca ttcctcatat
    22441 tttgaacagt ctcaaggtct tctcttttgc ggaaagtttg ggtggagtgg aaagtcttat
    22501 tacttatcca acgactcaaa ctcatgctga tattccagca gaagtacgcc attcttatgg
    22561 tttgacagat gacctcttgc gtttgtctat tgggattgag gatgctagag atttgattgc
    22621 agatttgcgc caagccttag aaggataaga caaagatggg aaaatatgat tttacaagcc
    22681 tgcccaaccg tttagggcac catacctata aatggaaaga aacagaaacg gatagtgaag
    22741 ttctaccagc ttggatagcg gatatggact ttgtagtctt gcctgaaatc caccaagccg
    22801 tgcaaactta cgcagaccaa ctggtttatg gttataccta tgccagtgaa gacttaatta
    22861 aggaagttca aaagtgggaa gctacacaat acggttacaa ctttgacaaa gaggctcttg
    22921 tctttatcga gggtgtggta ccagccatct caacagctat tcaaaccttt acaaaagaag
    22981 gcgaggcggt tttaattaac acgcctgtct acccaccctt tgctcgcagt gtcaagttga
    23041 ataatcgtag attgattact aattccttag tggaaaagga tagtctgttt gagattgact
    23101 ttgaccaact tgaaaaggat ttggtggaag aggaggttaa actctatgtt ctttgcaacc
    23161 ctcacaatcc tggtggacgt gtttgggaaa aagaagtgtt ggagaagatt ggccaactct
    23221 gccaaaaaca cggtgttttg ttagtttcgg atgagattca ccaagatttg accctctttg
    23281 gtcacaaaca ccagtctttc aataccatca atcctgcctt caaaaatttt gctatcgtct
    23341 tgagcagtgc cactaaaaca tttaatattg ctggaacaaa aaattcctat gcagtcattg
    23401 aaaatcctaa gttgagactg gctttccaga aacgcctgtt ggccaataat cagcatgaaa
    23461 tttcaggctt gggttatttg gcgacagaag ctgcctatcg atacggtaaa gattggctag
    23521 aggaactcaa gcaagtcttt gaagaccaca tcaattatgt ggtggatcta tttggaaaag
    23581 agactaaaat caaggtcatg aaaccgcaag gtacctactt gatttggctt gacttttcag
    23641 cttatgacct gactgatgaa acattgcaag agttgttgag aaatgaagcc aaggttatcc
    23701 tcaaccgtgg tttggatttt ggagaggaag gaagtctcca tgcccgcatc aatatagcta
    23761 tgcccaaatc tctgttgcaa gaagtctgtc agcggattgt ggctactttt gccaaatgtt
    23821 aaaaatccag ccttctagga gaaaagtctt cctagaaggc tattttcata ggcgaaaata
    23881 tggtataata aaaagataag gtaaaggtga aaatatggct aaattgattc cggggaaaat
    23941 tcgtatcgaa ggtgttgccc tttatgaaac tggtaaggtt gatatcatca aggaaaagaa
    24001 caatcggctc tacgctcgcg ttgcagaaga agaactgcgc tatagtttag aggatgattt
    24061 gattttttgt gcctgtgatt tttttcaaaa gaggggctac tgtgtgcatt tggcagcgct
    24121 agagcatttt ctgaaaaatg atgagcgtgg tcaggaaatc ttgtggagtc tggaagaagg
    24181 tcatgaagaa aaagaggccg ttgaaaccaa ggtgaccttg ggtggcaagt ttttggatcg
    24241 aattttatct ccaaaatcag aatgcgccta tgagttatca gctgtgggtc aggtggaagc
    24301 aggaaccaat catatcttgt ggactctgag aatcggccaa atcaatagcc aaaaatacta
    24361 tgtcattcgg gatattccac tttttttaag gattgtcgag cagagaaagt cgtatatgat
    24421 tggcaagatt tatgaggagt ctctttcttg ggaagccttt gatgatgcca gccaagaact
    24481 tttgactttc ttgcacggac taacggagga agggctggtt ccagacctct ttttccaaaa
    24541 ccaaggtcgg cacctctttt tccctctgac cttttttgag cagggtgtga atttactgat
    24601 ggccttgccc cattttcaat ttgaccatca agtggatagc taccaaaccc tgctttttca
    24661 ggatatgcat gctgatgcca atctatttgc ctttacagta acagaatatt cggactattt
    24721 tgaaatggaa atcagtgaga gtcctagggt caatgtcttt tatcaaggag cagtactttt
    24781 ccataaaggt caggtttatt ttttaacaga ccagcagatg cgtcttctca aggaaattaa
    24841 agcgttacct gtggatcgac aaggaaagaa atacctgcaa tttgatagca gtgatcgaga
    24901 caaattggcc tcctgtctga ctctttttat ccagatgggc accgtttcag ctccagaacg
    24961 tctacaaatc aaaacttttg cgccctcttt ttactttgac agggaagaag ataatcggat
    25021 tcgtttagaa attcagtttg attatggaaa tagacaggta tctagccgac aagagctaga
    25081 agaattacca ttttcaagtg acgcggactt agaagaaaga attttccaag tctgtttggc
    25141 tgcgggcttt gaagccgatt ttcaatcttg gcgtcaggcc ttaaaagcgg agtctgtcta
    25201 tcattttttt catgatatca ttccagtctt tgaaaaactc gggcatgttg acctatcaga
    25261 taaactagaa gagctttata gcctagcgag tcctcaggtg cagattgcct ccaagggagg
    25321 tctcttggaa atccagtttg attttcaaga tattgcccag gaggaaatcg accaagccat
    25381 acaggccttg gttgccaatc aggattttta tattgattcg tctaatcaag tttacttttt
    25441 cgatgaagaa accaagaaaa ttcgccaaaa tctacaggaa ctggggcaat ttgaattaaa
    25501 agatgggacc ttgcaggctc ggaaatcctt ggcctacagt ttagctcatc tctttgaagg
    25561 gcgagaccgt gtttcttttt cacaagaatt ccagaatctg gcccaggatt tgacgcatcc
    25621 agaggacttt cctttgcaag caactcaggt caaggctgac ttgcgagatt atcaggaaaa
    25681 gggaattggc tggttgcaga tgctccatca ttatggtttt ggtgggattt tggctgatga
    25741 tatgggactt gggaaaaccc ttcagaccat tgcttttttg actagtcaag tgacaaaaga
    25801 aagtcgggtt ttgattctcg ctccgtcggg tttgatttac aactgggcag atgagtttca
    25861 gaaatttgct ccacagttgg atgtggctgt tgttcatggt ttgaaagcaa gtcgtgagga
    25921 gattcttgcc gagagccatc aaatctatgt gactagctat gccaccttcc gtcaggacag
    25981 tgagctttat caggggatgg cctttgactt ccttttctta gatgaagctc aggtcatgaa
    26041 aaatgcccag accaagattg cccagacctt gagacaattt gtggtgccgt cggtctttgc
    26101 cttgtcagga actccgattg aaaaccatct gggtgagttg tggtctattt ttcaaatcgt
    26161 catgcccgga cttttgccaa gcaagaaaga atttatgaaa ttgccagcag agcgagtggc
    26221 tcagtttatc aagcctttcg tgatgcgacg caagaaagaa gaagttctga ctgaattgcc
    26281 agacttgatt gaggtggttt ataaaaatga actggaagac cagcaaaagg ctatttacct
    26341 tgcccagtta caacagatgc gagaccatct ggctcaagtg tcagaacagg aatttcagcg
    26401 aagtcgtgtg gaaattttat ctggtttgat gcgcttgcgt caaatatgtg acactcctgc
    26461 cctgtttatg gaagattatc agggagccag cggcaaacta gatagtctcc gagacctact
    26521 ggtacaggtg gcagacggcg gacaccgtgt cttgattttc tctcagttca agggaatgtt
    26581 ggaaaaaatt gaacaagaac tgccagactt gggcctgaca tcctttaaaa ttacgggttc
    26641 aaccccagcc aaggaaagac aagacatgac caaggccttt aaccaaggag aaagagatgc
    26701 ctttctgatt tccctcaagg ctggtggggt cggtctgaac ctgacaggtg cagatacagt
    26761 gatcttggtt gacctttggt ggaatcctgc ggtggaagcg caagccattg gccgtgccca
    26821 tcggatgggt caggaagaaa cggttgaggt ctatcgcttg gtgaccaagg gaaccattga
    26881 agaaaaaatt caggaactcc aagaacaaaa gaaacatctg gtgtcacaag tattggacgg
    26941 cacagagtca cgtggtagtc tgaccctagc agaaattaga gaaattttgg gaatttctga
    27001 agccagcact tgaaaaatca agacaatacg ctataatgaa gtgttgaaag gaaatagaaa
    27061 atgaaacaag aacgatttcc attggtgtca gatgacgagg tcatgttgac tgaaatgcca
    27121 gtcatgaatc tctatgatga gtctgatctg atcagtaata tcaagggtga gtatcgagat
    27181 aaaaattatt tagaatgggc tcctattgct gaagaaaaac cagtaaaacc gattgaaaag
    27241 caagtaggga aacctaaaaa agctccttta ggggttaaaa aagaaggaaa gagctatgcg
    27301 gaggtggcgc gtgaagaagc gcgtgcagac ttgaaaaaga aacgctctgc taactatcta
    27361 actcaggatt tcagccttgc gagacgtcat tctcagccca gtctagttag acagggcaat
    27421 caaccgacaa ctcctttcca aaaggaaaat cctggtgaat ttgtcaaata tagccaaaaa
    27481 ttgacccagt ctcattatat cttggcggaa gaagttcatt ctatccctac caagaatgaa
    27541 gaagtgtcag cacctgctcc aaagaaaaac aattatgatt ttctaaagaa gagccaaatc
    27601 tacaataaaa aaagtaaaca aacagaacaa gaacgtcggg ttgcccaaga gttgaatctg
    27661 accagaatga cagaataggg gagaaaacat gtcaaagaca tatcatttta tcggaattaa
    27721 gggatcaggg atgagtgcct tggccttgat gttgtaccag atggggcaca aggttcaggg
    27781 atcagatgtt gaaaagtact actttaccca acgcggtctt gagcaggcag gaattaccat
    27841 tcttcctttt gatgaaaaga atctagacgg tgatatggaa attatcgctg gaaatgcctt
    27901 tcgtccagat aacaacgtcg aaattgccta tgcggaccaa aatggtatca gctacaaacg
    27961 ttaccatgag tttctaggta gctttatgcg tgactttgtt agcatgggag tagcaggagc
    28021 acatggaaaa acttcaacga caggtatgtt gtctcatgtc ttgtctcaca ttacagatac
    28081 cagcttcttg attggagatg ggacaggtcg tggttcggcc aatgccaaat attttgtctt
    28141 tgaatctgac gaatatgagc gtcacttcat gccttaccac ccagaatact ctattatcac
    28201 caacattgac tttgaccatc cagattattt cacaagtctc gaggatgttt tcaatgcctt
    28261 taacgactat gccaaacaaa tcaccaaggg tctttttgtc tatggtgaag atgctgaatt
    28321 gcgtaagatt acgtctgatg caccaattta ttattatggt tttgaagctg aaggcaatga
    28381 ctttgtagct agtgatcttc ttcgttcaac aactggttca accttcaccg ttcatttccg
    28441 tggacaaaac ttggggcaat tccacattcc aacctttggt cgtcacaata tcatgaatgc
    28501 gacagccgtt attggtcttc tttacacagc aggatttgat ttgaacttgg tgcgtgagca
    28561 cttgaaaaca ttttccggtg ttaaacgtcg tttcactgag aaaattgtca atgatacagt
    28621 gattatcgat gactttgccc atcatccaac agaaattatt gcgaccttgg atgcggctcg
    28681 tcagaaatac ccaagcaagg aaattgtagc agtctttcaa ccgcatacct ttacaagaac
    28741 cattgccttg ttggacgact ttgcccatgc tttaaaccaa gcagatgctg tttatctagc
    28801 gcaaatttat ggctcggctc gtgaagtaga tcatggtgac gttaaggtag aagacctagc
    28861 caacaaaatc aacaaaaaac accaagtgat tactgttgaa aatgtttctc cactcctaga
    28921 ccatgacaat gctgtttacg tctttatggg agcaggagac atccaaacct atgaatactc
    28981 atttgagcgt ctcttgtcta acttgacaag caatgttcaa taggatgttc ccatggaaat
    29041 tccaattaag atcattcagg caagcaagtc tgatttgcct gagatagggg cacttcagac
    29101 ctcgtctttt ccagctgaaa agcagcaact ttcccatatt ttagaagaaa gtatccgtaa
    29161 gtgtgcggat acctttcttc tagctaggga tgaaaatcaa cttttaggct atattttatc
    29221 aagtccccag tcagacaatc cgcaatatct aaaagtacat tctttagtca tcgagtctga
    29281 ccatcagaga cagggcttgg gaacacttct tcttgcagcc ttgaaagagg tggcagttga
    29341 gctggattac aaagggattc gtttggagag tcctgatgag ctgctttcct attttgaaat
    29401 gaacggtttt gttgatgaag aagcaacttt gctctatgca actagccagg gctatagtat
    29461 gatttggttt aatccctttt atctggagga acaatgaaaa tcagacaagc aagattagaa
    29521 gatttggatc ggattgttga acttgaattt gaaaattttt cggtcgaaga agccattcct
    29581 ccttctgtct ttgaagcaca tttgagagaa attcagacct cttttctggt tgctgaaaaa
    29641 gaaggaagaa tcatgggtta tatcgaagga ccagttggcc tgcaccgcca tctgcaagac
    29701 cagtctttta cagaagaaat aaaagactat agtcatgagc ctggtggtta tatctctgtg
    29761 acctgtctgt ctattgccaa ggaggcacag ggactcggac tgggtcagaa attgctgaca
    29821 gccttgaaag aagttgctct tgaagatgag agagatggca ttaatctaac ctgtcatgac
    29881 tatctcatcg cctactatga aaaacatgga tttgtcaacg aaggccagtc ccagtcaacc
    29941 tttgcagggg aaacatggta tgatatggtc tgggaaatga aaaaataagt taggaaaagt
    30001 atcatagatt gctttttttg gacttttaag atataatatt atggattatc aacaaggagg
    30061 aaaaactttt gagtgaaaag tcaagagaag aagagaaatt aagctttaaa gagcagattc
    30121 tgagagattt agaaaaagta aaaggctatg atgaagttct gaaagaagat gaggcagtag
    30181 ttcgcactcc tgcaaatgaa ccttcaactg aagaactcat ggctgattcc ttgtcaacgg
    30241 tagaggagat tatgagaaaa gctcctaccg tgcctactca cccaagtcaa ggtgtaccag
    30301 cttctccagc agatgagatt caaagagaaa ctcctggtgt tccaagtcat ccaagtcaag
    30361 atgtaccttc ttctccagcg gaagaaagtg gatcaagacc aggtccaggt cctgttagac
    30421 ctaagaaact tgaaagagaa tacaatgaaa ccccaacaag ggtagctgtt tcctatacga
    30481 cggcagagaa aaaagcagaa caagcaggtc cagaaacacc tacgcctgct acagaaacag
    30541 tggatatcat cagagataca tcacgtcgta gccgtagaga aggagcaaaa cccgttaagc
    30601 ctaagaaaga gaagaagtca catgtgaaag cttttgtgat ttcattcctt gtattccttg
    30661 ccttgctctc agcaggtggt tactttggtt accagtacgt gctagattcc ttattaccta
    30721 tcgatgctaa ttctaagaaa tatgtgacgg ttggaattcc agaaggttca aacgttcaag
    30781 aaatcggtac gacgcttgaa aaagctggtt tggtaaagca tggtctgatt tttagttttt
    30841 atgccaagta taaaaattat accgacttga aagcaggtta ctacaatttg caaaagagta
    30901 tgagtacaga agacttactc aaagagttgc aaaaaggtgg aacagatgaa ccgcaagaac
    30961 ctgtacttgc gactttgaca attccagaag gttatacctt ggatcagatt gctcaagctg
    31021 tgggtcaatt gcaaggtgac ttcaaagagt ctttgacagc ggagactttc ttggctaaag
    31081 ttcaagatga gacgtttatc agtcaagcag tagcgaaata tcctacttta ctggaaagtt
    31141 tgcctgtaaa agacagcggt gcgcgttatc gtttggaagg ataccttttc ccagctacat
    31201 actctatcaa ggaaagcaca actattgaga gcttgattga tgagatgtta gctgctatgg
    31261 ataagaacct atctccttac tatagtacta tcaaatctaa aaacttgact gtcaatgagt
    31321 tgttgaccat tgcttccttg gtcgaaaaag aaggtgccaa gacagaagat cgtaagctca
    31381 ttgcaggtgt attctacaat cgtttgaatc gtgatatgcc acttcaaagt aatattgcaa
    31441 tcttgtatgc ccaaggaaaa ctggggcaaa atatcagtct agctgaggat gttgcgattg
    31501 ataccaacat tgattcacct tataatgttt ataaaaatgt aggtctcatg cctggtccag
    31561 tcgatagtcc aagtctggat gcgattgagt caagcatcaa tcaaactaag agcgataacc
    31621 tctactttgt agcagatgtc acagaaggca aggtctacta tgctaacaat caagaagacc
    31681 acgaccgcaa tgtcgctgaa catgtcaaca gcaaattaaa ctaaacaaac taaaattatg
    31741 ttatacttca cataattttc tttagaaaat attatcagaa gaaagttgag aaaaatggca
    31801 gaaaaaacat atcctatgac ccttgaggaa aaggaaaaac ttgaaaaaga attagaagaa
    31861 ttgaaattgg ttcgtcgacc agaagtggta gaacgcatta agattgcccg ttcatacggt
    31921 gacctttcag aaaacagtga gtacgaagca gctaaggatg aacaagcctt tgtcgaagga
    31981 caaatctcta gcttagaaac aaaaatccgc tatgctgaaa tcgtcaatag cgacgcagtt
    32041 gcccaggacg aagtagcgat tggtaaaaca gtcaccatcc aagaaattgg tgaggacgaa
    32101 gaagaagttt atattatcgt aggttcagct ggtgcggatg cctttgcagg taaggtttca
    32161 aatgaaagcc caattgggca ggccttgatt ggcaagaaaa caggtgatac agcaaccatt
    32221 gaaacgcctg ttggtagcta tgatgtaaaa atcttgaagg ttgaaaaaac agcctaaaaa
    32281 cagaaaaagg agtggggagg cgatgtgctt cactcactcc tttttccatt ttgctattct
    32341 tcgaaaatct cttcaaacca cgtcagcgtc gccttgccgt atgtatggtt actgacttcg
    32401 tcagtttcat ctacaacctc aaaaccatgt tttgagc
//
LOCUS       DBEJJV010000026        28552 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.026, whole genome shotgun sequence.
ACCESSION   DBEJJV010000026 DBEJJV010000000
VERSION     DBEJJV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 28552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.026"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..448
                     /locus_tag="ACL3GT_001335"
     CDS             <1..448
                     /locus_tag="ACL3GT_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGR0516999.1"
                     /translation="RNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDE
                     KENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEK
                     VTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESK"
     gene            865..1245
                     /gene="dhaM"
                     /locus_tag="ACL3GT_001336"
                     /pseudo
     CDS             865..1245
                     /gene="dhaM"
                     /locus_tag="ACL3GT_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
     gene            1703..2416
                     /locus_tag="ACL3GT_001337"
     CDS             1703..2416
                     /locus_tag="ACL3GT_001337"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HGR0517000.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2474..2878
                     /locus_tag="ACL3GT_001338"
     CDS             2474..2878
                     /locus_tag="ACL3GT_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517001.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQ"
     gene            3214..3867
                     /locus_tag="ACL3GT_001339"
     CDS             3214..3867
                     /locus_tag="ACL3GT_001339"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HGR0517002.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3877..4341
                     /locus_tag="ACL3GT_001340"
     CDS             3877..4341
                     /locus_tag="ACL3GT_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HGR0517003.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4354..5622
                     /locus_tag="ACL3GT_001341"
     CDS             4354..5622
                     /locus_tag="ACL3GT_001341"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HGR0517004.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKFNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5636..5896
                     /locus_tag="ACL3GT_001342"
     CDS             5636..5896
                     /locus_tag="ACL3GT_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517005.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5907..7268
                     /gene="pdrM"
                     /locus_tag="ACL3GT_001343"
     CDS             5907..7268
                     /gene="pdrM"
                     /locus_tag="ACL3GT_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HGR0517006.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKC"
     gene            7422..8390
                     /locus_tag="ACL3GT_001344"
     CDS             7422..8390
                     /locus_tag="ACL3GT_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HGR0517007.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8406..9398
                     /locus_tag="ACL3GT_001345"
     CDS             8406..9398
                     /locus_tag="ACL3GT_001345"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HGR0517008.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNSVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9616..10659
                     /locus_tag="ACL3GT_001346"
     CDS             9616..10659
                     /locus_tag="ACL3GT_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HGR0517009.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGKIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10705..12408
                     /gene="lpdA"
                     /locus_tag="ACL3GT_001347"
     CDS             10705..12408
                     /gene="lpdA"
                     /locus_tag="ACL3GT_001347"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003001382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HGR0517010.1"
                     /translation="MALEVIMPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKV
                     SMELEAEEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTS
                     NDDDKSDDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTY
                     LHNAEIIENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTV
                     HKGIGTITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNE
                     VPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGM
                     TILTGTKLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCI
                     KVNEYMETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIY
                     TLPEVAAVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGV
                     HIIGPAAAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKK
                     K"
     gene            12472..13461
                     /locus_tag="ACL3GT_001348"
     CDS             12472..13461
                     /locus_tag="ACL3GT_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HGR0517011.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGIKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13534..14604)
                     /gene="xerS"
                     /locus_tag="ACL3GT_001349"
     CDS             complement(13534..14604)
                     /gene="xerS"
                     /locus_tag="ACL3GT_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HGR0517012.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(15188..16738)
                     /locus_tag="ACL3GT_001350"
     CDS             complement(15188..16738)
                     /locus_tag="ACL3GT_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005247 - voltage-gated chloride channel
                     activity [Evidence IEA];
                     GO_process: GO:0006821 - chloride transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HGR0517013.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16754..17533)
                     /locus_tag="ACL3GT_001351"
     CDS             complement(16754..17533)
                     /locus_tag="ACL3GT_001351"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HGR0517014.1"
                     /translation="MATIKEIKEFLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17520..18371)
                     /gene="ylqF"
                     /locus_tag="ACL3GT_001352"
     CDS             complement(17520..18371)
                     /gene="ylqF"
                     /locus_tag="ACL3GT_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HGR0517015.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(18625..23838)
                     /gene="zmpD"
                     /locus_tag="ACL3GT_001353"
     CDS             complement(18625..23838)
                     /gene="zmpD"
                     /locus_tag="ACL3GT_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease D"
                     /protein_id="HGR0517016.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(23882..>28552)
                     /locus_tag="ACL3GT_001354"
     CDS             complement(23882..>28552)
                     /locus_tag="ACL3GT_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005576 - extracellular region [Evidence
                     IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZmpA/ZmpB/ZmpC family metallo-endopeptidase"
                     /protein_id="HGR0517017.1"
                     /translation="IVEPEKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMSIQKKS
                     SALINMNFITDSSKVTGVGSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKSKNVYE
                     WVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYSKVNLN
                     DKLNVHGYPARKYTHLKDATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANGEVIGV
                     HQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEKEVIKK
                     LELRNISSVELYSKDGNKYRHVTSLASLPSNAENYFMKVKSENFKDVMLPVTSITNDT
                     KDNRDVYKIVASANSLIQHENNNVLENYTYYLPKTQQSETGVYTSFKNLVDAMNSNPN
                     GTFRLGATMDAREVELPDGQESYVNNVFHGILVGTNNEKYYAIYNLKKPLFGELNGAT
                     VEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHADGAIAGERSIGGLVSQVNNSTIS
                     NSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLIDKSFASIDLSSNATQGDQSIGGIV
                     GAVENSALISNSYAEGNLNNVQRFANVGGVVGNLWDPVGGLEKSGRLSNVLSDVNVTN
                     GNAIAGYNFNSIKANGTYSNKNNKVVNVVQEDDEILTKDSTVQRGEVLEDAQIKEKKA
                     TFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEKVYKNIEKLLPFYNRETIVKYGNL
                     VETSSNLYNKELLSVVPMKDKEVISDINKNKSSINKLLLYYADNTSETLNVNYQTDFS
                     NVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALNSVEYKSEAIRKVLDVSKDVSLTE
                     LYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKVIDNYVIEKIKNNKEALLLGLTYL
                     ERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNVIELGKSGYNNLLAKNNVITYNVL
                     LAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQTKAYIVEEKSTIKEVSDKQSIAGS
                     PYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFIIANISTIGFGAYDRYRSKEHPAGT
                     DLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEKLYRSVLVYDAFRFGTDEKEDKDT
                     YQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEMT
                     HNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPNDPTVTINSILKYDQSEESTRLQV
                     ADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAVAKLDTNQKYDLLRKIENEYKPDP
                     DGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIITRRGYVDEATYKRNGYYTINLFSP
                     IYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMVPYISNQYEKEAKAQGKVITSYGK
                     QIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKEREDKFGKLNKVSFIDPNGSWARQQKV
                     TIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRVLKLKKAIFKAYLDQTGDFRSSIF
                     ENKK"
BASE COUNT         8524 a         5376 c         5363 g         9289 t
ORIGIN      
        1 aagaaacaaa aatggtcaag ctgataccaa tcaaacggaa aaaccaaacg aggagaaacc
       61 tcagacagaa aaacctgagg aagataagga acatgatgaa gtaagtgagc caactcaccc
      121 tgaatctgat gaaaaagaga atcacgctgg tttaaatcct tcagcagata atctttataa
      181 accaagcact gatacggaag agacagagga agaagctgaa gatactacag atgaggctga
      241 aattcctcaa gtagagcatt ctgttattaa cgctaagata gcagatgcgg aggccttgct
      301 agaaaaagta acagattcta gtattagaca aaatgctgtg gagacattga ctggtctaaa
      361 aagtagtctt cttctcggaa cgaaagataa taacactatt tcagcagaag tagatagtct
      421 cttggcttta ttaaaggaga gtaagtaaag gtagcagcat tttctaactc ctaaaaacag
      481 gataggagaa cgggaaaacg aaaaatgaga gcagaatgtg agttctagtt ctcatttttt
      541 tcatgaaaat gtgcaaaata tagtagattg aaactagaat agtatacctc tacttctaaa
      601 acattgttag aaatcgattt gactgtcctg ttcttatttt actatatctt aacagatagt
      661 gtaaataaag ataaactatt tactggctaa ttaatcagtt aaacactagt taaggagtaa
      721 tgatgaaaaa aagaacaata ctattattga tgaccagtct gttggctctt gtcttaggag
      781 catatggttt cttggacata ttgatcctgg atcattctca tcaggattac tctttactgc
      841 tattttagaa actggggtgg tttgatggaa agtattggta ttggtcttgt tatcgtttca
      901 cattccaaac acattgcaga aggtgttgtt gaactgatta gtaaagtagc taaagatgtt
      961 ccgattactt atgtaggagg aaccgagggc ggaggaattg gaacgagttt tgattaagta
     1021 gatagggttg tttccgaaaa tacagcagat actttacttg ccttttttga cctaggttct
     1081 gctaaaatga acttaaaaat ggtgactgat ttcagtgata aaagtatcat catcaacagg
     1141 gttccaattg tagaaggtgc ctataatgca gctgctcttc ttcaggctgg tgcagaactg
     1201 tcagttattc aaacacagtt agcggagctt gaaatcaata aataaggaat tttactataa
     1261 ctctttttat aggtaagcta ttgattatct caactataaa atgttaagta aatgatttca
     1321 aaatcagaaa gggattgctt tatgcagttc ctttttattt taacaggagt gaaactatag
     1381 tgtttctaaa ttgtgaatca atcaaaactg attgtgatgg ggctattcta gctttagaaa
     1441 ccttcaaaaa ttaaaattta aggcaatcaa ttacttggaa gagtatgaaa gcatttagtt
     1501 tataggaatt ctaggtctag aattacacat atatttatga atacggggtg ctcgatagtt
     1561 agtattgttc tattctgaaa gatttgagct gtcagttgta tagaaagtgt tcgaattttt
     1621 ttaagtgatt aaattagtta attgtatgag gtgctttatg atataatgtt cttaatgaat
     1681 tttcagaaag gaaaacctca aattgttcta caaatttcta ctcttcgacc tcgaccacac
     1741 tcttcttgat tttgatgctg ctgaggatgt ggctttgacc caacttctaa aagaagaagg
     1801 agttgcggat attcaggctt ataaagatta ttacgttcct atgaacaagg ctctctggaa
     1861 agacttggag ctgaagaaaa tcagtaaaca agagctggtt aacacgcgct tttctcgttt
     1921 attttctcat tttggacagg aaaaagacgg tagttttctt gcccagcgtt accaatttta
     1981 tctcgctcag cagggacaaa cactatcggg cgctcatgat ctcttggaca gcctcattga
     2041 gcgtgattat gacttgtatg ctgcgacaaa tggcattact gccattcaga caggacgttt
     2101 ggctcaatct ggtctagcac cttatttcaa tcaagtcttt atctcagaac agttgcaaac
     2161 tcaaaagccg gatgctcttt tttatgaaaa gattggccag caaattgctg gatttagtaa
     2221 agaaaagacg ctgatgattg gagattctct aaccgccgac attcaaggtg gcaataatgc
     2281 ggggattgac actatctggt ataatcctca tcacctcgaa aatcacacac aagcccagcc
     2341 gacttacgaa gtctattctt accaagactt gctggattgt ttagataaaa atattcttga
     2401 aaagatcaca ttttaaagga gacgagctaa tgactacaaa aaagctaata ttactattga
     2461 agagtacatt gaaatgtctg aagttgattt taatgaagct gttaattatg aatttacatc
     2521 tgacacttgt caattagcaa atagtattta tcaatctctt tttaagtttt ttgataagaa
     2581 aaatttctct ggcgatttaa tttttacttg gaaatctcca tcattagtca aagaagggga
     2641 ttatattggg agaagggatt cacaagtaga taatcttaga gtaataggaa atatatttcc
     2701 gaattatctt actaatcgaa aatatagcct caatatgaat cgtaatggct gtatgggaga
     2761 ttttcctcat gacttttttg atatatacct agatcatgta gcaaaatatg cctacgaaca
     2821 aaaagttaat aatattaaag agtattatcc tttaaaaaga gcgattttac accaatagaa
     2881 tgcattgtat tttcgatttt tttctaattt tgacgacttt ttagaaaaaa attatttaaa
     2941 gactatatgg caagtttcta aagaaactcc tttttctgaa atggatttta atatgtttaa
     3001 aaatatttca gaaaagataa tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag
     3061 taattataaa aaatagccag tctttataaa ctgtattcac gtattcaaat cgtatatata
     3121 gtcgatttat taaatcttta gataaactgt aaaaagtggt ttccatagcc actttttgct
     3181 ataatagagg cagtaaaaat gaaggagtcg gctatggaac actcgtcttg gcatgctttg
     3241 attaaggcgc aattacctga gggttatttc gggaaaatca atcagtttat ggagcaggtc
     3301 tattctcagg ggattattta tccacccaag gaaaaggttt ttcaggctct cttgacaaca
     3361 ctgcttgaag aagttaaggt ggtaattcta gggcaagacc cctatcacgg accaggtcaa
     3421 gcgcagggct tgagtttttc tgtacctgac tctatcccag ctccaccatc cttgcaaaat
     3481 atcttgaaag aattgtcaga tgatatcgga gttaagaaat ctcatgattt gacagcttgg
     3541 gctgagcaag gagtcttgct tcttaatgct tgtttgactg ttcctgctgg acaggccaat
     3601 ggtcatgctg gtcaaatctg ggagcctttt actgatgctg tgattcaggt ggtcaatcat
     3661 ctagatagac cagtcgtttt tgtactctgg ggagcttatg cacgtaagaa gaaggcatta
     3721 gttaccaatc ctcatcactt gattatcgaa tcagcccatc caagtccttt gtcggtttat
     3781 agaggatttt ggggttccaa gcccttttcc aaggccaatg cattcttaaa agagacagga
     3841 caagagccaa tcgattggct tagataagga gaaaatatgc ctcagttagc gacgatttgc
     3901 tacattgata atgggaaaga actgctcatg ctccatcgta ataagaaacc caatgatgtc
     3961 catgaaggga aatggattgg tgtgggtggt aagctagaga gaggagagac gccccaggaa
     4021 tgcgcggcgc gtgaaatcct tgaagaaaca gggctcaaag ccaagccagt tctaaaaggt
     4081 gtcatcactt ttcctgaatt tacaccagat ttagactggt acacctatgt ttttaaggtg
     4141 acggagtttg agggcgactt gattgactgc aatgagggga cgctagaatg ggttccctat
     4201 gatgaggttt tgagcaagcc gacttgggaa ggtgaccaca cctttgttga gtggctttta
     4261 gaggataaac ccttcttttc agccaagttt gtttatgatg gggataaatt gttggatacc
     4321 caagttgatt tctatgaata aaggagaaag cagatgctac taatcaaaaa tggtcgtgta
     4381 atggatccca agtctggttt ggatcaagtt tgtgatgtct tagttcaaga tgggaaaatt
     4441 atcaaaattg cgcctgagat cacggaagaa ggagcagaaa cgattgatgc tactggtctt
     4501 gtggttgctc ctggtttggt cgatattcat gtgcatttcc gtgaacctgg tcaaacacat
     4561 aaagaagaca ttcatactgg tgccctggca gccgctgcag gtggttttac tactgtcgtc
     4621 atgatggcta ataccagtcc aaccatttca gacgtggaga ctttgcaagc agttctccag
     4681 tcagctgcca aagagaagat taatgtcaag acagttgcga ccattactaa aaactttaat
     4741 ggtaaaaact tgactgactt taaggcgctc ttagaagctg gtgcggctgg tttctctgat
     4801 gacggtattc cgcttgagag cagtaagatt gtcaaggaag ccatggagga agccaaaaaa
     4861 ttcaatacct ttatcagcct tcatgaggaa gatccaggtt tgaacggtgt tcttggcttt
     4921 aatgaaaata ttgctagaga acatttccat atctgcggtg ctactggagt ggctgagtac
     4981 gctatgatgg cgcgtgatgt catgattgcc tatgcaacta aagcccatgt tcacatccag
     5041 catttgtcta aggaagaaag tgttaaagta gtggagtttg ctcaggggtt aggtgcagaa
     5101 gtcacagcag aagtagcgcc acagcatttc tctaagacag aagcacttct tttaacacaa
     5161 ggtagcaatg ctaagatgaa tccaccgctt cgtttggaat cagaccgtcg tgccgttatc
     5221 gaaggtctca aatcaggtgt catcacagtt attgcgactg accacgcgcc tcatcatgta
     5281 gatgaaaaaa atgttgagga tattaccaaa gcgccatctg gtatgactgg cttagaaaca
     5341 tccctgtctc tcagcttgac ctatttagta gaagctggtg agttgagctt gatggaatta
     5401 cttgaaaaaa tgacatacaa cccagccaag ctttacaact ttgaagcagg ttacttggct
     5461 gagaatggtc cagcagatat cactattttt gatgccaagg ctgaccgctt tgtggactcc
     5521 cattttgctt ccaaagcagc taattcacca ttcatcggtg aaaccttaaa agggcaggtt
     5581 aaatatacca tctgtaaggg acaaatcgtc tatcaagctt gataggagtt agaatatgaa
     5641 ttattttcga aaacgtaggg agagacaagc gaaatctaat agtggaattt actgtcccgc
     5701 agctaatcgt tccaaaattc aatatgaaac taaagaaaaa gctgaccatg cggttcaata
     5761 tgataacgga ggtttagtta gaagctatta ttgtcgtaca tgtgcgtgtt ggcatactac
     5821 ttcaaaatct aataaacctc cgctaagttt gaaaaactat ggtctgaaac tctttggttt
     5881 agataaatca gaatagaaag agaagtatgt ataagacaaa gtgtttacga gagaagttag
     5941 tattattttt aaaaattttc ttcccaatcc tgatctacca atttgccaat tattctgcct
     6001 cttttgttga tactgcaatg acaggtcaat acaacactat ggacttggct ggtgtatcta
     6061 tggcaaccag tatctggaat cctttcttta catttctaac agggattgtg tcagccttgg
     6121 tgcctatcat tggtcaccat cttggtcgag gcaaaaagga agaagttgcg tctgattttt
     6181 accaatttat ttatttggcc ttgggcctat ctgtggtctt gctggggatg gtacttttct
     6241 tggcaccaat aatcttgaat catattgggt tagaagcagc agtagcggca gtagcggttc
     6301 gctatctttg gtttttatct atcgggatta tccccttgtt gctctttagc gtcattcgtt
     6361 ccttgctgga ttcgctgggc ttgaccaaac tgtccatgta cctcatgctt ttgttactcc
     6421 ctctcaatag cggatttaac tatctcttga tttacggtgc ctttggtgtt ccagaactgg
     6481 gaggggctgg tgctggttta ggaacatcct tggcctactg ggtcttgctt gggatttctg
     6541 ttctggtttt atttaaacag gagaagctca aagccttaca ccttgagaaa cgaattccac
     6601 ttaatatgga taacattaag gaaggagttc gtttaggtct gcctattggg ggaactgtct
     6661 tcgcggaagt ggctatcttt tcagtggttg gcttgattat ggctaagttt tcgtccttga
     6721 ttatagctag tcaccagtca gctatgaact tttcaagtct tatgtacgcc tttcctatga
     6781 gtatctcatc ggctatggct attgtcgttt cctatgaagt gggagccaag cgatttgatg
     6841 atgcgaaaac ctatattggt ctaggaagat ggactgctct catttttgcg gccttcacct
     6901 taaccttcct ttacattttt aggggaaatg tggccagtct ttatggtaac gacccaaaat
     6961 ttatcgattt gacagtgcgt tttttaactt atagtctttt cttccagtta gcagatacct
     7021 ttgcggcgcc gcttcaggga attttgcggg ggtataagga tacagttatt cctttttacc
     7081 ttggtttgct tggttattgg ggcgtagcaa tccctgtggc tacgctattt gattccctaa
     7141 cagattttgg agcttattct tactggatcg gcttgattat tagtttgatt gtgagcgggg
     7201 cgctctaccg ttggcgttta actgtgatta tgaagagatt tgaatcttta gcaaaatcca
     7261 aatgctaaaa agtttgtgaa aaaatattct tgacaagaaa atcccttgtt ttcacggggt
     7321 tttctttttt attttgtgaa atttctttta gaaaaacttt gacagtattt gccaaaagcg
     7381 gtaaaatagt aaggtaagaa gaaagttaga aaggcaagaa gatgtcaact ttagataaaa
     7441 atcttttgct agaaatgttc cgtaagatgg aagaaatccg tcgcatggac ttaaaaattg
     7501 cacaattagt aaagaaaggg aaagtgccag gaatgacgca cttttctgtt ggtgaagagg
     7561 cagctaacgt gggggctatg ttagctctca atccagatga tctgattacc tcaaaccacc
     7621 gtggacacgg gcaagctatt gctaaaggga ttgacctcaa cggaatgatg gctgaaatcc
     7681 ttggtaaata cactggaacc tgtaaaggga aaggtggatc tatgcatatc gctgaccttg
     7741 atgctgggaa ccttggtgcc aatggtatcg taggtggtgg tatggggatc gctgtcggtg
     7801 cagccctcag tcagcaaatg caaaataccg gtaaaatcgt tgtctgcttc tttggagatg
     7861 gtgcgaccaa tgaaggtgtt ttccacgaag cagtgaacat ggcttctatc tggaacctgc
     7921 cagtcatttt ctattgcatt aacaacggtt acggtatctc tgcggatatc aagaaaatga
     7981 ccaatataga acatatccat caacgtagcg ccgcttatgg aattcctgga atgttcatcg
     8041 aagacggtaa caatgtcatc gatgtctatg aaggatttca gaaagctgtg gaccatgttc
     8101 gcagtggcaa tggtccagtc ttgattgaaa gtgtaactta tcgctggctc ggtcactcat
     8161 catctgaccc tggtaaatat cgtacgcgtg aagaagtgga attgtggaaa caaaaagatc
     8221 caatcgaaaa cctccgcaat taccttattg aaaataacat tgcaagtgcc gaagaattgg
     8281 aagaaatcca agcgcaagta aaggaagcag tagaagcttc tgttaaattt gcagaggaaa
     8341 gcccattccc accgcttgaa tcagcctttg aagatattta cgcagactaa ggagaaagag
     8401 ataaaatgga aacaaaaaca atgtccttcc gtgacaccat tatccttgct atgtctgagg
     8461 aaatgcgtcg cgatgaaaat gtgttcttga tgggagaaga cgtcggtgtc ttcggaggag
     8521 acttcggtac ttctgttgga atgcttgaag aatttggtcc agaacgtgtc cgtgactgtc
     8581 cgatttctga agctgccatc tctggagcag cagcaggagc agccatgaca ggacttcgtc
     8641 caatcgtcga tatgaccttc atggacttct ctgttattgc catggacaat atcgtcaacc
     8701 aagctgctaa aacacgttac atgtttggtg gtaaaggtca ggttccaatg actgttcgtt
     8761 gtgcagctgg taacggagtt ggctctgccg cccagcactc acaatctcta gagtcttggt
     8821 ttactcacat tccaggactt aaggttgtgg cacctggaac acctgcggac atgaaaggcc
     8881 tgcttaagtc ttctatccgt gataacaact cagttattat acttgagtac aagtcagaat
     8941 ttaaccaaaa aggggaagtg ccagttgatc cagactacac aattccactt ggggttggtg
     9001 aaatcaaacg ccaaggaacg gatgtaacag ttgttactta tggaaaaatg cttcgccgtg
     9061 tggttcaagc tgctgaagaa ttagcagaag aaggaatttc agttgaaatt gttgacccac
     9121 gtacccttgt tccgcttgat aaggatatca tcataaactc agtgaagaaa actggtaagg
     9181 ttgttctggt caacgatgcc cacaaaacaa gcggctatat cggtgaaatt tcagctatta
     9241 tttcagaatc agaagcattt gactatctag atgcaccaat ccgccgttgt gcaggagaag
     9301 atgtgccgat gccttatgca caaaacctag aaaatgcaat gattccaaca gttgaaagta
     9361 tcaaagatgc aatccgaaaa acttataaca aagaataggg ttacataaga taagttatgt
     9421 aaataaaata aagctgacga gaaactttgt atcttttagg tgcagagctc ttcgtcatta
     9481 atatcttaga ttagagcacg ggctaaaaga tcggaaaaaa gataaatctc cttggcttca
     9541 tcgaagccat cgtcgatttc ctatttttca gtcgcttttg acgccctttg tatcataaat
     9601 agaattggag aggtcatggc tgatgacaag ctaagagcga ctcctgcagc tagaaagtta
     9661 gcggatgatt tagggataaa cctctacgac gtttctggct caggtgcaaa cggtcgtgtc
     9721 cacaaagaag acgtggaaac ttataaagac acaaacgtgg ttcgcatttc gccacttgca
     9781 aaacgaattg ccctcgaaca taacattgct tggcaggaaa tccaaggaac cggtcatcgt
     9841 ggtaaaatca tgaagaagga tgttttggcc ctgcttcctg aaaatatcga aaacgatagc
     9901 atcaaatctc ctgctcagat tgaaaaagtg gaagaagtcc ctgataacgt aacaccatat
     9961 ggtaaaatcg agcgtattcc aatgacacca atgcgtaagg ttattgccca acgcatggtt
    10021 gaatcttact tgactgcgcc aaccttcacc ctcaactatg aagttgatat gactgaaatg
    10081 ttggctcttc gtaagaaggt tcttgagcca atcatggaag caactgggaa gaagactact
    10141 gtaacagacc ttctttcgct tgcagttgtt aagactctta tgaaacaccc atacatcaac
    10201 gcttcattga cagaagatgg caagactatt atcactcaca actatgtcaa tcttgccatg
    10261 gcagttggga tggataatgg attgatgaca cctgttgttt acaatgctga gaagatgagt
    10321 ctttcagaac tggttgtagc ctttaaggat gttattggcc gtaccttgga tggtaaattg
    10381 gctccaagtg agttacaaaa ttcaacattc acaatcagta atttgggaat gtttggtgtt
    10441 cagtcctttg gtccgattat taaccaaccc aactcagcta tccttggtgt cagttcgaca
    10501 atcgagaagc cagttgtcgt caatggtgaa attgtgattc gcccaatcat gagtttagga
    10561 ttaaccattg accaccgtgt cgtagatggt atggctggtg ctaagtttat gaaggacttg
    10621 aaagagttga ttgaaacgcc aatctcaatg ttaatttaag agcaagagta ttcattttta
    10681 agatatagat aaaggaagga agacatggcc ttagaagtaa ttatgccaaa agccggcgtg
    10741 gatatgacag aaggacaaat cgtccaatgg aataaaaaag tcggagaatt tgtaaaagaa
    10801 ggagaaatcc ttttggaaat catgactgat aaagtcagca tggaattgga agccgaagaa
    10861 gatgggtact tgattgccat tctcaaagga gatggtgaaa ctgtccctgt aacggaagtt
    10921 atcggttacc ttggtgaaga aagggaaaac atcccaacag ctggagcagc atcgccagaa
    10981 gctagctctg tacctgtagc aagtacctca aacgatgatg ataagagcga tgatgctttt
    11041 gatatcgttg tgattggtgg aggtcctgct ggttatgttg cagccattaa agctgcccaa
    11101 ttcggcggta aggttgccct tgttgagaaa tctgaacttg gtggaacctg cttaaaccgt
    11161 ggatgtattc caaccaagac ctaccttcat aacgctgaaa ttattgaaaa tatcggtcat
    11221 gctgcaaatc gtggtatcgt gattgaaaat cctaacttca ctgttgatat ggaaaaactt
    11281 ttagaaacta aatctaaagt tgttaatact cttgttggtg gtgttgcagg acttcttcgt
    11341 agctacggag ttactgttca taaaggaatt ggtacaatca ctaaagacaa gaacgtcttg
    11401 gtaaatggtt ctgaattgct tgaaaccaag aaaatcattc ttgctggtgg ttcaaaagtc
    11461 agcaagatca acgtccctgg tatggaatct ccacttgtca tgactagtga tgacattctt
    11521 gaaatgaacg aagtgccaga aagccttgtt atcatcggtg gtggagttgt cggtatcgaa
    11581 ctcggtcagg ccttcatgac atttggttca aaagtgactg ttatcgaaat gatggaccgt
    11641 atagttccag ctatggatgt ggaagtttct aagaaccttc gcttgattct tgagcgtaaa
    11701 ggaatgacca tcttgactgg tactaaactg caagaaatca ttgaggaaaa tggtcaactt
    11761 cgtatcaagg ttgaaggaaa agacgatatc atcgcaagca aagctcttct ttcaattggt
    11821 cgtatgccag accttgaagg tattggagag gttgagtttg aattggatcg tggttgtatc
    11881 aaggtcaacg aatacatgga aacttcagtt ccaggcattt atgcaccagg tgacatcaac
    11941 ggtactaaga tgttggctca cgcagctttc cgcatgggtg aagtttccgc tgaaaatgcc
    12001 cttaaaggaa atcatgcagt tgccaaattg aatttgactc ctgcagccat ctacactctc
    12061 cctgaagtag cagcagtagg tttgacagaa gaacaagccc gtgagaaata cgatgttgcc
    12121 atcggtaagt ttaactttgc tgctaacggt cgtgctattg catctgacgc agctcaaggt
    12181 ttcgtaaaag ttatcgctga taagaaatac ggagaaatcc ttggtgtaca cattattggt
    12241 cctgcagccg cagaattaat aaacgaagca tcaagcatca tcgaaatgga aatcactgtt
    12301 gaggaaatgc tgaagaccat ccacgggcac ccaacttact ctgaagtgat gtacgaagcg
    12361 tttgcagatg ttctaggaat ggccatccat tcacctaaga aaaaataaaa cgaagataga
    12421 ttagactgga aggttatttc cagtttctat catataaagt aaagggatat catgaaatac
    12481 attatcaatc attcaaatga cactgctttt aatattgcct tggaagaata cgcctttaaa
    12541 caccttttgg atgaggatca aatcttccta ctttggatta acaagccatc tatcattgtt
    12601 ggtcgtcacc agaacactat cgaagaaatc aaccgtgatt atgttcgcga aaatggtatt
    12661 gaggtagttc gccgtattag tggtggtgga gctgtttacc acgatttaaa taacctcaac
    12721 tacacgatca tctccaaaga agatgaaaat aaggcatttg acttcaagag cttctcaact
    12781 ccggttatca ataccctggc tcaacttggg gttaaagctg agttcacagg tcgtaatgac
    12841 cttgagattg atggtaagaa gttctgtggc aatgcccaag cctatatcaa cggccgtatc
    12901 atgcaccacg gttgcttgct ctttgacgtt gatttgtcag tcctcgcaaa tgcccttaag
    12961 gtttcaaaag ataaatttga atcaaaaggt gtgaaatccg tccgtgcccg tgtaaccaat
    13021 attatcaatg aattaccaaa aaaaatcaca gtcgaaaaat tccgtgattt actcttggaa
    13081 tacatgaaaa aagagtaccc agagatgact gaatacgtct tttcagaaga agaattggcc
    13141 gaaatcaatc gcatcaagga tactaagttt ggaacttggg actggaacta tggtaaatca
    13201 cctgaattta acgtccgtcg tggaatcaaa ttcactagtg gtaaggttga agtctttgct
    13261 aacgttactg aatcaaaaat ccaagacatc aagatttatg gtgacttctt tggtattgaa
    13321 gacgttgctg cagtagaaga tgtccttcgt ggggtgaaat acgaacgcga agatgttctt
    13381 aaggcgctaa aaaccattga tatcacacgc tacttcgctg gtattagccg tgaagaaatc
    13441 gctgaagcgg tagttggata aatcaaaaag aagttggcca actaaccaac ttcttttttt
    13501 gatatttatt tacataattt aaaatacgta aaatcataaa ctatccagag cattcttttg
    13561 ttcatcatta acaatatggg tatagaggtc agtgacttgt gtgctggcat gtcctagttg
    13621 gtgactgact aaaacttgtg atttagtagc atcatagagc ctagttgcta gtgtatggcg
    13681 cagtttatgg ggtgttacac gtactttaaa atcctctgag tatttagcaa ccattttctc
    13741 aacgctagaa gcatcgatac gattaggaac acctctgtag agagttaaaa aaagggctgt
    13801 atctgttttt tccgttttat agcgttgatt ccgaatggcc agataattct ctaaataagg
    13861 tttagcaaaa gcagcgacat tgactgagtc acgtttgcca ccttttcgag taacatcaat
    13921 aaccatcatt tttagattga gatctcttag atctagatta acagcttcag ataagcgaac
    13981 accagatgcc aagagaaggg caataatggc taaatctcgt tctttatttt tgttgaatga
    14041 tgagagagct cgatttgaaa gctgttgtgg gtgctcttga tcgatataag ttagaaaacc
    14101 ttctgtttca tcacctagaa agagtttttg cttgatattt tcagctctgg cagcaagggt
    14161 ttctttcttt ttcttggttg aaactttttt cattacatta cgatagaaat aaggttcccc
    14221 ctgatcgttt tcaacctcct cggttagata cttgtaaaga ctagaaagtg ctgataaggt
    14281 tcgattgata gttgtctgtg aaacaccttg ttttgttgta ttagcattca gcaagggacg
    14341 ttcacgtaga taaaggataa aggattccat gtctttctta gacatatttt ccaaaactga
    14401 taaaggaata tcggatattt tatcagcgtt tgaaatacca gactccaaaa cccagctgaa
    14461 aaatcggtca tattccttaa ggtattcgta cagggttgta aaactgtagg gcacagccag
    14521 tttagattgg tagtattcca gaacatacca gggcatgagt tgttttagtt tgtcgattcg
    14581 ttccagtaaa atctcacgtt tcatgtattt tctccataat taagtatact agtagtatag
    14641 catagacttg tatatttttc aagaaaatta tagtttttca gaaagatgct ataggagttt
    14701 ttcaaagtga taaaaagact tagacctaca aacaaaacag aataaggaaa ataataaaaa
    14761 tctcacccac taaacttctg ttaatactac ataactgaag agctatataa ggagctatga
    14821 gatacaaaac acattgtata atagattgaa actagaatag tacatctgga cttctaaaac
    14881 attgctagaa attgatttga ttgtcctgat tgttttatcc tatttctatt tcatttctct
    14941 atataattgc tattgttttc tttttcatga ttttaatctt actgtacaga tttgatacag
    15001 taaactcctt tctagcttta tactttatca tttctaactt aattatagtc ttatttttaa
    15061 taaagttcaa ttatttatat gtaaaattcc tcatcagtaa aaaataaccg atctcatttc
    15121 tgagaatcgg ttttctaaat aaatcaaact gatcatttac ataacataaa ttatgtaaat
    15181 gatcatacta caacaacaaa tctttgactt ttccaatttc actttttgga ataaccaggt
    15241 gaatcatatc acccagatac attctggttg agccgttaac tgtttggctc ttgccattat
    15301 ggacttgagt tgtgatgagg acgttgtgtg gtaagttgag ttcatgaact tgtttcccag
    15361 caattttatc agaaactggt atttcgataa gtgtaacttc tccttcgcta gatacttctt
    15421 ctggaagcat tttttccagc atggcttcat agactggcgt acctttgagc aaatccatga
    15481 taatataaga aacaagagtg acaagaccaa gtggcataag gttgcgaata tctcctacca
    15541 tctcagttac gaggatcata gcggttaagg gagcttttga tatggctcca aaatagccac
    15601 tcattcctag aatgacaaat atagggaatt gctcttgact gacaagtcca agattgacac
    15661 agataacacc aactaaggca ccaagcaaag aaccaagagc taaaatgggg aggaaaattc
    15721 ctcctggcag tccacttcca tagctaatca tactccaaat aaagcggatt aaaaagtaag
    15781 ctaataaaac ttggaaacta aaattttgtt cagttaaaga aaggacaagc tgatttccgc
    15841 caccaatgat ttgaggtaag aagattccga ctggtatgat aaggataaaa gccaagatgg
    15901 gataataagc cctatccaaa tggatttttt gaccaatcaa gtcataaact cttccaacgt
    15961 ttaatacagc tttctcatag agaaaacctg aaaatccaag gaaaattccc atgacgagat
    16021 atatccaata ctgatctagg gtcatgggag gaatgttatc tggcatatcc aatactggtg
    16081 tcaaaccgaa catgagtaga gacacaaagt ttgctacgat gctggctgct agagttgaga
    16141 cccagaaaaa gcgcgaaaaa tggtgataga cttcttctac aacaaagaga agtgctgcaa
    16201 taggagcatt aaaggctgcg gctaaacctg ctgcagctcc actggcaatc aaggaacgtt
    16261 cctctactgg actggatttg agccacttgg caattccttt accaccaact gctccaagtt
    16321 gaatactggg tccctctcga cccagcatga gtccactggc aatagcaaga atacctagca
    16381 catatttttt ccaaagaatg ccccaccagt tgagggacat gaggcctttc agttcggctt
    16441 cgacttgagg aattcctgag cctttaatat ctttttctga ccgtgttagt ttggcactga
    16501 gccaacagat gagtatataa aacaaaacca gtacaaaaag attgcgcact aagtaccctt
    16561 gatcttgata aactccttgt atcaggtgga agcccttttc aattaagaaa cgaaaggatc
    16621 cgacgataat tccaacgatg aggccgacaa tgattcctcg accaacttgg gatagtatag
    16681 tgctggatgc aaaggcgaat tctttcttag aacggactat ttccgactgt tcctccatgg
    16741 tatttccttt caattaactt tcttttttac ctaaaaccag tgatttaacg ggttcaaagc
    16801 tggttcggtg aattggggta actcctagtt ttgtgaggcc ttccagatgt ttagctgtgc
    16861 catatcctgc attagtagcg aaatcatagc cagggaactg ctgatcgtat tccttcatca
    16921 attcatcacg tgttaccttg gctactatag atgctgctgc gatagagagg gagttggcat
    16981 ctcctttgat aatggaggtt tgtgaaatgg gcaagtccag tttcatggca tcaatcaaaa
    17041 ggtgctctgg ttgagggctg agctgggaga ttgcttcttg catggctagt ttggttgctt
    17101 catagatgtt gacttggtcg atgacctgat tatctatgat accaattcca atcgacaagg
    17161 cttggtcttg aacggcttgg aaaatctcca gatgtttctt tttaggaatt ttcttgctgt
    17221 cgttgagacc tttaatctta caatttttag gtaaaatgac ggccgcagcg actacaggac
    17281 cagcaagagg accacgacca acctcatcaa tacctacaat taaggtcaat ccttgcttat
    17341 aaagttcttt ttcataagaa agcatggatt ccaagcgcaa attttcatct aattcagctt
    17401 gaatggctct tttacgcttg ctgatttcct tttgaactcc tgagcgatta tccttttcaa
    17461 gctctaaaaa aatagggctt tctaactcct tgactgtcac aaggaattct ttgatttctt
    17521 taatcgttgc catcgaggtc ttccaatgta tctaaggtat agttaccgag tttgccatca
    17581 cggacttcct tcacgaagag actgtaaaaa cggtcatagt catcacggaa accgagggcg
    17641 cgggtcatat ccataataat cacaggcgct tcttcttcaa ttttcatttg tttgaagcgt
    17701 tcagccagct tttctggata atgttctttg aaataattga taccaaaaat ggtaacctca
    17761 tccataggaa gcaactgatc cttgatagct ccagtcaatg ccaacttaag tgcaacagtt
    17821 tcatcctcaa acttaggcca gagaatcccc ggtgtatcca agatttccag gtctttattg
    17881 gttttaagcc attgttgacc ttttgtgacc cctggcttgt ttccaacaac agcaatcttt
    17941 ttaccagcca aacggttcat cagagttgat ttaccagcgt ttggaatccc gataatcata
    18001 gtacgcaagg tttcaatctg aatcccacgt tctttctggc gagcaatctt atcagccatg
    18061 agcttcttgg ccgcatctgt tacaactttt acagtcactt gctccttgga gttgatagcc
    18121 agagtttgga ttccttgtga ttcaaaatac tgacgccatt ccttggtcat tgctggatca
    18181 gccaaatccg ccttatttaa aatcaagagt tttggtttat caccaacaat cttggtcaac
    18241 ataggatttt gactagatag aggtaagcgt gcatccacca aaatcgttac aaaatcaaca
    18301 aattttaaat tttcctgcac ctgtcgacgc gctttagaca tgtgaccagg aaaccattga
    18361 atagtagcca ttgagttttt ttcctttcgt agcaagggtt tagagatcct attttatttt
    18421 actatcgttt gaacataaag ggttctcaaa tgaatgatgt tcaaacagtt ttttgtttta
    18481 tggcatagaa atctacctta tattatatca tgccttcttt attttgtccg atgatagcct
    18541 ttcaagtacc ctatatagaa aaaagccatc aaatgatgac ttttcagagg gagcaaaaaa
    18601 ctgttccttc tatattctaa acatttaaat gtcttcttta aacagtttat taaagaaacc
    18661 gtctgtgttt ttaagaaggg ctttgaagac cttagattta agagcaacag tgtgagagaa
    18721 gtcatctggt ttcttcaaat cttcttcaac tgctttatca aataaaggcc ttaactcatc
    18781 atagttactg atatggacgc catcaatatc gatagcctca aaacctttct tagctttagc
    18841 aagaacttcc ccgtaccaat gtctcttcca ctcttcaaga gtattaaagt ttcctttcga
    18901 tactttatta attattagct tatcgcttag taaaccgtgg ttgtttttat ctgcttctgc
    18961 tttgtattta tttgatacat aactaataaa gccattttca taaccataat agccccacat
    19021 acggaaagca ttgtgcttaa atgataatga accaggagca ccttgactcg tattcccacc
    19081 gtaaattcct gccatcatat tgacatttac gtaagctgag tttggtgtaa aatcttctgg
    19141 tctataacgt ccattacctg gatttccatg ttttgtcatg aagttattat ccactaaatc
    19201 attgacgcta gataaagtca ttaccttttc ttcatctttc aaatcacgga tactatccca
    19261 ttggtttgga cctaaaagat cattatactg aatcttagag cgcatttctt tgtcaatctt
    19321 cttgaaccac ttactattgt ctcctttaat tttaggaagt acagcatcag cttctacatg
    19381 atcaagcaac atcatagctt cattgtagtt tctcatgtag cggtcaatgt catcacgtgt
    19441 ctttaatttg tcaggatctg ggttgtacca ttggttacca tcatttggac gatggtaagc
    19501 catgttaatt ccaagtgcgc cgtattcacc attagtcgtt gagctgtcag gtgtttgcaa
    19561 cataccttga gcataggctt caacgtctgt accttgacga tgcttatgac caccgaagta
    19621 aagcattcta tcgtttacgt gtgttgtttc gtgagtaaag gctgaaatac caaatgggct
    19681 aatcatatcc gtcaccataa acaagacctt gtcatcatta tttggattag ggaatattga
    19741 tgccatagcg cccatacgcc agtctctatc atggtgtcgc catgttggac catataattc
    19801 acgaattgga gctatagggt tacctttact gtcaaatcct cgacgaccta caggagaacc
    19861 attgtaggtc tggttatccc aaactggtgt cggtaccata ttttgactct taagaagtct
    19921 atcacgaaca ttaggcagag ctaatctgga ccagaaatct aaataagttt gttgagcatg
    19981 tgcaacttca tcaatcttag ttttgaactc attacgagct tcttctgtat gttttccata
    20041 tttctcaaat gaactgtacg ccatcgtgtt atatgttgaa attaagaaca tatgggcatc
    20101 tttaagcgtt agaagtggta aaatcatacg accatgaaca ccgttatcta aaccatcgaa
    20161 cacacgatga cgtttatctt tcaactctgt atttgttgtc ttaggttctg aaacataaac
    20221 attcttagct gagtggataa accaatcatt gatgtcttta tcctctgtaa acagacgcat
    20281 gttgtattct aagaagttac gcaaattact tttaccagta ttacctgcga tgatttcacg
    20341 gtaagcatcc tgagtccgat cccctttcaa gttcttttca cttgaaccga tgttgatgag
    20401 tctgtcaata acacttggtg ttttaccata aaaatcaggt ttgaacatca tgatgttttt
    20461 tatacttatg tcaccgtatt tgatatcata gtaacgattg agataagtca gagccatcat
    20521 gattttagct ttattggttt ccactttctt gagaagtgat tttatcgcag cttcatcacc
    20581 attcaattga tggtcttcat tttcgaccaa ggatttgact aacttatcta gattttgctt
    20641 cacttcggca aagctttctt ctaagtatag atctttaata taaccattct tacgttcatc
    20701 cgtattctct gcaggtttat cacgtctact cattaaatct cttacttctt gtgaaatcaa
    20761 ttccacactt gataattgag atttaacatc agcaatcaat ttatcacgat ttttaacaac
    20821 catattcggt gtataaacaa catcaccaag accagataca ctatattcac gcacttgttg
    20881 gactttagaa tcagtattct tagtaacatc catttcttcc ttagtaccat cagcatagtg
    20941 aaccataatc ttatcaatat ctgataaatc ggtcacgaat tgaccatcct tcatccccgt
    21001 aacagaaagg acttctttct tagctaagtt tgaatcttct gcaagtttgt taccttggtt
    21061 gacaatccat tctttattat aaaatggttg aagtttctca atattacgat aagctaaatc
    21121 acgttcggat ttgtagtctt gagttgactt atattcatct tctcttctgg ttaaacgatt
    21181 taagcgattg accacaggtt cgttgatttc gtatttatca gcagtaagtc caaaatttgc
    21241 aattctctta ttagcttcat cttgactaat ttctttaatt ttgtcacgag aacgtttgta
    21301 tgaatgctta cctgaactga cacctttgac aacaaagtta cgctctaacc agccatttgt
    21361 gaaataacca ccatcgtagt ccaaatcgga agaaccaaag aactcttcac cattttcaac
    21421 tctcatcatt gaaatattat cttcaagttt accaaaagga agattgctat tgataaatcc
    21481 acctgtttca aacaaaactt tagtcttaat ggttcctttg gtgactgatt tacgaattga
    21541 accgtattta ccaattccca tagagtcgtt accattatct gttttagcaa ctaaaccacc
    21601 tatacgggct ctgttagcaa caatatcagc ctcgacatat gcttttgcaa gattacctct
    21661 ccaaatctca ccggcaatgc cagccatata ttgaccttta tcaccaacac ctgtaagatt
    21721 accgatgaag gctacatttg tcaactgacc accactatcg attttattga cgatacccgc
    21781 aatattgtta ttagcaacta cattaccagt taccttaaca tcttcaacag ttgcattttt
    21841 caccatattg gcaacaggtg ctattccgtc agcccaaggc atattgatat ccacattacc
    21901 taaattaata tttttcacag aaccattttc aacacggtca aataagggac gggcaatgtt
    21961 atgaattgta tattgtttac catcaacact tgatagatgt cccttaaacg tacctggaac
    22021 atattgtttg ttaggtgttg gtacattcgt tgcattcaaa tctgctccga ttttaaatgt
    22081 accattttta tcagcattca tggcatctac taactcttta aagttataat aaacgtcatc
    22141 aacttttgga actggttttt caatataatg aacatacttg ttacgaacct tcgttgggtc
    22201 tgtatgttga atcaaatctt gagcttcggc agtgatttta taaagtttct taccttcttc
    22261 agtcacttct tcaattttat caactgctaa acgtgttact ttattatcac gactagtaat
    22321 ttttaagtac attttcttca catcttcatc tgaaggtttt tcagtcataa aatcactagg
    22381 tgtttcagta ccatcgtcat ttaccttcac taaattagta gatgcgatat ttttaatttc
    22441 aacttttttc aaatccaagc gaagtggttt ctcttctaat gttgcagttt cttctccctt
    22501 gccacggtca taggtcatag tggtctctat cttatagtcc ttgtagaatt ttaaatcttc
    22561 tacctgctta tctaattgct ctgaagtcaa atctactgtt ttgacaattt catttccatc
    22621 tttaattgtc gcagtaattt tattgattgt gactccatct gtattaacta aatgataaga
    22681 aagagttgcg gatcggttta atacatttgt atttgttcta tctaaggtca aaacaggagc
    22741 cgttttttct ttaggttttt ctttggtacc ttttacaaga attttaggct tcatttcttt
    22801 caaaatagtt actgtttcaa ctgggtcact gatttttttg ccatgtaact cttcatagct
    22861 agtaacaatt tgacgttcgc catcctcacc aacttgtcta acagaatcat cgcctataaa
    22921 tttgctagga tcagattctt ctatagtggt tttaggaata gtctctgtcc gaatatcggt
    22981 atgtaaagaa ggcaactctt ctctttctga tgcaacttct gaaactgtag atattggttc
    23041 agtatactct ggaatgtcgc taacaggtgg ctcaatcaag tttccatttt catccactcc
    23101 tgttgtacct actggctcag tatattctgg gatgtcgtta acaggtggtt caatcaagtt
    23161 tccattttca tctactcctg ttgtccctac tggttcagtg tatgctagtt tctcatgaac
    23221 ttcaggctca acaaggtttg cacctattgg ttgcgtatag tcaggcttct catgaacttc
    23281 cggttcgcct ttctctgtta caactttggg ttgctcaact ggcgaaacag ttgatgctgg
    23341 agaaaccgac gaaacagttt tatcatcaag ctccaagtaa ccaacatatc tgtaaccaga
    23401 aatttgcaac acaccatcac gtccagactc atggatgtta gcattcaaat taagtgctga
    23461 agcagttgat agtgtaacta aacctgtcgc ccctacaatc aaaaatgtag ctattttttt
    23521 atttctatta tcttttgtga taatcacaat aagactcccg atagctaaca aacccaatgc
    23581 agtcataata gattgagaac ttcctgtgtt tggtagtgcg tctttttcat aatccaaagc
    23641 atatgactct ttggattcat caggtctacc ttgtttgagt tgatcacgtt cagtttgtgt
    23701 caaactacta taatctaagt aatgataagt cgatgcacca acaactgacg gtgcaaataa
    23761 aagactcccc aagaataccg aaccaacaat accctttatt ttccgaatgg aaaatttatc
    23821 tttttttaat aatgacaatt ctaatcctcc accttcactt tttatttcct aatagtaaac
    23881 actatttttt attctcaaaa attgaacttc taaaatcacc ggtttggtca agataagctt
    23941 taaagattgc ttttttcagt ttaagaactc tactatttgt ctcaggatat aatttggcaa
    24001 cttcatcctc agcatcaaat tttactgcat cttcaatcat tttttcaagt ctattaatat
    24061 tatcaatagt cactttctgt tgtcgagccc aagaaccgtt tggatcgata aaactaactt
    24121 tatttaactt tccaaattta tcttctcttt ctttatacat atctttcttg aaatctatcc
    24181 aagaattata ctggttatta aatacttttg aaagaacaat ttcatcagta actaaaccta
    24241 tttgtttacc atatgatgta ataacttttc cttgagcttt cgcttctttt tcatactgat
    24301 tagaaatata tggaaccata ccgtctttgt accccttggc tgccaataac tcaaatgcaa
    24361 tacgtcgtcc cattaaatct cctggtgttc ctattttact gctcaatgct gaataaattg
    24421 gtgagaatag attaattgta tagtagccat tccgcttata agttgcttca tctacataac
    24481 ctcttcttgt tataatatca tgttctatca aactgttaaa tgtagttaat ttagtaagtt
    24541 cttctggttt taatctacgt acaacattcg ttgcataaac agaatttcca tcaggatcag
    24601 gtttatattc attttctatt tttcttaata aatcatattt ttgatttgta tctaatttag
    24661 ctacagcttt accttctagt atttcaagca tgtatattac atcaaacata ttatgcatat
    24721 acttatttag atcatcaaca cttccaaatc gttgagttgg atctgctact tgaagccttg
    24781 ttgattcttc tgattgatca tattttaata tggaattaat agtgactgtt ggatcattag
    24841 gatgatcagg agcttgtagc agtcctttag cataaaactc tggtccaagt ccatttcgtc
    24901 ttccatagcc tccaagataa atttctctat ctgagttatg tgtcatttcg tgtgtataag
    24961 ttaccgcacc atctttatca agcatgcgat atgccatata atagaatgca tcccctgtag
    25021 catatgctcc attagaatta tgaacaacat tatttcccgc tggaccgaag aaatgtttta
    25081 tagctggatg attagtttca aaagttgctt gatatgtatc tttatcttct ttttcatctg
    25141 taccaaatct aaatgcatca tagactagaa cacttctata taatttttct ttatttttat
    25201 catctagtat tctataccaa taatcatagt gatctctaaa tctaacagcc gcttctttag
    25261 cttttttctc aacatagtca tttaaatcag ttcctgctgg atgttcttta cttctatatc
    25321 tatcataagc accgaaacct atagtcgaaa tgttggctat aataaacacc gatttttcag
    25381 gtaatgttaa tagcggcaac accatacttg gatatttcca agatgggcta gttaatctat
    25441 catatactcc aattgaatat ggactaccag ctattgattg cttatcactt acctctttaa
    25501 tagtagattt ttcttctaca atatatgctt tagtttgttc tttaaaccac tcattatttg
    25561 ttttatctgg tacaaatgct tttctatatt tctctaatgc atcaaataaa ttattagtct
    25621 tataattttt cgctaataaa acattataag ttataacatt attttttgct agtaagttat
    25681 tatatcccga tttacctagt tcgataacat tatctaacgc tgaactattt gatttaccga
    25741 agaaatccaa gtggtacatg actaaatctt tcgcttttgt atcacgatat ttgaagtcgt
    25801 accaacgctc taagtatgtt aatcctagaa gtaaagcttc tttattattt ttaattttct
    25861 cgattacata attatctatt accttattgt tattttcagc tattgcagca tctgcagtaa
    25921 gaagttttgt caaactatct ttcaaattag tttttgtggt attgaattgt tcttctaaat
    25981 ataactccgt taaactaaca tccttagaaa catctaatac ttttctaatt gcctctgatt
    26041 tatattctac actatttaat gctggtaata cttcatctaa aatattttga taattgcgaa
    26101 gtaatgtatt cggtgtataa attaagtttg taccgcctat tctatactct gctacatttg
    26161 aaaaatcagt ttgataattt acattaagtg tctctgatgt attatccgcg taatatagta
    26221 atagtttatt tatacttgat ttatttttgt taatatcact aattacttct ttatctttca
    26281 tagggactac tgacaataat tctttattat aaagattact acttgtctct actaaatttc
    26341 cgtacttaac aattgtttct ctattataaa acggtaatag tttttcaata tttttatata
    26401 ctttttcttt tgatgaatca gcattctcaa gatttttata gtcagttaca tatctagaag
    26461 agaaattaaa atcttctgtt ttaatagtat ttttagatac aaaagtagct tttttctctt
    26521 ttatttgtgc atcttctaat acttctcctc tttgaacagt agaatcctta gttaagattt
    26581 catcatcttc ttgtactacg ttcacaacct tattattttt attactgtat gtgccatttg
    26641 cttttatact attaaaatta taacctgcaa tagcattacc attcgttaca ttaacatcgc
    26701 ttagtacatt agaaagtcga ccggattttt ctaatcctcc aaccggatcc caaagattac
    26761 caactactcc accaacgttt gcaaaacgtt gaacattatt tagatttcct tcagcataac
    26821 tattactaat aagcgcacta ttttctactg caccaactat tccaccaata gactggtctc
    26881 cttgtgttgc atttgaagat aaatcgattg atgcgaacga cttatctatt aatcccctcg
    26941 gaccagaaag tttgcctact aaacctccga tttgataact agcaactgtt ttatatgtat
    27001 tagttattct acctgtatag ctactgttag aaatagtaga attattaact tgtgatacta
    27061 atcctcctat gctacgttcc ccagctatcg ctccatcagc atgaacgtta tcaatatgag
    27121 tattgttatt tgcttctttc gcaagtgttg cagtatcgtc ctttgcggaa atattaacat
    27181 cttttagtga aagtttttct actgtagcac catttaattc cccaaataat ggttttttca
    27241 aattataaat agcataatat ttctcattat ttgttcctac taatattcca tggaatacat
    27301 tattcacata actttcttga ccatctggaa gttcaacttc acgagcatcc atagttgctc
    27361 ctaaacggaa tgtgccatta ggattgctat tcattgcatc tactaaattt ttaaatgatg
    27421 tatatacccc agtttcactt tgctgagttt ttggtaaata gtatgtataa ttttctagta
    27481 cattattatt ttcatgttgt atcagactat ttgcacttgc tactatctta taaacatctc
    27541 tattatcttt agtatcatta gtaatgcttg taactggtag catcacatct ttaaagttct
    27601 ctgatttaac tttcataaag taattttctg cattacttgg taaagaagca agtgaagtta
    27661 catgtcgata cttattacca tcttttgaat atagttctac agaagatata tttctaagtt
    27721 ctaatttctt aataacttct ttttcatctt tagcgtcatc ttttttctca tctttatgac
    27781 gataaagttc atcgtatact ggtggaattt cattacctgc tataatactc ttaatccaag
    27841 ctaattgtgt aggagataaa atcaatccgc ctgagcgatt ttgtgctcca ttttgatgca
    27901 caccaataac ttcaccatta gcattaaata ttcctccacc actcatacca ggatttccac
    27961 cttgatattg aacaccgtag gtgttattcg catattcttg ttccatttct accgtagcat
    28021 cttttaagtg cgtatatttc ctagctggat atccatgaac atttagtttg tcattaagat
    28081 ttactttcga ataattttta actaattcta catgttctct gccagttgtt tcaggtagct
    28141 taatcactgc taaatcatag ataaatcctt ttggataatc ttttttatta taaaaatgaa
    28201 tattgttagc agtaaatgtt cctttttgtc catcaggagt cacccactca tatacgtttt
    28261 tagatttatc acctctaaat tcgccagtag tattatcagt agaattatta atgaaattat
    28321 gtgctactgt taaaagtaca tttggtgcaa taaaagtagc tgatcctact ccagtaacct
    28381 tcgacgaatc tgtaataaag ttcatattaa ttaatgcact agattttttc tgaatactca
    28441 tttcttctgg tgtattagta ttttcattat ttggtttagt atcttctgca ctaggttgtt
    28501 cgattttacc agtatattct ttcagtgctt ctactttctc tggctcgact at
//
LOCUS       DBEJJV010000027        27498 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.027, whole genome shotgun sequence.
ACCESSION   DBEJJV010000027 DBEJJV010000000
VERSION     DBEJJV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 27498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.027"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            149..871
                     /locus_tag="ACL3GT_001355"
     CDS             149..871
                     /locus_tag="ACL3GT_001355"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HGR0517018.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1088..2422
                     /gene="pepC"
                     /locus_tag="ACL3GT_001356"
     CDS             1088..2422
                     /gene="pepC"
                     /locus_tag="ACL3GT_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HGR0517019.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(2478..3389)
                     /locus_tag="ACL3GT_001357"
     CDS             complement(2478..3389)
                     /locus_tag="ACL3GT_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HGR0517020.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3413..4216)
                     /locus_tag="ACL3GT_001358"
     CDS             complement(3413..4216)
                     /locus_tag="ACL3GT_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HGR0517021.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4244..5233)
                     /locus_tag="ACL3GT_001359"
     CDS             complement(4244..5233)
                     /locus_tag="ACL3GT_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0517022.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5466..6485)
                     /gene="adhP"
                     /locus_tag="ACL3GT_001360"
     CDS             complement(5466..6485)
                     /gene="adhP"
                     /locus_tag="ACL3GT_001360"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HGR0517023.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWAVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(6837..7649)
                     /locus_tag="ACL3GT_001361"
     CDS             complement(6837..7649)
                     /locus_tag="ACL3GT_001361"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0517024.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            7839..9257
                     /locus_tag="ACL3GT_001362"
     CDS             7839..9257
                     /locus_tag="ACL3GT_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HGR0517025.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLVITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            9310..10017
                     /locus_tag="ACL3GT_001363"
     CDS             9310..10017
                     /locus_tag="ACL3GT_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0517026.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            10112..11086
                     /gene="folP"
                     /locus_tag="ACL3GT_001364"
     CDS             10112..11086
                     /gene="folP"
                     /locus_tag="ACL3GT_001364"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004156 - dihydropteroate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HGR0517027.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALATGADLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            11088..12410
                     /locus_tag="ACL3GT_001365"
     CDS             11088..12410
                     /locus_tag="ACL3GT_001365"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HGR0517028.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALGDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            12391..12945
                     /gene="folE"
                     /locus_tag="ACL3GT_001366"
     CDS             12391..12945
                     /gene="folE"
                     /locus_tag="ACL3GT_001366"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA];
                     GO_process: GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HGR0517029.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            12988..13800
                     /gene="folK"
                     /locus_tag="ACL3GT_001367"
     CDS             12988..13800
                     /gene="folK"
                     /locus_tag="ACL3GT_001367"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA];
                     GO_process: GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HGR0517030.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(13845..14162)
                     /locus_tag="ACL3GT_001368"
     CDS             complement(13845..14162)
                     /locus_tag="ACL3GT_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HGR0517031.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            14519..14965
                     /gene="rplM"
                     /locus_tag="ACL3GT_001369"
     CDS             14519..14965
                     /gene="rplM"
                     /locus_tag="ACL3GT_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HGR0517032.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            14984..15376
                     /gene="rpsI"
                     /locus_tag="ACL3GT_001370"
     CDS             14984..15376
                     /gene="rpsI"
                     /locus_tag="ACL3GT_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HGR0517033.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(15638..16060)
                     /locus_tag="ACL3GT_001371"
     CDS             complement(15638..16060)
                     /locus_tag="ACL3GT_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0517034.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            16207..16383
                     /locus_tag="ACL3GT_001372"
     CDS             16207..16383
                     /locus_tag="ACL3GT_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517035.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            16785..18998
                     /locus_tag="ACL3GT_001373"
     CDS             16785..18998
                     /locus_tag="ACL3GT_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIM-barrel domain-containing protein"
                     /protein_id="HGR0517036.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(19220..19696)
                     /locus_tag="ACL3GT_001374"
     CDS             complement(19220..19696)
                     /locus_tag="ACL3GT_001374"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HGR0517037.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQAQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFSKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            19919..23122
                     /locus_tag="ACL3GT_001375"
     CDS             19919..23122
                     /locus_tag="ACL3GT_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HGR0517038.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKGG
                     AITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTARLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYYWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            23502..23878
                     /gene="tnpA"
                     /locus_tag="ACL3GT_001376"
                     /pseudo
     CDS             23502..23878
                     /gene="tnpA"
                     /locus_tag="ACL3GT_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148688.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            24060..24122
                     /locus_tag="ACL3GT_001377"
                     /pseudo
     CDS             24060..24122
                     /locus_tag="ACL3GT_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596946.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(24266..24895)
                     /locus_tag="ACL3GT_001378"
     CDS             complement(24266..24895)
                     /locus_tag="ACL3GT_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HGR0517039.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(24905..25906)
                     /locus_tag="ACL3GT_001379"
     CDS             complement(24905..25906)
                     /locus_tag="ACL3GT_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0019200 - carbohydrate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HGR0517040.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(25937..26578)
                     /locus_tag="ACL3GT_001380"
     CDS             complement(25937..26578)
                     /locus_tag="ACL3GT_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HGR0517041.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(26597..27412)
                     /locus_tag="ACL3GT_001381"
     CDS             complement(26597..27412)
                     /locus_tag="ACL3GT_001381"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HGR0517042.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         8281 a         5116 c         6059 g         8042 t
ORIGIN      
        1 tttgaggttg cagatagaac tgacgaagtc agtaacatat atacggcaag gcgacgttga
       61 cgcggtttga agagattttt gaagagtatg aaacgaaaag gaggttggtc attgtactag
      121 cctccttttg atatgatata atagttctat gagattagat aaatttttag ttgcctgtgc
      181 ggtgggaagt cggactgagg tcaaaaactt gctcaaggct gggcgcgtga ctgtaaatgg
      241 taaaaaagaa aaatcagcta aattgcagat tgatgaaaaa atagatgaga ttcgctttga
      301 tgggcaagtg ttggagtatg aagagtttgt ctactacatg atgaacaagc ccaaaggagt
      361 tatctcagcg actgaggatc ccaagcacag aaccgttctg gacttgttgg atgacttggc
      421 gcggagtaag gaagtttttc cagtaggacg cttggatatt gacacgcatg gtcttttgct
      481 cttgaccaat aatggtcagc tggctcatgt tcttctttcg cccaagcgtc atgtggacaa
      541 gacttatcag gctcaggtca agggaattat gacccaagaa gatgtggaga catttatcaa
      601 gggcattccg ctcaaagact ttacctgtca gcccgctaga ctggagattc tttccacaga
      661 tgcagaaaag aatcagagcc aaatccgtgt gaccattgca gaagggaagt ttcatcagat
      721 caagcgtatg gtgggctact gtggcaagga agtggtggac ttgcaacgat tgactatggg
      781 aactttagta ttagatgaga acctggaacg aggggaatgg cgtcgcttga ccaaggaaga
      841 attagaaatt ctccgcgcta atattattta atttagttta atactcaatg aaaatcaaag
      901 agcaaactag gaaactagcc gcaggctgta cttgagtacg gcaaggcgac gttgacgtgg
      961 tttgaagaga ttttcgaaga gtataaattc gaaaaaggtg agggagaatg tccttacctt
     1021 ttatgttttt tagttgcttc ctttgtgaaa agagttataa tagactgtag aataaaagga
     1081 ggaatctatg aacgcgattc aagaatcatt tactgataaa ctatttgcca actatgaagc
     1141 aaatgtaaaa taccaagcga ttgaaaatgc tgccagccac aacggaattt ttgcagctct
     1201 ggaacgtcgc caaagccatg tagacaacac acctgttttc tcattggatt taaccaagga
     1261 caaggtcact aaccagaaag cgtctggtcg ttgctggatg tttgcggctc tcaacacctt
     1321 ccgccacaaa ctcatctcgc aatacaaatt ggagaacttt gagttgtcac aagcccacac
     1381 tttcttctgg gataagtatg agaaatcaaa ctggttcttg gagcaagtca ttgcgacttc
     1441 agaccaagaa ttgactagcc gcaaggttag cttcttactc caaacacctc aacaagatgg
     1501 tggtcaatgg gatatggtcg tttccctctt tgaaaaatac ggtgtcgtgc ctaagtcagt
     1561 ttatcctgag tctgtttcat ctagcagcag tcgtgagcta aatgcgatcc ttaataaatt
     1621 gcttcgtcaa gatgctcaaa tcttgcgtga tttgcttgtt tctggtgcag atcaagtgac
     1681 tgttcaagct aagaaagaag acctcttgca agaaatcttt aactttcttg ctatgtcatt
     1741 aggacttcca ccacgcaagt ttgactttgc ttatcgcgat aaagataaca actacaaaag
     1801 tgaaaaagga atcacaccac aagagttcta caagaaatat gtcaatcttc ctttagaaga
     1861 ctacgtttct gttatcaatg ctccaactgc tgataaacct tacggaaaat cttacacagt
     1921 tgagatgttg gggaatgtgg ttggtagccg tgcagttcgt tacatcaacg ttccaatgga
     1981 gcgcttgaaa gaattggcga ttgcccaaat gcaagcaggt gagactgttt ggtttggttc
     2041 tgatgtcggc cagctcagta accgtaaggc tggaatcctt gcgacagatg tttatgactt
     2101 tgaatcaagc atggacatta aacttactca agacaaggct ggacgtttgg actatagcga
     2161 aagcttgatg acccacgcca tggtcttgac aggtgttgac ttggacgaaa atggtaaatc
     2221 aaccaagtgg aaggttgaaa actcatgggg agacaaggtc ggtacagatg gttactttgt
     2281 tgcctcagac gcttggatgg acgaatacac ataccaaatc gttgttcgta aggaattgct
     2341 gacagcagaa gaacaagctg cctatggagc agaaccaatt gtacttgcac catgggatcc
     2401 aatgggagcc ttggctaaat aaaagcatag aaaaaaggaa tcagatttta gaacctggtt
     2461 cctttttagt tgcttgatta catgatgtga agaacatgtg ccacaatacc cactgcgaag
     2521 agggcaagga taatagtgat tggagatact tttttcttaa gtaagtacat gcaaagtaaa
     2581 gtaaggagta gtcctgataa tccaggaatc aacatatcca agttttgttg gaaagtagta
     2641 actttttcag gagtttgaga caatccttgt cctacttgtg cgaatgcttc ttggatacct
     2701 ttagaccctt ctggcaattt atcccaatgg atataagcct tttcatctag ttgaacttta
     2761 gaaacatcga aagcaaattt aatatttacc cagcgttgaa caaggacagc aagaatgaac
     2821 atcccaagga tagaagctcc tttagtgata tcttgaagga taccaccaga catatcttta
     2881 gtgatttctg atccagcctt gtatccaatc tcttgaacat accacaagaa tgacatacga
     2941 atcaagttcc atgcaacaaa gaagaggagt ggccccaaga tattgccagt aagggcaagt
     3001 gaagcaccga gagatccaag gattgggcgt actgtaaacc agaatactgg gtcaccgata
     3061 ccagcaagag gtcccatcat accgatttta accccttgga tagcagcgtc atcgatttcc
     3121 acaccgttag cacgttcttc ttcaagcgca agagtaaccc ccatgactgg agcagctacg
     3181 tatggatgag tgttgaagaa ctcaaggtga cgctcaagag cagcgatttg atcttctttt
     3241 ttagtataga gttttttgat agctggaatg agtgtataag cccagcccaa gttttgcatc
     3301 cgttcaaagt tccaagaccc ttgtaagaag gttgaacgcc accaaacttt tttacgatct
     3361 gatttagtta attgaagttt ttcagtcatg atgttttcag tcctttctta tcttagtagt
     3421 cttctaggat atcgccgatt gggtcgttag aagttgcggc tcctccgcca ccatttccac
     3481 cagttttaga aaggtgaagg tagataagag cgatagcaac accgatagca ccgaatccga
     3541 ttagagtaat atctgacaca gcagcgagaa cgaaaccaag agcgaagaat ggccatactt
     3601 cacgagttgc catcatgttg ataaccatgg cgtaaccaac ggcaacgacc ataccaccac
     3661 cgatagccat accatctttg agccagtctg gcatggcact aaggatactt tgtacagttt
     3721 cagttggtac cataaggaga agagctgcag gaagcgcgat acgaagtcct tggaagagta
     3781 gcgcaatgaa atgcgcacgc tccacagcgc cgaagtcacc ttttttagcg gcagcatctg
     3841 cagtatgaac caaaccaact gaaattgtac gaacaatcat tgtcaagaaa agtccagcta
     3901 cggcaagagg gatagcaacc gcttgggcaa caccgatacc agtcttggta aagtcaccac
     3961 caagaaccat gataatggca gcagcgacag aagcaagtgc agcatcagga gcgatagcag
     4021 caccgatatt tgaccaacca agggcaatca tttgaagcga tccaccgagg ataatccctg
     4081 cttccaagtg acctgttaca agcccaataa gggtacaggc tacaagtggt tggtgaaatt
     4141 ggaactggtc gaggatgcct tcaagacctg caaagaaggc tacaacgact actaaaacca
     4201 tagaaataat agacatgttt aaaatccttt cataaataat ggcttatttg acattggctt
     4261 tgttaatcaa gtcaaacaaa tcttttttag aatcatttgg tactttacgg acatcaaatt
     4321 caacacccaa gtcacgcatt ttttcaaatg tagcaacatc ttctttgtcc atagacaaaa
     4381 cggtattgac caatgtttta cctgttgagt gagccataga accaacgtta agagtcttga
     4441 ttggcacgcc gccttcgatg gcacgaaggg catcttgagg tgtttcaaac aagataaggg
     4501 catgtgtttc tccaaaacgt gggtcttttg aaatctcaat cagtttttga attggaacca
     4561 cgttagcctt gacattacct ggagctgctt gtttaatcaa ttctttacga aggtcgtctt
     4621 tagccacgtt atctgaagca acgatgatac gatttgcttt tgaatctgga gtccaagcag
     4681 ttgcaacctg accgtgaagt agacgtgtgt caagacgggc aagattgatt ttcaatttac
     4741 cgtctccgat aacagttcct tctgggatag cagtttgggc aactggagca gctgcagcgc
     4801 ttgcaacttc ttcaactgga tttagctctt ctggaagagc tttgatgcca tctttggctt
     4861 ctttaatgat attagcagcg actttttcta cacctgcagc agcgtccatg aggcgctctg
     4921 tgtaggcttg aatcaacatc ggtaagttaa gtcctgtgat gatggcaaac ttacgctcag
     4981 gattttctcc catcacgcga ctagcttggt taaatggaga accactccaa aggtcagcca
     5041 aaactagaac ctcatcttct gcgtcaaatg cagcaacagc gttattaaac ttagcgtata
     5101 gatcatcagg accttcattt ggcataaagg tcacaacttg aaccttttct tgttcaccaa
     5161 agatcataga tcctgactga tgaatacccg cagcaaattc gccgtggctc gcaataatga
     5221 ttccgatact cattattgtc attcctcctt ttttgtttta gttttcattt aagaaaactt
     5281 taagactgtt taagtataaa ccgttttcat aaaaaaagca actatttatc ataaaaaatt
     5341 aaaaaatttt tatttttgta tgttgatatg ttgagttttt gaggagtaat cttgaattct
     5401 tatttaaaat ttaatataaa aaagttggaa gaagcttcca acttttaaaa taggtttcta
     5461 ttagattagt gggtgaagtc gagtaccata cgtccttgga tttggccttt ttccatttcg
     5521 tcgaaaatgg caacagcatc ttctactgga cgtttttgaa caactgggac taccagacct
     5581 tctgcaccaa attggaaggc ttcttctaag tctttacgag ttccgacaag agaaccgatg
     5641 acttggattc catcgaggac tgttttaacg atgctgagtt ccatcatttc agaaggaaga
     5701 ccaacagcga cgacgcgacc accagcacga atggagtcaa cagcctggtt gaaggcaact
     5761 ttagacacag cagttacgac agctgaatga gctcctccat cagttttttc tttaatgagt
     5821 ccagctacat cttcaacttc gaggccgtta atcacaatgt cagcgcctac ttcttttgca
     5881 agggcaagtt tgtcattgtt gatatcgact gcgataacat gagcattgaa tactttttta
     5941 gcgtattgaa cagcgaggtt accaagtcca ccagcaccgt aaagaacagc ccattggcct
     6001 ggttcaactt ttgcttcttt gatagcttta taggttgtta ctccagcaca tgtgatagaa
     6061 gaagcttggg ctggatcaag tccgtcagga actttgacag catagtcagc agttacgata
     6121 cattgttcag ccataccacc gtctactgag tagccagcat ttttcactgt acggcaaagg
     6181 gtttcgcgac cagttgtaca gtattcgcaa gtgccacatc cttcaaagaa ccaagcaacg
     6241 ctgacgcggt caccgacttt aaggcttttc acatctggag caatctcttt aacgataccg
     6301 ataccttcgt gcccaagaac acgtcctggg acttgaccaa agtcaccatg agcaacgtgg
     6361 aggtcggtgt ggcaaacgcc acagtattca acttctacaa gtgcttcccc agtttcaagt
     6421 ggacggagta ctttttcttc aatagcaaca ccagtgcttt ctggatttac aacaacagct
     6481 ttcatagcta tcctccttga tattgaccga gaacagggac aacgggactg gattgatttt
     6541 ttgtcaacag agtcgagtgt gacgagctct cttgtattta tatgtgaagt atatcacaaa
     6601 agaaagcctt ttccaaggtt ttggagacaa aaagtagaac aatcgattaa ctggttgatg
     6661 agactgtgaa aagagcacaa agaccagctt gcaagctggt catactcttc gaaaatctct
     6721 tcaaaccacg tcagcttcat ctacaacctc aaagcagtgc tttgagcaac ctacggctag
     6781 cttcctagtt tgctctttga ttctcattga gtatcagtat aggttataag aataagttat
     6841 aagaataagt cttgtagggt tttggcaacc ccatcttggt cgttggtaag ggaaatttgc
     6901 tcatctgcat aagggagtag ctctggattg gcatttttca tggcataacc cttcccagca
     6961 aaagcgagca tttcggtatc attgtgttca tctccaaagg caatcaaatc ttttttgtca
     7021 cgattcatta tcttgagcaa gtagtccaaa gcaaaggcct tgttgacacc ttttggggta
     7081 cattcaagga tattgagcgg acctccccag gtattgatag aaagttgatg ctggtagaag
     7141 gcgttcattt cttttgccaa ggcatatttg tcactggctc tggtctgcaa gaggatacag
     7201 ttagggtcct tggtcaccaa ttcaggctgg aattgatctt caggctggaa agcttctaca
     7261 ccaaatagtt tgggattggc aatttcttca ttgggatttg taatgtagaa ttttttacga
     7321 tattctccag cgataaaatc ggcttgaatg tcctctgaac gttgaaccat atctagcaga
     7381 tattttttgt ctacagtcaa acacttttca aaatcccaaa cttggtctgg taaatgagta
     7441 agggatccgt tgaagttaat cataggagtg tctaagccca gttcacggta aaaatctttt
     7501 gacatacggt aagggcgacc tgtcgtaata ataacctgat ggcctttttc agcaactttt
     7561 ttgatggttt ttttggtaaa gtcagaaatt tgactgtctg agttgagcag ggttccatct
     7621 aggtcaactg caataatttt tttcgtcata tggacctttc tagtgtgttt tcagataaga
     7681 tgtcttctat tataacagaa agcaggcaga aaagcagatt ccaaacaaaa aatgaaattg
     7741 gattaatttc ttaaacaaat caaacaaaga cattgaaaaa gtgaatgata aatgatataa
     7801 ttctattatt gttcgtaaaa attaaaagga gattgatgat ggacaaatta tttaaactaa
     7861 aagagaacgg tacagacgtt cgtacagagg ttctcgctgg tttaacaact ttctttgcaa
     7921 tgagctatat tctctttgta aacccacaaa ttctttcgca aacaggaatg cctgctcagg
     7981 gtgtgtttct tgcaacgatt atcggtgcag ttgctggtac cttgatgatg gccttctatg
     8041 ctaacttgcc atacgctcaa gcaccaggta tgggactcaa tgccttcttt acctttacag
     8101 tcgtatttgg acttggttat tcatggcaag aagccctagc tatggtcttc atctgtggga
     8161 ttatttcatt ggttattacc ttgacaaatg ttcgtaaaat gatcattgaa tcgattccaa
     8221 atgcccttcg ctcggctatt tcagctggta tcggtgtctt ccttgcctat gtagggatta
     8281 agaatgctgg acttttgaaa tttacgattg atccaggcaa ctatactgtt gtaggagaag
     8341 gggctgacaa agctcaagca acgattgcag caaactcttc agcagttcca ggcttggtca
     8401 gctttaataa tccagctgtt ttagtggctc ttgcaggact tgccattact atcttctttg
     8461 tcatcaaagg gattaaaggg ggaattattc tctctatctt gacaacaact gttcttgcta
     8521 ttgcagttgg tttggttgat ttgtctagta tcgattttgc taataaccat gttggtgcag
     8581 cttttgaaga tttgaagaca atctttggtg cagctcttgg ttcagaaggt ttgggagctt
     8641 tggtttcaga tacagctcgc ttgcctgaaa ctctgatggc cattcttgcc ttctcattga
     8701 cagatatttt tgacacaatt ggtaccttga tcggtacagg tgaaaaagtt ggtattgtag
     8761 cgacaaatgg tgaaaatcac caatcagcca aattggataa ggctctttac tctgatttga
     8821 ttggaacgac agtcggtgcc attgcaggta cttcaaacgt aacgacttat gttgagtctg
     8881 ctgctggtat cggtgcaggt ggacgtactg gtttgacagc cttggttgta gctatctgtt
     8941 ttgcgatttc aagcttcttt agcccacttc tagcgatcgt accaacagcg gctacagctc
     9001 caatcttgat tatcgttggg attatgatgc ttggtagctt gaaaaatatc cattgggatg
     9061 atatgtctga agcagttcct gccttcttca catctatctt tatgggattc agctactcta
     9121 tcactcaagg gattgcagtt ggtttcttga cttacacttt gactaagctt gtcaaaggtc
     9181 aagttaaaga tgttcatgcc atgatttgga ttttggatgc cttgtttatc cttaactaca
     9241 tcagcatggc cttataatag aatgacccag ggggatttcc cccctttttt aatacaaagg
     9301 agataggtga tgaaagagaa aaatatgtgg aaagaattgt tgaatcgtgc aggctggatt
     9361 ttggtctttt tacttgccgt ccttttatat caggttcccc tagtggttac ctctattttg
     9421 actttaaaag aagtagccct gctacagtca gggctgatag ttactggcct ttcaattgtg
     9481 gttctggctc tatttattat gggagctcgt aaaaccaagt tagctagttt taatttttct
     9541 ttttttagag ctaaagattt ggcacgtttg ggcttgagtt atttagttat tgtcgggtca
     9601 aatatacttg gttctatctt gttgcaactg tcaaatgaga cgacaacagc taaccagtct
     9661 cagattaacg atatggttca gaatagttct ctgatttcta gcttcttctt gctagccttg
     9721 cttgctccaa tttgtgagga aatcttgtgc cgtgggattg ttcctaaaaa gattttccga
     9781 ggcaaggaga acttgggatt tgtagtcggt acgattgtgt ttgctttatt gcatcaacca
     9841 agtaatttac cttctttatt gatttatgga ggtatgtcga cagttctatc ttggacggcc
     9901 tacaagaccc aacgtttgga aatgtcgatc ttgcttcaca tgattgttaa tgggattgct
     9961 ttctgtttgt tggctcttgt ggtgattatg agtcggacat taggaatttc tgtttaaaag
    10021 tttttatgta ggaaccgacc tctttctact agggaaagat gaatgcaatc gtgtccatct
    10081 ttttcttttt atggtaaaat agaaaaataa tatgatgaaa atccttgagg gagtgaccga
    10141 tatgtcaagt aaagccaatc atgcaaagac agttatttgc ggaattatca atgtaacccc
    10201 agactccttt tcggacggtg gtcaattttt tgctcttgag caggcactcc agcaggctcg
    10261 taaattgata gcagaaggag ccagtatgct cgatatcggc ggagaatcga ctcggccggg
    10321 aagtagctat gttgagatag aagaggaaat ccagcgtgtt gttccagtga tcaaagcgat
    10381 tcgcaaggaa agtgatgtcc tcatctctat tgatacttgg aagagtcaag tagcagaggc
    10441 tgctttggct actggtgccg atctagtcaa tgatatcact ggtctcatgg gtgatgaaaa
    10501 aatggcccat gtggttgcta aagctggagc gaaagtggtc atcatgttta acccagttat
    10561 ggctcgacct cagcatccta gttcgcttat cttccctcat tttggctttg gtcaaacctt
    10621 tacagaaaaa gagttagctg actttgaaac attgccaatc gaagacttga tggtggcttt
    10681 ctttgaacga gcactagcga gagcggcaga agctggtatt gcaccagaaa atatcctgtt
    10741 ggatccagga attggctttg gtctgaccaa gaaagaaaat cttctccttt tacgggacct
    10801 ggataaacta catcagaagg gctatccaat ctttctcgga gtgtcgcgca agcgatttgt
    10861 catcaatatc cttgaagaaa gtgggtttga agtcaatcct gagacagagc ttggtttccg
    10921 aaatcgggac acggcttcgg ctcatgtaac tagtatcgct gcgagacagg gtgtagaagt
    10981 ggtgcgcgtg catgacgtag ctagtcacag gatggcagtt gaaattgcct ctgccattcg
    11041 tctggctgat gaagcggaaa atttagattt aaaacaatat aaataagatg aaagaaattg
    11101 aaaacaatca gtggattgct aactaccgga cggatcaacc gcattttggc ttggaacgaa
    11161 tggtggaact gttagctttg cgtggcaatc cccatcttaa actcaaggtt ctccatatcg
    11221 gagggactaa cggcaagggc tcgactattg cttttttgaa aaagatgcta gaaaagctag
    11281 ggctgagagt tggcgtgttt agttcgccct atctcattca ttacacagac cagattagca
    11341 tcaatgggga atcgatctca gaagcgaggc tagaagctct catggcagac tatcagtctt
    11401 tgctggaggg agaagcggtc gccaatttac agggcacaac cgagtttgag attatcacag
    11461 ccctagccta tgactacttt gcctcagagc aagtagatgt ggctatcatg gaagttggca
    11521 tgggtggact tttggatagt accaatgtct gtcagcccat tttgacagga attacaacta
    11581 ttggcttgga tcatgtggcc ctacttggtg acaccttgga ggccatagca gagcagaagg
    11641 caggtattat caaacaaggg atgcccttgg taacagggcg tattgctcca gaagccttga
    11701 ctgtgattga ccgcattgcg gaagggaaag atgcgccgag acttgcctac gggacagatt
    11761 atcaggttcg tcatcaagaa agtgtggtga caggggaagt ctttgactat acaagtgctg
    11821 tcagacaagg tcgcttccag actagcctgc ttggtttgta ccaaatagag aatgctggga
    11881 tggccatagc tttacttgat actttttgtc aagaagatgg tcgagagcta gcaagcaatg
    11941 actttcttgg tcaagccttg gaagaaacaa gttggccagg gcgtttggaa atcgtgtcaa
    12001 gagatccctt gatgattttg gatggagccc ataatcccca tgctatcaag gccttgttgg
    12061 taaccttgca agaacgtttt gcggattatc ataaggaaat cctcttcact tgtatcaaaa
    12121 ccaaagcctt gggggatatg ttggacttgc tgggagccat gccagatacc gagcttactc
    12181 taacacattt tgcggatagt cgggcgacgg atgaaagcgt gctgaaagag gcagctaagt
    12241 ctagaaatct cagctaccaa gattggcatg attttctaga gcagaatttg acagataaaa
    12301 aagaagagaa acaaacagtt aggattgtca caggttcctt gtatttcttg agccaagtga
    12361 gggcctatct gatggagagg aagaacgaga atggatacac aaaagattga agcagctgta
    12421 aaaatgatta tcgaggctgt aggagagaac gctaatcgcg agggcttgca ggaaacacct
    12481 gctcgtgtag cccgtatgta tcaagagatt ttttcaggtc ttggtcaaac agcagaggaa
    12541 catttgtcaa aatcctttga aattattgac gataatatgg tggtagaaaa ggatatcttt
    12601 ttccatacca tgtgtgaaca ccacttcttg ccattttatg gtagagcgca cattgcctac
    12661 attccagatg gtcgtgtggc aggcttgtct aagctagccc gtacggttga agtttattcg
    12721 aaaaaaccac aaattcaaga acgtttgaat atcgaagtgg ccgatgcctt gatggactat
    12781 ctaggtgcta aaggagcctt tgttgtcatt gaggcggaac atatgtgtat gagtatgcgt
    12841 ggtgttagaa aaccaggcac tgcaaccttg acgacagtag ctcgtggtct atttgaaaca
    12901 gataaggacc tccgcgacca agcttatcgt ttaatggggc tataaaaaga atccgtttca
    12961 agcggatttt tctagaaagg aatcattatg gatcaactgc agattaagga tttggaaatg
    13021 tttgcctatc atggtctttt tcctagtgag aaagaattgg ggcagaaatt tgtcgtttca
    13081 gccatcctat cctatgatat gaccaaggca gctacagact tggatttaac agcctctgtc
    13141 cattacggag aattgtgtca gcagtggacg acttggtttc aggaaacgag tgaagatttg
    13201 attgaaacgg tagcctataa actggtggaa cgtacctttg agtcttatcc tcttgtccaa
    13261 gaaatgaagt tggaactgaa aaaaccttgg gcaccggtgc atttgtcact agatacttgc
    13321 tcggtaacca ttcatcgccg caagcaacga gcctttatcg ccctaggaag caatatggga
    13381 gataaacaag caaacttgaa gcaagccatt gacaaactgc gagctcgtgg catctatatt
    13441 ctcaaagagt ccagtgtctt agcgacggag ccttggggtg gagtggagca ggatagcttt
    13501 gccaatcaag tggttgaggt ggaaacctgg ctaccagcac aagacttgtt agaaaccttg
    13561 ttagccattg agtcagagct gggacgggtg agagaagtgc attggggacc tcgtttgatt
    13621 gatttggact tgctctttgt ggaggaccag atcctttata cagacgacct catattgcct
    13681 catccttaca tagcggaacg cctttttgtc cttgagtcct tacaggaaat tgcgcctcat
    13741 tttatccatc cgatattaaa acaaccgatc cgtaacttgt atgatgcttt gaaaaaatag
    13801 aaaaactcta gttttcagtt acttgcaact gaaggctaga gtttttaaaa taggtcattt
    13861 tcttctggga ggaggatagt ttctctaccg tccatgtcta aaaccagtac tcttggggga
    13921 taacgagggt cgaaaggatg gttaaagtca aaatcaatgg ctgtagggag gtgttgactt
    13981 gaaaagtgga aggtaatctt tccttggtta ttaagcaatt gaaactcgag ttcttcttcc
    14041 aattcaaaga cattttttaa gaaatggtcg ataatatacc aaaaagagtc aatgatgtca
    14101 tcaggcaagc tggtaacaat gccaaaacta gcagaccgca tgtgggtatt ggtaaaagcc
    14161 atatctctgt ctcctttctt ttcccttatc atacagcaaa taggattaaa aatcaagaaa
    14221 aggtgatttt ttgaaaagga ttttaactac agggaaaaag aaggaaaaaa attcccaaaa
    14281 atctaccgaa gttaataggt aaattcccaa attaacttga ttatataact ttcagttatt
    14341 ttgagaagtt accgaaaaat attttttata tctattgact tttaggggtg aaatttggta
    14401 tgatagtagg cggtattgtt taccccattt gaaaggcccc ggaaccttcc aaatactttt
    14461 cgatgggaag gaacacccat caccgtaaac aaaaatcgaa ctatatatag gagaaatcat
    14521 gaacaaaaca acatttatgg ctaaaccagg ccaagttgaa cgtaaatggt acgtagttga
    14581 cgcaactgat gtaccacttg gacgtctttc tgcagtagtt gctagcgtac ttcgcggaaa
    14641 aaacaaacca acatttacac cacacactga tacaggtgac ttcgtgattg ttatcaatgc
    14701 tgaaaaagtt aaattgactg gtaaaaaagc aactgataaa atctactaca ctcactcaaa
    14761 ccacccaggt ggattgaaac aaatctctgc aggtgaactt cgttctaaaa atgcagtacg
    14821 tttgattgag aaatcagtta aaggtatgct tccacacaat acacttggac gcgctcaagg
    14881 tatgaagttg aaagtatttg ttggagctga gcacactcac gctgcacaac aaccagaagt
    14941 tcttgacatt tcaggactta tctaaggaaa ggaacaataa agtatgtcac aagcacaata
    15001 tgcaggtact ggacgtcgta aaaacgctgt tgcacgcgtt cgccttgttc caggaactgg
    15061 taaaatcact gttaacaaaa aagatgttga agagtacatc ccacacgctg accttcgtct
    15121 tgtcatcaac caaccattcg cagttacttc aactgtaggt tcatacgacg ttttcgttaa
    15181 cgttgtaggt ggtggatacg ctggtcaatc aggagctatc cgtcacggta tcgctcgtgc
    15241 ccttcttcaa gtagacccag acttccgcga ttcattgaaa cgcgcaggac ttcttacacg
    15301 tgactcacgt aaagttgaac gtaagaaacc aggtcttaag aaagctcgta aagcatcaca
    15361 atttagtaaa cgttaattcg aaagaattac tatacttata cagagcacct ttcggggtgt
    15421 tcttttttta tactttctta ctaaattggt gcaattgaca cagttgttgc gactttagtc
    15481 gcttacaaat gtggctgcaa cctgacaagg tcagttgcct caaaacgtta atcaatacaa
    15541 ttatatcaac gtttcaaagc actcaagagt ttacctcatg ggtgcttttt ttatgttttt
    15601 tgaaaaagtt cacctcaaag tttaccttat tttcacctta ttgttttaga gactgtaagg
    15661 caaattcacc gacggccata gggactacat tagaagtatt gacataaatc tgtgttgtac
    15721 ctgtgtcgct atgtattaga gcttcagaaa tggcttctaa gctcattcct gcttgtttag
    15781 cgagcgttgc tccggtatga cgtagtttgt gtggcgtagc gtgtgtaagc tctgggtgtc
    15841 gttttctgat agttttcatc ttattattga gatagtcaga atgtaaaggt ttattgatat
    15901 tgcctttggt atctatgtaa gtaaagatga attgttctgg attactgatg ataccaaact
    15961 ttgccagttc atatttttgt tgttttttcc atgaagtcag aagttgaagt aagtcattag
    16021 aaatagagaa aatgggaaat gtttccacaa taaaacgcat attatcagat ggttaatgcg
    16081 ttttatattt gggtttgagg cttataaaat aggataagcg tactgaaaac ttagatatga
    16141 caaacaaaat aaaattttta aaagctacat agaaacatgg tataatgtat ctaaaggagg
    16201 tagcatatgt ccttagatat agataaagaa aagatgacaa tcatgggaat agcttttgaa
    16261 aaccgatccg tttttaagag tgtttggtat gctttaagta caaatatgat tgaaggatgg
    16321 cgacctacgg ttagtgatgt tgaaaaatta cgagatgaag ctcttgctct ggggatgact
    16381 taatgaagcg caactgttat gaatcttatg actatgttga tccggataat ttatataccg
    16441 atccgggttc ttcagttcta agaaataagc aggaaggaaa aaagcacgcg agcttgaata
    16501 tcgtatgatt gctagtaaga gtttgaaatt atttatcaat cctatcttag ttaatagttt
    16561 aaaagtagtt tgtttcacaa ctgcataagc ttagaaaagt tgaaaagtga taactcttta
    16621 ataaactctt ggtttgttaa aagatatttt gtccactaca tttttttcaa ttgactatta
    16681 tttgtcatag atataacaga tagaacattg cattcagaat aatgaaaaac gcatcaaaaa
    16741 tggtgcgttc tgtttttatg ctaccataaa aggaggaaaa caaattgaaa atttttaagg
    16801 gagagtttta tcgaatctct gtattaacag acaagctagt aaggttagaa tactctcgaa
    16861 ctggaaattt tgaggataga acgacacaac ttatctataa tagagatttt ggccaagttt
    16921 cgttagatta tatcgagaca tcaaatgtac tagatattat gacggactat tttcatctgc
    16981 actttaataa aggagaattt aacgccgaaa atttatttat agaattaaaa ggaaattttg
    17041 ccgtatatgg tagtcgctgg tattttggtg aatctattga aacgttaaaa ggaacagctc
    17101 ggactctgga taaggcagat ggagcaatct cgttagaaga tggaattatt agccgaaatg
    17161 gtatagcctt attggatgat tctcaaggat ttatttggga tgaacaatct ggttatattg
    17221 agagagaaaa tcaaattgac ctgtatttct ttgcctatgg gcatgattat agaggagcaa
    17281 tcagagactt ttaccatttg actggttcaa cacccttgtt gccaagatat gctttaggca
    17341 attggtggag tagatattgg ccttatacgt cggatgaata cttggattta atagacagat
    17401 ttgaaacaga gaaaattcca ttatctatcg gtgtgttaga tatggattgg catataactg
    17461 acattccagc tcgttttgga agtggctgga caggatatag ttggaataga aacttaatac
    17521 caaatccaga acagttattg caacaacttc atgatagaaa gttaaaactc tccttaaatg
    17581 tccatcctgc tgatgggata cgggcttatg aagaagctta tcctcaaatc gcaaaacgat
    17641 tggggttaaa tgtagaacta gaagaacctg ctatttttga tttttttaat ccctctttta
    17701 gggaagccta ctttaaagat gttcattatg agttagaaaa gcagggagta gatttttggt
    17761 ggattgactg gcaacaaggg acacaaggta tgctagatcc actttggctt ttaaaccatt
    17821 atcactatca ggatagttgt aaaaatgcag aaggtggttt gattttatca agatatgcag
    17881 gtcctggtag tcaccgctac cctgttggtt tttcagggga tactattatt agttggaatt
    17941 ccttaagatt tcaaccctat tttacagcga cagcatctaa tatcggttat agttggtgga
    18001 gtcatgatat cggtggacat atgttggggg attatgacga agagctacaa actagatggc
    18061 tacagtttgg tgtttttagt ccgattactc gattacatag ttctagaagt ccttttaata
    18121 gtaaagaacc ttggtttttt tcagaaacaa catctaagat tatgaagaaa tacctccgtt
    18181 tgagacatca gatgattccc tatctatata ccatgaatgt aaagacacat gaggaaggtg
    18241 ccccattaat cagtccaatc tattatttct atccagagaa tgatgagagc tataatgttc
    18301 caaatcaata cttttttgga acagaactga tggtggctcc cattgtagaa aagatggatt
    18361 tgacattcca atctgcaaaa gtagatgtat ggttccctga aggtgaatgg tatgactttt
    18421 tttcagagaa aaaatacaca ggtggtgtga agttaagtgt ttatagagac atctcgacta
    18481 cgcctgtgtt tgcaaaaagt ggtgcaatca ttcccttggt tggttctgag ataggtatgg
    18541 gtgttgattt acctgaagtt gtagattggt atgtattccc aggaaaacaa cattcttttg
    18601 aaatgcttga agatcaaaat ggtcaaagat ataaaacaag attatcaatc gattgggaaa
    18661 tgggaatggt agagttagca ttacaaggag attctagtat cgttccaagc aatagaaaac
    18721 atagaattca ttttaaagga acgaatgtgt ctataattga attgccaaat aagaatgata
    18781 cagctaaatt tgaatggaaa gataataaaa ggacatcttt aaatgacgaa gtttttagac
    18841 tactaaagac agcttctctt ccatatgaat taaaagatag attgttaaat caattcatca
    18901 atgcgaaaaa ctctcatgac ttaatgaata tcttgcatca tcaggataag gaattgagag
    18961 ggcgtttgtt ggaaatgata tttactagcc aaaactaatt gaaataatta gaaagtcatt
    19021 tgtttagtgt atatgaagat tctgtatggt attcgttatc actggtcaca ttgaaaatgt
    19081 gaaataagca cctacaacat agactttaca acacttcatg ttttatatca tggggtgttt
    19141 ttctatttaa gtcaaagccc atcaaaaaat ctcactattc atcaggttaa aggaaaccta
    19201 atcatagtga gattgtgaat tatagtagag tttgtatcgc ctcttcaatt tgttttgggt
    19261 ctgtttttga agaaaagcgt tcaaagactt gcccatctcg accgatgaga aacttagaga
    19321 aattccattc gattcgtttt cctagtgggc cggatttctg gtcttttaac cagacataga
    19381 gagggtctgc ttccttaccg ttgaccttaa tcttggcaaa acgtgggaag gtggtttgaa
    19441 aatgtaggct acagaaggcg ttgatttcct ctgcgctgcc gggtgcttgt cccataaact
    19501 gattgcaagg gaaatccaat atttcgaagc cctgagcttg atagcgttca tagagttctt
    19561 gaagtccctg gtactggggc gttaaaccac atccagtagc agtgttgaca atcaagagaa
    19621 ctttgccacg atagctatcc aagggagttg cttggttgtt ttggttcaaa acggaaaaat
    19681 cataaagtga agtcatgagg gcctcttttc tttttctaca ttgtaacagt ttttactttt
    19741 ttcgtcgagt cggatggaag atattgttga agaataagtc ttcaatatga tagaaaccgt
    19801 ttacaaataa ctttaaaaat ggtatgattt aattaaaccg gtttacttag ttgctataaa
    19861 tctctaattt gagatttagt tcctattgat tttacaatat gtttattgga gtgtatacat
    19921 gcaaacaaaa acaaagaagc tcattgtgag tttgtcttca cttgttttat caggattttt
    19981 attaaaccat tatatgacag ttggagcgga agaaacgact acgaatacca ttcagcaaag
    20041 ccagaaggaa gttcagtatc agcaaaggga tacaaaaaat ttagttgaaa atggtgattt
    20101 tggtcagacg gaggacggaa gcagtccgtg gacaggaagc aaagctcagg ggtggtcagc
    20161 ttgggtagac cagaagaata gttctgcaga tgcctcaact cgagtcattg aggctaaggg
    20221 tggggctatc actatctcaa gccatgagaa attaagggca gcggttcacc gtatggttcc
    20281 tattgaagct aagaaaaagt ataaactgcg tttcaagatt aaaacagatc ataaagtcgg
    20341 gattgccaag gttcgtatca ttgaggaaag tggtaaggac aagcgattgt ggaattctgc
    20401 aacgacgtca ggaacaaagg actggcagac cattgaagca gactatagcc cgactttaga
    20461 tgttgataaa atcaagctgg agttattcta tgaaacagga actgggactg tttcctttaa
    20521 ggatattgag ctggtagagg tagcagacca gctttctgag gattctcaaa cagataaaca
    20581 gcttgaggaa aagattgatt taccaattgg aaaaaaacat gttttttctc ttgcggacta
    20641 tacttataag gtagaaaatc ctgacgttgc ttcagtcaaa aatggaattt tagaacctct
    20701 taaggaaggg acaaccaatg tcattgtcag taaagatggc aaggaagtga aaaagattcc
    20761 tttgaagatt ctagcctctg ttaaggatgc atacacagcc cgtttggatg actggaatgg
    20821 catcatcgct gggaatcaat actatgattc taaaaatgaa cagatggcca aattaaacca
    20881 ggaattggaa ggaaaggtag ctgatagcct atctagtatt tcaagtcagg cggaccgcac
    20941 ctatttgtgg gaaaaatttt caaattataa aatgtctgca aatctgactg ccacttatcg
    21001 gaaattggag gagatggcca agcaagtgac caatccttct tctcgttatt atcaagatga
    21061 aactgtcgtt cgaacagtca gggattccat ggaatggatg cataaacatg tctacaatag
    21121 tgaaaagagc attgttggga actggtggga ttatgaaatc ggtacacctc gtgccatcaa
    21181 caataccttg tctctgatga aagaatactt ctctgatgag gaaattaaaa aatatacaga
    21241 tgtgattgaa aaatttgtac cagatcccga acatttccga aagacgactg ataacccatt
    21301 taaggctcta ggtggaaact tagttgatat gggaagagta aaagtaatag ctggtttact
    21361 gcgtaaggat gatcaagaaa tttcttctac cattcgctcg attgagcaag tgttcaagtt
    21421 ggtagaccaa ggtgaaggtt tttatcaaga tggatcctat atagaccata ccaatgttgc
    21481 ctatacgggt gcttatggga atgttttgat tgatggcctg tctcaactgt tgccagtcat
    21541 tcaaaagacc aagaatccaa tcgataaaga taaaatgcaa accatgtact actggattga
    21601 taaatcgttt gctcctttgc tggtgaatgg agagctgatg gatatgagtc gtggacgctc
    21661 gatcagtcgt gcaaatagcg aggggcacgt ggccgcagta gaagtactaa gagggattca
    21721 ccgaatagcg gatatgtctg aaggagaaac caaacaacgt ttgcagagtc ttgtgaagac
    21781 cattgttcaa tcggatagtt attatgatgt ctttaagaat ttgaagactt ataaggatat
    21841 cagtttgatg caatccttgt taagtgatgc aggagtcgca agtgttccaa gaacaagtta
    21901 cctatctgcc tttaacaaga tggataaaac agccatgtac aatgcagaga aagggtttgg
    21961 atttggcttg tcactctttt ccagtcgtac cttgaattac gaacacatga acaaggaaaa
    22021 taaacgtggt tggtatacga gtgatgggat gttctatctt tacaatggcg atttgagtca
    22081 ctatagcgat ggctactggc caacagttaa tccatataag atgcctggta caacagagac
    22141 ggatgctaag agagcggata gcgatacagg taaagtttta ccgtctgctt tcgttggaac
    22201 gagcaaacta gatgatgcca atgcgacagc aaccatggat ttcaccaact ggaatcaaac
    22261 attgactgct cataagagct ggtttatgct aaaggataag atcgcctttt taggaagcaa
    22321 tatccaaaac acttcaacag atactgctgc aactacaatt gaccagagaa aactggaatc
    22381 aagtaatcca tataaagtct atgtcaatga taaagaagcc tcccttacag aacaagaaaa
    22441 ggattatcct gaaacccaaa gtgtcttttt agaatcatcc gattcgaaaa agaatattgg
    22501 ttactttttc tttaagaaga gttcaatcag tatgagtaag gctttgcaaa agggagcctg
    22561 gaaggatatc aatgaaggac agtcagacaa ggaagttgaa aatgaatttc ttacgattag
    22621 tcaggctcat aagcaaaatg gagattctta tggctatatg ctcatcccta acgtgggtcg
    22681 tgccaccttc aatcaaatga taaaagagtt agaaagtagc ctcatcgaaa ataacgaaac
    22741 ccttcagtct gtttatgatg ccaaacaagg agtttggggc attgtgaaat atgatgattc
    22801 tgtctctact atttccaacc aattccaagt tttgaaacgt ggagtctata ccattcgaaa
    22861 agaaggggat gaatataaga ttgcctacta taatcctgaa acccaggaat cagctccaga
    22921 tcaggaagtc tttaaaaagc tagagcaagc agctcagcca caagtacaga attcaaaaga
    22981 aaaggaaaaa tctgaagagg aaaagaacca ttcggatcaa aagaatctcc ctcagacagg
    23041 agaaggtcag tcaatcttgg caagtctagg gttcttgcta cttggggcgt tttatttatt
    23101 ccgtagagga aagaacaact aatttgttca tcatctagat gaattacatg aaactgtgga
    23161 aaatagaaaa aatccgaaga aggccaaata tcttcggatt tttcttttaa aaaaggataa
    23221 gttgatactt atccttttta cttcattatg tgactatagc gttttgaaac tagaatagga
    23281 catcataact gctaaaagat ttctataaat tcatttgatt ttcctaatca atttgttcgt
    23341 atcctatttc actctactat attagtccgt ctcgcacctc acggagcgag acaaaacaac
    23401 cacccgctat gcgggtgcgc gtcgaaggtt ataccaaaaa aactccaaac gcgatacaat
    23461 aaaggtgttc aacccacttg taaagcgaaa ggagaaaaaa tatggcacaa aaggctcata
    23521 gtttatctca cacaaagtgg aggtgttcta tcacattgtg ttcaccccta agtatagacg
    23581 aaaagtcatc tataatcaat atagaagtag tttaggcgaa atatttcatc gcttgtgtag
    23641 ttataaaggt gttgaaatga tcgagggtca cttaatgcca gaccatgtac acatgttagt
    23701 cagtattcca ctaaggctaa gtgtttcgag tttcatgggt tatttaaaag gcaaaagtgc
    23761 actcatgatg tttgacaaac acgccaatct caagtacaag tttgggaatc ggcatttctg
    23821 ggcggaaggt tattatgtaa gtccagtagg gcttaatgaa gacacaatta agaaatatag
    23881 tcaagattaa agaaattatc gagtggatga tttcttcacg agtatgaaaa tttgagaact
    23941 agtaaagtat gatatatagt aaaatgaaat aagaacagga caaaatcgat caggacagtc
    24001 aaatcgattt ttaacaatgt tttagaagta gaggtgtact attccagttt caatctacta
    24061 tagcactaga taaattgagt gtaaaagaat atgaggatcc ctttagggat agtggtaagt
    24121 aataccaaag tctcttaaag aggcaagtga cgagtcaaga gcaataaggc ttgaacaacg
    24181 tgaaagccag cgtctttagg cgctggctga tgatttgggc ttatagctct gagataaacc
    24241 acccgttaga cgggtagtta tgattttatc tgagtgtaac atactgttgg gcaatctcgc
    24301 tgatgcggtc aaagttgcct tgggaagcga gtttattgag ttcgccacca attccaacgg
    24361 catctgcacc agcagcgaac cattgaggga tgttgtttag accgactcct ccggttacca
    24421 ttacggaaac ttgtggaatc ggtgccttga ctgcagagat atatgctgga ctgagagtac
    24481 tacctgggaa gagtttgatg atttcactac cggcttcaag tgcagtcgtg atctctgtga
    24541 gggtaataca gcctggaatg tacggtgtgc tgtagagatt gcacattttc gcagtttcag
    24601 catggaaaga tggagaaaca acgtaatttg ctccggctag aatggcatct ctagcagtta
    24661 cggcatcaag cacagtacct gcaccgatac aaacactctg atcgtcctga tacaagtcta
    24721 caagttcctt gatgatttgt cctgcatact gattggtata ggcgatttca atagctttga
    24781 taccgccctt gatacaagca atcgaggctt gtagtccttc ttcctttgta tttcctcgaa
    24841 tgacagcaac aattttctgt ttttttagtt caataattgt atctgatttg gtcatgtaat
    24901 tctcctaacg aatgatatct tgtgcatttg ccagtaaatt ttcaatacta gttgcggaag
    24961 tggagagatg gtctcctgga agagtgcatt tgagagttgc gctcgcaact gcaaagtcaa
    25021 tggtagtttt tagggaggaa tgatggagta gttggtaaag ggcaccagat ataaaggcat
    25081 ccccgctacc aattcgttga tagactgcag tttttagttg gacagactct tcaaatcgtt
    25141 cttccagagc ataggcttga tagacatttt tgtcttgctc atcactagag cggagggtat
    25201 ggaaaatggc cttgaaacca taggcttctt ttaaaagtcg catgcgattt tccacctctt
    25261 ctaggctagc actgtctctt ggaaacatct ctagattttg gtcatcaatc atgagaggat
    25321 caataccgaa gcaatagtca gtaaaacgtg caaacttaga aaattcatac ttggcttcta
    25381 ggactgaaat catctttgtt ctcagattga gatccattga aacgacaatt cctcggcgct
    25441 tggcttcttc caagagtagg agaaggatcg cacggacctc ttgaccgata gctacggtga
    25501 ttccactaaa atgaaaatgg ctaatcccct gaaagagaga atccatatct agcatgtttg
    25561 gccgaatctg gctgatactc gtatgcttac gatcgtagaa aacttcactt tgacgacaac
    25621 caaagccgtt ctccaaatag tagaggccga ttcgatcgcc aagccgacag attgaactgg
    25681 tatcgatttg gtgctgtttc aagaatgtga gaaaacgatc tccaatctcg ttggcaggga
    25741 gtgcggtaaa gactttcgtt gagataccca gggcttgcaa attacaagcg atgttaattt
    25801 ctgatccgcc aaaataagtc gaactggcaa catgatctcc gatactggtg gcatctaatg
    25861 gtgagattcg aattaatggt tcgccaaaca gtaatatttt cgtcatccat tagttccttt
    25921 ctggtttaga atagctttac ttggctaata cttctttcaa ataagcagcg acttcatcat
    25981 cttggcagtt ttcaaagaag tattcttgga agtatttgcc agatatggtg tctttgagga
    26041 agtcttggtc gattgtttta aggatggtca tcaaatcatt gtgggtgatt tgtttcacct
    26101 cgtttaagat acgagcgttg cgttgttcag ggattacacg ttctcttggg tagccaccgc
    26161 ccatttcttc agcaaataag cgttcaaaca tcaatttgag ggtcagttct gccccccagc
    26221 caaatccttt ggcataaggg atagacaagg cgttaccacc attgatttga gaataaaggt
    26281 aagcgtcagt tgggtccact gctagaccac agacaacacc agggaagctg tttaaagcaa
    26341 gcatagcccc tacacccgta ccacagccgg taacaacaaa gtcaactgcc tttgtattta
    26401 aaaggatggc agccattagt ccgttctgca cataagttaa ttgactttct ccttcttctc
    26461 cacgcatacc atagttaaat aattggtagt cttttttatc tgtcgcttct tttagactat
    26521 cgtaaataat gtgattcttg ctagcttgac tattttcatt gattaatgcg attttcataa
    26581 gatcttcttt ctatttttac tcaggttgtt ttccgatgta ggctaagata ccgccatcta
    26641 catataggat gtggccattg acaaaattgc tggcatcact agcgagaaag acagcagggc
    26701 ccatcaaatc ttcaggattt ccccaacgtg cagcaggtgt ttttgcaatg atgaactggt
    26761 caaatgggtg gcgagaacca tcttcttgca actcacgaag aggtgctgtt tgaggagtgg
    26821 caatataacc cggtccaatt ccgttacatt ggatattggc tccaccgtat tcagacgcaa
    26881 tgttgcgggt caacattttc aagccccctt tagcagcagc ataagcgcta actgtttcac
    26941 gtcccagttc gctcatcatc gaacaaatat tgataatctt tccatgccct ttctttatca
    27001 tagaaggaat aactgccttt gaaacgataa atggtgcgtt taagtcaata tcgatgacct
    27061 tacggaaatc agcggcgctc atttcgcaca ttggaactcg gcggataata ccagcgttat
    27121 taacgaggat gtcaatgaca ccaacctctt gttcgatttg cttgaccatg gcttggatac
    27181 cgtcctcgtc tgtcacgtca cagacatatc catgggcttc gatgccaact tcacgataag
    27241 cttcaatccc tttattgacc agatcttgat tgatatcgtt aaagacaata gtagcgccgg
    27301 cttcagcgta ggatttggca atagcaaatc caattccata agaagcgccg gtgatgagag
    27361 caatttttcc ttttaaagaa aactgctcaa ttgagaatga tgtatttgtc atttgatact
    27421 tcctttcaaa tttgttaaga cttctctata accaaattat attctagtaa accggttttg
    27481 tcaataaata aatatttt
//
LOCUS       DBEJJV010000028        26289 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.028, whole genome shotgun sequence.
ACCESSION   DBEJJV010000028 DBEJJV010000000
VERSION     DBEJJV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 26289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.028"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..899
                     /gene="lytB"
                     /locus_tag="ACL3GT_001382"
     CDS             <1..899
                     /gene="lytB"
                     /locus_tag="ACL3GT_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGR0517043.1"
                     /translation="KNETVDGYQLGSDGKWLGGKTTNENAAYYQVVPVTANVYDSDGE
                     KLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGH
                     RFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAE
                     ELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNN
                     FFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASD
                     PYWGEKIASVMMKINEKLGGKD"
     gene            complement(960..2615)
                     /gene="pavA"
                     /locus_tag="ACL3GT_001383"
     CDS             complement(960..2615)
                     /gene="pavA"
                     /locus_tag="ACL3GT_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HGR0517044.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIGLDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2720..3217
                     /gene="ybeY"
                     /locus_tag="ACL3GT_001384"
     CDS             2720..3217
                     /gene="ybeY"
                     /locus_tag="ACL3GT_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HGR0517045.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHKLNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3198..3593
                     /locus_tag="ACL3GT_001385"
     CDS             3198..3593
                     /locus_tag="ACL3GT_001385"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HGR0517046.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3610..4509
                     /gene="era"
                     /locus_tag="ACL3GT_001386"
     CDS             3610..4509
                     /gene="era"
                     /locus_tag="ACL3GT_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HGR0517047.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4558..5382
                     /gene="mutM"
                     /locus_tag="ACL3GT_001387"
     CDS             4558..5382
                     /gene="mutM"
                     /locus_tag="ACL3GT_001387"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HGR0517048.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5382..5987
                     /gene="coaE"
                     /locus_tag="ACL3GT_001388"
     CDS             5382..5987
                     /gene="coaE"
                     /locus_tag="ACL3GT_001388"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HGR0517049.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5974..7173
                     /locus_tag="ACL3GT_001389"
     CDS             5974..7173
                     /locus_tag="ACL3GT_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HGR0517050.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7173..7322
                     /gene="rpmG"
                     /locus_tag="ACL3GT_001390"
     CDS             7173..7322
                     /gene="rpmG"
                     /locus_tag="ACL3GT_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0517051.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7362..7595
                     /gene="secG"
                     /locus_tag="ACL3GT_001391"
     CDS             7362..7595
                     /gene="secG"
                     /locus_tag="ACL3GT_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HGR0517052.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7697..10051
                     /gene="rnr"
                     /locus_tag="ACL3GT_001392"
     CDS             7697..10051
                     /gene="rnr"
                     /locus_tag="ACL3GT_001392"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HGR0517053.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNH
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYVDVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10014..10481
                     /gene="smpB"
                     /locus_tag="ACL3GT_001393"
     CDS             10014..10481
                     /gene="smpB"
                     /locus_tag="ACL3GT_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HGR0517054.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10497..11357
                     /gene="tehB"
                     /locus_tag="ACL3GT_001394"
     CDS             10497..11357
                     /gene="tehB"
                     /locus_tag="ACL3GT_001394"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0046690 - response to tellurium ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HGR0517055.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11430..12383
                     /gene="coiA"
                     /locus_tag="ACL3GT_001395"
     CDS             11430..12383
                     /gene="coiA"
                     /locus_tag="ACL3GT_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HGR0517056.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12402..14204
                     /gene="pepF"
                     /locus_tag="ACL3GT_001396"
     CDS             12402..14204
                     /gene="pepF"
                     /locus_tag="ACL3GT_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HGR0517057.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14206..14919
                     /locus_tag="ACL3GT_001397"
     CDS             14206..14919
                     /locus_tag="ACL3GT_001397"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HGR0517058.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14986..15927
                     /gene="prsA"
                     /locus_tag="ACL3GT_001398"
     CDS             14986..15927
                     /gene="prsA"
                     /locus_tag="ACL3GT_001398"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HGR0517059.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16044..16385)
                     /locus_tag="ACL3GT_001399"
                     /pseudo
     CDS             complement(16044..16385)
                     /locus_tag="ACL3GT_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16799..16894
                     /locus_tag="ACL3GT_001400"
                     /pseudo
     CDS             16799..16894
                     /locus_tag="ACL3GT_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(17148..17768)
                     /locus_tag="ACL3GT_001401"
     CDS             complement(17148..17768)
                     /locus_tag="ACL3GT_001401"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0517060.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(17768..18250)
                     /locus_tag="ACL3GT_001402"
     CDS             complement(17768..18250)
                     /locus_tag="ACL3GT_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HGR0517061.1"
                     /translation="MAKKVKIKKTLAEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(18250..19092)
                     /locus_tag="ACL3GT_001403"
     CDS             complement(18250..19092)
                     /locus_tag="ACL3GT_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HGR0517062.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDFLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(19187..19987)
                     /locus_tag="ACL3GT_001404"
     CDS             complement(19187..19987)
                     /locus_tag="ACL3GT_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HGR0517063.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            20131..21510
                     /gene="glmU"
                     /locus_tag="ACL3GT_001405"
     CDS             20131..21510
                     /gene="glmU"
                     /locus_tag="ACL3GT_001405"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002899862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HGR0517064.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            21520..22065
                     /locus_tag="ACL3GT_001406"
     CDS             21520..22065
                     /locus_tag="ACL3GT_001406"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0517065.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            22077..22391
                     /gene="macP"
                     /locus_tag="ACL3GT_001407"
     CDS             22077..22391
                     /gene="macP"
                     /locus_tag="ACL3GT_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HGR0517066.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            22408..23100
                     /locus_tag="ACL3GT_001408"
     CDS             22408..23100
                     /locus_tag="ACL3GT_001408"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HGR0517067.1"
                     /translation="MKIGIIAAMPEELAYLVQHLYNVQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLAFLKALD"
     gene            23177..23668
                     /gene="rocS"
                     /locus_tag="ACL3GT_001409"
     CDS             23177..23668
                     /gene="rocS"
                     /locus_tag="ACL3GT_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HGR0517068.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            23766..24356
                     /locus_tag="ACL3GT_001410"
     CDS             23766..24356
                     /locus_tag="ACL3GT_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HGR0517069.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            24365..26128
                     /locus_tag="ACL3GT_001411"
     CDS             24365..26128
                     /locus_tag="ACL3GT_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HGR0517070.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASFFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         7992 a         4783 c         5755 g         7759 t
ORIGIN      
        1 cgaaaaatga gacagtagat ggttatcagc ttggaagcga tggtaaatgg cttggaggaa
       61 aaactacaaa tgaaaatgct gcttactatc aagtagtgcc tgttacagcc aatgtttatg
      121 attcagatgg tgaaaagctt tcctatatat cgcaaggtag tgtcgtatgg ctagataagg
      181 atagaaaaag tgatgacaag cgcttggcta ttactatttc tggtttgtca ggctatatga
      241 aaacagaaga tttacaagcg ctagatgcta gtaaggactt tatcccttat tatgagagtg
      301 atggccaccg tttttatcac tatgtggctc agaatgctag tatcccagta gcttctcatc
      361 tttctgatat ggaagtaggc aagaaatatt attcggcaga tggcctgcat tttgatggtt
      421 ttaagcttga gaatcccttc cttttcaaag atttaacaga ggctacaaac tacagtgctg
      481 aagaattgga taaggtattt agtttgctaa acattaacaa tagccttttg gagaacaagg
      541 gcgctacttt taaggaagcc gaagaacatt accatatcaa tgccctttat ctccttgccc
      601 atagtgccct agaaagtaac tggggaagaa gtaaaattgc caaagataag aataatttct
      661 ttggcattac agcctatgat acgacccctt acctttctgc taagacattt gatgatgtgg
      721 ataagggaat tttaggtgca accaagtgga ttaaggaaaa ttatatcgat aggggaagaa
      781 ctttccttgg aaacaaggct tctggtatga atgtggaata tgcttcagac ccttattggg
      841 gcgaaaaaat tgctagtgtg atgatgaaaa tcaatgagaa gctaggtggc aaagattagt
      901 actataagtg aatatgattt gagtgaatag taagttaaaa atcctgattt caagtaaaat
      961 caggattttt tcatggatgc aatttttttg gagtctggtg tgacgcggag ggtcttttgt
     1021 cctgtgtaag tgacaaagcc gggttttcca ccagttggtt tattgagttt tttgacttca
     1081 atcatatcta cctgcaccag attcgacagg cgcccttgag agaagtaggc agctaactct
     1141 gctgcgtctg tcttgactgc atcagatggg tcaagatttc ctgagatgac aacatggctt
     1201 ccaggaatgt ccttagcatg gaaccaaagt tcctccttgc gggccatttt aaaggtcaat
     1261 tcctcatttt gaagattgtt tcgtccgaca tagatgatgg ttttgccatc gcttgctaga
     1321 tattgttcta gttttttgcg tttctggatt ttctcccgtt gtcttctgcg gataaaacct
     1381 gtttgaatca attcttcacg gatttcagcg atttcttcca gtccagcttg gttgaggacg
     1441 gtttctacac tttccagata gagaatagtg gctttggttt cttcaatcaa atcagtcaag
     1501 tatttgacag cttctttgag tttctgatac cgtttaaaat agcgttgggc attctggttg
     1561 ggagtcagag ccttatcaag cccaatcatg ataggttggt tggtatagta gttgtctagg
     1621 ataacctggt cttggtcgtt aggcacttgg tggaggaagg ttgtcagcaa ttctcctttt
     1681 tgacgaaatt cttcagcgtt gtctgtcgcc agtaattctt tttcctgttt tttgagtttg
     1741 tgtcggtttt tctgaagttc attttcaaca cgacgaatca gttcactggc ctgctgtttg
     1801 acgcggtcgc gctcagcctt atccttatag taggtgtcca acaaatcaga aagatttgca
     1861 aaaggctctc ccacctgatt tgcaaaagga actggactga aggaagtctc agtcaagcat
     1921 ggcttggttt cctgattgaa aaaatttcgg aaagcggaaa gtttttcact aaccagtatc
     1981 ctttccaatt catttgccgt atcgcgtccc agaccttgaa agaggctttg aagatttttt
     2041 gctgttagtt cttgggtttg caggatttca aagagctttt catccttgat agtaaaagga
     2101 ttgagagatt ctgtacttgg cggagcgata taggtcgatc ctggaagtaa ggtgcggtag
     2161 ctattttgtg aaaagccgac gtgtttgata acttcgagga ttttatgact gcttttatcg
     2221 accagtagaa tattactgtg tttccccata atttcgataa tcaaggtagc ctggatatgg
     2281 tctccaatct cgtttttatt ggaaactgtc atttccacaa tacggtcatt ttccacttgc
     2341 tcaatcgact caatcagggc cccctgcaaa tactttctca aaaccatgat aaaggtagaa
     2401 ggttgggctg gattttcaaa agtcgtttgg gtcagctgaa tgcgtccaaa aactggatgg
     2461 gcagaaagga gcaggcgatg gctttggcga ttgctgcgga tttgcaagac caactcttgt
     2521 tcaaaaggct gattgatttt ctggatgcga ccattcacta attcgcttcg caattcctca
     2581 actatgtggt gtaaaaaaaa tccgtcaaat gacatcgttc tctccttgtg attgtattcc
     2641 atagtattat atcaaaaagg tagaataaaa tcatggaaat gtggtataat aaagccaagt
     2701 aaagagaaac gagaagcaca tgtatattga aatggtagat gaaactggtc aagtttcaaa
     2761 agaaatgttg caacaaaccc aagaaatttt ggaatttgca gccaaaaaat taggaaaaga
     2821 agacaaggag atggcagtca cttttgtgac caatgagcgt agtcataaac ttaatctgga
     2881 gtaccgtgac accgaccgtc cgacagatgt catcagcctt gagtataaac cagaattgga
     2941 aattgccttt gacgaagagg atttgcttga aaatccagaa ttggcagaga tgatgtctga
     3001 gtttgatgcc tatattgggg aattgttcat ctctatcgat aaggctcatg agcaggccga
     3061 agaatatggt cacagctttg agcgtgagat gggcttcttg gcagtacacg gctttttaca
     3121 tattaacggc tatgatcact atactccgga agaagaagcg gagatgttcg gtttacaaga
     3181 agaaattttg acagcctatg gactcacaag acaataaacg aaaatggaaa aatcgtgacc
     3241 tgatatccag tttagaattt gccatcacag ggatttttac tgctatcaag gaagaacgca
     3301 atatgcgaaa acatgcagtg acggctctag tggtcatcct tgcaggtttt ggttttcagg
     3361 tgtcacgaat cgaatggctc tttctcctat tgagcatttt cttggtggta gcctttgaaa
     3421 ttatcaattc tgctattgaa aatgtggtgg atttggccag tcactatcac ttttccatgc
     3481 tggctaaaaa tgccaaggat atggcggctg gcgcggtatt agtggtttct ctttttgcag
     3541 ccttaacagg cgcattgatt tttctcccac gaatctggga tttattattt taaacagtaa
     3601 gaggaaatta tgacttttaa atcaggcttt gtagccattt taggacgtcc caatgttggg
     3661 aagtcaacct ttttaaatca cgttatgggg caaaagattg ccatcatgag tgacaaggcg
     3721 cagacaacgc gcaataaaat catgggaatt tacacgactg ataaggagca aattgtcttt
     3781 atcgacacac cagggattca caaacctaaa acagctctcg gagatttcat ggttgagtct
     3841 gcctacagta cccttcgcga agtggacact gttcttttca tggtgcctgc tgatgaagcg
     3901 cgtggtaagg gggacgatat gattatcgag cgtctcaagg ctgccaaggt tcctgtgatt
     3961 ttggtggtga ataaaatcga taaggtccat ccagaccagc tcttgtctca gattgatgac
     4021 ttccgtaatc aaatggactt taaggaaatt gttccaatct cagcccttca gggaaataac
     4081 gtgtctcgtc tagtggatat tttgagtgaa aatctggatg aaggtttcca atatttcccg
     4141 tctgatcaaa tcacagacca tccagaacgt ttcttggttt cagaaatggt tcgcgagaaa
     4201 gtcttgcact taactcgtga agagattccg cattctgtag cagtagttgt tgactctatg
     4261 aaacgagacg aagagacaga caaggttcac atccgtgcaa ccatcatggt cgagcgcgat
     4321 agccaaaaag ggattatcat cggtaaaggt ggcgctatgc ttaagaaaat cggtagcatg
     4381 gcccgtcgtg atatcgaact catgctagga gacaaggtct tcctagaaac ctgggtcaag
     4441 gtcaagaaaa actggcgcga taaaaagcta gatttggctg actttggcta taatgaaaga
     4501 gaatactaag tagaggtagg ctcatgcctg cttcttgttt ttacagaagg aggacttatg
     4561 cctgaattac ctgaggttga aaccgtttgt cgtggcttag aaaaattgat tataggaaag
     4621 aagatttcga gtatagaaat tcgctacccc aagatgatta agacggattt ggaagagttt
     4681 caaagggaat tgcctagtca gattatcgag tcaatgggac gtcgtggaaa atatttgctt
     4741 ttttatctga cagacaaggt cttgatttcc catttgcgga tggagggcaa gtatttttac
     4801 tatccagacc aaggacctga acgcaagcat gcccatgttt tctttcattt tgaagatggt
     4861 ggcacgcttg tttatgagga tgttcgcaag tttggaacca tggaactctt ggtgcctgac
     4921 cttttagacg cctactttat ttctaaaaaa ttaggtcctg aaccaagcga acaagacttt
     4981 gatttacagg tctttcaatc tgcccttgcc aagtccaaaa agcctatcaa atcccatctc
     5041 ctagaccaga ccttggtagc tggacttggc aatatctatg tggatgaggt tctctggcga
     5101 gctcaggttc atccagctag accttcccag actttgacag cagaagaagc gactgccatt
     5161 catgaccaga ccattgctgt tttgggccag gctgttgaaa aaggtggctc caccattcgg
     5221 acttatacca atgcctttgg ggaagatgga agcatgcagg actttcatca ggtctatgat
     5281 aagactggtc aagaatgtgt acgctgtggt accatcattg agaaaattca actaggtgga
     5341 cgtggaaccc acttttgtcc aaactgtcaa aggagggact gatgggaaaa atcatcggaa
     5401 tcactggggg aattgcctca ggtaagtcaa ctgtgacaaa ttttctaaga cagcaaggct
     5461 ttcaagcagt ggatgccgac gcagtcgtcc accaactaca gaaacctggt ggtcgtctgt
     5521 ttgaggctct agtacagcac tttgggcaag aaatcattct tgaaaacgga gaactcaatc
     5581 gccctctcct agctagtctc atcttttcaa atcctgaaga gcaaaaatgg tctaatcaaa
     5641 ttcaagggga gattatccgt gaggaactgg ctactttgag agaacagttg gctcagacag
     5701 aagagatttt cttcatggat attcccctac tttttgagca ggactacagc gattggtttg
     5761 ctgagacttg gttggtctat gtggaccgag atgcccaagt agaacgctta atgaaaaggg
     5821 accagttgtc caaagatgaa gctgagtctc gtctggcagc ccagtggcct ttagaaaaaa
     5881 agaaagattt ggccagccag gttcttgata ataatggcaa tcagaaccag cttcttaatc
     5941 aagtgcatat ccttcttgag ggaggtaggc aagatgacag agattaactg gaaggataat
     6001 ctgcgtattg cctggtttgg taattttctg acaggagcca gtatttcttt ggttgtacct
     6061 tttatgccca tcttcgtgga aaatctaggt gtagggagtc agcaagtcgc tttttatgca
     6121 ggcttagcaa tttctgtctc tgctatttcc gcggcgctct tttctcctat ttggggtatt
     6181 cttgctgaca aatacggccg aaaacccatg atgattcggg caggtcttgc tatgactatc
     6241 actatgggag gcttggcctt tgtcccaaat atctattggt taatctttct tcgtttacta
     6301 aacggtgtat ttgcaggttt tgttcctaat gcaacggcac tgatagccag tcaggttcca
     6361 aaggagaaat caggctctgc cttaggtact ttgtctacag gcgtagttgc aggtactcta
     6421 actggtccct ttattggtgg ctttattgca gaattatttg gcattcgtac agttttctta
     6481 ctggttggta gttttctatt tttagctgct attttgacta tttgctttat caaggaagat
     6541 tttcaaccag tagccaagga aaaggctatt ccaacaaagg aattatttac ctcggttaaa
     6601 tatccctatc ttttgctcaa tctcttttta accagttttg tcatccaatt ttcagctcaa
     6661 tcgatcggcc ctattttggc tctttatgta cgcgacttag ggcagacaga gaatcttctt
     6721 tttgtctctg gtttgattgt gtccagtatg ggcttttcca gtatgatgag tgcaggagtc
     6781 atgggcaagc taggtgacaa ggtgggcaat catcgtctct tggttgtcgc ccagttttat
     6841 tcagtcatca tctatctcct ctgtgccaat gcctctagcc cccttcaact aggactctat
     6901 cgtttcctct ttggcttggg aaccggtgcc ttgattcccg gggttaatgc cctactcagc
     6961 aaaatgactc ccaaagccgg catttcgagg gtctttgcct ttaatcaggt attcttttat
     7021 ctgggaggtg ttgttggtcc catggcaggt tctgcagtag caggtcaatt tggctaccat
     7081 gctgtctttt atgcgacaag cctttgtgtt gcctttagtt gtctctttaa cctgattcaa
     7141 tttcgaacat tattaaaagt aaaggaaatc tagtgcgagt aaaaattaat ctcaaatgct
     7201 cctcttgtga cagtatcaat tacctaacca gtaaaaattc aaaaacccat ccagacaaga
     7261 ttgaggtttt aaagtattgt cccaaggaaa gaaaagtaac cctacatctt gaatctaagt
     7321 agattttatg gtaaaataat agggatttta aggagtttga tatgtataac ctattattaa
     7381 ccattttatt agtattatct gttgtgattg tgattgcaat tttcatgcaa ccaaccaaaa
     7441 accaatccag caatgtattt gatgccagtt caggtgattt gtttgaacgc agtaaagctc
     7501 gcggttttga agctgtaatg cagcgtttga cagggatttt agtctttttc tggctagcca
     7561 ttgccttagc attgacggta ttatcaagta gataagaaaa taatgggcag gactaggtct
     7621 ttgcctcttt ttatttttaa aggatgtttg agaaggtttt acagtaaaag aaaattaaaa
     7681 aatctagaaa gaaaatatga aagatagaat aaaagaatat ttacaagaca agggaaaggt
     7741 gactgttaat gatttggctc aggctttggg aaaagacagt tccaaggatt ttcgtgagtt
     7801 gattaaaacc ttgtccttaa tggaaagaaa gcaccagatt cgctttgaag aagatggtag
     7861 tctgacatta gaaattaaga aaaaacatga gattaccctc aaggggattt ttcatgccca
     7921 taaaaatggc tttggctttg ttagtctgga aggcgaggag gacgaccttt ttgtagggaa
     7981 aaatgatgtc aactatgcta ttgatggtga taccgtcgag gtagtgatta agaaagtcgc
     8041 tgaccgcaat aagggaacag cagcagaagc caaaattatt gatatcctag aacacagttt
     8101 gacaacagtt gtcgggcaaa tcgttctgga tcaggaaaag cctaagtatg ctggctatat
     8161 tcgttcaaaa aatcataaaa tcagtcaacc gatttatgtt aagaaaccag ccctaaaatt
     8221 agaaggaaca gaagttctca aagtctttat cgataaatac ccaagcaaga aacatgattt
     8281 ctttgtcgct agtgtactcg atgtagtggg acactcaacg gatgtcggaa ttgatgttct
     8341 tgaggtcttg gaatcaatgg acattgtatc tgagtttcca gaagctgttg tcaaggaagc
     8401 agaaagtgtg cctgatgctc cgtctcaaaa ggatatggaa ggtcgtctgg atctaagaga
     8461 tgaaattacc tttaccattg acggtgcgga tgccaaggac ttagacgatg cagtgcatat
     8521 caaggctctg aaaaatggca atctggagct tggggttcac atcgcagatg tttcctatta
     8581 tgtgaccgag gggtctgccc ttgacaagga agcccttaac cgtgcgactt ctgtttacgt
     8641 gacagaccga gtggtgccaa tgcttccaga acgactatca aatggcatct gctctctcaa
     8701 tccccaagtt gaccgcctga cccagtctgc tattatggag attgataaac atggtcgtgt
     8761 ggtcaactat accattacac aaacagttat caagaccagt tttcgtatga cctatagcga
     8821 tgtcaatgat atcctagctg gcgatgaaga aaagagaaaa gaatatcata aaattgtacc
     8881 aagtatcgaa ctcatggcca agcttcatga aactttagaa aacatgcgtg tgaaacgtgg
     8941 agctctcaat tttgatacca atgaagcgaa gattttagtg gataaacaag gtaagcctgt
     9001 tgatatcgtt cttcggcagc gtggcattgc cgagcggatg attgagtctt ttatgttgat
     9061 ggctaatgaa acagttgccg aacatttcag caagttggat ttgcctttta tctatcgaat
     9121 tcacgaggag cctaaggctg aaaaggttca gaagtttatt gattatgctt cgagttttgg
     9181 cttgcgcatt tatgggactg ccagtgagat tagtcaggag gcacttcaag acatcatgcg
     9241 tgctgttgag ggagaacctt atgtagatgt attgtccatg atgcttcttc gctctatgca
     9301 gcaggctcgt tattcggagc acaatcacgg ccactatgga ctagctgctg actattatac
     9361 tcactttacc agtccaattc gtcgttatcc agaccttctt gttcaccgta tgattcggga
     9421 ttacggctgt tctaaggaaa tagcagagca ttttgaacaa gtgattccag agattgcgac
     9481 ccagtcttcc aaccgtgaac gtcgtgccat agaagctgag cgtgaagtcg aagccatgaa
     9541 aaaggctgag tatatggaag aatacgtggg tgaagagtat gatgcagttg tatcaagtat
     9601 tgtcaaattc ggtctctttg tcgaattgcc aaacacagtt gaaggcttga ttcacatcac
     9661 taatctacct gaattttatc atttcaatga gcgtgatttg actcttcgtg gagaaaaatc
     9721 aggtatcact ttccgagtgg gtcagcagat ccgtatccgt gttgaaagag cggataaaat
     9781 gactggagag attgattttt cattcgtacc tagtgagttt gatgtgattg aaaaaggctt
     9841 gaaacagtct agtcgtagtg gcagagggcg tggttcaaat cgtcgttcgg ataagaagga
     9901 agacaagaga aaatcaggac gctcaaatga taagcgtaag cattcacaaa aagacaagaa
     9961 gaaaaaagga aagaaacctt tttacaagga agtagctaag aaaggagcca agcatggcaa
    10021 agggcgaggg aaaggtcgtc gcacaaaata aaaaggcacg ccacgactat acaatcgtag
    10081 atacgctaga ggcagggatg gtcctgactg gaactgaaat caagagtgta cgagctgctc
    10141 gaattaatct caaggatggc tttgctcaag tgaaaaatgg agaagtttgg ctgagcaatg
    10201 ttcatatcgc gccttacgaa gagggcaata tctggaacca ggaaccagaa cgtcgtcgta
    10261 aactcctgct ccataaaaag caaattcaaa aattggaaca agagaccaaa gggacaggaa
    10321 tgaccttagt tccccttaag gtctatataa aagatggcta cgctaagctt cttttaggac
    10381 ttgccaaagg gaagcatgac tatgacaaac gggagtctat caaacgtcgt gagcaaaatc
    10441 gagatatcgc gcgtgtgatg aaagctgtta atcagcgata aaaagaggaa ttgaaaatgg
    10501 aaaaattagt tgcctataaa cgcatgcctt tgtggaataa acaaacaatg cctgaagctg
    10561 ttcagcaaaa gcacaataca aaagttggga cttgggggaa aattactgtc ttgaagggag
    10621 ctctcaagtt tattgaattg acagaagaag gggaagttct agctgaacac ctctttgaag
    10681 caggggcaga caatccaatg gcccaacctc aagcctggca ccgagtggaa gctgccacag
    10741 atgatgtgga atggtacttg gaattttatt gtaaacctga ggattatttt gctaaaaaat
    10801 acaataccaa tcctgttcat tcagaggtcc tagaggccat gcagacagtg aaacaaggga
    10861 aagctttgga tttgggttgt ggtcaggggc gtaattctct ttttctagcc cagcaagatt
    10921 ttgatgtgac ggctgtagat caaaatggac tagctcttga aatcttgcaa agcattgtgg
    10981 agcaggaaga tttggacatg cctgttggcc tttacgatat caattcagct agcattgaac
    11041 aagaatatga ttttatcgtt tcaacagttg ttctcatgtt tctacaagcg gaccgcattc
    11101 cagctattat tcaaaatatg caggagaaaa ccagtgttgg cggttacaac cttatcgttt
    11161 gtgccatgga cacggaggat tatccttgct cggttaactt cccattcacc tttaaagaag
    11221 gagaactggc agactattac aaggattggg aattggttaa gtacaatgaa aatccaggcc
    11281 atttgcaccg tcgcgatgag aatggcaatc gtattcaact acgctttgcg accttactag
    11341 ctaagaaaat caagtaaaca cacatgaaga ttaggaattt tcctgatctt ttttcttttt
    11401 tacgaatgat atagaaaagg agggaattca tgtttgttgc gagagatgct aggggagaat
    11461 tggtaaatgt gttagaggat aaacttgaga agcaagcata cacctgccca gcttgtggag
    11521 gccagctcca tttgcgtcaa ggaccaagtg tacggacgca ttttgcccat aaatccttaa
    11581 aagactgtga ttttttcttt gaaaatgaaa gtccagaaca cctggccaat aaggaatccc
    11641 tctatcactg gttgaaaaaa gagacaaagg ttcaattaga gtacccgctt tcagaactta
    11701 aacagattgc ggatgtattt gtaaatggca atctagctct agaagttcag tgtagtccct
    11761 tgcctcagaa agtccttaaa gagcgaagtg agggctatcg tagtcagggt taccaagtac
    11821 tgtggttgct gggtcaaaaa ctgtggctca aggagcgttt gactcgtcta cagcaaggtt
    11881 ttctttattt cagtcaaaac atgggctttt atgtttggga attagacaag gaaaaacaag
    11941 ttttaagact caaatacctg atttaccagg atctccgcgg taaactccat tatcaaatca
    12001 aggaattttc ctatggtcaa ggtagtttat tggaaatatt gcgtcttccc tataagagac
    12061 aaaaaatatc tcattttaca gtttctgagg acaaggacat ctgtcgctat atccggcaac
    12121 aactttatta tcaaaatctc ttttggatga aagaacaagc agaagcctat caaaagggag
    12181 aaaatatcct gacttatgga ctgaaagaat ggtatccaca aattcgacca atagtgggca
    12241 aatttttcca gattgaacaa gacttgacta gctattatca gcacttttat acctattacc
    12301 aaaaaaatcc tcaaaatgat tggcaaaagc tttatccacc agccttttat cagcaatatt
    12361 tcttgaaaaa tatggtagaa tagaaaggat ggaggaatct aatggtatta caaagaaatg
    12421 aaataaatga aaaagataca tgggatctat caacgatcta cccaactgac caggcttggg
    12481 aagaagcctt aaaagattta acagaacaat tggagacagt agcccagtat gaaggccatc
    12541 tcttggatag tgcggataac ctactagaaa tcactgaatt ttctcttgaa atggaacgcc
    12601 agatagagaa gctttacgtt tatgctcata tgaagaatga ccaggataca cgtgaagcta
    12661 agtatcaaga gtactatgcc aaggccatga cactctacag ccagttagac caagcctttt
    12721 cattctatga gcctgaattt atggagatta gcgaaaagca gtatgctgac tttttagaag
    12781 ctcaaccaaa gctgcaggtt tatcaacact attttgacaa gctcttgcaa ggcaaggatc
    12841 acgttctttc acaacgtgaa gaagaattat tggctggagc tggagaaatc tttggttcag
    12901 caagtgaaac cttcgctatc ttggacaatg cggatattgt gttcccttat gtcctagacg
    12961 atgatggtaa agaagttcag ctatctcatg ggacttacac acgtttgatg gagtctaaaa
    13021 aacgtgaggt tcgccgtggt gcctatcaag ctctttatgc tacttacgaa caattccaac
    13081 acacctatgc caaaaccttg caaaccaatg ttaaggtgca aaattaccgt gctaaagttc
    13141 gtaactacaa gagtgctcgt catgcagccc tcgcagcgaa ttttgttcca gaaagtgttt
    13201 atgacaattt ggtagcagca gttcgcaagc atttgccact cttacatcgc tatcttgagc
    13261 ttcgttcaaa aatcttgggg atttcagatc tcaagatgta cgatgtctac acaccgcttt
    13321 catctgttga atacagtttt acctaccaag aagccttgaa aaaagcagaa gatgctttgg
    13381 cagtcttggg tgaggattac ttgagccgtg ttaaacgtgc cttcagcgag cgttggattg
    13441 atgtttacga aaatcaaggc aagcgttcag gtgcctactc tggtggttct tacgatacca
    13501 atgcctttat gcttctcaac tggcaggaca atctggacaa tctctttact cttgttcatg
    13561 aaacaggtca cagtatgcat tcaagctata ctcgtgaaac tcagccttat gtttacgggg
    13621 attactctat ctttttggct gagattgcct caactaccaa tgaaaatatc ttgacggaga
    13681 aattattgga agaagtggaa gacgacgcaa cacgctttgc tattctcaat aacttcctag
    13741 atggtttccg tggaacagtt ttccgccaaa ctcaatttgc tgagtttgaa cacgccattc
    13801 accaagcaga tcaaaatggg gaggtcttga caagcgattt cctaaataaa ctctacgcag
    13861 acttgaacca agagtattat ggtttgagta aggaagacaa tcctgaaatc caatacgagt
    13921 gggctcgcat tccacacttc tactataact actatgtata tcaatattca actggctttg
    13981 cggccgcctc agccttggct gaaaaaattg tccatggtag tcaagaagac cgtgaccgct
    14041 atatcgacta cctcaaggca ggtaagtcgg actatccact taatgtcatg agaaaagctg
    14101 gtgttgatat ggagaaggaa gactacctca acgatgcctt tgcagtcttt gaacgccgtt
    14161 taaatgagtt tgaagccctt gttgaaaaat taggattggc ataaaatggt tgaatcgtat
    14221 agtaagaatg ctaaccataa catgcgtcgt cctgtcgtca aagaagaaat tgtagacttg
    14281 atgcgtcagc gtcaaaagca ggtcacaggt ttcttgaaag aattggaaga ctttgcccgc
    14341 aaggaaaata ttcctattat tccccatgaa acggttgctt atttccgttt tcttatggaa
    14401 accatgcagc ctaaaaatat tctggaaatt gggacggcta tcggtttttc agctctcttg
    14461 atggctgaac atgcgccaaa tgctaagatt acaactattg atcgtaatcc agaaatgatt
    14521 ggttttgcca aggaaaattt tgcccagttt gacagtcgca agcaaatcac tctcctagag
    14581 ggagatgcgg tggatgtctt atctacactg acagagtctt atgatttcgt atttatggat
    14641 tctgccaagt ctaaatacat cgtctttctg ccagaaatcc tcaaacattt ggaagttggt
    14701 ggtgtggttg tcttggatga tatttttcaa ggtggtgatg ttgccaagga tattatggaa
    14761 gtccgtcgtg gtcagcgaac catttatcga ggccttcaaa aattatttga tgcaacctta
    14821 gacaatccag aactcaccgc aacattagtg cctttaggag atggtattct catgcttcgt
    14881 aaaaatgtag cagatgttca actgtctgaa agcgaatgat tttcagaaaa atttaagaaa
    14941 aaatagtaaa atagatagag taacacttat ctcaaaggag tagacatgaa gaaaaaatta
    15001 ttggcaggtg ccatcacact attatcagta gcaactttag cagcttgttc gaaagggtca
    15061 gaaggagcag accttatcag catgaaaggg gatgtcatca cagaacatca attttatgag
    15121 caagtgaaaa acaacccttc agcccaacaa gtcttgttaa atatgaccat ccaaaaagtt
    15181 tttgaaaaac aatatggctc agagcttgat gataaagagg ttgatgatac tattgccgaa
    15241 gaaaaaaaac aatatggcga aaactaccaa cgtgtcttgt cacaagcagg tatgactctt
    15301 gaaacacgta aagctcaaat tcgtacaagt aaattagttg agttggcagt taagaaggta
    15361 gcagaagctg aattgacaga tgaagcctat aagaaagcct ttgatgagta cactccagat
    15421 gtaacggctc aaatcatccg tcttaataat gaagataagg ccaaagaagt tctcgaaaaa
    15481 gccaaggcag aaggtgctga ttttgctcaa ttagccaaag ataattcaac tgatgaaaaa
    15541 acaaaagaaa atggtggaga aattaccttt gattctgctt caacagaagt acctgagcaa
    15601 gtcaaaaaag ccgctttcgc tttagatgtg gatggtgttt ctgatgtgat tacagcaact
    15661 ggcacacaag cctacagtag ccaatattac attgtaaaac tcactaagaa aacagaaaaa
    15721 tcatctaata ttgatgacta caaagaaaaa ttaaaaactg ttatcttgac tcaaaaacaa
    15781 aatgattcaa catttgttca aagcattatc ggaaaagaat tgcaagcagc caatatcaag
    15841 gttaaggacc aagccttcca aaatatcttt acccaatata tcggtggtgg agattcaagc
    15901 tcaagcagta gtacatcaaa cgaatagtcc aaatcaatga gtcagggaaa aaactctact
    15961 tcaggaaaaa atgaagcaaa cattcccaca ataaaacgcg tagtacaagg tttgtactga
    16021 cccccaaaag ttagacaaat aatttatccg aaggatttag ttctgtattg cacagggcta
    16081 agtcctttta gttttacctt aattctcttg ttgttgtaat aatcaatata gtatataatg
    16141 gcttgttcca attgattaag tgatttaaat gttttctcat agccataaaa catttcggat
    16201 tttaaaatac caaagaaaga ttccatccta ccgttgtctt ggctgtttcc cttgcgtgac
    16261 atagatgctt gaattccctt actctctagg aaccgatgat aagaatcgtg ttggtattgc
    16321 cagtcttggt cactatggag aatcgtattc tcgtagtgct tctctttgaa tgcctgttcc
    16381 aacattaacg atcaatcaat ttaatcatgt acctaatatt agaattgttt atctcaaatt
    16441 tatttgaaag cttctctaag ctatatcctt gttttctaag ttcatagatc tgaactttat
    16501 catcataagt taatttcata ataaaaacac tccaaaagtt agattttttc tgtctaactt
    16561 ttggggtgca gttcatttaa cacctgataa tatgcgtttt ttttatttta aagacttttt
    16621 gaccagcctc attttttaac ttgatactca gtgaaaagca aagattaaac taggaagcta
    16681 gctgtaggct gctcaaagaa cagctttgag gttgcagata aaacttgtga ggtaaccaac
    16741 atatataatg tgaagctgac gtggtttgaa tagattttag aagggtatga gtctggaagt
    16801 tttaatggat aatgcaagat tccatagaat gggtaagcta gagttcttat gtgaagagtt
    16861 tgggcataaa cttttacctt ttcctcccta ctcatcttag tatagaaaag tgaatctaaa
    16921 atagtacata actgcttcta aaacattctt ataaattgat ttaaattctc aaatcatatt
    16981 attcagttct tatttcattt tgctctacaa tcctgttgag aagacacgtg ttcatatcaa
    17041 aaaaggtatt ggcaagttgc aatacctttt tacgaggctc ttttatctta tttttgtttc
    17101 aactgactat atctcctatg gttctagttc agaaggctag gctataatta tgattgataa
    17161 gaagtatcat tccaagtatt gagagtgaat gtttcaaaat catgggtttc tataatggtc
    17221 aggctggcat ttgctagacc gccatcttta cgaagaagtg gttctttata gcctaggaga
    17281 gtacgaagac tggcagtaag attggcgccg tgtccgacaa ttagaatacg ttcagctgga
    17341 ctatctttta atgatttgat aaattggatg gtccgttgag ttgtactata gagggattcg
    17401 gctccgaaca ttcgagtgtc aaattgagca agatttgaac gaaaagcctg gatttgttgc
    17461 gggtaaatag cttccaaggt tgcaattttc aaaccttcta acttcccaag ttgccattca
    17521 cggagattag gaacgatttc taaagaacag ggggtataga gttgactttg gataatctca
    17581 gcagatttga ccgctcgagg taaatcactt gaataaatct gatcaaaagg aatttccttg
    17641 agatactgac caagtcgttt tagggtttca atggattcag gaagaagagg agaatcacca
    17701 ctagcacctt gaaaacgacc ttcttggttc cagagggtac gaccgtggcg gacaaagtag
    17761 agtttcatta cttgatgtcc tccaaaatat ctacaaagtc tgcctttaca aagctagcca
    17821 agtcttgtgg cgcgacgata atgctgtgtc cgacttcgcc tgcagagaca atcatttgat
    17881 ccaaatctag agcaatttta tcgataaaaa tgggataatt gtgtttctga cgaattccga
    17941 caggattatt ggctccatga atgtaaccag ttgttttttc taagtccttt tgtggaatca
    18001 tgctcacttt tttattgcca gaaattttag ctagtttctt ttcagacaag tgctgagtga
    18061 tagggacaat tccgataatc ggtccggtct tgtctcccaa aagcgccaag gttttgaaaa
    18121 tctgatctcg ttcataacct tgaggaagct ctccttctag ggcattgatt tgaatcccct
    18181 gatgagggat agctgcttta gataggattt gttccgccaa tgtttttttg attttaactt
    18241 tttttgccat tatttatatt tatcctccaa ttgactcatc caaataccaa gccagattcc
    18301 cagcgcaaag aagaaggcga tgatgacata accgacaagt gaaagtcctg tgtattggat
    18361 actttcagcg tttcctgcat ttggaattaa gatcaaaagg gtacttgata ggacgatacc
    18421 gatgatgaaa tgatagacac gtgagtggta gttgtttaag gcataatcca tcaattttga
    18481 aaaaacgatg agagttgcac ctgcaccaat tccaatcgga aagaaggttc ccaagaaatc
    18541 aaaagtttta aaaccagtca acataggagc atagagtccc aaaatcaaaa gtaaatttga
    18601 tgggctgagg ccaggaacca agacgccaag ggccaatagt gcgcctgcta ggacgaagtt
    18661 aagaaagctg gcgcttaagg ttccaacgac aaaatttaag gcatagagtc ctaatccaga
    18721 aatgataaag gttgtccata accaagctaa atcaatcttg tctcggtcag attctcgagt
    18781 tgattctttg aggaggctag gaactgtacc gataatagct cccgcaaagc tccataatac
    18841 aaaaacctga taattttcaa gcaggtattc aatcgggtag gaaaataagc cgattcccag
    18901 aagcataccg atggcaactg gaataaagta caaaacattt tctttaaagt ctttaaaggg
    18961 atgggccaga aagccaatca ttcgttcata gattcctaag attgctgcta gaacccctcc
    19021 ggaaattccc ggtaggataa atccaagagc aattacaatc cctttaataa cgcgtgctaa
    19081 ccatgagagc atatatttcc tccaactatt tctatttcaa aaaatcctta ctatattgta
    19141 tcacaatcag acacaaaaag aaaaagcaaa tgataaacaa atgcttttaa ggttttaaaa
    19201 aaagttttcg aaaggtttct tctttatttt ttaagggaga gataacgttg atatctaaat
    19261 cgtggtcaaa gccggcaatt tttcctttag atgtgtattg gtgaatatca taatctaaat
    19321 cagttttagg actgctctcc aaaaatcctg agtctgagcc gtaggacgga atccaaacag
    19381 aggtaaactt gcctgtatca atactgtgtt cttccatgaa gtagacacca acgtagatgc
    19441 cgatgttttt agcacctagt gatgctagtt ttgctcgaaa gttttcgaca ccttcgttca
    19501 tattagacat ggttttgtct tccacgtcaa gccaatagta actagggctg taaggagagg
    19561 cagcattgta gaaaacttcg gcagcctttt ccatttcttg gacacttttt ccagctacat
    19621 aagcgtagac agcaactggg acattccgct tttgaagttc agtgatatga ctcttatagg
    19681 ccttgtctat tccattgata aatgaagcat cattttcttt tgtcgtttga gcaccactgt
    19741 gaacacgaac aatagcacct gaaatatttt gtgagagggc atcgtagttg atttcttcag
    19801 gacgctgcca gccagagagg tcaataatcg gtttgtctaa gtgtttcaaa gcctgtgctt
    19861 caatctgtgc tatattggat tttgttttaa acgattggtt gtcattaagt gggcgattga
    19921 tgattaaaat gaacatcata atccccaaaa aactaaataa aataagtgga tgaatttgtt
    19981 ttctcatatc ttataattct accctaaaaa tcaaaaaaaa tcaaaaaaat gggttaagga
    20041 agagacttta gagcattttt tcattcaaga gtgcggaatg atttgaaata tggtataata
    20101 aaagggaatt tctacagaaa agagaagatt atgtcaaatt ttgccattat tttagcagcg
    20161 ggtaaaggga ctcgcatgaa atctgatttg ccaaaagttt tgcacaaggt tgcgggtatt
    20221 tctatgttgg aacatgtttt ccgtagtgtg ggagctatcc aacctgaaaa gacagtaaca
    20281 gttgtaggac acaaggcaga attggttgag gaggtcttgg ctggacagac agaatttgtg
    20341 actcaatctg aacagttggg aactggtcat gcagttatga tgacagaacc tatcttagaa
    20401 ggtttgtcag gacacacctt ggtcattgca ggagatactc ctttaatcac tggtgaaagc
    20461 ttgaaaaact tgattgattt ccatatcaat cataaaaatg tggccactat cttgactgct
    20521 gaaacggata atccttttgg ctatggacga attgttcgta atgacaatgc tgaggttctt
    20581 cgtattgttg agcagaagga tgctacagat tttgaaaagc aaatcaagga aatcaacact
    20641 ggaacatacg tctttgacaa cgagcgtttg tttgaggctt tgaaaaatat caataccaat
    20701 aacgctcaag gcgaatacta tattacagac gtcattggta ttttccgtga aactggtgaa
    20761 aaagttggcg cttatacttt gaaagatttt gatgaaagtc ttggggtaaa tgaccgtgtg
    20821 gcgcttgcga cagctgagtc agttatgcgt cgtcgcatca atcataaaca tatggtcaac
    20881 ggtgttagct ttgtcaatcc agaagcaact tatatcgata ttgatgttga gattgctccg
    20941 gaagttcaaa tcgaagccaa tgttaccttg aaagggcaaa cgaaaattgg tgctgagact
    21001 gttttgacaa acggtactta tgtagtggac agcactatcg gagcaggagc ggtcattacc
    21061 aattctatga ttgaggaaag tagtgttgca gacggtgtga cagtcggtcc ttatgctcac
    21121 attcgtccaa attcaagtct gggtgcccaa gttcatattg gtaactttgt tgaggtgaaa
    21181 ggatcttcaa tcggtgagaa taccaaggct ggtcatttga cttatatcgg aaactgtgaa
    21241 gtgggaagca acgttaattt cggtgctgga actattacag tcaattatga cggcaaaaac
    21301 aaatacaaga cagtcattgg agacaatgtc tttgttggtt caaattcaac cattattgca
    21361 ccagtagaac ttggtgacaa ttccctcgtt ggtgctggtt caactattac taaagacgtg
    21421 ccagcagatg ctattgctat tggtcgcggt cgtcagatca ataaagacga atatgcaaca
    21481 cgtcttcctc atcatcctaa gaaccagtag gagcctatca tggagtttga agaaaaaacg
    21541 cttagccgaa aagaaatcta tcaaggacca atatttaaac tggtccaaga tcaggttgaa
    21601 ttaccagaag gcaagggaac tgcccaacgg gatttgattt tccacaatgg ggctgtctgt
    21661 gttttagcag taacggatga acaaaaactg atcttggtca agcagtaccg caaagctatc
    21721 gaggctgtct cttacgaaat tccagccgga aaattggaag taggagaaaa cacagcccct
    21781 gtggcagctg cccttcgtga attagaggaa gaaacagcct atacagggaa attagaactc
    21841 ttgtacgatt tttattcagc tattggcttt tgtaatgaga agttaaaact atatttagca
    21901 agcgatttga caaaagtgga aaatccgcgt ccgcaggatg aggatgaaac cttggaagtc
    21961 cttgaagtga gcttagaaga agcgaaagaa ttaatccaat caggtcatat ttgtgatgcc
    22021 aagacaatta tggctgttca gtattgggag ttgcagaaaa aatagaggag gtcagtatgg
    22081 gtaaatcttt attaacggat gaaatgattg aaagagctaa tagaggcgaa aaaatttcag
    22141 gtcctccttt gctagatgat aatgaggaga ctaagatttt accaacctct tcttcccgtt
    22201 ttggttatgc caatcctaag aatcatggtt ttagccagga aaccttgaag attcaggtcg
    22261 aaccatctat tcataaaagc cgtcgcattg aaaataccaa gagaaatgtc ttcaattcta
    22321 agttgaataa aatcttattc gcggtcatct ttctcttgat tttgcttgtt ttagcaatga
    22381 aacttttgta atagaaaagg aattgaaatg aaaataggaa ttattgctgc tatgccagaa
    22441 gaactggctt atctggtcca gcatttatat aatgtccagg agcaagttgt tttggggaat
    22501 acctatcata caggaaccat tgcttctcat gaagtcgttc ttgtagaaag tggaattggt
    22561 aaggtcatgt ctgctatgag tgtggcgatt ttggctgatc atttccaggt ggatgccctt
    22621 attaatacgg gttcagctgg ggcagtagca gaaggtatcg ctgttgggga tgtcgtgatt
    22681 gctgacaaat tagcctatca tgacgtggat gtcacagctt ttggctatgc ttatggacaa
    22741 atggcgcaac aaccgcttta tttcgaatca gacaaaacct ttgttgctca aatccaagag
    22801 agtttatctc aattggacca aaactggcat cttggtttga ttgctacagg agatagtttt
    22861 gttgcaggaa atgacaagat agaagcgatt aagtcccatt tcccagaagt tttagccgtg
    22921 gagatggagg gggcagctat tgctcaagca gcgcataccc tcaatctccc agtcttagtc
    22981 atccgagcta tgagtgacaa tgccaaccat gaagcaaaca tcttttttga tgagtttatt
    23041 atcgaagctg gacgtcgctc tgcccaagtc ttgttggcct ttttgaaggc tttagattaa
    23101 gcggaaattt gacagttttt ctagcttatg ataagattta agtaaagaaa agctagaaaa
    23161 cgtttcagag gatattatga gtattgaaat gaccgtcagt gagattgcag aggtcttagg
    23221 attatctcgc caagcaatca ataaccgtgt caaagaatta ccagaagaag acacagataa
    23281 aaatgacaaa ggggtaacag ttgttaccag aagtggcttg attaagctag aagaaatcta
    23341 taaaaaaacg atttttgaag atgaacctgt cagtgaagat gtcaaacaac gtgaactgat
    23401 ggagattcta gtggatgaga agaatgcaga aattcttcgt ctttatgaac aattaaaagc
    23461 caaggatcgt cagttatcag aaaaagacga gcagatgcgt atcaaagacc gtcagattgc
    23521 tgagaaagac aaacaattag atcagcaaca acaattgacc cttcaagcca tgaaggatca
    23581 agaaaatctt aagctagagc tggaccaagc aaaagaagaa gtccaatcca ctaaaaaagg
    23641 cttttttgct cgtttatttg gaggataatc aaggagctgt ttaggttaaa tgctaacctg
    23701 atggcttctt ttgtttgtga atagtatagt tgattagaac agagacagta gaggagaggt
    23761 acagaatgga acgattagaa gattacattg cttttgattt agaatttaat cagcacgaag
    23821 gacaaacaca cttgattcaa gtatcggcag tgcgttttag agatggtcgg gaaatcgatg
    23881 cctatgattc ctatgttcat accagcgtcc ctctaaaaag ctttatcaat ggtttgaccg
    23941 ggattacagc tgagacctta aaagatgctc ctccagttga gaaagtctta gaagaattcc
    24001 aagagtttgt gggttctttg ctgatgatag gctacaatgc tgctaaaagt gatttaccta
    24061 ttttagcaga gcatggttta gactatagcc aacagtacaa ggtggatttg tatgatgaag
    24121 cttttgaacg tcggagttca gatttacatg gtattgccaa tctcaaattg caaactgttg
    24181 cctcatttct tggatttcaa ggtcagtctc ataatagttt agaggatgct cggatgacgg
    24241 cgcgtgttta cgaatccttc ttagagtcgg atcaagctag ggaattgtta gagacagaaa
    24301 gtagcttatc aaacaatcct tttggtggct tggacttgtc tcaattattt gactaggagt
    24361 gcctatgaaa cctgaaaaac ctaaaaaatt gggtcttaaa cagatttacc tcaatcttga
    24421 taaaatcctc tttctatttt tcttgatttt tatgatagtg gagtatttgt gggtaccatt
    24481 caattcatgg ttggctagct tcttattaga tcagacaggt tatcttttta tttcctataa
    24541 caatgtctta gccatcctta ctcattctcc attgattagt ctagcttttt tagccttgat
    24601 tgtaattaac tttctggttg cttattttca aataggactc ctctttattg gtgctcgtca
    24661 tctcctctat aatgaaaagc gaaggctaat tgagtatatc cgcaaggttt tccatgaaag
    24721 ttttgaattt atgaaaaagc taactggcgc taaagccttg tttatctttt tctatatagc
    24781 tatgctgttt ccttttatac ggaaaatgct gaagatttat tatcttaata aaatcgtcat
    24841 tccagagttt atccaagctt atttagaaga taaatattgg atgtggtggc tgagcatcct
    24901 acttctatct cttatctttc tctatgtctc tgtcagattg atgtttgccc ttccgaagat
    24961 tgtatatgat cagctgactg ttcgagaagc agtgatgttt agcttggaga aaaccaagaa
    25021 gagagttact ttttatgctt ggaatttatt ttacatcttg ctcaaagcac atttattatt
    25081 ttatcttcct ttgattcctt tattattggc tcaaactttg gtagatgata tcactcagag
    25141 agagtctctg attcttggta ttttgaattt tgtcgtgatt aaaaatctct attatatggc
    25201 tctgacttat tttttggtta aatttgtttc atttttgaca ggaaaggagc tggatatgct
    25261 tcctaggaga gaaaaagatc acatcgtgcg atggggtgtc atgacttgtg ccagtttttt
    25321 ctttgcctta gaaggttata tttatctgga ggctcccatg gttcatctac ctcaacttat
    25381 ttctcaccga ggggtttcca atgcaaatgg gattcaaaat acagtagagt ccttggaaac
    25441 tacagcacaa ctcaaaccag acttggtgga gacggacgtg caggaaacaa aagatgggca
    25501 gtttgtcatg atgcatgatg ctaacttgaa aaatctagca ggtatcaata aaagtcctca
    25561 agacttaaac ttggaggagc ttaaagggat tgatattttt gaaaatggct accagactaa
    25621 aatttcaagc tttgaagatt atctcagtcg agccaacgaa cttggtcaaa aattactaat
    25681 tgaaattaaa accagtaaaa aagatagtcc agacatgatg aaccgctttt tagcccgtta
    25741 tgctgcaaag ctcaagattt atggacatca aatccagtct ttagactacc atgttgtcga
    25801 aaaagtaaga cagtatgatg ccgaactgcc agtttatttc atcatgccct acaattctgt
    25861 ctttcctaaa acaagagcga caggatatac tatggagtac tcaaccttgg atgaatattt
    25921 tgtaagcaaa ctatggacaa cggatcagaa actttatgtc tggactgtca atgattcaga
    25981 agctatcagc aaatctcttc acttaggagt agatggagtg attacagatg atttggaaaa
    26041 agttcagcgg gaaatagaag tagcccaaga agatccagaa tatacggatt tgctcttgaa
    26101 aaaagcattg gaattctttg aattttagta ataaaaaaga ggaacggttg ttcctcccat
    26161 gataggtaag tattcttgtg aatgcttgct tttttgtggt tgcaatccgt ttacgagaat
    26221 tgtttgtatt gttcttgttt caatttactt tatagtgctt tgaagttgga atgctacact
    26281 ataacttct
//
LOCUS       DBEJJV010000029        25651 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.029, whole genome shotgun sequence.
ACCESSION   DBEJJV010000029 DBEJJV010000000
VERSION     DBEJJV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 25651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.029"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            132..629
                     /locus_tag="ACL3GT_001412"
     CDS             132..629
                     /locus_tag="ACL3GT_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HGR0517071.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            629..2284
                     /gene="dnaX"
                     /locus_tag="ACL3GT_001413"
     CDS             629..2284
                     /gene="dnaX"
                     /locus_tag="ACL3GT_001413"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HGR0517072.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2312..2506
                     /locus_tag="ACL3GT_001414"
     CDS             2312..2506
                     /locus_tag="ACL3GT_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HGR0517073.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2656..3426
                     /gene="sufC"
                     /locus_tag="ACL3GT_001415"
     CDS             2656..3426
                     /gene="sufC"
                     /locus_tag="ACL3GT_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HGR0517074.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEGDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3454..4716
                     /gene="sufD"
                     /locus_tag="ACL3GT_001416"
     CDS             3454..4716
                     /gene="sufD"
                     /locus_tag="ACL3GT_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HGR0517075.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4727..5953
                     /locus_tag="ACL3GT_001417"
     CDS             4727..5953
                     /locus_tag="ACL3GT_001417"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HGR0517076.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5940..6380
                     /gene="sufU"
                     /locus_tag="ACL3GT_001418"
     CDS             5940..6380
                     /gene="sufU"
                     /locus_tag="ACL3GT_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HGR0517077.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6434..7846
                     /gene="sufB"
                     /locus_tag="ACL3GT_001419"
     CDS             6434..7846
                     /gene="sufB"
                     /locus_tag="ACL3GT_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HGR0517078.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8045..9286)
                     /gene="pbp3"
                     /locus_tag="ACL3GT_001420"
     CDS             complement(8045..9286)
                     /gene="pbp3"
                     /locus_tag="ACL3GT_001420"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase PBP3"
                     /protein_id="HGR0517079.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9389..10498
                     /gene="cozE"
                     /locus_tag="ACL3GT_001421"
     CDS             9389..10498
                     /gene="cozE"
                     /locus_tag="ACL3GT_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell elongation protein CozE"
                     /protein_id="HGR0517080.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11144..11491
                     /gene="ssrA"
                     /locus_tag="ACL3GT_001422"
     tmRNA           11144..11491
                     /gene="ssrA"
                     /locus_tag="ACL3GT_001422"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11674..11761)
                     /locus_tag="ACL3GT_001423"
     tRNA            complement(11674..11761)
                     /locus_tag="ACL3GT_001423"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11725..11727),aa:Ser,seq:gga)
     gene            11924..12664
                     /locus_tag="ACL3GT_001424"
     CDS             11924..12664
                     /locus_tag="ACL3GT_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0517081.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12661..13572
                     /gene="pfkB"
                     /locus_tag="ACL3GT_001425"
     CDS             12661..13572
                     /gene="pfkB"
                     /locus_tag="ACL3GT_001425"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HGR0517082.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13569..15521
                     /locus_tag="ACL3GT_001426"
     CDS             13569..15521
                     /locus_tag="ACL3GT_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0517083.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHSYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQVP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15658..17910
                     /locus_tag="ACL3GT_001427"
     CDS             15658..17910
                     /locus_tag="ACL3GT_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HGR0517084.1"
                     /translation="MERKEAIQRMLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGS
                     LAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGT
                     MAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWS
                     VYDIAEFFSRGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPP
                     VDMETGEILTEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAK
                     EALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVT
                     KYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFR
                     ELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASI
                     LMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYEL
                     FAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRL
                     GQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLL
                     GRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGE
                     FSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAE
                     GTKPRKVLQQ"
     gene            complement(18061..18489)
                     /locus_tag="ACL3GT_001428"
     CDS             complement(18061..18489)
                     /locus_tag="ACL3GT_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6556 family protein"
                     /protein_id="HGR0517085.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            18627..19769
                     /locus_tag="ACL3GT_001429"
     CDS             18627..19769
                     /locus_tag="ACL3GT_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0517086.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19778..20992
                     /gene="thiI"
                     /locus_tag="ACL3GT_001430"
     CDS             19778..20992
                     /gene="thiI"
                     /locus_tag="ACL3GT_001430"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HGR0517087.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            21127..21951
                     /locus_tag="ACL3GT_001431"
     CDS             21127..21951
                     /locus_tag="ACL3GT_001431"
                     /inference="COORDINATES: protein motif:HMM:NF012958.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="HGR0517088.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            21964..23130
                     /locus_tag="ACL3GT_001432"
     CDS             21964..23130
                     /locus_tag="ACL3GT_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HGR0517089.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            23638..25131
                     /locus_tag="ACL3GT_001433"
     CDS             23638..25131
                     /locus_tag="ACL3GT_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HGR0517090.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25144..>25651
                     /locus_tag="ACL3GT_001434"
     CDS             25144..>25651
                     /locus_tag="ACL3GT_001434"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0517091.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLL"
BASE COUNT         7664 a         4729 c         5615 g         7643 t
ORIGIN      
        1 ctacacaaaa taggctccat aatatccata ggggatttac ccactacaaa tattatagag
       61 cccaaaatcc tttgtttact aaacaaggga tttttctttt gtctctgctc cttttttgat
      121 ataatagttc tatgttaaaa tcagaaaaac aatcacgtta tcaaatgtta aatgaagaat
      181 tgtccttcct attggaaggc gaaaccaatg ttttggctaa tctttccaac gccagtgctc
      241 tcataaaatc acgttttcct aataccgtat ttgcaggctt ttatttgttc gatggaaagg
      301 aattggtttt aggccccttc caaggaggtg tttcctgcat ccgtattgca ctaggcaagg
      361 gtgtttgtgg tgaggcagct cactttcagg aaactgttat tgttggagat gtgacgacct
      421 atctcaacta tatttcttgt gatagtctag ctaaaagtga aattgtggtg ccgatgatga
      481 agaatggtca gttacttgga gttctggatc tggattcttc agagattgag gattacgatg
      541 ctatggatcg agattatttg gaacaatttg tcgctatttt gcttgaaaag acaacatggg
      601 actttacgat gtttgaggaa aaatcttaat gtatcaagca ctttatcgaa aatatagaag
      661 tcaaaacttc tcccagttag ttggtcaaga agttgtggct aagactctta aacaagcggt
      721 ggagcaagag aaaataagtc acgcttatct tttttctggt cctcgtggaa cgggaaaaac
      781 cagtgttgct aaaatctttg ccaaggctat gaactgtccc aatcaagtgg gtggcgaacc
      841 ttgcaataac tgctatattt gtcaagcagt gacggacggt agtttagaag atgtcattga
      901 aatggatgca gcttctaata atggggtaga tgaaattcgc gaaattcgtg ataaatctac
      961 ctatgcgcct agccttgctc gttataaggt ttatatcata gatgaggttc acatgctgtc
     1021 tacaggggct tttaatgccc tcctaaagac gctggaagaa ccaacacaga atgtagtctt
     1081 tattttggcc actactgaat tgcacaagat tcctgctact attctatccc gtgtgcaacg
     1141 ttttgagttt aaatcaatta agacacagga tattaaggaa catattcact atatcttaga
     1201 aaaagaaaat atcagttctg aaccagaggc tgtggaaatc attgccaggc gggcggaagg
     1261 tggaatgcgg gacgccttgt ctattttgga tcaagccctg agtttgacac agggaaatga
     1321 gctgacgact gctatctctg aagaaattac tggcaccatt agcctatcag ccttggatga
     1381 ttatgtggcg gccttgtctc aacaggatgt tcccaaagct ttgtcttgct tgaatcttct
     1441 ttttgacaat ggtaagagca tgactcgttt tgtgaccgat cttttgcact atttaagaga
     1501 cttgttaatt gttcaaacag ggggagaaaa tactcatcat agttcagtct ttgtagaaaa
     1561 tttggcactt cctcaaaaaa atctgtttga aatgattcgc ttagcaacag tgagtttagc
     1621 agatattaag tctagtttgc agcccaagat ttatgctgaa atgatgaccg tccgtttggc
     1681 ggaaatcaag cccgaaccag ctctatcagg agcggttgaa aatgaaattg ctacgctgag
     1741 acaggaagtt gcccgtctca aacaagagct ttctaatgta ggtgcggttc ctaaacaagt
     1801 tgcaccagct cctagtcgac cagctacggg caaaacagtc tatcgtgtcg atcgcaataa
     1861 agtgcaatct atcttacaag aggccgtcga aaatcctgat ttagcacgtc aaaatctaat
     1921 tcgtttgcag aatgcctggg gagaggtaat tgaaagtcta ggtgggccgg acaaggctct
     1981 gctagttggt tctcaaccgg ttgctgccaa tgaacaccat gctattcttg cttttgagtc
     2041 taacttcaat gctggtcaaa ctatgaaacg agacaatctc aataccatgt ttggtaatat
     2101 cctcagtcag gcggcaggtt tttcacctga gattttagct atttccatgg aggaatggaa
     2161 agaagttcgc gcagcctttt cagccaaagc caaatcttct caaactgaaa aagaagtaga
     2221 agaaagcctg attccagaag gatttgaatt tttggctgat aaagtgaagg tagaggaaga
     2281 ctaaagaaag atttcatgat acaataagtt tatgaataaa caacaattta ttattatggc
     2341 gctgtttaca gctgctgaga cctatttttt caatgaagcc tggatgactg gccgctatat
     2401 tatggcagcc ttttgggcaa ttttactctt tagaaatttc cgagtcagtt atgtgatggg
     2461 caaaatcgtt gatgtcatcg atcagcattt taataggaaa gactagccct cagcttccag
     2521 acaaaatcaa agccttttag gctttttttt gttatactag aaaagtatat ttatagaatt
     2581 tttgctctat ttctggggaa atcagacgtt tttctagtaa gtactgtaaa agttttgaaa
     2641 aagaaaggaa ctatcatgtc agtattagag attaaagatc ttcacgttga gattgaagga
     2701 aaagaaattt taaaaggggt taacctgacc ctgaaaacag gagaaattgc cgctatcatg
     2761 ggaccaaatg gtacaggtaa atcgactctt tctgccgcta tcatgggaaa tccaaactat
     2821 gaagtaacta aaggtgaagt tttgtttgat ggcgtaaaca tccttgagtt ggaagtggat
     2881 gagcgtgcgc gtatgggact tttccttgct atgcaatacc catcagaaat ccctggaatt
     2941 accaatgctg agtttcttcg tgccgctatg aatgcgggta aagaaggtga tgagaagatt
     3001 tcagttcgtg agtttattac taagctagat gaaaaaatgg aattgctcaa catgaaagaa
     3061 gaaatggcag agcgttacct caacgaaggc ttctctggtg gtgagaaaaa acgcaatgaa
     3121 attcttcaac ttttgatgtt ggagccaaca tttgctcttt tggacgagat tgactcaggt
     3181 cttgatattg acgctcttaa agttgtgtct aaaggtgtca atgccatgcg tggtgaaggt
     3241 tttggtgcta tgatcatcac tcactaccaa cgtcttttga actatatcac acctgatgtg
     3301 gtacacgtga tgatggaagg tcgtgttgtc ctttctggtg gtccagaatt ggctgcgcgt
     3361 ttggaacgtg aaggatacgc aaaattagct gaagaacttg gctacgacta caaggaagaa
     3421 ttgtaatttc ctcgtatctt ttaggagaag taaatgacta gagaaaatat taaacttttt
     3481 tcagaaatgc acgctgaacc aagctggttg gctgatctcc gtcaaaaagc ttttgacaag
     3541 attgagactt tggaattacc agttattgag cgtgtcaaat tccaccgttg gaatctgggt
     3601 gatggaacga ttacagaaaa tgagccatca gcaaatgttc cagatttcac agctttagat
     3661 catcacttga agttggtgca agtaggaact caaactgttt tcgaacaaac tccagttgag
     3721 ttagctgaac agggtgttgt cttcacagac tttcactcag ctttagaaga aattccagag
     3781 ctgatcgaag aattcttcat gtcatctgtt aagtatgatg atgacaagtt ggcggcttac
     3841 cacacagctt actttaacag tggtgctgta ctctatattc cagataacgt agaaatcaca
     3901 gagccaattg aaggaatttt ctaccaagat agcgatagca atgtgccgtt taacaagcat
     3961 attatgatta tcgctggtaa aaattctaag attagttatc tggagcgttt agagtcacgc
     4021 ggtgaaggaa gtgacaaagc aactgccaat atcacagtgg aagtgattgc acgttctggt
     4081 gcgcaagtca agtttgctgc tattgaccgt ctaggtgaaa acgtcactgc ctacattagc
     4141 cgtcgtggta aattaggcaa cgatgcaagt attgactggg ctatcggtgt catgaacgaa
     4201 ggaaatgtcg ttgctgattt tgatagtgac ttgattggta atggtagcca tgctgacctc
     4261 aaggttgtag ctctttcaag tggtcgtcag gtacaaggga ttgatactcg tgtaactaac
     4321 tatggctgca actctatcgg aaatatccta caacatgggg ttatccttga aaaagcaact
     4381 ttgactttca atggtatcgg ccacatcatc aagggtgcta agggagcaga tgcccaacaa
     4441 gagagccgtg ttctcatgct ttcagaccaa gcgcgttcag atgctaaccc aattcttttg
     4501 attgatgaaa atgacgtcac tgcaggacat gcagcctcta ttggtcaggt agatccagaa
     4561 gatatgtact acctcatgag tcgtggattg gataaggcaa ctgcagagcg tttggttgtt
     4621 cgtggtttcc ttggatctgt tatcgtggag attccagtca aggaagttcg tgatgaaatg
     4681 attgcaacta tcgaagagaa attgtcaaaa cgctaagggg aagcctatgt tagatgtaga
     4741 agcgattcgc aaggattttc caattttaga tcagattgtc aatgatgaac ctctggtcta
     4801 tctggacaat gctgcgacga cacaaaaacc actagtagtt ctgaaagcta ttaacagtta
     4861 ctatgagcag gacaatgcca atgttcaccg tggtgtccat accttagcgg aacgagcgac
     4921 agcttcttat gaagctgctc gtgaaaccat tcgtaagttt attaatgcag gctctacaaa
     4981 ggaagttctc tttaccagag gaacgacaac cagccttaac tgggtggcac gctttgctga
     5041 ggaaattctc actgagggag accaggtctt gatttcagta atggaacacc attctaatat
     5101 cattccatgg caggaagctt gtcgaaagac tggagcagag cttgtctatg tctatcttaa
     5161 agacggtgcc ttggatatgg aggatttgcg agctaaattg actgataagg ttaaatttgt
     5221 ttccctagct catgcctcca atgttcttgg tgtggtcaat ccgatcaagg aaatcactca
     5281 attagcccac caagttgggg caatcatggt agtggatggt gctcaatcta cacctcatat
     5341 gaagattgat gtccaggact tggatctgga ctttttcgcc ttttcgggtc acaagatggc
     5401 tggtccgact ggtatcggtg tcctttacgg caaagaaaag tatcttgagc aaatgtctcc
     5461 agtagaattt ggcggcgaga tgattgattt tgtctacgag caatctgcta gttggaagga
     5521 attgccttgg aaatttgagg ctggaacgcc aaatatggca ggagctattg gacttgcgac
     5581 tgcagttgat tatctggaaa agattggtat ggatgccgtt gaagctcatg aacaggaatt
     5641 gattgcgtac gtctatccaa aactgcaggc aattgaggga ttgaccattt acggttctca
     5701 ggatttggct caacgttcgg gtgttattgc ctttaaccta ggtgatctcc atcctcacga
     5761 tcttgcgaca gctctggatt atgaaggagt ggctgttcgt gctggtcacc attgtgcgca
     5821 acccttgctt cagtatttgg aagtcccagc aacagctcgt gcaagttttt atatctataa
     5881 taccaaggca gattgcgaca aactagtcga tgccctacaa aagacaaagg agtttttcaa
     5941 tggcactttc taaactagat agcctttata tggcagtggt agcagaccat tcgaaaaatc
     6001 cacatcacca agggaagtta gaagacgctg agcaaatcag tctcaacaat ccgacttgtg
     6061 gagatgtcat caatctctct gtcaagtttg atgcagagga ccgtttggaa gatattgctt
     6121 ttctaaattc aggatgcacg atttcaactg cttctgctag tatgatgaca gatgccgttt
     6181 taggaaaaac caaacaagaa attttagaac tggcgactat tttttctgaa atggttcaag
     6241 ggcaaaaaga tgagcgtcaa gaccaacttg gagacgcggc attcttgtca ggtgttgcca
     6301 aattccctca aagaatcaag tgtgcaaccc tagcttggaa tgcccttaag aaaacaattg
     6361 aaaatcaaga aaaacagtaa gacaagtttc ttttgtctta tgaattatta gaaatgaaga
     6421 aagaaaggat attatggctg aagaaagagt agaaccaaaa ccaattgacc ttggtgaata
     6481 taaatttggt ttccatgacg atgtagagcc tgtcttatcg acaggaaaag gactcaacga
     6541 aggtgttatt cgtgaattat ctgctgctaa gggtgagcct gagtggatgt tggagttccg
     6601 tttgaagtct tatgaaacct tcaaaaaaat gcccatgcaa acttggggag cagacttgtc
     6661 agagattgac tttgatgact taatctacta ccaaaaacca tctgacaaac cagcccgttc
     6721 ttgggatgat gtacctgaaa agattaaaga aacctttgaa cgtatcggga ttccagaagc
     6781 tgaacgtgct tatttagcag gggcttctgc ccagtacgag tcagaagtgg tttaccacaa
     6841 catgaaggaa gagttccaaa aattaggtat tatctttaca gatacagatt ccgcactcaa
     6901 ggaataccca gacttattta atcaatactt tgcgaagttg gtaccgccga cagataacaa
     6961 gttggcagcc ctcaactcag cagtatggtc gggtggaact tttatctacg tgccaaaagg
     7021 tgtcaaggta gatattccac ttcaaactta tttccgtatc aataacgaaa atataggtca
     7081 gttcgaacgt accttgatta tcgttgatga gggagcaagc gtccactacg tagaaggatg
     7141 tacagcacca acatattcaa gcaatagctt acacgctgcc attgtagaaa tttttgcttt
     7201 ggacggagct tatatgcgtt atacaactat ccaaaactgg tctgataacg tctataactt
     7261 ggtaacaaag cgtgctaagg ctcaaaagga tgccactgtt gagtggattg atggaaactt
     7321 gggtgccaaa acgactatga aatatccatc tgtttacctt gatggagaag gagcgcgtgg
     7381 taccatgctc tctatcgcct ttgctaatgc agggcaacac caagacacgg gtgctaagat
     7441 gattcacaat gctccacata ccagctcgtc tattgtgtct aaatccatcg ctaaaggtgg
     7501 aggaaaggtt gactaccgtg gacaagtcac ctttaacaag aactctaaga aatctgtttc
     7561 ccacattgaa tgtgatacca ttatcatgga tgacttgtca gcatcagata ctattccatt
     7621 taatgaaatt cacaactcgc aagtggcttt ggaacacgaa gccaaagtat ctaagatttc
     7681 agaagagcaa ttgtattatc tcatgagccg tggattgtca gaatctgagg caactgaaat
     7741 gattgtcatg ggatttgtag aaccctttac aaaagaactt ccaatggaat acgcagttga
     7801 gctgaaccgc ttgattagct atgaaatgga gggatcagtt ggataaaatt tgattttata
     7861 ctcttcgaaa gtctcttcaa accacgtcag catcgcctta ccgtatgtat ggttactgac
     7921 ttcgtcagtt tcatctacaa cctcaaaaca gtgttttgag caacctgcgg ctagcttcct
     7981 agtttgttct ttgattttga agatgaactt gtatcaaaaa atcgcggttt aaaatcgcga
     8041 ttttttataa tttctcgtta acaaagcgga caaactgatt ccaccaaact tttaagaaga
     8101 aggctttttc aattttcttg tctgctacca tttcgaaact agggcgctct gtggtgatgt
     8161 aaccttgacc aatcaagtcc ttgtcttcat aagtcaaatg gccaaccact gttccagctt
     8221 caagtggtgc tgggattgct ttggaatcag gtgtgaattg aacagattgg gaagattgat
     8281 tcccaacacg ttctattaga tagatatcct ctggagccac tgcagttact gtatcttctt
     8341 ttccatcttg tacaggggtt ttgctatctt gataggcatc gccttgttga acgattttgc
     8401 gaagtgtaaa tgtagaagaa atataatcca ttagggaaga tgtagctgta aatcgagcgt
     8461 aaggattatt gtcttgatga tctgcattta aaacaactgt gatgactctc atgccttttt
     8521 cgacagtagt accaacaaaa gactctccag ccttatctgt tgttcctgtt tttagcccat
     8581 caaaaccacc acggtaagca ggcatacctt ctaacatgta gttggttgaa gtgattgtca
     8641 tcccagcaaa agtagaagaa ggttttttgg tgatttctaa gacttgtggg tattttttga
     8701 tgaggttgcg agcaacgata gcgacatcat aagcactaag cttattttcc tcatcttttt
     8761 tagaacctgg gtaaatgtta tcccctagag tttcattgtt aagacctgtc gtattgacaa
     8821 cagtggcatc ctgaattccc cattccaaga gttttgcccg catcatatcg acgaaatctt
     8881 tttctgagcc agcaattttc tcagctaggg caatagcggc gctgttggca ctagatacca
     8941 gagttgcttc aagcaactct tcgacagtat aattacgggc ctccatagga atattactgg
     9001 cttcagaatt tgtcgtcaat tgataaggat aatcagaaat atctacagga gtggagaggg
     9061 taatacttcc gttttccaaa gcttcataga ccagataaac agtaatcaat tttgttatgg
     9121 aagcaatttc gacaggttgc gttgcatcct tctcatagag aattttacca gtatttgcct
     9181 caacagcaat cgcatgttta gcggcaatgg taaaatcttg agcaacagca gtagaagcac
     9241 cccctaaaag agagacagtt aacaaagtta aaaatatttt tttcatagta gtcttattct
     9301 atcataaaga aaaaaaatat tcttgcttta ataattcatc tgttaagctt tttgaaaata
     9361 tggtaaaata aagtgaggga ggtaactcat gtttcgtaga aataaattat ttttttggac
     9421 cacagaaatt ttactcttaa ccatcatctt ttacctatgg agacagatgg gatctttgat
     9481 taaccctttt gttagcgtgc ttaatacaat tatgattcca tttttattag ggggctttct
     9541 ttattatttg acaaacccta ttgttacttt cttaaataaa gtctgtaaac tcaatcgttt
     9601 gcttggtatt ttaattacct tgtgtacttt ggtctgggga atggtcatag gtgttgtcta
     9661 tctcttacct attttgatta atcagttatc tagtttgatt atatctagtc aaactattta
     9721 tagtcgagta caagacttaa tcatagactt atctaattat cctgcgctcc agaatttgga
     9781 tgtagaagct acaattcagc agttaaactt atcctatgtt gatattcttc aaaatatcct
     9841 aaatagcgta tcaaatagtg tggggagcgt cttgtcagct cttatcagta ctgttttgat
     9901 tttgattatg actccagttt ttttggttta tttcttatta gatggacata aattcttgcc
     9961 catgcttgaa agaacgattc taaagaggga tcgcttgcat attgcaggct tattaaagaa
    10021 tttaaatgcg acgattgctc gctatattag tggagtttcg attgacgcaa tcattatagg
    10081 ttgtttggct tatattggct atagtattat tggtttaaaa tatgctttag tttttgccat
    10141 tttttctggt gtagccaatt taattcctta tgtggggcca agtattggtt tgattcctat
    10201 gatcatcgca aatatattca ctgatcccca tagactgctg attgcagtga tttatatgct
    10261 tgttgttcag caggtagatg gcaatatctt atatcctcga attgtaggaa gtgttatgaa
    10321 ggttcatcca atcacgattt tagttttact tttgttgtca agcaatatct atggtgtagt
    10381 tggaatgatt gtcgcagtgc caacctattc tatcttgaaa gaaatttcta agttcttatc
    10441 ccgtttgtat gaaaatcata aaataatgaa agaacgagaa agagaattag ctaagtaaaa
    10501 gtcaggagaa ccctgatttt tctttactgg aagtggcctt tagattagaa gactgaaaat
    10561 aagttaaagt cttaaactaa ttttcacagc taagaatagt agaagttaat ctgataaaaa
    10621 tcgaaaaaac cagtggaatt ccgtgtcagg gtaagttcca ctggttttca tagtctatta
    10681 aagttcgaat gaaacctatt tataatatat tgaaactaga atagtacacc tctaattcta
    10741 aaacattgtt agaaatcgat ttgactgtcc tgatctattc gtactattct tatttcattt
    10801 tactatattt tggtgcaata agtgaaaagt agtccgaata atataaggat tgattttata
    10861 gtttttaaac tcaaatgaat taaaataaag agagtacgaa aattctcatc tgaaagtatt
    10921 ttagaataat tctcttcgtg aatttcttca aaacagatag cttcatctta ggtatgtgtt
    10981 aattggattt cgtaagctct atttacaatc gtaaagttat gcactgagaa agttgtagtt
    11041 agtcttccag tttgctaaat ttctcgaata gtatcttttt taggtatgtg atttcttttt
    11101 gcatttttga gttagataag gtataatggt tttattgtct tttggggtcg ttacggattc
    11161 gacaggcatt atgaggcata ttttgcgact cgtgtggcga cgtaaacgct cagttaaata
    11221 taactgcaaa aaataacact tcttacgctc tagctgccta aaaaccagca ggcgtgaccc
    11281 gatttggatt gctcgtgttc aatgacaggt cttattatta gcgagatacg attaagcctt
    11341 gtctagcggc ttgataagag attgatagac tcgcagtttc tagacttgag ttatgtgtcg
    11401 aggggttgtt aaaataatac ataacctatg gttgtagaca aatatgttgg caggtgtttg
    11461 gacgtgggtt cgactcccac cggctccatt attcctttgc attcttttgc attccttggt
    11521 aaaacgttgt taaatcaacg ttttttattt ttatctttgg tattcctttg cattcttttg
    11581 ctaaaaaggg agtcacaaac agaccctatt ttaaaaaaag gatagaaaaa aggatacaac
    11641 atttgtcgca tcctagaaat aatctttttt cgacggaaga catgggattc gaacccacgc
    11701 acgctattac acgcctaccg cgtttccaac acggcctctt aagcctcttg agtaatcttc
    11761 caatacttac tcaaatagtc taccataaag gctcttatct tgcaataaaa attctagaaa
    11821 taagaaaaaa tgatagattt tgaaagaaaa tgataaaaaa tgcttgactt cgaaagaaag
    11881 tatgatagaa tgaatagtgt aaacgataac aggaggtgat tcagtgttaa aaacagaacg
    11941 taaacaacta attttagagg agttaaatca acatcatgta gtttctctag aaaaattagt
    12001 tagtttgcta gaaacgtcag aatcaacggt tcgaagagac ttggatgagt tggaagcgga
    12061 aaacaagctt cgtcgtgtgc atggtggagc agaactcccc cactccttac aggaagaaga
    12121 aaccattcaa gaaaaatctg tcaaaaacct tcaagaaaag aagttgctgg ctcagaaagc
    12181 agcctctctc attaaagaaa aagatgtcat ctttatcgat gctggaacaa caactgcttt
    12241 tttgattcat gaattggtca ataagaatgt tacagttgtg accaactcca ttcaccatgc
    12301 cgctcagttg gttgaaaagc agattccaac tgtcatggtt ggaggaaacg tcaagacggc
    12361 gacagatgct agtatcgggg gcgttgctct taaccagatt aaccaattgc actttgaccg
    12421 tgcctttatc ggaatgaatg gtgttgacga tggctattat acgactcctg atatggagga
    12481 aggagctgtg aaaagagcta ttttggagaa tgccaagcag acctacgtct tggtggattc
    12541 gtcaaaaatt ggacaaactt gctttgccaa ggtagcacca ctcaaacgcg ctatcgttat
    12601 cactagtcaa gggcatgagc tcttgcaggt tattaaggag aaaacggagg taatagaagt
    12661 atgatttata cagtcacact caatccatcc attgactata tcgttcgttt ggaccaagtc
    12721 aaagttggta gtgtaaatcg tatggacagt gatgataagt ttgctggtgg gaaaggaatc
    12781 aatgtcagcc gtgtcttgaa acgtttgaat ataccaaata cagcgacggg atttatcggt
    12841 ggctttactg gtaaatttat cacagatact ttagcagagg aagaaatcga gacacgtttt
    12901 gtccaggtgg cagaagatac tcgtatcaat gttaaaatca aagcagacca agaaacagaa
    12961 atcaacggaa cgggtccaac tgttgaaccg gttcagctag aagaattgaa agctatttta
    13021 tctagtctga cagcagaaga tacagttgtc tttgcaggtt caagtgctaa aaatctaggc
    13081 aatgttatct ataaggattt gatttccttg acgcgccaga ctggtgcgca agtggtctgt
    13141 gactttgaag gacagacctt aattgatagt ttggactacc agcctcttct tgtaaaacca
    13201 aacaatcatg aacttggagc gatttttggg gttaaactcg aaagtttaga tgaaattgag
    13261 aaatacgctc gtgagttact ggctaagggt gctcaaaatg ttattatctc tatggctggt
    13321 gatggcgccc ttcttgtcac atctgaggga gcttacttcg ctaaaccaat caaaggaaca
    13381 gtcaaaaatt cagttggagc tggtgattct atggttgctg gattcacagg tgaatttgtc
    13441 aaatcaaaag acgcagtaga agccttcaaa tggggagtgg cttgcggaac ggcaactacc
    13501 ttctcagatg acttggcaac ggcggaattt attaaagaaa catatggaaa agttgaggta
    13561 gaaaaaagat gaaaattcaa gacctattga gaaaagatgt catgttgcta gatttgcagg
    13621 caactgaaaa aacagctgtc atcgacgaga tgattaaaaa tttgacagag cacagttatg
    13681 taacagattt tgaaacattt aaagaaggaa ttttggcgcg tgaagctttg acttctactg
    13741 gtttgggtga tggaatcgca atgcctcaca gcaaaaacgc tgctgtcaaa gaagcgacag
    13801 ttctatttgc taagtcaaat aagggtgttg actacgagag cttggatgga caagcaactg
    13861 acctcttctt catgattgca gctccagaag gtgccaatga tactcacttg gcagccttgg
    13921 cagaattgtc tcaatacttg atgaaagacg gttttgcaga caaacttcgt caagcaacat
    13981 ctgcagacca agttatcgaa ctttttgacc aagcttcaga aaaaactgag gaacttgttc
    14041 aagtacctgc taatgactct ggtgacttta tcgtagctgt tacagcttgt acaacaggta
    14101 ttgcccacac ttacatggcc caagaagccc ttcaaaaagt agctgctgaa atgggggttg
    14161 gtatcaaggt cgaaaccaac ggtgctagcg gtgttggaaa tcaactaact gcagaagata
    14221 tccgtaaggc taaagctatt atcattgcag cagacaaggc cgttgaaatg gatcgatttg
    14281 atggaaaacc attgatcaat cgtccagttg ctgacggtat ccgtaagaca gaagagctaa
    14341 ttaacttggc tctttcagga gatactgaag tctaccgtgc cgctaatggt gcaaaagctg
    14401 caacagcctc taacgaaaaa caaagccttg gtggtgcctt ctacaaacac ttgatgagtg
    14461 gtgtatctca aatgttacca ttcgttatcg gtggtggtat catgattgcc cttgccttct
    14521 tgattgacgg tgctttgggt gttccaaatg aaaaccttgg caatcttggt tcttaccatg
    14581 agttagcttc tatgttcatg aaaattggtg gagctgcctt tggtttgatg cttccagtct
    14641 ttgcgggtta tgttgcctac tctattgctg aaaaaccagg tttggtagca ggtttcgtgg
    14701 ctggtgctat tgccaaagaa ggttttgcct ttggtaaaat tccttatgcc gcaggtggtg
    14761 aagcaacttc aactcttgca ggtgtctcat ctggtttcct aggtgccctt gttggtggat
    14821 ttatcgcagg tgccttggtt cttgccatca agaaatacgt taaagttcct cgttcactcg
    14881 aaggtgctaa atcaatcctt ctattgccac ttcttggaac aatcttgaca ggatttgtta
    14941 tgctagctgt gaatatccca atggcagcaa tcaacactgc tatgaatgac ttcctaggcg
    15001 gtcttggagg aggttcagct gtccttcttg gtatcgtcct tggtggaatg atggctgttg
    15061 acatgggtgg accagttaat aaagcagctt atgtctttgg tacaggtacg cttgcagcaa
    15121 ctgtttcttc aggtggttct gtagccatgg cagcagttat ggctggagga atggtgccac
    15181 cacttgcaat ctttgtcgca actcttcttt tcaaagataa atttactaag gaagaacgta
    15241 actctggttt gacaaacatc atcatgggct tgtcatttat cactgaggga gcgattccat
    15301 ttggtgccgc tgacccagct cgtgcgattc caagcttcat ccttggttca gcagtagcag
    15361 gtggactcgt tggtcttact ggtattaaac tcatggcgcc acacggagga atcttcgtta
    15421 tcgcccttac ttcaaatgct ctcctttacc tcgtttctgt cttggtagga gcaatcgtaa
    15481 gtggtgtggt ttatggttac ctacgcaaac cacaagcata aaaaatagaa aaatgaaaag
    15541 attggaccgt ttggtgcagt ctttttctct ttccgaaatg cctgtgaaat atggtataat
    15601 agaagaatgg caaacaagaa tacaagtaca acaagacgga gaccgtctaa agcagaactg
    15661 gaaagaaaag aagcgattca acgaatgttg atttcgttag gaattgcgat tttattgatt
    15721 ttcgcagcct tcaaattagg ggctgcaggt ataacccttt ataatttaat tcgcttgcta
    15781 gtgggtagcc tagcttatct ggcgatattc ggcctattaa tctatctctt ttttttcaag
    15841 tggatacgaa aacaggaagg actcttatct ggctttttca ccatatttgc tggcttactc
    15901 ttgatttttg aagcctactt ggtttggaaa tatggtttgg acaagtccgt tctaaaaggg
    15961 accatggctc aggttgtgac agatctgact ggttttcgaa cgactagttt tgctggaggg
    16021 ggcttgatcg gggtcgctct ttatattcca acagcttttc tcttttcaaa tatcggaact
    16081 tactttattg gttctatctt gattttagtg ggttctctcc tagtcagccc ttggtctgtt
    16141 tacgatattg ctgaattttt cagtagaggc tttgccaaat ggtgggaagg gcacgagcgt
    16201 cgaaaagagg aacgctttgt caaacaagaa gaaaaagctc gccaaaaggc tgagaaagag
    16261 gctagattag aacaagaaga gactgaaaaa gccttactcg atttgcctcc tgttgatatg
    16321 gaaacgggtg aaattctgac agaggaagct gttcaaaatc ttccacctat tccagaagaa
    16381 aagtgggtgg aaccagaaat catcctgcct caagctgaac ttaaattccc tgaacaggaa
    16441 gatgactcag atgacgaaga tgttcaggtc gatttttcag ccaaagaagc ccttgaatac
    16501 aaacttccaa gcttacaact ctttgcacca gataaaccaa aagatcagtc taaagagaag
    16561 aaaattgtca gagaaaatat caaaatctta gaagcaacct ttgctagctt tggtattaag
    16621 gtaacagttg aacgggccga aattgggcca tcagtgacca agtatgaagt caagccggct
    16681 gttggtgtaa gggtcaaccg catttccaat ctatcagatg acctcgctct agccttggct
    16741 gccaaagatg tccggattga agcaccaatc cctgggaaat ccctaatcgg aattgaagtg
    16801 cccaactccg atattgccac tgtatctttc cgagaactat gggaacaatc gcaaacgaaa
    16861 gcagaaaatt tcttggaaat tcctttaggg aaggctgtta atggaaccgc aagagctttt
    16921 gacctttcta aaatgcccca cttgctagtt gcaggttcaa cgggttcagg gaagtcagta
    16981 gcagttaacg gcattattgc tagcattctc atgaaggcga gaccagatca agttaaattt
    17041 atgatggtcg atcccaagat ggttgagtta tctgtttaca atgatattcc ccacctcttg
    17101 attccagtcg tgaccaatcc acgcaaagcc agcaaggctc tgcaaaaggt tgtggatgaa
    17161 atggaaaacc gttatgaact ctttgccaag gtgggagttc ggaatattgc aggttttaat
    17221 gccaaggtag aagagttcaa ttcccagtct gagtacaagc aaattccgct accattcatt
    17281 gtcgtgattg tggatgagtt ggctgacctc atgatggtgg ccagcaagga agtggaagat
    17341 gctatcatcc gtcttgggca gaaggcgcgt gctgcaggta tccacatgat tcttgcaact
    17401 cagcgtccat ctgttgatgt catctctggt ttgattaagg ccaatgttcc atctcgtgta
    17461 gcatttgcgg tttcatcagg aacagactcc cgtacgattt tggatgaaaa tggagcagaa
    17521 aaacttcttg gtcgaggaga catgctcttt aaaccgattg atgaaaatca tccagttcgt
    17581 ctccaaggct cctttatctc ggatgacgat gttgagcgca ttgtgaactt catcaagact
    17641 caggcagatg cagactacga tgagagtttt gatccaggtg aggtttctga aaatgaagga
    17701 gaattttcgg atggagatgc tggtggtgat ccgctttttg aagaagctaa gtctttggtt
    17761 atcgaaacac agaaagccag tgcatccatg attcagcgtc gtttgtcagt tggatttaac
    17821 cgtgcgaccc gtctcatgga agagcttgag atggcaggtg tcattggtcc agctgaaggt
    17881 accaagccaa gaaaagtatt gcagcaataa aaaatagctt ctttccaagg ttggaaggag
    17941 ctattttact ggctattgat tacttttata ctcttcgcaa atctcttcaa accacgtcag
    18001 cttcgccttg ccgtactcaa gtactgtcta cggctagctt cctagtttgc tctttgattt
    18061 tcattgagta ttattttctg aagttggagt attgggctgt ttttcatttt cagtggcagg
    18121 tttacttgta gcaggtgtag tagagtcctg agttgctgtt ttctgatctt cttttttctc
    18181 ttccttgacg ctagattttg gcgtttcttc ttgttgtgtt ttttcttgag aagtgttatt
    18241 ttccttattt ggagtagtat tttcctgagg ggattctttt tgaatttctt tgacaaaggt
    18301 tgtcgtctgg cttgtcgtag gttctttttt agtattttta ttattattat ccaaggcgtt
    18361 catgatcgtg atacccgcgg taatcaaacc aaggatacta ccgatagtag taatggtttt
    18421 ttgaaaaaca gtaaagcctt ttttgatatg ttctgttttc ggttttgaag ttctacgata
    18481 gttagacata cattctctcc tttgattatg atttattata ctctgtttct ttaaaaaaat
    18541 cttaaaaaaa gagaaattgc cctttcttgt cgcaggctcc gtttcatgat acaatagaag
    18601 gagtgatttt agaaagcgtg agaaacatga tttactttga taattcggcg acgaccaggc
    18661 cctatccaga agcccttgaa acctatatgc aggtggcttc aaaaatttta ggaaatccat
    18721 ctagtctcca tcgtttggga gaccaggcaa cacgaatttt agatgcttcc cgtcaacaga
    18781 ttgcagattt aatcggtaag aaaagtgatg aaatcttctt tacatctggt gggacagaag
    18841 gggataactg gatcatcaag ggagtagcat ttgaaaaagc ccagtttggc aagcacatca
    18901 tcgtatcagc cattgaacat ccagcagtta aggaatcagc cctctggttg aaagctcaag
    18961 gttttgaagt ggattttgct ccagttgata acaaaggatt tgtggatgtt gaggcgctag
    19021 aagatttgat aagacctgat acgaccctcg tttccatcat ggctgtgaac aatgaaatcg
    19081 gctctatcca acctattgag gctatttcag aattcttggc agacaagcca actatttcct
    19141 tccacgttga tgcggttcag gcgcttgcca agattccgac tgaaaagtat ctgacagaac
    19201 gagtggattt cgcgactttc tctggtcaca agttccacgg aatccgtggt gttggtttta
    19261 tctatatcaa gtctggcaag aagattacgc ctcttttaac aggtggtggt caggaacgtg
    19321 attaccgttc gacaactgaa aatgtggcag gaattgcagc gaccgctaag gctctccgtt
    19381 tatctatgga aaagctagat atctttagga gcaagactgg gcagatgaag gcagtgattc
    19441 gtcaagcact tctggactat ccggatatat ttgtcttttc agatgaggaa gacttcgccc
    19501 ctcatattct gacttttgga atcaagggtg ttcgtggtga ggtcattgtt cacgcctttg
    19561 aagactatga tattttcatc tcaacgacct cggcttgttc gtccaaggct gggaaaccag
    19621 ccggaaccct gattgctatg ggagtggaca aggataaggc tcagtcagct gtgcgtctta
    19681 gtctagacct tgaaaatgat atgagtcagg tcgagcagtt cttgaccaag ctaaaattaa
    19741 tttacaatca aactagaaaa gtaagatagg agcattcatg cagtattcag aaattatgat
    19801 tcgctacggt gagctgtcaa ccaagggcaa aaatcgtatg cgtttcatca ataaacttcg
    19861 caataatatt tcagacgttt tgtctatcta tccccaagtt aaggtaacag cagatcgcga
    19921 ccgtgcccac gcttacctca atggagcaga ttacacagca gtagcagaat cgctcaaaca
    19981 agtatttgga attcaaaact tttcccctgt ttataaggtt gaaaaatctg tagaagttct
    20041 gaagtctgct gtccaagaga ttatgcagga catctacaag gaaggcatga cctttaaaat
    20101 ctctagcaag cgtagcgacc acacctttga attggacagt cgtgaactca accaaacgct
    20161 tggaggggct gtattcgaag ccattccaaa cgtacaagct caaatgaaaa gtcctgacat
    20221 caatcttcag gtggagatac gtgaagaagc agcctatctt tcttatgaaa ccgttcgagg
    20281 ggcaggtgga ttaccagtgg gaacttctgg taagggcatg ctcatgttgt cagggggaat
    20341 cgattcccct gtagctggct atctagcgct taaacgaggg gtagatatag aggcagttca
    20401 ctttgccagc ccaccttaca cgagtcctgg tgctcttaaa aaagcccaag atttgacccg
    20461 taaattaacc aaatttgggg gaaatatcca gtttatcgaa gttcctttta cagagattca
    20521 agaggaaatc aaagccaaag cgccagaagc ctaccttatg accttgacgc gtcgttttat
    20581 gatgcgtatt actgaccgta ttcgtgaggt acgaaatggt ttagttatca tcaatgggga
    20641 aagtctaggt caagtagcca gccaaaccct tgaaagtatg aaggctatca atgctgttac
    20701 caacactccc atcattcgtc ctgtggttac catggacaag ttggaaatca ttgacatcgc
    20761 ccaggaaatc gatacctttg acatttcaat ccaaccgttt gaagactgtt gtactatttt
    20821 tgcaccagat cgtccaaaaa caaatcctaa aattaagaat gcggagcagt acgaagcgcg
    20881 tatggatgtt gaaggcttgg ttgagcgagc agtggctgga atcatgatta ctgaaatcac
    20941 acctcaagcc gaaaaagatg aagttgatga cttgattgac aatctgctct aattcagaaa
    21001 atccaaaaga atagcgaaaa tcagtaaaaa aagttagttt tttctctaaa aacaggtaaa
    21061 aaactaactt tttttatttt tatgatataa tgatataaaa ttttgaatat agagagtttt
    21121 ctgacaatga atcaatccta cttttatcta aaaatgaaag aacacaaact caaggttcct
    21181 tatacaggta aggagcgccg tgtacgtatt cttcttccta aagattatga gaaagataca
    21241 gaccgttcct atcctgttgt atactttcat gacgggcaaa atgtttttaa tagcaaagag
    21301 tctttcattg gacattcatg gaagattatc ccagctatca aacgaaatcc ggatatcagt
    21361 cgcatgattg tcgttgctat tgacaatgat ggtatggggc ggatgaatga gtatgcggct
    21421 tggaagttcc aagaatctcc tatcccagag cagcagtttg gtggtaaggg tgtggagtat
    21481 gctgagtttg tcatggaggt ggtcaagcct tttatcaagc acaaaacagg ttggtttgat
    21541 ggcatgatga cgacaggttg ctctatggga gcctatcatg cactcaattt cttcctccag
    21601 catccagatg tctttaccaa agtgattgct ctcagtggtg tttacgacgc acgtttcttt
    21661 gtcggcgatt actacaacga tgatgctatt taccaaaact cgccagtaga ttatatttgg
    21721 aaccaaaacg atggctggtt tattgaccgt taccgtcagg cagagattgt gctgtgtacg
    21781 gggcttggag cctgggaaca agatggttta ccatcctttt acaagctcaa agaagccttt
    21841 gaccagaaac aaattccagc ctggtttgct gaatggggac atgatgtcgc ccacgactgg
    21901 gaatggtggc gtaaacaaat gccttatttc ctcggtaatc tctatttata aaaggagtta
    21961 cctatgaatt accttgttat ttctccctac tatccacaaa actttcaaca gtttaccatc
    22021 gaactagcta ataaaggcat cacagtcttg ggaattggtc aagagtctta cgagcaattg
    22081 gatgagccct tgcgcaatag cttgaccgag tattttcgtg ttgataatct tgagaacata
    22141 gatgaagtca aacgtgcagt tgcttttctc ttttataaac atggtccaat tgaccgcatc
    22201 gagtctcaca atgaatactg gcttgagcta gacgcaacac tcagagaaca attcaatgtt
    22261 tttggtgcca aaccagagga tctcaaaaag acgaaatata agtctgaaat gaagaaactt
    22321 ttcaaaaaag caggtgttcc tgtggtacct ggagctgtta tcaagacgga agcagatgtt
    22381 gatcaagcag tgaaagaaat cggtcttcca atgattgcca aacctgataa tggagtggga
    22441 gcagccgcaa cctttaaact tgagacagaa gacgatatca atcacttcaa gcaagaatgg
    22501 gaccattcaa ccctttattt ctttgaaaaa tttgtcactt ccagcgaaat ctgtaccttt
    22561 gacgggctcg tggacaagga tggaaagatt gtcttctcaa caacctttga ctacgcctat
    22621 acaccgcttg acctcatgat ttataagatg gacaattctt attatgtgct caaggatatg
    22681 gatcctaaac tgcgcaagta tggggaagca attgtcaaag aatttggtat gaaagaacgg
    22741 tttttccata ttgagttctt ccgtgagggg gacgattata ttaccatcga gtacaataac
    22801 cgccctgcag gtggttttac cattgatgtt tataactttg ctcattcctt ggacctttat
    22861 cgtggctatg cagctattgt cgcaggagag gagttcccgg cgtcagactt tgaaactcag
    22921 tattgtttgg ctacttctcg ccgtgcaaat gctcactatg tttattcaga agaggatttg
    22981 cttgccaaat atagccagca gttcaaggtt aaaaaagtca tgccagctgc cttcgcggaa
    23041 cttcaaggag attacctgta tatgctgaca actccgagtc gacaagaaat ggatcagatg
    23101 attgctgatt tcggacaacg tcaagaataa gaactatcgg attaaggaaa ttcactccct
    23161 taatcctttt gttttgtctg gtaaaaaata agagcatcct aacaaggtag ctatcataaa
    23221 acttgttcga taactatttg aagcaggatt aggtggctag aaattgaatt ttaacatttc
    23281 aatttagtca tagtattgtg ttttcgtatc cttaaatcag ctaaaaggat ccatgacgac
    23341 acctatacga tatagttttc aggataccaa accagtctat taatactcaa tgaaaatcaa
    23401 agagcaaact aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgtggatag
    23461 aactgacaga gtcagtatca tatacctacg gcaaggtgaa gctgacgtgg tttgaagaga
    23521 ttttcgaaga gtataaaata ttcaggtgac gcatagatat agttaattga agctttgttt
    23581 gaaatctgat aaaataatga tattactaag ttttaaaaac taaagaaaag ggaagatatg
    23641 attacaggcg aattaaaaaa taaaatcgat cagctgtggg aaattctttg gacagaagga
    23701 aacgcaaatc ctttaacaaa tattgaacag ttgacttatc tcttatttat gaaagatttg
    23761 gatagtgtcg agcttggacg tgaaagtgat gctgaatttc tagggattcc ttatgaggga
    23821 gtttttccaa aagataaacc tgaataccgt tggtcaactt ttaaaaatat aggagatgct
    23881 caggaagttt atcgtttaat gactcaggag atttttccgt ttattaaaaa tctcaagggg
    23941 gatacagatg atacagcctt ttcacgatat atgcgagaag ctatttttca aataaataaa
    24001 cctgctacgc ttcaaaaggc aatttctatc ttagatgttt ttccaactag gggattagat
    24061 gtagattttg ataatgacaa acaaagtatt actgatatcg gagatatcta tgaatatctg
    24121 ttatcaaaat tgtcgaccgc aggtaaaaat ggacagttcc gtacacctcg tcacatcatc
    24181 gatatgatgg ttgagttgat gcaaccgact atcaaagata tcatctcaga tcccgctatg
    24241 ggttctgctg gcttcttagt atctgctagc cgttacttaa agcgtaagaa agatgaatgg
    24301 gaaaccaata cagataatat caatcatttt cataatcaga tgtttcatgg aaatgatacg
    24361 gatacgacta tgttgagact tggggcgatg aacatgatgc tacatggagt agaaaatcca
    24421 caaatcagtt accttgactc gctgtctcaa gataatgaag aagccgataa atatactttg
    24481 gttttagcaa atcctccttt taagggctca cttgactaca attcaacctc taatgacctt
    24541 cttgcaaccg taaaaaccaa aaaaacagaa ttactctttc tttctctttt cttgcgaact
    24601 ttaaaaccag gtggacgagc agcagttatc gtacctgatg gtgtcctttt tggttcgtct
    24661 aaagctcata aaggaattcg tcaggaaatt gtagagaatc ataagcttga tgctgtaatc
    24721 tcaatgccta gtggtgtgtt caagccttat gctggagttt caactgccat tctcatcttt
    24781 acaaaaactg gtaatggtgg tactgacaaa gtctggtttt acgatatgaa agcggatggt
    24841 ttaagtttgg atgataagcg acaaccgatt agcgacaatg atattccaga tattatcgaa
    24901 cgctttcatc atcttgaaaa agaagcagaa cgtcagagaa cggatcaatc tttctttgtt
    24961 ccagttgctg agataaagga aaatgattat gatttgtcta tcaataaata taaagagatt
    25021 gagtatgaaa aagttgagta tgaaccaaca gaggtcatct taaagaaaat caatgattta
    25081 gaaaaagaaa ttcaagctgg cttggctgaa ttagaaaaat tactcaagta gggaggtggc
    25141 tgtatgaaaa aagtgaagtt gggggaagtc ttatctctaa aaaaaggcaa gaaagccact
    25201 gtacttgctg aacaaacaac tctaagccaa cgttatattc aaatagatga tttaagaaat
    25261 aataataatt taaaattcac tgaaagttta aatatgactg aagcactccc agatgatatt
    25321 ctgatagcat gggatggagc taatgcagga acagttggtt atggattatc gggagctgtt
    25381 ggtagtacaa ttacggtctt aaaaaagaat gagcgataca aagaaaaaat tatatcagat
    25441 tacttgggag tctttttgga aagtaaatcg cagtatttac gagaacattc aacaggtgca
    25501 acaattcctc atttaaacaa gaatatatta cttgatttac aattagaatt gctaggtatc
    25561 gaagaacaag agaacattat ctgtattctt aatacgatta aagggcttat tactaaaaga
    25621 aaattgcagt tagatgaact aaacttgctc g
//
LOCUS       DBEJJV010000030        22587 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.030, whole genome shotgun sequence.
ACCESSION   DBEJJV010000030 DBEJJV010000000
VERSION     DBEJJV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22587
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.030"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..711
                     /locus_tag="ACL3GT_001435"
     CDS             <1..711
                     /locus_tag="ACL3GT_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517092.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISALYSE
                     LDYNKYWYILHTLIYMLMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIMSFLLFLPIAIFMQICCI
                     RFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVCIWIMG
                     FEFFLLPKLIKLKEQNLV"
     gene            1253..1474
                     /locus_tag="ACL3GT_001436"
     CDS             1253..1474
                     /locus_tag="ACL3GT_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0517093.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            1920..2244
                     /locus_tag="ACL3GT_001437"
                     /pseudo
     CDS             1920..2244
                     /locus_tag="ACL3GT_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            2372..3601
                     /locus_tag="ACL3GT_001438"
     CDS             2372..3601
                     /locus_tag="ACL3GT_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0517094.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFAGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            3621..6317
                     /gene="ppc"
                     /locus_tag="ACL3GT_001439"
     CDS             3621..6317
                     /gene="ppc"
                     /locus_tag="ACL3GT_001439"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008964 - phosphoenolpyruvate carboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA];
                     GO_process: GO:0015977 - carbon fixation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HGR0517095.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAETLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    6400..6617
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            6730..7734
                     /gene="trpX"
                     /locus_tag="ACL3GT_001440"
     CDS             6730..7734
                     /gene="trpX"
                     /locus_tag="ACL3GT_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0517096.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            7803..8669
                     /locus_tag="ACL3GT_001441"
     CDS             7803..8669
                     /locus_tag="ACL3GT_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0517097.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            8666..9424
                     /locus_tag="ACL3GT_001442"
     CDS             8666..9424
                     /locus_tag="ACL3GT_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0517098.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            9514..11274
                     /gene="dnaG"
                     /locus_tag="ACL3GT_001443"
     CDS             9514..11274
                     /gene="dnaG"
                     /locus_tag="ACL3GT_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HGR0517099.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRAGI
                     ESAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFLEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            11277..12386
                     /gene="rpoD"
                     /locus_tag="ACL3GT_001444"
     CDS             11277..12386
                     /gene="rpoD"
                     /locus_tag="ACL3GT_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HGR0517100.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            12400..12729
                     /locus_tag="ACL3GT_001445"
     CDS             12400..12729
                     /locus_tag="ACL3GT_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0517101.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            12844..13887
                     /gene="cpoA"
                     /locus_tag="ACL3GT_001446"
     CDS             12844..13887
                     /gene="cpoA"
                     /locus_tag="ACL3GT_001446"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HGR0517102.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            13903..15228
                     /locus_tag="ACL3GT_001447"
     CDS             13903..15228
                     /locus_tag="ACL3GT_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0517103.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            15259..15435
                     /locus_tag="ACL3GT_001448"
     CDS             15259..15435
                     /locus_tag="ACL3GT_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0517104.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            15494..15628
                     /locus_tag="ACL3GT_001449"
     CDS             15494..15628
                     /locus_tag="ACL3GT_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HGR0517105.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            15692..17002
                     /gene="obgE"
                     /locus_tag="ACL3GT_001450"
     CDS             15692..17002
                     /gene="obgE"
                     /locus_tag="ACL3GT_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HGR0517106.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            17012..17170
                     /locus_tag="ACL3GT_001451"
     CDS             17012..17170
                     /locus_tag="ACL3GT_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517107.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            18257..19516
                     /locus_tag="ACL3GT_001452"
     CDS             18257..19516
                     /locus_tag="ACL3GT_001452"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HGR0517108.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            19532..20083
                     /locus_tag="ACL3GT_001453"
     CDS             19532..20083
                     /locus_tag="ACL3GT_001453"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0517109.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            20076..21353
                     /gene="spxR"
                     /locus_tag="ACL3GT_001454"
     CDS             20076..21353
                     /gene="spxR"
                     /locus_tag="ACL3GT_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS-HotDog domain-containing transcription
                     factor SpxR"
                     /protein_id="HGR0517110.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFWVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            21369..22229
                     /locus_tag="ACL3GT_001455"
     CDS             21369..22229
                     /locus_tag="ACL3GT_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HGR0517111.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            22454..>22587
                     /locus_tag="ACL3GT_001456"
     CDS             22454..>22587
                     /locus_tag="ACL3GT_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGR0517112.1"
                     /translation="MSQSIVPVEIPQYCRFDSKKRNGILFNVRIANLKFTFFRLDFLR
                     "
BASE COUNT         6949 a         3832 c         4967 g         6839 t
ORIGIN      
        1 atgaagttac ttaaaaatga attgattaag agtaaaatat ttttatttat tattgttgac
       61 atctgtattc agattctagt cattctagct ataaaaacat atattttaga tatttcggca
      121 ctatactcag agcttgatta taataagtat tggtatattt tacacacttt aatatatatg
      181 ctaatgattt ttcctataca aattttgtat caaaatctaa gagaggcatt gattgaagat
      241 aataataatg gttggaatat catggtgatt aacactaata atctcgtgaa aatcatctat
      301 ataaaagtaa cgataaatat cgtgagatgt tttatttgtt attttgttta tacaattttt
      361 tctttaattc aattaggtgg tatgggaact gatatgttat taaccaatat aatatttccc
      421 aatataatgt catttctttt atttttacct atagctatct ttatgcaaat ttgctgtata
      481 agatttgatt ccattttagc aaaggcctta cctaatattt tgctgatact tattgtttta
      541 atcacgtttc agagtgattg gaatatattt atacctgcaa cttattatta tacagaaatt
      601 cagtcaacta caaacttagg tattaaatta ttagtttgta tctggattat gggatttgaa
      661 tttttccttc ttccaaaact aataaaattg aaagaacaaa atctagttta aatgttgctc
      721 gaaaattaaa taattgaata cgattaacaa tgaaacaata caacgtgagt catgacttca
      781 aagtaattga ttttatgatt ctggtttctt acgcttaatt aagcaagttg tattcacttt
      841 atcaaattgt tattactcta aaaagcgtct aacagctata gagtgtctgt ttgcttctct
      901 ttacttttat tttaaataat tcattaacct tccgtaagtg cccaataata aggtgtgttg
      961 aagaagtctg agataaaata gttctcagtc acaaaaaagc tatagattcc cattggtgaa
     1021 cagctccctg tcaagtagac agtaaaataa tataaaatct taagcgacct gattcctgaa
     1081 ttccagtgga gtcaggttgt tttttaaccg tctttcttaa tattgtctta cctataatag
     1141 atatgcttat gagatatgtt taataaatta attttagttc aaaatgtcca gttaggacac
     1201 tttgaatgat ttcttagttt tatatattat acttttctca ggagaaagct agatgtacag
     1261 acgtttgaga gatttgaggg aagatcacga tttgacccaa aaacaaatag ctaaaatact
     1321 ttcgtttaca aactcagctt atgctaaaat tgaacggggt gagcatacgt taacagcaga
     1381 tgtattggta actctctcaa acttttacga tgtcagtaca gactacctat tggaattgac
     1441 agattttcct gataaaattc gctttagaaa ataatctcct caatttcata gagtgtgaaa
     1501 atgaggagat tttttatttg ttctttgaaa attaaatagt ccaaaatggt actttcctca
     1561 tttgtggagc aaatttgaat ggctcgccat gataagagcg attttaaaac catcaataaa
     1621 atagagcgat actttatatg ccatgataca aatgatatac aatgatactt ctgaccgttc
     1681 aggctgccat cgtaaaagag cagcaagtga aattcttatg atgacttcat cagtcatgcc
     1741 acgttaaatg tgtgagtttg ttagagaaac gcaattaatc ctcaaaaggt tccccgaacc
     1801 ttttgagttc cacagacgca tcacgtggag tgtgtaagct tgttgctaaa agcgtaaaaa
     1861 ccttggaacg aaaggaataa tagacttcct gcgaaacaaa aatacaatac aataaaacta
     1921 tggatgatga agcaagtaaa caattaagcg atagccgttt caagagcctt gtaggtgttc
     1981 agcgcacgag atgttagctg tgttaaaaac agcttatcaa cgcaacgtaa acgcgcaaaa
     2041 ggtggacgaa aaaccaaatt aagcctagac gatctcctca tggtaactat tcaatacatg
     2101 cgagaatagc gcacttatga acaaattgcg gctgattttg gcattcacga aagcaactta
     2161 atccgtcgga gccaatgggt tgaagtaact cttgttcaaa atggttttac gatttcaaat
     2221 tctgccctaa ttatgaaaaa cagtaaaatt cgaaggattg taaggtaaga gtttttttct
     2281 ttctgaaaaa atggtataat agcaatcaaa actagaaaat aaaacggaat ttggaacaga
     2341 tttgtctgta tcctagtaga gtggtgatgc tatgaagatt agtaagaggc acttattaaa
     2401 ttattccatc ttgattccct acttgctttt atctattttg ggcttgattg tggtctattc
     2461 gaccaccagt gctattttaa ttgaagaagg caagagcgcc ttgcagttgg ttcgaaacca
     2521 aggaatcttt tggattgtta gtttgatact gattgcctta atttataaat tgagactaga
     2581 ttttttgaga aatgagcgac taatcatttt agttatatta atagaaatgc ttttattgtt
     2641 cttggctcgt tttattggta tttccgtaaa cggggcatac ggttggattt cggttgcagg
     2701 agtaactatt cagccagctg agtacttaaa aatcattatt atttggtatt tagctcaccg
     2761 attctccaaa cagcaagaag aaatagctac ttatgatttt caagttttga ctcaaaatca
     2821 atggcttccc cgtgctttta atgattggcg attcgttctc ctagttctga ttggaagttt
     2881 gggaattttc cctgatttag gaaatgcgac tattttagtc ttggtttcct tgattatgta
     2941 tacagttagt ggaatcgctt atcgctggtt ttcaaccatt ctggcgctcg tatctgccgc
     3001 ttctgtcttt gtcttgacca ctatcagcct aatcggtgtt gagacctttt caaaaattcc
     3061 agtatttggc tatgtagcca agcgctttag tgcctttttt aatccttttg ccgatcgtgc
     3121 tgatgcaggt caccagttag ctaattctta ttttgccatg gtcaatggtg gttggtttgg
     3181 tctaggtctt ggaaactcga ttgaaaaacg aggttatttg ccagaagctc atacagactt
     3241 tgtcttttct atcgtgattg aagaatttgg ctttgctggt gccagtctta ttttagctct
     3301 cttgtttttc atgattttgc ggattatctt ggtcggtatt cgagcggaga atcctttcaa
     3361 tgccatggtt gcactcggtg tcggagggat gatgttggtt caggtatttg tcaatatcgg
     3421 agggatttcg ggcttgattc catctacagg agtaaccttc cccttcttat cccagggtgg
     3481 aaatagtctt ctagtcttat cagtggcagt agcctttgtc ttaaatattg atgccagtga
     3541 aaaacgcgct aagttgtacc gagaattgga aaatcaacca atgaaccttc tgttgaagta
     3601 ggataaagaa aggatagttt atgtctcttc aaaaattaga aaattatagt aataaaagtg
     3661 ttgtgcaaga agaagtcttg attctaacag aattactgga agatattact aaaaatatgc
     3721 ttgccccaga gacctttgaa aaaataatac agttgaaaga attatcaacg caggaagatt
     3781 atcaaggtct aaaccgtcta gtgactagct tatcaaatga tgaaatggtc tatatttcac
     3841 gctatttctc tatcttacct cttttgatca atatttcaga ggatgtggat ttagcttatg
     3901 aaatcaatca tcaaaataat attgatcagg actatttagg taaattatct acaacgatta
     3961 aattggtagc agaaaaggaa aatgccgttg agatcctaga acacttgaat gttgtccctg
     4021 ttttgacagc ccatccaaca caagtgcaac gcaaaagtat gttggattta acaaatcata
     4081 ttcatagtct tttgcgtaaa taccgtgatg ttaagttggg gttgatcaat aaagataaat
     4141 ggtacaatga tttgcgtcgt tacatcgaaa ttatcatgca gacagacatg attcgtgaga
     4201 aaaaattaaa agtgactaac gaaatcacga atgctatgga atattataac agctcctttt
     4261 tgaaagctgt acctcatttg acgacggagt ataagcgctt agcgcaagcg catggtctga
     4321 atttaaaaca ggctaaacca atcaccatgg gtatgtggat aggtggtgac cgtgatggaa
     4381 atccatttgt tacagcagag accttgaagc agtctgcact cactcaatgt gaagtcatca
     4441 tgaactacta tgataaaaag atttaccaac tttatcgtga attttctctt tcaactagca
     4501 ttgtcaacgt cagcaagcaa gtcagagaaa tggctcgtca atccaaggat aactcgattt
     4561 accgcgaaaa agagctttac cgtcgtgcct tgtttgatat tcaatcaaaa attcaggcaa
     4621 ctaaaaccta tctgattgag gatgaagaag ttgggactcg ttatgaaacc gccaatgatt
     4681 tctacaagga tttgattgcc attcgagatt ctctactaga aaataagggt gagtccttga
     4741 tttcaggtga ttttgtggaa ttattgcagg cagtagagat atttggtttt tacctagcat
     4801 caattgatat gcgacaagac tctagcgtct atgaagcctg tgtggcagaa ctcttgaaat
     4861 cagcaggaat tcattctcgt tatagcgagt tgagcgaaga agaaaagtgt gaccttctct
     4921 tgaaagaatt agaagaagat ccccgaattc tttctgcgac tcacgcagaa aaatcagaat
     4981 tattagcaaa agaattagct atttttaaga cggctcgtgt tttgaaagat aagttgggag
     5041 atgatgtcat ccgtcagacc atcatttcac atgcaaccag cctttctgat atgctagaat
     5101 tagctattct gttaaaagaa gtaggactgg tggatacgga aagggcgcgt gttcagattg
     5161 ttcccctttt tgaaacaatt gaagacttgg atcattcaga agaaacaatg agaaaatatc
     5221 tttctcttag ccttgccaaa aaatggattg actcacgaaa taactaccaa gaaatcatgc
     5281 ttggctactc tgacagtaat aaagatggcg gttacttgtc atcatgttgg accctctaca
     5341 aggctcaaca acaattgact gctattggag atgaatttgg cgttaaggtt accttcttcc
     5401 atggtcgtgg tggtactgtc ggtcgtggtg gtgggccaac ctatgaagcc attacatctc
     5461 aaccgctcaa gtctatcaag gatcgtatcc gcttgacgga gcagggtgaa gtaattggga
     5521 ataaatacgg taacaaagac gccgcttact ataaccttga aatgctagta tcggcagcta
     5581 ttaaccgtat gattactcag aagaagagcg ataccaatac cccaaatcgt tatgaagcca
     5641 ttatggatca agtagtggac cgtagttacg atatctaccg tgatttggtc tttggtaatg
     5701 agcatttcta tgattatttc ttcgagtcaa gtccaatcaa ggctatttca agttttaata
     5761 ttggttctcg tccagccgct cgtaagacta ttactgaaat cggtggtttg cgtgccatcc
     5821 cttgggtatt ctcatggtca cagagtcgtg ttatgttccc tggatggtac ggggttggtt
     5881 caagcttcaa ggaatttatc aataaaaatc cagagaatat tgctatctta cgagatatgt
     5941 accaaaattg gcctttcttc caatcgcttc tttcaaatgt tgatatggtt ttgtcaaaat
     6001 caaatatgaa tattgctttt gaatatgcta aactttgtga agacgagcaa gttaaggcca
     6061 tctatgagac tattttaaat gaatggcaag ttactaagaa cgttatcttg gctattgaag
     6121 gacatgacga actcttagct gacaatccat atctaaaagc tagtctggat taccgtatgc
     6181 cttactttaa tattctcaac tatattcagt tagagttgat taaacgccaa cgtcgtggag
     6241 aattgtccag tgatcaagaa cgattgattc atatcaccat caacggaatt gcgacaggat
     6301 tgcgtaattc aggttgataa ttttcaagag tgaatgctaa aagtgaatat caaaaaaatt
     6361 ctaatagact attgacaagt agtttaaaaa tgatataatt taaccattca gaaaagtaat
     6421 catacaaact ttttagagag tctgtggtag ctgaaaacag ataagtggcg atgatgaaaa
     6481 ttgggctgaa tgctatttag aatttgaaat tataaaaatt cggtaagcac accttacagt
     6541 gcatctcgtt attgcgagac tgagcgatag ggaaattccc tataattgag gtggtaccgc
     6601 gcatcgacgt cctcacacaa gttttttgtg tgaggatttt tttgatggag gttagtatgg
     6661 aaagaaaacg atggcgtcgc ttgtttagat aagtgaaata tgttaaagga aataaaaagg
     6721 agaaacagaa tgaaaaataa acgtttaatt ggaattattg ctgcattagc agtcttagta
     6781 gcaggaagct tgatttattc ttcaatgaat aaatcagaag ctcagaataa taaggatgag
     6841 aagaaaataa ctaagattgg tgtgcttcaa tttgtgagcc atccatccct tgatttgatt
     6901 tataaaggga tccaagatgg acttgcagaa gaaggatata aagatgatca agttaaaatt
     6961 gattttatga actcagaagg tgaccaaagt aaggttgcga caatgagtaa acaattggtt
     7021 gcaaatggga atgaccttgt ggttggtatc gcaacaccag cagcccaagg gttggctagt
     7081 gcaacaaaag acctaccggt tatcatggcc gctattacag acccaattgg tgctaacttg
     7141 gttaaagatt tgaaaaaacc aggtggcaac attacagggg tatctgacca caatccagct
     7201 caacaacaag ttgaactcat caaggctctg acaccgaatg tgaaaacaat cggagctctt
     7261 tactcaagta gcgaagacaa ttcaaaaaca caggtcgaag aatttaaggc ttatgctgaa
     7321 aaagcaggtc tgacagtgga aacatttgca gttccttcaa caaatgaaat tgcctcaact
     7381 gtcactgtta tgactagcaa ggtagatgct atttgggttc caattgataa caccattgca
     7441 tcaggatttc caacggttgt ctctagcaat caaagttcta agaaaccaat ttatcccagt
     7501 gcgacagcta tggtagaagt aggtggtttg gcatcagttg taattgacca acatgacctt
     7561 ggtgtggcaa caggtaaaat gattgtgcaa gtcttgaaag gtgcaaaacc agccgatacc
     7621 ccagtcaatg tcttttcaac tggtaagtca gtcatcaata aaaaaatagc acaagaacta
     7681 ggtattacta ttcctgagtc tgttctcaaa gaagcaggac aagtcatcga ataaataagg
     7741 tagggaggag gagactcttc ccatttttta aaaagatgaa tatagaaagg attaaataaa
     7801 atatgattgt ttccattatt tctcaaggat ttgtctgggc tattctaggt ctgggaatct
     7861 ttatgacatt taggatttta aactttccag atatgacgac agaaggttcc ttccctcttg
     7921 ggggagctgt tgctgtcact ttgataacca aaggcgtgaa cccattttta gcgacacttg
     7981 ttgctgtagg agcaggttgt ttggctggaa tggcagcagg ccttctttat acaaaaggga
     8041 agatcccaac cttgctatca gggattttgg tgatgacttc ttgtcactca atcatgctct
     8101 tgattatggg acgtgcgaat ttaggcctgc ttggaaccaa gcaaattcag gatgttttgc
     8161 cttttgattc ggatttgaat caactcttga caggtctcat ctttgtgagt attgttattg
     8221 ctctcatgct ctttttcttg gacactaaac tcggacaagc ctatattgct acaggggata
     8281 atcctgatat ggctagaagt ttcgggattc atactggacg catggagctc atgggcttgg
     8341 tcttatcaaa tggtgtgatt gcccttgcag gtgccctcat tgctcagcaa gaaggttatg
     8401 ccgatgtgtc tcgagggatc ggggttatcg ttgtggggct tgcaagtttg attattggag
     8461 aagttatttt caagagtttg agcttggcag agcgtttggt tactatcgtt gtaggttcta
     8521 tcgcttatca atttttagtg tgggcagtta tcgcacttgg ctttaataca agttaccttc
     8581 gtttatacag tgccttgatt ttagcagtct gcctcatgat tccaacattt aagcaaacaa
     8641 tcttgaaagg agccaagtta agcaaatgac agcaattgta gaattaaaaa atgcaaccaa
     8701 aatcgttaaa aatggctttg atgaagaaaa gattatttta aatgatgttt ccttagaaat
     8761 ttttgaacgg gactttatca cgattttggg cggaaatggt gctggaaaat caaccctctt
     8821 taacactata gcagggacct tatcactaac tagtggaact atccgtattt taggtgaaga
     8881 actcactaag ttttcacccg agaagcgtgc caagtacctg tctcgtgtct tccaagatcc
     8941 aaagatgggg acagctcccc gtatgacggt cgctgaaaat cttttaatcg ccaagtttcg
     9001 tggtgaaaag cgtggattgt taccacgacg cttgactagc tataaggatg aatttcaggc
     9061 aaccattgaa aaagtaggaa atggtcttga gaaacacttg aatacaccga ttgagttctt
     9121 atcaggtgga caaagacagg ctttgagtct cttgatggca accttgaagc gacctgaatt
     9181 actcctgtta gatgagcata ctgctgccct ggatccaaag actagtgttg ctttgatgga
     9241 attgacagat gaatttgtta agaaagatca gctaacagcc cttatgatta ctcatcatat
     9301 ggaagatgct ctcaaatacg gcaatcgctt gattgtcatg aaagaaggac ggattatcca
     9361 agatttaaac caagaagaaa aagcaaaaat gaaaatctct gattattatc aactctttga
     9421 ataaagtagg gaaaatgagt gaaatggttt actttttttc tgaaataaag tatactatat
     9481 aaagtaaact atgataacat ggaggtattg tgtatggttg acaaacaagt cattgaagaa
     9541 atcaaaaaca atgccaacat tgtggaagtc ataggagatg tgatttcttt acaaaaggca
     9601 ggacggaact atctagggct ctgtcctttt catggtgaaa aaacaccttc tttcaacgtt
     9661 gtagaggata agcagtttta tcactgtttc ggttgtggtc gctcaggtga tgtctttaag
     9721 ttcatcgagg agtaccaagg ggttcccttt atagaggcag tccaaatctt aggtcagcgt
     9781 gttggaattg aggttgaaaa accgctttat agtgagcaga agccagcctc acctcaccaa
     9841 gctctttatg atatgcacga agatgcagcc aaattttacc atgcgattct catgacaacg
     9901 actatgggcg aagaggccag aaattacctt tatcagcggg gtttgacaga tgaagtgctt
     9961 aaacattttt ggattggttt agcacctcca gaacgaaact atctctatca acgtttgtct
    10021 gatcagtatc gtgaagagga tttactggat tcaggcctgt tttatctctc ggatgccaat
    10081 caatttgtag acacctttca caatcgcatt atgtttcccc tgacaaatga ccaaggaaag
    10141 gtcattgcct tctcaggtcg tatctggcaa aaaacggatt cacaaacttc taagtataaa
    10201 aacagccgat cgactgcaat ttttaacaaa agttacgaat tatatcatat ggatagggca
    10261 aaaaaatctt ctggaaaagc tagtgagatt tacttgatgg aaggattcat ggatgttatt
    10321 gcagcctatc gggctggaat cgaaagtgct gtggcgtcga tgggaacggc cttgagtcga
    10381 gagcatgttg agcatctgaa aaggttaacc aagaaattgg ttcttgttta cgatggagat
    10441 aaggctgggc aagccgcgac attgaaagca ttggatgaaa ttggtgatat gcctgtgcaa
    10501 atcgtcagca tgcctgataa cttggatcct gatgagtatc tacaaaaaaa tggtccagaa
    10561 gacttggcct atctattaac gaaaactcgt attagtccga ttgagttcta cattcatcag
    10621 tacaaacctg aaaacagtga aaatctgcag gctcagattg agtttcttga aaaaatagct
    10681 cccttgattg ttcaagaaaa gtccatcgct gctcaaaaca gctatattca tattttagct
    10741 gacagtctgg cgtcctttga ttatacccag attgagcaga ttgttaatga gagtcgtcag
    10801 gtgcaaaggc agaatcgcat ggaaggaatt tccagaccga cgccaatcac catgccaatc
    10861 accaagcagt tatcggctat tatgagggca gaagcccatc tactctatcg gatgatggaa
    10921 tcccctcttg ttttgaacga ttaccgtttg cgagaagact ttgcatttgc tacacctgaa
    10981 tttcaggtct tatatgactt gcttggccag tatggaaatc ttcctccaga agttttagca
    11041 gagcagacag aggaagttga aagagcttgg taccaagttt tagctcagga tttgcctgct
    11101 gaaatatcgc cgcaggaact tagtgaagta gagatgactc gaaacaaggc tctcttgaat
    11161 caggacaata tgagaatcaa aaagaaggtg caggaagcta gccatgtagg agatacagat
    11221 acagccctag aagaattgga acgtttaatt tcccaaaaga gaagaatgga gtaataatgg
    11281 caacaaaaca aaaagaagta acaacatttg acgtacaggt agcagaattt atccgtaatc
    11341 ataagcaaaa agggacagca acagatgatg aaatcaatgc aagtctggtt attcctttta
    11401 ccttggacgc tgatgggatt gaagatctct tgcaacggat tcaggatgca ggaatttcta
    11461 tcacagataa cgaaggaaat ccaagtgcgc gtgttcttag caatgaagaa gaaccagaac
    11521 tcagcgatga ggacttgatt gggtcaactt ctgctaaggt caatgaccct gtccgtatgt
    11581 acttgaaaga aataggggtc gttcctctct tgaccaatga agaggagaaa gagttggcac
    11641 tggctgttga agctggtgat atcgaagcca aacaacgtct tgcggaagcc aatcttcgtt
    11701 tggttgtttc cattgccaaa cgctatgtcg gtcgtggcat gcagttcctt gacttgattc
    11761 aagaaggaaa tatgggcttg atgaaggcgg ttgacaagtt tgactattct aaagggttca
    11821 agttttcaac ttatgcaact tggtggattc gtcaggctat cactcgtgct attgcggacc
    11881 aagctcgtac catccgtatc ccagttcaca tggttgaaac tatcaataaa ttggttcgtg
    11941 aacagcggaa tctccttcaa gaattggggc aagatccgac accagaacag attgctgaac
    12001 gaatggatat gacacctgat aaggttcgtg aaatcttgaa gattgcccaa gaaccagtat
    12061 ctcttgaaac tcctatcggt gaagaggacg atagccacct tggagacttt atcgaagatg
    12121 aagtgattga aaatccagtg gattatacga ctcgtatcgt cttgcgtgag caattggatg
    12181 aaatcttaga tactcttaca gaccgtgaag aaaatgttct gcgtctacgt tttggactag
    12241 atgatggaaa aatgcgcaca cttgaagatg tggggaaagt ctttaacgta actcgtgagc
    12301 gtatccgtca gattgaagca aaggctttga gaaaactacg ccaaccaagt cgtagcaaac
    12361 cgcttcgtga ttttattgaa gactaagagt gaggaaaata tggcttatac agaagagcaa
    12421 attgaaaaca tcaaaacacg gattttaaca gccttggaag aagtcatcga ccctgagttg
    12481 ggaatcgata ttgtcaatct tggtttgatc tatgagattc gttttgacgg tgacacaggg
    12541 caaacagaga ttgacatgac tttgacaact atgggttgtc ccttagcaga ccttttgaca
    12601 gaccagattt atgatgctat gatagaggtt ccagaagtaa cggatactga ggttaaatta
    12661 gtctggtatc cagcctggac agttgaaaaa atgagtcgct atgcccgcat tgccctaggc
    12721 attaagtaaa catataaaag catgtgagag actgttggaa aagcgaggaa atttcccctc
    12781 ttttcctcta gtctctcctt tcttttgctg attttattca aagaaaatga tataatagta
    12841 gttatggaga aaaagaaatt acgcatcaat atgttgagtt caagtgagaa agtagcagga
    12901 cagggagttt caggtgctta ccgtgaatta gttcgtcttc ttcaccgtgc tgccaaggac
    12961 caattgattg ttacagaaaa tcttccaatc gaggcagatg tgactcactt tcatacgatt
    13021 gattttccct attatttatc aaccttccaa aagaaacgct cagggagaaa gattggctat
    13081 gtgcatttct tgccagctac acttgaggga agtttgaaaa ttccattttt cttaaaggga
    13141 attgtgaaac gctatgtatt ttctttttac aaccggatgg agcacttggt tgtggtcaat
    13201 cctatgttta ttgaggattt ggtagcagct ggtattccac gtgaaaaagt gacctatatt
    13261 cctaactttg tcaacaagga aaaatggcat cctctaccac aagaagaggt agtcagactg
    13321 cgcacagatc ttggtcttag tgacaatcag tttatcgtag taggtgctgg gcaagttcag
    13381 aaacgtaaag ggattgatga ctttatccgt ctggctgagg aattgcctca gattaccttt
    13441 atctgggctg gtggcttctc ttttggtggt atgacagatg gttatgaaca ctataagaaa
    13501 attatggaaa atccccctaa aaatttgatt tttccaggca ttgtatcgcc agagcggatg
    13561 cgcgaattgt atgctctagc ggatcttttc ttgttgccta gttacaatga gctctttcct
    13621 atgactattt tagaagctgc gagttgtgag gctcctatta tgttgcgtga tttagatctc
    13681 tataaggtaa ttttggaggg aaattatcgg gcgacagcgg gtagagaaga gatgaaagag
    13741 gctattttgg aatatcaagc aaatcctgct gccttaaaag atctcaaaga aaaggctaag
    13801 aatatttcca gagagtattc tgaagagcat ctgttacaaa tctggttgga cttttatgag
    13861 aaacaagccg ctttagggag aaagtaaaaa gtgaggtaat ctatgcgaat tggtttattt
    13921 acagatacct attttcctca ggtttctggt gttgcgacca gtattcgaac cttgaaaaca
    13981 gaacttgaaa agcagggaca tgctgttttt atctttacga cgacagataa ggatgtcaat
    14041 cgctacgaag attggcaaat tatccgcatt ccaagtgttc ctttctttgc ttttaaggat
    14101 cgtcgctttg cctaccgagg ttttagcaag gcacttgaaa ttgctaaaca gtatcagcta
    14161 gatattatcc atactcagac agaattttct cttggcctgt tggggatttg gattgcgcgt
    14221 gaattgaaaa ttccagtcat ccatacctat cacacccagt atgaagacta tgtccattat
    14281 attgctaagg ggatgttgat ccggccgagt atggtcaagt atctggttag aggtttcctg
    14341 catgatgtgg atggggttat ttgtcctagt gagattgtcc gtgacttgct atctgattat
    14401 aaggtcaagg ttgaaaaacg ggtcattcct actgggattg aattagccaa gtttgagcgt
    14461 ccggaaatca agcaggaaaa tttgaaagaa ctgcgtagta aactagggat tcaagatggt
    14521 gaaaagacgt tgcttagtct ttcgagaatc tcctatgaaa aaaatattca agcagtttta
    14581 gcagcctttg ctgatgttct gaaagaggaa gacaaggtta aactggtagt agctggggat
    14641 ggcccttatc tgaatgacct caaagagcaa gctcagaacc tagagattca agactcagtc
    14701 atctttacag ggatgattgc tcctagtgag acggctcttt actataaagc ggcggatttc
    14761 ttcatttcgg catcgacaag cgaaacgcaa ggtttgacct acttggaaag cttagccagt
    14821 ggaacacctg tcattgctca cggaaatcct tatttgaaca acctcatcag tgataaaatg
    14881 tttggaacct tgtactatgg agaacatgat ttggctggtg ctattttgga agccctgatt
    14941 gcaacaccag acatgaacga gcatacctta tcagagaaat tgtatgagat ttcagctgag
    15001 aactttggga aacgagtgca tgagttttat ctggatgcca ttatttcaaa taacttccag
    15061 aaagatttgg ctaaagatga tacggtcagt cagcgtatct ttaagacagt tttgtatctt
    15121 cagcaacagg tggttgctgt acctgtaaaa ggatctagac gcatgttgaa ggcttcaaaa
    15181 acacagttga tcagtatgag agactattgg aaagaccatg aagaatagaa agaggaacag
    15241 ctatgaaaaa aacaattaat gagaagcggt cgtgataaaa agattgcggg tgtttgtgct
    15301 ggggtggccc attatctgga tatggatccg actatcgttc aagtcatttg gggtgttctt
    15361 acttgctgtt acggagctgg aattgtagct tacattattt tatggattat cgcaccagta
    15421 gcaactgact attgaaaact agctcaattc atgctaagat aatagaaaat agaatgtaac
    15481 gaaggagaga aaaatggcat ttggagataa tggaaatcgt aaaaaaacta tgtttgagaa
    15541 aataaccttg tttatcgtga ttatcatgct agtagcaagt ttattgggaa tttttgcaac
    15601 tgcaattggt gccctcagta atctataaaa tagattcaag aaaatttagt gactgggatt
    15661 tcccagccct tttttaaagt gagaagaaat aatgagtatg tttttagata cagctaagat
    15721 taaggtcaag gctggtaatg gtggcgatgg tatggttgcc tttcgtcgtg aaaaatatgt
    15781 ccctaatgga ggcccttggg gtggtgatgg tggtcgtgga ggcaatgtgg tcttcgttgt
    15841 agacgaagga ctacgtacct tgatggattt ccgctacaat cgtcatttca aggctgattc
    15901 tggtgaaaaa gggatgacca aagggatgca tggtcgtggt gctgaggacc ttagagttcg
    15961 agtaccacaa ggtacgactg ttcgtgatgc ggagactggc aaggttttaa cagatttgat
    16021 tgaacatggg caagaattta tcgttgccca cggtggtcgt ggtggacgtg gaaatattcg
    16081 tttcgcgaca ccaaaaaatc ctgcaccgga aatctctgaa aatggagaac caggtcagga
    16141 acgtgagtta caattggaac taaaaatctt ggcagatgtc ggtttagtag gattcccatc
    16201 tgtagggaag tcaacacttt taagtgttat tacctcagct aagcctaaaa ttggtgccta
    16261 ccactttacc actattgtac caaatttagg tatggttcgc acccaatcag gtgaatcctt
    16321 tgcagtagcc gacttgccag gtttgattga aggggctagt caaggtgttg gtttgggaac
    16381 tcagttcctc cgtcacatcg agcgtacacg tgttatcctt cacatcattg atatgtcagc
    16441 tagcgaaggc cgtgatccat atgaggatta cctagctatc aataaagagc tggagtctta
    16501 caatcttcgc ctcatggagc gtccacagat tattgtagct aataagatgg acatgcctga
    16561 gagtcaggaa aatcttgaag aatttaagaa aaaattgtct gaaaattatg atgaatttga
    16621 agagttacca gctatcttcc caatttctgg attgaccaag caaggtctgg caacactttt
    16681 agatgctaca gctgaattgt tagacaagac accagaattt ttgctctacg acgagtccga
    16741 tatggaagaa gaagcttact atggatttga cgaagaagaa aaagcctttg aaattagtcg
    16801 tgatgacgat gcgacatggg tactttctgg tgaaaaactc atgaaactct ttaatatgac
    16861 caactttgat cgtgatgaat ctgtcatgaa atttgcccgt cagcttcgtg gtatgggggt
    16921 tgatgaagcc cttcgtgcgc gtggagctaa agatggggat ttggtccgca ttggtaaatt
    16981 tgagtttgaa tttgtagact aggagactgg tatgggagat aaaccgatat ctttccgaga
    17041 tgcggatggt aattttgttt ccgccgcaga cgtttggaat gaaaagaaat tggaagaact
    17101 atttaatcgt ctcaatccaa atcgtgcctt gagattggca cgaactaaaa aggaaaatcc
    17161 atctcagtaa agaagctaaa aaatcccgtg cctcatcaga cacgggattt tgtggtacga
    17221 caggcatgta tagcaaactg aatctggaat agcacagcat atcttctaaa atattgctat
    17281 aaattgattt gaatttcaaa attaaattgt tttattctta tttcaatttg ttatagtata
    17341 tctgatgtca aagttctcgg cgagtcaaat agtgattccc aagcctgact atcgtgaggt
    17401 agcggattaa aatggtctgg ggatagaccg ttttaagtct gatgctggaa ataagaattg
    17461 tcagaagaag ggatagcgaa atcgtggctc tacgaacagg aacgtgataa taaggcgtat
    17521 atagcgaata agagggcctc aaactctaaa gtccaaaaag gtagtcgtaa cctatatgcg
    17581 taaatcatga gagtaattga attcgtacta agattttcta tttttactgt aaccttttaa
    17641 cgtcctcata tcttgtatac acgaggaaag atgtacgact tatcccgtga ggtctatcac
    17701 tataaagaga aaacgacaga tagaagtgat cctgagtcac ggttatcttt aaaatagatt
    17761 gtctgatagg atgctagcct gaaaacgtct tgttcatgaa atataggacg gtatgtataa
    17821 aacgcttctg tgaactgaga gaagggggag aagttcttgc taaaatttag ttgaacagcc
    17881 gtattccgat acttagataa gagatctagt cttagctcct actcagtttc aggggataaa
    17941 aaaggggcaa tagcgattcg agaaagatta tactcttcga aaatctcttc aaatcacgtc
    18001 aatatcgcct tgccgtatgt gtaggatact aactacgtca gttccatcta caatctcaaa
    18061 acagtgtttt gagcaacctg cggctagttt cctagtttga tctttgattt ttattgagta
    18121 ttagtaattc agttactaac tcgtcaactc tgatttatcc aataaaattg aaaaggatgg
    18181 aaaaaaggat aaatttatga tatactttat tttgaagacc ttattagaaa tcttgaaaga
    18241 gtattgaaaa cttagaatga gaaaaattgt tatcaatggt ggattaccac tgcaaggtga
    18301 aattactatt agtggtgcta aaaatagtgt tgtggcctta attccagcta ttatattggc
    18361 tgatgatgtg gtgactttgg attgtgttcc agatatttcg gatgtagcca gtcttgtcga
    18421 aatcatggaa ttaatgggag ctactgttaa gcgttatgac gatgtcttgg agattgatcc
    18481 aagaggtgtt caaaatattc caatgcctta tggtaaaatt aacagtcttc gtgcatctta
    18541 ctatttttat gggagcctct taggccgttt tggtgaagcg acagttggtc taccgggagg
    18601 atgtgatctt ggtcctcgtc cgattgactt acaccttaag gcgtttgaag ctatgggtgc
    18661 cactgctagc tacgagggag ataacatgaa gttatctgct aaagatacag gacttcatgg
    18721 tgcaagtatt tacatggata cggttagtgt gggagcaacg attaatacga tgattgctgc
    18781 ggttaaagca aatggtcgta ctattattga aaatgcagcc cgtgaacctg agattattga
    18841 tgtagctact ctcttgaata atatgggtgc ccatatccgt ggggcaggaa ctaatatcat
    18901 cattattgat ggtgttgaaa gattacatgg gacacgtcat caggtgattc cagaccgcat
    18961 tgaagctgga acatatatat ctttagctgc tgcagttggt aaaggaattc gtataaataa
    19021 tgttctttac gaacacctgg aagggtttat tgctaagttg gaagaaatgg gagtgagaat
    19081 gactgtatct gaagacagca tttttgtcga ggaacagtct aatttgaaag caatcaatat
    19141 taagacagct ccttacccag gctttgcaac tgatttgcaa caaccgctta cccctctttt
    19201 actaagagcg aatggtcgtg gtacaattgt cgatacgatt tacgaaaaac gtgtaaatca
    19261 tgtttttgaa ctagcaaaga tggatgcgga tatttcgaca acaaatggtc atattttgta
    19321 cacgggtgga cgtgatttac gtggggccag tgttaaagcg accgacttaa gagctggggc
    19381 tgcactagtc attgctgggc ttatggctga aggtaaaact gaaattacca atatcgagtt
    19441 tatcttacgt ggttattctg atattatcga aaaattacgt aatttaggag cggatattag
    19501 acttgttgag gattaaaccg tagaggtgtt tatgaatatt tggaccaaat tagcaatgtt
    19561 ttcttttttt gaaacggatc gcttgtattt gcgtcctttc ttttttagtg atagtcagga
    19621 cttccgcgag atagcttcaa atccagaaaa tcttcaattt attttcccaa cgcaggcaag
    19681 tctggaagaa agtcaatatg cactggccaa ttactttatg aagtcccctt tgggagtgtg
    19741 ggcaatttgt gaccagaaaa atcaacaaat gattggttct attaaatttg agaagttaga
    19801 tgaaatcaaa aaagaagctg agcttggcta ttttttgaga aaagatgctt ggtcgcaagg
    19861 atttatgaca gaggttgtta gaaaaatttg tcagctttct tttgaggaat ttggcttaaa
    19921 acaattattt atcattaccc accttgaaaa tgaagctagc caaagagttg ctcttaagtc
    19981 tggatttagt ttgttccgtc agtttaaggg aagtgatcgt tacacaagaa aaatgcggga
    20041 ttatcttgaa tttcggtatg taaaaggaga gttcaatgag taagcatcag gaaattctaa
    20101 gctatttgga ggaattacca gtaggtaaaa gggtcagtgt tcgtagcatt tcgaatcatc
    20161 taggagttag tgatggaaca gcctatcgag ctattaaaga agctgaaaac cgtggaattg
    20221 tggagacccg tcctagaagt ggaacaattc gtgttaaatc ccagaaagtt gctatagaga
    20281 gattaacgtt tgctgaaatt gcagaagtga cttcttctga ggttctggct gggcaagaag
    20341 gtttagagag agagtttagt aagttttcaa ttggtgccat gactgaacaa aatatcttgt
    20401 cttaccttca tgatgggggg ctcttgattg tcggagaccg aacccgtatt cagttgctag
    20461 ccttggaaaa tgaaaatgca gttctggtta cagggggatt tcaggttcat gatgatgtgc
    20521 ttaaactggc caatcaaaaa gggattcctg ttctaagaag taagcatgat acctttaccg
    20581 tcgcgaccat gatcaataaa gccttgtcaa atgtccaaat caagactgat attctgacag
    20641 ttgagaaact ttatcgccct agtcatgagt atggttttct gagagagaca gatacagtta
    20701 aagattattt ggacttggtt cgtaagaatc gtagcagccg tttccctgtt atcaatcaac
    20761 atcaggtcgt tgttggtgtt gtaaccatga gagacgctgg tgataaatca ccaagcacga
    20821 caattgataa ggttatgtct cgtagtctat tttgggttgg attatcgaca aatattgcca
    20881 atgtgagtca acggatgatc gcagaagact ttgaaatggt accagttgtt cgaagcaatc
    20941 aaactttgct tggcgttgtg acgcgacgag atgtcatgga gaagatgagc cgttcccaag
    21001 tttcggctct accaactttt tctgagcaga ttggacaaaa gctctcttat caccatgatg
    21061 aagtagtcat tacagtggaa ccctttatgc tagaaaaaaa tggagttttg gctaatggtg
    21121 tattggcaga aattctgacc cacatgaccc aagatttagt tgttaatagt ggtcgcaatc
    21181 tcattatcga gcagatgctg atctactttt tgcaggctgt tcagatagat gatatattgc
    21241 gcattcaggc acggattatt catcatacga gacggtcagc tataattgat tacgatattt
    21301 atcatggtca ccagattgtt tcaaaagcaa atgtgactgt taaaattaat tagaaactag
    21361 gagaaaagat gataacatta aaatcagctc gtgaaatcga agctatggac aaggctggtg
    21421 attttctagc aagtattcat ataggcttac gtgatttgat taagccaggc gtagatatgt
    21481 gggaagttga agaatatgtc cgccgtcgtt gtaaagaaga aaatttcctt ccacttcaga
    21541 ttggggttga cggtgccatg atggactatc cttatgctac ctgttgctct cttaacgatg
    21601 aagtggctca cgctttccct cgtcattata tcttgaaaga tggtgatttg ctcaaagttg
    21661 atatggtttt gggaggtccc attgctaaat ccgacctgaa tgtctcaaaa ttaaacttca
    21721 acaatgttga acaaatgaaa aaatacactc agagctattc tggtggttta gcagactcat
    21781 gttgggctta tgctgttggt acaccgtccg aagaagtcaa aaacttgatg gatgtaacca
    21841 aagaagctat gtacaagggt attgagcaag ctgttgttgg aaatcgtatc ggtgatatcg
    21901 gtgcggctat tcaagaatac gctgaaagtc gtggttacgg tgtagtgcgt gatttggttg
    21961 gtcatggtgt tggcccaact atgcacgaag aaccaatggt tcctaactat ggtattgcag
    22021 gtcgtggact ccgtcttcgt gaaggaatgg tcttaaccat tgaaccaatg atcaatacag
    22081 gcgattggga aattgataca gatatgaaaa ctggttgggc gcataagacc attgacggtg
    22141 gattgtcatg tcagtatgaa caccaatttg tcattacgaa agatggacct gttatcttga
    22201 ctagccaagg tgaagaagga acttattaat aaaaagtgaa aagactactg gaagtttatt
    22261 ttgataaaaa atccagtaga tcttttcata ataaaacgca ttgtatcaag tgttaggagc
    22321 tgatatcatg cgtttttctg cttttaagat tttttccaac tctgtttgta agcgcatcat
    22381 aacaaagggt ctaggattca gggctctcct cctatatact attagtaaag taaaactaag
    22441 agaggatatt ttagtgtcgc agtctattgt tcctgtagag attccacaat attgtcgttt
    22501 tgattctaaa aagagaaatg gaattctgtt taacgttcgt attgccaatc ttaaatttac
    22561 cttttttaga ttagacttcc tgcgaaa
//
LOCUS       DBEJJV010000031        22428 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.031, whole genome shotgun sequence.
ACCESSION   DBEJJV010000031 DBEJJV010000000
VERSION     DBEJJV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.031"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(14..532)
                     /locus_tag="ACL3GT_001457"
     CDS             complement(14..532)
                     /locus_tag="ACL3GT_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HGR0517113.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(569..697)
                     /locus_tag="ACL3GT_001458"
                     /pseudo
     CDS             complement(569..697)
                     /locus_tag="ACL3GT_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CD1845 family protein"
     gene            complement(759..1628)
                     /gene="rsmI"
                     /locus_tag="ACL3GT_001459"
     CDS             complement(759..1628)
                     /gene="rsmI"
                     /locus_tag="ACL3GT_001459"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HGR0517114.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(1631..1948)
                     /gene="yabA"
                     /locus_tag="ACL3GT_001460"
     CDS             complement(1631..1948)
                     /gene="yabA"
                     /locus_tag="ACL3GT_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HGR0517115.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(1988..2878)
                     /locus_tag="ACL3GT_001461"
     CDS             complement(1988..2878)
                     /locus_tag="ACL3GT_001461"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HGR0517116.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLAHQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(2875..3513)
                     /gene="tmk"
                     /locus_tag="ACL3GT_001462"
     CDS             complement(2875..3513)
                     /gene="tmk"
                     /locus_tag="ACL3GT_001462"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HGR0517117.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTNAVLFDGMGLAK"
     gene            complement(3629..4426)
                     /gene="proC"
                     /locus_tag="ACL3GT_001463"
     CDS             complement(3629..4426)
                     /gene="proC"
                     /locus_tag="ACL3GT_001463"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HGR0517118.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGIVMEAVHQAYKRTQELGK"
     gene            complement(4430..5692)
                     /locus_tag="ACL3GT_001464"
     CDS             complement(4430..5692)
                     /locus_tag="ACL3GT_001464"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HGR0517119.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(5702..6811)
                     /gene="proB"
                     /locus_tag="ACL3GT_001465"
     CDS             complement(5702..6811)
                     /gene="proB"
                     /locus_tag="ACL3GT_001465"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HGR0517120.1"
                     /translation="MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHEL
                     ILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILL
                     TQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQ
                     ADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIK
                     AATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQG
                     SIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKGRVQFGAS
                     ALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(6912..8795)
                     /gene="cbpE"
                     /locus_tag="ACL3GT_001466"
                     /gene_synonym="pce"
     CDS             complement(6912..8795)
                     /gene="cbpE"
                     /locus_tag="ACL3GT_001466"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HGR0517121.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVARHHYYLEESGAMKQGWLKKAN
                     DWYFYKTDGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(8798..9685)
                     /locus_tag="ACL3GT_001467"
     CDS             complement(8798..9685)
                     /locus_tag="ACL3GT_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0517122.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(9675..10136)
                     /gene="lspA"
                     /locus_tag="ACL3GT_001468"
     CDS             complement(9675..10136)
                     /gene="lspA"
                     /locus_tag="ACL3GT_001468"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HGR0517123.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10133..11041)
                     /locus_tag="ACL3GT_001469"
     CDS             complement(10133..11041)
                     /locus_tag="ACL3GT_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HGR0517124.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11034..11231
                     /locus_tag="ACL3GT_001470"
     CDS             11034..11231
                     /locus_tag="ACL3GT_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HGR0517125.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(11282..11953)
                     /locus_tag="ACL3GT_001471"
     CDS             complement(11282..11953)
                     /locus_tag="ACL3GT_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0517126.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12007..12228)
                     /locus_tag="ACL3GT_001472"
     CDS             complement(12007..12228)
                     /locus_tag="ACL3GT_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HGR0517127.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCSRGTYDLGYIGGGNHLCKGSAARF"
     gene            12500..13309
                     /locus_tag="ACL3GT_001473"
     CDS             12500..13309
                     /locus_tag="ACL3GT_001473"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0517128.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLELDLQNEYIIVNNGCSTHQTSDWSLVDWKELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(13490..14365)
                     /gene="aguB"
                     /locus_tag="ACL3GT_001474"
     CDS             complement(13490..14365)
                     /gene="aguB"
                     /locus_tag="ACL3GT_001474"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0050126 - N-carbamoylputrescine amidase
                     activity [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HGR0517129.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGGVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(14375..15460)
                     /gene="aguA"
                     /locus_tag="ACL3GT_001475"
     CDS             complement(14375..15460)
                     /gene="aguA"
                     /locus_tag="ACL3GT_001475"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047632 - agmatine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0009446 - putrescine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HGR0517130.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(15457..16584)
                     /gene="nspC"
                     /locus_tag="ACL3GT_001476"
     CDS             complement(15457..16584)
                     /gene="nspC"
                     /locus_tag="ACL3GT_001476"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0045312 - nor-spermidine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HGR0517131.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(16584..17843)
                     /locus_tag="ACL3GT_001477"
     CDS             complement(16584..17843)
                     /locus_tag="ACL3GT_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HGR0517132.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(17840..18700)
                     /gene="speE"
                     /locus_tag="ACL3GT_001478"
     CDS             complement(17840..18700)
                     /gene="speE"
                     /locus_tag="ACL3GT_001478"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HGR0517133.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            18956..19560
                     /locus_tag="ACL3GT_001479"
                     /pseudo
     CDS             18956..19560
                     /locus_tag="ACL3GT_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846390.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            19540..19665
                     /locus_tag="ACL3GT_001480"
                     /pseudo
     CDS             19540..19665
                     /locus_tag="ACL3GT_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(19637..21112)
                     /locus_tag="ACL3GT_001481"
     CDS             complement(19637..21112)
                     /locus_tag="ACL3GT_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HGR0517134.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNSEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEKVIELSEYARREINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            21819..>22428
                     /locus_tag="ACL3GT_001482"
     CDS             21819..>22428
                     /locus_tag="ACL3GT_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR0517135.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRRTVRQCLGKGRFKEVYSADYAQQSYENNRKHSVKRSSVTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRPEAINLRLENGHYEIDTVLLTRSKNYCLLVLTDRKSRH"
BASE COUNT         6580 a         5161 c         4032 g         6655 t
ORIGIN      
        1 ttaaaaatat aatttataat actatcttct tccattttct gattttagtt ctgaaagttc
       61 caaaaggtgc aaccgtattt acatgaataa acttatacac ttcccaagtc gctgttttag
      121 tcgcttcatc agcccacttt ctcatatgcg gttcaaataa ttcttcctca ctcaacgaat
      181 caatcattgc agagatagaa ttaatatttt catttaattt tgctttcaac tcttgcagag
      241 ataaatgagc gtaggtatct gtgaaccact gatataattc accaagttga ttccatttaa
      301 atttatccga tggtgttttt acttgaagcc cctttctttc atcttcttcc catttaagaa
      361 ccaagttggt ccaaccaacc tgataagcaa ggttttctgc tggagttctg tcaacttcat
      421 cagctctctt atcttttaaa ttttctggaa tattatcaaa ttctaaaata tatttctcaa
      481 atgttttctc tatctcagct tttagttctt ctttattttc gtatgttcgc aaaaaatcac
      541 cttctttctg atttatcaat cctttgattt aaaatgacct tatttttcta tttatacctt
      601 ctaagaacgc tataactgct gctccaacca tcggtattcc gtatgggctt aataaaaaac
      661 ttaataccaa agcttctata ccaagtgata catctttata ttatcatcac taattaagtt
      721 aaacagaaac agacagaatt attacatcct atctcccttt attgtttttc ttcccagtcg
      781 tggtaggcag cgtagagttg actcttattc cactggtaaa tcttagctac ttccttaata
      841 gcttgatttt tcttcatacc ttgctggatg cgggtttgaa tttctacgaa caagtcttcc
      901 tcgtcctttt cctccacacc ctgactggca ccctcaacaa tgagaagaca ttcgcccttg
      961 agtggcgttt cagcaatgct ttctaataac tcagagatag tacctcgttg gtattcttca
     1021 tagattttgg tcaattccct gaccaagaca acggagcggt caccgtagac ttctaacata
     1081 ttttccaacg tgtctgctac acgatgaggt gattcataaa aaatctgtgt ttcaggataa
     1141 tcttttttca agccaaaaaa ttgcttctgc tgacctgatt ttctcggtaa aaaaccgtaa
     1201 aagatatgtg gctgtggcgc taaaccactg gcaatcaagg cagaaattcc tgcagaggca
     1261 cctggaactg tcacaactgc aatttcttcc tcaatagctg ccttaactaa atcatgacca
     1321 gggtctgaaa tgctaggcaa accggcatca gagacctgag caatactttg ccctgctttc
     1381 aagaaaccaa tcaaatcagg aattttttcc ttggcattgt gctcatgaaa actgatctgc
     1441 ttggtggaaa tgtcaaaatg cttgagcaaa agacctgtat tgcgcgtatc ctcagcagca
     1501 atccaatcta cttctttcaa ggtctggata gctcgaaagg tcatatcatc tagattgcca
     1561 atcggcgttg ccactagata cagcttgcca tagggagact gccccttaaa acttttttga
     1621 atctgcatgc ctactccctg tatagcaact cgtcacaaaa catacattcc tcgtcctgct
     1681 ctcgacgttg tccataaaaa tcattacata cgtgaaatcc atcacggtaa atgcgacgga
     1741 cactttcacg aacatgcttg gccttgacag gagcatctgc ttccacctca cccaagcgtt
     1801 ctcgcaactt agaattttcc aaacgaagag ctgtattttc ctctaccagg ctcttgagat
     1861 ttttcttgat ggcttccaca tcggccaagg ttaccaataa ctgttgggaa aaatcatcca
     1921 gcgcgtcaaa taattctttt ttgtccataa aacagccctt tcctttcttt atcattcatt
     1981 tttgagttta tatttctttc aagaccagat attccatggc attttgaaag ctgacattag
     2041 cttgccacat ttttctagct tctagtaaat cttgtagaat cactcttact cttacctgca
     2101 agaggtcctg cccacagaga acttcaagaa tccgtaaaac ctgatcctgt ttttccttat
     2161 catctgccaa gttggctaat ttggcaacct gtagataact ttcttttttc ttagctacta
     2221 accaagtcag caggcgttca ctttcatcga ccaaggtcca aaaacttgcc tgatgtgcca
     2281 acttttctgc ttcagctcgc gattgactaa acttagctaa aagagtcgct tttttcttaa
     2341 caagtcccat ttgttctaag agtaagataa gtttttcttc ttgcttttta aagtggaaga
     2401 tctgagtccg acttcggatt gtcggtaaca tcttttcctc atcgctagtc aagaagaaaa
     2461 tataaacttc actctggggt tcttcgatga ccttgagcag agaattggct gcgttgggat
     2521 gcattttatc cgcttgctcg atgataaaga cctgttgctg gctttcaatc cctgcttgag
     2581 aaaactgtcc caccaattcc cgaatacgtt ctgtcttgat gacctgattg actggcttaa
     2641 tcaaggtgac atctggaaac tcttcctgtt caatcagctt gcaacttcgg catttctcac
     2701 atggtaagac gccaacttta tccgtacaaa aaaggctctt agctaaaaat tgcgccattt
     2761 ccaagcttcc aaagaaacct gaaaagagat aggcgtgatt gagctggtct tgttctaaga
     2821 tacggacaaa acggtcaaac tgagctggtt gccaagcctt tagttgatct tgtttcattt
     2881 ggccaagccc attccgtcaa acaagacagc attggtagtt tccacaactt gctccaaagg
     2941 gagactagca tcaatcttga caatgcgatt tccctcttta tccagaagag aaaggtagcc
     3001 ttgacgaact tttttatgca agtccaaccc ttccaaatcc aaacgattaa cctcgcggtc
     3061 actattagca gcaatacgag ccagcccttc ttccacctcg atgtcaaaat agagtgtcaa
     3121 atcgggtttg aggccatctg tcgcaaactg attgagccag tcaatggctt caatatctaa
     3181 gccacgacca aatccctgat aggcaacaga actatcgata aaacgatcca tgatgaccaa
     3241 cttgccagct tcaagggctg gaagaacttt ttccaccaaa tgctgtctgc gactggcaat
     3301 atagagaagt agctctgttt tagcatccat ctgagtatga cttggatcca aaatcacttc
     3361 ccgaatcttc tccccaatca agactccgcc aggttcacgg gtcgtcagca cctctactcc
     3421 tttttcctct aaaattggta gcagagcctc taaaacactg gtcttgcctg ctccctctgg
     3481 tccctcaaga gagactaaaa atccttttga catgtctaac tcatttcttt tttactactt
     3541 ctattctatc aaaaaaatag gagtttgtga caatcttttt gtgtcttctc atttcagcca
     3601 ccataaaaga ggcagtcaaa gctacctctt atttacctag ttcttgtgtt cgtttatagg
     3661 cttgatgaac tgcctccatg actatgcctc gaaaagcatg cgcttctaag cttgctacgc
     3721 cagcaatagt cgaaccgcct ggactacaaa cttgatcttt caaaactcca ggatgttgct
     3781 ggctttctag gaccaattgc ccagctccta ccacagtttg ggctgccatt ttcaaggctg
     3841 tttctcgtgg taatcccgtc tgaacacctg catctgccaa ggcctcaata aagagataga
     3901 caaaggctgg tccacaacct gcaagacctg tcgctgcatt gattaagctt tctcctaatt
     3961 caaccaagag accagccttg gctaaaagct gacaaaagat ctcactgtcc tcagccctgc
     4021 aattaggaga caaggcataa ctaatcactc cttgcccgat agaagcaggg gtattaggca
     4081 tcatacgaat aattcggtgt tggcttggga taagacttgc tagtttttct aaggtcaatc
     4141 cagctgccat cgaaatcaaa agaagacttt ctcttttttc aaggatggtc tgatattgag
     4201 aaagcagttc agaaaactga gcaggcttaa ctcctagaaa aatcacatct gcttctgcaa
     4261 acatttcttc attgctggaa gcctgaccac caaagtctgc aatgaaagca tctaccttag
     4321 cttgactacg attggcaagg agaatctcat ctgacgtcct agtctgcaag acagattttg
     4381 ccaagctagc acccatattc cccaaaccga taaatccaat cttcatctct tactccctta
     4441 tctgcccatc accagcaacc acatacttgt agctggtcaa ctctttcaag cccattggac
     4501 cacgcgcgtg caatttctga gtagaaatcc ccatttcaca accaagacca aattgtcctc
     4561 catctgtgaa acgagttgag gcattaacat acaccgctgc agagtccact tgatctgtaa
     4621 agtatgctgc agcttcagca ttttccgtca caatagcatc cgaatgatgg gtactgtggg
     4681 attcaatatg cgcaaccgct tcttctaaac tgctcacaac cttaacagct agaatatagt
     4741 ctaaaaactc ggtatcaaag tcttgtgctt gagcagcttg acctgaaaca aactggcttg
     4801 ctttgctatc taggcggaat tgaattggtt ccaacccagc ttcttttcga tctgcaacca
     4861 gcatttgatc caagcgagga aggatgcttg ctgccttgtt ttcatgaacc agcagaacct
     4921 ccatggcatt acaaacagaa ggacgactgg ttttagcatt gttgatgata gacagcgcct
     4981 tgtcttcgtc tgcatcctta tccacataga catggacaat cccagtccct gtctcgataa
     5041 caggtacaat cgcattctca accactgcat tgatcaagcc agctcctcca cgaggaatga
     5101 gaaggtctag atagcccttg gccttcatca tagcataact actttcacgg ctagtatcct
     5161 ccaccagttg aatcacattt ggatgaatag tagtcgtctc caagcccttc ttcaaggctg
     5221 tgacaatggc atgggttgtt tgataggcat ccttaccact acgaagaaca accgcatttc
     5281 cactcttaag agtcaaagca gccgcatcag acgtcacatt tggacggctt tcatagataa
     5341 taccgatgac acccatagct acacgttttt ttgtgataac caaaccattt tcaagctgac
     5401 ttgtttctaa aacttcaccg attggatctg gtaaggcaac cacttcacga attcctcttg
     5461 ccatcgcttc tatacgatct gcatccaaat aaagacgatc caacatcaca tctgagattt
     5521 tccccttagc cgctgccata tcgagggcat tagccgctaa aatttcctca gtagcagcca
     5581 ctaagtgatc agccatggct agcaaggctt ggtttttcac ttcttcacta gctgtgttaa
     5641 tcgatttttt aacagcctgt acctgttcaa attgttcttg tctactcacc atagtttacc
     5701 tctaaaattc tgtaaaaagt agttggattt caggagtaat ggaaatccag tcgtcacggt
     5761 aaatcaagac acccttggct ttttgagaac gcaacatatc ctccaaagca gatgctccaa
     5821 attgcacgcg tccttttcca agtgattttc cactttcctt atcaaatact gtcacgatat
     5881 caccgtaaga aaagactcct tctgcttcaa cgataccaga taagagaaga ctctttccat
     5941 gttgagagag agcttccgca gcccctttat caacccaaat agaaccttga ctctgagcat
     6001 agaaggcaag ccattgtttc tgggtacgaa gccccttctc ttgagcaaca aagtaagaac
     6061 catcctcggt ctcctctgcc gcctcaatca tggaatctga tttcaaggat gagcagatat
     6121 aaacaggaac tcctgattcc gtcgcgatag ttgcagcctt gattttggtt aacatacccc
     6181 cagttccgtt tgacgaacca gctccaccag ccatatcaat aatctcacga ttgatggtct
     6241 cgattctctc caagcgtttg gctcttggat ctgaattagg atttccagta tagagaccgt
     6301 ccacatctgt caagaaaact aaaaggtctg cttggaccat cgccgctact tgagcactta
     6361 gagtgtcatt gtccccaacc ttgagctcat caataacgac actatcattc tcattgatga
     6421 taggaattgc cccacggttg agcaaaaccg acaaagcctg atgggcattt ttataacgac
     6481 gcttatccac aaagtcatct tgggtcagca agatttgtgc agaaacgatt tgacgcaaga
     6541 gaagattggt cgtatattct tccaacaaaa gtccctgccc taccgctgct gaagcctgtt
     6601 tatcagcaat tttagtcgga cgctttttaa atcctaaggc tccaaaacca gccgcaatgg
     6661 cacctgaaga caccaaaatc aactcatgac cagcctcgtg cagcatagcc aactgctggg
     6721 taatatcctt taccttacta cgtgataaac ttccatcctc atttgtcaga gaagaagtac
     6781 ccaccttaaa gacaatccgt ttgtatttca tagtctcact ccgattattc atatttatcc
     6841 attataacat gaataacagg aaatagaaaa gagttgatag gaaaaagaag gccctaaaac
     6901 cttcttttct actactgttc tgattccgat ttgtttacac tcgtttcaga gctttgtgaa
     6961 gttgaggatg tcaaatcttg actagttgaa gaatttgtaa cactttcatg ttgactcgtt
     7021 tctttatttt caagatcctt tttcactact tctttggatt cttttatttc tgaatgactt
     7081 gtagttttaa ttgtagcaga tttctcgatc ggaacatcca ctaaccaggc accacttgaa
     7141 tccacagtat agccttctgg tgtcttacca ttcacaagta attgaccatt ttctttcaag
     7201 aagtaccatt tatccttgtc tttaatccaa cctatagctc gtgaaccatc tgtcttgtag
     7261 aaataccaat catttgcctt tttaagccag ccttgcttca tagctcctga ttcttctaga
     7321 tagtaatgat gtctagcaac ttctatctca cctgtcttca tgataccagt agaatccata
     7381 tagtaccagg cttctttatc ttttacccag cccgttttca tttcccctga tggagcaaag
     7441 taataccatt gccccttata ttgaagccaa cctgtcttca tagagccatc aacatccaaa
     7501 taataccact gctctttatc ttgaatccaa ccaatttcca tctggttttc tttgttaaaa
     7561 taataccaga ttccagcgat tttcttccaa tttttagcag caacaccaga gtctgtcaaa
     7621 tagaaccaac gattgttcca ttttttccat tgattctgta ataagatacc cgtttggtta
     7681 aagtaatacc attcaccctt aatttcattc caaccgacag catattctcc tgtagaatca
     7741 ggcgcttgat accaccagtt tccatatgaa ctcttatgcc aaccagcttg aaaacttgga
     7801 atcggcttgt aggaagttga aatgtttact aaaccgtctt gtcgaatatc aaaaactgtt
     7861 gcatcatagt ctttgctggc tgcattgatt ctctcaattc ctcgttcttt gagccaatta
     7921 acatactcac tatcaacacc atttttccaa ggtagactat ccgaagtttg aacaatcaaa
     7981 ctcggactca aatttttaat gaaatccttg gtatttgatt tgttggtatc atggtgatga
     8041 ttaaacttca tcaaatcaac ttttccaatg agaggaccat acttgtcttc tgctccatga
     8101 acattatcta aatcgccccc aaggtaaatt ttcttgccat tgactttcac cacgctaatc
     8161 aaggaattgg aattgtcatc ccaaattttc tttaattcac ccgatgaatc agtttcattt
     8221 tcataattat agagctgaat atccatgtcc ccaaactgaa aatgagcatc cccttgtgtg
     8281 atattttgaa taactgaaac acctttttct gcagcagtct gtaaaacctt atcatagcca
     8341 tacagattat cccatagacg ttcagaatta gtaatacgac tatcactata tttcttaaga
     8401 tagactcggt caactggata ggtagacagt aattcatcaa catttccaat atgatcactg
     8461 tgggtatggg tcaccaaaat aaaatcaagt ttttggacac ccaattcctt caaacgacga
     8521 aagacacggt ctgttagaac atgcttataa gacgtttcaa ttccttctct ccatggatag
     8581 cgagaatcac ttccatctgg gaaatcataa tcttctcctg tatccaccat ggcaaaatgt
     8641 ccattgcttt caagaataat cgcatcactg ccaccttctt gaacattgat aaagtggatt
     8701 ttatttcctg aactttcttg agcctgaaca ttcccatacc atgacaaacc taaaaaagcg
     8761 cctacaagtg ctaaactagt taatttcttt ttcattctta ctttctcaat ctctccaagg
     8821 tttccttaaa aatctctggg atatctgctt taaattccaa ggtcttacct gttctcggat
     8881 gagtaaaacc taaagtcttg gcatgaagaa attgtccatg tcctttcaaa gtcttgcgag
     8941 gaccatagac ctcatcacca gcgactgaat ggccgatata agccatgtgg acacggattt
     9001 gatgagtgcg ccctgtctcc agttgcaact ctactaagct ataatcgcca aagcgttcca
     9061 agacgtgaaa acgcgtcact gcaggcttcc ctttagcagt tacagcctgt ttcttacggt
     9121 ctttttcact ccggccaatc ggcgcttcaa ttacaccacg atcattaggc agatttccat
     9181 gaacaatcgc ccaatatttg cggagagact ttttatcttt gagttcttgg gcaagtacta
     9241 gatgcgcatc atcgttttta gcaatcatga gaagacctga cgtatcctta tcaatacggt
     9301 gaacaatccc tggacgcaga accccattga tacccgacaa gtccttaata tgatacatga
     9361 gggcatttac tagggttcca ctggtatgac cagcactcgg gtgcacaacc attccctgag
     9421 gtttgttaac gacagccaca tcctcatctt ggtagactat ttctagcgga agatcctcag
     9481 ccacatactc taatacctct ggttctggca catggtaagt gacgacatca ccctcttgga
     9541 ctgtgtattt agctttcttg acttgaccat tgaccaagac ctggcctgat ttaatttgtt
     9601 cattcgcgag actacgtgat aattctgaca aatctgacaa agccttatcc aaacgcagac
     9661 caccagtttc aattttaatt tccatttatt tcctctttta gcattgcaat caataaaata
     9721 atcactccaa ccgtcagata gctatctgcc acattgaaaa ttgcaaagtt gataaagtca
     9781 aggtggaaca tatccacaac aaagccctga ctgaccctgt caataaagtt tccaagacca
     9841 cccgcgatta ttagagtcaa acccaagacc atccagaatg agtcctccat gtgtttatgt
     9901 aaataccaaa tggcacctat cacgacaacc agagtaatga cagcgaataa caactgctga
     9961 tcttgtaaga tagaaaaggc tgcacctcga ttttgcaggt aggtcaagct aacgaaattg
    10021 gggatccagg agcgcacttc acccagtgga atctgctgga cgatataaga tttgaccaac
    10081 tgatccagcc caattaaaag cagtacaatg actgccacta ttgctctttt tttcatgatt
    10141 tcctcttttg atcaaaatat tcttgcatga cttctacgaa gagagtccca gcttgactaa
    10201 gctccacttc ttcacgttta acatagacca tgcggttatc taggttatcc ttgagacgaa
    10261 taactgtaat gccattaaca ctgtcactat ctaaaaatcc agaacctgtc gcataggcgt
    10321 ccgtccgctc caaaatacca ttcaaggtgg cacggtctgt cacattaaac atctgtgagc
    10381 tagcgctggt atcgacaaag ttctctgaat aataaaggta ctcgtctttc tcttgagtga
    10441 aacgaaccgt tggtaaatcc gctaaatcct ccatgactaa ttcctctttc tgggctaaag
    10501 gatgaccctc acagagataa atatgggtat ggaaaggaat caattcgatg acctccagac
    10561 ctaacttttc aacccgttgc ataatcccct ttttattttg attgttgagg tagataatcc
    10621 caatctcact atgcccttgc gccacttcat ctaatatttg aacagtagtt gattcaaaaa
    10681 tacggaagtt cttatagtca ggatagcgct ctgaaaaggc cgtaatagtt ggtggtaaga
    10741 agtcatagtg ctggctagca acggaaaatt catctttttc ttcttcagga ttggcatact
    10801 gattttgaaa aatatcaaat cctttaacca attcttgcgc tttttcataa aattccatcc
    10861 cacgacgggt caagaaagtc cctgagctgg tccgacggaa aatcttaaag cccaactctt
    10921 tttccaaatc acgaacagaa atagacagac tcggctgact aacatacatc ttttcagcag
    10981 cttcacgaaa agtaccacta ttggcaatag ccacaacata gcgtaattgt tgaatgttca
    11041 tcttctaccc ccaacttctt tatcttttca ttataccata ttttagaagt tttccaaaaa
    11101 ggaaaaaaga acatcctatt cttcttaact atcttcacta tctgcctttc tcacgccaat
    11161 cttattttca aaatcaattc aaaaaaataa gtggctacac accacttcag tatcggaaag
    11221 aaaaacgttg actatttgtg aaaaaagaaa atgccggaaa attccgacat tttttagtaa
    11281 gctaacttcc tgaaaatagg agtaaccaaa catcccagaa ggcagtgata ttgatgagaa
    11341 tatgaactag tattggatag tagagatttt tagtcatgcg atacaataga gctaaaatca
    11401 gacctccact agcataaatg aaaaaagcaa gaggagttaa agcaaaattg atatgaatat
    11461 aaccgaaaat aatagcagaa agcaaaacat ctccgtacca aggtgagttt ttgaaaaagg
    11521 ttgtcataag cacacctcga taaatcaatt cctcagcaat aggggcgatg aagcaaacga
    11581 tgagcaagaa ataagggaac tcctgtctcc ccatcatttc tatcgtttca ttcaaagaaa
    11641 tctgatttga agacagggat atgaaatacg aaaagaggaa gtcagacata tatgaaatga
    11701 tgtagcccag taaaaggtag atgaagtacc tcagctgcca cttgaaatga aaaattttct
    11761 ttcctgcaaa aaccagtaga tagatgaccg ctaagaaaag aactccgctc tccatcaaaa
    11821 gcagaatctg aaaaaattca cgacttgctg gtagataggg ctttgcgagg tgattgaaaa
    11881 ctctccaaaa ccaagttgat ttgtaaaaaa ttaaggacaa tgctagtaaa atttgaatag
    11941 cccgtttttt catattaaat tctctgcttt ctccacttgt ttcttcatat tactaataaa
    12001 ttttacttaa aatctcgcag cacttccttt gcaaagatga ttgcctcctc caatatatcc
    12061 taaatcatag gtgcctctgg aacaaaatcc atgaaccggc agagttaata ctggttctat
    12121 ttcccaatcg tacctaccat taggattttt accatatgaa tctgctccac cttgtatcag
    12181 ctctaattct tcatttgtta gatttatatt ttttgtcatt aaaatcatga tatatttcct
    12241 ccattattct tcagattagt tgagtaatct gatactcata cctacttaca aaaaaactat
    12301 tatattaagt tggtttttta atttgtctag ttgcaacatt gacaaacata gtatagcata
    12361 tctttgccaa atatcctctt caaatcatga attgtcatca aaacatctta aactataaaa
    12421 tcaattagtc tcaagctttc tatcaatttc ttctccaaaa tatgctataa taatagcaaa
    12481 agataaagaa ggaagaccta tgattaaact actagccttg gatatggacg gcaccctcct
    12541 caatgaagcc aaggaaatcc cacaagctca cattactgct attcacaaag ccattgaaaa
    12601 aggtgtcaaa ctggttctct gtacgggtcg cccccttttc ggtgtcctcc cctactacaa
    12661 aaaactggag cttgacctcc agaacgaata tattattgtt aacaacggtt gttcaactca
    12721 ccagaccagt gattggagtc tagttgactg gaaagaactg agtccagctg acatcgaata
    12781 cctctatgac cttgctgaaa agagtgatgt tcagttgaca ctttttgacg agtcacatta
    12841 ttttgttctc ggtggcaaac ccaatcaagt tattgaaaat gatgctaaac tagtattttc
    12901 agacctgact gaaatttctc ttgaagaagc gactagtgga aagttccgga tgttccaagg
    12961 tatgttttta ggaacaaaag aacaaacaga cgattttgag cagcgttttg ctgaagagct
    13021 ttgccaacga ttcagtggag ttcgttcgca gcctgtcatt tatgaagcaa tgccgcttgg
    13081 aacgacaaag gctactgctc tttcacgact agctgagatt ttgaagattg attcctcaga
    13141 gattatggcc atgggcgatg ctaataacga tatcgaaatg ctccagtttg cagggcttgg
    13201 gattgcaatg ggaaatgcca gcgattatgt caaatctctt gcggatgccg ttacctcaag
    13261 caacgaagaa gacggcgttg cgcgtgctat tgagaaatat attctataaa aaagaaaagc
    13321 aaatagacag aagttactgc tatttgcttt tttgctaata ttttaaaata cggactaatc
    13381 aatagacaag aatagcgaat cataaaaatc gatttactag atgccatagt atcttatagt
    13441 tgctaataag aagttagtct agcagaatga atctctcatt tctcccacac taatctgtaa
    13501 tttgtctata catttctggt cttctatctc gaaacaagcc ccagtttaga cgttcacttg
    13561 ctcccttgtc taggtcataa gtagctaaca gaacagcttc ttcttgtctt tcagctcgtt
    13621 ctagaatagc tcctgtttca tccgtcataa aggaggaacc gtagaagtca agactggaac
    13681 tctgtccgcc attttcctca ctaggagtaa cctcctctaa accataacga ttggctgcga
    13741 tgactggaac aatattcgct gctgcgtgcc cttgcatagt acgttgccag tgaccacaac
    13801 tatctgtatc caaaattggc tctgaaccga tagctgtagg ataaaagagc aattcagcac
    13861 cattcaatgc aagacagcgg gctgtttcag ggaaccattg atcccaacag ataccgatac
    13921 caatcttagc atagcgagta ttccagacct tgaaaccagt gttaccaggc gtgaaataga
    13981 atttttcttg ataataatgg tcatctggta tatgggtctt tcgataaacg cccagcactc
    14041 ccccatctgc atcaatgacg gcaatagagt tatacaagac attaccatct ttttcataga
    14101 aactgattgg taaaacaact tgtagttcct tggcaatcac cttaaaatgc tgaatggcag
    14161 tattttccgc tacagattgg gcatactggt agtagtcata ctgacgttcc tgacagaaat
    14221 agggatgttc aaacaactcg ggcaagagaa taatttgggc tccttgctca gcagcctgac
    14281 gtactaaacg ctctgcggtt tggatatttg ttgccacatc cttagcgcat tgcatctgaa
    14341 tggttgcaac tcttacattt ctcatctttt tctcctattc tggaatttgt tgggtgatac
    14401 agtggatatt gccaccacct aagagaatat ctctggctgg tattccgaca actttacggt
    14461 ctgggaaaca cttgctgagg atatctaagg ccacttggtc gtttacatcc tcaaactgtg
    14521 gaaccaagac agccttgttg gcgatataaa agtttacgta ggaagctgct agtcgttcac
    14581 ctgcgtatcg ctcttcttct ccttcttcat agatgtagcc tggcaaatct tcttctgtca
    14641 caacttgtcg aactgcaggg ataggcaatt tatgaatggt gaagtgacaa ccttttgcat
    14701 ctgtttcctg ttctaagagt tcgagatctg cttttgacat ggcatactgg ggatcatttt
    14761 cgtcatctgt ccaagccaaa acaacctcag caggaccaac aaaggcaaca acattatcga
    14821 cgtgttcatt ggtttcatcc tgataaatac cataaggaag ccaaataact ttttcagcac
    14881 caagactttc taataatgtg ttttcaatct cctctttagt caggttagga ttgcgaccag
    14941 gactaagcaa gcaactttca gttacgagaa tagttccttg accatcgcta tggattgcgc
    15001 ctccttccag tacaaaaggt ttagcatcat agacaggcct ttccaaggcc tcagcaaaac
    15061 gactggctac ttggtcatcc tcttcataat cttgataaag accatcatag gtgcctcccc
    15121 aagcattaaa ggcccaatcc acggctaatt tcttaccttt atcattgacg agaatggttg
    15181 ggccagtatc acgcgcccag gcatcattgg tgggaatgtc taaataaaca accttgtctc
    15241 caagatagga ttgggcttca gatagatagg cctgctccac caaaagatag actctttccc
    15301 cttctgctat ggtctcgatg atctgagtaa atgctctttt agcagccttt ccttgaaaag
    15361 gccatgatcc tggtcgagtc ggccatatca tgagggtacc atgatggggt tcgtactctg
    15421 ctggcatgtg atagcctaat ttttttggac tgtccatcat gataatctcc ctttaaagtc
    15481 ttgatagcca aaagctttga gtaagctaca gtctccctgt tcgtccatga gatagagact
    15541 tggcaatcca ataccattaa aggtattatt tttgacaaaa gaataaatgg ccatgtcttg
    15601 aaaataaagt ctgtctccga tttggactgg attttcaaaa ctataatcac caatcacatc
    15661 gccagtcaga caggtattag aagaaagtct gtaggtatgg gctttttcct gtgactcaaa
    15721 gccatttctc aaaggtggac gatagggcat ctcaagtaca tcaggcatat ggcaggtcgc
    15781 agaggcgtct aaaaccaaga tttccatacc gttttctaca atatctaata cctcagttgc
    15841 taaataaccc gcattaagcg caatggcttc accaggctcg atatagattt caagattgta
    15901 agtttttcgg atacgcttga tttctgaaat cagcaaatcc acatcgtaac cttctcttgt
    15961 aatatgatga ccaccaccca tattgagcca ttttacctca tgtaagtagg gaccaaactg
    16021 ttcttctact gctttcaaag ttgtttgtaa atcatctgct ccctgctcgc aaagggtatg
    16081 aaaatgaagt ccgtcaacca aatctagcaa atcactcgga atcttgtcta tagtaactcc
    16141 aaagcgagaa ccaggtgcac aagggtcata gagcgcgtga tctccttgag ttgaacactg
    16201 agggttgagg cgcaaaccaa cactgacacc agcctctcga caacgagccc catgcttacg
    16261 caactgtctc tctgagttaa agacgatatg gtctgttatc ccaagcaatt cctccatgtc
    16321 ctcatccttg aaagctggtg caaaaacatg gacttcacca ggaaattctt cccttgccaa
    16381 tttggcctca tagagtccac tagctgtcgt acctgataga tactggctaa tcaagggata
    16441 agttttgtag agggaatatg ccttctgggc aagcaagacc ttgcaaccgg cctcttcttg
    16501 tacatattgt agaatgcggc aattagcttc taacttggcc aagtcaataa cataggctgg
    16561 tgttggtact tgttctaact tcattagtcc accatttgtg gattttcaac cacaacccat
    16621 ggcaaaccat actcattcaa agcttccatg aatggatctg gatctaactc ctcaaggtta
    16681 tacactccag cttgtttcca agttccgttc atgactaatt ttgtcccaat catggctgga
    16741 acgcctgtcg tgtatgaaat tgcttgtgac ccgacttctg catagcactc ttgatggtcg
    16801 caaacattgt agatgtagat agtcttttca acgccatctt tgacacctgt aaagatacat
    16861 ccaatattgg ttttacctac agtacgtggg ccaaggctag caggatctgg aagcaaggct
    16921 ttcaaaaatt gaattggaac aatttcttgg ccgttaaagt taatggtatc cgtacgaagg
    16981 agtccaacat tttcaagaca tttcatgtgc gtcaagtaag attgaccaaa agtcataaag
    17041 aaacgaatgc gtttgacacc tggaatgttc ttggccaatg attcgatttc ttcatggtga
    17101 aggagataca tatctttttg tccaacttga gggaaatcat actcacgctt gatagacata
    17161 gcttcgactt cgacccattt cccatcttcc cagtaagaac ctggcgcaga aacctcacgg
    17221 agattaattt ctggattaaa gttggttgca aatggataac cgtggtcacc gccattacag
    17281 tctaaaatgt cgatataatg gatttcatca aaatagtgtt tgagggcata agctgaaaag
    17341 acactagtta cacctgggtc aaaaccagaa ccaagaagag cagtcaagcc tgcttctttg
    17401 aatttctctt gataagccca ctgccatgag tagtcaaagt aggctgtaaa accaagttcc
    17461 ttacaacgtt tttcgtagat agcacgccac tcagggtctt ctgtgtcttc tgcttcgtag
    17521 ttggctgtat cgatatagtg aacacctgtt gccaaacaag catccataat ggttaaatct
    17581 tgataaggca gagctacatt caaaacagct tctggtttgt agctttcaat cagggcaatc
    17641 acttcttcaa ccttgtcagc atcaagtgct gcagtttcaa ttttagtact tgttttgcct
    17701 tctagcttcg ctttcaagtc atcgcatttt gacttggtac ggctagcaat cataatctct
    17761 gtaaatgttt cgctatcttg acaaatcttt gaaatagcaa cttgggcaac gcccccacaa
    17821 ccaataacta gtaaacgact catttttttc cttcctcttc ttctaaaatg tcctcaacat
    17881 acttgggcaa cataaaggat cccacgtgta agtttgcagt gtagtattct gtgaaaagct
    17941 ggcgtttttt ccaaccttcc ttgtcaaaat ctttgacagg gtggtatttt ttcgatgcaa
    18001 atccaaacaa ccaatagcca gctgggctag ttggaatatg ggcctgataa acccgactga
    18061 ttggaaaggc ttgattgacc ttgcggtgca tgcttcggca ggccgactca tcctcgtcaa
    18121 agaagggact cccatgctgg taaatcatga tgccgtcttc cttcagagct cgataactat
    18181 tgccgtagaa ttccttggta aagagtcctt ccgtatggcc aaatggatct gtcgcatcgt
    18241 tgatgataat atcgtaatca tcttcgcagt ttcgcaaaaa gcgtagccca ttttggtagt
    18301 aaatggtaac acgaggatca tctagccctg cagcaaagtc tgggaaatac tcacgacaga
    18361 cctcgaccaa catctcatcc ggttccacga tatcgatttg ttccagttca ggatagagtg
    18421 ttaatacttg ggcaacaccg ccgtcaccac ccccaataac caatactttc tttggatttg
    18481 ggtggacagc catgggaacg tgaacggtca tttcattgta gacgaaatca tccgcatctg
    18541 agaacaagac atggccattt aaaatcagta ttttcccaaa agctggcgta tccaagactt
    18601 cgatatcctg ccattcactt tttccagcgt aaagttgctt ggctgttctc agagacaatt
    18661 tgacatctgg agtatgaact tcagaaaacc ataaatccat ctatttctcc ttatattata
    18721 tttagcgcag ttagctactg ccaaagccca agtggtatac ttggaataag ccactgtgga
    18781 ttagtttatt ccctccaatc gcttgacgat ttccgaaagg ctctaaccac agttttttgt
    18841 ttcaattggt aatgagtttg ataacgcata gacgttttat ctcgtctaag gtaacaaggc
    18901 aaaaaattcg tggataacca agtagacttg aaatactaca tctggaggta ctcccatgct
    18961 ttatgtgggc attgatgtcg ctaaaaataa acacgatgtt acagccttga atgttccagg
    19021 aaaaactgtt cttaaaccac tcactttttc aaataataaa gctggttttg aactcttaga
    19081 tctgtctctt cgacaactca accaagactg tctcatcgct cttgaaaata ccggacatta
    19141 tgcctttaat ctactgaact tcctgcatga acaaggatat aaagtttaca cctacaatcc
    19201 tttgctcatc aaggaatttg ccaaatcatt atcacttcac aagactaaaa cggataagaa
    19261 agacgctcat ggcatcgctc ttaaacttct ttctgacccc aatcgtgaac aatttcaaca
    19321 cgataatcgg caagtagaac taaaaatact ggctagacat attcatcgtc tcaagaaaaa
    19381 cagtctgatt ggaaagtaca atacactcgt tgtcttgata tcatctttcc tgagttggat
    19441 aaaatcgttg gaaagcattc agaatatacc taccaactct tgacacgcta ccctaatcct
    19501 cagaaaagga ttgaggcagg atttgataag ctgatagaaa ttaagcgatt gaccgcttct
    19561 aattcaaggg ctttttgccg tgctctaaaa tcatcgccaa atcatcaaat tgaaataaga
    19621 aatagtttag ataaaactat tgacttttct tatagtttgt ctttctctta ataacgttga
    19681 tatgattgac ctctggatct tccgtccctt ggagggagca accacgttcc ttggcgaatt
    19741 ggatatagtc tacaatttct cgtgtaatgc gttcaccagg agccaagata ggaatccctg
    19801 gaggatagca catgacaaat tctccacaga cctgtccaac agactcatct aaggtcaaac
    19861 tttttctctc tgaatagaag gcttcttgtg gagacagcac caactcgggc tgaatatatt
    19921 ctcctgctat caaatctttt ccatctcttg aatagagtct cttaatatca gccagagcac
    19981 caaccaagcg ctcgatgtct tggatgcggt cgccgatgga aatataggcc aagatattgc
    20041 cgatatcacc aaactcgatc tgaatgtcgt attcgtctcg caagaggtca taaacctcga
    20101 tacctgttaa gccaataccc tgagtgtaaa ctgacagctt agttacgtca aaatcgcaaa
    20161 ccgaaacacc gtctattaac tcttttgagt aggcatagta gccaccgata gcattgattt
    20221 cacggcgggc atactcagat agctcaatga ctttctcaaa cgactcttta ccacgaaggg
    20281 ccaagttgcg acgtgaaata tccaaactag ccatcaacaa gtaagaggca gatgtagact
    20341 gagtcaggtt aattatctga cgaacgtatt cagaattcat ctgctccccg attaaaagaa
    20401 gcgaactttg tgtcaaactc ccaccagact tatgcatgga aactgctgcc atatcagctc
    20461 ctgcatccat agcagaaatt ggaagtttac cagtgaaatg caaatgcgct ccatgggctt
    20521 catctactaa aaccatcatg ccagcttcat gagccatttc tgtcaacccc tttaggtctg
    20581 aacagatgcc gtagtaagta ggattgttga ttaggatagc cttagcatct ggatggtcct
    20641 ttatggcctg tgctactcgg tcattttcaa gacctaaagc gataccaatc ttaggatcta
    20701 cactcatctc gatatagatg ggaatggcac cacatagaac caacgcattg atagcagatt
    20761 tatggacatt tcgtggcaga ataatcttat ctcctgcctt gcaggttgcc agaatcatag
    20821 tctgcaccga tgaagttgtt ccaccaatca ttagaaaggc atggctagct ccaaaagcat
    20881 ctgcagccag ctcctctgca tcacgaataa tcgaaatagg atggcctaaa ttatccaagg
    20941 gtttcatcga attgacatca atgcctacac atttttctcc taagagttcg acaagttctg
    21001 gatttccccg tccacgcttg tgacctggaa catcaaaggg aacaatcctt ttcttgcgta
    21061 acttcaccaa ggcctcataa attggggctt ggttttgatc taactctttc aaaacatact
    21121 cctttcaata tttttaggac cttatgaaaa ctaaggaact aaaggttgac tcatgaaaaa
    21181 agagcaggtt ttcacctgct ctgcaatctt ctgacgtgtt tattttggtt tctgttgagt
    21241 atgtctgttc ccgatgtttc ctaactctct agtagcaaat attacgtact ttattgatcg
    21301 tttcacaaga tgacgtgtgc tttcaccaca ctaaaaattt atgaattagg acaagtgtcc
    21361 taacatcaac ttataaaagt aggcttttaa ccctatcaat aatgtggctt ttcaaccacg
    21421 cttcggcatt caaccctgcc tgtccgtagg cattttttac tcgggtttat atttgctaga
    21481 aaacatcatc tcattttcta agctttatta ctatatcatg tttttaagaa cttgtaaagt
    21541 attttttgat aaaaaacaaa aatatagtag attgaaacta gaatagtaca cctctgcttc
    21601 taaaacattg ttagaaatag attttactgt cctgatcgat ttgttctgtt cttgtttcat
    21661 tttactatat gttcgtaaat gaaagttcta taatgaagtt agccacccag ccctcctaaa
    21721 aattagatgg ttcaactagc tgatagctct tgtaggcata agaaaacacc tctgtgttat
    21781 acttgttgtt caaccacaaa cacaagaaag gcacagagat gcaagacaat tatactacaa
    21841 aagccaaaca tttgacaatc gatagccgtc gcttaatcga aagatggaaa aaagaaggaa
    21901 aatcaaatag agaaattgcc tctctacttg gaaaagctcc tcaaactatc cacactgaaa
    21961 tcaagcgtag gacagtccga caatgtcttg gaaaagggcg cttcaaagag gtttattctg
    22021 ccgactatgc tcaacagtct tatgaaaata atcgcaagca ctcggtcaag agatcaagcg
    22081 tgaccaagga actaaaggaa aagattctcc actatcataa ccaaaaattt tcgcctgaaa
    22141 tgatggtgat ggctaaaggg gttaacgtgg gaatttcaac catttactat tggattcatc
    22201 atggaaaatt ggggttaagc aagcaggatc tgctttaccc tagaaaagga aaagcgctta
    22261 agaaacaggc tagcaccaac tttaaacctg ctggtcaatc catcgaacag cggcctgaag
    22321 ctatcaatct tcgcttggag aatgggcatt atgagattga tacggttcta cttacgagat
    22381 cgaaaaacta ctgcttgctt gtcttgacgg atcgaaagag tagacatc
//
LOCUS       DBEJJV010000032        22311 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.032, whole genome shotgun sequence.
ACCESSION   DBEJJV010000032 DBEJJV010000000
VERSION     DBEJJV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22311
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.032"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            80..1683
                     /locus_tag="ACL3GT_001483"
                     /pseudo
     CDS             80..1683
                     /locus_tag="ACL3GT_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(1713..4265)
                     /locus_tag="ACL3GT_001484"
     CDS             complement(1713..4265)
                     /locus_tag="ACL3GT_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HGR0517136.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(4327..5949)
                     /locus_tag="ACL3GT_001485"
     CDS             complement(4327..5949)
                     /locus_tag="ACL3GT_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0517137.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            6155..7180
                     /gene="trpS"
                     /locus_tag="ACL3GT_001486"
     CDS             6155..7180
                     /gene="trpS"
                     /locus_tag="ACL3GT_001486"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HGR0517138.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            7332..8810
                     /gene="guaB"
                     /locus_tag="ACL3GT_001487"
     CDS             7332..8810
                     /gene="guaB"
                     /locus_tag="ACL3GT_001487"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HGR0517139.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(8861..9958)
                     /gene="recF"
                     /locus_tag="ACL3GT_001488"
     CDS             complement(8861..9958)
                     /gene="recF"
                     /locus_tag="ACL3GT_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HGR0517140.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(9961..10329)
                     /gene="yaaA"
                     /locus_tag="ACL3GT_001489"
     CDS             complement(9961..10329)
                     /gene="yaaA"
                     /locus_tag="ACL3GT_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HGR0517141.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            10488..11738
                     /locus_tag="ACL3GT_001490"
     CDS             10488..11738
                     /locus_tag="ACL3GT_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0517142.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYCSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            11735..13018
                     /locus_tag="ACL3GT_001491"
     CDS             11735..13018
                     /locus_tag="ACL3GT_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HGR0517143.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSIDTLVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLYLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            13060..13881
                     /gene="rodZ"
                     /locus_tag="ACL3GT_001492"
     CDS             13060..13881
                     /gene="rodZ"
                     /locus_tag="ACL3GT_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HGR0517144.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKISFLPLFYFIFFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            13892..14437
                     /gene="pgsA"
                     /locus_tag="ACL3GT_001493"
     CDS             13892..14437
                     /gene="pgsA"
                     /locus_tag="ACL3GT_001493"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HGR0517145.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            14434..15261
                     /locus_tag="ACL3GT_001494"
     CDS             14434..15261
                     /locus_tag="ACL3GT_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HGR0517146.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            15246..16085
                     /locus_tag="ACL3GT_001495"
     CDS             15246..16085
                     /locus_tag="ACL3GT_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HGR0517147.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            16078..16872
                     /locus_tag="ACL3GT_001496"
     CDS             16078..16872
                     /locus_tag="ACL3GT_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HGR0517148.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            16931..17749
                     /gene="mreC"
                     /locus_tag="ACL3GT_001497"
     CDS             16931..17749
                     /gene="mreC"
                     /locus_tag="ACL3GT_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HGR0517149.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            17749..18243
                     /gene="mreD"
                     /locus_tag="ACL3GT_001498"
     CDS             17749..18243
                     /gene="mreD"
                     /locus_tag="ACL3GT_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HGR0517150.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            18337..19515
                     /gene="pcsB"
                     /locus_tag="ACL3GT_001499"
     CDS             18337..19515
                     /gene="pcsB"
                     /locus_tag="ACL3GT_001499"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan hydrolase PcsB"
                     /protein_id="HGR0517151.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            19739..20518
                     /gene="rpsB"
                     /locus_tag="ACL3GT_001500"
     CDS             19739..20518
                     /gene="rpsB"
                     /locus_tag="ACL3GT_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HGR0517152.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            20597..21637
                     /gene="tsf"
                     /locus_tag="ACL3GT_001501"
     CDS             20597..21637
                     /gene="tsf"
                     /locus_tag="ACL3GT_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HGR0517153.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            21952..22206
                     /gene="tnpB"
                     /locus_tag="ACL3GT_001502"
     CDS             21952..22206
                     /gene="tnpB"
                     /locus_tag="ACL3GT_001502"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0517154.1"
                     /translation="MDSLAYVVKTHFELDSFSGQVFLFCGERKDRFKALYWDGQGFWL
                     LYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFSITPKI"
BASE COUNT         7130 a         3571 c         4581 g         7029 t
ORIGIN      
        1 agacaatatg tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa tttaaaaaaa
       61 accaaccttt attattgtca tgatcgggat ttctcttatt ccagatctgt acaatatcat
      121 atttttgtca tcaatgtggg attcatatgg gcaattgtct gacttacctg tggcagttgt
      181 aaataatgat aaagaggctt cctataatgg taatactatg gcaataggaa aagacatggt
      241 gtccaattta aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa
      301 gaagggattg gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctga
      361 aaaaacaact acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga
      421 gcaacaaact gagataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc
      481 tcagtcaatt gtagctttag tacaagattt acagggaagt ttagaaaact tacaaaatca
      541 atcttctaat ctttcgactt taaaaaatca atctaatcaa gtatcaccta ttacttctac
      601 ttctttgata ggattgtcaa gtggattaac agagatacaa ggagatgtta ctagcaaatt
      661 agttcctgcc agtcagtcga ttgcatcagg tgtaaacgca tatactacag gtgttgataa
      721 agtttctcag ggcgcaagtc aactaagtga aaaaaatgcc accttgacag gtagtttgga
      781 taaactagtt tcaggctcaa acaccttgac acaaaaatct tctagattga cagcaggagt
      841 tggttaatta caatcaggat ctgggcaatt agcagacaaa tccagtcagt tactttcagg
      901 tgcttctcca ttagagaata gagctaataa attggcagat ggatctggga aactagcaga
      961 aggtggaaca aagttaactt ctggattgga agatttacag acaggacttg cttctttagg
     1021 acaaggacta ggtaatgcta gtgatcaact caaatcagta tcaacagaat ctaaaaatgc
     1081 agagattttg tcaaatccac tcaatctttc aaaaacagac aatgatcaag ttcctgtaaa
     1141 tggaatcgca atagctcctt atatgatatc agttgctctt tttgttgcag caatatcaac
     1201 aaatatgata tttgcgaaat tgccttcagg acgtcatcca gagagccgtt gggcttggtt
     1261 gaaatcttga gctgaaataa atggtattat agctgttttg gcaggaattt tggtatatgg
     1321 aggagttcag cttattggtt taactgctaa tcatgagatg agaatattta ttctcatcat
     1381 cctaacaagt ttagtattca tgtctatggt gaccacttta gcaacgtgga atagccgtat
     1441 aggagctttt ttctcactta ttttgctttt actacagtta gcatcaagtg caggtactta
     1501 tccacttgct ttgacaaatg atttctttag atctattaat ccctggttac caatgagcta
     1561 ttcagtttcg ggattacgac aaacaatctc tatcaacaag tcattttcct agctgtcata
     1621 ctagttctat ttactagttt aggtatgcta gcctatcaac ataagaaaat ggaagaagat
     1681 taaaaaaatc gaccgattaa ctggtcgatt ttttatgcct tagatgactt tcgtctgtga
     1741 ttatagattc caaatagtaa gagagaagta aaggaacaga ttgctccagt aataaaacca
     1801 ttgggaatga aggaaagtgt aatagttcct ttccccttgg gaatgtcaac tttcataaat
     1861 ccagtttgag cttgtttaat ttctattttc ttaccatctt ggtaggcaga ccaacctttg
     1921 tcataaggaa tggtgaagaa aatagatgta tcttgttgga catcatatgt agcaaaaacc
     1981 ttgtttttag aagttgatac tgtgacaggt tgttctttaa ttttttgaat tgcctcggtg
     2041 aaagttttgg tatctaaacg atagaaggta ggagattcaa atgatacttg tgaatttcca
     2101 gggaaactaa cattgatatt gaaagttttt ttctctttag tatatcctag attaaagaag
     2161 gagaagacat tatcagttgt aaaagtcttt ttttcaccat ttacaaggat gtcaaccttc
     2221 ttttgtttat cgttagaaaa gtgaaggttt atgaaagaga gataaacttg gctgttttct
     2281 ggaacttcaa tttgatactg gattgctgca tcttcatttg aagaacttgt gacactaatc
     2341 aaatcattag tattttctat tttttctgtt ttttcataag gtattggaga aaaataatca
     2401 aaattgacgt tagcaagttg atttaaaaat gaggcctgat tatccaaggt atgttcattg
     2461 aacttgacat cattgtaaac agattgacta gcaactgcaa tcggaagaga gtattgattt
     2521 tcatataggg taagattatc tttttgatag atatctttaa agccatactt atcaatagga
     2581 ctgtctgaga tattgtactg gataccaaat aaactatcag ccaaaatact attatttgca
     2641 tatcggagat tgagattagt cccagaggat ttaaaaccaa gtttatctaa agtagagctt
     2701 gatgaacgat ttcgaacaga tgaaaattga gagattccat tgtagttgaa tttcatactg
     2761 tcatttcctg tctgagtttg tagtttttca gtacgagtaa attgatttcc aatatatgtt
     2821 gagaaagatt ccatagctgg gatatctcga ctataagcac ttcgagaagc aaatccccat
     2881 tccttagcaa ttccgtccat ttgagatgaa gcatttaaac tcatttcaac cagtataaat
     2941 aaagagatta gaatggcaaa tagattcaca gatataaact ttttgataac tgcaaggagt
     3001 aaaagagaat agacaaccaa aaattcaaga gtaagcagaa tattcaaatc tgttaaaaaa
     3061 gaataatgcg attttagata gatggtagct aaaaatcctg ttactacaag aaaaagcgaa
     3121 actaaaaaat tccagacttt aagttctttc agacgcttta agacttctgc tgctgtgtaa
     3181 attaacaagg tagagaaaat ccaagcatag cgatgtaaaa acatgtttgg agtatgcatg
     3241 ccttgccaaa ataagtcaag agcttctatg taaaagcttg caattagaaa tgcaaagaat
     3301 attacatata tgagtttcac gtgaaactta atagatttca gcgtaaaaaa taaaatggtc
     3361 aaaataaagg gaaatagtcc aacaaaaatc attgggatgg ccccatactt tgttgtgtca
     3421 aaggaaccaa tgaattgctt agcaaagaga tcaagatacc agctactttc agtttgaaac
     3481 tttgtaactt cagtcaattt ttccccatgt gtctgtaaat caaatagagt gggaagagtc
     3541 ataatcaaac tagccatacc agctaaaaag gagataacta tgaaatcaag aacagatgat
     3601 tttcgagtct taaagtccca cgaaatttga cagagatacc agaaaataag aaacaatact
     3661 gtcatatatc caaaataata attttgaata aataagattg acagacttgt aaagtacaat
     3721 aggagtttct tttcagttat cagtagatgt aaaccagtta taattaaagg aatcaagata
     3781 aaaacatcta gccaggtttt tatctctaat tgactgacag tgaaactcat cagagcatag
     3841 gaagtagata aggctagttt taaagtctga gggatagatt gaaacaattt attcaaacta
     3901 aaaaaggttg acagaccaat caatccaaat tttaagagag tggtcagata gacagcatct
     3961 ggcatattcg ttagatcaaa aaagtaaact agaggcgcga gaaaactacc caagtaataa
     4021 ctagataggg catagaagtt tagccctaga ccacttgtaa aggtgtaaaa cagactacta
     4081 tttccatgta ggatatttcg taaggctaca tcaaaaataa cgtattgatg aaagccatct
     4141 cctaatagag gagagttgtc gctattccag tagatacctt gagatagata tactccagac
     4201 ataatcacta caggaatgat gaaagaaata aaataggttc gatatgtttt taaaaatgat
     4261 ttcatgttac ctcgtagaat gatagaaaac tcagttggtt aacccaactg agttttgaag
     4321 ttttatttag tctttccaaa gttctttaac ttttgcttgt acttctgcat tttctaggaa
     4381 ttcatcgtag gtttcatcga tacggtcaat gacgccattt ttagataaga caatgatatg
     4441 gttagccaaa gtttgaataa actcgtggtc atggctggca aagatgattg attctttaaa
     4501 gtttttcaat ccatcattca agcttgagat agattccaag tccaagtgat ttgttggatc
     4561 atcaagtaca aggacatttg attttaagag catgagtttt gaaagcatga cacgaacttt
     4621 ttctccccct gacaagacat ttacaggttt gttaacttca tctccagaga agagcatacg
     4681 gccgaggaaa ccacgtagga aagtattgtc atcatcttct ttacttgcga attgacgcaa
     4741 ccagtcaaga attgattctc ctcctgcaaa atcagctgag ttatcttttg gtaggtaaga
     4801 ttgactagtt gtaactcccc acttgacagt tccttcatag tcaatatctc ccatgattgc
     4861 acgaattaat gcagtcgttt gaatatcatt ttgtccaata agtgctgtct tatcatctgg
     4921 acgcaagatg aaactaatat tatccaagat agtttcacca tcaatcttta cagttagatt
     4981 ttctactgtc aagagatcat taccaatctc acgttccgct ttaaagttga taaatggata
     5041 tttacgacta gatggtacaa tctcttctag ctcaatctta tcaagcattt tcttacgtga
     5101 tgttgcctgc cttgacttag aagcattggc agagaaacga gcaacgaatt cttgcaattg
     5161 tttaattttt tcttctgctt tagcattacg gtctgctagc aatttagcag caagctcaga
     5221 agattccttc cagaagtcgt agtttccgac atagagtttg atttttccaa agtcaaggtc
     5281 ggccatgtga gtacaaactt tgtttaagaa gtgacggtcg tgggatacta cgataactgt
     5341 gttatcaaag tcaattaaga agtcttctaa ccaagtaatc gattggatat ccaaaccgtt
     5401 agtaggctcg tccaagagaa gaacatctgg tttaccaaaa agtgctttgg cgaggagaac
     5461 ctttactttt tcaccgttgg ccaattcgct catgttttgg tagtgtaatt cttctggaat
     5521 gtttaggttt tgaagtagtt gagaggcttc actctctgct tcccaacctc caagttcggc
     5581 aaactctcct tcgagttcgg cagcacgaac cccgtcctcg tctgagaaat cttccttcat
     5641 gtagatagca tctttctctt tcatgatgct ataaagtttt tcatttccca tgataacgac
     5701 atcaatggca cgttcatctt cgtagtcaaa gtgattttga cgaagaacag agagacgttc
     5761 atctggacca agagagatgt gaccagtagt aggttcgata tctccagcta aaatttttaa
     5821 aaaggttgat tttccggcac cattagcacc gattaatccg taagtatttc cttctgtaaa
     5881 tttgatattg acatcatcaa aaagtttgcg atcactaaaa cgtagtgaaa catcagatac
     5941 tgtaagcaat atttttctcc tatatgtgta atatatttat tctactagaa aatacagaaa
     6001 tattcaaatt tttatttttc aattttgtgt aaattatatt tacagtatcc tttacacaaa
     6061 tctgtaaaaa gcaaggctga tttattttga taaattacgg ttatttcatt aaaaaaatgc
     6121 tataattgaa aggactatat cgaaggagaa caaaatgact aaacccatta ttttaacagg
     6181 agaccgtcca acaggaaaat tgcatattgg acattatgtt ggaagtctca aaaatcgagt
     6241 attattacag gaagaggata agtatgatat gtttgtgttc ttggctgacc aacaagcctt
     6301 gacagatcat gccaaagatc ctcaaaccat tgtagagtct atcggaaatg tggctttgga
     6361 ttatcttgca gttggattgg atccaaataa gtcaactatt tttattcaaa gccagattcc
     6421 agagttggct gagttgtcta tgtattatat gaatctagtt tcgttagcac gtttggagcg
     6481 aaatccaaca gtcaagacag agatttctca gaaaggattt ggagaaagca ttccgacagg
     6541 attcttggtc tatccaatcg ctcaagcagc tgatatcaca gctttcaagg ctaattatgt
     6601 tcctgttggg acagatcaga aaccaatgat tgagcaaact cgtgaaattg ttcgttcttt
     6661 taacaatgca tataactgtg atgtcttggt agagccggaa ggtatttatc cagaaaatga
     6721 gagagcaggg cgtttgcctg gtttagatgg aaatgctaaa atgtctaaat cactaaataa
     6781 tggtatttat ttagctgatg atgcggatac tttgcgtaaa aaagtaatga gtatgtatac
     6841 agatccagat catatccgcg ttgaggatcc aggtaagatt gagggaaata tggttttcca
     6901 ttatctagat gtttttggtc gtccagaaga tgctcaagaa attgctgata tgaaagaacg
     6961 ttatcaacga ggtggtcttg gtgatgtgaa gaccaagcgt tatctacttg aaatattaga
     7021 acgtgaactg ggtcctattc gtgagcgccg tattgaattt gctaaggata tgggagaagt
     7081 ttataatatg attcaaaaag gtagtgaaag agcgcgtgaa gttgcgggtc aaaccctatc
     7141 tgaggtaaaa ggggcaatgg gacttcatta ctttaactaa gtttatttta caagaaacta
     7201 tcttttctat ctcgaagaaa agatagtttt ttatttaccc ctgtaacatt tgacaaattt
     7261 ttatagaatg gtatgataga tacaatataa aaagagtcaa gctcaaaaag aaagaaaaga
     7321 ggaaacttcg aatgtctaat tgggacacta aatttttgaa aaaaggtttt accttcgatg
     7381 atgtattgct tattccagct gaaagtcatg tgttgcctaa cgatgcagat ttaacaacta
     7441 aattggcaga taatttgact ttaaatatcc caattattac cgctgccatg gacacagtta
     7501 cagagagtca aatggccatt gctattgctc gtgcaggcgg tctcggagtt atccataaaa
     7561 acatgtcaat tgctcaacaa gcagacgagg ttcgtaaggt aaaacgttct gaaaatggag
     7621 ttattattga tccgttcttc ttgacgcctg aacatacaat tgctgaagca gatgagctta
     7681 tgggtcgtta ccgcatcagt ggtgttccag ttgttgaaac acttgaaaat cgtaaattgg
     7741 ttggtatttt gacaaaccga gatcttcgtt ttatttcaga ttataatcaa ccaatttcaa
     7801 accatatgac tagtgaaaat cttgttactg ctcctgtggg tacggatctt gcaacggctg
     7861 agagtattct tcaagagcat cgtattgaaa aacttccgtt ggtcgatgaa gaaggcagtc
     7921 tttctggttt gatcactatc aaagatattg aaaaagttat tgagtttcca aatgcggcta
     7981 aagatgagtt tggtcgtctt ctagttgcag gtgcagtagg tgttacttca gatacatttg
     8041 aacgtgcaga ggctcttttt gaggcaggag cggatgcgat tgttattgat actgcacatg
     8101 gtcattctgc aggtgtcttg cgtaaaattg ccgagattcg tgctcatttc ccagatcgga
     8161 ctttgattgc tggaaatatt gctactgctg aaggtgcacg tgccctttat gaagcgggtg
     8221 tagacgttgt taaggttggt attggaccag gttctatctg tactactcgt gtgattgctg
     8281 gtgttggtgt tccgcaagta acagctatct acgatgctgc agctgttgcg cgcgaatatg
     8341 gtaaaacgat tattgctgac ggtgggatca agtattctgg agatattgta aaagcacttg
     8401 ctgcaggtgg aaatgctgtt atgcttggat ctatgtttgc tggaactgat gaagctccag
     8461 gcgaaactga aatcttccaa ggacgtaaat tcaagactta ccgtggtatg ggatcaattg
     8521 ctgctatgaa gaaaggttca agcgaccgtt atttccaagg ttctgtcaat gaagcaaaca
     8581 agcttgttcc agaaggaatt gaaggtcgtg ttgcttataa aggagcggca gctgatattg
     8641 ttttccaaat gattggtggt attcgctctg gtatgggtta ctgtggtgca gctaacctta
     8701 aagaactaca cgataatgct caatttattg aaatgtctgg tgctggtttg aaagaaagcc
     8761 atcctcatga tgtgcaaatt actaatgagg caccaaatta ttctatgtaa aaaacaatga
     8821 aaagaactcc agtgaaaaca ggagttcttt tacaatgttg tcaatttcca tttacagaag
     8881 ctttaccatc ctgaatagtg aagatactta gattttctgg cagattttga agatggtcta
     8941 agcttgttgt tgtgataaag gtttggattg attgagaaat cgtttctaat aattttaact
     9001 gtctagtgtt gtcaagttca ctcatcacat cgtcaagcag taatatcgga gattctgtgg
     9061 taatgctttc cattaattcg atttctgcta attttatcga gaggacgaga ctacgatgtt
     9121 gaccttggct tccgaaacta gcatccatcc catttatata aaaagaaatg tcatctcgat
     9181 gaggaccgac accagtattc tttttaaata aatctctgga tctacttttt tctaaagcaa
     9241 ttttgaaaga ttcggataag ttttgtttgt cagttatatt gacagaagat tgataggata
     9301 ttgacaactc ttcgatctga ttagagagtt caaaatgttt cttacgccca aatgattcta
     9361 gtttttttat gaaatctaag cggtgattca ttacacgaca tccataatca actagctgat
     9421 catctaacac agaaaggaat gtttcatcta ttttttgatc tgattttagg taagtgtttc
     9481 tttgctttag gatgtggtta taattggtta agtcagataa gtagattggc ttaatttgcc
     9541 caagttccat atcaatgaat tttcgtcgaa tcgaaggtgc tcctttaatt agttgtaaat
     9601 cttcaggagc aaataagaca acattcatgt gtcctacata atctgaaagg cgtgcctgtt
     9661 ttaagtgatt aacttttgtt acacggcctt tttgtgttag ttcgatttct aggggaatgg
     9721 atccagtttt tttctgaacg agacctgaaa gatgaagttg ttcctcatca aaatgaatga
     9781 gatttttatc tgttcgagtt cgatgactac gcgttaaggc taaaaaatag atagcctcta
     9841 acatgtttgt ttttccttgt gcattacgtc ccaaaaagac attcaattta ggattaaagt
     9901 ctattttcgt ttctttgtaa ttacgaaaag tcttgagaga tagatgttgt agccacatga
     9961 ttatctacca gggaatcgtg gagcttgttg gcttttaggt gatgaagcag gtttcgattt
    10021 gtctttttta actcccttat tcatcttttt gacaagttta gcgatccgtt ctttttcaac
    10081 tttatcagct tggtattcat cttgttcttc agaagtaggt tgtgtcaaca agatgtcaat
    10141 gttcatgtca gggatgtcaa ctttatcgcc aatacgaagt ttttttccac gacgactctc
    10201 taattcccta ttaaagtaaa cagaatgttc agagagaaat gatttaatag ctcctccgct
    10261 atgtgtaatt ccaagttctt tgagtagtgc ttggagggta ataaattctt caaataattt
    10321 gtattccata attcacctca atctttggta ttataccata ttttcctaaa aatagtgaga
    10381 gagacagcga gaaatgtaag cgatttttat ttcaaaagtg ttacagggaa caagaaaatt
    10441 tcaggttttc gtgatataat agaagtctgt atataaggag gtaaatcatg gagttagtgc
    10501 atggaatttc aacacatttt atccaatcaa aaaagtttaa aacaaacaaa attaccgtgc
    10561 gttttaccgc tccattatcc cttgatacga ttgcaggtca catgttgagt gcaagtatgc
    10621 tagagactgc taatcagatg taccccactt ctcaagattt gaggagacac ttggccagtc
    10681 tatacggtac agatatgtca accaattgtt tcagaagagg gcaaagccac attatagaat
    10741 tgacatttac ctatgttcgt gatgagtttt taagtaggaa aaacgtgcta acctctcaga
    10801 ttttggaact tgtaaaagaa actctttttt cacccgtagt agttgataat gggtttgatc
    10861 cggccttatt tgaaattgag aaaaaacaat tgctagcaag tttagcagct gatatggatg
    10921 attcttttta ttttgcacat aaagaattgg ataaattgtt ttttcatgat gaacgtcttc
    10981 aattggaata tagtgattta cgaaatcgta ttttagctga aactccacaa agttcttatt
    11041 cttgtttcca agaattttta gccaatgatc gaatagattt ctttttccta ggtgatttta
    11101 atgaggttga aattcaaaat gtattagaat catttggctt taaaggtcga aaaggagatg
    11161 tgaaggttca gtattgtcaa ccttattcta atatccttca ggaaggtatg gttcggaaaa
    11221 atgtgggaca atccattttg gaattaggtt atcattactg ttctaaatat ggtgatgagc
    11281 aacatttacc catgattgta atgaatggtt tacttggtgg atttgctcac tctaagctct
    11341 ttacaaatgt ccgtgaaaat gctggattag cttataccat ttcaagtgag cttgatttat
    11401 ttagtggatt cttgaggatg tatgctggta tcaatcgaga aaatcgtaac caggctcgta
    11461 aaatgatgaa taatcaactg cttgatttaa aaaaaggtta ttttacagag tttgagttaa
    11521 atcagaccaa ggaaatgatt cgttggtcgt tgttactttc tcaagataat caatcttcat
    11581 tgattgaacg tgcttatcaa aatgccttat ttggaaaatc ttcagcagac tttaaaagtt
    11641 ggattgcaaa gcttgaacag attgacaaag atgctatttg tagagtagct aataatgtga
    11701 aactacaagc gatttacttt atggaaggaa tagaatgaca aaggttgttt ttgaagaaaa
    11761 atactatcca gctgtaaaag aaaaggttta tcgaactcgt ttggccaacg gattgacagt
    11821 tgctcttttg cctaaaaagg aatttaaaga ggtttacggg agtgtaactg tacagtttgg
    11881 ttcgatagat acgcttgtca cagaagttga cggagatgta aaacaatatc ctggaggaat
    11941 tgctcatttt cttgaacata aattatttga gagagaagat tctagtgatt tgatgtcggc
    12001 ttttacgagt ctaggtgcag atagtaatgc ctttacaagc tttacaaaaa caaactatct
    12061 tttttcagca acggattatt ttttagaaaa tttatattta cttgatgaat tggtaacatc
    12121 agcacacttt actgaagctt ccattctgac agagcaggat attattcagc aagaacgaga
    12181 aatgtaccaa gatgatccag attcgtgttt attcttttca actttagcga atttgtatcc
    12241 tggtacacct ttagcaactg atatagttgg aagtgaggag tccatttccc aaatcaatct
    12301 aactaatttg caagaaaatt ttacaaagtt ttacaaacct gtaaacatgt ctctgttttt
    12361 agttggtaat tttgatgtgg agcgagtaca ggactatttt gaaagcaaag aactgaaaga
    12421 ttcagatttt caggaagtag caagagaaaa gttgttttta cagcctgtaa agccaacaga
    12481 tagtatgaga atggaagtat cttctcccaa actagcgatt ggagttagag gtaagcgaga
    12541 agtttctgaa gcggattgct atcgacatca tattttatta aaattattgt ttgcaatgat
    12601 gtttggttgg acttcggatc gttttcaaaa atgttatgaa tcaggtaaaa ttgatgcgtc
    12661 cttatctctg gaagttgaaa taacaagtcg ctttcatttt gtcatgttga caatggatac
    12721 gaaagagcca gttgctttgt ctcatcaatt taggaaggct attcgtaatt ttacaaagga
    12781 tttagatatt acagaggaac atttagatat tatcaaaaga gagatgtttg gcgaattttt
    12841 cagtagcatg aactctcttg aatttattgc aacgcaatat gatgcttttg aaaatggtga
    12901 gacaattttt gatttgccga aaattttaca ggaaattact ttagaggatg tccttgatgc
    12961 tggacatcat ttaatagatg atggtgacat agttgatttt acaatattcc catcgtagta
    13021 acctattata atagacacta gaaagaaggg atgacaagta tgagaaaaaa aacaattgga
    13081 gaggttttac gattagctag aatcaatcag ggattgagtt tagatgaatt gcagaaaaag
    13141 acagaaatcc agttagatat gttggaagca atggaagcag acgatttcga tcaacttcca
    13201 agtccttttt acacgcgttc tttcttgaaa aaatatgcat gggctgttga gttagatgac
    13261 caaattgttt tggatgctta tgattctggg agtatgatta cttatgagga agtagatgtt
    13321 gatgaagatg agttgacagg tcgtagacgt tcaagtaaga aaaagaagaa aaaaatatca
    13381 tttttacctt tattttattt tatctttttt gctttatcga ttttaatttt tgtgacttat
    13441 tatgtttgga actatattca aactcaacca gaggagcctt ctctttctaa ttacagtgtg
    13501 gttcaatcaa caagttcaac tagctctgtt ccccactcct caagtagtag ttcttctagt
    13561 atagaatcag ctataagtgt atcaggcgaa ggaaatcatg tagaaatcgc ttataagaca
    13621 agtaaggaaa cagttaaatt gcaattggca gtttcagatg ttacaagttg ggtcagtgtt
    13681 tcagaaagcg aacttgaggg cggtgtaacc ttatcgccaa agaagaaaag tgcagaagca
    13741 acagttgcaa ctaaaagtcc tgtaacaatt acgttaggtg ttgtaaaagg tgttgatttg
    13801 acagtagata atcagactgt tgatttatcg aaattaacag ctcagactgg acaaatcact
    13861 gtaaccttta ctaaaaatta aggaaaaacg aatgaaaaaa gaacaaattc ccaatctctt
    13921 aacaataggt cgaattctct ttatacctat ttttatcttt attttaacga taggaaattc
    13981 gatagagagt catatagttg cagctattat ctttgctgtt gccagtatta ccgactattt
    14041 agatggatat ttagctcgta aatggaatgt ggtcagtaat tttggtaaat ttgcagatcc
    14101 tatggcggat aagttactag ttatgtcggc ttttattatg ttgattgagt taggtatggc
    14161 tccggcttgg attgttgcag tgattatctg tcgtgagtta gctgtgacag gtttaaggct
    14221 tttattggtt gaaactggtg gaacaatttt agcagcagca atgcctggaa aaattaaaac
    14281 ttttagtcag atgtttgcca ttattttctt gctattacat tggactttgc ttggtcaagt
    14341 tctactttat gtagccttat ttttcactat ctactctggc tatgactatt tcaagggtag
    14401 tgcctatgta tttaaaggga catttggttc gaaatgaaat caataattga tgtaaaaaat
    14461 ctttcttttc gctataaaga aaatcagaac tactacgatg tgaaggatat tacgtttcac
    14521 gtgaaacgtg gagaatggct ttcgattgta gggcataatg gtagtggtaa atcaacgacg
    14581 gttcgattaa ttgatggctt actggaagca gaatccggag agattgtaat tgatggccaa
    14641 cgtttgactg aggaaaatgt ttggaatata cgtcgtcaaa tcggtatggt ttttcaaaat
    14701 ccagacaatc aatttgttgg agcgactgtt gaagatgatg ttgcttttgg tttggaaaat
    14761 cagggacttt ctcgtcaaga aatgaaaaag agagtggaag aagctctggc tttagttggc
    14821 atgttggact ttaaaaagag agagccagcg cgtctatcag gtggccaaaa gcaacgtgtg
    14881 gccattgcag gtgttgtagc cctaagacca gctattttaa tcttagatga agcaacgagt
    14941 atgttggatc ctgaggggcg tagagaactt attgggacag taaaaggaat tcgaaaagac
    15001 tatgatatga cggtcatttc tattacccat gatttggaag aagtcgccat gagtgatcgc
    15061 gtattggtca tgaaaaaagg ggaaattgaa tcaactagta gtccaaggga gcttttctct
    15121 cgaaatgatt tagatcaaat tggattagac gatccttttg ctaatcaatt aaaaaaatct
    15181 ttgagccaga atggctatga tttacctgaa aattatttga cagaaagtga gctagaggat
    15241 aagctatggg aattgctcta gaaaatgtga attttacata tcaagaaggt actcccttag
    15301 cttcagcagc tttgtcggat gtttctttga cgattgaaga tggctcttat acagctttaa
    15361 ttgggcacac aggtagtggt aaatcaacta ttttacaact cttaaatggt ttattggtgc
    15421 caagtcaagg gagtgtgagg gtttttgata ccttaatcac ctcgacttct aaaaataaag
    15481 atattcgtca aattagaaaa caggttggct tggtatttca gtttgctgaa aatcagattt
    15541 ttgaagaaac ggttttgaag gacgttgctt ttggaccgca aaattttgga gtttctgaag
    15601 aagatgctgt gaagactgcg cgtgagaaac tggctctggt tggaattgat gaatcacttt
    15661 ttgatcgtag tccgtttgag ctgtcagggg gacaaatgag acgtgttgcc attgcaggca
    15721 tacttgccat ggagccagct atattagtct tagatgagcc aacagctggt ctagatcctc
    15781 tagggagaaa agagttgatg accctgttca aaaaactcca ccagtcaggg atgaccatcg
    15841 tcttggtaac gcatttgatg gatgatgttg ctgaatatgc gaatcaagtc tatgtaatgg
    15901 aaaagggacg tttagtaaag gggggcaaac caagtgatgt ctttcaagac gttgttttta
    15961 tggaagaagt tcagttggga gtacctaaaa ttacggcctt ttgtaaacga ttggctgata
    16021 gaggcgtgtc atttaaacga ttaccgatta agatagagga gttcaaggag tcgctaaatg
    16081 gatagtatga ttttagggcg ttatatccca ggggattcga ttgttcaccg attggatcca
    16141 cgtagcaaat tgcttgctat gatgctactg attttgattg tgttttgggc taataacccc
    16201 ttgacgaatc tgattctttt tatagcgaca gggatattta ttgccttgtc aggagtatct
    16261 ctttcatttt ttattcaggg cttgaagtct atgtttttct tgattgcctt cacaactatt
    16321 tttcaactat ttttcatttc taatgggaat gttttatttg agttttcgtt tgtgagaatc
    16381 acggattatg ctttgcaaca agctgggatt attttttgtc gctttgtatt gattattttc
    16441 ttttcaactt tgttaacctt aacaaccatg cctttaagtt tggcatcagc tgtcgaagct
    16501 ttattagcac ctttaaagcg tgtgaaagtt ccagttcatg aaattggatt gatgctgtct
    16561 atgagtttgc gttttgtccc aaccttgatg gatgatacga ctcggattat gaatgcacag
    16621 aaagctcgtg gagtggattt tggagaagga agcatcgttc aaaaagtaaa ggcgatgatt
    16681 cccattttga ttcctctttt tgcgacaagt ttaaaacgtg cagattcctt ggctatcgct
    16741 atggaagcgc gtggctatca gggtggaaaa ggcagaagtc aataccgaca attgaaatgg
    16801 actctgaagg atacgctgac cattcttgtt attctcgtac ttggttgttg tttatttttc
    16861 ttaaaatctt agtagctttc aggaattgat aaaaagttac tgtaacagtt tttgatataa
    16921 aggtaggaat atgaaccgtt ttaaaaaatc aaaatatgtc attattgttt ttgtcactgt
    16981 tctgcttgtg tcagctctct tagcgacgac ttattcaagt acaattgtga caaaattagg
    17041 agatggaatc tcattggttg atagagttgt acaaaaacct tttcagtggt ttgattctgt
    17101 caaatcagat ttggctcatt tgacacgaac atataatgaa aatgaaagtt tgaagaaaca
    17161 gctttaccaa ttagaagtta aatcaaatga ggtggaaagt ttaaagacag aaaatgaaca
    17221 actgcgccaa ttgcttgata tgaagtctaa attgcaagcc acaaagactt tagcagcaga
    17281 tgttattatg cgttctccgg tatcttggaa gcaggagttg accttagatg caggtagatc
    17341 aaaaggtgct tctgagaaca tgttagctat tgcaaatggt ggcttgattg ggagtgtttc
    17401 aaaagtagag gagaactcta ctatagtcaa ccttctgaca aatacggaaa atgctgataa
    17461 gatttctgtt aaaattcaac atggctctac tacaatttat ggaattatta ttggctatga
    17521 caaggaaaat gacgttctta aaattagcca attaaatagt aatagcgata ttagtgcggg
    17581 agataaggtg actactggtg gattaggaaa ctttaacgtt gctgatattc ctgttggtga
    17641 agtggttgcc acaacgcata gtacagacta tttgacacga gaagtaactg ttaaattgag
    17701 tgcagatact cataatgtag atgtgataga attagtgggg aattcataat gagacagttg
    17761 aagcgagttg gagtattttt attgcttcct ttctttgttc taattgacgc ccatattagc
    17821 cagcttctgg gctcattttt cccccatgta catttggcta gtcattttct ttttctattt
    17881 ctcttatttg agacgataga agtatcagag tatctctacc tagtctattg ttttgttata
    17941 ggcttggttt atgatgttta ctttttccat ctaataggga ttacaactct cttatttatc
    18001 ttattgggag ccttccttca taaattgaat agtgttattt tgttgaatcg ttggacaaga
    18061 atgctagcta tgattgtgct gacattcctg tttgaaatgg gtagttatct tttggctttt
    18121 atggtagggt tgacagtaga tagcatgtcg atttttatag tctatagctt ggtaccgacg
    18181 atgattttaa attttttatg gattactgtt tttcaattta tttttgaaaa atattatcta
    18241 taagaacgac atataaatgt aacaaaggcg taatatttat taggcctttt tttggtatac
    18301 tagtattgtc tttaaaagaa ggagtatcta cgtaatatga agaaaaaaat cttagcgtca
    18361 cttttattaa gtacagtaat ggtttctcaa gtagctgttt taacaactgc gcatgcagaa
    18421 acgactgatg acaaaattgc tgctcaagat aataaaatta gtaacttaac agcacaacaa
    18481 caagaagccc aaaaacaagt tgaccaaatt caggagcaag tatcagctat tcaagctgag
    18541 cagtctaact tgcaagctga aaatgataga ttacaagcag aatctaagaa actcgagggt
    18601 gagattacag aactttctaa aaacattgtt tctcgtaacc aatcgttgga aaaacaagct
    18661 cgtagtgctc aaacaaatgg agccgtaact agctatatca ataccattgt aaactcaaaa
    18721 tcaattacag aagctatttc acgtgttgct gcaatgagtg aaatcgtatc tgcaaacaac
    18781 aaaatgttag aacaacaaaa ggcagataaa aaagctattt ctgaaaaaca agtagcaaat
    18841 aatgatgcta tcaatactgt aattgctaat caacaaaaat tggctgatga tgctcaagca
    18901 ttgactacga aacaggcaga actaaaagct gctgaattaa gtcttgctgc tgagaaagcg
    18961 acagctgaag gggaaaaagc aagtctatta gagcaaaaag cagcagctga ggcagaggct
    19021 cgtgcagctg cggtagcaga agcagcttat aaagaaaaac gagctagcca acaacaatca
    19081 gtacttgctt cagcaaacac taacttaaca gctcaagtgc aagcagtatc tgaatctgca
    19141 gcagcacctg tccgtgcaaa agttcgtcca acatacagta caaacgcttc aagttatcca
    19201 attggagaat gtacatgggg agtaaaaaca ttggcacctt gggctggaga ctactggggt
    19261 aatggagcac agtgggctac aagtgcagca gcagcaggtt tccgtacagg ttcaacacct
    19321 caagttggag caattgcatg ttggaatgat ggtggatatg gtcacgtagc ggttgttaca
    19381 gctgttgaat caacaacacg tatccaagta tcagaatcaa attatgcagg taatcgtaca
    19441 attggaaatc accgtggatg gttcaatcca acaacaactt ctgaaggttt tgttacatat
    19501 atttatgcag attaatttac agagggactc gaatagagcc ctcttttcag gttttaccgt
    19561 gacaatccct attaaaaatt atatcaaaat agcttgaaaa tattggaaaa gtatggtaga
    19621 atgaaaattg tcgtgtgaac gataatactc attcttgatg aattgtgaag cagttgccct
    19681 tgggtcgttt tgcgagttga agtcaagaag aggaaaaaaa caaaaaggag aaatactcat
    19741 ggcagtaatt tcaatgaaac aacttcttga ggctggtgta cactttggtc accaaactcg
    19801 tcgctggaat cctaagatgg ctaagtacat ctttactgaa cgtaacggaa tccacgttat
    19861 cgacttgcaa caaactgtaa aatacgctga ccaagcatac gacttcatgc gtgatgcagc
    19921 agctaacgat gcagttgtat tgttcgttgg tactaagaaa caagcagctg atgcagttgc
    19981 tgaagaagca gtacgttcag gtcaatactt catcaaccac cgttggttgg gtggaactct
    20041 tacaaactgg ggaacaatcc aaaaacgtat cgctcgtttg aaagaaatta aacgtatgga
    20101 agaagatgga actttcgaag ttcttcctaa gaaagaagtt gcacttctta acaaacaacg
    20161 tgcgcgtctt gaaaaattct tgggcggtat cgaagatatg cctcgtatcc cagatgtgat
    20221 gtacgtagtt gacccacata aagagcaaat cgctgttaaa gaagctaaaa aattgggaat
    20281 cccagttgta gcgatggttg acaccaatac tgatccagat gatatcgatg taatcatccc
    20341 agctaacgat gacgctatcc gtgctgttaa attgatcaca gctaaattgg ctgacgctat
    20401 tatcgaagga cgtcaaggtg aggatgcagt agcagttgaa gcagaatttg cagcttcaga
    20461 aactcaagca gattcaattg aagaaatcgt tgaagttgta gaaggcgaca acgcttaatt
    20521 tatacaaata gtaattacct aggagggcgg ggcttagccc ggctctccta ttttcaaaaa
    20581 atataggaga attaaaatgg cagaaattac agctaaactt gtaaaagagt tgcgtgaaaa
    20641 atctggtgcc ggtgttatgg acgctaaaaa agcgcttgta gaaacagacg gtgacatcga
    20701 aaaagcgatt gaattgcttc gtgaaaaagg tatggctaag gcagctaaga aagctgaccg
    20761 tgttgctgca gaaggtttga ctggtgttta tgttaacggt aatgttgcag cagttattga
    20821 agtaaacgct gaaactgact tcgttgcaaa aaacgctcaa ttcgttgaat tggtaaatac
    20881 tacagctaaa gtcattgctg aaggaaaacc tgctaacaac gaagaagctc ttgctttgat
    20941 aatgccttca ggtgaaactc ttgaagctgc atacgtatct gcaacagcaa ctatcggaga
    21001 gaaaatctca ttccgtcgct ttgcattgat tgaaaaaaca gacgcacaac actttggagc
    21061 ataccaacat aacggtggac gtatcggtgt tatttcagtt gttgaaggtg gagacgaagc
    21121 acttgctaaa caattgtcaa tgcacatcgc agcgatgaaa ccaacagttc tttcttacaa
    21181 agaattggat gagcaattcg ttaaagatga gttggcacaa ttgaatcacg ttatcgacca
    21241 agacaacgaa agccgtgcaa tggttaataa accagctctt ccacacttga agtatggatc
    21301 aaaagctcaa ttaactgatg atgttattgc tcaagctgaa gctgacatca aagctgaatt
    21361 ggctgcagaa ggtaaaccag aaaaaatctg ggacaaaatt attccaggta aaatggatcg
    21421 cttcatgctt gataacacta aagttgacca agcttacaca cttcttgcac aagtttacat
    21481 catggatgac agcaagacag ttgaagcata ccttgaatca gttaacgctt cggtagttga
    21541 gtttgctcgc tttgaagttg gtgaaggtat cgagaaagct gcaaacgact tcgaagctga
    21601 agttgcagct acaatggcag cagccttgaa taactaataa tagaaaggaa gcaaattgct
    21661 tccttttttg tatagggctt agatttttcc tgaaattgtt ttttccccag cctcactcga
    21721 ttagaataat taaaacaaaa agccctataa taagggctaa gtgcatttag gagactatac
    21781 ttcaaattca tagtaagcgc gtcataacaa ggtatctatc ctaattcccc aacttccagt
    21841 atactagata aaaaataatt atcggaggaa aggtattgta ctatgataat tcaactaagt
    21901 gatttaggtc aagttcacct tgtttgtgac aagacagata tgaggtaggg aatagactca
    21961 ttagcctatg tagttaaaac ccactttgaa ttggattctt tctccggtca agtctttctc
    22021 ttttgtggtg aacgtaaaga ccgctttaaa gccctttact gggatggtca aggattttgg
    22081 ctactatata aacgctttga gaacggaaaa ctgacttggc taagtacaga aaaggatgtc
    22141 aaagctctcg cacctgaaca agtagattgg cttatgaagg gcttttctat cactccaaaa
    22201 atatagtaga ttgaaactag aatagtacac ctctgcttct aaaacattgt tagaaatcga
    22261 tttgattgtc ctgatcgatt tgtcctgttc ttatttcatt ttactataaa t
//
LOCUS       DBEJJV010000033        22094 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.033, whole genome shotgun sequence.
ACCESSION   DBEJJV010000033 DBEJJV010000000
VERSION     DBEJJV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 22094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.033"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..267
                     /gene="comGC"
                     /locus_tag="ACL3GT_001503"
     CDS             <1..267
                     /gene="comGC"
                     /locus_tag="ACL3GT_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HGR0517155.1"
                     /translation="MLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAEL
                     YSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGANRKVND"
     gene            260..664
                     /gene="comGD"
                     /locus_tag="ACL3GT_001504"
     CDS             260..664
                     /gene="comGD"
                     /locus_tag="ACL3GT_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HGR0517156.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSSSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            627..929
                     /gene="comGE"
                     /locus_tag="ACL3GT_001505"
     CDS             627..929
                     /gene="comGE"
                     /locus_tag="ACL3GT_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGE"
                     /protein_id="HGR0517157.1"
                     /translation="MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQE
                     EAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            892..1353
                     /gene="comGF"
                     /locus_tag="ACL3GT_001506"
     CDS             892..1353
                     /gene="comGF"
                     /locus_tag="ACL3GT_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HGR0517158.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            1331..1777
                     /gene="comGG"
                     /locus_tag="ACL3GT_001507"
     CDS             1331..1777
                     /gene="comGG"
                     /locus_tag="ACL3GT_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HGR0517159.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKAEKKNQKRSLKRKRIPSQFNYNALNPE"
     gene            1880..2467
                     /locus_tag="ACL3GT_001508"
     CDS             1880..2467
                     /locus_tag="ACL3GT_001508"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0517160.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKVILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQARLKVEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            2528..3481
                     /locus_tag="ACL3GT_001509"
     CDS             2528..3481
                     /locus_tag="ACL3GT_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0517161.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSNLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            3532..4722
                     /locus_tag="ACL3GT_001510"
     CDS             3532..4722
                     /locus_tag="ACL3GT_001510"
                     /EC_number="2.7.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008776 - acetate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006085 - acetyl-CoA biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HGR0517162.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYFAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            4723..4854
                     /locus_tag="ACL3GT_001511"
     CDS             4723..4854
                     /locus_tag="ACL3GT_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517163.1"
                     /translation="MKLKKYSIQGVGKVIFPASFSDEIVQNLAMIGFFEKYGIIVVI"
     gene            4871..5242
                     /gene="rnpA"
                     /locus_tag="ACL3GT_001512"
     CDS             4871..5242
                     /gene="rnpA"
                     /locus_tag="ACL3GT_001512"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HGR0517164.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            5217..6041
                     /locus_tag="ACL3GT_001513"
     CDS             5217..6041
                     /locus_tag="ACL3GT_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HGR0517165.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            6060..7046
                     /gene="jag"
                     /locus_tag="ACL3GT_001514"
     CDS             6060..7046
                     /gene="jag"
                     /locus_tag="ACL3GT_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HGR0517166.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            7097..7720
                     /locus_tag="ACL3GT_001515"
     CDS             7097..7720
                     /locus_tag="ACL3GT_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HI_0552 family protein"
                     /protein_id="HGR0517167.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            7851..9308
                     /locus_tag="ACL3GT_001516"
     CDS             7851..9308
                     /locus_tag="ACL3GT_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0517168.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            9331..9612
                     /locus_tag="ACL3GT_001517"
     CDS             9331..9612
                     /locus_tag="ACL3GT_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0517169.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            9689..10174
                     /locus_tag="ACL3GT_001518"
     CDS             9689..10174
                     /locus_tag="ACL3GT_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0517170.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGLYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            10191..10856
                     /locus_tag="ACL3GT_001519"
     CDS             10191..10856
                     /locus_tag="ACL3GT_001519"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HGR0517171.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            10860..11723
                     /locus_tag="ACL3GT_001520"
     CDS             10860..11723
                     /locus_tag="ACL3GT_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HGR0517172.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            11725..12429
                     /locus_tag="ACL3GT_001521"
     CDS             11725..12429
                     /locus_tag="ACL3GT_001521"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HGR0517173.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            12608..14281
                     /locus_tag="ACL3GT_001522"
     CDS             12608..14281
                     /locus_tag="ACL3GT_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0517174.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            14393..15484
                     /gene="ulaG"
                     /locus_tag="ACL3GT_001523"
     CDS             14393..15484
                     /gene="ulaG"
                     /locus_tag="ACL3GT_001523"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HGR0517175.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            15598..17574
                     /gene="tkt"
                     /locus_tag="ACL3GT_001524"
     CDS             15598..17574
                     /gene="tkt"
                     /locus_tag="ACL3GT_001524"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0517176.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            17691..17990
                     /gene="yajC"
                     /locus_tag="ACL3GT_001525"
     CDS             17691..17990
                     /gene="yajC"
                     /locus_tag="ACL3GT_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HGR0517177.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            18037..18465
                     /locus_tag="ACL3GT_001526"
     CDS             18037..18465
                     /locus_tag="ACL3GT_001526"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HGR0517178.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLCQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            18467..18877
                     /locus_tag="ACL3GT_001527"
     CDS             18467..18877
                     /locus_tag="ACL3GT_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MORN repeat-containing protein"
                     /protein_id="HGR0517179.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            19177..21828
                     /gene="adhE"
                     /locus_tag="ACL3GT_001528"
                     /gene_synonym="adhC"
     CDS             19177..21828
                     /gene="adhE"
                     /locus_tag="ACL3GT_001528"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HGR0517180.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT         6949 a         3976 c         4825 g         6344 t
ORIGIN      
        1 atgttagtag tcttgctgat tatcagcgtg cttttcttgc tctttgtacc taatctgacc
       61 aagcaaaaag aagcagtcaa tgacaaagga aaagcagctg ttgttaaggt ggtggaaagc
      121 caggcagaac tttatagctt ggataaaaat gaagatgcta ctctgagcaa gttacaagga
      181 gatgggcgca tcacggaaga acaggttaaa gcttataatg aatactatac taaaaatgga
      241 ggggcaaatc gtaaagtcaa tgattaaggc ctttaccatg ctggaaagtc tcttggtttt
      301 gggacttgtg agtatccttg ccttgggctt atccagctct gtccagtcca cttttgcagc
      361 agtagaggag cagattttct ttatggagtt tgaagaactc tatcgggaaa cccaaaaacg
      421 cagtgtagcc agtcagcaaa agactagtct aaatttagat gggcagacgc ttagcaatgg
      481 cagtcaaaag ttgacagttc ctaaaggaat tcaggcacca tcaggccaaa gtattacatt
      541 tgaccgagct gggggcaatt cgtccctggc taaggttgaa tttcagacca gtaaaggagc
      601 gattcgctat caattatatc taggaaatgg aaaaattaaa cgcattaagg aaacaaaaaa
      661 ttagggcagt gattttactg gaagcagtag tcgctctagc tatctttgcc agcattgcga
      721 ccctcctttt gggacaaatt caaaaaaata ggcaagagga agcaaaaatc ttgcaaaagg
      781 aagaagtctt gagggtagct aagatggccc tgcagacggg gcaaaatcag gtaagcatca
      841 acggagttga gattcaggta ttttctagtg aaaaaggatt ggaggtctac catggttcag
      901 aacagttgtt ggcaatcaaa gagccataag gtcaaggctt ttaccttgtt agaatccctg
      961 cttgccctca ttgtcatcag tgggggatta ctcctttttc aaactatgag tcagctcctc
     1021 atttcagaag ttcgctacca gcaacaaagc gagcaaaagg agtggctctt gtttgtggac
     1081 caacttgagg cagaattaga ccgttcgcag ttcgaaaaag tagaaggcaa tcgcctatac
     1141 atgaagcaag atggcaagga catcgccatc ggtaagtcaa agtcagacga ttttcgtaaa
     1201 accgatgcta gtggacgggg gtatcagcct atggtttatg gcctcaaatc agctcagatt
     1261 acagaggaca atcaactggt tcattttcgt ttccagtttc aaaaaggctt agaaagggag
     1321 ttcatctatc gtgtggaaaa agaagaaagt taaggcaggt gttctcctct acgcagtcac
     1381 catagcagcc atctttagtc ttttgttgca attttatttg aaccgacaaa tcgcccacta
     1441 tcaagactat gctttaaata aagaaaaatt ggttgctttt gccatggcta aacgaaccaa
     1501 ggataaagcc gagcaagaaa gtggggaaca ggtttttaat ctaggtcagg taagctatca
     1561 aaacaagaaa acaagcttgg tgacgactgt tcgtacgtct aagagccaat atgagtttct
     1621 gtttccttca gtcaaaatca aagaagagaa aagagataaa aaggaagagg tagcgaccga
     1681 ttcaagcgaa aaagcggaga aaaaaaatca gaagagaagc ctgaaaagaa agagaattcc
     1741 tagtcaattc aactataatg cgttgaatcc agaatagtcc actgtagttt ctagaaaatt
     1801 gctggaaatg gatgttaagc tccaattcat ttgtttatat cttatttcag tttactatac
     1861 tttgtgctaa actaaagata tgaaacatga ttttaaccac aaagcagaaa ctttcgactc
     1921 ccctaaaaat atcttcctcg caaacttggt atgtcaagca gtcgagaaac agattgatat
     1981 tttatcagac aaagtaattt tagatttcgg tggtggcacg ggtctattag ccttgcccct
     2041 agccaagcag gctaagtcag ttactcttgt agacatttct gagaaaatgt tggagcaagc
     2101 tcgtttgaaa gtggagcagc aagcaatcaa gaatatccag tttttggagc aagatttacc
     2161 gaaaaatccc ttggagaaag agtttgattg ccttgctgtt agtcgggttc ttcatcatat
     2221 gcctgatttg gatgcggctc tctcactgtt tcatcaacat ttgaaggaag atgggaaact
     2281 catcattgct gattttacca agacagaagc taatcatcat ggatttgatt tagctgaact
     2341 ggaaaacaag ctaattgagc atggtttttc atctgtgcat agtcagattc tctatagcgc
     2401 tgaagacctg tttcaaggaa atcactcaga attcttttta atagtagccc aaaaatcact
     2461 cgcctagtca gggagtgatt tttctataag gatggaaaaa agaagggaaa tttgataaga
     2521 taggaatatg gattttgaaa aaattgaaca agcttatacc tatttactag agaatgtcca
     2581 agttatccaa agtgatttgg cgaccaactt ttatgacgcc ttggtggagc aaaacagcat
     2641 ctatctggat ggtgaaactg agctaaacca ggtcaaagac aacaatcagg cccttaagcg
     2701 tttagcacta cgcaaagaag aatggctcaa gacctaccag tttctcttga tgaaggctgg
     2761 gcaaacagaa cccttgcagg ccaatcacca gtttacacca gatgccattg ctttgctttt
     2821 ggtgtttatt gtggaagagt tgtttaaaga ggaggaaatt actatcctcg aaatgggttc
     2881 tgggatggga attctaggcg ctactttctt gacctcgctt gataaaaagg tggattactt
     2941 gggaatggaa atggatgatt tgctgattga tctggcagct agcatggcag atgtaattgg
     3001 tttgcaggct ggctttgtcc aaggagatgc cgttcgtcca caaatgctca aagaaagcga
     3061 tgtggtcatc agtgacttgc ctgttggcta ttatcctgat gatgccgttg cgtcgcgcca
     3121 tcaagttgct tctagccaag aacatactta cgcccatcac ttgctcatgg aacaagggct
     3181 taagtacctc aagtcagacg gatacgctat ttttctagct ccgagtaatt tgttgaccag
     3241 tcctcaaagt gatttgttaa aagaatggct gaaagaagag gcgagtctgg ttgctatgat
     3301 tagtctgcct gaaaatctct ttgctaatgc caaacaatct aagactattt ttatcttaca
     3361 gaagaaaaat gaaatagcag tagagccttt tgtttatcca cttgctagct tgcaagatgc
     3421 aagtgtttta atgaaattta aagaaaattt tcaaaaatgg actcaaggta ctgaaatata
     3481 aaatagattt tgttataata gttgaaaacg cttaaaaagg ggtatcatgt tatgacaaaa
     3541 acaattgcaa tcaatgcagg aagttcaagt ttgaaatggc aattatactt aatgccagaa
     3601 gaaaaagtgt tagccaaagg tttgattgaa cgtatcggtt tgaaagattc aatttcaact
     3661 gtaaaatttg acggccgttc tgaacaacaa attttggata ttgaaaatca tacacaagcc
     3721 gttaaaattt tattggatga cttgattcgt ttcgatatta tcaaggctta tgacgagatt
     3781 acaggtgttg gacatcgtgt tgttgctggt ggagaatatt tcaaagaatc aacagttgtt
     3841 gagggagatg ttttagaaaa agttgaagag ttgagtttgt tggctcctct acacaacccg
     3901 gccaatgcag caggtgttcg tgccttcaag gaattgttgc cagacattac cagtgtagtt
     3961 gtttttgata cttccttcca cacaagtatg ccagagaaag cttatcgcta ccctctacca
     4021 acaaaatatt acacagaaaa caaggttcgt aaatacggtg ctcatggtac aagtcaccag
     4081 tttgtagcag gagaagctgc aaaactcttg ggacgtccat tagaagactt gaagttaatt
     4141 acctgtcata ttggtaacgg aggctcaatt acagctgtga aagccggcaa atctgtagac
     4201 acttctatgg ggttcactcc tcttggtggt attatgatgg gaacgcgtac aggggatatt
     4261 gatccagcta tcattcctta tttaatgcaa tatacagagg attttaacac accagaagat
     4321 atcagtcgtg ttcttaaccg tgaatcaggt cttttgggag tttctgctaa ttctagcgat
     4381 atgcgcgata tagaagcagc tgtagcagaa gggaatcacg aggctagctt ggcttatgaa
     4441 atgtatgttg accgtatcca aaaacatatc ggtcagtact ttgcagtgct aaatggagca
     4501 gatgccattg ttttcacagc aggtgtcggt gaaaatgcag agaatttccg tcgtgatgta
     4561 atctcaggga tttcgtggtt tggttgtgat gttgatgatg aaaagaatgt ctttggcgtt
     4621 acaggagaca tctcaacaga ggcagctaaa atccgtgtct tggttattcc aacagatgaa
     4681 gaattagtca ttgcccgtga cgttgaacgc ttgaaaaaat aagtgaaact aaaaaaatat
     4741 tcaatacaag gagttgggaa agttattttt ccagcttctt tttctgatga aattgtccaa
     4801 aaccttgcta tgattggctt ttttgaaaaa tatggtataa tagtagtaat ttaatagatg
     4861 gagttgagtt ttgaagaaaa actttcgtgt aaaaagagag aaagatttta aggcgatttt
     4921 caaggagggg acaagttttg ctaatcgcaa atttgtggtc taccaattag aaaaccagaa
     4981 aaaccatttt cgagtaggtc tatcagttag caaaaaactg gggaatgccg tcactagaaa
     5041 tcaaattaag cgacggattc ggcatattat ccagaatgca aaagggagtc tggtagaaga
     5101 tgtcgacttt gttgtcattg ctcgaaaagg agtcgaaacc ttgggatacg cagagatgga
     5161 gaaaaatcta ctccatgtat taaaattatc aaagatttac cgggaaggaa atgggagtga
     5221 aaaagaaact aaagttgact agtttgctag gactgtctct gttaatcatg acagcctgtg
     5281 cgactaatgg ggtaactagc gatattacag ccgaatcggc tgatttttgg agtaaattgg
     5341 tttacttctt tgcgaaaatc attcgctttt tatcgtttga tattagtatc ggagtgggga
     5401 ttattctctt tacggtcttg attcgtacag tcctcttgcc agtctttcag gtgcaaatgg
     5461 tggcttctag gaaaatgcag gaagctcagc cacgcattaa ggcgcttcga gaacaatatc
     5521 caggtcgaga tatggaaagc agaaccaaac tagagcagga aatgcgtaaa gtatttaaag
     5581 aaatgggtgt cagacagtca gattctcttt ggccgatttt gattcagatg ccggttattt
     5641 tggccttgtt ccaagcccta tcaagagttg actttttaaa gacaggtcat ttcttatgga
     5701 ttaaccttgg tagtgtggat acaacccttg ttcttccgat tttagcagca gtattcacct
     5761 ttttaagtac ttggttgtcc aacaaagctt tgtctgagcg aaatggcgct acgactgcga
     5821 tgatgtatgg gattccagtc ttgattttta tctttgcagt ttatgcgcca ggtggagtcg
     5881 ccctatactg gacagtgtct aatgcttatc aagtcttgca aacctatttc ttgaataatc
     5941 cattcaagat tatcgcagag cgcgaggccg tagtacaggc acaaaaagat ttggaaaata
     6001 gaaaaagaaa agccaagaaa aaggctcaga aaacgaaata aataaggagg aatctggtaa
     6061 tggtagtatt tacaggttca actgttgaag aagcaatcca gaaaggattg aaagaattag
     6121 atattccaag aatgaaggct catatcaaag tcatttctag ggagaaaaaa ggctttcttg
     6181 gtctatttgg taaaaaacca gcccaagtgg atattgaagc gattagtgaa acgactgttg
     6241 tcaaagcaaa tcaacaggta gtaaaaggcg ttccgaaaaa aatcaatgat ttgaacgagc
     6301 ctgtgaagac ggttagtgaa gaaaccgttg accttggtca tgtggttgat gctattaaaa
     6361 aaatagagga agaaggtcaa ggtatttctg atgaagtcaa ggctgaaatc ttaaaacatg
     6421 aaagacatgc cagcactatc ttagaagaaa ctggtcacat tgagatttta aatgaacttc
     6481 aaatcgagga agcgatgagg gaagaagcag gcgctgatga ccttgaaact gagcaagatc
     6541 aaactgaaaa tcaagacttg aaagagatgg gcttgaaggt cgagcaaagt tatgatattg
     6601 cccaggtggc tacggatgtg actgcctatg ttcaagcgat tgtggatgac atggatgttg
     6661 aagctacact ttcaaatgat tataaccgtc gtagcatcaa tctacaaatt gacaccaacg
     6721 aaccaggtcg tattatcggc taccatggta aagtcttgaa ggccttgcaa ctgttggctc
     6781 aaaattatct ttacaaccgc tattccaaaa ccttctacgt tacaatcaat gtcaatgatt
     6841 atgtcgaaca ccgtgcagaa gtcttgcaga cctatgcgca aaaattggcg attcgtgttt
     6901 tagaagaagg acgtagtcat caaacagatc caatgtcgaa tagtgaacgc aagattatcc
     6961 accgtattat ttcacgtatg gatggcgtga ccagttactc tgaaggtgat gagccaaatc
     7021 gctatgtcgt tgtagataca gaataagtaa aatcagggtt gacctgattt tttgctagct
     7081 agaggaggtt aaactgatgt tgaataagat aagagactat ttagactttg ctggtttgca
     7141 gtaccgtaat cctgataaag cgggagcaga gcgagagaag atgctggcat tccgccacaa
     7201 aggacaagag gcccgaaagg cttttacaga actggccaaa gcctttcaag caagccatcc
     7261 agaatggcaa ctccaacaga ctagtcagtg gatgaatcag gcccagcgtt tgagaccaca
     7321 tttttgggtt tatctacaga gagacggaca agtgacagaa cctatgatgg ccttacgttt
     7381 gtatgggaca tctactgact ttggaatttc tttggaagtc agtttcatcg aacgtaagaa
     7441 ggatgagcaa acactgggca agcaggccaa agttttagac attccaaccg ttaaagggat
     7501 ttattatcta acctactcta atggtcaaag tcaacggtgg gaggcgaatg aagaaaagcg
     7561 tcgtacttta cgcgagaagg tgagaagtca agaagttcga aaagttttag tgaaggtaga
     7621 tgttcctatg acagaaaatt cgtctgaaga agaaatcgta gaaggcttat tgaagtctta
     7681 ttctaaaatt cttccctatt atctagctac gagaaaataa gataatttgt aaaacatcat
     7741 aaatcataca gtccaagagt gaacagtccg ctgtgtaatt cttggtcttt ttgtttgcgc
     7801 tttcgcatta tataataaac ttacaaaaac aattcaaaag gagaacaatt atggaagtcg
     7861 tttcaagtgt tctaaattgg ttttctagca atattttgca gaatcccgca tttttcgtag
     7921 gtttattggt gttgatagga tatgcacttt tgaaaaaacc tgcccatgac gttttttcag
     7981 ggtttgttaa agcaacagta gggtatatgt tgcttaacgt gggtgctggt ggtttggtta
     8041 caacctttcg tccaatctta gcagctctta actacaaatt ccaaattggt gcagcggtta
     8101 tcgaccctta ctttggactt gctgcagcaa acaacaaaat tgcagcagag tttccagatt
     8161 ttgttggaac tgcaactaca gctctattga ttggttttgg aataaatatc ttgctcgtag
     8221 ctcttcgaaa gattacgaag gtaagaaccc tctttattac tggtcacatc atggtacaac
     8281 aagctgcaac agtatctctt atggttctat tcttagtacc acaattgcgc aatgcttacg
     8341 gtacagcagc gattggtatc atctgtggac tttactgggc agttagttca aatatgactg
     8401 ttgaggcaac tcaacgcttg actggtggtg gcggatttgc gattggtcac caacagcaat
     8461 ttgcaatctg gtttgtagat aaagtagcag gacgctttgg taagaaagaa gaaagtttag
     8521 acaatcttaa attacctaag ttcctctcaa tcttccacga tacagttgtt gcatctgcta
     8581 ccttgatgct cgtattcttc ggggccattc ttttaatctt gggtccagac attatgtcta
     8641 ataaagaagt catcacttca ggaactctat tcaatcctgc taaacaagat ttctttatgt
     8701 acattatcca aacagccttt accttctcag tttacttgtt cgttttgatg caaggtgtcc
     8761 gaatgttcgt atctgagttg acaaacgcct tccaaggtat ttcaaacaaa ttgttgccag
     8821 gttcattccc agcggttgac gttgcagctt cttatggatt tggttctcca aatgctgtct
     8881 tgtcaggatt tacctttggt ttgattggtc aattgattac aattgtcttg ctcatcgtct
     8941 ttaaaaatcc gattcttatt attacaggat ttgtaccagt gttctttgac aatgcagcca
     9001 ttgcggtcta cgctgataaa cgcggcggat ggaaagcggc tgttatcctt tcctttatat
     9061 caggtgtcct tcaagttgct ctaggagctc tttgtgtggc ccttctcgat ttggcatctt
     9121 atggtggcta ccatggaaat atcgactttg aattcccatg gcttggattt ggatatatct
     9181 tcaaatacct tggtattgtt ggttatgtac ttgtgtgtct cttcttgctt gttattcctc
     9241 aacttcaatt tgccaaagca aaagataaag agaaatatta caacggtgaa gttcaagaag
     9301 aagcttagta tctagaaaag gagaaataaa atggttaaag tattagcagc gtgcggaaat
     9361 ggaatgggtt catcaatggt tatcaagatg aaggttgaaa atgctctccg taagcttaat
     9421 caaacagatt ttacagtcaa ttcatgcagt gtcggtgaag ctaaaggttt agcagtagga
     9481 tatgacatcg taatcgcttc tcttcatttg attcaagaat tggaagggcg aactaatggg
     9541 aagttaattg gacttgataa cttgatggat gataaagaaa tcaccgaaaa actcagtcaa
     9601 gcactacagt aaaaggttgg agggggctgg acagaaactg agagttatcg tttctgtcct
     9661 tctccctctt taaataaagg aggcagatat gaatttaaaa caagctttaa ttgacaatga
     9721 ctcgatccga ctaggtttag aggctaacaa ttggaaagaa gcagtcaagg tagcagtaga
     9781 tcccttaatt gaaagtgggg caattttgcc agagtattac gatgctatca ttgaatcgac
     9841 tgaagagtat gggctttact atatcttgat gccaggtatg gctatgcccc acgctagacc
     9901 tgaagctggt gtgcaaagtg atgccttttc attgattacc ttacaaaatc ctgttgtatt
     9961 ttcagatggg aaagaggtat ctgttttgtt ggcactagca gcaacaagct caaaaattca
    10021 cacaagtgta gccattccac aaattattgc cctgtttgaa ttagaagatt ctattgcacg
    10081 tttacaggct tgccagacta aagaagatgt cttggctatg attgaagaat ctaaggatag
    10141 cccttatctc gaaggattgg atttggaaag ttagaaagag gaataaagaa atgacaaaaa
    10201 gaatacctaa tttacaagtt gcattagacc attcagactt gcaaggagcg attaaagcag
    10261 ctgtttctgt tggtcaggaa gtagatatta tcgaagctgg aactgtttgc ttgcttcaag
    10321 ttggaagtga actggctgaa gtcttgcgta gccttttccc agataagatt attgtggcag
    10381 acacaaaatg tgctgatgct ggtggaacag ttgctaaaaa taatgcggtt cgtggagcag
    10441 actggatgac ttgtatctgt tgtgcaacca tccctactat ggaagcagct ctaaaggcta
    10501 tcaagactga acgaggagaa cgaggcgaaa tccagatcga gctttatggc gattggactt
    10561 ttgaacaagc tcagctttgg ctagatgcag gtatctcaca agctatttat caccaatctc
    10621 gtgatgctct tcttgctggt gaaacttggg gtgaaaaaga ccttaataag gttaaaaaac
    10681 tcattgacat gggcttccgt gtatctgtaa caggtggtct agatgtagat actctcaaac
    10741 tctttgaagg tgttgatgtc tttaccttta tcgcaggtcg tggaattaca gaggctgcgg
    10801 atccagcagg agcagcgcgt gccttcaagg atgaaatcaa acgaatttgg gggtaaatca
    10861 tggtacgtcc aattggaatt tatgaaaagg caaccccaac acactttact tggctagaac
    10921 gtttaaattt tgccaaggag ttaggctttg attttgtcga gatgtctatt gacgaacgtg
    10981 acgagcgttt agcaagactt gactggagta aggaagaacg cttggaagtt gtcaaagcaa
    11041 tctatgaaac tggtgttcgt attccttcta tctgtttttc aggccatcgt cgctacccat
    11101 tgggttcaaa agatccagtt ctagaggaaa aatctctaga actcatgaaa aaatgtatcg
    11161 aattagctca agacttggga gttcgtacga ttcaattagc tggttacgat gtttactatg
    11221 aggaaaagtc accccagaca cgccaacgtt ttatcaaaaa tttgagaaaa gcctgtgact
    11281 gggctgaaga agctcaggtg gtacttgcta ttgaaattat ggatgatcct ttcatcaata
    11341 gcatcgaaaa atatttggct atagaaaaag agattgactc tcccttcctc tttgtatatc
    11401 cagatattgg taatgtgtct gcatggcata atgatatcta tagtgagttt tatcttggtc
    11461 atcatgccat cgcagctctc catctcaagg atacttatgc agtgacagaa agttcaaagg
    11521 gccagttccg agatgtacct ttcgggcaag gttgtgtcaa atgggaagaa gctttcgata
    11581 ttttaaagga aaccaattat aatggacctt tcctaatcga aatgtggtct gaaaattgtg
    11641 aaacagtaga agaaacacgc gcagccattc aagaggcgca agcttttctc tatccactca
    11701 ttaagaaagc aggtttgatg taagatgaat caagtaatca atgctatgcg taaacgagtc
    11761 tgtgatgcca atcaatcatt gccaaaacat ggacttgtca aatttacctg ggggaatgta
    11821 tctgaagtta atcgcgaact cggtgtcatt gttatcaaac catcaggcgt ggattatgac
    11881 gaattgacac ctgaaaacat ggtagtgact gatctagatg gtaagatcct agaaggggat
    11941 ttaagaccat cttccgacct cccaactcat gtgcaattat ataaggcttg gtcagaaatt
    12001 ggtagtgtgg ttcacaccca ttcgacagaa gctgttggtt gggctcaggc aggtcgtgat
    12061 attcctttct acggaacaac ccatgcagat tatttctacg gttcaatccc ttgcgcccgt
    12121 agtttgacca aggacgaagt agaagtggcc tatgaaaaag atactggcct ggttatcgta
    12181 gaagagtttg aacatcgcgg acttaacccg gttgaagtac caggaattgt tgtacgcaat
    12241 cacggtccat tcacctgggg caaaaatcca gagaatgctg tttatcactc tgtcgtacta
    12301 gaggaagtat caaagatgaa tcgctttaca gaacaaatca atccaagagt tggacctgct
    12361 ccccagtaca tactagaaaa acactaccaa cgtaaacatg gaccaaatgc ttattatggt
    12421 caaaagtaag aacgatgaag gaggagaaaa agataaattt agctcctctt tttacatttg
    12481 atttttattg agagtaaagt tggaattgaa gtaattttaa aagatttttt agaaatagcg
    12541 cttgatatat atatggtaaa ataaaaagaa ttgctgtgat atcaatagat ttgggggatt
    12601 ttttaatatg gtactggata aggcaagttg tgatttgctt caatatttga tggatcaaga
    12661 aacgtccaaa acgattatgg cgatttcgaa agatttgaaa gagtcaagaa ggaaaattta
    12721 ttatcacatt gacaaaatca atgctgctct ggttgacgag gcgcttcaca tcattagtat
    12781 tccacgaatt ggtattcact taacggaaga gcagagagat gcttgttgta aactattatc
    12841 ggaagtagat tcgtacgatt atatcatgag tgcgcatgaa cgtatgatga taatgttact
    12901 atggataggt atttctaaag aacgtattac gattgaaaaa ttgatagagt taacagaggt
    12961 atctaggaat actgttctca atgatttgaa tagtattcgt tatcaactaa ctttggaaca
    13021 atatcaggtg atcttgcaag tgagcaagtc acagggatac caccttcatg cccaccctct
    13081 taataaaatt cagtatcttc aatcgcttct atatcatatt tttatggaag aaaatgccac
    13141 ttttgtatct attttagaag ataagatgaa agagaggtta gatgatgagt gtttgctttc
    13201 tgttgaaatg aaccaatttt ttaaggaaca ggttccttta gttgaacaag atttagggaa
    13261 gaaaataaac catcatgaaa taacttttat gttgcaggtt ctaccttatt tgctgttaag
    13321 ctgtcataat gttgaacagt atcaagaaag acatcaggat atagagaaag aattttcttt
    13381 gataagaaaa agaatagagt atcaggtgtc taagaaatta ggagaacggt tgtttcaaaa
    13441 gtttgaaatt tctttgtcag gacttgaagt ttctcttgta gctgttctcc tcctctccta
    13501 tcgtaaggat ttggatattc atgcagaaag tgatgatttt cggcaattaa aacttgcttt
    13561 agaagaattt atctggtatt ttgaatcaca aatccgaatg gagattgaga acaaggatga
    13621 tttgttacga aatttgatga tccactgtaa agccttgtta tttagaaaga cttacggtat
    13681 tttttctaaa aatcctctaa caaaacaaat tcgatccaag tatggagaat tatttttagt
    13741 cactagaaaa tctgcggaaa ttttagaagg agcatggttt attcggctaa cagacgatga
    13801 tattgcctat ttgacgattc atattggagg atttttaaag tatacaccat cgtctcaaaa
    13861 aaatatgaaa aaagtttatc tcgtttgtga tgaaggtgtt gcggtttcga gacttttgct
    13921 gaaacaatgc aaactttatt ttccaaatga gcaaattgac actgtattta caacagaaca
    13981 atttaagagt gtggaagata ttgcacaagt tgatgtagtg attactacta atgatgattt
    14041 ggatagcaga tttccgattt taagggttaa tcctatcctt gaagcagaag atattttgaa
    14101 aatgctagac tatcttaaac acaatatatt tcgtaataag agcaaaagtt tcagtgaaaa
    14161 tctttctagt cttatttcgt cttatattgt agacagcaag ttggctagta agttccaaga
    14221 agaggttcaa acacttataa ataaagaaat agtagttcaa gcttttttgg aagatatttg
    14281 aaggacagtc caatgatgaa cacaaacctg tgtttttctt ggtctttttt agtgttttga
    14341 agggtggtat actaatctca aagataacaa ttatatccaa aggaggcaac atatgccaaa
    14401 cgtcaaagaa attacaagag agtcatggat tttagccact ttcccagagt ggggaacatg
    14461 gttgaacgaa gaaatcgaag aagaagtcgt acctgaaggc aactttgcca tgtggtggct
    14521 aggcaactgt ggtacttgga ttaagacacc agctggtgct aacgttgtca tggacctttg
    14581 gtcaaaccgt ggaaaatcaa ccaaaaaagt gaaagatatg gttcgtgggc accaaatggc
    14641 aaatatggca ggtgttcgta agttgcaacc aaacttgcgt gttcagccaa tggttatcga
    14701 tccatttgct atcaacgaac tagactatta cttagtttca cacttccaca gtgatcatat
    14761 cgacccatac acagctgcag caattctcaa caatcctaag ttagagcatg ttaagtttat
    14821 cggtccttac cactgtggac gaatctggga aggatggggt gttccaaaag aacgtatcat
    14881 cgttgttaaa ccaggtgaca ctatcgaatt aaaagatatg aagattcatg cagtagaatc
    14941 atttgaccgt acttgcttgg taactctccc agtgaacggt gctgatgaga caggcggtga
    15001 acttgctggc ttggctgtta cagatgaaga aatggctcaa aaggctgtta actatatctt
    15061 tgaaacacca ggtggaacca tctatcatgg tgcagattct cacttctcaa actattttgc
    15121 aaaacatggt aaagacttta aaattgatgt tgctttgaat aactatggtg aaaatccggt
    15181 aggtatccaa gacaaaatga catctatcga tcttcttcgt atggcagaaa atctgcgtac
    15241 caaagtcatt atcccagttc actatgatat ctggtctaac ttcatggctt ctactaatga
    15301 gattctagaa ctttggaaaa tgcgaaaaga tcgcttgcaa tacgatttcc atccatttat
    15361 ctgggaagtt ggcggtaagt acacttatcc tcaagatcaa cacttagtag aataccatca
    15421 tccacgtggt tttgatgatt gttttgaaca agactctaac attcaattta aagctttgct
    15481 ataatataaa aatattcttt ggaggttatc cgtatgttgc atgatacgga taattttcat
    15541 ataatagtaa aatagaatgt gtgattcaat aatcacctca aatagaaagg aaattctatg
    15601 tcaaatctat ctgttaatgc aattcgtttt ctaggtattg acgccattaa taaagccaac
    15661 tcaggtcatc caggtgtggt tatgggagcg gctccgatgg cttacagcct ctttacaaaa
    15721 caacttcata tcaatccagc tcaaccaaat tggattaacc gcgaccgctt tattctttca
    15781 gcaggtcatg gttcaatgct cctttatgct cttcttcacc tttctggttt tgaagatgtc
    15841 agcatggatg agattaagag tttccgtcaa tggggttcaa aaacaccagg tcacccagaa
    15901 tttggtcata cggcagggat tgatgctacg acaggtcctc tagggcaagg gatttcaact
    15961 gctactggtt ttgcccaagc agaacgtttc ttggcagcca aatataaccg tgaaggctac
    16021 aatatctttg accactatac ttacgttatc tgtggagacg gagacttgat ggaaggtgtc
    16081 tcaagcgagg cagcttcata cgcaggtttg caaaaacttg ataagttggt tgttctttat
    16141 gattcaaatg atatcaactt ggatggtgag acaaaggatt cctttacaga aagtgttcgt
    16201 gaccgttaca atgcctacgg ttggcatact gccttggttg aaaatggaac agacttggaa
    16261 gccatccatg ctgctatcga aacagcaaaa gcttcaggca agccatcttt aattgaagtg
    16321 aagacggtta ttggatatgg ttctccaaac aaacaaggaa ctaatgctgt acacggcgcc
    16381 cctcttggag cagatgaaac cgcatcaact cgccaagccc tcggttggga ttacgaacca
    16441 tttgaaattc cagaacaagt atatgctgat ttcaaagaac atgttgcaga ccgtggcgca
    16501 tcagcttatc aagcttggac taaattagtt gcagattata aagaagctca tccagaactg
    16561 gctgcagaag tagaagccat catcgacgga cgtgatccag tcgaagtgac tccagcagac
    16621 ttcccagctt tagaaaatgg tttttctcaa gcaactcgta attcaagtca agatgccttg
    16681 aatgttgtgg cagctaaatt accaaccttc ctaggtggat cagctgacct tgctcactca
    16741 aacatgactt atatcaagac ggatggactt caagacgata ccaatcgctt gaatcgtaac
    16801 attcagtttg gtgttcgtga atttgcaatg ggaacaatct tgaacgggat ggcccttcat
    16861 ggtggacttc gtgtatacgg tggaactttc ttcgtcttct ctgactatgt gaaggcagct
    16921 gtccgcttgt cagccttaca aggacttcct gtgacttatg tctttaccca tgattcaatc
    16981 gcagttgggg aagatggtcc gactcacgaa ccagttgagc atttagcagg tcttcgtgct
    17041 atgccaaatc taaatgtttt ccgtccagca gatgcgcgtg aaacgcaagc agcttggtac
    17101 cttgcagtga caagtgagaa aacaccaact gcccttgtct tgacacgtca aaacttgact
    17161 gttgaagatg gaacagactt cgacaaggtt gctaaaggtg cttatgttgt atatgaaaat
    17221 gcagccgact ttgataccat cttgattgcg acaggttcag aggttaatct tgctgtctca
    17281 gctgctaaag aattggctag tcaaggcgaa aaaatccgcg tagtcagcat gccatctaca
    17341 gatgtctttg ataaacaaga tgcagcttac aaggaagaga ttcttccaaa tgcagtccgc
    17401 cgtcgtgttg cagtcgaaat gggtgcaagt caaaactggt acaaatatgt tggtctcgat
    17461 ggtgccgttc taggtattga taccttcgga gcctctgccc cagcaccaaa agtattggca
    17521 gaatatggct ttactgtaga aaatcttgta aaaattgttc gaaacttgaa ataatcctaa
    17581 aaatcagggc gtaagctctg gtttttctta ccagaaaagt aaggtacaat cttgtaaaag
    17641 tagctgaaat ttgatatagt agtcctatgt aaaagacaaa ggagaaaaca atgaatccaa
    17701 atattacttt tttaatcatg cttgtaggta tgatggcctt gatgttcttt atgcaacgtt
    17761 ctcaaaagaa acaagctcaa aagcgtatgg aaagcttaaa taaactacaa aaaggctatg
    17821 aagtgattac aatcggtgga ctttatggaa cagtcgatga agtagatacg gagaagggaa
    17881 caatagttct tgacgtagat ggagtttact tgacttttga actagctgct atcaagacag
    17941 tattaccgct gaaagaaaca gcttcactag aaggcgcaat tgaaaaataa gacgggatca
    18001 cgaactcccg tttttctata aaagaaagga aatgggatga aaaaattagt ctttgtctgt
    18061 ctgggaaata tttgccgtag ccctatggcc gagtttgtta tgaaatcaat gacagataac
    18121 tacgaaatcc aaagtcgagc aacttcctct tgggaacatg gcaatccgat tcataagggg
    18181 actcagggaa tttttcaaga gtatgagatt ccttatgaca agaacaagac atcgcttcag
    18241 attagtaagg aagattttga agcctttgat tatattatcg gaatggacgc ttcaaatatt
    18301 tctgacttat gtcagatgtg tccagtagac tgtcaagata agatttactc attttcatct
    18361 gaaagtgttc cagacccttg gtatacagga gattttgaag aaacctatcg acgtgttcaa
    18421 gagggctgtc aagcttggtt agaacgttta gaaaaggaga gttaaggtgg aaaatcttac
    18481 gaatttttac gaaaagtatc gtgtctatct gactcgtcca cgtttagagc ttttggcagt
    18541 agttaccatt gttttttgtg ctgtactcgt cttttttcta aatattccag gaaaaggtgt
    18601 cttaaaactc gataatggaa cgattgttta tgatggcagt cttgtccgtg gtaaaatgaa
    18661 tggccaaggt accattacct tccaaaatgg agaccaatat acaggtggct tcaacaatgg
    18721 agccttcaac ggaaaaggta cctttcaatc taaagaaggc tggacctacg aaggtgattt
    18781 tgtaaatggt caggctgaag gaaaagggaa actaacaaca gaacaagaag tcgtttatga
    18841 aggaactttt aaacaaggcg tttttcaaca aaaataaagc ctccttatca aaggaggtat
    18901 tattagaatc acaaggtaag cgcttacctg taaatccctt tctttccaaa tccctcttcc
    18961 aagcaagttt gtgaaataaa aaatatttga aataaatttc acaaacttca aagataaaac
    19021 ttgataagaa aagaaaatga gaaaagtttc acaagagttt aaaaattctt tgtgaaatgt
    19081 ttatgaaact gtttacaaag ttgaaataat gcgttataat aaacttgtga aaaaattaac
    19141 aaaggatatc gttccttgaa agctatggag gaaaatatgg ctgataaaaa aactgtgaca
    19201 ccagaggaaa agaaactcgt tgctgaaaaa cacgtagatg agttggttca aaaagctcta
    19261 gttgcccttg aagaaatgcg taaattggat caagaacaag ttgactacat cgttgccaaa
    19321 gcatcagtag cagctttgga tgcccacgga gaattggctt tacatgcctt tgaagaaaca
    19381 ggacgtggtg tatttgaaga caaagcaact aagaacttgt ttgcttgtga acacgtagta
    19441 aacaatatgc gccacactaa gacagttggc gttatcgaag aagacgatgt aacaggattg
    19501 actcttattg ctgaaccagt tggtgttgtt tgtggtatta ctccaacaac aaacccaaca
    19561 tcaacagcaa tcttcaaatc attgatttca ttgaagacac gtaacccaat cgtctttgcc
    19621 ttccatccat cagcacaaga atcatctgct catgcagctc gtatcgtccg cgatgcagct
    19681 atcgcagctg gtgctcctga aaactgtgtg caatggatta ctcaaccatc tatggaagca
    19741 acaagtgccc ttatgaacca cgaaggtgtt gcgacaatcc ttgcaacagg tggtaatgcc
    19801 atggttaagg cggcttattc atgtggtaaa ccagctcttg gggtaggtgc cggaaacgtt
    19861 ccagcttatg ttgaaaaatc agcaaacatt cgtcaagcag cacacgatat cgtcatgtct
    19921 aaatcatttg ataacggtat ggtctgtgca tctgaacaag cagttatcat tgataaagaa
    19981 atttacgatg aatttgtagc agagttcaaa tcttaccaca cttactttgt aaacaaaaaa
    20041 gaaaaagctc ttcttgaaga gttctgcttc ggcgtcaaag caaacagcaa aaactgtgct
    20101 ggtgcaaaat tgaacgctga catcgttggt aaaccagcaa cttggattgc agaacaagca
    20161 ggatttacag ttccagaagg aacaaacatt cttgctgcag aatgtaaaga agttggcgaa
    20221 aatgagccat tgactcgtga aaaattgtca ccagttattg cagttttgaa atctgaaagc
    20281 cgtgaagatg gtattactaa ggctcgtcaa atggttgaat ttaacggtct tggacactca
    20341 gcagctatcc acacagctga cgaagaattg actaaagaat ttggtaaagc tgttaaagct
    20401 attcgtgtta tctgtaactc accttctact tttggtggta tcggggacgt ttacaatgcc
    20461 ttcttgccat cattgacact tggatgtggt tcttacggac gcaactcagt tggggataac
    20521 gttagtgcca ttaacctctt gaatatcaaa aaagtcggaa gacggagaaa taacatgcaa
    20581 tggatgaaac ttccttcaaa aacatacttt gaacgtgatt caattcaata ccttcaaaaa
    20641 tgtcgtgacg ttgaacgtgt catgatcgtt actgaccatg ccatggtaga gcttggtttc
    20701 cttgatcgta tcatcgaaca actggacctt cgtcgcaata aggttgttta ccaaatcttt
    20761 gcggatgtag aaccggatcc agatatcaca actgtaaacc gtggtactga gattatgcgt
    20821 gccttcaaac cagataccat catcgcactc ggtggtgggt ctccaatgga tgctgccaaa
    20881 gtaatgtggc tcttctacga gcaaccagaa gtggacttcc gtgaccttgt ccaaaaattc
    20941 atggatatcc gtaaacgtgc cttcaagttc ccattgcttg gtaagaagac taaattcatc
    21001 gcgattccaa ctacatctgg tacaggatct gaagtaacac catttgccgt tatctctgat
    21061 aaagcaaaca accgtaaata cccaatcgct gactactcat tgacaccaac tgtggcaatc
    21121 gtagatcctg ctttggtatt gacagttcca ggatttgttg ctgctgatac tggtatggac
    21181 gtattgactc acgcgacaga agcatacgta tcacaaatgg ctagtgacta cactgatggt
    21241 ttagcacttc aagccattaa attggtcttt gaaaatctcg aaagctcagt taagaatgca
    21301 gacttccact cacgtgagaa aatgcataac gcttcaacaa tcgctggtat ggcctttgcc
    21361 aatgccttcc taggtatttc tcactcaatg gcccataaga ttggtgcgca attccacaca
    21421 atccacggtc gtacaaatgc tatcttgctt ccatacgtta tccgttacaa cggtacacgt
    21481 ccagctaaga cagcaacatg gcctaagtac aactactacc gtgcagatga aaaataccaa
    21541 gatatcgcac gcatgcttgg acttccagct tctactccag aagaaggggt tgaatcttac
    21601 gcaaaagctg tctacgaact cggtgaacgt attgggatcc aaatgaattt tagagaccaa
    21661 ggaattgacg aaaaagaatg gaaagaacat tctcgtgaat tagccttcct ggcttatgaa
    21721 gaccaatgtt caccagctaa cccacgtctt ccaatggtag accatatgca agaaatcatc
    21781 gaagatgcat actatggcta caaagaaaga ccaggacgcc gtaaataatt gtttatcagt
    21841 ctagaagcaa gacaaaaact caatttgagg gaaagatcca gtaatttttc tatgataaaa
    21901 ggcatcctat caaggttttt gaacacctga taggatgcct ttttatgata ttgaggcctt
    21961 tttgcccttt ttgaaaaact agaatagaaa caaaatatat aatagattga aactggaata
    22021 gtacacttct gcttctaaaa cattgttaga attcgatttg actgtcctga tcgatttgtc
    22081 ctattcctat ttca
//
LOCUS       DBEJJV010000034        20909 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.034, whole genome shotgun sequence.
ACCESSION   DBEJJV010000034 DBEJJV010000000
VERSION     DBEJJV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.034"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..389
                     /locus_tag="ACL3GT_001529"
                     /pseudo
     CDS             1..389
                     /locus_tag="ACL3GT_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(464..1384)
                     /gene="cysK"
                     /locus_tag="ACL3GT_001530"
     CDS             complement(464..1384)
                     /gene="cysK"
                     /locus_tag="ACL3GT_001530"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HGR0517181.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYNGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1669..2304)
                     /locus_tag="ACL3GT_001531"
     CDS             complement(1669..2304)
                     /locus_tag="ACL3GT_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HGR0517182.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDNGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            2360..3658
                     /locus_tag="ACL3GT_001532"
     CDS             2360..3658
                     /locus_tag="ACL3GT_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0517183.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSNLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3655..4317
                     /locus_tag="ACL3GT_001533"
     CDS             3655..4317
                     /locus_tag="ACL3GT_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HGR0517184.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREEGASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4397..4945
                     /gene="raiA"
                     /locus_tag="ACL3GT_001534"
     CDS             4397..4945
                     /gene="raiA"
                     /locus_tag="ACL3GT_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HGR0517185.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5081..7054
                     /locus_tag="ACL3GT_001535"
     CDS             5081..7054
                     /locus_tag="ACL3GT_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HGR0517186.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7051..7503
                     /gene="rplI"
                     /locus_tag="ACL3GT_001536"
     CDS             7051..7503
                     /gene="rplI"
                     /locus_tag="ACL3GT_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HGR0517187.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7547..8899
                     /gene="dnaB"
                     /locus_tag="ACL3GT_001537"
     CDS             7547..8899
                     /gene="dnaB"
                     /locus_tag="ACL3GT_001537"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HGR0517188.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEICSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            8901..9167
                     /locus_tag="ACL3GT_001538"
     CDS             8901..9167
                     /locus_tag="ACL3GT_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HGR0517189.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9256..10374
                     /gene="cbpD"
                     /locus_tag="ACL3GT_001539"
     CDS             9256..10374
                     /gene="cbpD"
                     /locus_tag="ACL3GT_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HGR0517190.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSGG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSNNSSTV
                     GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGLWYYLGSSGAM
                     KTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10457..10559
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10630..10920
                     /locus_tag="ACL3GT_001540"
     CDS             10630..10920
                     /locus_tag="ACL3GT_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HGR0517191.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            10883..11641
                     /locus_tag="ACL3GT_001541"
     CDS             10883..11641
                     /locus_tag="ACL3GT_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0517192.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            11679..12686
                     /locus_tag="ACL3GT_001542"
     CDS             11679..12686
                     /locus_tag="ACL3GT_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HGR0517193.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            12686..13414
                     /locus_tag="ACL3GT_001543"
     CDS             12686..13414
                     /locus_tag="ACL3GT_001543"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0517194.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13533..13991
                     /locus_tag="ACL3GT_001544"
     CDS             13533..13991
                     /locus_tag="ACL3GT_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HGR0517195.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            13993..16425
                     /locus_tag="ACL3GT_001545"
     CDS             13993..16425
                     /locus_tag="ACL3GT_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HGR0517196.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            16746..17399
                     /gene="rr06"
                     /locus_tag="ACL3GT_001546"
     CDS             16746..17399
                     /gene="rr06"
                     /locus_tag="ACL3GT_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HGR0517197.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            17396..18736
                     /gene="hk06"
                     /locus_tag="ACL3GT_001547"
     CDS             17396..18736
                     /gene="hk06"
                     /locus_tag="ACL3GT_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HGR0517198.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSRLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            18819..19346
                     /locus_tag="ACL3GT_001548"
     CDS             18819..19346
                     /locus_tag="ACL3GT_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HGR0517199.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            19425..>20909
                     /gene="pspC"
                     /locus_tag="ACL3GT_001549"
     CDS             19425..>20909
                     /gene="pspC"
                     /locus_tag="ACL3GT_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HGR0517200.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSEN
                     NPTVTSSGQDISKKYADEVKSHLEKILSEIQTNLDRSKHIKTVNLINKLQDIKRTYLY
                     ELNVLEDKSKAELPSKIKAELDAAFEQFKKDTLPTEPGKKVAEAKKKVEEAEKKAKAQ
                     KEEDYRNYPTITYKTLELEIAESDVKVKEAELELVKKEADESRNEGTINQAKAKVESE
                     QAEATRLKKIKTDREKAEEEAKRRADAKEQDESKRRKSRVKRGDLGEPATPDKKENDA
                     KSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEAEKKAKDQKEEDHRNYPTITYKTLEL
                     EIAESDVEVKKAELELVKEEAKGSRNEEKVKQAKAEVESKKAEATRLEKIKTDRKKAE
                     EEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEED
                     YARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNT"
BASE COUNT         6602 a         3451 c         4760 g         6096 t
ORIGIN      
        1 ggtttaccaa tcacacgcaa ggaaatctct aattggcata tcaagacgag tcaatactat
       61 ttggagcccc tctataacct cttgcgagag agactattga ctcagccctt acttcatgcg
      121 gatgaaactt cttatagggt gctagagagt gatagtcagc tgacttacta ttggactttt
      181 ttgtctggga aagctgagaa acaagggatt acgctttacc atcatgtcct aatcgatttg
      241 ttcatatctt atttcaatcc attataaata gtgagaaata tctatcctat cttctagaat
      301 gtcttccaaa cgtggaaact ctcgtaaaca aagaggtttt agaggcttat ttaccatgga
      361 ctaaaattgt acaagaaaag tgcaaataag aaatctccag attaggaact atccgtgagt
      421 tctctagtct ggagattttt caatatactt cgttattgga cggttacaat tcataaagtg
      481 ctgtagagag ataacgttca ccgttatctg gtgctagggc aaggactttt ttacctgtac
      541 ctaatttttt ggcaacctcg atggctccgt agatagctgc agctgaggaa atccctacaa
      601 ggaagccttc ttttccacca atttcacgtc cgagtgcaag agcgtcatct gatgttacac
      661 gaacgatacc attataggct ttagtatcaa gtgtatcagg aataaatcca gctgagatac
      721 cttgaatttt gtgaggacca ggtttttcac cagatagaat agcagattca tctgcttcta
      781 ctgcaaaaac ttgaatgtta gaattttctg atttgagtgc atgagaaaca ccagaaatcg
      841 ttccaccggt acctactcca gcaacaaagg catctaatcc atctttaccg aaagcagcta
      901 gtatctcagc tcctgttgtt ctttcgtgta cttctggatt agctggattg tcaaattgaa
      961 gaggaaggaa accatcacgt tcagcagcga tttcttgagc cttagcaata gcacctttca
     1021 ttccctcgct accaggagtt aggacgagtt cagcaccata agcttggata attttacgtc
     1081 gttctacact catagtttca ggcataacga tgacgacttt atacccttta gcagcaccta
     1141 cccatgaaag tccaatacca gtgtttccac ttgttgcttc aacaatagta gaaccaggtt
     1201 tcagaatacc atcttgttca gctttttcaa tcatgctaag ggcaatacgg tcttttacag
     1261 atgaaccagg attaaatgct tcaagcttta tatagacgtc tgcagcacct tctggcacga
     1321 tgttgttaag tttaacaatc ggtgtttgac cgattaattc agtaatgttg ttataaatag
     1381 acatatgaat acctctttgt ataagatatc tttagtataa cgctatccat accatttgta
     1441 aaatatagaa atcctatcga agcgatagga tttctatata tcatagatca aagtcattaa
     1501 ttttcaagtg attgcgttca gctaattcta gtaaataggt gtgaaggaaa acgctatcag
     1561 gtttcgtttg aattgcttca ttttctagta tattttggta cgcatctttt tattttgctc
     1621 gctaaagtag ttgtgagaat gtcaacgaaa cgctgtatta ttcattgttt acactaagtt
     1681 tacaggaact tcaacctctc gtaaaccttg gtcagttaaa gtgacttttc cattaaaaaa
     1741 ctccacaagt gcagctttaa tagtttcttt ttcttcttta tcaacataaa tcatcgtatc
     1801 gacttgatct gtaaagtttg tatccagctc catgagatca tgttctttaa ggaagttact
     1861 gtactcttgg tactgagcat aagacatttg aatagcaatg ccagcctgtt cttttatttc
     1921 aataatacca atttctttga cagctaaggc gacactgccg gcgtaagcac gaattagtcc
     1981 tccagcgcct agtttaatac caccaaagta gcgtgtcacg accacacaga cattggtgag
     2041 attgtgattt tctagtaccc caagcatggg aacaccagca gtaccactag gctcaccatt
     2101 atcacttgta cgtttaattt cactacgttc tccaataata aaggcagagc agttatgtgt
     2161 cgctttgtag tgttcttttt tgatggcagt aatgaagtca cgagcctctt cttcgctata
     2221 aacacgcttg gcatggcaga taaagcgaga tttttttatt tcttcttgga cttggccgtc
     2281 ctctttaatt gtcctaaatt ccatgattta attgtactaa aaaataatct aaagtgctag
     2341 tttttacgaa tagagaagta tgaaagtaaa tttagattat ctcggtcgtt tatttactga
     2401 gaatgaatta acagaagaag aacgtcagtt ggcggagaaa cttccagcaa tgagaaagga
     2461 gaaggggaaa cttttctgtc aacgttgtaa tagtactatt ctagaagaat ggtatttgcc
     2521 catcggtgct tactattgtc gagagtgctt gctgatgaag cgagtcagaa gtgatcaaac
     2581 tttatactat tttccgcagg aggattttcc gaagcaagat gttctcaaat ggcgcggcca
     2641 attaactcct tttcaagaga aggtgtcaga gggactgctt caagcagtag acaagcaaaa
     2701 gccaacctta gttcatgcgg taacaggagc tggaaagaca gaaatgattt atcaagtagt
     2761 ggctaaagtg atcaatgcgg gtggtgcagt gtgtttggct agtcctcgca tagatgtttg
     2821 tttggagctg tacaagcgcc tgcaacagga tttttcttgc gggatagctt tgctacatgg
     2881 agaatcggaa ccttattttc gaacaccact agttgttgca acaacccatc agttattgaa
     2941 gttttatcaa gcttttgatt tgctgatagt ggatgaagta gatgcttttc cttatgttga
     3001 taatcccacg ctttaccacg ctgtcaagaa tagtgtaaag gagaatggat tgagaatctt
     3061 tttaacagcg acttcgacca atgagttaga taaaaaggtc cgtttaggag aactaaaaag
     3121 actgagttta ccgagacggt ttcatggaaa tccgttgatt attccaaaac caatttggtt
     3181 atcggatttt aatcgctact tagacaagaa tcgtttgtca ccaaagttaa agtcctatat
     3241 tgagaagcag agaaagacag cttatccgtt actcattttt gcttcagaaa ttaagaaagg
     3301 ggagcagtta gaagaaatct tacaggagca atttccaaat gagaaaattg gctttgtatc
     3361 ttctgtaaca gaggatcgat tagagcaagt acaagctttt cgagatggag aactgacaat
     3421 acttatcagt acgacaatct tggagcgtgg agttaccttc ccttgtgtgg atgttttcgt
     3481 agtagaggcc aatcatcgtt tgtttaccaa gtctaatttg attcagattg gtggacgagt
     3541 tggacgaagc atggatagac cgacaggaga tttgcttttc ttccatgatg ggttaaatgc
     3601 ttcaatcaag aaggcgatta aggaaattca gatgatgaat aaggaggctg gtctatgaag
     3661 tgcttgttat gtgggcagac tatgaagact gttttaactt ttagtagtct cttacttctg
     3721 aggaatgatg actcttgtct ttgttcagac tgtgattcta cttttgaaag aattggggaa
     3781 gagaactgtc caaattgtat gaaaacagag ttgtcaacaa agtgtcaaga ttgtcaactt
     3841 tggtgtaaag aaggagttga agtcagtcat agagcgattt ttacttacaa tcaagctatg
     3901 aaggattttt tcagtcggta taagtttgat ggagacttcc tgttaagaaa agttttcgct
     3961 tcatttttaa gtgaggagtt gaaaaagtac aaagagtatc aatttgttgt aattccccta
     4021 agtcctgata gatatgctaa tagaggattt aatcaggttg agggcttggt agaggcagca
     4081 ggctttgagt atctggattt attagagaaa agagaagagg gagccagttc ttctaaaaat
     4141 cgttcagagc gcttggggac agaacttcct ttctttatta aaagtggagt cactattcct
     4201 aaaaaaatcc tacttataga tgatatctat actacaggag caactataaa tcgtgttaag
     4261 aaactgttgg aagaagctgg tgctaaggat gtaaaaacat tttcccttgt aagatgagga
     4321 aaaaatttgc aaaaatagaa tgaaagcgtt ataataaaat cataaaaaca aaaatgttta
     4381 gaaagaaggt actcatatga ttaaatatag tatccgtggt gaaaacctag aagtaacaga
     4441 agcaattcgt gattatgtag tttctaaact cgaaaagatc gaaaagtact tccaaccaga
     4501 acaagagttg gatgcccgaa ttaacttaaa agtttatcgt gaaaaaacgg ctaaagtgga
     4561 agtaacgatt ccgcttggat ctattactct ccgcgcagaa gatgtatctc aagatatgta
     4621 tggttcaatt gaccttgtaa ctgataaaat tgaacgtcag attcgtaaaa ataaaacaaa
     4681 aatcgagcgt aaaaataaaa ataaggtagc aactggtcaa ttatttacag atgctttggt
     4741 ggaagattca aatgttgtcc agtctaaagt tgttcgttca aaacaaattg atttaaaacc
     4801 aatggatttg gaagaagcaa ttctacaaat ggatttattg gggcatgatt tctttatcta
     4861 tgtggatgtt gaagatcaaa caaccaatgt gatttatcgt cgtgaggatg gcgaaattgg
     4921 tttgttagag gttaaagaat cttaatttca atatgtgtaa aggtaggttt actgaattgt
     4981 aaactacctt tttcttataa ttgatagaat tactgattac acttttaaaa agtcgctttt
     5041 tgaggggtat tatggtataa tgggtgccaa gaggttttga atgaaaaaat tttatgtaag
     5101 tccaattttt cctattctag taggattgat tgcgtttgga gtcttatcca ctttcattat
     5161 ttttgttaat aataatctgt tgacggtttt aattttgttt ctttttgtag gaggctatgt
     5221 ttttttattt aagaaactga gagtgcatta tacaaggagt gatgtagaac agatacagta
     5281 tgtaaaccac caagcggaag aaagtttgac agctctattg gaacagatgc ctgtaggtgt
     5341 tatgaaattg aatttatctt ctggagaggt tgagtggttt aatccctatg ctgaattgat
     5401 tttgaccaag gaagatggtg attttgattt agaagctgtt caaacgatta tcaaggcttc
     5461 agtaggaaat ccgtctactt atgccaagct tggtgagaag cgttatgctg ttcatatgga
     5521 tgcttcttcc ggtgttttgt attttgtaga tgtatccagg gaacaagcca taacagatga
     5581 attggtaaca agtcgaccag tgattgggat tgtctctgtg gataattatg atgatttgga
     5641 ggatgcaact tctgagtcag atattagtca aatcaatagt tttgtagcta attttatatc
     5701 agagttttca gaaaaataca tgatgttttc tcgtcgggta agtatggatc gattttatct
     5761 atttactgac tacacggtgc ttgagggctt gatgaatgat aaattttctg ttattgatgc
     5821 tttcagagaa gagtcgaaac agagacagtt gcccttgacc ttaagtatgg gattttctta
     5881 tggcgatgga aatcatgatg agatagggaa agttgctttg ctcaatttga acttggctga
     5941 agtacgtggt ggcgaccagg tggttgttaa ggaaaacgac gaaacgaaaa atccagttta
     6001 ttttggtggt gggtctgctg cttcaatcaa gcgtacacgg actcgtacgc gcgctatgat
     6061 gacagctatt tcagataaga ttcggagtgt agatcaggtt tttgtagtcg gtcacaaaaa
     6121 tttagacatg gatgctttgg gctctgctgt aggtatgcag ttgttcgcca gcaatgtgat
     6181 tgaaaatagc tatgctcttt atgatgaaga acaaatgtct ccagatattg aacgagctgt
     6241 ttcattcata gaaaaagaag gagttacgaa gttgttgtct gttaaggatg caatggggat
     6301 ggtgaccaat cgttctttgt tgattcttgt agaccattca aagacagcct taacattatc
     6361 aaaagaattt tatgatttat ttacccaaac cattgttatt gaccaccata gaagggatca
     6421 ggattttcca gataatgcgg tcattactta tatcgaaagt ggtgcaagta gtgccagtga
     6481 gttggtaacg gaattgattc agttccagaa ttctaagaaa aatcgtttga gtcgtatgca
     6541 agcaagtgtt ttgatggctg gtatgatgtt ggatactaaa aatttcacct cgcgagtaac
     6601 tagtcggaca tttgatgttg ctagctatct cagaacgcgc ggaagtgata gtattgctat
     6661 ccaggaaatc gctgcgacag attttgaaga atatcgtgag gtcaatgaac ttattttaca
     6721 ggggcgtaaa ttaggttcag atgtactaat agcagaggct aaggacacga aatgctatga
     6781 tacagttgtt attagtaagg cagcagatgc catgttagcc atgtcaggta ttgaagcgag
     6841 ttttgttctt gcgaagaata cacaaggatt tatctctatc tcagctcgaa gtcgtagtaa
     6901 actgaatgta caacggatta tggaagagtt aggcggtgga ggccacttta atttggcagc
     6961 agctcaaatt aaagatgtaa ccttgtcaga agcaggtgaa aaactgacag aaattgtatt
     7021 aaatgaaata aaggaaaagg agaaagaaga atgaaagtaa tctttttagc agatgttaaa
     7081 ggaaaaggta aaaaaggcga aattaaggaa gtaccaacag ggtatgcgca aaactttctt
     7141 atcaaaaaga atctagccaa agaagcgact gctcaagctg taggtgaact tcgtggtaaa
     7201 caaaaatcgg aagaaaaagc tcacgctgag atgattgcag aaggaaaagc aattaaagca
     7261 caacttgaag cagaagaaac tgttgtagaa tttgttgaaa aagttggtcc agatggtcgt
     7321 acctttggtt ctattaccaa taagaagatt gcagaagaat tgcaaaagca atttggaatt
     7381 aagattgata aacgtcatat tcaagtacaa gctccgattc gagcggttgg tttgattgat
     7441 gtgccagtga aaatctatca agatatcaca agtgtaatca atcttcgtgt gaaagaagga
     7501 taagtttaca ccttcttgac aagattgtaa aaggaaggga agtctgatgg cagaagtaga
     7561 agagttacga gtacaacctc aagatatctt agctgagcaa tccgttttag gggctatctt
     7621 tattgatgag agtaaacttg tttttgtgcg agaatacatt gagtctcggg acttttttaa
     7681 gtatgcccat cgtttgattt tccaagccat ggtcgattta tccgatcgtg gtgatgccat
     7741 agatgcaaca acggttcgta ctatccttga taatcaaggt gatttacaga atattggtgg
     7801 cttgtcttac ttggttgaga ttgttaattc tgtgccaact tctgctaatg cggagtatta
     7861 tgctaagatt gttgcagaaa aagcaatgct acgtcgttta attgccaagt tgacagagtc
     7921 tgtcaaccaa gcttacgaag cgtcacaacc agctgatgaa attattgctc aggcagaaaa
     7981 agggctgatt gatgtcagtg aaaatgcaaa tcgaagcggg tttaagaaca ttcgagatgt
     8041 gttgaatctc aactttggaa atctggaagc tcgctcgcaa caaacgaccg atattacagg
     8101 tattgcgaca ggttatcgtg atttggatca tatgacaaca ggacttcatg aggaggagtt
     8161 gattatctta gcagctcgtc cagcagttgg taagacagca tttgccttga atatcgctca
     8221 gaacattggg actaagttgg acaaaacggt tgctattttt tcactcgaaa tgggtgcgga
     8281 aagcttggta gatcgtatgt tagctgcaga aggcttggtg gagtcacatt ctatccgtac
     8341 agggcaattg acagatgagg agtggcaaaa atatactatt gctcagggta atctagctaa
     8401 cgccagtatc tatatcgatg atacgccagg tattcggatt acagagattt gttctcgttc
     8461 tcgtaaattg gctcaagaaa ctggaaatct tggtttgatt ttgatagact atttacaact
     8521 tatcacggga actggtcgag aaaatcgtca acaagaagtt tctgaaattt ctcgtcagtt
     8581 gaaaatacta gccaaggaat tgaaggttcc agtaatcgct ctgagtcagc tttctcgtgg
     8641 tgtagaacaa cgtcaggaca agagaccggt cttgtctgat attcgtgaat ctgggtctat
     8701 tgagcaggac gctgatatcg tagcttttct ctatcgcgat gactactatg aacgtggtgg
     8761 tgaagaagag gagggtatcc caaataataa ggtggaagtt attatcgaga aaaaccgtag
     8821 tggagctcgt ggaacagtgg aattgatttt ccaaaaagaa tacaataaat tttcaagtat
     8881 ctcaaagagg gaggcataag atgtcagatg catttacaga tgtagccaag atgaaaaaaa
     8941 tcaaagaaga aatcaaggca catgagggac aagtcgtaga aatgactttg gagaatggtc
     9001 gtaagcgcca aaaaaataga ttgggtaagc taattgaagt ttatccatcc ctatttattg
     9061 tggagtttgg ggatgtggaa ggagataaac aagttaatgt ttacgttgaa tcctttactt
     9121 actcagatat tcttacagaa aagaatttga ttcattatct tgactaaagt gagaaatttt
     9181 ctcacttttt cttttttctc cgaataattt aggtgaaggc aatcatcgct ttatattatt
     9241 tttcaaggag gaagaatgaa aattttaccg tttatagcaa gaggaacaag ttattacttg
     9301 aagatgtcag ttaaaaagct tgttcctttt ttagtagtag gattgatgct agcagctggt
     9361 gatagtgtct atgcctattc cggaggaaat ggatcgattg cgcgtgggga tgattatcct
     9421 gcttattata aaaatgggag ccaggagatt gatcagtggc gcatgtattc tcgtcagtgt
     9481 acttcttttg tagcctttcg tttgagtaat gtcaatggtt ttgaaattcc ggcagcttat
     9541 ggaaatgcga atgaatgggg acatcgtgct cgtcgggaag gttatcgtgt agataataca
     9601 ccgacgattg gttccattac ttggtctact gcaggaactt atggtcatgt tgcctgggtg
     9661 tcaaatgtaa tgggagatca gattgagatt gaggaatata actatggtta tacagaatcc
     9721 tataataaac gaattataaa agcaaacacg atgacaggat ttattcattt taaagatttg
     9781 gatggtggca gtgttgggaa tagtcaatcc tcaacttcaa caggcggaac tcattatttt
     9841 aagaccaagt ctgctattaa aactgaaccc ctagttagtg caactgtgat tgattactat
     9901 tatcctggag agaaggttca ttatgatcaa attctcgaaa aagacggcta caagtggttg
     9961 agttatacgg cttataacgg aagtcgtcgc tatatacagc tagagggagt gacttcttca
    10021 caaaattatc agaatcaatc aggaaatatc tctagctatg gatccaataa tagttcaact
    10081 gtcggttgga agaaaataaa tggtagttgg tatcatttca aatcaaatgg ttctaaatca
    10141 acaggatggc tgaaagacgg ttctagctgg tattatttga aattatctgg tgaaatgcag
    10201 acaggatggt taaaggaaaa tggtttgtgg tattatctgg gtagttcagg ggcaatgaaa
    10261 acaggctggt accaggtctc tggtaagtgg tattattctt actcttcagg cgccttagct
    10321 gttaatacga cggtggatgg ctacagagta aacagtgatg gagaacgagt atagaaaatt
    10381 ggagtaggag aaatttcctg ctcttttctg taagcagttt ccttgacatt tttcttattt
    10441 tgcgctatca tatatacata taatatatgg gagtctgtgt acagtctgag aggaagtgtt
    10501 aaacttcgac cgcacctgat ctgggtaatg ccagcggagg gaacgatact tagtctaatt
    10561 ttgcaccttt tccatgtatg gtaaaggttt ttcttttttt taaaaggaaa acgagaagag
    10621 gaggttctta tgaaagcaag cattgccttg caagttttac ccctagcaca ggggattgat
    10681 cggatagctg ttattgatca ggtcattgct tatctgcaaa ctcaagaagt gacgatggta
    10741 gtgacaccat ttgaaacggt cttggaaggg gagtttgatg agcttatgcg cattctaaaa
    10801 gaagcgctgg aagtggcagg gcaggaggca gacaatgtct ttgccaatgt caaaataaat
    10861 gtaggagaga ttttaagtat tgatgagaaa cttgaaaagt atactgagac gacacattag
    10921 tctattgggc tttctcggag tattgtcaat ctggcagtta gcaggttttc ttaaacttct
    10981 ccccaagttt atcctgccga cacctcttga aattctccag ccctttgttc gtgacagaga
    11041 atttctctgg caccatagct gggcgacctt gagagtggct ttactggggc tgattttggg
    11101 agttttgatt gcctgtctta tggctgtgct catggatagt ttgacttggc tcaatgacct
    11161 gatttaccct atgatggtgg tcattcagac cattccgacc attgccatag ctcctatcct
    11221 ggttttgtgg ctgggttatg ggattttgcc caagattgtc ttgattatct taacaacaac
    11281 ctttcccatc atcgttagta ttttggacgg ttttaggcat tgcgacaagg atatgctgac
    11341 tttgtttagt ctgatgcgag caaacccttg gcaaatcctg tggcatttta aaatcccggt
    11401 tagcctgcct tacttttatg caggtctgag ggtcagtgtc tcctacgcct ttatcacaac
    11461 tgtggtatct gagtggttgg gaggttttga aggtcttggt gtttatatga ttcagtctaa
    11521 aaaactgttt cagtatgata ccatgtttgc cattattatt ctggtgtcga ttatcagtct
    11581 tttgggtatg aagctggtcg atatcagtga aaaatatgtg attaaatgga aacgtactta
    11641 aaatagagcg tttttgaaaa agaaaagagg aaatcaaaat gaagaaaaca tggaaagtgt
    11701 ttttaacgct tgtaacagct cttgtagctg ttgtgcttgt ggcctgtggt caaggaactg
    11761 cttctaaaga caacaaagag gcagaactta agaaggttga ctttatccta gactggacac
    11821 caaataccaa ccacacaggg ctttatgttg ccaaggaaaa aggttatttc aaagaagctg
    11881 gagtggatgt tgatttgaaa ttgccaccag aagaaagttc ttctgacttg gttatcaacg
    11941 gaaaggcacc atttgcagtg tatttccaag actacatggc taagaaattg gaaaaaggag
    12001 caggaatcac tgccgttgca gctattgttg aacacaatac atcaggaatc atctctcgta
    12061 aatctgataa tgtaagcagt ccaaaagact tggttggtaa gaaatatggg acatggaatg
    12121 acccaactga acttgctatg ttgaaaacct tggtagaatc tcaaggtgga gactttgaga
    12181 aggttgaaaa agtaccaaat aacgactcaa actcaatcac accgattgcc aatggcgtct
    12241 ttgatactgc ttggatttac tacggttggg atggtatcct tgctaaatct caaggtgtag
    12301 atgctaactt catgtacttg aaagactatg tcaaggagtt tgactactat tcaccagtta
    12361 tcatcgcaaa caacgactat ctgaaagata acaaagaaga agctcgcaaa gtcatccaag
    12421 ccatcaaaaa aggctaccaa tatgccatgg aacatccaga agaagctgca gatattctca
    12481 tcaagaatgc acctgaactc aaggaaaaac gtgactttgt catcgaatct caaaaatact
    12541 tgtcaaaaga atacgcaagc gacaaggaaa aatggggtca atttgacgca gctcgctgga
    12601 atgctttcta caaatgggat aaagaaaatg gtatccttaa agaagacttg acagacaaag
    12661 gcttcaccaa cgaatttgtg aaataatgac agaaattaga ctagagcacg tcagttatgc
    12721 ctatggtcag gagaggattt tagaggatat caacctacag gtgacttcag gcgaagtggt
    12781 ttccatccta ggcccaagtg gtgttggaaa gaccaccctc tttaatctaa tcgctgggat
    12841 tttagaagtt cagtcaggga gaattgtcct tgatggtgaa gaaaatccca aggggcgcgt
    12901 gagttatatg ttgcaaaagg atctgctctt ggagcacaag acggtgcttg gaaatatcat
    12961 tctgcccctc ttgattcaaa aggtggataa ggcagaagct atttcccgag cggataaaat
    13021 tcttgcgacc ttccagctga cagctgtaag agacaagtat cctcatgaac ttagcggtgg
    13081 gatgcgccag cgtgtagcct tactccggac ctaccttttt gggcacaagc tctttctctt
    13141 agatgaggcc tttagcgcct tggatgagat gacaaagatg gaactccacg cttggtatct
    13201 tgagattcac aagcagttgc agctaacaac cctgatcatc acgcatagta ttgaggaggc
    13261 cctcaatctc agcgaccgca tctatatctt gaaaaatcgc cctgggcaga ttgtttcaga
    13321 aattaaacta gattggtctg aagatgagga caaggaagtc caaaagattg cctacaaacg
    13381 tcaaatcttg gcagaattag gcttagataa gtagaaaaat agggagttgg tgaagattat
    13441 cctttaccag cgcccttttt cttttaaaaa tgagaaaatt tcggtataat agtcaaacaa
    13501 ggtcaaggtt taaagagaga ggtgggtttg ttatgagatt taaaaataca tcggatcata
    13561 ttgaggccta catcaaggcg attttagatc aatctggtat cgtggagttg caacggagtc
    13621 agttggcaga tacctttcag gttgttccta gtcagattaa ctacgtgatc aagacacgct
    13681 ttacggaaag tagaggctac ttggttgaaa gtaagcgtgg tggcggaggc tacattcgta
    13741 taggacggat tgagttttct agtcatcatg aaatgctccg ggagctgctt tactcgattg
    13801 gtgagcgagt cagtcaagaa atttatgagg atattctcca gcttttggtt gagcaggaat
    13861 tgatgaccaa gcaggagatg aatttgctag aatcagtagc tttggatcgc gttttaggag
    13921 aagaagctcc agttgttcga gcaaacatgc tacgtcagat catacaagag gtagatagaa
    13981 aagggaagta agatgaacta ttcaaaagca ttgaatgaat gtatcgaaag tgcctacatg
    14041 gttgctggac attttggagc tcgttatcta gagtcttggc acttgttgat tgccatgtct
    14101 aatcacagtt atagtgtagc aggggcaact ttaaatgatt atccgtatga gatggaccgt
    14161 ttagaagagg tggctttgga actgactgaa acggactata gccaggatga aacctttacg
    14221 gaattgccgt tctcccgtcg tttgcaggtt ctttttgacg aagcagagta tgtagcgtca
    14281 gtggtccatg ctaaggtgct agggacagag cacgtcctct atgcgatttt gcatgatggc
    14341 aatgccttgg cgactcgtat cttggagagg gctggatttt cttatgaaga caagaaagat
    14401 caggtcaaga ttgctgctct tcgtcgaaat ttagaagaac gggcaggctg gactcgtgaa
    14461 gatctcaagg ctttacgcca acgccatcgt acagtagctg acaagcaaaa ttctatggcc
    14521 aatatgatgg gcatgccgca gactcctagt ggtggtctcg aggactatac gcatgatttg
    14581 acagagcaag cgcgttctgg caagttagaa ccagtcatcg gtcgggacaa ggaaatctca
    14641 cgtatgattc aaatcttgag ccggaagact aagaacaacc ctgtcttggt tggggatgct
    14701 ggtgtcggga aaacagctct ggcgcttggt cttgcccagc gtattgctag tggtgacgtg
    14761 cctgcggaaa tggctaagat gcgcgtgtta gaacttgatt tgatgaatgt cgttgcaggg
    14821 acacgcttcc gtggtgactt tgaagaacgc atgaataata tcatcaagga tattgaagaa
    14881 gatggccaag tcatcctctt tatcgatgaa ctccacacca tcatgggttc tggtagcgga
    14941 attgattcga ctctggatgc ggccaatatc ttgaaaccag ccttggcgcg tggaactttg
    15001 agaacggttg gtgccaccac tcaggaagaa tatcaaaaac atatcgaaaa agatgcggca
    15061 ctttctcgtc gtttcgctaa agtgacgatt gaagaaccaa gtgtggcaga tagtatgact
    15121 attttacaag gtttgaaggc gacttatgag aaacatcacc gtgtacaaat cacagatgaa
    15181 gcggttgaaa cagcggttaa gatggctcat cgttatttaa ccagtcgtca cttgccagac
    15241 tctgctatcg atctcttgga tgaggcggca gcaacagtgc aaaataaatc aaagcatgta
    15301 aaagcagacg attctgactt gagtccagct gacaaggcct tgatggatgg caagtggaaa
    15361 caggcagccc agctaatcgc aaaagaagag gaagtgcctg tctataaaga cttggtgaca
    15421 gagtctgata ttttgaccac cttgagtcgc ttgtcaggta tccccgttca aaaactgact
    15481 cagactgatg ccaagaaata cttaaacttg gaagctgaac tgcacaaacg tgtcatcggt
    15541 caagaccaag ctgtttcaag tattagtcgt gccattcgcc gcaatcagtc aggaattcgc
    15601 agtcacaagc gtccgatcgg ttcctttatg ttcctaggac ccacaggtgt cggtaagacc
    15661 gagttggcca aggctttggc agaagttctc tttgatgacg aatcagccct tatccgcttt
    15721 gatatgagtg agtatatgga gaaattcgca gccagccgtc taaatggagc tcctccaggc
    15781 tatgtgggtt acgaagaagg tggggagttg acagagaagg ttcgcaataa accctattcc
    15841 gttctcctct ttgatgaggt agagaaggcc catccagata tctttaatgt tctcttgcag
    15901 gttctggatg acggtgtctt gacagatagc aagggacgca aggtcgattt ttcaaatacc
    15961 attatcatta tgacatcgaa cttaggtgcg actgcccttc gtgatgataa gactgttggt
    16021 tttggggcta aggatattcg ttttgaccag gaaaatatgg aaaaacgcat gtttgaagaa
    16081 ctgaaaaaag cttatagacc ggaattcatc aaccgtattg atgagaaggt ggtcttccat
    16141 agcctatcta gtgaccatat gcaggaagtg gtgaagatta tggtcaagcc tttagtggca
    16201 agtttggctg aaaaaggcat tgacttgaaa ttacaagctt cagctctgaa attgttagca
    16261 aatcaaggat atgacccaga gatgggagct cgcccacttc gcagaaccct gcaaacagaa
    16321 gtggaggaca agttggcaga acttcttctc aagggagatt tagtggcagg cagcacactt
    16381 aagattggtg tcaaagcagg ccagttaaaa tttgatattg cataaaagaa taaaagtacc
    16441 agcatctgac cataagtcac agtggagtga aactcaatga aaatcaaaga gcaaactagg
    16501 cagctagccg caggttgctc aaaacactgt tttgaggttg cagatagagc tgacgtggtt
    16561 tgaagagatt tttgaagagt ataagctgca agatgaatga ttttcttgta ttgacgttgt
    16621 tgttgacaaa aagtagcgga taaatgaaat ccattccatt atcatagatg ataggctggt
    16681 aggaaatttt caaatagcat acagaaaata gatgtatgga gttctggtag tagaaaggga
    16741 gagagatgaa cattttagtt gcagatgacg aggaaatgat tagagaagga attgcagcat
    16801 ttctgacaga agagggttat catgtcatta tggctaagga tggacaagag gtcttggaaa
    16861 aatttcaaga tctccctatc catctcatgg tactggattt aatgatgcct aggaagagtg
    16921 gttttgaagt gttaaaagaa atcaatcaaa agcacgatat tcctgtcatc gtcttgagtg
    16981 ctctgggaga tgaaactact cagtcacagg tatttgatct ctatgctgat gatcatgtga
    17041 caaaaccttt ttctttggta ctgcttgtca agcgtattaa ggcgcttatc agacgttact
    17101 acgtcataga ggatctttgg cgatatcagg atgtaacagt ggattttacc tcttacaaag
    17161 cacattataa aaatgaagaa attgatctca aaccaaagga attactggta ctaaagtgtt
    17221 tgattcagca taaaaatcaa gttttaagta gagagcagat attggaagaa atttcaaaag
    17281 atgtagctga tttaccttgt gatagggtcg ttgatgtcta tattcgtact cttcgcaaaa
    17341 aattagcttt agattgtatc gtgactgtga aaaatgttgg gtataagatt agcttatgat
    17401 aaaaaatcct aaattattaa ccaagtcttt tttaagaagt tttgcaattc taggtggtgt
    17461 tggtctagtc attcatatag ctatttattt gacctttcct ttttattata ttcaactgga
    17521 gggggaaaag tttaatgaga gcgcaagagt gtttacggag tatttaaaga ctaagacatc
    17581 tgatgaaatt ccaagcttac tccagtctta ttcaaagtcc ttgaccatat ctgctcacct
    17641 taaaagagat attgtagata agcggctccc tcttgtgcat gacttggata ttaaagatgg
    17701 aaagctatca aattatatcg tgatgttaga tatgtctgtt agtacagcag atggtaaaca
    17761 ggtaaccgtg caatttgttc acggggtgga tgtctacaaa gaagcaaaga atattttgct
    17821 tttgtatctc ccatatacat ttttggttac aattgctttt tcctttgttt tttcttattt
    17881 ttatactaaa cgcttgctca atcctctttt ttacatttca gaagtgacta gtaaaatgca
    17941 agatttggat gacaatattc gttttgatga aagtaggaaa gatgaagttg gtgaagttgg
    18001 tgaagttgga aaacagatta atggtatgta tgagcacttg ttgaaggtta ttcatgagtt
    18061 ggaaagtcgt aatgagcaaa ttgtaaaatt gcaaaatcaa aaggtttcct ttgtccgtgg
    18121 agcatcacat gagttgaaaa cccctttagc cagtcttaga attatcctag agaatatgca
    18181 gcataatatt ggagattaca aagatcatcc aaaatatatt gcaaagagta taaataagat
    18241 tgaccagatg agccgcttat tggaagaagt actggagtct tctaaattcc aagagtggac
    18301 agagtgtcgt gagaccttga ctgttaagcc agttttagta gatattttat cacgttatca
    18361 agaattagct cattcaatag gtgttacaat tgaaaatcaa ttgacagatg ctaccagggt
    18421 cgtcatgagt cttagggcat tggataaggt tttgacaaac ctgattagta atgcaattaa
    18481 atattcagat aaaaatgggc gcgtaatcat atccgagcaa gatggctatc tctctatcaa
    18541 aaatacatgt gcgcctctaa gtgatcaaga actagaacat ttatttgata tattctatca
    18601 ttctcaaatc gtgacagata aggatgaaag ttctggtttg ggtctttaca ttgtgaataa
    18661 tattttagaa agctatcaaa tggactatag ttttctccct tatgaacacg gtatggaatt
    18721 taagattagc ttgtagacag attagttttt tattaaagtt catatagggt taacataagt
    18781 gtgttattct ttgtgtagat aaaagaaagg atactaatat ggtattagcg attattttag
    18841 taacattctt tattcgattg atttttttaa agcgttcgat agagaatgag aaacgaatcc
    18901 ttagcaatgg cgggaaagaa tttggagttg agaatacaaa acgattaact atggctcata
    18961 ttgtttttta tctctcttgc ttggttgagg caatggtgca caagacaatt tttgatggca
    19021 tgggcatggt tggtttggtc ttgcttattt tttctatgct gatgttgatg ttggtgattc
    19081 acttgttggg agatatttgg acagtgaagc ttatgcttgt caataatcac aaatatgtag
    19141 atcatatctt gtttaggaca gtaaaacacc ctaattactt tttaaatatt ttacctgagt
    19201 tgattggctt gaccttgttg agtcatgctt atgtgacttt tgttttagtt tttccagttt
    19261 atgcagttat tttgtatcga cgaatagctg aagaggaaaa gctattacat gaagttataa
    19321 tcccaaatgg aagcataaag agataaatac aaaattcgat ttatatacag ttcatattga
    19381 agtgatatag taaggttaaa gaaaaaatat agaaggaaat aaacatgttt gcatcaaaaa
    19441 gcgaaagaaa agtacattat tcaattcgta aatttagtat tggagtagct agtgtagtag
    19501 ttgctagctt gttcttagga ggagtagtcc atgcagaagg ggttagaagt gagaataacc
    19561 ccacggttac atctagtggg caagatatat cgaagaagta tgctgatgaa gtcaagtcac
    19621 atctagaaaa aatattgagt gagatccaaa caaatttaga tagaagtaaa catatcaaaa
    19681 ctgtaaatct aattaacaaa ttgcaagaca ttaagagaac gtatttgtat gaattaaatg
    19741 ttttagaaga taagtcgaaa gctgagttgc cgtcaaaaat aaaagcagag ttagacgcag
    19801 cttttgagca gtttaaaaaa gatacattac caacagaacc aggaaaaaag gtagcagaag
    19861 ctaagaagaa ggttgaagaa gctgagaaaa aagccaaggc tcaaaaagaa gaagattacc
    19921 gtaactaccc aaccattact tacaaaacgc ttgaacttga aattgctgag tccgatgtga
    19981 aagttaaaga agcggagctt gaactagtaa aaaaggaagc tgacgaatct cgaaacgagg
    20041 gcacaattaa ccaagcaaaa gcgaaagttg agagtgaaca agctgaggct acaaggttaa
    20101 aaaaaatcaa gacagatcgt gaaaaagcag aagaagaagc taaacgaaga gcagatgcta
    20161 aagagcaaga tgaatcaaag aggcgaaaga gtcgggtaaa acgaggagat cttggagagc
    20221 cagcaacacc tgataaaaaa gaaaatgatg cgaagtcttc agattctagc gtaggtgaag
    20281 aaactcttcc aagcccatcc ctgaaaccag gaaaaaaggt agcagaagct gagaagaagg
    20341 ttgaagaagc tgagaaaaaa gccaaggatc aaaaagaaga agatcaccgt aactacccaa
    20401 ccattactta caaaacgctt gaacttgaaa ttgctgagtc cgatgtggaa gttaaaaaag
    20461 cggagcttga actagtaaaa gaggaagcta agggatctcg aaacgaggaa aaagttaagc
    20521 aagcaaaagc ggaagttgag agtaaaaaag ctgaggctac aaggttagaa aaaatcaaga
    20581 cagatcgtaa aaaagcagaa gaagaagcta aacgaaaagc agcagaagaa gataaagtta
    20641 aagaaaaacc agctgaacaa ccacaaccag cgccggctcc tcaaccagaa aaaccagctc
    20701 cagctccaaa accagagaat ccagctgaac aaccaaaagc agaaaaacca gctgatcaac
    20761 aagctgaaga agactatgct cgtagatcag aagaagaata taatcgcttg actcaacagc
    20821 aaccgccaaa aactgaaaaa ccagcacaac catctactcc aaaaacaggc tggaaacaag
    20881 aaaacggtat gtggtacttc tacaatact
//
LOCUS       DBEJJV010000035        20374 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.035, whole genome shotgun sequence.
ACCESSION   DBEJJV010000035 DBEJJV010000000
VERSION     DBEJJV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 20374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20374
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.035"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            65..607
                     /locus_tag="ACL3GT_001550"
     CDS             65..607
                     /locus_tag="ACL3GT_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HGR0517201.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDVIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSIDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(648..721)
                     /locus_tag="ACL3GT_001551"
     tRNA            complement(648..721)
                     /locus_tag="ACL3GT_001551"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(685..687),aa:Asn,seq:gtt)
     gene            complement(727..798)
                     /locus_tag="ACL3GT_001552"
     tRNA            complement(727..798)
                     /locus_tag="ACL3GT_001552"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(763..765),aa:Glu,seq:ttc)
     gene            complement(850..1602)
                     /gene="comE"
                     /locus_tag="ACL3GT_001553"
     CDS             complement(850..1602)
                     /gene="comE"
                     /locus_tag="ACL3GT_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system response regulator
                     transcription factor ComE"
                     /protein_id="HGR0517202.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(1599..2924)
                     /gene="comD"
                     /locus_tag="ACL3GT_001554"
     CDS             complement(1599..2924)
                     /gene="comD"
                     /locus_tag="ACL3GT_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence system sensor histidine kinase ComD"
                     /protein_id="HGR0517203.1"
                     /translation="MDLLGFGTVIVHFLIISHSYRLICKGRINRKELYIFGAYTLLTE
                     IVLEFSFYLLYLDKIGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     FKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVMVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            complement(2945..3070)
                     /gene="comC"
                     /locus_tag="ACL3GT_001555"
     CDS             complement(2945..3070)
                     /gene="comC"
                     /locus_tag="ACL3GT_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HGR0517204.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIKGGEMRISRIILDFLFLRKK"
     gene            complement(3235..3308)
                     /locus_tag="ACL3GT_001556"
     tRNA            complement(3235..3308)
                     /locus_tag="ACL3GT_001556"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3272..3274),aa:Arg,seq:tct)
     gene            complement(3352..3831)
                     /gene="rlmH"
                     /locus_tag="ACL3GT_001557"
     CDS             complement(3352..3831)
                     /gene="rlmH"
                     /locus_tag="ACL3GT_001557"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HGR0517205.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4014..5195
                     /locus_tag="ACL3GT_001558"
     CDS             4014..5195
                     /locus_tag="ACL3GT_001558"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1C family serine protease"
                     /protein_id="HGR0517206.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            5253..6011
                     /locus_tag="ACL3GT_001559"
     CDS             5253..6011
                     /locus_tag="ACL3GT_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HGR0517207.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            6224..7585
                     /gene="dnaA"
                     /locus_tag="ACL3GT_001560"
     CDS             6224..7585
                     /gene="dnaA"
                     /locus_tag="ACL3GT_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HGR0517208.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            7744..8880
                     /gene="dnaN"
                     /locus_tag="ACL3GT_001561"
     CDS             7744..8880
                     /gene="dnaN"
                     /locus_tag="ACL3GT_001561"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HGR0517209.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            8945..9139
                     /locus_tag="ACL3GT_001562"
     CDS             8945..9139
                     /locus_tag="ACL3GT_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HGR0517210.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEVTRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            9223..10338
                     /gene="ychF"
                     /locus_tag="ACL3GT_001563"
     CDS             9223..10338
                     /gene="ychF"
                     /locus_tag="ACL3GT_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HGR0517211.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            10410..10979
                     /gene="pth"
                     /locus_tag="ACL3GT_001564"
     CDS             10410..10979
                     /gene="pth"
                     /locus_tag="ACL3GT_001564"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HGR0517212.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSIDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            10980..14489
                     /gene="mfd"
                     /locus_tag="ACL3GT_001565"
     CDS             10980..14489
                     /gene="mfd"
                     /locus_tag="ACL3GT_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HGR0517213.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIVASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            14547..14813
                     /locus_tag="ACL3GT_001566"
     CDS             14547..14813
                     /locus_tag="ACL3GT_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HGR0517214.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            14806..15174
                     /locus_tag="ACL3GT_001567"
     CDS             14806..15174
                     /locus_tag="ACL3GT_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HGR0517215.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            15179..15301
                     /locus_tag="ACL3GT_001568"
     CDS             15179..15301
                     /locus_tag="ACL3GT_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0009 family protein"
                     /protein_id="HGR0517216.1"
                     /translation="MENLLDVIEQFLSLSDEKLEELADKNQLLRLQEEKERKNA"
     gene            15294..16562
                     /locus_tag="ACL3GT_001569"
     CDS             15294..16562
                     /locus_tag="ACL3GT_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HGR0517217.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFSIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            16559..17836
                     /gene="tilS"
                     /locus_tag="ACL3GT_001570"
     CDS             16559..17836
                     /gene="tilS"
                     /locus_tag="ACL3GT_001570"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HGR0517218.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            17840..18382
                     /gene="hpt"
                     /locus_tag="ACL3GT_001571"
     CDS             17840..18382
                     /gene="hpt"
                     /locus_tag="ACL3GT_001571"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HGR0517219.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            18398..20356
                     /gene="ftsH"
                     /locus_tag="ACL3GT_001572"
     CDS             18398..20356
                     /gene="ftsH"
                     /locus_tag="ACL3GT_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HGR0517220.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAHHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
BASE COUNT         7046 a         3298 c         3793 g         6237 t
ORIGIN      
        1 ctaaattaca agataaaaaa tctattttta gacatatagt ctaatttgtt tacaaggagg
       61 aaatatgcaa gaaagtaaca aacgcttaaa aacaaagcga actattgaaa atgctatggt
      121 acaattactg atggaacagc catttgataa aatttctact gtcaaattag tagaaaaagc
      181 cggaattagt cgttccagct tctatactca ctataaggat aagtatgatg tgattgagca
      241 ctatcaaagc aagctattcc atacatttga atatattttt caaaaacatg ctcatcacaa
      301 aagagacgct attttagaag tctttgaata tctagagtca gaaccacttc tggctgccct
      361 tctttctgaa aatgggacta aagaaatcca aaatttctta cgaaataaac ttcatatcat
      421 gctcagtata gatttacaaa agcgatttat gcaactgaat ctaaatacca ctgaattaga
      481 atatagtagc atctatctaa ctcatgcact ttttggtgtc tgccaaactt ggattgcaca
      541 tggaaaaaaa gaaagttctc aagaaataac agacttcctt atgaaaatgc ttggtgatac
      601 aaattgatac aaaaagagga acacagctgt gttccctttt atctatactc cgccagtagg
      661 actcgaacct acgacatcat gattaacagt catgcgctac taccaactga gctatggcgg
      721 ataaaatagt ccgtacggga ttcgaacccg tgttaccgcc gtgaaaaggc ggtgtcttaa
      781 ccccttgacc aacggacctt ctatctgtag cagatataac cattatatca atttcttgct
      841 aattgtcaat cacttttgag attttttctc taaaatatct tttaattttc taatttttaa
      901 tcttgaaata ggacaacgat ggtcttcata gaaaacaatt tctaagtttt ttcgatcaat
      961 ttctctgata ttgcctatat ttaccaaaaa tgacttgtga ggagaataaa atcgctgagt
     1021 atgtttgtcc ttttcctgaa tatctgtcat ggtaccataa aactcttttg caaaattctt
     1081 accaataatg cgcaatttat gagatacccc tgttgtttca atatacaaaa tatcatggta
     1141 aggaattttt aaatcatttc ccttgtaatt gtagtcgaaa taatctacaa catcttcatt
     1201 ttcaagtaac atactcttcg tgtagaagat attttgctca attctcttct taaacatctc
     1261 atcattgata tccttatcaa caaaatctag ggctgatacc tggtatttat aggttagagt
     1321 cgcaaactct gatcgactag tgataaagac aataatagcg taaggattgt aatgacgaat
     1381 gagctgagcc acttcaaatc cctttttctc aattccatga atatcgatat ctaggaaata
     1441 aagctgattt acttcatcat tttcaatgta ttcttcaaat tcacggactt ttcccgttgt
     1501 cttgtatgat attggaatat tcgattcttt cgaaatttca tccaatattc tctctagtct
     1561 cacttgatgt tcaataacat cttctaaaat taaaactttc attcaaattc cctcttaaat
     1621 ctaatgattt gtctaaatgt actgccttcc atctctgttt ctaaaataat attgttgtac
     1681 ttatctagta gttctttcac attatttaat ccgactccgc gatttcttcc cttagtggag
     1741 aatcctaagg caaatagatc tcctgaagga gtcatcgtca ttttacatga attctgaatc
     1801 accataactg tttcagtttc catcttaata actgctactt ccatctgctt tttatagcta
     1861 tcagccgatc cttcgacagc attattcaat aaaacgctca tgatacgaac caaatccaat
     1921 agttcaattg gaagcttggt aatcgtatct tttacttcca gtgtaaactc tacaccatta
     1981 tttcgagcat agacaattga ctgagcaacc aaacttcgta aagctgagtc ttctatgttg
     2041 ttcaaatcaa agtaagtgta cttatctgaa cgcaatttat gatttgcttt gactaaaact
     2101 tcattgtaaa ttctgtcaat ttcctgtaaa ttaccactgt caattgccat ctgcatgctg
     2161 acaagcattc cagcataatc atgtcgaaaa ccacggattt cattatacag accaacaatt
     2221 tcatctgtgt aattctgtaa atgtttctgt tcaaatttct tctgcttaaa agcaatctct
     2281 ttctccattt gaactttatg agaattcatt gcaaagaagg tcaaaaggag agagataaag
     2341 acaatagatg acaaaatact tccaaaacta ttcaaatgtt taatcgtact taccatatct
     2401 gaaacgaaag atacaatatg tagcaatagt aaagcaaaaa atactttttt caagaaagga
     2461 taaaggtagt ccttgtcaaa ataggctagt tccaaatgga aataataaat gatttttaat
     2521 gtaacaaaat aggttaacac cgtcacaacg aaaaagaatg ggaaatgata ttgtaaaaca
     2581 aaattatctc ctgttataga ggagaaagtt acggacagaa agttatgagt gctctcatat
     2641 aaaagagata gtagtaaact taggaatagt cctctatccc tctcatactg tttcatccat
     2701 cgaaaatagg aatataagcc caaaggaaat aaaaatcttt caatccctat tttatctaaa
     2761 tatagaagat aaaaggaaaa ttcaagtact atttcagtta gtaatgtata agcaccaaaa
     2821 atgtataatt cttttctatt tattcgacct ttacaaatta aacggtaact gtgactaata
     2881 attaaaaaat gaacaataac tgtcccaaat ccaagtaaat ccattactct ttctccttat
     2941 ttcattactt ttttcgtagg aaaagaaaat caaggatgat tcttgaaatc ctcatctccc
     3001 cacctttaat attttgtaag tctttttcct tcaaagctac aaactgttcc aatttaactg
     3061 tgtttttcat aataaaatct cctaaaatgt tttttcttgt aagctaactt acaaaaacca
     3121 ttatacaaaa tggaatttca ctttagataa aattctctca actgtcattt ttttctccca
     3181 aagtgtactt ttttaagaaa aaagccggga aaattcccag ctttgctatt atattgatcc
     3241 cagcaggatt cgaacctgcg accgttcgct tagaaggcga atgctctatc cagctgagct
     3301 atgagaccta acacaattat tctaccaaaa attcaattaa aagtcaattt tctatttatg
     3361 gtaggggaat ccctgctgaa tcgtaaaagc gcgatagatt tgttcaacaa gaactagtct
     3421 cattaactga tgaggcaagg ttaggcgacc aaaactgaca gaaagattgg ctctattttt
     3481 tacagatgat gacaatccta aacttccccc aataataaaa gtaagagtag aaaatccttt
     3541 tatagaagtt tcttctaact gcttactaaa ttcttctgag aagaaagttt tcccttcaat
     3601 ggctaacaca ataacgaaat cacggtcagc aatttttgat aaaattctct gaccttctat
     3661 ttctaaaatc ttttgatttt ctgattcact ggccttatct ggtgtttttt catctgataa
     3721 ctcaatcatt tcaaacttag caaatctaga aattcgtttt gaatactctg cgataccatc
     3781 ttttaaatac ttttctttca gtttcccaac tgttacaact ttaattttca tgactctatt
     3841 ctaacatatt ctctattttt tcacatctta ttcacaaaat aaaaaataga tttcaattaa
     3901 gaaaatcaca gtttcaaaag agttatccac agtttgtgta aaacttttgt gtttaagtta
     3961 taattaagct agtcagttta tactttcagt aattcaaaca tatggaggca aatatgaaac
     4021 atctaaaaac attttacaaa aaatggtttc aattattagt cgttatcgtc attagctttt
     4081 ttagtggagc cttgggtagt ttttcaataa ctcaactaac tcaaaaaagt agtgtaaaca
     4141 actctaacaa taatagtact attacacaaa ctgcctataa gaacgaaaat tcaacaacac
     4201 aggctgttaa caaagtaaaa gatgctgttg tttctgttat tacttattcg gcaaacagac
     4261 aaaatagcgt atttggcaat gatgatactg acacagattc tcagcgaatc tctagtgaag
     4321 gatctggagt tatttataaa aagaatgata aagaagctta catcgtcacc aacaatcacg
     4381 ttataaatgg cgccagcaaa gtagatattc gattgtcaga tgggactaaa gtacctggag
     4441 aaattgtcgg agctgacact ttctctgata ttgctgtcgt aaaaatctct tcagaaaaag
     4501 tgacaacagt agctgagttt ggtgattcta gtaagttaac tgtaggagaa actgctattg
     4561 ccatcggtag cccgttaggt tctgaatatg caaatactgt cactcaaggt atcgtatcca
     4621 gtctcaatag aaatgtatcc ttaaaatcgg aagatggaca agctatttct acaaaagcca
     4681 tccaaactga tactgctatt aacccaggta actctggcgg cccactgatc aatattcaag
     4741 ggcaggttat cggaattacc tcaagtaaaa ttgctacaaa tggaggaaca tctgtagaag
     4801 gtcttggttt cgcaattcct gcaaatgatg ctatcaatat tattgaacag ttagaaaaaa
     4861 acggaaaagt gacgcgtcca gctttgggaa tccagatggt taatttatct aatgtgagta
     4921 caagcgacat cagaagactc aatattccaa gtaatgttac atctggtgta gttgttcgtt
     4981 cggtacaaag taatatgcct gccaatggtc accttgaaaa atacgatgta attacaaaag
     5041 tagatgacaa agagattgct tcatcaacag acttacaaag tgctctttac aaccattcta
     5101 tcggagacac cattaagata acctactatc gtaacgggaa agaagaaact acctctatca
     5161 aacttaacaa gagttcaggt gatttagaat cttaattgac atctatgtaa agaaagcttt
     5221 acataagaga aaagatgtgt tagtgtagaa tcatggaaaa atttgaaatg atttctatca
     5281 cagatataca aaaaaatccc tatcaacccc gaaaagaatt tgatagagaa aagctagatg
     5341 aactagcaca gtctatcaaa gaaaatgggg tcattcaacc gattattgtt cgtcaatctc
     5401 ctgttattgg ttatgaaatc cttgcaggag agagacgcta tcgggcttca cttttagctg
     5461 gtctacggtc tatcccagct gttgttaaac agatttcaga ccaagagatg atggtccagt
     5521 ccattattga aaatttacag agagaaaatt taaacccaat agaagaagca cgcgcctatg
     5581 aatctctcgt agagaaagga ttcacccatg ctgaaattgc agataagatg ggcaagtctc
     5641 gtccatatat cagcaactcc attcgtttac tttccttgcc agaacagatt ctctcagaag
     5701 tagaaaatgg caaactatca caagcccatg cgcgttccct agttgggtta aataaggaac
     5761 aacaagacta tttctttcaa cggattatag aagaagatat ttctgtaagg aagttagaaa
     5821 ctcttctgac agagaaaaaa caaaagaaac agcaaaaaac taatcatttc atacaaaatg
     5881 aagaaaaaca gttaagaaaa ctactcggat tagatgtaga aattaaacta tctaaaaaag
     5941 acagtggaaa aatcattatt tctttttcaa atcaagaaga atatagtaga attatcaaca
     6001 gcctgaaata aggctgttct tttatttttt tatctcacaa ggttatccac tatgtttttc
     6061 gataaaaagc ttaataaatc aataatttct tcttttatcc ccaacctgtg gataaagttt
     6121 ggtaacattg tggattattt ttcacagctt gtggaaaatt cttgctatct atggtaaaat
     6181 atctctagta ttaaactttt aaatagtaaa ggaggagaaa ggattgaaag aaaaacaatt
     6241 ttggaatcgt atattagaat ttgcacaaga aagactgact cgatccatgt atgatttcta
     6301 tgctattcaa gctgaactca tcaaggtaga ggaaaatgtt gccactatat ttctacctcg
     6361 ctctgaaatg gaaatggtct gggaaaaaca actaaaagat attattgtag tagctggttt
     6421 tgaaatttat gacgctgaaa taactcccca ctatattttc accaaacctc aagatacgac
     6481 tagctcacaa gttgaagaag ctacaaattt aactctttat gactatagtc caaagttagt
     6541 atctattcct tattcagata cgggattaaa agaaaagtat acctttgata actttattca
     6601 aggggatgga aatgtttggg ctgtatcagc cgctttagct gtctctgaag atttggctct
     6661 gacctataac cctcttttta tctatggagg accaggcctt ggtaagactc acttattaaa
     6721 cgctattgga aatgaaattc taaaaaatat tcctaatgcg cgtgttaaat atatccctgc
     6781 cgaaagcttt attaatgact ttcttgatca cctaagactt ggggaaatgg aaaagtttaa
     6841 aaagacctat cgtagtcttg atcttttgtt aatcgatgat atacagtcac tcagcggaaa
     6901 aaaagtcgca actcaggaag aatttttcaa tacctttaac gcccttcatg acaagcaaaa
     6961 acagattgtc ctaacgagtg atcgtagtcc aaaacatcta gaagggctcg aggagaggct
     7021 tgtcacgcgt tttagttggg gattgacaca aactatcaca ccccctgact ttgaaacacg
     7081 tattgccatt ttacaaagta agacggaaca tttaggctac aatttccaaa gtgatactct
     7141 agaataccta gctgggcaat ttgattcaaa tgttcgagat cttgagggag ccatcaacga
     7201 catcacttta attgccagag taaaaaaaat caaggatatc actattgata ttgctgcaga
     7261 agccattaga gcccgcaaac aagatgttag ccaaatgctc gtcatcccaa ttgataaaat
     7321 ccaaactgaa gttggtaact tttatggtgt tagtatcaaa gaaatgaagg gaagtagacg
     7381 ccttcaaaat attgttttgg cccgtcaagt agccatgtat ttatctagag aactaacaga
     7441 taatagtctt ccaaaaattg ggaaggaatt tgggggaaaa gatcatacca cagtcattca
     7501 tgcccatgcc aaaataaaat ctttgattga tcaagacgat aatttacgtt tagaaattga
     7561 atcaatcaaa aagaaaatca aataatttgt ggataacttt tagtttttta tcttttttat
     7621 ccacattttt taaacaagct aaaaaacttg atatgacttg tttaaaggct gttttccaca
     7681 gatttcacag actctattat tactattatc tttctaatac taaaaataaa taaaggagaa
     7741 tccatgattc atttttcaat taataaaaat ttatttctac aagcattaaa tactactaag
     7801 agagctatta gttctaaaaa tgccattcct attttatcaa cagtaaaaat tgacgtgacc
     7861 aatgaaggta ttactttaat tggttcaaat ggtcaaattt caattgaaaa ttttatttct
     7921 caaaaaaatg aagatgctgg tttgttaatt acttctttag gttcgatcct tcttgaagct
     7981 tctttcttta tcaatgtagt atctagttta cctgatgtga ctcttgattt taaagaaatt
     8041 gaacaaaatc aaattgtttt aaccagtggc aaatcagaaa ttaccctaaa aggaaaagat
     8101 agcgaacaat atccacgaat ccaagaaatt tcagcaagca ctcctttaat acttgaaaca
     8161 aaattactca agaaaattat taatgaaaca gcctttgctg caagtacaca agagagtcgt
     8221 ccgattttaa caggtgtcca cttcgtattg agtcaacaca aagagttaaa aacagttgca
     8281 acagactctc atcgcctaag ccagaaaaaa ttgactcttg aaaaaaatag tgatgatttt
     8341 gatgtcgtaa ttcctagccg ttctctacgc gaattttcag cggtatttac agatgatatc
     8401 gaaactgtag agattttctt tgccaataac caaatcctct ttagaagcga aaatattagc
     8461 ttctatactc gtctcctaga aggaaactat cctgatacag atcgcttgat tccaacagac
     8521 tttaacacta ctattacttt taatgtggta aacttacgcc agtcaatgga gcgtgcccgt
     8581 cttttatcaa gtgcgactca aaatggtact gtgaaacttg aaattaagga tggggttgtt
     8641 agcgcccatg ttcactctcc agaagttggt aaagtaaacg aagaaatcga tactgatcag
     8701 gttactggtg aagatttgac cattagtttc aacccaactt acttgattga ttctcttaaa
     8761 gctttaaata gcgaaaaggt gaccattagc tttatctcag ctgttcgtcc atttactctt
     8821 gtgccagcag atactgacga agacttcatg cagctcatta caccagttcg tacaaattaa
     8881 gtgaaagagg ttgagcctgg ctcgcctctt ttatgatata atcgaaaaag aaaaggagag
     8941 tagtatgtat caagttggaa attttgttga gatgaaaaaa tcacacgctt gtacaatcaa
     9001 gtcgactggt aaaaaggcta atcgttggga agttacacgt gtaggagcag atatcaaaat
     9061 aaaatgcagt aattgtgagc atgttgtcat gatggggcga tatgattttg agcgaaaaat
     9121 gaataaaatt attgactgag aacccttagt tagagggtta gcactttatc cctttttgtg
     9181 ttataatatt agggattgaa atgaaaacgg agaatgagaa atatggcttt gacagcaggt
     9241 atcgttggtt tgccaaacgt tggtaaatca acattattta atgcaattac aaaagcagga
     9301 gcagaggcag caaactaccc atttgcgact attgatccaa atgttggaat ggtggaagtt
     9361 ccagatgaac gcctacaaaa actaactgaa atgataactc ctaaaaagac agttcccaca
     9421 acatttgaat ttacagatat tgcagggatt gtaaaaggag cttcaaaagg agaagggcta
     9481 gggaataaat tcttggccaa tattcgtgaa gtagatgcga ttgttcacgt agttcgtgct
     9541 tttgatgatg aaaatgtgat gcgcgagcaa ggacgtgaag acgcctttgt agatccactt
     9601 gcagatattg atacaattaa tctggaattg attcttgctg acttagaatc agtgaacaaa
     9661 cgatatgcgc gtgtagaaaa gatggcacgt acgcaaaaag ataaagaatc agtagcagaa
     9721 ttcaatgttc ttcaaaagat taaaccagtc ctagaagacg ggaaatcagc tcgtaccatt
     9781 gaatttacag atgaggaaca aaaggttgtc aaaggtcttt tccttttgac gactaaacca
     9841 gttctttatg tagctaatgt ggacgaggat gtggtttcag aacctgactc tatcgactat
     9901 gtcaaacaaa ttcgtgaatt tgcagcgaca gaaaatgctg aagtagtcgt tatttctgcg
     9961 cgtgctgagg aagaaatttc tgaattggat gatgaagata aaaaagagtt tcttgaagcc
    10021 attggtttga cagaatcagg tgtagataag ttgacgcgtg cagcttacca cttgcttgga
    10081 ttgggaactt acttcacagc tggtgaaaaa gaagttcgcg cttggacttt caaacgtggt
    10141 atgaaggctc ctcaagcagc tggtattatc cactcagact ttgaaaaagg ctttattcgt
    10201 gcagtaacca tgtcatatga agatctagtg aaatacggat ctgaaaaggc cgtaaaagaa
    10261 gctggacgct tgcgtgaaga aggaaaagaa tatatcgttc aagatggcga tatcatggaa
    10321 ttccgcttta atgtctaaaa attaataaat ggtgtcaatt aggttggaaa aaaaattcca
    10381 acccttttgg cttttgaaag gaaaaataaa tgaccaaatt acttgtaggc ttgggaaatc
    10441 caggggataa atattttgaa acaaaacaca atgttggttt tatgttgatt gatcaactag
    10501 cgaagaaaca gaatgtcact tttacacacg ataagatatt tcaagctgac ctagcatcct
    10561 ttttcctaaa tggagaaaaa atttatctgg ttaaaccaac gacctttatg aatgaaagtg
    10621 gaaaagcagt tcatgcttta ttaacttact atggtttgga tattgacgat ttacttatca
    10681 tttacgatga tcttgacatg gaagttggga aaattcgttt aagagcaaaa ggctcagcag
    10741 gtggtcataa tggtatcaag tctattattc aacatatagg aactcaggtc tttaaccgtg
    10801 ttaagattgg aattggaaga cctaaaaatg gtatgtcagt tgttcatcat gttttgagta
    10861 agtttgacag ggatgattat atcggtattt tacagtctat tgacaaagtt gacgattctg
    10921 taaactacta tttacaagag aaaaattttg agaaaacaat gcagaggtat aacggataaa
    10981 tggtgacctt attagattta ttctcagaaa atgatcagat taaaaaatgg catcaaaatt
    11041 taacagataa gaaaagacaa ctaatacttg gtttatcaac atctactaag gctcttgcaa
    11101 ttgcaagcag tttagaaaaa gaagatagga ttgtgttatt gacgtcaact tatggagaag
    11161 cagaaggact tgttagtgat cttatatcta tcttgggtga ggaactcgtc tatccatttt
    11221 tggtagatga tgctcctatg gtggagtttt tgatgtcttc acaggaaaaa attatttcac
    11281 gggttgaagc cttgcgtttt ttgactgatt catctaagaa agggatttta gtttgtaata
    11341 tcgtagcaag tcgattgatt ttaccgtctc ccaatgcatt caaagatagt attgtaaaaa
    11401 tctcagttgg tgaagaatat gatcaacacg cgtttatcca tcagttaaag gaaaatggct
    11461 atcgaaaagt tactcaagta caaactcagg gcgaatttag tcttcgagga gatattttag
    11521 atatttttga aatatcccag ttagaacctt gtcgaattga gttttttggt gatgaaattg
    11581 atggtatcag gtcatttgaa gtagaaacac aattatcgaa agaaaataag acagaactca
    11641 ctatctttcc agctagtgat atgcttttga gagaaaagga ttatcaacga ggacagtcag
    11701 ctttagaaaa acaaatttca aaaactttat cacctatttt gaaatcatac ctagaagaaa
    11761 ttctttcaag ttttcaccaa aaacaaagtc atgcagactc tcggaagttt ttatctttgt
    11821 gctatgataa gacatggact gtctttgatt atattgaaaa agatacccca atattctttg
    11881 atgattatca aaaattgatg aatcagtatg aagtctttga aagagactta gcgcagtact
    11941 ttacagaaga attacagaat agtaaagcat tttctgatat gcagtatttt tctgatattg
    12001 aacaaatcta taaaaaacaa agtccagtga cctttttctc taatcttcaa aagggtttag
    12061 gaaatctcaa atttgacaaa atttatcaat tcaatcaata tcctatgcag gaatttttca
    12121 atcagttttc ttttctaaaa gaagaaattg aacgatataa aaaaatggat tacaccatta
    12181 ttctgcagtc tagcaattca atgggaagta aaacattgga ggatatgtta gaggaatatc
    12241 agattaaatt ggattctaga gataagacaa atatctgtaa agaatctgta aacttaatag
    12301 agggtaatct cagacatggt tttcattttg tagatgaaaa gattttattg ataactgaac
    12361 atgagatttt tcaaaagaaa ttaaagcgtc gttttcgaag acaacatgtt tcaaatgcag
    12421 agagattaaa agattacaat gaacttgaaa aaggggacta tgttgtccat catatccatg
    12481 ggattggtca atatctagga attgaaacca ttgaaatcaa gggaattcat cgcgattatg
    12541 tcagtgtcca ataccaaaat ggtgatcaaa tttctatccc cgtggaacag attcatctac
    12601 tgtccaaata tatttcaagt gatggtaaag ctccaaaact caataaatta aatgacggtc
    12661 attttaaaaa ggccaagcaa aaggttaaga accaggtaga ggatatagct gatgatttaa
    12721 tcaaactcta ctctgaacgt agtcagttga agggttttgc tttctcagct gatgatgatg
    12781 atcaagatgc ctttgatgat gctttccctt atgttgaaac ggatgatcaa cttcgtagta
    12841 ttgaggaaat caagagggat atgcaggctt ctcagccaat ggatcgactt ttagttgggg
    12901 atgttggttt tggaaagact gaagttgcta tgcgtgcagc ctttaaagca gtcaatgatc
    12961 acaaacaggt tgtcattcta gttccgacga cggttttagc gcaacagcac tatacgaatt
    13021 ttaaggaacg attccaaaat tttgcagtta atattgatgt gttgagtcgc tttagaagta
    13081 aaaaagagca gactgcaaca cttgaaaaat tgaaaaacgg tcaagtcgat attttgattg
    13141 gaacacatcg tgttttgtca aaagatgttg tgtttgctga tttgggcttg atgattattg
    13201 atgaggaaca gcgatttggt gtcaagcata aggaaacttt gaaagaactg aagaaacaag
    13261 tggatgtcct aaccttgacc gctacgccaa tccctcgtac cctccatatg tctatgctgg
    13321 gaatcagaga tttatctgtt attgaaactc cgccgactaa tcgctatcct gttcagacct
    13381 atgttttgga aaagaatgat agtgtcattc gtgatgctgt cttgcgtgaa atggagcgtg
    13441 gaggtcaagt ttattatctt tacaacaaag ttgacacaat tgttcagaag gtttcagaat
    13501 tacaggagtt gattccggag gcttcgattg gatatgttca tggtcgaatg agtgaagtcc
    13561 agttggaaaa tactctatta gactttattg agggacaata cgatatcttg gtgacgacta
    13621 ctattattga gacaggggtg gacattccaa atgctaatac tttatttatt gaaaatgcgg
    13681 accatatggg cttgtcaacc ttatatcagt taagaggaag agtcggtcgt agtaatcgta
    13741 ttgcttatgc ttatctcatg tatcgtccag aaaaatcaat cagtgaagtc tctgaaaaga
    13801 gattagaagc gattaaagga tttacagaat tgggctctgg ctttaagatt gcaatgcgag
    13861 atctttcgat tcgtggagca ggaaatcttt taggaaaatc ccagtctggt ttcattgatt
    13921 ctgttggttt tgaattgtat tcgcagttat tagaggaagc tattgctaaa cgaaacggta
    13981 atgctaacgc taacacaaga accaaaggga atgctgagtt gattttgcaa attgatgcct
    14041 atcttcctga tacttatatt tctgatcaac gacataagat tgaaatttac aagaaaattc
    14101 gtcaaattga caaccgtgtc aattatgaag agttacaaga ggagttgata gaccgttttg
    14161 gagaataccc agatgtagta gcctatcttt tagagattgg tttggttaaa tcatacttgg
    14221 acaaggtctt tgttcaacgt gtggaaagaa aagataataa aattacaatt caatttgaaa
    14281 aagtcactca acggctgttt ttagctcaag attattttaa agctttatcc gtaacgaact
    14341 taaaagcagg catcgctgag aataagggat taatggagct tgtatttgat gtccaaaata
    14401 agaaagatta tgaaatttta gaaggtctgc tgatttttgg agaaagttta ttagagataa
    14461 aagagtttaa ggaagaaaat tccatttgat atttttcttc tataaaatag ataaaaatgg
    14521 tacaataata aattgaggta ataaggatga gattagataa atatttaaaa gtatcgcgaa
    14581 ttatcaagcg tcgtacagtc gcaaaggaag tagcagataa aggtagaatc aaggttaatg
    14641 gaatcttggc caaaagttca acggacttga aagttaatga ccaagttgaa attcgctttg
    14701 gcaataagtt gctgcttgta aaagtactag agatgaaaga tagtacaaaa aaagaagatg
    14761 cagcaggaat gtatgaaatt atcagtgaaa cacgggtaga agaaaatgtc taaaaatatt
    14821 gtacaattga ataattcttt tattcaaaat gaataccaac gtcgtcgcta cctgatgaaa
    14881 gaacgacaaa aacggaatcg ttttatggga ggggtattga ttttgattat gctattattt
    14941 atcttgccaa cttttaattt agcgcagagt tatcagcaat tactccaaag acgtcagcaa
    15001 ttagcagact tgcaaactca gtatcaaact ttgagtgatg aaaaggataa ggagacagca
    15061 tttgctacca agttgaaaga tgaagattat gctgctaaat atacacgagc gaagtactat
    15121 tattctaagt cgagggaaaa agtttatacg attcctgact tgcttcaaag gtgataaaat
    15181 ggaaaattta ttagacgtaa tagagcaatt tttgagtttg tcagatgaaa agctggaaga
    15241 attggctgat aaaaatcaat tattgcgttt acaagaagaa aaggaaagga agaatgcgta
    15301 aattcttaat tattttgttg ctaccaagtt ttttgaccat ttcaaaagtc gttagcacag
    15361 aaaaagaagt cgtctatact tcgaaagaaa tttattacct ttcacaatct gactttagta
    15421 tttattttag agaaaaatta agttctccca tggtttatgg agaggttcct gtttatgcga
    15481 atgaagattt agtagtggaa tctgggaaat tgactcccaa aacaagtttt caaataaccg
    15541 agtggcgctt aaataaacaa ggaattccag tatttaagct atcaaatcat caatttatag
    15601 ctgcggacaa acgattttta tatgatcaat cagaggtaac tccaacaata aaaaaagcat
    15661 ggttagaatc tgactttaaa ctgtacaata gtccttatga tttaaaagaa gtgaaatcat
    15721 ccttatcagc ttattcgcaa gtatcaatcg acaagaccat gtttgtagaa ggaagagaat
    15781 ttctacatat tgatcaggct ggatgggtag ctaaagaatc aacttctgaa gaagataatc
    15841 ggatgagtaa agttcaagaa atgttatctg aaaaatatca gaaagattct ttctctattt
    15901 atgttaagca actgactact ggaaaagaag ctggtatcaa tcaagatgaa aagatgtatg
    15961 cagccagcgt tttgaaactc tcctatctct attatacgca agaaaaaata aatgagggtc
    16021 tttatcagtt agatacgact gtaaaatacg tatctgcagt caatgatttt ccaggttctt
    16081 ataaaccaga gggaagtggt agtcttccta aaaaagaaga taataaagaa tattctttaa
    16141 aggatttaat tacgaaagta tcaaaagaat ctgataatgt agctcataat ctattgggat
    16201 attacatttc aaaccaatct gatgccacat tcaaatccaa gatgtctgcc attatgggag
    16261 atgattggga tccaaaagaa aaattgattt cttctaagat ggccgggaag tttatggaag
    16321 ctatttataa tcaaaatgga tttgtgctag agtctttgac taaaacagat tttgatagtc
    16381 agcgaattgc caaaggtgtt tctgttaaag tagctcataa aattggagat gcggatgaat
    16441 ttaagcatga tacgggtgtt gtctatgcag attctccatt tattctttct attttcacta
    16501 agaattctga ttatgatacg atttctaaga tagccaagga tgtttatgag gttctaaaat
    16561 gagggaacca gattttttaa atcattttct caagaaggga tatttcaaaa agcatgctaa
    16621 ggcggttcta gctctttctg gtggattaga ttccatgttt ctatttaagg tattgtctac
    16681 ttatcaaaaa gagttagaga ttgaattgat tctagctcat gtgaatcata agcagagaat
    16741 tgaatcagat tgggaagaaa aggaattaag gaagttggct gctgaagcag agcttcctat
    16801 ttatatcagc aatttttcag gagaattttc agaagcgcgt gcacgaaatt ttcgttatga
    16861 tttttttcaa gaggtcatga aaaagacagg tgcgacagct ttagtcactg cccaccatgc
    16921 tgatgatcag gtggaaacga ttttgatgcg cttgattcga ggaactcgct tgcgctatct
    16981 atcaggaatt aaggagaagc aagtagtcgg agagatagaa atcattcgtc ccttcttgca
    17041 ttttcagaaa aaagactttc catcaatttt tcactttgaa gatacatcaa atcaggagaa
    17101 tcattatttt cgaaatcgta ttcgaaattc ttacttacca gaattggaaa aagaaaatcc
    17161 tcgatttagg gatgcaatct taggcatcgg caatgaaatt ttagattatg atttggcaat
    17221 agctgaatta tctaacaata ttaatgtgga aaatttacag cagttatttt cttactctga
    17281 gtctacacaa agagttttac ttcaaactta tctgaatcgt tttccagatt tgaatcttac
    17341 aaaagctcag tttgctgaag ttcagcagat tttaaaatct aaaagccagt atcgtcatcc
    17401 gattaaaaat ggctatgaat tgataaaaga gtaccaacag tttcagattt gtaaaatcag
    17461 tccgcaggct gatgaagagg aagatgaact tgtgttacac tatcaaaatc aggtagctta
    17521 tcaaggatat ttattttcct ttggacttcc attagaaggt gaattaattc aacaaatacc
    17581 tgtttcacgt gaaacatcca tacacattcg tcatcgaaaa acaggagatg ttttgattca
    17641 aaatgggcat agaaaaaaac tcagacgttt atttattgat ttgaaaatcc ctatggaaaa
    17701 gagaaactct gctcttatta ttgagcaatt tggtgaaatt gtctcaattt tgggaattgc
    17761 gaccaataat ttgagtaaaa aaacgaaaaa tgatataatg aacactgtac tttatataga
    17821 aaaaatagat aggtaaaaaa tgttagaaaa cgatattaaa aaagtcctcg tttcacacga
    17881 tgaaattaca gaagcagcta aaaaactagg tgctcaatta actaaagact atgcaggaaa
    17941 aaatccaatc ttagttggga ttttaaaagg atctattcct tttatggctg aattggtcaa
    18001 acatattgat acacatattg aaatggactt catgatggtt tctagctacc atggtggaac
    18061 agcaagtagt ggtgttatca atattaaaca agatgtgact caagatatca aaggaagaca
    18121 tgttctattt gtagaagata tcattgatac aggtcaaact ttgaagaatt tgcgagatat
    18181 gtttaaagaa agagaagcag cttctgttaa aattgcaacc ttgttggata aaccagaagg
    18241 acgtgttgta gaaattgagg cagactatac ctgctttact atcccaaatg agtttgtagt
    18301 aggttatggt ttagactaca aagaaaatta tcgtaatctt ccttatattg gagtattgaa
    18361 agaggaagtg tattcaaatt agaaagaata atctttaatg aaaaaacaaa ataatggttt
    18421 aattaaaaat ccttttctat ggttattatt tatctttttc cttgtgacag gattccagta
    18481 tttctattct gggaataact caggaggaag tcagcaaatc aactatactg agttggtaca
    18541 agaaattacc gatggtaatg taaaagaatt aacttaccaa ccaaatggta gtgttatcga
    18601 agtttctggt gtctataaaa atcctaaaac aagtaaagaa ggaacaggta ttcagttttt
    18661 cacgccatct gttactaagg tagagaaatt taccagcact attcttcctg cagatactac
    18721 cgtatcagaa ttgcaaaaac ttgctactga ccataaagca gaagtaactg ttaagcatga
    18781 aagttcaagt ggtatatgga ttaatctact cgtatccatt gtgccatttg gaattctatt
    18841 cttcttccta ttctctatga tgggaaatat gggaggaggc aatggccgta atccaatgag
    18901 ttttggacgt agtaaggcta aagcagcaaa taaagaagat attaaagtaa gattttcaga
    18961 tgttgctgga gctgaggaag aaaaacaaga actagttgaa gttgttgagt tcttaaaaga
    19021 tccaaaacga ttcacaaaac ttggagcccg tattccagca ggtgttcttt tggagggacc
    19081 tccggggaca ggtaagactt tgcttgctaa ggcagtcgct ggagaagcag gtgttccatt
    19141 ctttagtatc tcaggttctg actttgtaga aatgtttgtc ggagttggag ctagtcgtgt
    19201 tcgctctctt tttgaggatg ccaaaaaagc agcaccagct atcatcttta tcgatgaaat
    19261 tgatgctgtt ggacgtcaac gtggagtcgg tctcggcgga ggtaatgacg aacgtgaaca
    19321 aaccttgaac caacttttga ttgagatgga tggttttgag ggaaatgaag ggattatcgt
    19381 catcgctgcg acaaaccgtt cagatgtact tgatcctgcc cttttgcgtc caggacgttt
    19441 tgatagaaaa gtattggttg gccgtcctga tgttaaaggt cgtgaagcaa tcttgaaagt
    19501 tcacgctaag aacaagcctt tagcagaaga tgttgatttg aaattagtgg ctcaacaaac
    19561 tccaggcttt gttggtgctg atttagagaa tgtcttgaat gaagcagctt tagttgctgc
    19621 tcgtcgcaat aaatcgataa ttgatgcttc agatattgat gaagcagaag atagagttat
    19681 tgctggacct tctaagaaag ataagacagt ttcacaaaaa gaacgagaat tggttgctca
    19741 ccatgaggca ggacatacca ttgttggtct agtcttgtcg aatgctcgcg ttgtccataa
    19801 ggttacaatt gtaccacgcg gccgtgcagg cggatacatg attgcacttc ctaaagagga
    19861 tcaaatgctt ctatctaaag aagatatgaa agagcaattg gctggcttaa tgggtggacg
    19921 tgtagctgaa gaaattatct ttaatgtcca aactacagga gcttcaaacg actttgaaca
    19981 agcgacacaa atggcacgtg caatggttac agagtacggt atgagtgaaa aacttggccc
    20041 agtacaatat gaaggaaacc atgctatgct tggtgcacag agtcctcaaa aatcaatttc
    20101 agaacaaaca gcttatgaaa ttgatgaaga ggttcgttca ttattaaatg aggcacgaaa
    20161 taaagctgct gaaattattc agtcaaatcg tgaaactcac aagttaattg cagaagcatt
    20221 attgaaatac gaaacattgg atagtacaca aattaaagct ctttacgaaa caggaaagat
    20281 gcctgaagca gtagaagagg aatctcatgc actatcctat gatgaagtaa agtcaaaaat
    20341 gaatgacgaa aaataaccct gagagaggct ggag
//
LOCUS       DBEJJV010000036        19741 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.036, whole genome shotgun sequence.
ACCESSION   DBEJJV010000036 DBEJJV010000000
VERSION     DBEJJV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 19741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.036"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            168..857
                     /locus_tag="ACL3GT_001573"
     CDS             168..857
                     /locus_tag="ACL3GT_001573"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HGR0517221.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPK
                     EIAQRFINVIK"
     gene            882..1799
                     /locus_tag="ACL3GT_001574"
     CDS             882..1799
                     /locus_tag="ACL3GT_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HGR0517222.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            1827..3368
                     /locus_tag="ACL3GT_001575"
     CDS             1827..3368
                     /locus_tag="ACL3GT_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HGR0517223.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAIAIVYSYTGGLKSVLWTDFIQGVVLISGVVVALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLAIATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGVTGL
                     ILAAIYAAAQSTVSTGLNSVATSWTLDIQDVISKNMSEDRRTKIAQFVSLAVGLFSIV
                     VSIIMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTENKVSAPKYTTIHDISEIKADSS
                     WEVRH"
     gene            3394..3852
                     /locus_tag="ACL3GT_001576"
     CDS             3394..3852
                     /locus_tag="ACL3GT_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HGR0517224.1"
                     /translation="MIISEQSDFRRYASVNKHFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            3854..6076
                     /locus_tag="ACL3GT_001577"
     CDS             3854..6076
                     /locus_tag="ACL3GT_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004308 - exo-alpha-sialidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sialidase domain-containing protein"
                     /protein_id="HGR0517225.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTSISEVQHKSGNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVTRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPAPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIREHGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTQVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQISIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6116..7225
                     /locus_tag="ACL3GT_001578"
     CDS             6116..7225
                     /locus_tag="ACL3GT_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HGR0517226.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            7382..8272
                     /locus_tag="ACL3GT_001579"
     CDS             7382..8272
                     /locus_tag="ACL3GT_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0517227.1"
                     /translation="MKIIGIDIGGTTIKADLYDDFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYVLNYSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTSEIEKRF
                     GLSTFVENDVNCAALGELWEGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLSSGDKVAKETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNVVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            8297..8620
                     /locus_tag="ACL3GT_001580"
     CDS             8297..8620
                     /locus_tag="ACL3GT_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517228.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELISIESNLEMKQQNLIDEVNKTIKENDAKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            8610..10601
                     /locus_tag="ACL3GT_001581"
     CDS             8610..10601
                     /locus_tag="ACL3GT_001581"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HGR0517229.1"
                     /translation="MAISQMKRISLLFTKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFSTIQISHTSNSHHGVIEGNDALNYLMNKQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERNIQSNNEEIERLIKW
                     EKLEIIPAHLEQFSFCRGKVGTIPRTVDNRLYNNFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETRILYFIKVMDERFGHSIYIYE
                     SETLSDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGIMLALKIFHLPSVTKKFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ITTTSDVMTILVVSVVFGFITVFVGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDIRPLFVLGKWVSIFNAVGILIASIIQAKSLSGIGSGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGTLAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            10617..11093
                     /locus_tag="ACL3GT_001582"
     CDS             10617..11093
                     /locus_tag="ACL3GT_001582"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HGR0517230.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11127..11708
                     /locus_tag="ACL3GT_001583"
     CDS             11127..11708
                     /locus_tag="ACL3GT_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517231.1"
                     /translation="MSNLENLRESVIEQAHEKGSMKLLDSKKKIDDEFEMQKSVIVKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            11773..12780
                     /locus_tag="ACL3GT_001584"
     CDS             11773..12780
                     /locus_tag="ACL3GT_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HGR0517232.1"
                     /translation="MDTNLFSKINTTISVKENDFITEEKFQKIIQSKDTETLAFILEA
                     TPYHLSIDVLENPSQTEISLMTKLVNDYRWAYAESPSDKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELGEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKTLDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYG
                     S"
     gene            12770..13090
                     /locus_tag="ACL3GT_001585"
     CDS             12770..13090
                     /locus_tag="ACL3GT_001585"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HGR0517233.1"
                     /translation="MEANKYKIGIIGSHDIILPFSMIGFDIFSAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            13153..14928
                     /locus_tag="ACL3GT_001586"
     CDS             13153..14928
                     /locus_tag="ACL3GT_001586"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HGR0517234.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     AFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            14929..16314
                     /locus_tag="ACL3GT_001587"
     CDS             14929..16314
                     /locus_tag="ACL3GT_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HGR0517235.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            16337..16948
                     /locus_tag="ACL3GT_001588"
     CDS             16337..16948
                     /locus_tag="ACL3GT_001588"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HGR0517236.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            17221..17406
                     /locus_tag="ACL3GT_001589"
     CDS             17221..17406
                     /locus_tag="ACL3GT_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517237.1"
                     /translation="MPQPIVPVEIPQSRRFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            17387..17710
                     /gene="tnpB"
                     /locus_tag="ACL3GT_001590"
     CDS             17387..17710
                     /gene="tnpB"
                     /locus_tag="ACL3GT_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0517238.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
     gene            complement(17865..18173)
                     /locus_tag="ACL3GT_001591"
                     /pseudo
     CDS             complement(17865..18173)
                     /locus_tag="ACL3GT_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            18155..18592
                     /locus_tag="ACL3GT_001592"
                     /pseudo
     CDS             18155..18592
                     /locus_tag="ACL3GT_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            18699..19357
                     /locus_tag="ACL3GT_001593"
                     /pseudo
     CDS             18699..19357
                     /locus_tag="ACL3GT_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_050084071.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            19450..>19741
                     /locus_tag="ACL3GT_001594"
     CDS             19450..>19741
                     /locus_tag="ACL3GT_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HGR0517239.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAAVFGIHESNLIRRSQWVEVTLVQSG"
BASE COUNT         6529 a         2919 c         3980 g         6313 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa ccaattatta atggctgata tttctacttt tgaagaaggg aaagtagctg
      601 ctgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccaaa agaaattgct cagcgattta
      841 ttaatgtcat caaataaaaa acaatataaa ggagaaatct gatgaaagat ttaactaaat
      901 acaaaggcgt tattcctgca ttttatgctt gctatgatga aaatggtgaa attagccaag
      961 aacgtgtaaa atctctggtg caatatttca ttgacaaagg tgtaaaaggt atctatgtaa
     1021 atggttcttc aggtgaatgt atttaccaaa gtgtagaaga tcgtaaacaa attattgaag
     1081 ctgttatgga agttgctaaa ggtaaattaa cagttatcaa ccatgttgca tgtaataaca
     1141 cgaaagatag tattgaattg gcaaaacatt cagaaagtgt tggagtcgat gctattgctg
     1201 ctatcccacc tatttacttc aaattgccag aatattcaat tgcagcatat tggaatgcaa
     1261 tgagtgaagc tgcgccaaat acagatttta tcatttataa tattccacaa ttggcagggg
     1321 ttgcgttgac tggtagtttg tatgcaacaa tgcgtcaaaa tcctcgtgtg attggagtta
     1381 aaaattcttc tatgcctgta caagatattc aaatgtttgt agctgcaggt ggagaagatt
     1441 acattgtatt caatggtcca gatgaacaat atcttggtgg tcgcttgatg ggagcagaag
     1501 ctggtattgg tggtacttat ggcgttatgc cagatttgtt cttgaaattg gaaagtttga
     1561 ttcaagaacg agatttagat actgctaaaa aacttcaata tgctatcaat gaagttatct
     1621 ataagatgat atcaggtaag gcaaatatgt atgctgtagc aaaagaggtt ttgcgtctaa
     1681 atgaaaaact tgatttaggt tctgttcgtc aacccttaga agcattggca gaaggtgact
     1741 tggaagttgc aaaacaagca gcagaactta ttcaacaagc acgaaaagaa tttttataat
     1801 aaataaaatc aatatggaga tatgttatgg gcacaacagg atttacaata attgacttaa
     1861 ttatcttgat tgtttattta cttgcggtgt tggttgcagg tatctatttc tctaaaaaag
     1921 agatgaaagg aaaagagttc tttaaaggag atggttcggt tccttggtat gttacttcgg
     1981 tatccatttt tgccacaatg ctcagtccga tttccttctt gggactcgct ggtaactctt
     2041 atgcaggtag ctggatttta tggtttgctc aattagggat ggttgtagct attccactga
     2101 caattcgttt tatcttacct atctttgcac ggatagacat cgatacggca tatgattact
     2161 tggataaacg ttttaattct aaagcacttc gtattatttc agcactcttg tttattattt
     2221 atcaattggg acgtatgtct atcattatgt acctcccatc agctggttta tcagtattga
     2281 caggaattga catcaatatt ttgattattt tgatgggtgc aattgcaatt gtttattctt
     2341 atactggtgg tctaaaatcc gtattatgga cagactttat tcaaggtgtg gttctgatta
     2401 gtggtgtcgt tgtagcttta tttgtactga tggctaatat taaaggtggc tttggtgcag
     2461 tagcagaaac attagcaaac gggaaattcc ttgctgcaaa tgaaaaactt ttcgatccta
     2521 acttgctttc aaactccatc ttcttaattg tgatgggttc aggctttaca atcttgtctt
     2581 cctatgcttc atctcaagat ttggttcaac gttttactac aacacaaaat attaagaaac
     2641 ttaataaaat gttgttcaca aatggtgtct tgtcacttgc aattgcaaca gtcttttact
     2701 tgatcggtac aggcttgtac gtattctatc aagtacaaaa tgcaggtagt gcagctagca
     2761 atatccctca agaccaaatc tttatgtact ttattgcata ccagttacca gtaggtgtca
     2821 caggtttgat cttggcagcg atttatgcag cagctcaatc aactgtttca acaggtttga
     2881 actctgttgc aacttcatgg acattggata ttcaagatgt catttctaaa aatatgtcag
     2941 aggatcgtcg tacgaaaatt gcacaattcg tatctctagc agtaggttta ttctcaattg
     3001 ttgtttccat tatcatggct cattcagata ttaaatctgc atacgaatgg ttcaatagtt
     3061 tcatgggact tgtacttggt ctacttggtg gtgtattcat tcttggtttt gtttctaaaa
     3121 aagcaaataa acaaggtgct tatgcagcgc tgattgtatc aaccatcgtt atggtattta
     3181 ttaaatactt ccttcctcca acagctgtta gctactgggc atattcattg atttcaattt
     3241 ctgtatcagt agtttcaggt tatattgtat ctgttcttac tgaaaataaa gtatctgcac
     3301 ctaaatatac aacgattcat gatatttcag aaattaaagc ggattcaagt tgggaagttc
     3361 gtcactagtc actaatagaa aagagaaaat aatatgatta tttctgaaca atctgatttt
     3421 agacgatatg cttctgtcaa taaacatttt tcaaaagtct gtgatttttt agaaaataca
     3481 aatttgacag atttagttga tggaaaaatt gatattgacg gggaaaatgt ttttgcaaat
     3541 tgtatgactt atctagctga tggagttcca ggagatattt ttgaaactca taagaaatat
     3601 ttagatattc atattgttgt tgaaaataca gaaaaaatgg cagtaacttc cccagttcgt
     3661 gctcagtcac gtgtaccttt tagcgaagag aaggatattg ctttttacga tagcaaagac
     3721 tatcaaattg ttgaattgct tccagggaat atgttggtga cttttgaaga agatcttcac
     3781 caaccaaaga ttcattgcaa tgatgaaact gttaaaaaac ttgttatcaa agttttaaac
     3841 gaggaaaaat aaaatgaaaa aaaatattaa acaatatgta accttaggta ctgtagtggt
     3901 attatcagca tttgttgcta actcagttgc agctcaggag actgaaactt ctgaagtatc
     3961 aacaccagag ttggtgcaac ctgttgcacc aacgacttcg atttcggaag tacaacataa
     4021 atcgggtaac tcttcggaag ttactgtaca acctcgaaca gttgaaacta ctgttaagga
     4081 tccatcttct acagcggaag aaactcctgt cttagaaaaa aataatgtta ctttaacagg
     4141 gggcggagaa aatgttacta atgagttaaa ggataaattt actagcggtg actttactgt
     4201 agtgattaag tacaatcagt ctagtgagaa aggtttacaa gctctgtttg gaatatctaa
     4261 ttctaaaccc ggtcaacaaa atagttatgt agatgtgttc cttagagaca atggtgaatt
     4321 gggaatggaa gcgcgtgata cttcttccaa taaaaatcac ctagtaacca gacctgcttc
     4381 agtttggggt aagtacaaac aagaggccgt gacgaacact gttgcagtag tagcagattc
     4441 agtcaaaaaa acgtattctt tatatgcaaa tggtacaaaa gtagtagaaa agaaagtgga
     4501 taacttccta aacatcaagg atattaaagg tattgattac tatatgcttg ggggagtgaa
     4561 acgtgcagga aaaacggcgt ttggttttaa cggaacacta gaaaatatca aattctttaa
     4621 tagtgcattg gatgaagaaa ctgttaaaaa gatgacaaca aacgctgtta ctggacattt
     4681 aatttatacg gctaatgata caacaggttc taactatttc cgtattccag ttctgtatac
     4741 ttttagcaat ggtcgggttt tttcaagcat tgacgctcgt tacggtggaa ctcatgattt
     4801 cttgaataaa attaatattg ctacaagtta tagtgatgat aatggtaaga catggactaa
     4861 accaaaatta acattagcat tcgatgattt tgcgccagca ccattagaat ggcctcgtga
     4921 tgttggtgga cgtgacttac aaatcagcgg tggtgcaacc tatattgact ctgttattgt
     4981 tgaaaaaaat aacaaacaag tactcatgtt tgctgatgtt atgcctgctg gagtaagttt
     5041 tagagaagct actagaaaag attcaggtta taaacaaatt gatggtaatt attaccttaa
     5101 attaaagaaa caaggtgata ctgattataa ttatactatt cgtgagcatg gtactgtata
     5161 cgacgatcgt accaacagac caactgaatt ttcagtagat aaaaatttcg gtattaaaca
     5221 aaatggtaat tatttgacgg tagagcaata ttcggtttca tttgaaaata ataaaaagac
     5281 tgaatatcgt aatgggactc aagtccatat gaatatcttc tacaaagatg cattattcaa
     5341 agtagtgcca acgaactata ttgcatatat ttctagcaat gatcatggcg aatcttggtc
     5401 tgcaccaact ttattacctc ctataatggg acttaatcgg aatgcgcctt atttgggtcc
     5461 tggacgtgga atcattgaaa gctcaactgg acgtattctt attccgtctt acactggtaa
     5521 agagtctgca ttcatttata gtgacgataa tggagcgtct tggaaagtta aagttgtgcc
     5581 acttccttct agttggtcag cagaagcaca atttgtagaa ttgagtccag gagtaattca
     5641 agcatacatg cgtacaaata atggtaaaat tgcatattta acaagtaaag atgcaggtac
     5701 tacttggagt gcgccggaat atttgaaatt tgtttcaaat ccaagttatg gaacacaatt
     5761 atcaatcatc aattatagtc aattgattga tggtaaaaag gctgtcattt taagtactcc
     5821 aaactccaca aatggtcgta aacacggaca aatttcgatt ggtctaatta atgatgataa
     5881 tacaattgat tggcgttatc atcacgatgt tgattatagt aactatggat actcatattc
     5941 aacattgaca gagttaccaa atcatgaaat tggattgatg tttgaaaaat ttgattcatg
     6001 gtctcgtaat gaacttcata tgaaaaatgt tgtaccatat ataacattta agattgaaga
     6061 tttgaaaaag aattaaagct gaaatttaaa aatatataga aagaggataa aaattatggt
     6121 aaattacggt attgttggag ctggatattt tggagctgat ttggctcgct caatgaacaa
     6181 aattgaagat gcaaaagtgg ttgcggtatt tgacccaaat catggagaag aagttgctca
     6241 agagttggga tcagatgttt gtgcaagttt agatgaactt gtagcacgtg aagatattga
     6301 ttgtgtgatc gtagcttcac ctagctacct tcaccgtgaa cctgttgtga aagctgctca
     6361 acatggcaaa cacgtatttt gtgaaaagcc aattgcattg tcttatgaag attgtaaagc
     6421 catggttgac gcatgtaaag aaaataatgt tatctttatg gctggtcaca tcatgaactt
     6481 ctttaatggt gtacaccatg ctaaagaatt gattactcaa ggtaaaatcg gtaaagttct
     6541 ttattgccat gccgctcgta caggttggga agaacaacaa ccaactgtat catggaagaa
     6601 acttcgttct caatctggag gacatttgta ccaccatatt catgaattag attgcattca
     6661 gttcatcatg ggaggacttc ctgaaaaagc gacaatggta ggaggcaatg tatatcataa
     6721 aggtgaaaac tttggtgatg aagatgatat gctcattgta aacctagaat actctgatga
     6781 tcgttatgct gttttggaat atggtaatgc tttccgttgg ggtgaacact acgtcttgat
     6841 tcaaggaact gaaggagcta tcaaacttga cttgttcaat actggaggta ctcttcgtgt
     6901 taaaggtgaa ggagaatcac acttcttagt acatgaaact caagaggaag atgatgaccg
     6961 tacagctatc tataccggtc gtggtatgga tggagcaatt gcgtacggta aaccaggagt
     7021 acgttgccca ttatggttac aaacatgtat tgataaagaa atggaatatc tacatgacat
     7081 cattaaaggt ggagaaatta cagaagaata tgaaaaactt ctcaatggtg tagctgcttt
     7141 agaatcaatc gctaccgctg atgcatgtac tttatcagtt aaagaagatc gaaaagtaag
     7201 tctttcagaa atcacaaatg cttaactatt gtaaaacaga atagtaaatt cttgtcatta
     7261 tataatttct aaagttctgt gatacaactc attgaataaa gaaatagaga tgggactggg
     7321 ataatgccca gtcccatttt ttatcaaaaa gtaatgagat caaaaatgtg ggagtgatga
     7381 aatgaagatt atagggatcg atattggcgg aacaacaatt aaggcagatt tatacgatga
     7441 ttttggaacg agtttaaatc agttcaaaga gatagaaaca attattgact atgatttggg
     7501 aacgaaccag atattaaatc aggtctgtga tttaattggt gagtatgttt taaattattc
     7561 aattgatggt gttgggattt ccactgctgg agttgttaat gctaatacag gagaaatcat
     7621 ctatgcaggc tatacaatac cagggtatat cggagtaaac tttacttccg aaatagaaaa
     7681 acgttttggg ttgtctactt ttgttgaaaa tgatgttaat tgtgctgcat taggtgaatt
     7741 gtgggaggga caagccaaag ataagaaaaa tgtagtaatg gttactattg gaacaggtat
     7801 aggaggcagt attattgtca atggacaaat tgttaacgga tttaactata ctgctggtga
     7861 agtaggctat attcctgtag gtaattcgga ttggcaaagc aaagcctcaa caaccgcatt
     7921 gattcattta tatcaaaaga agagcttgaa aactaatcaa actggacgta ctttctttac
     7981 tgatttaagt tctggagata aagtcgctaa agaaactttt gaaatttttg tagaaaatct
     8041 aacaaaaggt ttattaacta tttcttatct acttaatcca gaaattctca tattaggagg
     8101 tgggattctg gctaaaaagg atattttgtt acctgaaatt caaagttctt tagctaaaaa
     8161 tgcaatggat aataggtttt tgcctaaaaa tgttgtggca gctacattag gaaatgaagc
     8221 tggtcgtata ggagctgtaa aaaatttctt agatagaatt tctaataaat agtgtgaaag
     8281 ataaggaggt gtcacaatga ctaactctgt attttcgaca atgcaagata ttgagaatgt
     8341 tgcaaccgat attataaaat catatgataa tgagatttat acgtataaag ctgtctccca
     8401 agaagaattg gaaaaactag aaaaaagtta tgatgaaaaa agtcacgaag aattaatttc
     8461 aatagaaagc aatttagaaa tgaaacaaca gaacctcatt gatgaggtta ataaaacaat
     8521 caaggaaaat gatgcaaaga ttcagtatat ttcatcaagt aggagaggag aatttgtaga
     8581 aaaaattatt ggtagggtgg tagaaaaata tggctattag tcagatgaaa agaatttctc
     8641 tactatttac taagagtagt cttgatgatg ttttaaaaac tattcaagaa ctagagtcag
     8701 tgcagttccg tgatttaaag gttcaggata actggtcaga agcgctagaa aaagatgagg
     8761 ttgtattttc aactattcaa atttctcaca cttctaattc ccatcatggg gttattgaag
     8821 gaaatgatgc cttgaattat ttgatgaata aacaacaaca tttggaagca actgtagaga
     8881 aattacaaga atacctaccg aaagaaaaca cgtttaagtt attacagcaa cctccgataa
     8941 caacctctta tgaagaatta gaaaaatttg gtaaagctaa tgttgctgag ggtgttctta
     9001 aaaaagtgaa tcatcaaata aacagagttc atgaattaga aagaaacatt caaagtaata
     9061 atgaggaaat agagagatta ataaagtggg aaaaattaga aattattcct gcgcatttag
     9121 aacaattttc tttctgtaga ggaaaagtcg gaacaattcc aaggactgta gataatcgct
     9181 tatacaataa ttttttagaa aacaatattg aagttcaaga aatattttct aatgatagag
     9241 agtacggtgt tgttgttttc tatcagtcca gttgctctat tgattttgat gaatacttat
     9301 ttgaaccatt tgattattct agaaaggaat taccgaagca gcgagtagta gatttggatc
     9361 aagaaaacat gcagttaata actgaaaaag agaatattat cgcatcgttg caagattcaa
     9421 agaaaaattt gatagattta caatggcaaa ttgactatat tttatctatc tatgctcgtc
     9481 aaatctctaa gaataacctt ttgagcactc cgcatctagt tgcattagaa ggatggatag
     9541 aagaaactcg tattttatat tttataaaag ttatggatga gcgttttgga cattctattt
     9601 atatttatga atcggaaaca ttgtcggata atcaagatga aatacctatc aaattaacga
     9661 atcactcttt aattgaacca tttgaattat tgacagaaat gtatgctctg cccaaatatt
     9721 atgagaaaga tcctacacct gtattagcac cattttactt tacatttttt ggaatgatgg
     9781 ttgctgattt aggctatggt ttactattgt ttttaggaat aatgttagca ttaaaaattt
     9841 ttcatctacc ttcagtaact aagaaatttt taaaattctt taatatatta ggggtagccg
     9901 ttgcaatttg gggtggaatc tatggctcat tttttggata tgagttgcca tttcatctga
     9961 taactacaac ctcggatgtc atgactatat tagtagtgtc agttgtgttt ggatttatta
    10021 cagtatttgt aggtttgtta gcttcaggac tacaaaaagt aagaatgaag aaatatgcag
    10081 aagcatataa ttcaggattt gcgtggtgtg ttattctgct tggcttgtta tttattgctg
    10141 tcggaatgtt gatgcctgat attagaccgt tatttgtatt agggaaatgg gtatctattt
    10201 ttaatgctgt ggggattttg attgcttcta ttattcaagc caaaagcttg tcaggtattg
    10261 gctcaggatt gtttaatcta tataacattt catcttatat aggtgattta gttagtttca
    10321 ctcgattgat ggcattagga ttatctggag caagtatagc atcagctttc aatttaattg
    10381 ttggtttgtt tccggggaca ttggctaaac tgacaattgg attagtatta ttcattcttt
    10441 tacatgcgat caatattttt ctatcgttac tatcaggata tgttcatgga gcgcgtctga
    10501 tatttgttga attttttggt aagttttatg agggtggagg aaaaccattt caacctttga
    10561 aggcttctga gaaatatatt aaggttatta caaagaatta atggaggata tatataatgg
    10621 aacatttagc aacttatttt tcaacctatg gaggagcttt cttcgctgca ttgggaattg
    10681 tattggcggt tggattaagc ggtatggggt ctgcttatgg agttggtaag gctgggcaat
    10741 ctgccgcagc tttactgaaa gaacagccag aaaaatttgc ctcagctttg atattgcaac
    10801 tattgcccgg aacacaagga ttatatggtt ttgttattgg aattttgatt tggttgcaat
    10861 taactccaga acttcctttg gaaaaaggcg ttgcttattt ctttgtagct cttccaattg
    10921 ctattgtagg atacttttcg gctaagcatc aaggaaatgt agcagtagcg ggaatgcaaa
    10981 tcttggctaa aagaccaaaa gaattcatga agggagcaat tttggctgcc atggtagaaa
    11041 cctatgcaat tcttgccttt gtcgtatcat tcattttgac ccttcgtgta taagaaatta
    11101 atttgctatt caaaggaggt gtctaaatga gcaatttaga aaacttacga gaatctgtta
    11161 ttgaacaagc tcatgaaaaa gggagtatga aattattgga ttccaaaaag aagattgatg
    11221 atgaatttga aatgcaaaag tcggtcattg taaagaaaaa agaagctgaa catgaacgaa
    11281 agttaaaaga attacaacag aaatatcaaa taatttttca acaattaaaa aataaggaac
    11341 gccaatcaac gttagtatca aaacagaaaa tattaaaaga actttttcaa tctgctttaa
    11401 tagaaatgga atcttggagt gcagataaag aaatggagtt catctatcga attctggaac
    11461 gatattcaca acaagaggtc atagtaactt ttggggagcg gactttagct aaattcaatt
    11521 tggaacaatt agagaaattg aaattctctt ttccaaatca tttatttagt gaacagccta
    11581 tctcaaatga atcaggctta cttatttcaa taggtaaaat tgatgataac tatttgtata
    11641 aaacgttaat tggatcgatt tctaaggaag aaagttcaag tatcgcaaat caaattttta
    11701 tcaattaagg atgaaattgg ttaatccttc ttagaaattt ggagtattcc aataaaatta
    11761 gaaaggtatt ttatggatac taatcttttt tcaaaaataa atacgacgat ttcggtaaaa
    11821 gaaaacgatt ttattacaga agaaaaattt caaaaaatta tacaatccaa agatacggag
    11881 acattggcat ttatcttaga agcaactccc tatcatttat cgattgacgt tttagaaaat
    11941 cctagtcaga cagagatttc gctaatgaca aaattagtca atgattatag atgggcctat
    12001 gctgaaagtc cgtctgataa aattgtgact ttatttgctt tacgatatgt ttatcataat
    12061 atcaaagttt tattaaaatc taaggcggca attaagaaag atttttctaa attattaatt
    12121 ccaataggga tttttgatat agaaagttta aaacatttag tttcttcctt acattcagat
    12181 acacttcctg attttatggt tcatgaagta gaatcaattt ggaatgagta tgaaactttt
    12241 aataatattc gtgtacttga tgtcggagct gatctagcat attttaaaca tctgaaactt
    12301 ttatctaatg agttaggtga ggtgctgtct caggttattg ttgcaatgat tgacttttat
    12361 aatattatta ctgtaaaacg tggtttatct caaaataaga gtcatgggga tattttacaa
    12421 ttactttcag atgaaggaag tatttctgct aaagaattta tatacattgt agaaaatcaa
    12481 gaaatatttg tgtggttcaa taaaataaat ccaagcttag attcaatctt ttcaacttac
    12541 gaattgaaga tgcaggacgc aacaatttca tcttctgagt tagaattttt atgtgattta
    12601 ctattgtata aaactttaga tcaaggaagg tataatgtag atgggccgtt agttcttgct
    12661 agatatttat tgggatgtga gtttgaagta aagaatctta gaatgatcat atcagctctt
    12721 caaaatacaa ttccttttga atcaataaaa gaaaggatac gcccgcatta tggaagctaa
    12781 taagtataaa attggcataa ttggtagcca tgatattatt ttacccttta gcatgattgg
    12841 gtttgatata ttttctgcct atcaagaaca agaagctata aatactctaa gaaaattagc
    12901 tcaatctgat tatggtgtca tttatatcac tgaagacatt gcttcaatga tattagatac
    12961 aattcgccat tatgattctc aagttgtgcc tgctattatt ttattaccga ctcataaaca
    13021 aggtttaaat ttaggattaa aacgtataga ggataatgta gagaaagcag taggacacaa
    13081 tattttataa taatgtacaa aattgtctgt aatattattc tataattttt ggacttagta
    13141 aggagaataa ctttgactca agggaagatt ataaaagtat cgggacctct agttattgca
    13201 tcaggtatgc aggaggctaa tattcaagat atttgccgtg taggtaagct agggttaatc
    13261 ggtgaaatta ttgaaatgag aagagatcag gcatctatcc aagtctatga agaaacatct
    13321 ggtcttggtc cgggagaacc tgttgttaca actggagaac ctctctcggt tgaattaggg
    13381 ccaggattga tttctcaaat gtttgatggc atacaacgcc cattagatcg atttaaattg
    13441 gctactcata atgattttct agttcgtggg gtagaagttc caagtttgga tagagatatt
    13501 aagtggcatt ttgattccac tatagcaatt ggtcaaaaag tgagtacggg tgatattctt
    13561 ggaactgtca aggaaaccga ggtagttaat cataaaatta tggttcctta tggagtatct
    13621 ggagaagtcg tttctattgc atctggcgat tttacaattg atgaagttgt atatgaaata
    13681 aaaaaattgg acggtagttt ctataaagga acgcttatgc aaaaatggcc tgtccgcaag
    13741 gcgcgtcctg tttctaaacg tttaattcca gaagaaccat taatcacagg tcaacgagtt
    13801 attgatgcat tctttccagt aaccaaaggg ggagctgcag cagttcctgg accgtttgga
    13861 gcaggaaaga cagttgtaca acaccaagta gctaaatttg ccaatgttga tattgttatt
    13921 tatgtcggtt gtggagaacg tggaaatgaa atgacggatg tactgaatga gtttcctgag
    13981 ttgattgacc ctaataccgg acaatcaatt atgcaacgga cagttctgat tgctaatact
    14041 tcaaatatgc ctgttgctgc tcgtgaggct tcaatttata caggaattac catggctgag
    14101 tattttcgtg atatgggcta ctctgtcgcc attatggctg attcaacttc acgttgggca
    14161 gaagcgctac gtgaaatgtc aggacgtcta gaagaaatgc ctggtgatga gggttatcct
    14221 gcttatctgg gaagtcgtat cgctgaatat tatgaaagag caggacgttc tcaggttcta
    14281 gggcttccag aacgtgaagg aacgattact gctattggag ctgtatcgcc acctggtgga
    14341 gatatttcag aaccagttac tcaaaacact ttacggattg tgaaagtttt ttgggggctt
    14401 gatgctccgt tggcacagcg acgtcatttt cctgcaatta actggcttac atcttattca
    14461 ctatataaag acagtgtggg cacttatata gatggtaaag agaagacaga ttggaatagt
    14521 aaaataactc gtgcgatgaa ctacttacaa cgggaatcta gtttagagga aattgttcgt
    14581 cttgttggaa ttgattctct gtctgataat gaacgactaa cgatggaaat tgctaaacaa
    14641 attcgagaag attatttgca acagaacgct tttgattcgg tagatacatt cacttcgttt
    14701 gcaaaacaag aagcaatgct aagtaatatt ctcacttttg ctgatcaggc aaatcatgct
    14761 ttagagttgg gttcttactt tacagagatt atggaaggta ccgtggcagt tcgagaccgt
    14821 atggcgagaa gtaaatatgt ttcagaagat agattagatg aaatcaaaat tatatcaaat
    14881 gagattacac atcaaattca tttgatatta gaaacaggag gtctataaat gagtgttata
    14941 aaagaataca gaactgctag tgaagttgtt gggcctctta tgattgttga acaagtaaat
    15001 aatgtgtctt acaatgagtt agttgaaatt caacttcata atggagaaat tcgtcgtgga
    15061 caagttttag agatccacga agataaagca atggttcagc tttttgaagg atctagtgga
    15121 ataaatttag aaaagtctaa aattcgtttt gctggtcatg cattagaatt ggctgtatct
    15181 gaggatatgg ttggtcgtat ttttaatggg atgggaaaac caattgatgg tggaccagat
    15241 ttaattccag agaaatattt agatattgat ggtcaagcta ttaatcctgt atctagagat
    15301 tatccagatg aatttattca gacagggatc tcctctattg atcatttgaa tactcttgta
    15361 cgtggtcaaa aattaccagt attttcaggt tcgggcttac ctcataatga attagctgct
    15421 cagatagcaa gacaagcgac tgttttaaat tctgatgaaa attttgcggt tgtatttgca
    15481 gcaatgggta ttacttttga agaagctgag ttttttatgg aagaactcag aaaaacagga
    15541 gcgatcgatc gttcggtttt atttatgaac ttggcaaatg atcctgcaat tgagcgtatt
    15601 gcaactcccc gcattgcttt aactgcggca gagtatctag cttttgaaaa agatatgcac
    15661 gttctagtta tcatgacgga tatgactaac tattgtgaag cgttacgtga agtctcggca
    15721 gctcgccgtg aagttccagg gagacgaggc tatccgggat atttatatac aaatttatca
    15781 actctatacg aaagggctgg tcgcttagtt ggtaaaaaag gttcggtgac acagattcct
    15841 attttaacaa tgccagaaga tgacataaca catccaattc ctgatttaac tggatacatt
    15901 actgaagggc aaattatttt gtcgcatgag ttgtataatc aaggttatcg tccaccaatc
    15961 aatgttttac cttctctctc tcgattaaaa gataagggat ctggagaagg taaaactcgt
    16021 ggagatcatg ctccaactat gaatcaactg tttgcagcct atgcccaagg gaaaaaggtt
    16081 gaagagttag cagtagtatt aggagaatcg gctttatctg atgtagataa attgtatgtg
    16141 aggtttacaa agcgttttga agaagagtac ataaaccaag gattttataa aaatcgaaat
    16201 atagaagata cgttgaatct tgggtgggaa ttactatcaa ttcttcctag aacagagtta
    16261 aaacgtatca aagatgattt gcttgataaa tacttacctt tggtagaagt ttaatccgga
    16321 aatggagtga ttatctatgg tacgtttgaa tgtaaaacca actcgtatgg aattgaataa
    16381 cttaaaggaa cgtttgacaa cagctgaacg tggacataag ttattaaagg ataaaagaga
    16441 tgaattgatg aggcgattta tttctttgat tcgtgagaat aatcaacttc ggaaagaagt
    16501 ggaaagttat ctaattgata atctaaaatc ctttgcagtt gctaaatcat taaagaattc
    16561 tcaaatggtg gaggaattat tttcaattcc atcgaaagaa attgaattat ttgttgagaa
    16621 agaaaatatc atgagtgtaa cagttcctag aatgcatatg aatattactt ctcaaaatga
    16681 gaacagtgaa tacagctatt tatcttctaa tagtgaaatg gatgatgtat ttgctacaat
    16741 gaatagttta atttataaat tactaagact ggcagaagtt gaaaaaacgt gtcagttaat
    16801 ggctgatgaa atagaaaaaa cacgtagacg tgtaaatggt ttagaatact cgattattcc
    16861 aaacttgtcg gaaactattc attatataga attgaaacta gaggaggcag aaagagccaa
    16921 tttagttcgt attatgaaag tgaagtagat cctttattta gattattaat tagatgaaca
    16981 aatatcagct tggataaggc tttaagcctt tctaagcttt ttttattgac agtatcagga
    17041 tatctttttc aaaattttgg tttgttagat aatgaaaatg tttctactaa tctagattta
    17101 ggattagtaa atcgtaaatg taattatata gaaagtaagc gcgtcataac aaggtatcta
    17161 tcattcatgg agctcctcct gtatactatt agtaaagtaa aactattgga ggatatttta
    17221 atgccacaac ctattgttcc tgtagagatt ccacaatctc gtcgttttga ttctaaaaag
    17281 agaaatgata ttctgcttaa aattcgtatt ggcaagcttg aagtaagttt ttttcaatct
    17341 ctcaatctcg aaatggtaga acagcttttg gataaggtgt tgctctatga caattcatct
    17401 atctagccta ggggaggtct atctcgtgtg tgggaaaact gatatgagac aaggaatcga
    17461 ttcactggct tatctggtta aaacccactt tgaattggat cctttctccg gtcaagtctt
    17521 tctcttttgt ggtggacgta aagaccgctt taaagtcctt tactgggatg gtcaaggatt
    17581 ttggctacta tataaacgct ttgagaacgg cagattgatt tggctaagta cagaaaagga
    17641 tgtcaaagct ctcacaccag aacaagtaga ctggcttatg aagggctttt ctatcactcc
    17701 aaaaatatag tagattgaaa ctagaatagt acacctctgc ttctaaaaca ttgttagaaa
    17761 tcgattttac tgtcctgatc gatttgtcct gttcttattt cattttacta taaatccatc
    17821 agaaagtcgt gatttctatt gaaatgagga ctttcttttt atactcatct gctttcaaaa
    17881 agcattctag tccatctccg attaacgatg gactttatca cctccttctc cagtccttgt
    17941 ataacatctt ggagttgatt catgacatct tccaaagttt aaaaggcttt attcttaaat
    18001 ccacgtttac gaatctcttt ccacacttgt tcaatggggt tcatctctgg tgtgtatgga
    18061 ggaataaatg caaagccaat attagtcgga atctttaagg tacttgattt atgccatata
    18121 gcattgtcca taacgagtaa aagataatca tctggataag cttgtgaaat ctcctattcc
    18181 taaagcccct ttagcgcata actttggctc agcttctatt atcgctcaca ccatccatca
    18241 gaagtttaat ctgaaggtac ccaattatcg ccaagaagaa gattgggcta ggatgggttt
    18301 accaatcaca cgtaaggaaa tctctaattg gcatatcaag gcgagtcaat actatttgga
    18361 gcccctttat aacctcttgc gagagagact attgactcag cccttacttc atgcggatga
    18421 aacttcttat agggtgctag agagtgatag tcagctgact tactattgga cttttttgtc
    18481 aggtaaagca gagaaacaag ggattacgct ttaccaccat gatcagtgtc gaagtggttc
    18541 agtagtacaa gaattcctag gagattattc tggctatgtg cattgtgata ttttgcggca
    18601 gtaacttagg actttagtcc tctagttctg cctatgcgat agcagtccaa ggtttaggag
    18661 caaggcgacg ctaagcttgg taaacttcga accgctcgtc tgcttatcgt caactggaag
    18721 aagctgaact tgttggatgt tgggcgcatg tgagaaggaa gttttttgaa gcgccccccc
    18781 aagcaagcgg ataaatcatc cttaggagct aaaggtttag cttattgtga tcagttattt
    18841 tccttggaaa gagactggga ggctttgcca gctgatgaac gactacagaa acgtcaagaa
    18901 catctccagc ccttaatgga agacttcttt gcttagtgcc ggcgtcagtc agttttagca
    18961 ggttcaaaac taggaagggc aattgaatac agcctcaagt atgaagaaac ctttaagacc
    19021 attttgaaag acggacatct ggtcctttcc aataatctag ctgaacgcgc cattaaatca
    19081 ttggttatgg gacggagtaa aagagtccag tggactcttt tagcctaagc tcagtttaaa
    19141 aaagcgaggg tggttatttt ctcaaagttt tgaaggagct aaagcaagag ctattattat
    19201 gagtttgttg gaaacagcta aacgtcatca attaaatagc gagaaatatc tatcctatct
    19261 tctagaatgt cttccaaacg aggaaactct cgtaaacaaa gaggttttag aggcttattt
    19321 accatggact aaagttgtac aagaaaagtg caaataagaa atctccagat taggaactat
    19381 ccgtgagttc tccagtctgg agatttttca atagacttcc tgcgaaacaa aatatggtat
    19441 agtagttcta tgaatgatga agcaagtaaa caactaaccg atgcacgatt taagcgtctt
    19501 gttggtgttc aacgcacgac ttttgaagag atgttagctg tattaaaaac agcttatcaa
    19561 cttaaacacg caaaaggtgg acgaaaacct aaattaagtc tagaagacct tcttatggcc
    19621 actcttcaat atgtgcgaga atatcgaact tatgaacaaa ttgcggctgt ttttggtatt
    19681 cacgaaagca acttaatccg tcggagccaa tgggttgaag taactcttgt tcaaagtggt
    19741 g
//
LOCUS       DBEJJV010000037        18995 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.037, whole genome shotgun sequence.
ACCESSION   DBEJJV010000037 DBEJJV010000000
VERSION     DBEJJV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18995
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.037"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(126..452)
                     /locus_tag="ACL3GT_001595"
     CDS             complement(126..452)
                     /locus_tag="ACL3GT_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517240.1"
                     /translation="MILWGFDFANDHAHAFFMDNVEWSHADSYFLSFVSDDVEERYTE
                     NVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSVGTSPEQYPDYDG
                     FDYEEW"
     gene            complement(866..2746)
                     /locus_tag="ACL3GT_001596"
     CDS             complement(866..2746)
                     /locus_tag="ACL3GT_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HGR0517241.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVMGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2740..3609)
                     /locus_tag="ACL3GT_001597"
     CDS             complement(2740..3609)
                     /locus_tag="ACL3GT_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HGR0517242.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLYRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3693..6338)
                     /locus_tag="ACL3GT_001598"
     CDS             complement(3693..6338)
                     /locus_tag="ACL3GT_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HGR0517243.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEVTIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGEQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6429..7709)
                     /locus_tag="ACL3GT_001599"
     CDS             complement(6429..7709)
                     /locus_tag="ACL3GT_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HGR0517244.1"
                     /translation="MIYPKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7880..9964
                     /locus_tag="ACL3GT_001600"
     CDS             7880..9964
                     /locus_tag="ACL3GT_001600"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HGR0517245.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLVSSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKILVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(10004..11683)
                     /locus_tag="ACL3GT_001601"
     CDS             complement(10004..11683)
                     /locus_tag="ACL3GT_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004560 - alpha-L-fucosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HGR0517246.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYNQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQQVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLYFYLNLTVDGQLVDQLQVQVS"
     gene            12439..13668
                     /gene="arcA"
                     /locus_tag="ACL3GT_001602"
     CDS             12439..13668
                     /gene="arcA"
                     /locus_tag="ACL3GT_001602"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HGR0517247.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13726..14742
                     /gene="argF"
                     /locus_tag="ACL3GT_001603"
     CDS             13726..14742
                     /gene="argF"
                     /locus_tag="ACL3GT_001603"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HGR0517248.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14907..15854
                     /gene="arcC"
                     /locus_tag="ACL3GT_001604"
     CDS             14907..15854
                     /gene="arcC"
                     /locus_tag="ACL3GT_001604"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HGR0517249.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            16065..17576
                     /locus_tag="ACL3GT_001605"
     CDS             16065..17576
                     /locus_tag="ACL3GT_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HGR0517250.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17598..18929
                     /locus_tag="ACL3GT_001606"
     CDS             17598..18929
                     /locus_tag="ACL3GT_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HGR0517251.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         5321 a         4306 c         3910 g         5458 t
ORIGIN      
        1 tcggattacg aatgaatttg agtgctggta ttatcaatca tgaattagga ttctagtttt
       61 gcaggaagtc tattgaaata ctaagcctac acagactgat tccaattgtt ttttagattt
      121 caattttacc attcttcata gtcaaaacca tcataatctg gatattgttc tggcgacgtt
      181 ccaaccgaac gtacgagata agcttcttcg tcctctgtct cgatttctct cagtacttgg
      241 cattcaaaac gccattcatc accgaagtcg aaaataaact taaatttttg tttgacactt
      301 aggctatcca gatagacatt ttctgtgtaa cgttcttcaa catcgtcact aacaaagcta
      361 agaaagtaag aatctgcatg actccactca acattatcca tgaaaaatgc gtgagcatga
      421 tcatttgcaa aatcaaaacc ccataaaatc acatctgcta gttccgctaa cgtttttgtt
      481 tttggaatct atatatgtcg gtagcaacct tttttaaatt tgacggaaat gatccaagct
      541 tctacagatg ctggcttttc agcttctatt tcttgtttta ctaattttaa gtgtagcata
      601 atacctccaa ttgctcatcg atagaattgc tcttaggaaa cattcacttt ctgctatttt
      661 atcataagtt tgtctaactg tagcatttga aaccagataa ttcttctgtt tcacgcgaaa
      721 caccctgcgc caagcaaggt gttcttgttt ttatactcaa tgaaaatcaa agagcaaact
      781 aggaagctag ctgcaggctg ctcaaaacac tgttttgagg ttgtagatgg aagctgacgt
      841 ggtttgaaga gattttcgaa gagtattaag tcgtataaat cgtcgaagct gtcgcaatgg
      901 tatgccactg gttagctgta gttgctgcga aatccttgtc tgcgtagaag tcagtaaatg
      961 gtaggatttc aacttccagc tcgtcgatgc ggtcaagctg gccagccaga taaacctcga
     1021 tacggctttc tgctcgtttg atgcgttgca agagtccgcc catacggatg tcaactgtat
     1081 ccaaaccaaa gaccttgttt tctttcaacc attggtgact aaagagggca tggaagtctt
     1141 caatttggct tctaagttct ggtaattctt gtctggcgat ttgttgtaaa ctttctttat
     1201 catccgcttg gtaggcctga cgaatgcgtc gtcccacatc tactttgcta cttaaaatag
     1261 cattcaactg ggcctgagtt tcaaagagat aagcatagtt tccagctttt tctttaatgt
     1321 cagcaatagt tcccgccgcc tgagcgaagt gtggcttgtc ctgttcaggt gtcatgtgtc
     1381 ggtcaagtat cggacagaga acatcctgat aaaagacata gcggttggga ttgatgccac
     1441 tgagattacc tggtaggtct ggtaagaggt tggcaaggtc aatctgcata aaatcctcaa
     1501 ccgttagacc agtattggtc ttgaaatgcg cagacaaact atctaggtca ttgcgatagc
     1561 tgagttctgc ccagatttgc aagcttggta ggatagagaa ctgggcagtt tcaccaccat
     1621 tgtctcccca acccattacg atgacttctt taatctgatt ggcacggcag gctttattag
     1681 cctcgatagc cactagacgg ctaaaatggt tgtgaggtgt aaagccaatc cacttccaag
     1741 ctccccctgc aaatgcaagg tcatggctaa tcttgtgatg attgcggaaa ttacggttgt
     1801 atttttcctc gctatcctga taataatccc agtaaaccag agtcacacgg tctttgagac
     1861 ggtctaggta gacacgagtt tcctctggaa tttccacatc acgatcgtac tggccatccg
     1921 ctgacatgag tttgaagaac atatcactcc acatctggca gtggaaacca tatttgtcag
     1981 caatatccag cacgcgctcc aagtgttggc acatgaggag actacgatcc acaacaccgt
     2041 tcaaaatcag gtagcgtccc aaaccaacca agtgggcttc gtccatcccg atattgacct
     2101 tgcgagtctt cagtttagac aacgtggcaa acatgccatc aatcaggtca taaacctttt
     2161 cttcgccaat gagaagaatg tcctctacat cacggagctc ctgcacttcc ttgacacccc
     2221 atttgacaaa ggccgacaag tgggccaagg tctggatgca tggtacaaag gtcatgtcaa
     2281 actgttgagc ataggcttcg atttcctgca actcctctgc tgaataagct ccacggaaat
     2341 agccaaagta aggctgtcct tcaatctggt aagtgtcttc catgtaaagc tcaaaggttg
     2401 agtagcccat gagagccaag acctcaatca tctgcttggc agaagccaca ttcagcaccg
     2461 catttcgaga acagtcaacc atgtaagcca aatcttcgta agctgcttgt tcctcaatct
     2521 ctactttatc agcttctgct agaactgtta ccaacaagga taaggcacga taaagttggt
     2581 gaggtttgcg gtaggtcaat tgatagtgac cttcctcacc ctcgatagag atagaggctt
     2641 ggtcagactg agtgacagcc acttccacat ctggtagaga aatgtgacct tttaaaacct
     2701 caatagcttg cgtttgtttg ggactaagtc ctgtaaatct taccattgct tttcctcctg
     2761 tagccagttg acaagggcac cgtagagatt ggcatctgcg tgataggtgc aggcctggat
     2821 aactggtgcg accgtgtatt cttcgtaggc atcgacaaag tcttcaacag ccttcttaac
     2881 accttggata aaatctggat tttgactgat agagccaccc agactgatga catctggatc
     2941 gatcagatac tggatattga gcaagccttg cgtcagattg cggttcatgc gctcaatggc
     3001 ttcttgacaa agagcattac cagctgcggc ctcttggtaa atcttgcgac cgtcccaatc
     3061 agtatgacca gatttttcaa tcacgtatcg taccatattc ccagttgatg ctagttgcga
     3121 ccagttatta agtttttcag caggggcaag ggttgtcatg tagccaaatt ctccacccag
     3181 accgtggcga cctcgataaa gtctaccatt gataatcatg gctccgccaa tccctgtccc
     3241 aatcacgaca caggctgcat tttcaagctc tggatgagct agtagttcac tgagtccaac
     3301 gcagttggca tcattttcta aatggacagg tagctgataa gagctaagcg cctcatacca
     3361 agaaaagcca tggatgtagg gcaccgcact gaagccatca atcacacctg tctcttgatt
     3421 gaccgcacct ggaacgctca tagcaatccc actgtaatcc tgttctgaca agcgttgatc
     3481 tagccacgct agtaaatcct ccaagttttc aggcgttgaa atacttgtct tatccagtat
     3541 tttcccatca ggagtcagac tggcaaactt aatcccagtc cctccgatat caatcgttgc
     3601 aatggtcatt gtttttacca taaaaagggg cgaatcagca gttagttctt actttttcgc
     3661 ccctcctttc ttttgatgtt tactttttga aattaaattt cttctttttt gatgaattct
     3721 gtacgaatct cttgtggagc caatagtcct gaatgaactg gatatggtcg ctcaagtaag
     3781 tcaagaatgg tttgttgatg ttctgatatg cgcacatttt cttgactcat attatagtaa
     3841 cggaggacat agccttcttc attttccgcc actttaaagg ctgttggaca aacttgcggt
     3901 atgctgagaa cagaatggct caagaggcta ccagtcgcaa ccacgcttcc ttcctgtcta
     3961 gcaagctgaa ggctggtaaa cggtgtctgc aaggctttgg cacgacgata ggctgagaag
     4021 cgttcttggg cttggtggca ttcaatcgca aattcgactt caaactcacg caagcattgt
     4081 gcttctggcg ttgggaagta gccccagtca cctagctcac ctgatgcacg caaaatggtc
     4141 acggcaatgg tgttatcccc aaggatttcg tattcattca atcccttgtt ggatacagtc
     4201 accccttttt catcgtcata cagactgaca aaagcttgtt ggtgttgagg attttcagga
     4261 ttttcccatg aagcagctgg tttgtttggt cgtgtcacca cctcatagat actttcagaa
     4321 tcattgcttg gacgcgtgtt atgagtcttg accaagagac ggatacggtg atccttggca
     4381 gtgttagtaa agcgagtctt gaagcggatt tgtggattgt caacaaagac aatcaactca
     4441 gtttccagag gaatgtttgt caattcttct gaccgtccag cctcacgctt cataaactcg
     4501 atgatacctt gttgctcttc ttctagcttt tcatccgcac tgacaggcac ggtcaattca
     4561 tgtttgagca agattttagc atagcgatct gtgttttcca agacctcgtg gcccttaagc
     4621 tctgcaaaga ttggctctgt tccttttggt tggaaataga tatactcgtt tccgatgtca
     4681 ccccggtctt cgaagcggat aaaatcttca taggcttcgt gagttgtctt atcatagact
     4741 gtgatgttgt catccacact caccgttacg aatggtgtat caatcactcc gttttggtaa
     4801 ataccctcac ggtgttcttg ttctccttcc agcaattgga aggttgtcca agaaagcggt
     4861 gctaggtgaa ctggaatggt cacgcgcact tgtcgagcaa tacgagcttg gcggaactta
     4921 tcttttggta aatcgtattc aaaattagct ccgaggtctt cgattgtaac ctctacagga
     4981 cgaccatcca agtcctccac acggtaactt ggcaagataa gagcagccat ctttttgtag
     5041 ccttctgttg ggtgcaattc cttgaaatca caagtcgcca catcaatcac tgtgctgaca
     5101 gtatcgacct tatcatgcaa gcctgtgtta atgacagtaa agagatagtc actttgagcc
     5161 ttatccgtag caattttacc cttccactcg ttgagcaaat tacttttaac aaagtttcct
     5221 acttggttga ccttggcaaa acgcgtttcc atctcgcggt gaacttcgtc cacgctacag
     5281 ccacagatac tatcatgtgg cgcattctgc aaaagtgttt tccaagcata ggtcaactgg
     5341 tccttgtggt tgtgtccacc agtgataata gtcaagggtt ctaccacttg ctctaggagg
     5401 ttgctatttt cttggaaggc ttgttttagg taaatgcggg atgaagaagt gttggcaagt
     5461 gtgtaccagc catctgtttc ctgactggtc aactcgcctg taacagttga taagtgttca
     5521 ggaagcgcac cttctacagc ttgaacatat tcatcaaaag aactatgaac aaagattaca
     5581 tccgggaaga gttcatttgc cacacgaatg gcttcgctca gatttttctg tacaggctgg
     5641 tggtcacagc cgttcatcat caaccattgg ttggtcgaag cgtaggcacg cacatctgac
     5701 aatttttgtt tccagaaggt caaggcctca tctttgtcaa ctgggatttc attcccatta
     5761 ctgtaccagt tggcaaagag aatacctaaa acacgactac catccacacc ctgccagtac
     5821 atttctgaaa actgggatgt aaactgctca tcttcaagga cttggttgtc aaatccaatc
     5881 ggcttcacac cacgaccaaa ggccgccacg tgaatgcctg atttttgaag aatttgaggc
     5941 gcttgtccca tatttccaaa ggtatctgga aagtagccaa tctgggttga tttaccccat
     6001 ttggcagctt cttgttgacc aatcaaggta ttgcggacat tggcttcact ggagatcaag
     6061 tagtcatcct gcaagatgta aaagggacca attttaagtt tgccctcgtc aatgtagcgt
     6121 tggaccttgt cgcgattttc agggcgaatt tgtaagtagt catcaaggac aatagtttgt
     6181 ccatccaagt ggaaactctt gaactcaggg tcattttcaa agagatcaaa gagattgtca
     6241 aacaattcca ccaactgcat acgatggctt tcaaaaggca agtaccactc acggtcccag
     6301 tgactatgtg agataatatg tacaacaaca ttttccatga agtaaaacct cattctaaat
     6361 ttaaatttta acgttttaaa tgtaaacttg tgattctgat aagaatcggt tgagctaaag
     6421 cgagcccctt agcgaatatc caagtaatcc aagaccaact cacagaacat catgttagcc
     6481 caggagaacc attcacgaga gtagagggtc ggatcatcta cgtggaagct ttcgtgcatg
     6541 acacctgtac caccatcgca ggcaaccagc tgatccagca agaatttttt ctctgcctta
     6601 tctcttgttg tcaatccttg gatagaaagg gcgattggcc agatatagcg atagaaggta
     6661 tgagaacttc cgagaccgct agcgtattct ccttggtaga agtatggatt ttcagagctc
     6721 agaatggtac ggcgagtggc ttgatacact tcatcatcga tcgaacagta gcccagatag
     6781 ggcgcagcta gtagacttgg tacatttgga tcatccatga tgctggcatt tcctaggcca
     6841 tctacttcaa aagcgtaaat cttttcgccc ttgctgttgg tggtgtaagc gtagttttcg
     6901 attccttctt ggatttcatc ctgaagacgc ttggcatcag caataacact ctggctatca
     6961 gctaggttta atgctgcgaa gatttcttgc acataaccca agactactac agcaaacata
     7021 tttgacggaa tcaagtaact atactggcaa cagtcatcac tcggacgaaa ggctgaccaa
     7081 gtcatacctg tcactgcaaa gtcaggtcca aagccatcat ttaccaaggt gtcttcctta
     7141 cggtccgtat ctcggacaaa acgataagga gagttcttgt ggtcttgttc aactgtccat
     7201 agatggagaa tttccttagt cgctgcgaca aaagtctcat caaactgact agtctcgcca
     7261 gtttctttcc agaggagata agccaactgc aaaggatagc aaagcgagtc cacctcatac
     7321 ttgcgttccc aaatccagcc attaaggtcg gtgtggtcgg tctcgtggtg ccccttccag
     7381 ttttcctcta tgttgaagga attggcataa ggatccttga gtaccaaggt catctgacgt
     7441 ttgaccaaac ctgcaatggt ctgacgcagg agggcatctc ttttagctac atgcaggtag
     7501 ggtctgagtt gggctgtcga atcccgaagc cacatagcag gaatatcccc agtcaagaca
     7561 aaagttgaac catcttctaa gatttcaacc gtattgtcca aggtatcggt gtagcaacgc
     7621 tcgaaaacat ccacccactc tggatggtcc ttagcccgct ctgctacttc atctagccat
     7681 tctctaacaa tttctttcgg ataaatcatc gtgcaattcc ctctttcaaa caagtttcat
     7741 gttcagtata tagcttttga gacagaaaat acatacacaa atgatagtca tttttctaca
     7801 aaatagttat ttttgaaact ccttttctaa aggccctctt tttctgatat aatgtagaaa
     7861 aacagctaaa ggaaagacta tgaaaccact acttgaaacc atcgataccc gctttggtac
     7921 tgctagcaag catgccttct cttggggaaa taccctgcca tacacaggcg tgccttttgg
     7981 gatgaattac tttgtgcccc agaccagtga ccaggatgga tcttggtttt ttgatccgca
     8041 tctgcctatc tttcagggga ttcgattaac tcaccagccc agtccttgga ttggggacta
     8101 ctcttggctc cttctgacac ctgtcaccag tcaactgggg ggagacagcc tctttcaccg
     8161 ccagtcttct tatgatatag ataaagcttg cttccagcct cactatttga agctcttttc
     8221 tctgcgttat cagattgaaa cccagctcac accaacttgc tatggtgctt ctattcgttt
     8281 gaatcaaaag caaggcaaag ccctctccct ctatcttcac gcagcagatg aactgacagt
     8341 agagcaagta gataagcgga ctcttgccct gcgacaagaa ggtaaaactg aaactaacaa
     8401 aaattcgcta acgatgttca ctgccctgca aatgaacacg gatattcttg ctatcagcca
     8461 agaagctgga gactggcgaa ttgacttagt aagtagtcaa accgagatgc aactagccac
     8521 ttctttcatc tctccttctc aagctctaat caatctacct caagaagatt ttgatagctg
     8581 taaatcaagt gcccaagcgg attgggaaaa tctcctccat cgttttgaca ttatagagac
     8641 aggagaggct gaccgaacct tctttgacca ctgcctctac agactcttcc tcttcccaca
     8701 gactttttat gaggttgatg agtcagggca agccatccac atggatctgg ctactggtac
     8761 tgtcaagcct ggtgtcctct ttagcaacaa tggtttctgg gataccttcc gcaccacctt
     8821 ccccctcttt gcccttatca taccggagca ctatcaacgc tttttagaag gtttcctcaa
     8881 tagctaccgc gatactggtt tccttccaaa atggctggct ccagatgaac ggggtatgat
     8941 gccaggtaca cttttagacg gtattatcgc agatagcgcc tgcaaggaca tggcccctga
     9001 cctagaagga gaactcttcc aagccatgct cgaaacagcc agcaaagccg accctctcgg
     9061 catcaatggc cgccacggac tagcccaata ccaagaacta ggttacctct ctaccgacca
     9121 ccatgaaagt gttagccata ctctagacta tgcctatagt gacttttgta tcgccagctg
     9181 tgccaaaaaa ctagagaaca tagaaatcgc tgaaacctac aaggctgctt cacaaaatta
     9241 ccgccagcta tttgacgctg agacaggtta catgcgagca cgagacaatc aaggaaactt
     9301 tcaccctgac ttctctcctt atagttgggg gcgagactac gctgaatgct ctgccattca
     9361 agctacttta ggcgttctcc acgacatccc tggcttaatc caactgatgg gtggaaaaga
     9421 aacctttagc aactatcttt tgaaagcctg tcaagatgct cccctctttg aaacaacagg
     9481 ctatggttac gaaattcacg aaatgagcga gatggctact gctccttttg gacaaatagc
     9541 catttccaac cagcctagtt tccacattcc ttatctcttc cgctacagcg attaccctga
     9601 ctacactgcc cttcttatca agacgctccg tcagaaagct tttcacccaa gttgggaagc
     9661 ctatcctgga gatgaagaca atggtagtct ctctgcttgg tacatctggt cagctctcgg
     9721 attttatcca acctgtccag gaaaaccaag ctatgacctc ggaatccctc tctttgacca
     9781 tctacgagtc tacctagcta aagaagataa atggctggat atccatacta aacaaaacca
     9841 caaccatttt aactttgtca aagaatgccg actggacaaa atactcgtat caactattca
     9901 acaccaagac ctcttaaaag ctgaacaact aactttcacc ctcagctggt taccaagtca
     9961 ctaataacca aaagaacctt tgcatcgcgc aaaggttctt cttttatgaa acttggactt
    10021 gaagttgatc cacaagctga ccatccaccg ttaggttcag atagaaatac aaggttttat
    10081 ctcctgcgaa atacaaggtt ggtagcgtca gacttttttc agtctcacca gcttgaaacg
    10141 caaggacttg aatctcatcc tgataggcga caccatggac acctgtcccc ggttgaatcg
    10201 aaatcttagc ttctaaagga ccactacatt ctctgcgctt aactgtaaaa taggcatttt
    10261 ctccctttgc cacagctagg cttttttctg caaatgctag ttcctgaaca acttcttttt
    10321 ttgataatcc aggagtttta taaagggaaa tcttggtcaa tacaggaata gattgtgcct
    10381 cggtaatcat cacgcgcacc ttctgtgcct ctactagcgg acctcgcaag aggcgcttat
    10441 gaccaactgt gaagcccctg ccaaattcct gccagacacc atccacctct acttgcacat
    10501 gaaaagcagc gattcgttgc cctagcttca aatcttctct taactcaatt acatcaaaag
    10561 ttttaggaga acctaagtcg agttctaact ggatgggcaa gtctgcatcg tttgcccaag
    10621 agctggtctc aaggccgtct gtcaaatggc gacaagcaaa gtctgcggaa agagctggac
    10681 cagatacctc agctcccaga gccaaatctt ctttatagag ctcattgcga taggtcgcaa
    10741 attcataaag tcgttcaata tcctttgcat caaagagccc agcttgattc ggcggaatat
    10801 taagcaagag tggagttcct cgccctactg agtgaaagta gatttcgacc aactcctcga
    10861 gagacttagg atcctgatcc tcatggtaga accagcctgg acggatggaa acatctgcct
    10921 ctccgattga aaaaatcgtg cccgagggat ccccgtgctg aagatagtcc agctctgctt
    10981 ctgttcctag tttatcagga ttcacctttt gccacagtgg atcacctgca taccctcgtt
    11041 cattgccaat ccagcggata ctggtgcctt ctgttgaaaa aatcaaacaa tcgccctgca
    11101 agtcacgaat ggtttcaaac catttttcaa attcataatt gacctgctgg gccccttccc
    11161 ctctagcacc atccatccaa acctcagcga acttaccagc attcccatag ttaggatttg
    11221 ataagatttc cttcaactga gccagataat aggcattgta gtccgcttct cggtccacat
    11281 gatagagggg actatgggca tcccacggtg acaggtagac ccccatatcc atatcaaact
    11341 ctgtggcagc ttgggatact tcaaggagca agtcgccctt tcctctcctc caaggactga
    11401 ccttaaccga ataatctgtg tgagctgtcg gataaaggac aaagccatcg tggtgcttga
    11461 ccaccaaaat caactttttg aagcccgttt ccttgagcac acgaacccac tcacgcgcat
    11521 ccaactgact cgggttaaag cgctcaggat cctcctgacc tgttccccat tcctgattat
    11581 aaaaagtatt aggtccaaaa tggataaagg ctgctagttc atctcccaga taagctagct
    11641 gagtctgact tggtaacggt ccatgcggtt tgattttctt catcgttata tatctccttc
    11701 ttttgcaact tctcttgttc acaaggttat ccacaggttg tggataataa accatgatct
    11761 aacagccagc tctttccaac tccaactggt aggctcagga tttttctcct caatattccc
    11821 tcttcaaaca gctctgtcat atggttctgc taacacctct cagaatgcta ctctccataa
    11881 ttattctcag gcttctttca ggtcattgtg tgaagaccat tcactctcca gacttttcca
    11941 cagattgtga ataagtgatt attctaaact atcacctcgt cgactataac aaaaaataaa
    12001 aagagggtca ataagataat tatctcttcc taaatactca gaaaagattc tataatttgt
    12061 acaattgaac aagaaatgct tctccaaaat ctatcttcaa aagaatgttg catcttttta
    12121 tcctttcaca caaacatttc tctttataca gatccaagtg ataaccagat gataattgga
    12181 cactttttgg ttatttgtgt attttttgaa aaatttttta aaaaaatttt atatcctctt
    12241 taatagaagt ttatgcattt gtatatatgt attccatcct atgttgtgta taataacata
    12301 aaattgtgct aaatatcata atttatatta ttttccgaga aattatagcc attgacatta
    12361 cctaggaatt gcgttataac atacatgtaa gcggtaccca aaatggtgcc aagtcaaaat
    12421 ttttaaggag gaaaatacat gtcttcacat ccaattcagg tcttctcaga aattgggaaa
    12481 ctgaaaaaag ttatgttgca ccgtccaggc aaggagttag aaaacttgtt gccggactat
    12541 cttgaaaggc ttctttttga tgatattcct ttcttggaag atgctcaaaa agaacatgat
    12601 gcatttgccc aagctcttcg cgatgaagga attgaggttc tctacctaga acaactcgct
    12661 gctgaatcat tgacctctcc agaaatccgc gatcaattta tcgaggaata cttagacgaa
    12721 gccaacatcc gtgatcgtca aactaaggtt gctattcgtg aattgcttca cggcatcaag
    12781 gacaaccaag aattggttga aaaaacaatg gctgggattc aaaaagttga attgccagaa
    12841 attcctgacg aagctaaaga tctaactgac ttagttgaat cagattatcc atttgcaatt
    12901 gacccgatgc caaacctcta tttcactcgc gacccatttg caacaattgg aaacgccgta
    12961 tcgcttaacc acatgtttgc agacactcgt aaccgtgaaa cactctacgg taagtatatc
    13021 ttcaaatacc acccaatcta tggcggaaaa gtggatttgg tctacaaccg tgaagaagat
    13081 acgcgtatcg aaggtggaga cgagctagtt ctttctaaag acgtccttgc agtaggtatc
    13141 tctcaacgta cagacgcagc ttctatcgaa aaacttttgg tcaacatctt caagaaaaat
    13201 gttggcttca agaaagtttt ggcctttgaa tttgctaaca accgtaaatt catgcacttg
    13261 gatactgtct tcactatggt agactatgac aagttcacta ttcacccaga aatcgaaggc
    13321 gaccttcacg tttactcagt tacttacgaa aacgaaaaac ttaaaattgt tgaagagaaa
    13381 ggtgacttag ctgaacttct tgctcaaaac cttggtgtag aaaaagttca tttgattcgt
    13441 tgcggtggtg gcaatatcgt agcagctgcg cgtgaacaat ggaacgacgg ttctaacact
    13501 ttgaccatcg cacctggtgt ggtagttgtt tatgaccgca ataccgtgac caataagatt
    13561 ttggaagaat acgggcttcg cttgattaag attcgcggaa gtgaattggt tcggggccgt
    13621 ggtggacctc gttgtatgtc tatgccattt gaacgtgaag aagtgtaatc gctgttcggt
    13681 attcgtcaat agaaaatgta aaaaatagaa agaggaaata ataaaatgac aaattcagta
    13741 ttccaaggac gcagcttctt agcagaaaaa gactttaccc gtgcagagtt agaatacctt
    13801 attggtcttt cagctcactt gaaagatttg aaaaaacgca atattcaaca ccactacctt
    13861 gctggcaaga atatcgctct cctatttgaa aaaacatcta ctcgtactcg tgcagccttt
    13921 acaactgcgg ctatcgacct tggtgctcac ccagaatacc tcggagcaaa tgatattcag
    13981 ttgggtaaaa aagaatctac tgaagatact gctaaagtat tgggacgtat gtttgacggg
    14041 attgaattcc gcggattcag ccaacgtatg gttgaagaat tggcagaatt ctcaggcgtt
    14101 ccagtatgga acggtctaac tgacgaatgg cacccaactc aaatgctcgc tgactacttg
    14161 actgttcaag aaaacttcgg tcgcttggaa ggcttgacat tggtatactg tggtgatgga
    14221 cgtaacaatg ttgccaacag cttgctcgta acaggtgcta tccttggtgt caatgttcac
    14281 atcttctcac caaaagaact cttcccagaa aaagaaatcg ttgaattggc agaaggattt
    14341 gctaaagaaa gtggcgcaca tgttctcatc actgaagatg ctgatgaagc agttaaagat
    14401 gcagacgttc tttacacaga cgtttgggta tcaatgggtg aagaagacaa attcgcagaa
    14461 cgtgtagctc ttcttaaacc ttaccaagtc aatatggact tagttaaaaa agcaggcaat
    14521 gaaaacttga tcttcctaca ctgcttgcca gcattccacg atactcacac tgtttatggt
    14581 aaagacgttg ctgaaaaatt tggtgtagaa gaaatggaag taacagacga agtcttccgc
    14641 agcaagtacg ctcgccactt cgatcaagca gaaaaccgta tgcacactat caaagctgtt
    14701 atggctgcta cacttggtaa cctttatatt cctaaagtat aattttagat aataaaccgt
    14761 ctaccaacag ctatgagggc tgcgactaat agctttagtc cggtcctctt ttatataatg
    14821 gtaatctatt atttcttata aaatatgtga aaaatcatta aattgaaatc taaacgcatt
    14881 ctattgagtg tgataaagga gaatttatgg caaatcgtaa aattgtagta gctttgggag
    14941 gaaatgcgat tctttcttct gacccatcag caaaggctca acaagaagct ttagttgaaa
    15001 cagctaagca tcttgtaaaa ttgattaaaa atggagatga tctgattatc actcacggta
    15061 atggacctca agttgggaat ctcttgctcc aacatttggc atcagactct gaaaagaacc
    15121 ctgccttccc actcgactca cttgtcgcta tgacagaagg tagcatcggt ttctggttga
    15181 aaaatgcttt gcaaaatgct ctcttggatg aaggcatcga aaaaaatgtt gcctctgttg
    15241 taacgcaagt tgtcgtagat aaaaatgatc cagcttttgt taacttgagt aaaccaatcg
    15301 gtcctttcta ttcagaagaa gaagcaaaag cagaagccga aaagagcgga gcgactttca
    15361 aggaagatgc tggccgtggc tggcgtaagg tcgttgcctc accaaaacct gttgacatca
    15421 aagaaattga aaccatccgt actcttttaa ataatggtca agtcgtcgta gctgcaggtg
    15481 gtggcggtat tcccgtcgtc aaagaaaaca atggacattt gactggtgtc gaagcggtta
    15541 ttgataaaga cttcgcttcc caacgtttgg cagaattggt tgatgcagac ctcttcatcg
    15601 ttttgacagg tgtagattat gtatttgtta actacaacaa gccaaaccag gaaaaattgg
    15661 aacatgtgaa tgttgcccag ctggaagaat atatcaaaca agatcagttt gcaccaggta
    15721 gcatgcttcc aaaagtagaa gcagctatcg cttttgtcaa tggtcgtcca gaaggaaaag
    15781 cagttattac ttcccttgaa aatctaggcg ccttgattga atctgaaagc ggaacaatta
    15841 ttgaaaaagg ataagttgtt ttactaataa gatgtattct atttctagta tctttatatc
    15901 aaattagaaa ttattcttga aaacatgtac aatatttcaa aagatattag ttttttagac
    15961 tttaatatgg taaaacaaat ataaatagaa agcgttttct taaatgttta tttaagaaag
    16021 tagttggttt tttacacttt gttagacatc aggaggaaaa acaaatgagt gaaaaagcta
    16081 aaaaagggtt taagatgcct tcatcttaca ccgtattatt gataatcatt gctattatgg
    16141 cagtgctaac ttggtttatc cctgcggggg cctttataga aggtatttac gaggctcagc
    16201 ctcaaaatcc acaagggatt tgggatgtcc tcatggcacc gattcgggct atgctaggta
    16261 ctcatccaga ggaaggttcg ctcattaaag aaacgagcgc agcgattgat gtagccttct
    16321 tcatccttat ggttggtggt ttccttggca ttgtcaacaa aactggtgct cttgacgtag
    16381 ggattgcctc tatcgtgaag aagtataagg gccgcgaaaa aatgttaatt ttggtactga
    16441 tgcctttgtt tgccctcggt ggtacaactt atggtatggg ggaagaaaca atggccttct
    16501 atccactcct tgtgccagtt atgatggccg ttggttttga tagcctgact ggtgttgcaa
    16561 ttattttgct cggttctcaa atcggctgtt tggcatctac tctgaatcca tttgcgacag
    16621 gtattgcttc agcgactgcg ggagttggta caggggacgg tatcgtactt cgtctgattt
    16681 tctgggttac cttgactgct cttagtactt ggtttgttta ccgttatgcg gataagattc
    16741 aaaaagatcc gactaagtca ctggtttata gtactcgcaa agaagatttg aaacacttta
    16801 acgtagaaga atcttcatct gtagaatcta cacttagcag caaacaaaaa tcagttctct
    16861 tcttatttgt gttgacattc atcttgatgg tattgagctt cattccatgg acagaccttg
    16921 gcgttaccat ttttgatgac tttaatgctt ggttgactgg tcttccagtt attggtaata
    16981 ttgtcggttc atctacttct gcactaggta cttggtactt cccagaaggc gccatgctct
    17041 ttgcctttat gggtatcctg attggtgtta tttatggtct taaagaagat aagattatct
    17101 cttccttcat gaatggtgct gctgacttgc tcagtgttgc cttgatcgta gcgattgctc
    17161 gtggtattca agttatcatg aacgacggta tgattaccga tacaatcctc aactggggta
    17221 aagaaggctt gagcggtcta tcttcacaag tctttatcgt tgtaacttat atcttctatc
    17281 tacctatgtc attcttgatc ccatcttcat ctggtcttgc cagcgcaact atgggtatca
    17341 tggctccact tggagaattt gtaaatgtcc gtcctagctt gattatcact gcttaccaat
    17401 ctgcttcagg tgtcttgaac ttgattgcac caacatctgg tattgtgatg ggagctcttg
    17461 cacttggacg tatcaacatt ggtacttggt ggaaattcat gggcaaactc gtagtcgcta
    17521 ttattgtagt gaccatcgcc cttcttctcc ttggaacctt ccttccattc ctataaaata
    17581 gtgagtgagg tgattccatg aaaatagata taacaaatca agttaaagat gaatttctta
    17641 tatcattaaa aaccttgatt tcctatcctt cagtactcaa tgaaggagaa aatggaacac
    17701 cttttggaca agcaatccaa gatgtcctag aaaaaacttt agagatttgt cgagacatag
    17761 gtttcactac ctatcttgac cctaaaggtt attacggata tgcagaaatc ggtcagggag
    17821 cagagcttct ggccattctc tgtcatttgg atgttgttcc atcaggtgat gaagcagatt
    17881 ggcagacacc gccatttgaa gcaactatca aagacggctg ggtattcgga cgtggtgtcc
    17941 aagatgataa aggcccttcg ctcgcagctc tctatgcagt aaaaagcttg ctggaccaag
    18001 gtattcagtt caaaaagcgc gtacgcttta tctttggtac cgatgaggaa accctctggc
    18061 gctgcatggc acgctacaat accatcgaag aacaggccag tatgggcttt gcacctgact
    18121 catcttttcc tctgacctat gctgaaaaag ggcttctaca ggtcaaactt catggcccgg
    18181 gatcggatca actagagctt gaagtaggag gcgcctttaa cgttgtacca gacaaggcca
    18241 actaccaagg tctcctctat gaacaggttt gtaacggtct caaagaagct ggttatgatt
    18301 accaaaccac tgaacaaacc gtaacggttc tcggagtgcc aaagcatgct aaggatgcta
    18361 gtcaaggtat caatgctgtc atccgactag ctaccattct tgctcctctc caagaacacc
    18421 ctgctctcag ttttcttgca acacaagcag gtcaagacgg cacaggaaga caaatctttg
    18481 gtgatatagc agatgaacct tctggtcacc tatcctttaa tgtcgcaggt ctcatgatca
    18541 atcatgaacg ttctgaaatc cgtattgaca ttcggactcc tgtcttagct gacaaggaag
    18601 aactagtaga gttgcttaca agatgtgcac aaaactacca actccgctac gaagagtttg
    18661 actatctagc gcctctatac gtcgcaaaag acagtaaact cgttagcaca ctgatgcaaa
    18721 tctaccaaga aaagactggc gataacagtc ctgctatttc atccggtggt gccacttttg
    18781 ctcgcaccat gccaaattgt gtagccttcg gcgccttatt cccaggagcg aagcagacag
    18841 aacatcaggc aaatgaatgt gccgttctag aagatttgta ccgtgctatg gatatttatg
    18901 ccgaagccgt ctatcgactt gcaacttaat caggcaactg tttctacaaa aaaaatcgac
    18961 cgattaatga actgcacccc aaaagttaga cagaa
//
LOCUS       DBEJJV010000038        18873 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.038, whole genome shotgun sequence.
ACCESSION   DBEJJV010000038 DBEJJV010000000
VERSION     DBEJJV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.038"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            262..1821
                     /locus_tag="ACL3GT_001607"
     CDS             262..1821
                     /locus_tag="ACL3GT_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0517252.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(1970..2869)
                     /gene="htpX"
                     /locus_tag="ACL3GT_001608"
     CDS             complement(1970..2869)
                     /gene="htpX"
                     /locus_tag="ACL3GT_001608"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HGR0517253.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(2871..3431)
                     /locus_tag="ACL3GT_001609"
     CDS             complement(2871..3431)
                     /locus_tag="ACL3GT_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HGR0517254.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            3525..4238
                     /gene="rsmG"
                     /locus_tag="ACL3GT_001610"
     CDS             3525..4238
                     /gene="rsmG"
                     /locus_tag="ACL3GT_001610"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HGR0517255.1"
                     /translation="MKPETFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            4541..5824
                     /locus_tag="ACL3GT_001611"
     CDS             4541..5824
                     /locus_tag="ACL3GT_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HGR0517256.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6019..7590)
                     /gene="ffh"
                     /locus_tag="ACL3GT_001612"
     CDS             complement(6019..7590)
                     /gene="ffh"
                     /locus_tag="ACL3GT_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002902912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HGR0517257.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(7602..7934)
                     /locus_tag="ACL3GT_001613"
     CDS             complement(7602..7934)
                     /locus_tag="ACL3GT_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014637934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HGR0517258.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(8025..8402)
                     /locus_tag="ACL3GT_001614"
     CDS             complement(8025..8402)
                     /locus_tag="ACL3GT_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HGR0517259.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            8474..9778
                     /locus_tag="ACL3GT_001615"
     CDS             8474..9778
                     /locus_tag="ACL3GT_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HGR0517260.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            9791..10597
                     /gene="yidA"
                     /locus_tag="ACL3GT_001616"
     CDS             9791..10597
                     /gene="yidA"
                     /locus_tag="ACL3GT_001616"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HGR0517261.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            10640..11638
                     /locus_tag="ACL3GT_001617"
     CDS             10640..11638
                     /locus_tag="ACL3GT_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003712 - transcription coregulator
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HGR0517262.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNDLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(11804..11875)
                     /locus_tag="ACL3GT_001618"
     tRNA            complement(11804..11875)
                     /locus_tag="ACL3GT_001618"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11840..11842),aa:Arg,seq:cct)
     gene            complement(11917..12264)
                     /gene="rplS"
                     /locus_tag="ACL3GT_001619"
     CDS             complement(11917..12264)
                     /gene="rplS"
                     /locus_tag="ACL3GT_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HGR0517263.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(12383..12712)
                     /gene="crcB"
                     /locus_tag="ACL3GT_001620"
     CDS             complement(12383..12712)
                     /gene="crcB"
                     /locus_tag="ACL3GT_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0517264.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(12706..13080)
                     /gene="crcB"
                     /locus_tag="ACL3GT_001621"
     CDS             complement(12706..13080)
                     /gene="crcB"
                     /locus_tag="ACL3GT_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HGR0517265.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(13077..13343)
                     /locus_tag="ACL3GT_001622"
     CDS             complement(13077..13343)
                     /locus_tag="ACL3GT_001622"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HGR0517266.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(13459..13902)
                     /locus_tag="ACL3GT_001623"
     CDS             complement(13459..13902)
                     /locus_tag="ACL3GT_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HGR0517267.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            14006..14941
                     /locus_tag="ACL3GT_001624"
     CDS             14006..14941
                     /locus_tag="ACL3GT_001624"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HGR0517268.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            15037..15279
                     /locus_tag="ACL3GT_001625"
     CDS             15037..15279
                     /locus_tag="ACL3GT_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HGR0517269.1"
                     /translation="MKKDIHPEYRPVVFMDTTTGYQFLSGSTKRSNETVEFEGETYPL
                     IRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(15336..15554)
                     /locus_tag="ACL3GT_001626"
     CDS             complement(15336..15554)
                     /locus_tag="ACL3GT_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517270.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(15551..16302)
                     /locus_tag="ACL3GT_001627"
                     /pseudo
     CDS             complement(15551..16302)
                     /locus_tag="ACL3GT_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            16639..17985
                     /gene="gdhA"
                     /locus_tag="ACL3GT_001628"
     CDS             16639..17985
                     /gene="gdhA"
                     /locus_tag="ACL3GT_001628"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HGR0517271.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(18491..18661)
                     /locus_tag="ACL3GT_001629"
     CDS             complement(18491..18661)
                     /locus_tag="ACL3GT_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517272.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(18674..>18873)
                     /locus_tag="ACL3GT_001630"
     CDS             complement(18674..>18873)
                     /locus_tag="ACL3GT_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0517273.1"
                     /translation="INEERITKYIQSQGCTQIIVAHRLSTIKDADVIFVMKGGKIVES
                     GNHKYLMDLGGEYYSLYTKRK"
BASE COUNT         5817 a         4027 c         3393 g         5636 t
ORIGIN      
        1 atggacctgt ttttggattt tagagcatag aatttccagt tttctgttga caaaatttcc
       61 ttaaaggtat aatataaaga tactaatact cggaggtaag ggagacatga acaactaagt
      121 ctatcaaata aagaaccttt atttagtaga tcttgttttt gtctcttttt gtgtgctctt
      181 ttatgctctt tttctggcat gttaatagag tttttttgac atagactttg ggctctacta
      241 ggtaaagtag agctttttgt tatgcactat cgacattcta gaaagggcaa tagtatgata
      301 aaaatcaatc acctgaccat cacacaaaac aaagatttac gagaccttgt ctctgaccta
      361 agcatgacca tacaagacgg ggaaaaggta gctattattg gcgaagaagg aaatggtaaa
      421 tcaaccttac ttaaaacttt aatgggggaa gatttgtctg atttcactat caagggagac
      481 atccaatctg actatcagtc actggcctac attcctcaaa aacttcccga ggagctgaaa
      541 aagaaaactt tacacgacta cttcttttta gattctattg atttagacta cagtatcctc
      601 tatcgtttgg cggaggaatt gcattttgat agcaatcgtt tcgcaagtga ccaagagatt
      661 ggcaatctat cagggggaga agctttgaaa attcagctta tccatgagtt agccaaaccc
      721 tttgagattc tatttttaga tgaaccttca aatgacctag accttgagac agttgattgg
      781 ctaaaaggcc agattcaaaa gaccaggcaa accgttattt tcatttccca tgatgaagac
      841 tttctttctg aaacggcaga cactattgtt cacttgcgac tggtcaaaca ccgtaaagaa
      901 gcggaaacgc tagtagagca tttagactat gatagctata gtgagcagag aaaggctaat
      961 tttgccaaac aaagtcagca agctgctaac aaccaaagag cctacgataa aaccatggaa
     1021 aaacatcgga gagttaagca aaatgtagaa actgcgcttc gagctaccaa agatagtact
     1081 gccggtcgcc tattggctaa aaagatgaaa actgtcctct cacaagaaaa acgctacgaa
     1141 aaggcagctc agtccatgac tcaaaaacca cttgaagagg aacaaatcca acttttcttt
     1201 tcagacatcc aaccattacc agcttctaaa gtcttagtcc aactggaaaa agaaaatttg
     1261 tccattgacg accgagtttt ggttcaaaaa ctacaactaa ctgtccgtgg ccaagaaaaa
     1321 atcggtatta tcgggccaaa tggtgttggg aaatcaactc tgttagccaa gttacagaga
     1381 cttctgaatg ataaaagaga gatttcactt ggttttatgc cacaagatta ccacaaaaaa
     1441 ctgcaattgg atttatcccc aatagcctat ctcagtaaaa ctggggaaaa agaggaacta
     1501 cagaaaatcc aatctcacct agctagtctc aatttcagtt atccagaaat gcagcatcaa
     1561 attcgctcct tatctggcgg acaacaggga aaactcctgc ttttggattt agtcctgcgc
     1621 aaaccaaact ttctcctgct ggatgaaccc acacgaaact tttctcccac ttctcaaccc
     1681 caaatcagaa aactctttgc cacttatcct ggcggtctca tcactgtttc gcatgaccgt
     1741 cgtttcttaa aagaagtctg ctcgatcatc tatcgcatga cagaacacgg tttgaagcta
     1801 gttaatttag aagatttata aatttgcaac atagcagata ggtggggcaa aaacacaatt
     1861 ttaggagaaa aagaagtaaa tcttcccata gtaaaacgca taatatcaag ttttcacacc
     1921 tgatattatg cgtttttcag attttaaaga cttttttcca gccttcattt tacatatgtt
     1981 ttaaacgttc aatccgttct gagataggtg ggtgggtata aaagagtttt tggaaccccc
     2041 cacctttctt gggatcattg atataaaggg cactgctagc atcatcgacg tggcgactca
     2101 taggtttgct attgtccaac ttatctaggg cattaatcat tccctgggga ttgcgagtca
     2161 gctcgacact agatgcatct gccagaaatt ccctctgacg agaaatagcg agctgaacca
     2221 aggttgcagc gagaggtgcc agtacaatag ctagtaggga aaccactagc ataatgattt
     2281 caagaccatt tccatctcgg tcatcatcac ttcgtctgcg acctgctcca ccccaccaca
     2341 tcatacgacc tgccatacta gaaagcatgg tgatagcact agcaagggca actgcaatag
     2401 tcgaaatacg gatatcataa ttacgaatat gactgacttc atgtcccata acagcttcta
     2461 gttcttcacg attcatgata gctagtagac ctgaagtcgc agcaacagcc gcattttgag
     2521 gattagaacc tgtcgcaaag gcatttaagg ctggatcatc aatgatgaaa acacggggca
     2581 taggaatctg agcgaccaga gccatatctt ccactacatg gtagaggtct ggtgccgttt
     2641 gctcatccac ctcacgcgct ccattcatgg acatgacaat ctctgtcgat tgaaaaatca
     2701 tagacaaagc gtagataaag ccgataatca gtgcgataac caaaccacca agtccagatc
     2761 ttataaagag ataaccaacc gcataaccaa caagagctaa gagtaggaaa aataccagca
     2821 acaaaatcca ggtttttcgt ttattgcttg caatttgatc aaacaacatc ttagtcacct
     2881 aaaccgctaa aatcaacttt aggaaccgac ttttcctctt caggtgtttg aaggaaatct
     2941 gccgctttaa atccaaacat tccagcgata atattgctcg ggaaagtttc taattttaca
     3001 ttgtagttgc tgacaacact gttatagagt tgacgagagt aagaaatttt attttctgtg
     3061 tttgtcaact cctcttgcaa tttaacaaag ttagcactag ctttcaaatc tggatagctt
     3121 tctgcaactg caaaaatacc tgaaacttga cgagtgaggg catcactggc tttcatagct
     3181 tctgctggtg aagtcgctgc cgccacttgg ttacgtagtt ctgccacctt ttcaagggta
     3241 gaaccttcat atttggcata accttttaca gtctcaatca agtttggcaa gaggtcattt
     3301 cgacgtttca actgaacatc aatctgactc caagcctcct tggtttgcat acgattttta
     3361 accaaaccgt tatagctaac aatcacaaaa ataacaataa gagcgataac tccaagaata
     3421 atccaagtca tgatataagt cctttctact tttagattag taccagtata tcaaattttt
     3481 aatgattgtg gtaaaataag atgatactaa agaaggaaat aactatgaaa ccagaaacat
     3541 tttacaactt gcttgccgag cagaatcttc cactttcgga ccagcaaaaa gaacaatttg
     3601 aacgttattt tgagctcttg gtcgagtgga atgagaagat taatttgacg gcgattacgg
     3661 acaaggaaga agtttatctc aaacattttt acgattcgat tgcacccatt cttcaaggtt
     3721 tgattcccaa tgaaactatc aaacttcttg atatcggggc tggggcagga tttcctagtc
     3781 taccaatgaa aattctctat ccggagttag atgtgaccat tattgattca ctcaataagc
     3841 gcatcaactt cctacaactc ttggctcaag aactggattt gaacggagtt catttctacc
     3901 acggacgtgc cgaagatttt gcccaagaca agaacttccg tgctcaatat gattttgtaa
     3961 cagctcgtgc ggttgcccgt atgcaggtcc tatctgaatt gactattccc taccttaagg
     4021 ttggtggcaa actattagca ctcaaggcta gcaatgcgcc tgaggagttg ttagaagcta
     4081 agaatgccct caatctcctt tttagtaagg tcgaagacaa tctcagctac gccctaccga
     4141 atagagatcc gcgctatatc acagtggtag aaaagaaaaa agaaacacca aataaatatc
     4201 cacgtaaggc tggtatgcca aataaacgcc cactttaaat tttttagtaa acaaatgttt
     4261 acaaaatcag cctcgctctt ttatttctag gctcgggaaa aaatgattta caaaatcagc
     4321 ctcgctcttt tatttctagg ctcgggaaaa aatgatttac aaaatcattt ttttctgcta
     4381 tactatccta agcaaaggtt tttaatgtca tcccgtgagg tgacgaagac gcagaaatat
     4441 ttgaaactct ttaaagtcta gattttagag aagtcttact ctgagggcct attgctgtaa
     4501 aataatgggc tcttttctga tgcccaaaag tgaggtttat atgaaacaag aatcaactgt
     4561 tgatttgtta ctagacgttg accaacgtcc ttcggatgga aaaggaattc tccttagctt
     4621 ccaacacgtt ttcgccatgt ttggtgcgac catcttggta ccattgattt tgggaatgcc
     4681 tgtatctgtt gccctttttg cttcaggtgt tggaacactc atctacatga ttgctactgg
     4741 ttttaaagtt ccagtttatc taggttcttc atttgccttt atcacagcta tgtcactggc
     4801 tatgaaagaa atgggggggg atgtatctgc tgcccaaaca ggggttatct tgactggttt
     4861 ggtctatgtc cttgttgcta ccagcatccg atttgtagga acaaaatgga ttgataaact
     4921 cttgccacca atcattatcg gtcctatgat catcgttatc ggtcttggac ttgcaggttc
     4981 agctgttacc aatgcaggtc ttgtagcaga cggaaattgg aaaaatgctc tggtagccgt
     5041 tgttactttc ctaattgctg cctttatcaa tacaaaagga aaaggcttcc tacgaatcat
     5101 tccattcctc tttgccatta tcggtggtta ccttttcgca ctaactcttg gcttggttga
     5161 ctttacacca gttcttaaag ccaactggtt cgaaattcct ggtttctact tgccatttag
     5221 cacaggtggt gcctttaaag agtacaatct ttactttggt ccagaagcca tcgctatctt
     5281 gccaatcgct atcgtaacaa tttctgaaca tatcggagac catactgttt tgggtcaaat
     5341 ctgtggccgt caattcttaa aagaaccagg tcttcaccgt actcttattg gtgacggtat
     5401 cgcaacttct gtttctgcct tccttggtgg accagccaat acaacttacg gagaaaatac
     5461 aggggttatc ggtatgactc gtatcgcttc tgtctcagtt atccgtaacg ctgccttcat
     5521 cgcgattgcc ctcagcttcc ttggtaaatt cactgccttg atttcaacta ttccaaacgc
     5581 tgtacttggt ggtatgtcaa tccttctcta tggggttatc gccagcaatg gtttgaaagt
     5641 cttgattaaa gaacgtgttg atttcgctca aatgcgaaac ctcatcatcg caagtgctat
     5701 gttggttctt ggacttggag gagctatcct taaacttggt ccagttacac tttcaggtac
     5761 tgccctttca gccatgacag gaatcatctt gaacttgatc ttgccatacg aaaataaaga
     5821 ctaagagtct aaatacacct aatccactca gacagctgag tggatttttc gtatatcata
     5881 ataaaagtgt cttaacaaaa ttattaaaat caaaaaacgt ataatatcag atattctaaa
     5941 accttgatac tgtacgtttt atcatagaaa tttttacttt attttctcat caaatgagat
     6001 ttgcatcaat ctcttgtctt acttgcgttt cttcttcgct ttcttcattt tgttagccat
     6061 acgtttcatg gactgtttca tggcaaattc accaatttta cctttcaaac cgccaccaaa
     6121 catctggctc atatctggca ttcctgctcc tccgagagct gataagtcag gcataccgcc
     6181 ttgtcccatc attccttcaa gggcagacat atccattcct cccatatttg gcatattttt
     6241 aggaaggtta tttggattaa tccccatttg cttcatcatt ttattcatat ccccagacat
     6301 aacaccctgc atgagctgtt tagcctggtt aaagtccttg ataaatttat tgacttcgac
     6361 gaatgtattt ccagaaccag cagcaatacg acggcgacgg cttggattta acaaatctgg
     6421 gttttcacgt tcttcaggtg tcatcgaaga cacaatggca cgtttacgag caatctggcg
     6481 ttcatccacc ttcatgtttt gaagtgctgg attgttggcc atacctggaa tcatcttgag
     6541 caagtcttcc atcggcccca tattttgcac ctgatctaat tgatcgatga aatcattaaa
     6601 atcaaaggtg ttttcgcgca tcttctcagc catttcaagg gctttttgtt catcgtattc
     6661 ctgagaagct ttctcaatca aagtgagcat atcccccatg ccaaggatac ggctagacat
     6721 acggtctggg tggaaggttt cgatatctgt aattttttca cctgtaccag tgaacttgat
     6781 tggttttcca gtgatgtgac gaaccgatag agccgcacca ccacgagtat cgccatcaat
     6841 cttggtaagg atgaccccag tcacttccaa ctgagcatta aactcacgcg caacattggc
     6901 tgcttcctga ccaatcatgg catcaacgac gaggagaatt tcatttggtt gagccaatgc
     6961 tttcacatca cgaagctcat tcatgaggag ctcatcaatt tgcaaacgac ccgcagtatc
     7021 aatcaagaca tagtcgttat gattagtttg ggcttgctcc aaaccttgac gtacaatctc
     7081 aacagctggt acttctgttc caagtgcaaa gacaggcaca tcaatctgtt gtcccaaagt
     7141 cttaagctgg tcaatggcag ctggacgata aatatccgcc gcaatcatca aaggacgagc
     7201 attttcttct ttcttgagtt tgttggccaa tttaccagca aaggttgttt taccagcccc
     7261 ttgtaaacca accatcatga tgatggttgg aatcttaggt gacttgataa tttctgccgt
     7321 atcagaacct aaaacggctg tcagttcctc atcaacgatt ttaataatct gttgcgcagg
     7381 attaagtgta tcaatgacct catgcccgac tgcacgctca cgaactttct tgataaagtc
     7441 ctttacaaca ggcaaagcaa cgtcggcctc aagcaaggcc aagcgaattt ctttggttgc
     7501 ctcttggaca tcagattcag agatttttcc ttttttacgt agacttttaa agacgttctg
     7561 caaacgttct gttaaacttt caaatgccat ttttcttcct cttattctct attatcaatg
     7621 cttgttaaaa tttctatctg ctcctgcaga aagttatcct tgggatagcg ctccaaaatc
     7681 tgatcaaaaa tctgactgcg gacaatatag tccgagtaca tgtgcaattt catctcataa
     7741 tcttccagaa tcttttctgt tcgcttgata ttgtcataga cagcctgacg actgacaccg
     7801 aactcctcgg caatttcagc aaggctgtaa tcatcagcgt agtagagctc gatataattc
     7861 atttgcttat ctgtcaaaag cgccgcataa aattcaaaga gcgcattcat acgattggtt
     7921 ttttcgattt ccataacttt tattatacca aaaattagcc taatctacca cactaggaag
     7981 ccgatccaag aagatagata gctaaatttg aaaaagacat aagcctagcc ccaagtaatt
     8041 tccaattgat agctggcaaa gggatgtccc tcttgatttt gtagttgata atctagttca
     8101 atcttttgcc catccacttg ataacgattc gtttggataa taaactcctg catacccata
     8161 ggtgtgggaa tataggctaa actatcacta tcctttagaa agcgcataat ggtcttggga
     8221 ttggaaaatc gactcatcac aagttcttga ccatgaaatt taatcactac tttttccttt
     8281 tcctcattat agaaaagcag gtagctataa tctccttttt catgcacttc cacatcataa
     8341 agctggtcaa tcacttccaa ctgctcatca aactgaattg tatttcgcat ccgaatcttc
     8401 acatcaggcc ctctttcttg tctcttgtcc tactatttta ccaaaaagag caggattttg
     8461 ctataatggt catatgaacg aaaaagtatt ccgtgaccct gttcacaact acatccatgt
     8521 caataatcaa atcatctatg acttgattaa tacaaaagaa tttcagcgtt tgcgccggat
     8581 caaacaactg ggaacttcca gttatacctt ccacggtgga gaacacagtc gcttctctca
     8641 ctgtctagga gtctatgaaa ttgcacgacg catcacagag attttcgaag aaaaatatcc
     8701 tgaggaatgg aatcctgccg agtctctctt gaccatgacc gctgctctcc tacacgacct
     8761 tgggcatggt gcctactccc atacttttga aaatctcttt gatacagacc atgaagccat
     8821 tactcaggag attattcaaa atcctgagac agagattcac caagtcctgc tacaagtggc
     8881 acctgatttc ccagaaaagg tggccagtgt cattgaccat acctatccta ataagcaggt
     8941 cgtgcagctc atttctagtc agattgacgc agatcgcatg gactatctct tgcgcgactc
     9001 ctattttaca ggagcatcct atggggaatt tgacctgact cgaatcctcc gagtcattcg
     9061 tcctatcgaa aatggtatcg cctttcagcg caatggcatg cacgccatcg aagactacgt
     9121 cctcagtcgc taccagatgt acatgcaggt ttatttccac cccgcaacac gcgccatgga
     9181 agttctccta cagaatcttc tcaaacgcgc caaggaactc tatcctgagg acaaggattt
     9241 ctttgcccga acttctccac acctcctgcc tttcttcgaa aaaaatgtga ccttgactga
     9301 ctatctggct ctggatgatg gcgtgatgaa tacctacttc cagctttgga tgaccagtcc
     9361 tgacaagatt cttgcagatt tatcgcatcg ctttgtcaac cgcaaggtct ttaaatccat
     9421 taccttttca caagaagacc aagaccaact cgctagcatg agaaaattgg ttgaggacat
     9481 cggctttgat cccgactact atactgccat tcataagaac tttgacctcc cttatgatat
     9541 ttaccgtccc gaatctgaaa atccaaggac acagattgag attttacaaa aaaatggaga
     9601 actggcagaa ctctctagcc tgtcccctat cgtccaatcc cttgctggaa gtcgccacgg
     9661 agataatcgc ttttatttcc cgaaagaaat gttagaccaa aacagcatct tcgcaagcat
     9721 cacccagcaa tttttacact tgattgagaa cgatcatttt accccaaata aaaactaaaa
     9781 gaggaaattt atgagtatta aactaatcgc cgtcgatatt gacggaaccc tagtcaacag
     9841 ccaaaaggaa atcactcctg aagtcttttc tgccatccaa gatgccaaag aagctggtgt
     9901 caaagtcgtg attgcaactg gccgccccat cgcaggtgtt gccaaacttc tggacgactt
     9961 gcagttgaga gaccaaggtg actatgtggt gaccttcaat ggtgcccttg tccaagaaac
    10021 tgctactggc catgagatta tcagcgaatc cttgacctat gaggattatc tggatatgga
    10081 attcctcagt cgcaagctcg gtgtccacat gcatgccatt accaaggacg gtatctatac
    10141 tgcaaatcgc aatatcggaa catacactgt acacgaatca accctcgtca gcatgcctat
    10201 cttctaccgt acccctgaag aaatggctgg caaggaaatt gtcaagtgta tgttcatcga
    10261 tgaaccagaa attctcgatg ctgcgattga aaaaatacca gccgaatttt acgagcacta
    10321 ctctatcaac aaatctgctc ctttctacct cgaactcctt aaaaagaatg tagacaaggg
    10381 ttcagctatt actcacttgg ctgaaaaact cggattgacc aaagatgaaa ccatggcaat
    10441 cggtgacgaa gaaaatgacc gtgccatgct ggaagtcgtt ggaaaccccg ttgtcatgga
    10501 aaatggaaat ccagaaatca aaaaaatcgc caaatacatc actaaaacaa atgacgaatc
    10561 cggcgttgcc cacgccatcc gaacatgggt actgtaaaag tatcattttt caataagaat
    10621 tgattagcaa taaaatccaa tgaatttttt tagcaaacta tttaatttaa aacaaaataa
    10681 tcataataga gacacaaatt ctgattgtaa caatttttac ctaaacgatt tagaatgtgg
    10741 ccttactcct gggcaactca tactcataga ttggactcaa aaaacaggga gaaattataa
    10801 tttcccaaga tattttaaat actctcttca aattgaccct gaatctacac acaatcaatt
    10861 atacaaatta ggatacttca ctaaaaataa gactttatca tatcttacag tagtagaatt
    10921 aaaaactata ttatctaaac ataatttagc tacttctgga aaaaaagcag aattaattac
    10981 aagaataatt aataatgtta acattgacaa tttagatatt ccgttcgaat ttaaactaac
    11041 aaaagaagca caaaatctta ttatcgaaca tagtgactat atcaaagcat actatgataa
    11101 agacataact atggaagatt attgtaaaga aaaaaacaat atctctttta aagcaacttt
    11161 tggtgatata aaatggagtc tcttaaataa acaagctcat aggaatactg tatcaggaga
    11221 ttttggatgc ttatctaaca cacgaaaggc tcagggaaga catttggaac aagaaggtaa
    11281 tattaaacat gctttaatat attacataga atctttgata attactattt caggattaga
    11341 aaacaatttt tcagccactg attatccagt atattatccc gattcgatac ctgactactc
    11401 actaaaacat attcaaacat taatggaatc attatctgat gacgattatg attttgcttt
    11461 tgatgaagca ttatttcgct tctcaatttt gaatgcaaat cattttttat ctaaggaaga
    11521 tattgactat ttaagagtta atttacctcg ttccactgct gaagaaataa acaattactt
    11581 aaagaaatat gaatgttata gtcctttaaa taatttagaa cttgacgatt ttgaataaat
    11641 tgactataca aacatttata tactcgatat agtctcaatt ttatctgatg attgcccaaa
    11701 tttttcaata ataaaacgca taatattatg gagacaatcc cctatattat gcgttctttt
    11761 aatatcaaag actttttgac aaacttcttc gatatctaat tactgccccc tgcaggaatc
    11821 gaacctgcaa ctactcctta ggagggagtt gttatatcca ttgaactaag ggagctagat
    11881 aaaaactctg ctgaaaagca gagtttttta gtcgaattaa cgacggattt ctttgatacg
    11941 agctgcctta ccttgaagag cacgcaagta gtacaatttc gcacgacgta ctttaccgta
    12001 acgaacaact tcgatttttt caacacgtgg agtgtggatt gggaagatac gctcaacacc
    12061 tacaccgtta gagattttac gaactgtgta gttttctgag attccagcac ctttacgtgc
    12121 gataacaaca ccttcaaaaa tctggatacg ttcacggtta ccttcgacaa ctttcgcatg
    12181 tacacgaaca gtgtcaccag gacggaatga tgggatatct gtacgaagtt gaccttcagt
    12241 caagctttgg attaatggat tcattttatt ctcctatctt tgtcaatctt gaggaatctt
    12301 cctcagcgga taaactgtat ttttgtgcgt ccattacaca caagatatag tttaccaaat
    12361 ttctaaaaaa aagtaaagaa atttatagca aaattcctaa aaaaatcgca accaaaccac
    12421 ctatgtaagt caaagtcagg taagaataaa agaccttctt atcacttagc agtctttgaa
    12481 gttcgtcatt caaggtcgaa aaagttgtta aaccgccaca aaatcctgtt gctagaatag
    12541 catatacttc cttagactct acatgattgt agaatactcc aattaaaaaa caacctaaaa
    12601 gattagctat gagcgttccg agtggcaatt tagaagcttg attatagcga gaaaagaaat
    12661 accgtacgag tgctcccaag ccacaggcga ttgcaagata gacgattacc atttcttcct
    12721 ccccaaatag taagctaaaa gcaggcctcc accgatactc aaaagcaaat acagtatcaa
    12781 actaagataa cgccctgtat caagcagctt cacagtatca agcattaggc tggaaaaagt
    12841 tgttaaacct ccgcaaaaac ccgtccccag tgctaaaatc aagcccttac tagtcccctt
    12901 atagaccaga tagcccttga caagataaat caagcagaaa attcccagat agttgacaaa
    12961 gagagtgccc caagggaaat ctggactggc tggtaaccaa gtggaaacta ggtagcggac
    13021 aagtccgccc aacatagcag ctagaaaaat ccctagcgga taaaattgtt cttttttcat
    13081 ttgatatttt gatcctgata atcacgcgaa cgtttgagta tgtccgaaaa agtcgcgaca
    13141 atagtctcct gatagcgctt gtcctctaca cgacttctaa ccttttcaaa aataactgct
    13201 tctctcttag tatctaaaat cggtttccct gaagccttct tataagcgac aactccttca
    13261 actaagtgca ttcgttcttc taacagtttg acaatttggt cgtcgatttg atcgatttct
    13321 tgacgaataa tatctaaatc catacagtct cctcctttat ttgaattatt gtatcaaaaa
    13381 gccatcaatt aggctagtaa aatcccaact ctcgataaga aaaatgcact gattgattac
    13441 atcagcgcac ttttatgctt atcctacttt agcagccaat tcttctgcga attgttccaa
    13501 gcgttcaata tcttcttcct cggcagaaag atcaacttta acacactctg aacctttttc
    13561 tgctcctgtt gacacaaaga cacggtcaaa gtcatcaaca gccttacaaa attcatcgta
    13621 gaaggtatct cctgagccga ccactccgta gattttgcca ttcaagttga gatctgctag
    13681 gtcttcgtag aagtccatca tctcatctgg caattcacca tcaccataag tataggtcgc
    13741 aacgatagcg atgtctgctt ccaagaagtc tgaagcgtca acagttgtac attcatcaac
    13801 atcaacatcc aagcccaagt cacgtaattt gtctgctaca atatctgcaa tttcttcggt
    13861 attaccggtc atactggcaa atacaatttt tgctaatgcc atatcgtcct cctcaattta
    13921 tctttctcca ttatatcaca tctttttcat tttaaaaata aaaattcttg tgctacaatg
    13981 aaatgagaaa gaattgaggt tatttatgga gatttgccaa caaattttag aaaaaattaa
    14041 agaatacgac accattatca ttcatcgtca tatgaaacca gaccctgatg ccttgggaag
    14101 tcaggtggga ttgaaagcct tgctagaaca tcatttccca gaaaaaacca tcaaagccgt
    14161 cggttttgat gaaccaactc ttacttggat ggctgagatg gatcttgttg aagatagagc
    14221 ctaccaaggc gcacttgtca tcgtctgtga tacagctaat actgctcgta tcgatgataa
    14281 gcgctatagt caaggtgatt ttctcattaa gattgaccac catccaaatg atgatgtata
    14341 cggtgacctg tcttgggtcg atactagttc aagtagcgct agcgagatga ttaccctatt
    14401 tgcccaaaca acccaactag ccttggcaga tcgcgatgct gagttgctct ttgcaggaat
    14461 tgtcggtgat acaggtcgct tcctctaccc ttctaccact gcacggactc ttcgcctggc
    14521 tgcttatttg agagaacata actttgactt tgcggctctc actcgcaaaa tggacactat
    14581 gagctacaaa attgctaaac tgcaaggcta catctacgac catctggaag tggatgaaaa
    14641 tggtgctgct cgcgttatcc tgagtcagaa aatcttgaaa caatacaata taaccgatgc
    14701 tgaaactgcg gccattgtag gtgcacctgg acgcattgac agagtgagtc tctggggaat
    14761 ttttgtcgaa caggctgatg gccactaccg agttcgctta cgcagtaaag tccatcctat
    14821 caatgaaatt gccaaggagc atgatggtgg aggccaccct ctagcaagtg gtgctaattc
    14881 ctatagccta gaagaaaacg aaatcatcta ccaaaagtta aaaaacttgc ttaaaaactg
    14941 ataaaatact tgccaaactt ttcagaatct gatagactag tatagtaaca atctatggct
    15001 cgcaaagaga ccatggcaga aaggaaatat tgcaaaatga aaaaagatat ccatccagaa
    15061 tatcgcccag ttgtcttcat ggacacaact actggttacc aattccttag cggttcaaca
    15121 aaacgctcta acgaaacagt tgagttcgaa ggcgaaactt acccattgat ccgtgtggaa
    15181 atttcatcag actcacaccc attctacact ggacgtcaaa agttcactca agcagatgga
    15241 cgcgtggatc gtttcaacaa aaaatacggt ctcaaataat gataagagaa cagttttggc
    15301 tgttcttttt tgtttcttga aatcaactgc tgttttcatg ttccagactc atctgtaggt
    15361 tcgatttcca tgctactagg caggaaggaa atagctgttt caacacgtcc ataatgagct
    15421 atactattgt cacgaaccac actttcattg atggtccaag tggaattcat tttcttaaaa
    15481 gcttctcgga ctttttccaa atctttggag gcaatggcct gctctaaggt ttcaaaacga
    15541 ggacttatac tcatctgctt tcaaaaagca ttctagtcca tctccgatta ccgatggact
    15601 ttatcacctc cttctccagt ccttgtatga catcttgaag ttgattcatg acatcttcca
    15661 aagttcgaaa ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa
    15721 tgggttcatc tctggtgtgt atggaggaat aaaggtaaaa tcaatattag tcggaatatt
    15781 taaggtactt gatttatgcc atatagcatt gtccataacg agtaaaagga taagcttgtg
    15841 aaagctcttc taaaaaggcg ttcatccaca ctccttttta taaacctgaa ataaggcatc
    15901 aattgtaaca aattctcctg cctctgtagc cttcaaatga cgggcaagaa aggctttctc
    15961 ttcctcaact gtcatatatg catggttacg accaccacgt gtttcttgaa ggagagagtc
    16021 gagtccgaac tcctcatatt tttttacgtt tcgccaaatc gttgtttgat tacagtctaa
    16081 aagctctata atctctttat aagatttgcc catcagacga aatatagtag attgaaacta
    16141 gaatagtaca cctctacttc taaaacattg ttagaaatcg atttgtcctg ttcttgtttc
    16201 attttactat agaacgattt gaaggcgttt ataatattta gctgtacgag agtcttttaa
    16261 aagtgttttg atggtttgga tttcttcttt agttgatttc atattactat tatataatgc
    16321 tttttgattt tagtctggta taaatattgc tttcctccaa aatggtcata gttttactgg
    16381 caaatctaac atatcacgga taaattaaca agtgatttct gaattgctaa acattttctt
    16441 ttcttatagc atactttaag attttgtctt tgagaaagat atttccaaga aaaacgttcg
    16501 tttttttatc tattttcaaa aaaaccaaaa aactgaattg aaagaatttt tagaaaattt
    16561 ctgttttttc tttacagtga aaaaaaattc tgctataatg tcttatgtaa taaaatatga
    16621 caataaaagg agaacgatat gacatctgct aaagaatata tccaaagcgt gtttgaaact
    16681 gtgaaagctc gtaacgggca cgaggctgaa ttcctccaag ctgttgaaga atttttcaac
    16741 actttagaac ctgtatttga aaaacaccct gagtatatcg aagaaaatat cttggcacgt
    16801 attactgagc ctgagcgcgt ggtttctttc cgtgttcctt gggttgaccg tgatggaaaa
    16861 attcaagtaa accgtggtta ccgtgttcaa ttcaactcag ctgttggacc atacaaaggt
    16921 ggacttcgtt tccacccaac tgtaaaccaa gggatcttga aattcctcgg atttgaacaa
    16981 atctttaaaa atgtcttgac tggacttcct atcggtggag gtaaaggtgg atcagacttc
    17041 gatcctaaag gtaaaacaga tgctgaagtg atgcgcttct gccaaagctt catgactgaa
    17101 ttgcaaaaac acatcggacc atcacttgac gtacctgctg gtgatatcgg tgttggtgga
    17161 cgtgaaattg gttaccttta cggtcaatac aaacgtctta accaatttga tgctggtgtc
    17221 ttgactggta aacctcttgg atttggtggt agcttgattc gtccagaagc aactggttac
    17281 ggtttggttt actatactga agaaatgctc aaagctaacg gtaacagctt tgctggtaag
    17341 aaagtcgtta tttcaggttc tggtaacgtt gctcaatatg ctcttcaaaa agcaactgaa
    17401 ctcggtgcaa ctgttatttc tgtttctgac tcaaatggtt atgtcatcga tgaaaatggt
    17461 atcgacttcg atcttttggt tgatgttaaa gaaaaacgtc gtgctcgttt gactgagtat
    17521 gcagctgaaa aagcaactgc aacctaccac gaaggtactg tatggactta cgctggaaac
    17581 tatgacattg ctcttccatg tgccactcaa aacgaaatca acggtgaagc agctaaacgt
    17641 ttggttgctc aaggcgttat ctgtgtatct gaaggtgcca acatgccgag cgaccttgat
    17701 gccatcaaag tttacaaaga aaatggtatc ttctacggac ctgcaaaagc tgccaacgct
    17761 ggtggtgtag ccgtttcagc tcttgaaatg agccaaaaca gtcttcgcct ctcatggact
    17821 cgtgaagaag ttgatggccg tctcaaagac atcatgacaa acatcttcaa cacagctaaa
    17881 acgacttcag aaacatacgg tcttgataaa gactaccttg caggagctaa cattgctgcc
    17941 tttgaaaatg tagcaaatgc catgattgca caaggtattg tttaagattt atttactcaa
    18001 tcctcaatca ctacgattgg ggatttttag cttgaattaa aaaattggaa aatctaatta
    18061 aataaaatga aatgaaataa aaactgaaca aattgattgc ggaattcaaa ccaatttcta
    18121 acatatttct agaaattaat ttgacttttc taatcgattt gttcatatct tatttcaatt
    18181 tactatactt acttgaccct ttttatactc aatgaaaatc aaagagcaaa ctaggaagcg
    18241 agccgcaggc tgtacttgag tacggtaaag caaagctgac gtggtttgaa gagattttca
    18301 aagagtatta aacaaaaaga aaaaccgcta ctcctaagaa tagcgattta atcatgtttt
    18361 taagctacta ctgtagttgc tctattattt aagtgttatg aataacttca atatctttaa
    18421 agctttttgt tagatttata atttcaacta tagccatctc tactccttag tttacagcaa
    18481 aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat
    18541 tcaacaagcc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaacacta
    18601 ttccaatcat cactcctagt gaggctgttg ttaaaattac atattcattt tctttcttca
    18661 ttttctttac acctcatttc ctttttgtat ataagctgta gtactctcca ccaagatcca
    18721 ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcattaca aaaataacat
    18781 ccgcatcctt aatcgttgac aatctatgag ctacaattat ttgagtacag ccctgacttt
    18841 gtatatactt tgttattctt tcctcattaa tag
//
LOCUS       DBEJJV010000039        18678 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.039, whole genome shotgun sequence.
ACCESSION   DBEJJV010000039 DBEJJV010000000
VERSION     DBEJJV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18678
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.039"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..863)
                     /gene="lytB"
                     /locus_tag="ACL3GT_001631"
     CDS             complement(<1..863)
                     /gene="lytB"
                     /locus_tag="ACL3GT_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HGR0517274.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGG"
     gene            complement(905..1843)
                     /locus_tag="ACL3GT_001632"
     CDS             complement(905..1843)
                     /locus_tag="ACL3GT_001632"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HGR0517275.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKVTNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1854..2654)
                     /locus_tag="ACL3GT_001633"
     CDS             complement(1854..2654)
                     /locus_tag="ACL3GT_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HGR0517276.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2904..3284)
                     /locus_tag="ACL3GT_001634"
     CDS             complement(2904..3284)
                     /locus_tag="ACL3GT_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HGR0517277.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3342..3701)
                     /gene="rplT"
                     /locus_tag="ACL3GT_001635"
     CDS             complement(3342..3701)
                     /gene="rplT"
                     /locus_tag="ACL3GT_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HGR0517278.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3753..3953)
                     /gene="rpmI"
                     /locus_tag="ACL3GT_001636"
     CDS             complement(3753..3953)
                     /gene="rpmI"
                     /locus_tag="ACL3GT_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HGR0517279.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3986..4516)
                     /gene="infC"
                     /locus_tag="ACL3GT_001637"
     CDS             complement(3986..4516)
                     /gene="infC"
                     /locus_tag="ACL3GT_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HGR0517280.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4532..4663)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4823..6004)
                     /locus_tag="ACL3GT_001638"
     CDS             complement(4823..6004)
                     /locus_tag="ACL3GT_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0517281.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIVLALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKMQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQKIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     gene            complement(6008..6595)
                     /locus_tag="ACL3GT_001639"
     CDS             complement(6008..6595)
                     /locus_tag="ACL3GT_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0517282.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6628..6852)
                     /locus_tag="ACL3GT_001640"
     CDS             complement(6628..6852)
                     /locus_tag="ACL3GT_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517283.1"
                     /translation="MIIGLFQSSISAVTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSW
                     SRYDSYSEYPVGSGWNYGRYEIINYYSGGY"
     gene            complement(6994..9234)
                     /locus_tag="ACL3GT_001641"
     CDS             complement(6994..9234)
                     /locus_tag="ACL3GT_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HGR0517284.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPLSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9218..9868)
                     /locus_tag="ACL3GT_001642"
     CDS             complement(9218..9868)
                     /locus_tag="ACL3GT_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HGR0517285.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            complement(9936..10505)
                     /locus_tag="ACL3GT_001643"
     CDS             complement(9936..10505)
                     /locus_tag="ACL3GT_001643"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0517286.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTPETNRAVIELAFEKIGMNKLVALYDKDNSASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10682..11793
                     /gene="ald"
                     /locus_tag="ACL3GT_001644"
                     /pseudo
     CDS             10682..11793
                     /gene="ald"
                     /locus_tag="ACL3GT_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003018852.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000286 - alanine dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0042853 - L-alanine catabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12094..12420)
                     /locus_tag="ACL3GT_001645"
                     /pseudo
     CDS             complement(12094..12420)
                     /locus_tag="ACL3GT_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12423..12923)
                     /locus_tag="ACL3GT_001646"
     CDS             complement(12423..12923)
                     /locus_tag="ACL3GT_001646"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0517287.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            12959..13138
                     /locus_tag="ACL3GT_001647"
     CDS             12959..13138
                     /locus_tag="ACL3GT_001647"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517288.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(13116..14084)
                     /locus_tag="ACL3GT_001648"
     CDS             complement(13116..14084)
                     /locus_tag="ACL3GT_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HGR0517289.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14170..14385)
                     /locus_tag="ACL3GT_001649"
     CDS             complement(14170..14385)
                     /locus_tag="ACL3GT_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HGR0517290.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14394..15248)
                     /gene="cvfB"
                     /locus_tag="ACL3GT_001650"
     CDS             complement(14394..15248)
                     /gene="cvfB"
                     /locus_tag="ACL3GT_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HGR0517291.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15308..15865)
                     /gene="frr"
                     /locus_tag="ACL3GT_001651"
     CDS             complement(15308..15865)
                     /gene="frr"
                     /locus_tag="ACL3GT_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HGR0517292.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15874..16611)
                     /gene="pyrH"
                     /locus_tag="ACL3GT_001652"
     CDS             complement(15874..16611)
                     /gene="pyrH"
                     /locus_tag="ACL3GT_001652"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HGR0517293.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16695..18029)
                     /gene="trmFO"
                     /locus_tag="ACL3GT_001653"
     CDS             complement(16695..18029)
                     /gene="trmFO"
                     /locus_tag="ACL3GT_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HGR0517294.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18275..18547)
                     /locus_tag="ACL3GT_001654"
     CDS             complement(18275..18547)
                     /locus_tag="ACL3GT_001654"
                     /inference="COORDINATES: protein motif:HMM:NF036719.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HGR0517295.1"
                     /translation="MFTCFIIHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSG
                     KIKYHEDSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            18524..>18678
                     /locus_tag="ACL3GT_001655"
     CDS             18524..>18678
                     /locus_tag="ACL3GT_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGR0517296.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSL"
BASE COUNT         5394 a         4227 c         3450 g         5607 t
ORIGIN      
        1 ccaccggatt tgaagtagta ccaagcttga ctatgagaat cgtagaccca ttctttttca
       61 gctattttcc catcaaactt gaggtaaaac caagattcct tatcccaaat ccattcattg
      121 gctgccatgt agccaccgga ttttagataa taatagtgac cattctcgaa aatccattct
      181 ttatcagcat agtttccatt ttctttgatg taaaaccaag attggtattg tttgtcaaaa
      241 agccaacctt gctgtacttt ggcaccacta gcattcacat aagcttgatt aatccactga
      301 cttgtcagta gataaccacc ggatttgaaa taatagtcct tccctttaat ttggagccat
      361 tctttctctg cgtgctgtcc atctgctttg atataaaacc aagcatcgta ttgagaatca
      421 tagacccagt cttctattac tttggcacct gttgcaccaa cataggaagt tcctacccaa
      481 gcatttcttt tcatctttcc atcttggtca agataataaa aggctccctt gtcttctacc
      541 cattctgatt tggccatata gccaccagat ttgaggtaaa aatagtcgtc accttgcttt
      601 agccattcat tttcagcata gttagcatct gcttttatat agaaccaaga ttgataatga
      661 gtatcaaaaa cccactcatt cgctgcttga ctgccatctt ctttcagata ctgttttcct
      721 tgccaagtac catcactagc cattgcaccc tctggactag ctaagaaaaa tagcagagct
      781 aaaaaaataa atcttacttt cttcattaac cttcttcctc tgttcttatt tattttattg
      841 taccaaaatt ctcctaaatt catattacaa actaataaaa aatcaagaac agattgattg
      901 cagtttacct cagagactct tttacttcct gacggagttc ttccagactg ctaataccgt
      961 atttatccat gacttttggt aaattttcga tgatgtcagg gcaggcataa ggattggtaa
     1021 agttagctgt tccaactccg atagcagatg ccccagccag atacatttct agggcagctt
     1081 cagccgaatc cactcccccc attccaatga taggcaggtc tgttgtttgg gctacttggc
     1141 ggatgagttt gagggctact ggaaagactg ctggacctga cattccacct gttccattgg
     1201 ccaagattgg ttttctggtt ttgaggtcaa agcgcattcc aaccagagta ttgatcatgg
     1261 tcaagccact tgctcccgca tcttctgcag cttttgcgac agtaacgata tcggtcacac
     1321 tcggggttaa tttgacataa actggcactt ctgaggcttc cacagctgct ttcaccacat
     1381 cataagccaa atctggatct tgaccaatca aaagtccatg attacagtgg tcaacattgg
     1441 gacaagaaat attgagctcg atagctttta cattagttac cttggaaatc ccatgagaaa
     1501 cagctgcata ctcttgtttt gaaaaaccag ctacattggc aataatagga agatttggat
     1561 attctctttc cagccaaggt agcttttcag ccaaaacaac ctctaaacca ggattttgca
     1621 agccaattgc attgagcata ccagcaggcg tctctgccac tcttggagtt ggatttccaa
     1681 aacgtggttc aagggttgtc gccttgatca taatagaacc taaaaggtct aaatcatagt
     1741 acttggcata ctcttgtcca aagccaaaac agcctgatgc tggaataatc ggatttttca
     1801 aatccaaacc aggtagagaa acttgtaatc gatttgtagt cataattttc tccttataat
     1861 acaactgttc ctgtgcggaa aacaggacca tcttcacaga cgcgttggct gaccgtctcg
     1921 ctttctggta cttttagaac acaggcatag caagctccca tcccacaagc catacgagat
     1981 tccagagata aataggctct tgggtgatca tcaaaggttt gattgatata cttcatcatt
     2041 cctggagccc cacacgagta aacagcatca aactgactgt ctaaatcatt gataacaacg
     2101 gaaacatttc ccttgatgcc ataagaacca tcatctgtcg ttacaaagac ctgaccatac
     2161 tgagccaatt ccgttttcaa aataacagca tccttattag caaaaccgag gactgtcact
     2221 actttcactc cacgttcatg caattccttg gccacctcaa gcaagggtgg aacaccaatc
     2281 ccaccaccaa caaggagaac ctgattctgc tcatcaaggt cagacaagtc aaaaccattt
     2341 ccctgaggcc ccatcacatc aagagtgtct ccctgactta aggttgaaaa aattgcagtc
     2401 ccagctccct caatccgata aatgaggtga cactgcttgt ttgccttgtc aatagacgaa
     2461 attgaaatag gacgacgtaa gagatgggca tcgtctggta cacgcagatg aagaaattgg
     2521 cctgctcgca tggcttcaac catttctcct tctaggacta attcaaagat tgctggcgcg
     2581 atttcctctt gtgcaaccac cttcatggtt tccaaccgaa tgacacccaa acgcttctta
     2641 catgtgagat tcataacttt tcctccttaa attttaaggg gaccagataa agaaaagacc
     2701 ttgctagtgc aaggcctcag ttaaaatcgt acaacacaag agagcacact caaaaggtct
     2761 cctctagaaa cttgcactat tcttttatct gacaccttgt gagtctctct ggactcccct
     2821 taaaggttga atttttatta gtatactctt tcagctaaaa aaagtcaagt agaaaacgaa
     2881 tattctactt aacttgcacg aaattatttt tcacgaatga cttcgacctt atatccatca
     2941 gggtctttaa caaagtaata gtttggtgta gttcctggta gaccatttgg ctcagtcact
     3001 tcatagcctt ttgcactgtg ttcttgatga agtgcctcaa gatcaggtgt actgagggcg
     3061 atatgggcaa acccatcacc aaccacatac ggaccgtgat cgtagttata agtcaactcc
     3121 aactcataat catcaccctc aagacctaga tagacaatcg tgaaggcatg gtctggaaaa
     3181 tctctgcgac gcaattcttt aaaaccaaaa gcatcttgat aaaatgcgat tgatttttca
     3241 agattttcta ctcgtaagca agtgtgtagc atttttgaag ccatatcttt ctcctttatt
     3301 tttaaaaaga ctggacaatc ctgttccagt ctcatcagtt gttatttacc aagttttgct
     3361 ttagctgcat ctgcaagagc tgtgaaagct actgcatcgt taacagccaa gtcagcaagc
     3421 attttacggt taacttcgat ctcagccaat ttcaaaccat gcatcaattg tgagtatgaa
     3481 agtccgttca tacgagccgc cgcattgata cgagtaatcc acaatttgcg gaagtcacgt
     3541 tttttctgac gacggtcacg gtatgcatag tagtaagagt tcattacttg ttcttttgca
     3601 gtacggaaca agatgtgttt agctccatag taaccttttg ctaatttaag aatacgttta
     3661 cgacgtttgc gtgatacaac gccaccttta acacgtgcca tgttttattt cctccaaata
     3721 ttttctagaa ttgtttactt acagtcaagc tattatttca agcgagtaag cattgctttg
     3781 atacgtttgt aatctcctga atgcaccata gatgctttac gaagatgacg acgttgtttc
     3841 ttagtttttc cgtggaaacg gtgagaagtg taagcacgga aacgtttaag tccaccagaa
     3901 cctgtacgtt tgaaacgttt agctgatgcg cggtgtgttt tttgttttgg catgattttt
     3961 tctcctttat ttaactttct gacaattatt ttttgtcagt cgctggcgcc aattgcatga
     4021 acatttgacg tccatccatt ttagcacgtt gttcgatgat ggcaatatct tgagttgctt
     4081 cagcaaactc ggctaaaact tttgcaccaa tctctttatg ggtaatcata cgacccttaa
     4141 agcgaataga taccttaact ttatttcctt tttcaaggaa cttacgtgca ttacgaagtt
     4201 ttgtatcaaa gtcacccttg tcaattgttg gacttagacg aacttctttc acagtaacaa
     4261 cgctttgttt tttacgttgt tctttttgct tcttctggta ctcaaatttg aacttaccgt
     4321 agtccataat ttttgcaaca ggcggtttgg cttggggttg aatcaatact aggtcaacat
     4381 tagcgttatc agccaaagct tgcgcttcac tgagtggctt gatgcctagc tgttctccct
     4441 caagaccaat caagcgaact tcacgtacac gaatctcatc attgatgaat aagtcttgct
     4501 ttgctatggt tttcacctct tttgttttat tagagaaaaa caatagcgga ctcgtaaata
     4561 tacaagcccg cacgttatga tagcgtttct tcgaaacttt tcatccgtag ggccaggcaa
     4621 cttaatgtca caaggcgaga agctctcact tctgcttttc tcaactttta tatgatacca
     4681 agttttctag ctcttgtcaa gataaaaagt tattttttga aaagtttgtg tttgtatttt
     4741 ggtttggttt tcgaatcaaa aagagagaac caagttgatt ctctccctat gttagttttt
     4801 ctttagcttc cctataggaa aactaaactt taaaaacttc ctttttacgt gaacttcccc
     4861 atctttcgat aaatagaatc cccactaaca aaaggataat caggcaagga agtaagacca
     4921 tccccatgct ccaatttaga tcgacattat caatctgctt aggtaatctt ccagataaaa
     4981 tctccactga acgcaagtaa gtaaagggaa tcagatgtgc aatcttttga agaggctgaa
     5041 tggtttggat gccaaacaat aagccaacaa tcccaatgag tgaaagaaag aggacaggca
     5101 ttttttgctt gaaaaagtaa gcaatcaaat acacaacttc cacaatgacg ataaaggcta
     5161 agaaagctaa gagcaagcca ggaaataata catcctgcat ctttccaata gttacctctt
     5221 gattcactaa gctataaatc gggtagggat aatctaactg tccaaaacca cttatcagac
     5281 ttcccactag aaaagaaaag ccacagattc cgataaacag cacagttaca tatcccactc
     5341 caactccaag agaggatatt gcaaatgtca cttttgaaac aggatataag tgagctgtgt
     5401 ccagatgatt ttgatatctt tctgcaaata gttgtgttag cataaaaata atcgcaacca
     5461 caaacaagct tgggatgata acctctaaaa tccagacaat ctgatcaatc ccgtgggtcg
     5521 gaaactctaa agtatgtgct tttatgttca agggatacag ggcttggtaa atcttccgtt
     5581 cgcggtcaac ccccattttt aagccagagc tagcagtcgg gtcatttgat acaaattcat
     5641 aattcttctc ttcatcttgc cactgcaaat agtaggcttc tttccagcgc ccttctttta
     5701 gtaaagttag aatttctgtc tttcgcgtca aaagattttt ttgcacgtct aaattatttt
     5761 tagcaaactg gtattcctcc gagctggtat cagacatttg ggagagtttc tcttcatttt
     5821 cattgatagc cctctcgttg gctgcaatgc gactttccaa cctgctctcc aagctgtgtg
     5881 agtttgcagt ctgactattt aaataaaagg taacaccgag tacagataca aataaagcta
     5941 agacaatcca gtttaagcgg cttttgaaaa cttttttcaa taaaaataga ctaacatctt
     6001 tcataaacta aacctcttct atctgcccct gatgaatggt tactactcta tcgcagacat
     6061 caaccaactc ttccttatag tgggaactta aaagaaccag ctgttcttgt ctatcgattt
     6121 gtgctagcct atcaaaaaac ttctgtcgat aatactcatc taagccattt gtaatctcat
     6181 ccatgagcca gcatttggcc tgactgagga aatacatggc aatcaccaag cgttgcttca
     6241 tgcctaagga atacttgcga atgggaagac tgatatagtc agacatttcc caataggcga
     6301 tttcatccct caagttcaga cctgacttcc agatgttttt gataagacga aggtagtcca
     6361 tcccacttaa gtttccatcc agccattcaa tactctcata ataaaataaa gaaggagggg
     6421 ctgcgatatt tccactactt atgggaatta aattgctaat ggcacggaac agggtcgtct
     6481 ttccagagcc attgatagca agaagaccat aaaccctacc ctttttaaag gtgaaatcca
     6541 catcttgcaa gatgacttgt cgcgttttta aggtcacatg agtaagctgc aacatatcta
     6601 gccctccttt ttctcactct ttaagaatta atagcctccg ctgtaatagt ttatgatctc
     6661 ataacgaccg tagttccagc cagaaccaac tggatactca gaatagctgt cataacgaga
     6721 ccatgacgga atccaagcat actgatggtc gtgatagttg gtactatatt cccaaaccgt
     6781 attccaatca tacttgtaac ttttagtgac tgtcacagca gatatactgg actgaaaaag
     6841 accaataatc ataaactaac taattaaacg atttttgcta atttttaatg attttatatc
     6901 ctcaatattg aatacgtttt cattatacca tttttatcat tattatgcaa caaattttta
     6961 gtttatttca ctaatctaca acatttatcc ttcctatcga acactttcga ttttccaact
     7021 atccaacccc ttaaaacgta tagctccttg ctggtcagtt cgataaactt tgctattgat
     7081 accttccagt cgtgtcaatg tttcctgatg ggggagtttc attcgattgc tctttccaac
     7141 tgagataaga gtaagctctg gtttgagttt ttctagaaag gctggacttg atgatttttt
     7201 attgccatgt tggctagctt tcaaaacatt tactttcaag tctggatagt gcttcagcaa
     7261 gtccttctct cctttctcct ccaaatttcc cgtgaagaga aattgcttat ccaagaattt
     7321 cccatacaga actagggtat catcgtgtcc tccatctccc attttccttg gagatagaac
     7381 ttctaactga cttccaaaaa tgggcaagtt ctcccctact gtcatactac gcacctttgt
     7441 ttgagtcgcc tgtagttctg ccacaaattc cttctgtttc agactgtctt ttgatactag
     7501 aatctcccct acatggaaag ccttggtcac ctctgacaaa tctccaacat gctccttgtc
     7561 cgtgttagtc aaaattagct ggtcaatctt agctactcct cgacttttga gatagggaat
     7621 caaggttcgc tgggcattgc tggtcgtcat tttttcttgc catttttcga ttttcttata
     7681 agattctgcc ttaccaccta catctatgag aatggttttc ccagttacat cccgtaggaa
     7741 aatactttct ccttgcccca catccagcat ggtgatttca ttttccagtg gatgcttggt
     7801 caggagaaag agccctgtaa tcaataagca caataccgtt agctttttaa tgttttttct
     7861 caaatcatag accaaagcca aggaaattaa caataggatt aaaaaccatg cattgggttg
     7921 tccaaagacc agaggtctac ttgtcacctg tgacaccaag cgaataatgc cctccaacca
     7981 ttcaaagata aagttcagct gaatgactgg atagagaaag gaaaggacaa ataaaataga
     8041 caagagcggt aagaaggtca agtcaaatag aaaggaaaag acaaaggtca aaaggataga
     8101 caaaggttga aattccgcaa aatagaagga tagaatgggc aatatgccca aggagatgac
     8161 tagactttca ctagtaacag ccttgagccc ctccccttct ttgctggtca tggtcaggat
     8221 aaaagcataa gcgcaggaca agactcctcc tgctgtcaag aaaaagtttg gcatgacaat
     8281 aaagaggaca agcaccgtca aggcaaaatt atccaagccc ttaaccccat gttgagccag
     8341 tagcttttgc aagagactgc gaataaccga tgctgaaaat ccagttagtc ccgcatagat
     8401 aagggaaaag ggataagtca gccatttcaa cttttcttgg gtcaagccca atcgcaagag
     8461 aagtttctta aatccattca tgaaaaaacc tacctgcata ccagataggg caaagaggtg
     8521 gataattcct agactggaat aaagctcatt catctcctca aagtcggtgt ccagatgtcc
     8581 cagcaagagt cctgtcatgt aattgcgcat agggtctgga aagtgcgtct taatccaaac
     8641 cacagccttt cgacgtaaac tggacaagtt ttctcctata tcccaactgc caatcttttg
     8701 aagtgactgg attgttttga tattgagagt ctggtaaatt ccctgagtct tcagataggc
     8761 ttggtaatta aagccaccaa aatttctctg cccttctggc tccgaaagct tcccttctag
     8821 tcctatctca tgcaggtcgg ttaaagcttg aaaggcttct ttctcctcct cggactggag
     8881 tttataatag acttggaaag cacgaccgtt agacttgcca cgaaaggata gactatcacc
     8941 attaacctta atagtatcag gcaaaatccg taccctttca acagaatccg ccagattttg
     9001 actcgcttga ctctgttgcc aattttgaaa aacaaaccaa aatccaaaga ttccgcaaat
     9061 tattagaact ttaccagcag atttccacgg aaattggata aagagacaga ctagcagaaa
     9121 aacaaagccc aacaaagcaa gataagatgc tgagaaaata gcgtaataaa gccaaagtaa
     9181 tagaaaactc aggtaaatta ggggaataga gaaattctta atccactgta acatagtctt
     9241 taagcttttc tattgttttg ccaccaatgc cagagacctt cttgagctcg tctactgact
     9301 tgaacttgcc atttgcctca cgatggtcga taatgtcctg agctcgtttt cctcccagtc
     9361 ccttgacctg cttgagttct tccagactgg ccttgttgag attgaccttc ttttccttgc
     9421 ttattgaaga agctgtcccc gaaccagtct gttgactaac tgcttcttct cccttagtag
     9481 gaacgtaaac cagagcctca tcactaactt tctgagctag attgagcgac ttgctgtctg
     9541 cttgctctgt caagccacca gccttctgaa cagcatcatt gactcgacta cctacaggca
     9601 agtcataaat ccctggcgat ttgacagcac ctttgacatc tactgtgatt agatcttgtt
     9661 caaggggttc ttccttctct tccttgttca cttccttttc ggataccaaa tccttggaaa
     9721 cagctgcaac ttcagcctgc aaattcgttt cctttacagg tgtttgtgga gctggcttta
     9781 gcaggaaaaa tccgcctaca agcaagccca gaccagtaca gatgacgatg attttatact
     9841 ctttgatttt ctcgataatt gcttccatat tttctcctct cttagattat tcgtaagagg
     9901 aagaaaaaac agtcgaaaaa tttcttttca actgcttatt tatttgcaaa atagtcttcc
     9961 ttggtcaaga cataatgaac tcttgtcacg attcggcctt tttcatgctg gtccatacaa
    10021 gcatatggtt ctgcatggga aaaacgcatg cctgatttct ccatgacctt tcctgacgca
    10081 gaattgtcct tatcgtataa agcaactaac ttattcattc ctatcttctc aaaagctagc
    10141 tcaatcacag cacgattggt ttctggcgtt aatccttgat tccaatactt tttattgata
    10201 atgtagccaa tagctgcctt cttaagaaca ggatcaatct tgtgtaagtc aatagttccg
    10261 ataaacttgc cgttatcttt taattcaatc ccccaacgtc ccaagggatt agccaagtag
    10321 aactgagcaa tgttattctt ggtttcttcc aagctttgat tggttggaaa agtgtaacgt
    10381 gtattaccct tgtccgaggc atagtcaaac attgcttccg catcatccaa agttacaggt
    10441 ctaagcaata aacgctccgt ttctatagac ggatactggg caaatttcac aaatattgat
    10501 tccatacttt tccctccatt agagcttgat tttcactagt ctagcataaa aaaatttgga
    10561 tgacaagttt ttcttgattt ttgaagcggt ttcatataca atgaaaccgt cacatttttg
    10621 atttatgaac tggaatgtga caaccaaaac aagaccgtca attgaaaggt aggttatctc
    10681 aatgttaatc ggaatcccaa aagaaattaa aaataacgaa aaccgtgtcg ccctcacacc
    10741 tgcaggtgtt catagcttag ttagtcgtgg tcatcgtgtc cttatcgaaa caaatgctgg
    10801 tctcggttct ggctttactg atgctgacta tcaaaagcaa ggagctgaga ttgtcgctac
    10861 tgctggtgaa gcttgggcag cagagttggt tgtgaaagta aaagaacctt taagttctga
    10921 atacggttac ttgcgcgacg atcttcttct cttcacctac ttgcacatgg ccgctgctcc
    10981 agaattagca gatgctatgt tagcagcaaa aacaacagga attgcctatg aaactgttcg
    11041 tgacaatcaa ggacaactac cgctcctcgt tcctatgagt gaggttgcag gtcgtatggc
    11101 tgtttaaatc ggagctcact tccttactaa gcaagctggt ggctctggtg ttctacctag
    11161 tggtgtacca ggtgttccaa aaggaaaagt aactatcatc ggtgatggtg tcgtcggtac
    11221 acatgctgcc cgcatcgccc ttggtcttgg tgctcaagtg actattttag atattagtgc
    11281 caagcgtctc tcagttctag aagaagtctt tggaagtcaa attcaaactc ttatatctaa
    11341 ttcattcaac attgaagcaa gtatgagaga tgctgatgtg gtgattggag ccattctcat
    11401 ccctggtgca aaagcaccgg aattggtgac agatgagatg gtcaaacaaa tgcgtccagg
    11461 ctctgtatcg ttgacgttgc tgttgaccaa ggtggcgtta tcgaaacagc tgaccgtgtg
    11521 acaacgcacg atgaacccgt ctatgaaaaa cacggtgttc tccactatgc cgttgccaat
    11581 atccctggtg cggttgcccg cacttcaacc atcgccctaa ccaatgtcac tcttccttat
    11641 atcgaagctt tggctggcaa aggattcgca caagcaatct ctgaagatga aggcttgcgt
    11701 caaggtgtga ccacttatca aggttacttg actagcctac cagttgctca aggacttaat
    11761 cgtgactaca ctgatatcaa tgatttagta taaattttga aaagaaaagg gtgacttcgc
    11821 aagtcctacc cactgtgctt tgtgtcatca gctattacat cgttggttta ttgtactgta
    11881 tactttgcaa ctggagactt tcgttccaga ctcaattgtg cataagaaac tctaaattga
    11941 ataaagtcaa cagagtttcg cccaaccact tcgtcttgta atgacaatta tataaaccaa
    12001 aggaagctga gctctttagt cccagcttct ttttatatat aaaattttac ccgtgcaaag
    12061 acagggcctt agcagacttc ttttttactt cgttcaccct tgctttttct ttttaggttt
    12121 gggcgttggc agttggttat acatagctaa aatcaggtct tatagaaaca tcttattatc
    12181 aagttcttcc actcaaatca tttctttggc acctttgtat ggaaactcaa aagaagattg
    12241 gtcaatctta tctaagactg cttgcacggg tttaactaaa aagcgatcgt cataaatgcc
    12301 gccaataatc ttgccgcgga agtaaagaat atactccccc atcatggaac ggtaagtcac
    12361 atcatctaat cctgataatt gttccaaaac aaattccaaa tagttcttac ttgatgccat
    12421 ttctaatctt ctaggctctg ttcagcgata acaaccgtat agagttcttg cttaacctcg
    12481 catccaattg atttaaagcc ctgcttttcc caaaaatgct gagattgcgg atttccctta
    12541 acataagcca aacgtgcctt tcgaaagttc ttagcaaaat aagctagtgc ttctgtcaca
    12601 atatgactac caatcccttt cctctgatag gcttgatcaa ccataaacaa accaataaaa
    12661 acagtctcct catcaggatg tgcatagaca aaatctataa cagccacaag gtcagatcca
    12721 ttccaaaatc caacaaaaaa cttatcagcc ttagctttac cttcaggtag acaaagcatg
    12781 tcctctttta cagttgcaaa atttggctct ggtggacaat gctgaaaata cagaggatta
    12841 ctttcatata aagataaaat acttggaata tccttttcag ttagtatcct acaactgtaa
    12901 tacttagata gttggtcaat catcttttca aattcctact ttcttgtgca ctgtgattat
    12961 gacacaggaa gatgcactga tcgtcatcag ccacataaaa gttctttcca tcgtgcctaa
    13021 tcgttgtctc aaacctttgg ataaaacctt tagcctatac aactggattt tcctctctca
    13081 aaagtatatt cttttgcagg caaacttcct caaaatcagt cgtgtgcaac ttcagtagaa
    13141 tattcatagg ctcggataat ctgagcgaca actggatggc gaaccacatc cttggctgaa
    13201 aaatgaacaa agtcaatctg atggatgttc ttgagtttct cttgagcatc aatcaaaccg
    13261 gacttgacat tacgtggcag gtcaatctga ctaatatctc cattgacaat catcttagaa
    13321 tgaaaaccta aacgagtcaa gaacatcttc atctgcatga tggtcgtatt ttgcgcctca
    13381 tcgagaatga caaaggcatc atccaaggtc cgtccacgca tataggcaag gggcgcaatc
    13441 tcgataattt cacgctccat gagtcgagtt gtttggtctt tccccagaat ctgatacaag
    13501 gcatcgtaaa caggacgaag gtaaggatcc accttctcct taagatcacc cggaagaaat
    13561 ccaagactct ctcccgcttc caccgctgga cgagttagga taattcgctt gacttgccca
    13621 cgtttaaggg cagtcactgc caaggtcact gcaaggaagg tcttccctgt acctgctggc
    13681 ccaattccaa aggtcacatc atgctgtttg acactgtcca cataaagctt ttgccctagg
    13741 gttttgacac ggataggttt cccagtatta tctttgataa tttcttcttc gtaaagggcg
    13801 acaaacttgt caatttcatc atttttgacc atgctaatcg cagtgactac atctggcgta
    13861 ccaacggtca tcccacgatt taccaagacc atcaaagcct gaataacttg acgggcttcc
    13921 tcacaggcag actcttctcc caaaacctgg acaatctccg tacgagcatg aatcacaaca
    13981 tcaagctctt cttccatcaa acgaagatgg cgttcattgg aaccaaaaag atgaaacagg
    14041 tcatctggat gactcagttg aatgtctatt gaatgttcct tcaaataaag aacctctcta
    14101 atccttttat ttctttttat tatagcagag ggatggagaa attactagcc caaacccaat
    14161 gaataaatgc tagtgttcta gatattcctg ccaaatgctg tcaaaatctc ctaggttaaa
    14221 agagaaactg gcatgctcct ccaaaaagcg actgacctca tcaaaatcat ctgtatgttt
    14281 tggaaaagct gcctcttcaa aagcgaggtc tgccaaaatt gctttgggac tgttactttt
    14341 aggattgcgc tcggtcatga gccaagtgta aaatgatttt ctcataagcc tccctaaatc
    14401 aactctgtcc caaactggtc ctgcttgatt ttaccagcct tcataagacc acctaaagct
    14461 ttcttgaact gacctttaga aatgccaaag gttgccttga tgtcgtctgg agatgactta
    14521 tcatttaagg tcatgaaacc gccattactt tccaaataag tcaaaatcat ctgagcatcg
    14581 ttttccaaca tttcaaagga gcgtggtttg agggagaggt tcagagtgcg gtccacttca
    14641 cggaaaccaa taacgcgcgc atctaatact tgccccaaac gtggctctgc gtaacgctcg
    14701 ctaggatgaa taaaaccaag catattattt tctggtaggt aaacaaaagt tcctgacagc
    14761 ttgagacggt aaacaatggc tggccagttt tggttctgca tgttgttgta ggcaggacga
    14821 gcaagacgtt ggaagtcttc ttgataagcc aagaggcccc agatacggtc tttcttatcc
    14881 acttcaagac ggatgtagag ttggtcgccc ttcttaggcc agagttcctt gagctcaggg
    14941 agaatatcga gtgacacaac gatttccttg tcaggaaggc ctgtatccac aaagacaccc
    15001 aaatccttac gaacctctgt gacacgtccc caaccaaatt ggtcctgagt ggcagtcact
    15061 tctaaggttg tcaggcggag tttttgcttc atatccgtgt atgcaaaacc tttgaccgta
    15121 tcccctactg tatgttgacc ttcttcctta gcaagagcat aggtttgacc atccttttgc
    15181 acaaagtaaa aacggtcatt ttcatcgatg atcagtccaa cgataaaact tgcaagattt
    15241 gtattcatat ttccttcttt cgaataaaac tcagccagca atgccaactg agtttttctg
    15301 tttattttta gacttccaaa agttctttct ctttgttagc agtcatgtcg tcgatgtgtt
    15361 taacagcatc gtctgttact ttttgaatat ctttttcaag agtcttcaat tcgtcttcag
    15421 tgatttcttt tgctttttct tgtttcttag cttcgtccat agcatcgcga cggatattgc
    15481 ggacagccac tttagcattt tcgccgacct tcttcacttc tttagcaagg tcacgacgag
    15541 tttcttctgt aagagctggg ataaccaagc gaatcacaga accgtcatta gccggtgtga
    15601 taccaagatc agaagcgttc aaggcacgtt cgatgtcttt caatgaagac ttgtcaaatg
    15661 gtgttaccaa caaaacacgc gcttctggaa tcgtaattga agcgatttgg ttaagaggag
    15721 tttcgactcc atagtattct acatgtacac ggtcaagcaa gcttgcattg gcacgaccag
    15781 cacggatacc accaaattca cgagcaagtg attggtgaga ttgggtcatt ctctctttag
    15841 ctttttcaat aattacgtta gccatattct ttcttattcc ttttcttcga tattatttga
    15901 aactgttgtt ccgatatttt caccaaatac gacacgtttg atgttgcctg attggttcat
    15961 gttgaagaca accaagtcaa tgtcgttgtc cattgagagg gttgaggctg ttgagtccat
    16021 gatacgaaga cctttgttga taacatcacg gtgggtcaat tcttcaaact taacggctgt
    16081 cttgtccttc ttaggatcgg cattgtacac accatcgacg ccatttttag ccatgaggat
    16141 ggcatctgct tcgatttcag ctgcacgaag ggccgctgtt gtatctgtcg agaagtatgg
    16201 tgaaccaatt ccagcaccaa agataacgat acggcctttt tcaaggtgac gaagggcacg
    16261 tccacggaca taaggctctg ccacttgttg catagcaata gctgtttgta cacgcgtatc
    16321 aaccccaact tgttgcaatg aatctgccat cacaagagca ttcataacag tcccaagcat
    16381 tccagtgtaa tctgcctgaa cacggtccat acctgcttct gctgcaggtt ctccacgcca
    16441 aagatttcct ccaccaataa caagggcaat ttcgatacct aagctatgaa cttcttgaat
    16501 ctcttttgcg attgtttgaa ctgtttggat atcaatccct acgccacgtt caccggcaag
    16561 ggcttcacct gataacttga ttaaaatacg tttatacttg ggattcgcca ttttcactct
    16621 ccttctttca tcctacctat tttatcacaa tttctaagat ttttatagta tcatgagcaa
    16681 ttctttcaaa aaaattagac agtcaaaaat tcctctaagt cggcaagggc acgctctgca
    16741 attttttcat aacgagcctt cttatcacgg atacgctcgc cttccaactc cttgatgatc
    16801 ccaaaattga cattcattgg ttggaaatgt ttgctgtcgg catgggtaat gtaatgagct
    16861 aagcttccaa tcgctgtcgt ctcggggaaa ataacctcgc tttcttcctt gaagagacga
    16921 gctgcgttaa ttcccgcaac taagcccgaa gccgccgact caacatagcc ttccaccccc
    16981 gtcatctgac cagcaaagaa gagatttggt tgtttcttgg aacggtaagt ctgctcaaga
    17041 agatttggtg aatccatgta agaattgcga tgcatgacac cataacggac aaactccgca
    17101 ttttcaagac ccggaatcat ttggaagaca cgcttttgtt ctccccattt gaggtgggtc
    17161 tggaaaccaa caatattgta taggctacca gctgcattat cctgacggag ctggacaacc
    17221 gcataaggtg ttttaaattc tccatcacga ggtcctgtgt agtcgtccgg atactcaaga
    17281 ccaactggtt tcataggacc ataaagcatg gttttaatgc cacgtttggc catgacttcg
    17341 ataggcatac atccttcaaa gtacttttct ttttcaaaag aattaagcgg tgcttcttct
    17401 gcattgacca aagcttcatg gaaatccata aattcttgct tggtcatagg ggcattgagg
    17461 taggccgctt ctcccttatc ataacgtgat ttgaggtaga ccttgctcat atcgatagtg
    17521 ttgacatcga taataggcgc tgccgcatcg tagaaataaa aaccatcacc gtcattaagg
    17581 gcatgaatct tttcagccaa ggcatcactt gtcaaaggac cagtagcgat aaccgtaata
    17641 acatctgtcg gcaattctgt aatttcatca cgaaccactt caatcaaggg gtggttggca
    17701 actttttcgg tcaccatttg agagaaacca tcacggtcca ctgcaagggc accacctgca
    17761 ggaacacgtg tagcctcagc agattccaaa atcacagaac ccaagcgacg catttcttcc
    17821 ttaaggaggc caacagcatt tgtcaaagca tctccacgca aggaattgga acaaaccaac
    17881 tcagcaaaat tgtctgtttt gtgctgaggt gttgacttga caccacgcat ttcataaagt
    17941 ttaactggaa taccacgctc tgcgatttgg taggctgctt cagaacctgc caaaccagca
    18001 ccgataacat tgatataaga ttgagacacg acactaatac ctctttggga gtatgaagtt
    18061 aagattcaca ttgaaaaagc caatcagact tacgagcttt cgagtttctt ggctcaggct
    18121 gaaaaagtcc acaggacttt ttcactccca caaatctttc tatttttttc ttctactagt
    18181 ataacaaaaa aagggaagaa ggcaaacttc cctgtttagt cattttcttg atgtaaagag
    18241 ataaagagta ttccagttaa gaatcaatta tatgctactc tataaaatct tttccacata
    18301 acggatcgat agggactgtt attctatctc ttgctataac cgtattatct aaaacagcat
    18361 aacattcaac atagtgatct cctttaaact gtgaatcttc gtgatatttt attttacctg
    18421 aaaaaatagc accacgctca caatttcttc taatagcctc agcttcaata tttcttactt
    18481 tccaatagac ttcctgcgaa acaaaatatg gtatagtagt tctatgaatg atgaagcaag
    18541 taaacaacta actgatgcac gatttaagcg tcttgttggt gttcagcgca cgacttttga
    18601 agagatatta gctgtattaa aaacagctta tcaacttaaa cacgcaaaag gtggacgaaa
    18661 acctaaatta agcctaga
//
LOCUS       DBEJJV010000040        18216 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.040, whole genome shotgun sequence.
ACCESSION   DBEJJV010000040 DBEJJV010000000
VERSION     DBEJJV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18216
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.040"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            88..1026
                     /gene="msrB"
                     /locus_tag="ACL3GT_001656"
     CDS             88..1026
                     /gene="msrB"
                     /locus_tag="ACL3GT_001656"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HGR0517297.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1084..2808
                     /locus_tag="ACL3GT_001657"
     CDS             1084..2808
                     /locus_tag="ACL3GT_001657"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0517298.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPIDKGSIDL
                     YRDGSSPRNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2810..4558
                     /locus_tag="ACL3GT_001658"
     CDS             2810..4558
                     /locus_tag="ACL3GT_001658"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0517299.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDTFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4905..6164
                     /locus_tag="ACL3GT_001659"
     CDS             4905..6164
                     /locus_tag="ACL3GT_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HGR0517300.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6240..6375
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6414..6914
                     /gene="rplJ"
                     /locus_tag="ACL3GT_001660"
     CDS             6414..6914
                     /gene="rplJ"
                     /locus_tag="ACL3GT_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HGR0517301.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6990..7358
                     /gene="rplL"
                     /locus_tag="ACL3GT_001661"
     CDS             6990..7358
                     /gene="rplL"
                     /locus_tag="ACL3GT_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HGR0517302.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7545..7715
                     /locus_tag="ACL3GT_001662"
     CDS             7545..7715
                     /locus_tag="ACL3GT_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517303.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            7715..7963
                     /locus_tag="ACL3GT_001663"
                     /pseudo
     CDS             7715..7963
                     /locus_tag="ACL3GT_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            7977..8317
                     /locus_tag="ACL3GT_001664"
                     /pseudo
     CDS             7977..8317
                     /locus_tag="ACL3GT_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134542.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8310..8690
                     /locus_tag="ACL3GT_001665"
     CDS             8310..8690
                     /locus_tag="ACL3GT_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HGR0517304.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            8703..8936
                     /locus_tag="ACL3GT_001666"
                     /pseudo
     CDS             8703..8936
                     /locus_tag="ACL3GT_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            8939..9526
                     /locus_tag="ACL3GT_001667"
     CDS             8939..9526
                     /locus_tag="ACL3GT_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0517305.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
     gene            9728..9865
                     /locus_tag="ACL3GT_001668"
     CDS             9728..9865
                     /locus_tag="ACL3GT_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR0517306.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            10044..12653
                     /locus_tag="ACL3GT_001669"
     CDS             10044..12653
                     /locus_tag="ACL3GT_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="HGR0517307.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKSMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            12686..14626
                     /locus_tag="ACL3GT_001670"
     CDS             12686..14626
                     /locus_tag="ACL3GT_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HGR0517308.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGISSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRAPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAADHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            14623..16230
                     /locus_tag="ACL3GT_001671"
     CDS             14623..16230
                     /locus_tag="ACL3GT_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0517309.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            16245..16985
                     /locus_tag="ACL3GT_001672"
     CDS             16245..16985
                     /locus_tag="ACL3GT_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0517310.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            16988..>18216
                     /locus_tag="ACL3GT_001673"
     CDS             16988..>18216
                     /locus_tag="ACL3GT_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517311.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILP"
BASE COUNT         5825 a         2880 c         3700 g         5811 t
ORIGIN      
        1 aacatatata cggtaaggtg acgctaacgt ggtttgaaga gattttcgaa gagtattagt
       61 taaaaacgtg ataaaggaga aataaagatg gcagaaattt atctagcagg tggttgtttt
      121 tggggcctag aggaatattt ttcacgcatt tctggagtgc tagaaaccag tgttggctac
      181 gctaatggtc aagtcgaaac gaccaattac cagttgatca aggaaacaga ccatgcagaa
      241 acggtccaag tgatttacga tgagaaggaa gtgtcactca gagagatttt actttattat
      301 ttccgagtta tcgatcctct atctatcaat caacaaggga atgaccgtgg ccgccaatat
      361 cgaactggga tttattatca ggatgaagca gatttgccag ctatctacac agtggtgcag
      421 gagcaggaac gcatgctggg tcgaaagatt gcagtagaag tggagcaatt acgccactac
      481 attctggctg aagactacca ccaagactat ctcaggaaga atccttcagg ttactgtcat
      541 atcgatgtga ccgatgctga taagccattg attgatgcag caaactatga aaagcctagt
      601 caagaggtgt tgaaggccag tctatctgaa gagtcttatc gtgtcacaca agaagctgct
      661 acagaggctc catttaccaa tgcctatgac caaacctttg aagaggggat ttatgtagat
      721 attacgacag gtgagccact cttttttgcc aaggataagt ttgcttcagg ttgtggttgg
      781 ccaagtttta gccgtccgat ttccaaagag ttgattcatt attacaagga tctgagccat
      841 ggaatggagc gaattgaagt tcgttctcgt tcaggcagtg ctcacttggg tcatgttttc
      901 acagatggac cgcgggagtt aggcggcctc cgttactgta tcaattctgc ttctttacgc
      961 tttgtggcca aggatgagat ggaaaaagca ggatatggct atctattgcc ttacttaaac
     1021 aaataaaaca gagagtgggg cttcccactt tcttcatttc tagaatatga atagaaggga
     1081 tttatgaaac acctattatc ttacttcaaa ccctacatca aggaatcaat tttagccccc
     1141 ttgttcaagc tgttagaagc tgtttttgag ctcttggttc ccatggtgat tgctgggatt
     1201 gttgaccaat ctttacctca gggagatcaa ggtcatctct ggatgcagat tggcctgctc
     1261 cttatctttg cagtaattgg cgttttagtg gccttgatag ctcaatttta ctcagcaaag
     1321 gcagcagtag gttttgctaa ggaattgaca aacgatcttt atcgtcatat tctttccttg
     1381 ccaaaggaca gcagagaccg tctgacaact tctagtttgg ttactcgctt gacttcggat
     1441 acctaccaga ttcagactgg tatcaatcaa ttcctgcgtc tctttttacg agcgcccatt
     1501 atcgtttttg gtgccatttt tatggcttat cgaatctcag ctgagttgac tttctggttc
     1561 ttagtcatgg ttgccatttt gaccattgtc attgtagggt tatctcgatt ggtcaatcct
     1621 ctctacagta gtctcagaaa gaaaacggac caactggttc aggaaacgcg ccagcaattg
     1681 caagggatgc gggttattcg tgcttttggt caagaaaaac gagagttaca gatttttcaa
     1741 acccttaacc aagtttatgc tagattacaa gaaaagacag gtttctggtc tagtttatta
     1801 acacctctga cctatctgat tgtcaatgga actcttctcg ttattatctg gcaaggctat
     1861 atttcaattc aaggaggagt gctcagtcaa ggtgctctca ttgctcttat caattacctc
     1921 ttacagattt tggtggaatt ggtcaagcta gccatgttga taaattctct caaccagtcc
     1981 tatatctcag ccaagcgaat cgaggaggtc tttgcggaat ctcccgaaaa catccattca
     2041 gaattagaac aaaagcaagt taccagtggt cgggttttac aagtccaaga attgactttt
     2101 acctatcctg atgcggccca gccttctctg agatacattt cctttgatat gactcaagga
     2161 caaattctag gtatcatcgg gggaacgggt tctggtaagt caagcttggt gcaactctta
     2221 cttggacttt atccaataga taaggggagc attgaccttt atcgagatgg atctagtcct
     2281 cgtaatttag agcagtggcg gtcttggatt gcttatgttc cccaaaaggt cgaacttttt
     2341 aagggaacta ttcgttccaa cttgacttta ggtttaaatc aagaagtgac tgatcaagaa
     2401 ctctggcaag ccttggaaat tgctcaagct aaggattttg tcagtgataa ggaaggactc
     2461 ttggatgctc tagttgaagc aggagggcga aatttctcag gtggacaaaa acaaaggctg
     2521 tctatcgcac gagcagtctt gcgccaggct ccgtttctca tcctagatga tgcgacctca
     2581 gcactggaca ccattaccga gtccaagctc ttgaaagcta ttagagaaaa ttttccaaac
     2641 atgagcttaa ttttgatctc tcaacgaacc tcgactttac agatggctga ccagattctc
     2701 ctcttggaaa aaggtgagtt gctagctgtt ggcaagcacg atgacttgat gaaatccagt
     2761 caagtctatc gtgaaatcaa tgcatcccaa catggaaagg aggactagaa tgaaacgaca
     2821 aactgtaaac cagacgctca aacgtttagc cgtagattta gcaaaccatc ccttcctcct
     2881 tttcctagcc tttctaggaa ctattgccca agttggctta tcaatttatc tacctattct
     2941 gattgggcag gtcattgacc aagtcctagt ggctggttca tcaccagttt tttggcagat
     3001 ttttctccag atgctcttgg tggtaatagg aaatactcta gtacaatggg ccaatcctct
     3061 cctctataat cgtctaatct tctcttatac cagagattta cgagagcgaa tcatccataa
     3121 actccatcgg ttaccgattg cttttgcgga tcggcaaggc aatggagaga tggtcagtcg
     3181 tgtaaccacg gacatcgaac agttggcagc tggcttgacc atgattttta accaattttt
     3241 cattggtgtt ttgatgattt tggttagtat tctagccatg ctccaaattc atctcctcat
     3301 gactctctta gtcttgctgt tgacgccact gtccatggtg atttcacgct ttattgccaa
     3361 gagatcctat catctcttcc agaagcaaac agagacgagg ggaattcaga ctcagttgat
     3421 tgaagaatcg cttagccagc agactataat ccagtccttc aatgctcaaa cagaatttat
     3481 ccaaagattg cgtgaggctc atgacaacta ctcaggctat tctcagtcag ccatctttta
     3541 ttcttcaacg gtcaatcctt cgactcgctt tgtaaatgca ctcatttatg cccttttagc
     3601 tggagtagga gcttatcgta tcatgatggg ttcagccttg accgtcggtc gtttagtgac
     3661 ttttttgaac tatgttcagc aatacaccaa gccctttaac gatatttctt cagtgctagc
     3721 tgagttgcaa agtgctctgg cttgcgtaga gcgtatctat ggagtcttag atagccctga
     3781 agtggctgaa acaggtaagg aagtcttgac cagtgaccaa gttaagggag ctatttcctt
     3841 taaacatgtc tcttttggct accatcctga aaaaattttg attaaggact tgtctatcga
     3901 tattccagct ggtagtaaga tagccatcgt tggtccgaca ggtgctggaa aatcaactct
     3961 tatcaatctc cttatgcgtt tttatcccat tagctcggga gatatcttgc tggatgggca
     4021 atccatttat gattatacac gagcatcatt gagacagcag tttggtatgg tgcttcaaga
     4081 aacctggctc acacaaggga ccattcatga taatattgcc tttggcaatc ctgaagccag
     4141 tcgagagcaa gtaattgctg ctgccaaagc agctaatgca gactttttca ttcaacagtt
     4201 gccacaggga tacgatacca agttggaaaa tgctggagaa tctctctctg tcggccaagc
     4261 tcagctcttg accatagccc gagtctttct ggctattcca aagattctta tcttagacga
     4321 ggcaacttct tccattgata cacggacaga agtgctggta caggatacct ttgcaaaact
     4381 catgaagggc cgcacaagct tcatcattgc tcaccgtttg tcaaccattc aggatgcgga
     4441 tttaattctt gtcttagtag atggtgatat tgttgaatat ggtaaccatc aagaactcat
     4501 ggatagaaag ggtaagtatt accaaatgca aaaagctgcg gcttttagtt ctgaataagc
     4561 cattctcttt tgaaagttta tggacgaaaa aagttgcctt cgagtgactt ttttgttaca
     4621 atagctagaa aaattgttca ctgtaatact caatgaaaat caaagagcaa actaggaagc
     4681 tagccgtagg ttgctcaaag cacagctttg aggttgtaga taagactgac gaagtcagtt
     4741 caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagctcaaaa cactgttttg
     4801 aggttgcaga tagaactgac gaagtcagta accacaccta cggcaaagtg aatctgaagt
     4861 ggtttgaaga gagtacaact tgtcttttaa aaaaggagtc tataatgaaa gtctttcagc
     4921 atgtaaatat cgtgacttgt gatcaaaatt tccatgttta tcttgatgga atcttagcag
     4981 tcaaggattc tcaaatcgtc tatgtcggtc aagataagcc agcgttttta gaacaagctg
     5041 agcagattat agactatcag ggagcttgga ttatgcctgg tttggtcaat tgtcacaccc
     5101 attctgcaat gacaggtctg agagggatcc gagatgacag caatctccat gaatggctca
     5161 atgactatat ctggccagca gaatctgagt ttactcccga catgactacc aatgcggtca
     5221 aagaagccct gacagagatg ctccagtcag gaacaacaac ctttaacgat atgtataatc
     5281 ccaatggtgt ggatatccag caaatttatc aggtggtgaa aacttccaag atgcgttgtt
     5341 atttttctcc gactctcttt tcttcagaga cagaaacaac tgctgagact ataagcagaa
     5401 ctcgatccat catagacgaa atcttaaaat ataaaaatcc aaatttcaag gttatggtag
     5461 cacctcattc tccgtatagc tgcagtagag acttgctgga agcgagtttg gaaatggcaa
     5521 aagagctaaa tattccgctc catgtccatg tggcggagac caaggaggag tcaggaatta
     5581 tcctcaaacg atacggcaaa cgcccccttg cttttcttga agaactgggt tatttagatc
     5641 atccgtccgt atttgctcac ggggtcgaat taaacgagag agaaattgaa cgcttggcat
     5701 cttctcaagt ggctatcgcc cacaatccta tcagtaacct caaactggca tcaggaattg
     5761 ctccaattat ccagctccaa aaagcgggag tagcagtcgg aattgcgact gactcggttg
     5821 cttccaataa caatctagat atgtttgagg aaggaaggac tgcagctctt cttcagaaga
     5881 tgaaaagtgg ggatgccagc cagtttccaa tcgaaacagc tctcaaggta ctgacaatcg
     5941 aaggggctaa ggtccttgga atggaaaatc agataggaag tctggaagtc ggcaagcaag
     6001 cagattttct ggtcattcaa ccacaaggga aaattcatct ccaacctcag gaaaatatgc
     6061 tgtctcacct ggtttatgca gttaaatcta gtgatgtaga tgatgtttat atcgccggag
     6121 aacaggttgt taagcaaggt caagtcctga cagtagaact ttaaaagaaa aatcacgaaa
     6181 aattttaaaa aaagtttgca aaaatcttgc attctttttt tgactatgct atacttatat
     6241 acggtttaaa aaaactgcct aagacagtag gggagatcga ctcataaata tcctaccgag
     6301 gacaaaacgt atcatgtaaa aagaagcgta ttgtactttc gtgtctaggt ttgggcgcgt
     6361 ttttcttttt gaaaaattcc ccaagcaaaa taattacgga ggtgaacaca ctaatgagtg
     6421 aagcaattat tgctaaaaaa gcggaactag ttgacgtagt agctgaaaaa atgaaagctg
     6481 ctgcatctat cgtcgttgta gacgctcgtg gtttgacagt tgagcaagat acagttcttc
     6541 gtcgtgagct tcgtggaagc gaagttgagt ataaagttat taaaaactca atcttgcgtc
     6601 gtgcagctga aaaagctggt cttgaagatc ttgcatctgt atttgttgga ccatctgcag
     6661 tagcattttc taatgaagat gttatcgcac cagcgaaaat cttgaacgac ttttctaaaa
     6721 acgctgaagc acttgaaatt aaaggtggtg caatcgaagg cgctgtcgca tctaaagaag
     6781 agattcttgc acttgcaact cttccaaacc gcgaaggact tctttctatg ctcctttctg
     6841 tacttcaagc gccagtgcgc aacgttgctc ttgcagtcaa agcggttgca gaaagcaaag
     6901 aagacgcggc ttaatcttaa gctacatagc gtagcctagc tacgaaaaaa actattataa
     6961 aatttaaaac ttatttggag gaaataacaa tggcattgaa cattgaaaac attattgctg
     7021 aaattaaaga agcttcaatc cttgaattga acgaccttgt aaaagctatc gaagaagaat
     7081 ttggtgtaac tgcagctgct cctgtagctg ttgctgcagc tgatgcagct gatgctggtg
     7141 ctgctaaaga ttcattcgac gttgaattga catctgcagg cgacaaaaaa gttggcgtta
     7201 tcaaagttgt acgtgaaatc actggtcttg gtcttaaaga agctaaagaa cttgttgacg
     7261 gtgcaccagc acttgttaaa gaaggcgttg caactgcaga agctgaagaa atcaaagcta
     7321 aattggaaga agctggagct tcagttactc ttaaataata gagtatcgca atttgattgc
     7381 ggaatcccta tttaccagtc tttgagagcg ataagcgatt gatagaaact gataaattga
     7441 tttggtttcc tgccaaaaat tctttggcag gatttttgtt ttaataaact ttcgggggta
     7501 gacactagat tgtctacccc tttttttgtg tttcggaggt aattatgcaa aaggaaggac
     7561 agtcatcacg tcaattcgtg aagagtcatc tcatgactat catgggagtt gatattgtaa
     7621 aagcaactca gttagttgat gaaatggaac aagtaggttt aatccgattt gatgaatttg
     7681 gaaatgttgg aattttagtc ttggagggac aataatgaag cgtattaccg ctaatcaata
     7741 tcagacatca gagcgttatt ataagctccc caaactttta tttgagagtg aacggtataa
     7801 gaatatgaaa ctggaggtta aggtggttta ctcagtttta aaagatcggt tggagttgtc
     7861 tttgagcaaa ggttggattg atgaggatgg ggctatttat ttgatttatt ccaattcaaa
     7921 tttgatggca cttttaggct gttcaaagtc aaaattactc tccatgtgag tttgaagtga
     7981 catttttaga tgattaccat aaaaaacata actacccact attttacgaa tcctatcttc
     8041 aaaacgttat ggaattcctt gaaagtcaag acataaagaa tggggttgat gcctttgtag
     8101 atgatcatca aaatctcgtt tttgttttat atggacaagg ctatcgagcc gagggaaaag
     8161 agggaatact tacaacccaa gtaactgtaa aagcttatga tgaagacaag aaaccgatta
     8221 acttcgcaaa tttattagat tccttaattt attagattcc ttaatcgtgt cagaatatca
     8281 aatggaaccg aatctttggg aggtctccca tgattgatct ctatctaagt aaaaatagac
     8341 aaagaaatca acttctttta gatttcttcc aaaactatgg catagaggta tcttgtcatt
     8401 cagtttctga aatgacaaag gacaaattaa ttgagatgat gagctattct tcagattgtt
     8461 ttgagttttt atctcccaat ttattacgat ttaagaaccg tgacaatcta agattaacgg
     8521 atttcgttga gataatttta aaaaatcctg aactaaccat cagacttcct cttgcggttt
     8581 caaataagcg agtttatcca agtctgaatt tggaagaggc tagagctcta ttgccaagag
     8641 atacgaaaca attgatttac atggcgcaaa cacattattt atctaactaa aggagaagca
     8701 atatggctga acgattttgg gagaacttgt ccattatttt ggctgaaaga aatatcagct
     8761 ggattgagtt aaccagaaaa atgtttgcgg gagagtttca ctatccaagt gaattgaatc
     8821 gtttgtatca aaagattcgc cactagaaga tggaacaatg aatgcctcaa agtccatggg
     8881 tagaaaggat tgtgcaggta ttagatttag attatgaaga tttatttcgg aggtaactat
     8941 gaaaagaata attccagttt atatattcca acaagtaaat gtcctattgg tatctctata
     9001 cttattgaaa tttctttgta tcggtgagtt aactatacta cagattctct atggttcgtc
     9061 actcatttct tttttatgga tgtatggcca acgcaaacaa gcgcataagg tcaatatgaa
     9121 atctaggatg aaatggcttg gtgttgaatt tgttagccta ctgattataa gtctatgttt
     9181 tagtctgatt catgctcaag gaagcacgaa tcaagcaaac ttaattggcc ttcaacatca
     9241 aattccttgg ttttcatttt tattgttctt aatcaatgcg agtatggttg aagaatttct
     9301 gtatcgagaa attttatgga atttggtcag aaaattagat atcagagttg ctttgacaag
     9361 tgttttattt gccttagcac atcatacagg aaccattcta gcttggtgtt tgtatgtttc
     9421 acttgggatg tttttaggta tggtgcgcta taaatctgac ttatggggca gtatgggact
     9481 acatttggtg tggaacctac tagtttatag tttgctgctt ttttaaaata ggtgacctga
     9541 tttttaggta acttctaaaa ctaacttcca gttttgggag agagatggaa gttactttga
     9601 aaagttacgg aaacattatt ttctatgtga caacattgta taattgcttg cattttactg
     9661 gtggagagag tataatgagg gtggataaag tacttaatcc caaaaattta aataggagga
     9721 gctagctatg gcagaagaag tattaaatct tcaattagta tctgttcaag ttgacgaaac
     9781 agatgaagtt gatggaatgc gatttagtac attcagtaca aatcgttgcg gtaactggag
     9841 tgcttttagt tgggaaaatt gttaattcat ttaaattgta aactttagag attctctgga
     9901 gttatggatg tcgttccaat atgtgcacgt tggaatgtta gtgcttatat ggggagaatc
     9961 caaaggattc tcccttttta tttaaataag tctgtctagc tatagatata ttaagtttga
    10021 taaaatttct tggagatttt gttatggatt ataatttcaa tttggagcat cctttctttt
    10081 tcactaataa tgattatagt acagatacta gcataaagta ccaagtaagt ctgcctttta
    10141 attggcacga agtaatgaat aatgatgagt gggtttatca ataccctatt ggaaaatttg
    10201 ttgaaagaca agggtggaaa atacacatta gttcagagta taacagttca catgaattgt
    10261 tacaagatgt agcaaaaatt tgccatgaaa tgcgaattcc atttaaacat cttagtacag
    10321 aagacaaatt tatcatgcga aacgggaaat tggttagtcg aggattttct ggtaaattta
    10381 ttacatgtta tccaaatcaa aatgaattag agtcggtttt gcaaaggtta gaaagtgcct
    10441 taaagcaata taatgggcca tatattttaa gcgataaacg ttgggatgaa gcaccaatat
    10501 atctgaggta tggtgtgttt aggccgtcaa gggatgatga aaagaaggtt gctattgatg
    10561 aattaattgt tggcgatgaa gttgttaaag atgaacgttt accagtattt aaaattccaa
    10621 aaggtatagt gccccctgac tttttgaata aatggcttga caagaaagat aaaaaacagg
    10681 gagactttcc ctttattata gataatgcaa ttagattttc aaacagtggt gggatatata
    10741 atgctaggct aaaagaagat gggaaaaaaa taattttaaa agaggctaga ccgtatacag
    10801 gtctaggatt tgatggtact tattcttcag agaaattagc ttcggagtgc aaagcactaa
    10861 aaattctaaa tgaatggagt gagacgccta aaatatactg gcacggtaag atctgggagc
    10921 acaccttctt aggaattgaa catatgaagg gcgttccact aaatagatgg gttaccaata
    10981 attttccttt atatgaagtt gttgataaga ccaaagatta tctattgaga gtttcaaaga
    11041 tagtagaaaa actcatcgat ttaacgaata agtttcattc tgaaaatgta tatcatcaag
    11101 atttacattt aggaaatatc ttggttaagg atgaagatga gattagtata atagactggg
    11161 aacaggctgt cttttcaaat gatgaaaaag ttgtacataa agttgcagcc cctggtttta
    11221 gagcatggcg agaaacactt cccagtgaga tagattggta tggtattaga caaatagctc
    11281 attatttata catgccacta gtaactacat cggatttgac atacaactat gtaagtcaaa
    11341 ccaggataga aggaaaaaaa ctatttgagt ctttgggtta tacaagagaa catatagatt
    11401 atgtagaaag tttattgtca tatctagatt ctaaatgtcc acagattgag aatatttcca
    11461 ggaaaaaagt tttaaaatcc atgcatgaga ttagaactat cgagagtgag caagatatac
    11521 aagattttat tataaaatta ttgagagggt ttacgctaac ttatggacag tggcgtaaag
    11581 aatttcaatc aagattcttc ccagttcatt attatggtct gaattttaat caaggaattg
    11641 cgttttcaga tttagctatc ctttggagtt atcaacaact agctaagaaa gtaaaaaatt
    11701 tcaagtttga tgactattat gagattcgaa cacaggttat taatgaggca gtaaataatt
    11761 ttaagaaatc gtccctttct ggtctttttg atggtaaaat tggtacaatc tggctcattt
    11821 atgaatttgg ggagatagat cgggcagttg aactttttac aactcatttt atagagatat
    11881 ttgagaattc acaaaataaa aatttatata gtggacaggc tggaatttta ctggttggac
    11941 tgtattttct tagtaaaggg gaaattgata ataaactagg agaagaaata ctaattaggc
    12001 ttagagaata tactttaaat tatatagaaa atccagaaac tttttgtaaa gttggcgcta
    12061 gtgatgttca gagtaatgat ccttatgaga attttggtgg attactatat ggtcacgcag
    12121 gggtagcttg gctcttcggt gaagcttata aattaactgg tgaaagtatc tataaaaatg
    12181 gtctagaatt ggctgtagat aaagaattag ttgcttataa agtagatagt aataattcat
    12241 tgcagtacag ccaaggtcat agattactac catatctagc aactggaagt gctggcctgc
    12301 ttttacttat taatagaaat aaagaaatct tgtcaagcaa atacttaaaa tatttaactt
    12361 ctttagagag ggcaactgat gtagtttttt gtgtattacc aggtttattt aacggatttt
    12421 gtggtcttga agttgctaat aatatatata gtgatatcga tgataacttt tcaggacaaa
    12481 agaaattaat tgaacaactt tatagatatt tgtgtgtaat tgaagaagga tttgttattg
    12541 cgggagataa tggtttaaag ataacaacag atattgcttc gggatttgcg ggtgttgcaa
    12601 ttggattggt atcaataatg gataataaat tgacgattct tcctcaaata taatatttag
    12661 ataccattat taaggggtca tacttgtgaa tcagagtaat gaaatatttt taaatacaat
    12721 acaggaaaaa acacactata agaggtctat ctcttcatca tttcaggaat taaaaaaatg
    12781 gaattctttg atatttagga gagggcgata ttggtaccaa tttgataatt ggagtatacc
    12841 caatactggt gtaataaagg aatggtatgt cgaagataat gactggattc ctaaggttag
    12901 ttcttccagt ttagacaatt caaattcact taaaattgtc tttgatgtgg aaaaatatac
    12961 tttgccagat gatagtatct tacaggatgt taggatttca tctgatgaga gttatatagt
    13021 tttggttgta tcctcactgc gtagcactaa tttaattgga ataaaaaaat atactatgga
    13081 agagttattt atcattgaag atatttcagt agaaagttcg ttctatttgg gtaaattcgg
    13141 tgttatgtat actcgctcca aagagtacgg gaggccaagt aagttattct ataaatcttt
    13201 tgatagcttt acagaagagg aactgtttga agaaaacgaa tgctcttttc gattaaaaat
    13261 agtccacatt gatagcaata attgttttgt aaagtcagta gactttcaga aaggcaggat
    13321 ttttctatac agtttcgacc ggacgggttt tgttagacac tcttacacag aaacggtagc
    13381 cccaacacct agagatatcg ctctatttag tacagaaaaa gcacagtact ttcttgggat
    13441 ctcttcaact gaagaaaaga aagatcaact aattctaagg gaaacttctt cgggagacag
    13501 agtttctatt actataccat atcaagatag ggctagaaga gttcactgta taggacgtta
    13561 tatcctttta gactgttcaa acgcagcgaa ttccgtcttt tatcttgcta catttaaaaa
    13621 taatagtttg agggagttga gtgttaataa gataacattt gatgaaaaga caacacttta
    13681 tgaaaattca ttttctgatc gtgttcttct gtttttagag aggagaactt tttacgaaaa
    13741 aatacttagt tttgatttaa tagaaaatac attaaaaact gaatttgaaa gacccatcat
    13801 aaaatcgaat aatactaaat atttttctaa ggtgatttgg actaaaaaag acagttatga
    13861 tgtaagcata ccgatttctt tattttggaa aagtgaagat acggatgagc tcccaagaag
    13921 aaaaaaatgt attctaagtg tctatggggc ttatggtaag aatgataatt ctgatttaga
    13981 tgaaattatg ttatctataa tagatgcagg ttttatttat gctatagttc atgtaagagg
    14041 tggaggctat ttgggtggtg aatggtatcg ctcaggaaag gcgttaaaca aatggaattc
    14101 tatcagagat tttattgagg gagtaaatta tttaagggaa aatgatgtaa ttgacagtaa
    14161 gcgattaggt ttaataactt ctagtgcagg tggaataatt gctggtgcgg tgttgaacga
    14221 ggaaaaaaat ttattgcaaa gcattctctt attttcgcca tttataaatc cttatgatac
    14281 acttcagaat ccaaatgatc ctctttctaa gaccgaaata gcagagtggg gagatattag
    14341 agcccctgaa gtaaaggctt atataaagtc atattcgcct atgcaaaata ttgaaaaggc
    14401 acgagactca aatactgtta tagttaatat tttgggtgag aaagacccat atattaataa
    14461 taacgaagtg atagagtggt caaagaaatt aaattctatt ggagttaaaa gtttgttgta
    14521 tttaaacaaa gcagctgatc atggaggttt tactccatca gatgttctct taatgattga
    14581 tactttaaat tatttctttg aagaagtggg aaggaataac ttatgaatta tttaaaattt
    14641 ataaaaaaga ctaaacttat attaatgggg attttaatat ttctatcttc gtttaatggt
    14701 gtcttgctct caggaattat tgtatatgca ggtagtttaa atcagacttc ctcattttct
    14761 gacgttctaa gatttggtgc tataagtatt ctgggttggt cagcaatcta tatatcaaat
    14821 tactatttag aagtaacgga agcatcaata acgaaagata taaatgtaaa aattaaacaa
    14881 ggatatttta gagaacagta tctttcttct gaaatggtta aagattactc atctattatt
    14941 tcagttttgt caaatgattt gagattaatc gaagaaaact attttagaca aatttttgaa
    15001 ataatttctt caatattgtt gttcatcgtc tctctaagtt ttatgcttta tttaaacttc
    15061 ctagtttcaa taatatttat tgtattatca gcattgccga ttatagtacc tgtctttatg
    15121 aagaagatgt tgtctaattc agctaatgag tactctaaca gcaatgcaga gtatactcac
    15181 ataataaaag aaatttttaa tggttttaag acattaaaat cttattctgt tactaaagaa
    15241 ataattagtt tgtcggataa aaagttggat aaactagaag attctacttt taatttgaaa
    15301 cgatcagagg ttctttcaaa attggttgca gtactaattt caggtttttg ctttctagtt
    15361 cccttggttg taggatgtta ttttgtaatt tatcataaaa gcctttcttt tagtgaactg
    15421 ataggtattt tcttagcaaa cgataaagtt ttagggccga tacaatcaat tgcctattca
    15481 ttaaataaga taaatacaac caaagattta aggaaaccgt ttttaaaata cttaagtgga
    15541 gagaagaatt ttatagacgc tgaacatgat aataacggac tgtatacttc atcaatagat
    15601 gagatacaca tgaaagatgt tgtatattct attacaccag aaaataaatt aagtattgac
    15661 ttctcattta agtcaccatt tagggtatta ttaacaggaa cttctggtag tgggaaaaca
    15721 acgattttaa atttaattaa tggttcttta aagccacaaa aaggttatgt aaatttgtta
    15781 tcacatggga aaaagagttc agattcaata ccaacagttg atcagacacc atatattttt
    15841 gacactacta ttcgtgagaa cgtaacttta tttcaaaatg aatatttttc agatgatcag
    15901 ataattgagg tgttaaaaaa ggtaaatcta tatgaagaat tagaaaagat agatatacta
    15961 aattatcaat gtggtgaaaa tggtagtaat ttgtctggag gtcaaaaaca aaaaatagct
    16021 ttagctagag ctctgattag aaataataaa gtgtacttat ttgacgaaat atcagctaat
    16081 ttagataatg ataattcaaa ttccatacat gatattctgt tcaatttagg tatttcattt
    16141 attgaagttt cacatcatta tgacttaaat gacaagagat acactgatat atataaattg
    16201 gaaaatggaa cacttttcaa aattaagtga ttggaggcaa gaatatggat aaagattata
    16261 tattaaaagt gaaagggctg tatcatcaat ttttactagg aaataataaa acgttgcaag
    16321 tgctgaaaaa tgtttctctt tctgcttcga gaggagaatt tataagtatt ctaggaatta
    16381 gtggttctgg aaagtcaact ttattaaaat gtatttctag tttgcttgaa ccaacaagtg
    16441 gggaagtaat tttaaatgga atcaacccct ataaaatcag aaatgcaaaa ttgtcaagta
    16501 taagacgtaa cgaagtatct tttatatttc aagcatacaa tttaatacct tccctgccgg
    16561 taatagaaaa tatagcactt cctttgcgat tatcacaaaa aaaattaact attaaaaatg
    16621 tagaaaactt actcaaaaga atgaagttta atgctggctt aaacgatttt gttggaactc
    16681 tgtctggtgg agaacaacag aaggttgcta tagctagagc ggttattgct gatagtgata
    16741 taatatttgc tgatgagcca actggggctt tagacagcgt ttctcgtgaa gtaatttttg
    16801 aattattgag agagttagta ggggcgggta agtgtgtaat tatggtaacg cacgatatag
    16861 aattggcctc gaaaactgat cgtgcattaa tattgaaaga tggaaaaatt ttcaaagaac
    16921 ttcatagacc tagcggggaa gagttgtata aaatcttaga ggtacaatca actacggagg
    16981 aatagagatg ctcagattag tttactatca atttttacat aataagaaac aatggttagg
    17041 cgtttcacca gtaatttttg tttcgagttt agttatggga ttggctgtta atggggtaat
    17101 taatgttgag aataattcgc aagtatttgt cggacttcca gatcctaaac caatttttat
    17161 gtttccgata gtattcggag gagtaacatt attctttgtg ctctctaaca taataaatat
    17221 gttggttgaa atttttagag atgattacga acttctggag gtgttgggag caagtctcct
    17281 tcaactatca tttcttgtgg ggggacagat ttttatcatt tcctcgatta ttagttttat
    17341 tgcatatcta tgctctatat ttgttacgtc aaattattat tattttttac aatacttttt
    17401 cggggaaaat atattacctg atatccaatt tcaaacgagt gctgttggat gtatcattac
    17461 agtagtgttg atttcatttt tagcctttct aagtggttgc ttttatacgt tcaagaagat
    17521 tagaaatagg aagagttcta aaataaggca tgttctttca atagtaaaaa gaatactgct
    17581 attggctggt tttagtgtta tctggttgct ttctttgcaa caaattttcc aagatagcac
    17641 aattttagcg aaggcccaga taatattcaa tattgtaatc ttagatattg tgattattta
    17701 tcaattatct ccttttatac agtcatgttt tatcaaacta ctttctataa ttatatttag
    17761 aaataatttt atgttcattg tttcgaagtg gaatttacta tatcgtaagc cttatataaa
    17821 atctatcagt gctgcaatta caggagctat attactaatt tctagttttc aaatgatttc
    17881 tcagaatata ctatctcaat ttcaagatga cagtgattta gagctaaaag tggcatttat
    17941 tgtctatgta ggagcaccaa ttttgatagt acttgcaaat attatttcaa ttgcattttt
    18001 gtcatcgcat caagaaagga ttgagattca gcaatttgaa attttaggaa cttctaatta
    18061 ccagatggtt aagattaaag ttggtgaggc tatatttttg acatttgtta cttcattaat
    18121 tgcattttta cttaacatta aaattatggc tttaatatac tactctttag aggatatttt
    18181 aatagatgat atgaatcttt tggggttaat acttcc
//
LOCUS       DBEJJV010000041        18123 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.041, whole genome shotgun sequence.
ACCESSION   DBEJJV010000041 DBEJJV010000000
VERSION     DBEJJV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 18123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.041"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..507
                     /locus_tag="ACL3GT_001674"
                     /pseudo
     CDS             1..507
                     /locus_tag="ACL3GT_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            523..1020
                     /locus_tag="ACL3GT_001675"
                     /pseudo
     CDS             523..1020
                     /locus_tag="ACL3GT_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234238.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
     gene            1177..1602
                     /gene="lacA"
                     /locus_tag="ACL3GT_001676"
     CDS             1177..1602
                     /gene="lacA"
                     /locus_tag="ACL3GT_001676"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050044 - galactose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HGR0517312.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1633..2148
                     /gene="lacB"
                     /locus_tag="ACL3GT_001677"
     CDS             1633..2148
                     /gene="lacB"
                     /locus_tag="ACL3GT_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HGR0517313.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            2159..3088
                     /locus_tag="ACL3GT_001678"
     CDS             2159..3088
                     /locus_tag="ACL3GT_001678"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009024 - tagatose-6-phosphate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HGR0517314.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            3090..4070
                     /gene="lacD"
                     /locus_tag="ACL3GT_001679"
     CDS             3090..4070
                     /gene="lacD"
                     /locus_tag="ACL3GT_001679"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HGR0517315.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            4304..5140
                     /locus_tag="ACL3GT_001680"
     CDS             4304..5140
                     /locus_tag="ACL3GT_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HGR0517316.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5176..5493
                     /locus_tag="ACL3GT_001681"
     CDS             5176..5493
                     /locus_tag="ACL3GT_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0517317.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     DAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5495..7189
                     /locus_tag="ACL3GT_001682"
     CDS             5495..7189
                     /locus_tag="ACL3GT_001682"
                     /EC_number="2.7.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0019197 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase complex [Evidence IEA];
                     GO_function: GO:0015155 - lactose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose-specific PTS transporter subunit EIIC"
                     /protein_id="HGR0517318.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7404..8810
                     /gene="lacG"
                     /locus_tag="ACL3GT_001683"
     CDS             7404..8810
                     /gene="lacG"
                     /locus_tag="ACL3GT_001683"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HGR0517319.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8933..9112
                     /locus_tag="ACL3GT_001684"
     CDS             8933..9112
                     /locus_tag="ACL3GT_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HGR0517320.1"
                     /translation="MTSEELKSLGKWYVSTGKEWICHSDDELEEFKNLFLNFINPEEW
                     DTISFDSDFMPFQQS"
     gene            complement(9391..10152)
                     /locus_tag="ACL3GT_001685"
     CDS             complement(9391..10152)
                     /locus_tag="ACL3GT_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HGR0517321.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10440..11402)
                     /gene="nrdF"
                     /locus_tag="ACL3GT_001686"
     CDS             complement(10440..11402)
                     /gene="nrdF"
                     /locus_tag="ACL3GT_001686"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HGR0517322.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11590..13749)
                     /gene="nrdE"
                     /locus_tag="ACL3GT_001687"
     CDS             complement(11590..13749)
                     /gene="nrdE"
                     /locus_tag="ACL3GT_001687"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HGR0517323.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13830..14048)
                     /gene="nrdH"
                     /locus_tag="ACL3GT_001688"
     CDS             complement(13830..14048)
                     /gene="nrdH"
                     /locus_tag="ACL3GT_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HGR0517324.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
     gene            14399..14662
                     /locus_tag="ACL3GT_001689"
     CDS             14399..14662
                     /locus_tag="ACL3GT_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HGR0517325.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14668..16401
                     /gene="ptsP"
                     /locus_tag="ACL3GT_001690"
     CDS             14668..16401
                     /gene="ptsP"
                     /locus_tag="ACL3GT_001690"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HGR0517326.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16656..>18123
                     /locus_tag="ACL3GT_001691"
     CDS             16656..>18123
                     /locus_tag="ACL3GT_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HGR0517327.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT         5745 a         3232 c         3743 g         5403 t
ORIGIN      
        1 ggtttcaaga actcctctca gctctgagga cacggtaatg attgatgcga cggaagtaca
       61 aatcaatcgc cctaaaaaag aattagcgaa tgattctggt aaaaagaaat gccacgctat
      121 gaaggctcaa gcgattgtca caagtcaagg gagattgttt ctttggatat cactgtgaac
      181 tattgtcatg atatgaagtt gttcaaaatg agtcgcagaa atatcggaca agctggtaaa
      241 atcttggctg acagtggtta tcaagggctc atgaagatat atcctcaagt acaaactcca
      301 cgtaaatcca gcaaactcaa gccgctaaca gttgaagata aaacctataa ccatgcgcta
      361 tctaaggaga gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt taaaatgatt
      421 tcaacaacct atcgaaatca tcgtaaacgc ttcggattac gaatgaattt gattgctggc
      481 attatcaatc atgaactagg attctagttt tgcaggaagt ctaataaaga aactagcaag
      541 gtcaggcctt actttattgg tggacatcca ggatttaatt gtcctctact tgatgatgaa
      601 gtctatgaag attattatct agagtttgag aaagaagaga cttgctctgt tccacgtcct
      661 ttcccagaaa caggtatgtt ggatttccaa gatagaagtc catggctaga gggacaaaaa
      721 gaaatagatc ttagttatga tcttttcagc aaagatgcag tgactttgga tgaattgcaa
      781 tctcgaacaa ttgcccttcg ttctcttaaa catgataggg gattgaaagt gcattttgca
      841 gaatttccaa acctcatcat ctggtcaact ttgaacaagg gacctttcat tacctttgaa
      901 ccatggtctg gcttgtcaac attccttgaa gaaggagatc atttagaaga taagaagaat
      961 gtttgtctct tagaagccaa tcaggttgaa gaattagggt ttgagataga agttttataa
     1021 aaaagtaaaa aataaataac aaaaacaaac acaaactgtt gacttcttca aacaatagta
     1081 gtatattatg tttgtgagga ctaattgact gttttttaaa gacagccaat acactgctgg
     1141 aatccagcat agaaaaaata aaaaggagta tacaatatgt ctattgttat cggtgcagat
     1201 gctgcaggtt tgagattgaa agaagttgtg aaagacttct tagaaaaaga aaacttccac
     1261 cttgtggatg ttacagctga aggtcaagac tttgttgatg tgactctcgc tgttgctgca
     1321 gaagtaaaca aagaagaaca aaaccttggt atcgtgattg atgcttatgg agctggtcca
     1381 tttatggttg caactaagat caaaggaatg gttgctgcag aagtttctga tgaacgttca
     1441 gcttatatga ctcgtggcca caacaactca cgtatgatca ctatgggtgc acaacttgtt
     1501 ggtgatgaat tggctaaaaa catcgctaaa ggatttgtta atggtaaata cgacggtggt
     1561 cgtcaccaaa tccgggttga catgttgaac aaaatgggct aattagatta tagtaagaaa
     1621 ggtaagttaa aaatgagaat tgcaattgga tgtgaccaca tcgtaacaga tgaaaaaatg
     1681 gcggtttcag aatttttgaa atcaaaagga tatgaagtca ttgactttgg tacatatgac
     1741 catacacgta ctcactaccc aatctttggt aaaaaagtag gggaagctgt aactagcggt
     1801 caagctgatc ttggagtatg tatctgtggt actggtgttg gtatcaacaa cgctgtaaat
     1861 aaagttccag gtgttcgttc tgccttggtt cgtgatatga caacagccct ttatgctaaa
     1921 gaacaattga acgctaacgt tattggtttt ggtggtaaaa ttactggtga attgcttatg
     1981 tgtgatatca tcgaagcttt catccatgct gaatacaaac caactgaaga aaacaaaaaa
     2041 ttgattgcga aaattgaaca tgttgaaagt cacaatgctc aacaaacaga cgcaaacttc
     2101 ttcactgaat tccttgaaaa atgggatcgc ggagaatacc acgactaaga ggtaacctat
     2161 gattttaaca gttacaatga acccatccat tgatatttcc tatcccttgg atgagttgaa
     2221 gattgatact gtcaatcgtg tggtggatgt aaccaaaacg gctggtggta agggactcaa
     2281 tgttacccga gtactttcag aatttggcga ttctgttctt gctactggtt tagtgggtgg
     2341 caaacttggt gagtttttgg ttgaacatat cgataatcaa gtaaagaaag atttcttctc
     2401 aattcaggga gaaactcgta actgtatcgc tattctccac ggagacaacc aaacagaagt
     2461 tcttgaaaaa ggtcctgaag tattggaaca ggaaggtcaa gactttttgg aacatttcaa
     2521 aaaactcttg gagtcagttg aagtagtggc catctcaggt agtctgccag ctggccttcc
     2581 agttgattac tatgcgagct tggtagaact tgctaatcaa gctggcaagc ctgtagtctt
     2641 ggactgctca ggtgcagcac ttcaggctgt tcttgaatca ccccataaac caacagtcat
     2701 caaaccaaat aatgaagaat tgtctcagct tcttggaaga gaagtttctg aggatttgga
     2761 tgaattaaaa gaagtacttc aagaaccttt gtttgcaggg attgaatgga ttatcgtttc
     2821 acttggtgcc aacggtactt ttgccaaaca tggtgacact ttctacaagg tagatattcc
     2881 tagaattcag gtggtaaatc ctgttggatc tggagactct actgtggcag gaatttcttc
     2941 aggacttctt cacaaagaat cggatgcaga attactcatc aaggcaaatg tccttggtat
     3001 gctcaatgct caagaaaaaa tgactggtca tgtcaacatg gccaactatc aagttctata
     3061 tgatcaatta atagtaaaag aggtataaaa tggctttaac agaacaaaaa cgtgtacgct
     3121 tagaaaaact ttctgatgaa aatggtatca tctcagctct tgcatttgac caacgtggtg
     3181 ctttgaaacg cctcatggct caacaccaaa cagaagaacc aactgtggcc caaatggaag
     3241 aacttaaagt cttggtagca gatgaattga ctaaatacgc ttcatctatg cttcttgacc
     3301 ctgagtatgg acttccagca actaaagctc ttgatgaaaa agctggtctt ctccttgctt
     3361 atgaaaaaac aggttatgac acaacaagca caaaacgctt gccagactgc ttggatgtct
     3421 ggtctgcaaa acgtattaaa gaagaaggtg cagatgcagt taaattcttg ctttactatg
     3481 atgtagatag ctcagacgaa ctcaatcaag aaaaacaagc ctacatcgaa cgcatcggtt
     3541 ctgagtgtgt ggctgaagat atcccattct tccttgaaat tcttgcttac gatgaaaaaa
     3601 ttgcggatgc aggttctgta gaatacgcga aagtaaaacc acacaaagtt atcggcgcta
     3661 tgaaagtctt ttcagaccca cgctttaaca ttgatgtctt gaaagttgaa gttcctgtta
     3721 acattaaata tgttgaaggc ttcgctgaag gtgaagtagt ttatacacgt gaagaagcag
     3781 cagccttctt caaagcgcaa gatgaagcaa cgaacttgcc atacatctac ttgagtgctg
     3841 gtgtatcagc taaactcttc caagatactc ttgtatttgc tcatgaatca ggtgcaaact
     3901 ttaacggagt tctttgtggc cgtgcaacat gggctggatc agttgaagca tacatcaaag
     3961 atggtgaaac agcagctcgc gaatggcttc gcacaactgg atttgaaaac attgatgagc
     4021 tcaacaaagt tcttcaaaca acagcaactt catggaaaga acgtgtgtaa gaaagtcctc
     4081 ctagtttagg aacatgaatc taaaaaaatt taaaaaaagt tgtatgtaaa ggtttacaaa
     4141 ataacttact tgtgctatac ttaaatcaca agttaataca aggtgagtgt tactaagtaa
     4201 tattaggcat gatcacaggt gaattagaaa tcagctgatt ttctagttca tttgtggtca
     4261 ttttttgtac tcatatacct ttaagatata aaaggaggtt gacatgtatc gaattctaaa
     4321 tccaatgaat cacaatgtct cgcttgtcag aaatgataag ggagaagagg tgattgtaat
     4381 tggtaagggg attgcattcg gaaagaagaa gggggatttg attgctgaaa atcatgttga
     4441 gaaaatcttt cggatgaaga ccgaagagtc cagagaaaac tttatggctc ttctcaaaga
     4501 tgttccgctt gattttatca cagtgaccta tgaaatcatt gataagctat caaagaaata
     4561 tcattatccg attcaagagt atctctatgt aaccttgaca gatcatattt actgttctta
     4621 tcaagctcta actcaaggaa ggtacaagga tagtaatctg ccagatattt ctgctaagta
     4681 tcctgtcgct tttcaaatcg caaatgaagc ttttgaaatt tactgtcaga agctagcaga
     4741 tcattttcct gaggacgaaa ttattcggat tgcttatcat ttcattaatg ctgaaggtga
     4801 aaatgaagtg gaacttgtgg agtcgattga taagaggaaa gaaattctca ggaatgttga
     4861 agaagtttta acggactatg caattcaacg aactaaaaag aataaccatt tctatgatcg
     4921 ctttatgatc catttgaatt atttcttgga ttatttagac agatctagag atgataacca
     4981 atcacttctg gatatggaag atcatattaa acaatcctat ccaaaagcct tcgagattgg
     5041 ttccaagatc tatgatgtga ttacgcaaca tacgggtctt gatttgtata aaagtgaacg
     5101 agtttatcta gttctacata tccaacgttt attgtcataa aaatttattt aaaactatat
     5161 aaggagaatt ctatcatgaa tagagaagaa gtaacattgt taggttttga aatcgtagcc
     5221 tatgctggcg atgctcgttc aaaactattg gaagccttga aggctgctga agctggtgat
     5281 tttgaaaaag cggacgctct ggtagaggac gctggtagct gtattgcaga ggctcaccac
     5341 gcgcaaacaa gtctattgac taaggaagct tctggtgagg acttagcgta tagtgtgacc
     5401 atgatgcatg gtcaagatca cttgatgaca actatcttgt taaaagacct aatgcaccat
     5461 ttaattgaac tttacaagag aggagttaaa taaaatggat aagttaataa tttttattga
     5521 gaaaggaaag cctttctttg agaaattatc gagaaatata tacttaagag cgataaaaga
     5581 tggttttatt tccagtatgc cagcagtatt attctcaagt atttttatac taatagctgc
     5641 tgtgcccaat atttttgggt ttaaatggtc tgatgaacag ttagctttta ttttgaaacc
     5701 ttacaactac tcaatgggga ttttagctct cttagtagct gggacaactg caaaatcgtt
     5761 aacagattca gttaatacac gtagtatgga gaaaaccaac caaatcaact acatgtcaac
     5821 ttttttagca gctgttgttg gattgttaat actggcagct gatccaattg aaggtggatt
     5881 tgctaatggt cttttaggta ctagaggatt acttactgca tttttggcag cttttattac
     5941 agtaaatatc tataaagtat gtattaaaaa taatgtaacc attagacttc ctgaagaggt
     6001 tccaccaaat attgcacaag tttttaaaga tgttattccg tttgccttat ctgttctttc
     6061 aatatatgga ttggatttaa ttgttagaaa tatttttggt acaaatgtag cagaatctgt
     6121 tggtaaaata ttagcccctc tattttcagc tactgatggt tatatcggtt tagctattgt
     6181 atttggtgct tatgctttct tttggtttgt tggaattcat gggccatctg ttgtagaacc
     6241 tttaattgta gctatcagtt atgcaaatat agaagctaat gttcagcttg tgcaagctgg
     6301 tatgcacgca gataaaattt taaatccagt tactcaaact tttgttgtaa caatgggtgg
     6361 tactggtgca acactagtag ttccatttat gtttatgtgg ttatgtaaat caaaaagaaa
     6421 tagaattgtc ggacgtgcgt ctgtagttcc tactttcttt ggcgtaaatg aaccaatcct
     6481 atttggtgct ccaattgttt taaatcctat cttctttatt ccgtttgtta ctgctcctat
     6541 tatcaatgtt tggattatga aattttttgt agatgttcta caaatgaata gtttcagtat
     6601 tattttacct tggacaacac ctgctccaat tggtattgtt atgggaacgg cgctggctcc
     6661 attgtcattc gtcttggcta taactttaat cattatcgac actttaatct attatccatt
     6721 tgttaaagtt tatgaccatc aaattttaga agaagaacgg aaaggaaact cttcatctga
     6781 attgaaagaa aaagttgctg caaacttcaa cactgcaaaa gcggatgcta ttcttgaaaa
     6841 agcaggtgtc gatgcagcac aaaataccat cactgaagaa acaaatgtcc tcgttctctg
     6901 tgctggtgga ggtacaagtg gactccttgc aaatgctttg aataaggcag cagcagaata
     6961 caatgtccct gtgaaagcag cagcaggcgg ctatggtgct caccgtgaaa tgttaccaga
     7021 gtttgatttg gttatccttg ctcctcaagt tgcttcaaac tttgaagata tgaaggcaga
     7081 aacagataag ctcggtatta aactagcgaa aacagaaggc gctcaataca tcaaattaac
     7141 tcgtgatgga aaaggtgccc tagcattcgt acaagaacaa ttcgattaag gctaggaact
     7201 gtgaaacagt ctcctatcgt tacggaaatc gctatggcga atttcctaat cgccttatta
     7261 attcgtcggt aaaaagatat cgtttttacc tcctcatgtc acaattcggt gacttggtac
     7321 aagaagtgag atggagaagg atggctcact gactcctctc ctctcacttt tactttattt
     7381 aaatcaagaa ataggtgaaa aaaatgacaa aaacacttcc aaaagacttt atttttggtg
     7441 gcgcaacagc tgcctatcaa gcagaaggtg ctacacatac tgatggtaaa ggaccagtag
     7501 cgtgggataa atatcttgaa gataactact ggtacactgc agaaccagcc agtgattttt
     7561 acaatcgata tccagttgat ctcaagctag cagaagagta tggtgtcaat ggcattcgaa
     7621 tttctattgc ctggtcacgt attttcccga ctggttatgg tcaagtaaat gctaaaggtg
     7681 ttgagtttta tcataattta tttgcagagt gtcacaaacg tcatgttgag ccctttgtaa
     7741 ctcttcatca ctttgacacg ccagaagctc tccactcaaa tggagacttc ttaaaccgtg
     7801 aaaatatcga acattttgta gactacgctg ccttctgttt tgaagaattt ccagaagtaa
     7861 actattggac aaccttcaat gaaattggac caatcggtga tggtcaatat ttggttggga
     7921 aattccctcc aggtatccag tacgaccttg ccaaagtctt tcaatcacac cacaatatga
     7981 tggtgtctca tgcatgcgcg gtaaaattgt acaaagagaa aggctataaa ggggaaattg
     8041 gtgttgttca cgccctgcct actaaatatc ctctagatcc tgaaaatcca gcagatgttc
     8101 gtgcagcaga gttggaagat atcatccaca ataaattcat cttagacgca acttatctag
     8161 gtcgctattc agctgaaacc atggaaggtg tcaaccatat cttatcagtc aatggtggta
     8221 gtttggatct tcgtgaagaa gattttacag cattagaagc tgcaaaagac ttgaatgatt
     8281 tcctaggaat caactactat atgagtgact ggatggaagc ctttgatgga gaaactgaaa
     8341 ttatccataa tggtaaaggt gaaaaaggaa gctctaagta tcaaatcaaa ggtattggtc
     8401 gtcgtgtagc tcctgactat gtatcacgca cggattggga ttggattatc taccctcaag
     8461 gtttgtatga ccaaatcatg cgtgtgaaga aagattatcc taactacaag aagatttaca
     8521 tcactgaaaa tggtctcggc tataaagatg agttcgttga taacactgtt tacgatgatg
     8581 gtcgtattga ttacgtgaaa caacacttgg agatcttgtc tgatgcgatt gcagatggag
     8641 ctaatgtaaa aggttacttc atttggtcat taatggatgt cttctcatgg tcaaacggtt
     8701 atgagaaacg ttatggtctc ttctacgtag attttgaaac tcaagaacgt tatcctaaga
     8761 aatcagctca ctggtacaag aaagtagcgg aaactcagat tatagactag tagaattagt
     8821 cattagatat agaattttag tgagtcaaaa agatgttcaa agattttatc caatctattt
     8881 atgaaaaaaa gtttatatta taaatttcga aaaatgctct caaataccgt gtttgacgag
     8941 tgaagaattg aaaagtcttg gaaaatggta tgtctcgact ggtaaagaat ggatttgtca
     9001 ttcagatgat gagctggaag aatttaaaaa tctattttta aattttatca atcctgaaga
     9061 atgggatact atctcctttg attcagattt tatgccgttt caacaatcgt aaccaatttc
     9121 tcaaaaaagt taaatcttat atttagtact ctgtaaaact cttatctaat cacgttgctt
     9181 atactcaatg aaaatcaaag agcaacttta aactaggaag cgagtcgcag atttctcaat
     9241 gcatagcttt gaggaattgg gcaaaaagtc tttgatatag aaaaaagcat agtatcaggt
     9301 gttgaaacac ctgatactat gctttttatt gtgggaagat ttactttttt tcttctgaaa
     9361 ttgagttgtt acccaggctc tttcagttta ttaaggcttg atgactttaa tgtgtttaga
     9421 tagcttaaaa aggattgaat cacttagttt agaatctgaa acaatagtat caagatttga
     9481 tatattataa aaagtataaa aatcaaactt attgaactta ctatgatctg cgagtaaata
     9541 ttttttatta gaattattta aagcgatgcg ttgagcctct ccctcttcct cgctaaaagt
     9601 agctagagct ccgttttgaa taccattaca gctaacgaaa gctttagaaa attggagatt
     9661 agagagattt tgtagggtca atgtgccaac aaaagcacct gtaatatcgc gataatttcc
     9721 acctatcaaa atcaaatctg ttaattttcg ttcgcttaaa atcagaaaaa caggtagact
     9781 gttggttacg acgcggatat tgtcaatagg caactcacgc gcaaaaaact ctaatgttgt
     9841 tcctggtcca atgaaaatag tttctctttc ttctactaga ctgcctgcaa aatgggctat
     9901 ttcttgtttt tctgccgttt ggagggcttg tttttcaata tttgatcgct cattagtcaa
     9961 aagggagttg gttcgaagtt tttcagctcc accatgcaca cgaatcagca aatctttatc
    10021 agctaattcc tgtaaatagc gccttgcagt catatctgaa acggctattt cgtccataat
    10081 ctgtttaact gttatggttc ctttactatt tactatctct aaaattttgg ttaatttttc
    10141 ttgtttgagc atattatcac ctcgtttcct actactatct taccataaac aaactcatca
    10201 ttcaaataca aaaacaacaa aatgaaacaa aaacaaaaat atcgaagttt gttttcaaaa
    10261 ctttcgatat ttttgttggg ttattatttt gttgtttcta gtttactttt tgatggttaa
    10321 gagtggtgga gaattatact caatgaaaat caaagagcaa actaggaagc tagccgcagg
    10381 ctgtacttga gtacggcaag gcgaagctga cgtggtttga atttgatttt cgaagagtat
    10441 tagtccaaac cgtagttgta gtcatcatct tgcatggctt caacttcgcc aagaaggtaa
    10501 ccatttccga cttgagagaa gaagtcatgg ttggaagttc ctgttgaaat accgttcata
    10561 acgattgggt tgacatcttc agctgaatct gggaaaagtg gatcttgtcc catgttcatg
    10621 agagctttat tggcattgta gcgaaggaag gttttaacct cttcagtcca accaacaccg
    10681 tcataaagac tctctgtgta gccttcttca ttttcataaa gagtatagag taggtcgtac
    10741 atccattctt tgagtttttc ttgctcttct tcaggtaatt cattgaaacc aagttggaat
    10801 ttgtaaccaa tgtaggttcc gtgaacagac tcgtcacgaa taatcaattt aatgatttct
    10861 gcaacgttgg caagtttgtt gttaccgaga tagtagaggg gagtgaagaa accagagtag
    10921 aagaggaagg tttcgaggaa gacgctggca actttctttt caagtgggct gccgtttagg
    10981 tagatttcgt tgacaatctc agccttcttt tgtaggtaag gattggtatt ggtccattcg
    11041 aaaatttctt caatctcagc cttagtattc aaggtagaaa agattgatga gtaagattta
    11101 gcgtggacag attccataaa ttggatgtta ttgaaaacag cttcctcatg tggtgtacgg
    11161 atgtctgcgc gaagggcttg aaccccagtt tcagattgca tagtgtcaag aagggttaaa
    11221 ccaccaaaaa cttttccgac caagtctttc tctttgttag atagctttct ccagtcatcc
    11281 aagtcgtttg ataagggaat acgtgtatcg agccaaaatt gctccgtcag tttttcccaa
    11341 gttgatttgt cgatgacatc ttcgatggca ttccagttaa tggctttgta gtaagtttcc
    11401 atttaaaatc tctttctgtg tttagtattg cgaactcaca attatttcta ctttaccata
    11461 attctatagg agtatcgcac aaaaagtcgg aagcccgact tttaaaatgt tacataaatt
    11521 atgttatgac atagtagatt tgattttatc agtgctgctt agggaaaaat agtgtttcta
    11581 tgctagaaac taaatcacac agctttcaca ttggttggcg ccgacttctc caccgtcatc
    11641 tgtaaaggta cggacgtagt agatagactt gattcccttg ttaaaggcat agttacgaag
    11701 gatggacaag tcacgtgtcg tttgtttatt ttccctcttc cattcgtaaa ggccttttgg
    11761 aatgtcacta cgcatgaaga gggtgagtga aagtccttga tccacgtgtt cagtcgcagc
    11821 agcgtaaaca tcgatgactt tacgcatatc catatcgtag gcagaagtgt agtaaggaat
    11881 ggtttctgta gacaagccag cagcagggta gtagatttta ccaattttct tttcctgacg
    11941 ttcttcaata cgttgcgtaa tcgggtggat agaagcagaa acatcgttga tgtagctgat
    12001 agaaccattt ggcgctacag caaggcgatt ttggtggtaa agaccatcct cttgaacctt
    12061 gtcgcgaagt tcagtccaat cagcaacacc agggataaaa acatttttga agagttcttt
    12121 aacacggtct gatgttggaa caaattcacc agttacatac ttgtcaaagt aacttccgtt
    12181 agcatagtct gatttttcaa agttgtggaa ggtaatacca cgttcacgcg caatattgtt
    12241 tgactctacc aaggtccagt agttcataag cataaagtag atgcttgtaa attcaacaga
    12301 ctcaggtgaa ccatattcaa tgagttgttg ggcaaggtag ctgtgcagtc ccatggcacc
    12361 gagaccaaag gtgtgggctt ggctatttcc atggtcaatc gttggtacag ctacgatatg
    12421 tgaactatct gtaacgaaag taagggcacg aaccatagca cggatagaac gaccaaaatc
    12481 aggtgaagtc atcatgttaa ccacgttggt tgaacccagg ttacatgaaa catctgttcc
    12541 catttgaagg aattcttgag catcgttgat caagcttggt tcttgaactt gaagaatctc
    12601 agaacacaag ttactcatga taatctttcc atcgacagga tttgcacggt tagccgtatc
    12661 tatgttgact acataaggat agccagactc ttgttgcaat ttagagattt cagtttccaa
    12721 atcccgcgcc ttgatttttg tcttgcgaat atttggattt gcgaccaatt catcgtattt
    12781 ttcagtaatg tcgatgtaat tgaatggcac accgtattct ttttctacag agtaagggct
    12841 gaagaggtac atttcttcat ttttacgagc caattcgtag aatttatcag gtactacaac
    12901 accaagtgat agagtcttga cacgtacttt ttcatcagcg ttttctttct tagttgaaag
    12961 gaaagcgatg atatctgggt gaaagacgtt gaggtagaca acaccggcac cttgacgttg
    13021 ccccaattgg ttggagtaag agaagctgtc ttcaaaaagc ttcataacag gaacgacacc
    13081 tgaagcagct ccttcatagc ctttgatagg tgcaccagct tcacgaaggt tgctgagggt
    13141 aattcccaca ccaccaccaa tacgtgaaag ttgaagagct gagttgatag aacgtccgat
    13201 agagttcata tcatccgtca cttggattag gaaacaagat accaactccc cacgacgagc
    13261 acgtccagca ttcaagaagg aaggagtagc aggttggtag cgttggtgga tgatttcatt
    13321 ggcaatatcg attgcaacag cttcattccc atcagcgaaa taaagggcgt tgaagaagac
    13381 acggtcttcc atattttcaa gatagtattc accgtcatta gtctttaagg catattgatt
    13441 gtaaaattta taagctgcca tgaatgactt gaattggaag ttttggtctt tgataaattg
    13501 agccaattct tccaagaact ctggacggta tttcttgata aaggctgttt cgatgtagtt
    13561 gtgttcaatg aggtaattga ttttgtcttt gattgaatca aaaaccatag tgtttggaac
    13621 tacattttct ttaaagaaag catccaaggc ttccttatct ttatgaagca tgatttgtcc
    13681 attaacagga cggttaattt cgttattaag acggaagtaa gtcacgtctt caagatgttt
    13741 taatcccata aaatttccct tatctaatta caaaagaaag gcttctaagt tagccctaaa
    13801 agcagtttct tctggatgat gtactaagat tatgctaatt gtttcagttt ttctggttgg
    13861 aaacctgaaa agacttcagt tggtgtttgg ataacaggag ctgcgctaaa accgagctct
    13921 ttaacttgat cgacgtactc aggttgctca tcaagattga tttcacgata agagacatta
    13981 ttactgtcca agaaacgctt ggtcatttta cattggacac aattgttttt agaataaacg
    14041 gttaccattg tgtaactcct cttcaaaatt taatactatc ttagtatatc agaaaataaa
    14101 attttgtcaa tgatttaaac taaatatagt ggtgttcttt tgttgttttt atatataaac
    14161 acaatatata gtgtttgtat tgtgaaatag caatgattat cctataaatt gtttttgaag
    14221 aaactatatc ctgtgttttg ttatctagga tagaagattt tcagcaagtt atctgaaagg
    14281 aaattgaagg aaaatccaga aaatgcttga aaaaaatcct agaagatggt ataatactaa
    14341 attgtaaggg ttatcacata taactcaaaa aaagaaagaa caaaaggaga gtcaaactat
    14401 ggcttctaaa gatttccacg tagtggcaga aacaggtatt cacgcacgtc cagcaacatt
    14461 gttggtacaa actgctagca aatttgcttc agatatcact cttgagtaca aaggtaaatc
    14521 agttaacctt aaatcaatta tgggtgttat gagtcttggt gttggtcaag gtgctgacgt
    14581 aactatctca gctgaaggtg cagatgcaga tgacgctatc gctgcaatct cagaaacaat
    14641 ggaaaaagaa ggattggcat aagggaaatg acagaaatgc ttaaaggaat cgcagcatct
    14701 gacggtgttg cagttgcaaa agcatatcta ctcgttcagc cggatttgtc atttgagact
    14761 attacagtcg aagatacaaa cgcagaagaa gctcgccttg atgccgctct acaggcatca
    14821 caagacgagc tttctgttat tcgcgagaaa gcagtaggta cgctcggtga agaagcagct
    14881 caagtttttg atgctcactt aatggttctt gctgacccag aaatgatcag ccaaatcaag
    14941 gaaactatcc gtgcgaagaa agtgaatgca gaagcaggtc tgaaagaagt tacagatatg
    15001 tttatcacta tctttgaagg catggaagac aacccataca tgcaagaacg cgcagcggat
    15061 atccgcgacg tgacaaaacg tgtattggca aaccttcttg gtaaaaaatt gccaaaccca
    15121 gcttctatca atgaagaagt gattgtgatt gcgcatgact tgactccttc agatacagct
    15181 caattggaca aaaactttgt aaaagctttt gtaaccaaca ttggtggacg tacaagccac
    15241 tcagctatca tggcacgtac acttgaaatt gctgctgtat taggtacaaa caacatcact
    15301 gaaatcgtta aagacggtga catccttgct gttaacggga tcactggaga agtgattatc
    15361 aacccgacag atgaacaagc ggcagaattt aaagcagctg gtgaagccta tgcgaaacaa
    15421 aaagctgaat gggcactttt gaaagatgct caaacagtga ctgctgacgg taaacacttc
    15481 gagttggctg ccaatattgg tactccaaaa gacgttgaag gtgttaacaa caacggtgca
    15541 gaagctgttg gactttaccg tacagagttc ttgtacatgg attctcaaga cttcccaact
    15601 gaagatgagc agtatgaagc atacaaggct gttcttgaag gaatgaacgg taaacctgtt
    15661 gtcgttcgta caatggatat cggtggagat aaggaacttc cttacttcga tatgcctcac
    15721 gaaatgaacc cattccttgg attccgtgct cttcgtatct ctatctctga gactggagat
    15781 gctatgttcc gcacacaaat ccgtgctctt cttcgtgcgt ctgttcacgg tcaattgcgt
    15841 atcatgttcc caatggttgc gctcttgaaa gaattccgtg cagcgaaagc agtctttgat
    15901 gaagaaaaag caaaccttct tgctgaaggt gttgcagttg cggataacat ccaagttggt
    15961 atcatgatcg agattcctgc agcggctatg cttgcagacc aatttgctaa agaagttgac
    16021 ttcttctcaa ttggtacaaa cgacttgatc caatatacaa tggcagcaga ccgtatgaac
    16081 gaacaagttt cataccttta ccaaccatac aacccatcaa tcctacgctt gattaacaat
    16141 gtgatcaaag cagctcacgc tgaaggtaaa tgggctggta tgtgtggtga gatggctggt
    16201 gaccaacaag ctgttccact tcttgtcgga atgggcttgg atgagttctc tatgtcagca
    16261 acatctgtac ttcgtacacg cagcttgatg aagaaactcg acacagctaa gatggaagag
    16321 tacgcaaacc gtgcccttac agaatgctca acaatggaag aagttcttga acttcaaaaa
    16381 gaatacgtta attttgatta atcgaaaagt ccctgcaact cagttacagg gacttttttt
    16441 gatattttaa aaagaatttt caagaaaatc tttcttataa aaagtccaac cttgaaaaag
    16501 tagtggtcag aacaaaaaat acttaaatgg ttcataaaat tcttgacaag ttggagattt
    16561 aggagtaaac tattaaccag ttaagtaata gagaggagtt tctgcaattt agaaatgaat
    16621 tgcaactaga aatatcaaat agaaagagag tttcgatgaa aattaataag aaataccttg
    16681 ttggttctgc ggcagctttg attttaagtg tttgttctta cgagttggga ctgtatcaag
    16741 ctagaacggt taaggaaaat aatcgtgttt cctatataga tggaaaacaa gcgacgcaaa
    16801 aaacggagaa tttgactcct gatgaggtta gcaagcgtga aggaatcaat gctgagcaaa
    16861 tcgtcatcaa gataacagac caaggctatg tcacttcaca tggcgaccac tatcattatt
    16921 acaatggtaa ggttccttat gatgcgattt tcagtgaaga attactcatg aaagatccaa
    16981 actataagct aaaagatgag gatattgtta atgaggtcaa gggtggatat gttatcaagg
    17041 tagatggaaa atactatgtt taccttaagg atgctgccca cgcggataac gtccgtacaa
    17101 aagaggaaat caatcgacaa aaacaagaac atagtcaaca tcgtgaaggt gggactccaa
    17161 gaaacgatgg tgctgttgcc ttggcacgtt cgcaaggacg ctatactaca gatgatggtt
    17221 atatctttaa tgcttctgat atcatagagg atactggtga tgcttatatc gttcctcacg
    17281 gcgaccatta ccattacatt cctaagaatg agttatcagc tagcgagtta gctgctgcag
    17341 aagccttcct atctggtcgg ggaaatctgt caaattcaag aacctatcgc cgacaaaata
    17401 gcgataacac ttcaagaaca aactggctac cttctgtaag caatccagga actacaaata
    17461 ctaacacaag caacaacagc aacactaaca gtcaagcaag tcaaagtaat gacattgata
    17521 gtctcttgaa acagctctac aaactgcctt tgagtcaacg ccatgtagaa tctgatggcc
    17581 ttgttttcga cccagcgcaa atcacaagtc gaaccgccag aggtgtagct gtccctcatg
    17641 gtaaccatta ccactttatc ccttatgaac aaatgtctga attggaaaaa cgaattgctc
    17701 gtattattcc ccttcgttat cgttcaaacc attgggtacc agattcaaga ccagaacaac
    17761 caagtccaca atcgactccg gaacctagtc caagtctgca acctgcacca aatcctcaac
    17821 cagctccaag caatccaatt gatgagaaat tggtcaaaga agctgttcga aaagtaggcg
    17881 atggttatgt ctttgaggag aatggagttt ctcgttatat cccagccaag gatctttcag
    17941 cagaaacagc agcaggcatt gatagcaaac tggccaagca ggaaagttta tcgcataagc
    18001 taggagctaa gaaaactgac ctcccatcta gtgatagaga attttacaat aagacttatg
    18061 acttactagc aagaattcac caagatttac ttgataataa aggtcgacaa gttgattttg
    18121 agg
//
LOCUS       DBEJJV010000042        17837 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.042, whole genome shotgun sequence.
ACCESSION   DBEJJV010000042 DBEJJV010000000
VERSION     DBEJJV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 17837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17837
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.042"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            48..121
                     /locus_tag="ACL3GT_001692"
     tRNA            48..121
                     /locus_tag="ACL3GT_001692"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:82..84,aa:Met,seq:cat)
     gene            125..197
                     /locus_tag="ACL3GT_001693"
     tRNA            125..197
                     /locus_tag="ACL3GT_001693"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:158..160,aa:Phe,seq:gaa)
     gene            210..290
                     /locus_tag="ACL3GT_001694"
     tRNA            210..290
                     /locus_tag="ACL3GT_001694"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Tyr,seq:gta)
     gene            295..365
                     /locus_tag="ACL3GT_001695"
     tRNA            295..365
                     /locus_tag="ACL3GT_001695"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:327..329,aa:Trp,seq:cca)
     gene            380..452
                     /locus_tag="ACL3GT_001696"
     tRNA            380..452
                     /locus_tag="ACL3GT_001696"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:413..415,aa:His,seq:gtg)
     gene            466..537
                     /locus_tag="ACL3GT_001697"
     tRNA            466..537
                     /locus_tag="ACL3GT_001697"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:498..500,aa:Gln,seq:ttg)
     gene            547..630
                     /locus_tag="ACL3GT_001698"
     tRNA            547..630
                     /locus_tag="ACL3GT_001698"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:581..583,aa:Leu,seq:caa)
     gene            737..2014
                     /locus_tag="ACL3GT_001699"
     CDS             737..2014
                     /locus_tag="ACL3GT_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HGR0517328.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     MKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2090..3574
                     /gene="thrC"
                     /locus_tag="ACL3GT_001700"
     CDS             2090..3574
                     /gene="thrC"
                     /locus_tag="ACL3GT_001700"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004795 - threonine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009088 - threonine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HGR0517329.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPDTYPKVDLNF
                     DKLKDASYQEVAKLVLSAFLDDFTVEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFANVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3635..4915
                     /locus_tag="ACL3GT_001701"
     CDS             3635..4915
                     /locus_tag="ACL3GT_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HGR0517330.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4919..5539
                     /locus_tag="ACL3GT_001702"
     CDS             4919..5539
                     /locus_tag="ACL3GT_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0517331.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5705..6817
                     /locus_tag="ACL3GT_001703"
     CDS             5705..6817
                     /locus_tag="ACL3GT_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HGR0517332.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7140..7565
                     /locus_tag="ACL3GT_001704"
     CDS             7140..7565
                     /locus_tag="ACL3GT_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HGR0517333.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7576..7935
                     /locus_tag="ACL3GT_001705"
     CDS             7576..7935
                     /locus_tag="ACL3GT_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HGR0517334.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8042..8686
                     /gene="pcp"
                     /locus_tag="ACL3GT_001706"
     CDS             8042..8686
                     /gene="pcp"
                     /locus_tag="ACL3GT_001706"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR0517335.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVK
                     AGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH"
     gene            complement(8714..9571)
                     /locus_tag="ACL3GT_001707"
     CDS             complement(8714..9571)
                     /locus_tag="ACL3GT_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HGR0517336.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9701..10843
                     /gene="tgt"
                     /locus_tag="ACL3GT_001708"
     CDS             9701..10843
                     /gene="tgt"
                     /locus_tag="ACL3GT_001708"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HGR0517337.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10941..12758
                     /locus_tag="ACL3GT_001709"
     CDS             10941..12758
                     /locus_tag="ACL3GT_001709"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HGR0517338.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12911..14062
                     /gene="nagA"
                     /locus_tag="ACL3GT_001710"
     CDS             12911..14062
                     /gene="nagA"
                     /locus_tag="ACL3GT_001710"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HGR0517339.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14225..15283
                     /locus_tag="ACL3GT_001711"
     CDS             14225..15283
                     /locus_tag="ACL3GT_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HGR0517340.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15434..15799
                     /locus_tag="ACL3GT_001712"
     CDS             15434..15799
                     /locus_tag="ACL3GT_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HGR0517341.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            15875..16816
                     /gene="comGA"
                     /locus_tag="ACL3GT_001713"
     CDS             15875..16816
                     /gene="comGA"
                     /locus_tag="ACL3GT_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HGR0517342.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            16764..17780
                     /gene="comGB"
                     /locus_tag="ACL3GT_001714"
     CDS             16764..17780
                     /gene="comGB"
                     /locus_tag="ACL3GT_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HGR0517343.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
BASE COUNT         5192 a         3173 c         4150 g         5322 t
ORIGIN      
        1 gtaaaagcgt gcgtgggttc gaatcccaca tcctcctttt atattaacgc gggatggagc
       61 agctcggtag ctcgtcgggc tcataacccg aaggtcgtag gttcaaatcc tgctcccgca
      121 ataaggctcg gtagctcagt tggtagagca atggattgaa gctccatgtg tcggcggttc
      181 gattccgtct cgcgccattt atatattttg gaagggtagc gaagaggcta aacgcggcgg
      241 actgtaaatc cgctccttcg ggttcggggg ttcgaatccc tccccttcca ttttacgggc
      301 atagtttaaa ggtagaacta aggtctccaa aaccttcagt gtgggttcaa ttcctactgc
      361 ccgtgttaat agaattatgg cgggtgtggt gaagtggtta acacaccaga ttgtggctct
      421 ggcatgcgtg ggttcgatcc ccatcactcg cctattttat attattgggg tatagccaag
      481 cggtaaggca agggactttg actccctcat gcgttggttc gaatccagct accccagtta
      541 ctatttgccg gcgtggcgga attggcagac gcgctggact caaaatccag tgtccgcaag
      601 gacgtgccgg ttcgaccccg gccgccggta tagtatagtg ttaggaacgt tgttattctt
      661 cgttcctttt ttatattatt tttggtataa ttatagttat tcaaatttta tttagattaa
      721 gaaagtgtag gggagtatgt cttgttctat cgatttatta aaacatcggt atttgaaaaa
      781 tattaaagaa aatcctgaat tgtttgtcgg aattgagttg gagtatcctg ttgcaagttt
      841 agaaggggat gctacagatg ttgaagttat gaaggatcta tttcattatt tagtttctac
      901 tttggatctc accgtagcaa aggtagatga ttttggcaat ctgatccagt tagtagatcc
      961 gataagtcag gatgctattt tatttgaagt ttcctataca acgattgagt ttgcatttgg
     1021 taaggctgaa acgattcaag aggtcgaaaa tcgtttcaat aattatatga atgtaattca
     1081 gagaaagtta gctgaatcaa atcatgctat tgttggctgt ggtatccatc ccaactggga
     1141 taaaaatgag aattgtccag tggcttatcc acgctatcag atgttgatgg attatttgaa
     1201 tttgagtaga aatattatta aatcagattt acatcatttc cctgaatatg gtacttttat
     1261 ctgtgggagc caggttcagc tggatatttc aaaaaccaac tacttacggg tgattaatgc
     1321 ttttactcaa attgaagcgg ctaaggctta tttatttgca aactctgaat tttcgggtgc
     1381 ggattgggat acgaaaattt caagggatat tttctgggaa gaatctatgc atggtatcta
     1441 tccagagaat gttggggtca atgctagact ccttaatgat gaagctgatt tttttgacta
     1501 tctaaatcat tctgcgattt ttactgcgga acgtgatggg cagacctatt atttttatcc
     1561 tattcaggct ggggactatt tggctacgtc cgaaatccaa gcatttgctc tgaatgggga
     1621 tgaggttatt atttaccccc aagagaagga ttttgaaact catcgtagtt accagtacca
     1681 agatttaacg actcgaggaa cagttgagtt tcgtagtgtg tgtacacagc cacttgatag
     1741 gacttttgct tctgcagctt ttcacttggg attattggtt aatttagaca agttagaagc
     1801 ttacttagaa acagcacctt tctttaaagt atttggttat gattacaagt ctttaaggag
     1861 acaattttct aagaaaaatc ttacagatga ggaagaaact acgattattg aattttccaa
     1921 agacttactc ctactagctg aggagggact agtggtgaga aataaggaag aaatgaccta
     1981 tttacagcct ttgagagaag aattgagcct ataatttctc ttataaaggg agaattttct
     2041 gaaaaatcat gatataatgg acgagactat agataaagga tagagagtaa tgacattagt
     2101 ttatcaatca acgcgtgatg ccaacaatac agtaactgcc agccaagcaa ttttgcaagg
     2161 tttggcgacg gacggcggtt tgtttacacc ggatacttat ccaaaggtag atttgaactt
     2221 tgacaaattg aaagatgctt cttaccagga agttgctaag ctagttttgt cagcattttt
     2281 agatgacttt acagttgagg agttggacta ctgtatcaac aatgcctacg atagcaaatt
     2341 tgatactcca gctattgcac cattagtgaa attagatggg caatacaatt tggaactttt
     2401 ccatggttca acgattgcct ttaaggatat ggccttgtct attttgccat actttatgac
     2461 gactgctgct aagaaacatg gtttggagaa caagattgtt atcttgacag cgacatctgg
     2521 tgacacgggg aaagctgcta tggcggggtt tgcgaatgtg cctggtactg agattatcgt
     2581 cttttatcca aaggatggtg tcagcaagat tcaagagtta caaatgacca ctcagactgg
     2641 cgacaatact catgttattg ctattgatgg taactttgac gatgcgcaaa caaatgtgaa
     2701 gcacatgttt aacgacgtgg ctcttcgtga aaaattgact accaacaagt tgcaattttc
     2761 atcagctaac tctatgaaca ttggtcgtct ggtgccacaa attgtttatt atgtttatgc
     2821 ttacgctcaa ttggttaaga ctggtgaaat tgtagctggt gaaaaggtta acttcacagt
     2881 accaacagga aactttggaa atatcttggc tgccttttat gccaaacaaa ttggtttgcc
     2941 agttggtaaa ttaatctgtg cttcaaatga caacaatgtt ttgacagact tctttaaaac
     3001 acgtgtctat gacaaaaaac gtgagtttaa ggtaacaacc agcccatcta tggatatctt
     3061 ggtatcttca aacttggagc gcttgatttt ccatcttttg ggaaataatg ctgaaaagac
     3121 aactgaactt atgaatgcct tgaacacgca aggacaatat aagttgacag actttgatgc
     3181 agagattttg gacctctttg cagctgaata tgcgactgag gaagaaacgg cagcagagat
     3241 caagcgtgtt tgtgagttag attcttatat cgaggaccct catacagctg ttgcttcagc
     3301 agtttataaa aaataccaat cggccactgg agatgtaact aagacagtga ttgcttcaac
     3361 agctagtcca tacaagttcc cagtagttgc agtagaagct gtaactggaa aagcaggttt
     3421 aacagacttt gaagccttgg ctcaattaca tgaaatctca ggcgttgcag tgccaccagc
     3481 agttgatggg cttgaaatag ctccaattcg tcacaagaca acagtggcag ctgctgacat
     3541 gcaagcagcg gttgaggctt atttaggact ttaagacaga gggagcaaac tcggttggga
     3601 aaccaactga gtttcttttc atcaggagga gagattgttt aagaaaaata aagacattct
     3661 taatattgca ttgccagcta tgggtgaaaa ctttttgcag atgctaatgg gaatggtgga
     3721 cagttatttg gttgctcatt taggattgat agctatttca ggggtttcag tagctggtaa
     3781 tattatcacc atttatcagg cgattttcat cgctctggga gctgctattt ccagtgttat
     3841 ttcaaaaagc atagggcaga aagaccagtc gaagttggcc tatcatgtga ctgaggcgtt
     3901 gaagattacc ttactattaa gtttcctttt aggatttttg tccatcttcg ctgggaaaga
     3961 gatgatagga cttttgggga cggagaggga tgtagctgag agtggtggac tgtatctatc
     4021 tttggtaggc ggatcgattg ttctcttagg tttaatgact agtctaggag ccttgattcg
     4081 tgcaacgcat aatccacgtc tgcctctcta tgttagtttt ttatccaatg ccttgaatat
     4141 tcttttttca agtctagcta tttttgttct ggatatgggg atagctggtg ttgcttgggg
     4201 gacaattgtg tctcgtttgg ttggtcttgt gattttgtgg tcacaattaa aactgcctta
     4261 tgggaagcca acttttggtt tagataagga actgttgacc ttggctttac cagcagctgg
     4321 agagcgactt atgatgaggg ctggagatgt agtgatcatt gccttggtcg tttcttttgg
     4381 gacggaggca gttgctggga atgcaatcgg agaagtcttg acccagttta actatatgcc
     4441 tgcctttggc gtcgctacgg caacggtcat gctgttggcc cgagcagttg gagaggatga
     4501 ttggaaaaga gttgctagtt tgagtaaaca aaccttttgg ctttctctgt tcctcatgtt
     4561 gcccctgtcc tttagtatat atgtcttggg tgtaccatta actcatctct atacgactga
     4621 ttctctagcg gtggaggcta gtgttctagt gacactgttt tcactacttg ggacccctat
     4681 gacgacagga acagtcatct atacggcagt ctggcaggga ttaggaaatg cacgcctccc
     4741 tttttatgcg acaagtatag gaatgtggtg tatccgcatt gggacaggat atctgatggg
     4801 gattgtgctt ggttggggct tgcctggtat ttgggcaggg tctctcttgg ataatggttt
     4861 tcgctggtta tttctacgct atcgttacca gcgctatatg agcttgaaag gataggaaat
     4921 gcaaaaaaca gcttttattt gggatttaga cgggacttta ttggactctt acgaagcgat
     4981 tttatcaggg attgaggaga cttttgctca gttttctatt ccttatgata aggagaaggt
     5041 gagagagttt atcttcaagt attcggtgca agatttgctt gtgcgggtgg cagaagatag
     5101 aaatctggat gttgaggtgc taaatcaggt gcgtgcccag agtctggctg agaagaatgc
     5161 tcaggtagtt ttgatgccag gtgcgcgtga ggtgctagct tgggcagacg aatcaggaat
     5221 tcagcagttt atatatactc ataaggggaa caacgctttt accattctca aggacttggg
     5281 ggtggaatcc tattttacag agattttaac cagtcagagt ggctttgtgc ggaagccaag
     5341 tccagaagcg gctacctatc tgctagataa gtatcagttg aattctgata atacttatta
     5401 tataggggat cggactctgg atgtggaatt tgcccagaat agtgggattc aaagcatcaa
     5461 ctttttagag tctacttatg aagggaatca caggattcaa gcgttagcag atatttcccg
     5521 tatttttgag actaagtgat aaaaagattg tgtcagtttt gtgacagaga cctaacaaac
     5581 tatttcaagt aacctagttt gttacaagga atagacagtt ctgttaaata ggcccgagag
     5641 ggcttttttt ctacattttt tgtgttatga tagacaggta ctcatttgaa aggaatttga
     5701 aagaatgaag aaaagaatgt tattagcgtc aacagtagcc ttgtcatttg ccccagtatt
     5761 ggcaactcaa gcagaagaag ttctttggac tgcacgtagt gttgagcaaa tccaaaacga
     5821 tttgactaaa acggacaaca aaacaagtta taccgtacag tatggtgata ctttgagcac
     5881 cattgcagaa gccttgggtg tagatgtaac agtgcttgcg aatctgaaca aaatcactaa
     5941 tatggacttg attttcccag aaactgtttt gacaacgact gtcaatgaag cagaagaagt
     6001 aacagaagtt gaaatccaaa cacctcaagc agactctagt gaagaagtga caactgcgac
     6061 agcagatttg accactaatc aagtgaccgt tgatgatcaa actgttcagg ttgcagacct
     6121 ttctcaacca attgcagaag ttacaaagac agtgattgct tctgaagaag tggcaccatc
     6181 tacgggcact tctgtcccag aggagcaaac gaccgaaaca actcgcccag ttgaagaagc
     6241 aactcctcag gaaacgactc cagctgagaa gcaggaaaca caagcaagcc ctcaagctgc
     6301 atcagcagtg gaagtaacta caacaagttc agaagcaaaa gaagtagcat catcaaatgg
     6361 agctacagca gcagtttcta cttatcaacc agaagagacg aaaataattt caacaactta
     6421 cgaggctcca gctgcgcccg attatgctgg acttgcagta gcaaaatctg aaaatgcagg
     6481 tcttcaacca caaacagctg cctttaaaga agaaattgct aacttgtttg gcattacatc
     6541 ctttagtggt tatcgtccag gagacagtgg agatcacgga aaaggtttgg ctatcgactt
     6601 tatggtacca gaacgttcag aattagggga taagattgcg gaatatgcta ttcaaaatat
     6661 ggccagccgt ggcattagtt acatcatctg gaaacaacgt ttctatgctc cattcgatag
     6721 caaatatggg ccagctaaca cttggaaccc aatgccagac cgtggtagtg tgacagaaaa
     6781 tcactatgat cacgttcacg tttcaatgaa tggataaacc cgacttgata acatcatttt
     6841 gacgaatgag atctagcttt cgtgatggaa agcgattctc gttcgttttt tctttgtcat
     6901 actcttcgaa aatctcttca aaccacgtca gttttatctg aaacttcaaa gctgtgcttt
     6961 gagcaacctg cgactagctt cctagtttgc tttttgattt tcattgagta tcaatttgaa
     7021 tggaaaatgg aaagttatca tcttgtaatg agttaagcaa cattcttgca atctatttta
     7081 ctttatatca caattaatta gtcaaatatt gataaatcaa taaaaagaga ggggaagaaa
     7141 tgctagagat tcaagattta ctgtatcaac tccgcttgtc tgagcaagcg agtacgcaat
     7201 tgtttgaaaa aaggcttggg attagtttga cacggtatca gattttactg tttttgctgg
     7261 agcattctcc ttgtaaccaa atggcggttc aggagcgttt gaaaattgat caggctgctt
     7321 tgacacggca tttcaaaatt ttggaaacgg aaggtttggt ggagcgtcat cgtaatcctg
     7381 aaaatcagcg ggaagtgttg gtagaggctg cgaagtatgc caaggagcag ttagtggtga
     7441 atccccctct gcaacatatc agggttaagg aagagataga aagtatctta acagagtttg
     7501 agagaacaga actcagccgt ttattaaata aattggtttt gggtattgaa aatatagaaa
     7561 tttaaggaga aatagatgtc aattatttta acaacgatcg ttgctttgga gcatttttac
     7621 attttttatt tggaaagtat tgccacgcaa tcagatgcga ctagtcgtgt atttaatatg
     7681 gaaaaggaag aattggctca tccgtcagta agttcattgt tcaaaaatca aggaatttat
     7741 aaggctctgc taggagtctt tctcttgtat gtcatttatt tctcacagaa tttagaaatt
     7801 gtgactattt ttgtcttatt tgtgattggt gctgcgactt acggctcttt aacagcggat
     7861 aaaaaaatta ttttgaaaca aggtggatca gctattttgg ccttgattag tattttactc
     7921 tttaaataca cttgaaggtc gattctaatc tcgctaatcc tttttaatcc agaataaggg
     7981 aaatatgtta tacttgtttt taagaaaaaa gtctcattga attggttttg aggagttaga
     8041 aatgaaagta ttagtgacag gttttgagcc ctttggaggg gaaaagggca atccagcttt
     8101 ggaggccatt aaaggtttac cagctgaaat ccatggtgct gaggtccgtt ggctagaggt
     8161 gccgacagtt tttcacaaat ctgctcaagt attggaagaa gagatgaatc gttatcaacc
     8221 tgactttgtc ctttgtattg ggcaagctgg tggaagaact agtttgacac ctgaacgagt
     8281 gaccattaat caagacgatg catgcatttc tgataacgaa gataatcaac cgattgaccg
     8341 tcccattcgc ccagatggtg cttcggccta ctttagtagt ttgccgatta aagcgatggt
     8401 tcaagctata aaaaaagagg gcttaccggc ctctgtttcc aatacggcag ggacttttgt
     8461 ctgcagccat ttgatgtatc aggctctcta tttggtagaa aagaaatctc catatgttaa
     8521 ggcaggtttt atgcatattc cttatatgat ggaacaggtg gtgaacagac cgactactcc
     8581 agctatgagt ttagtggata ttcggcgagg gatagaagca gcaatcggcg ctataataga
     8641 acatggagat caggaactca agttggtagg cggagaaact cattgataga aaaaagcttg
     8701 aggagaaaaa ccttcaagct tttggacgtt ttcgggccaa tactgctcgg taaaacataa
     8761 ttttagtgca ttggatataa ggtaggagtg aaaaactagc aatgccaaag gtaatccaat
     8821 tgaggaagta ccaaggaaga agctgtaaat ctaggacaaa gtgctggaac ttgtagccct
     8881 tcataaagga acggctagtt tttaggattc gtcttggtgg gacctgtcct aggtctagac
     8941 tataacagag aagaaattcc acctgtgaat aggcataata ctgtggaata tagaggatat
     9001 ttcctacaat gatcaagatg agacttgcaa gaaagtagag tccaaagacc atgaggaaac
     9061 gctcggtttc aactgatgag agatctagat ttggaaactc aggatgtagg gtgacgaatt
     9121 ttttggctaa aaagctacta taaaagagga ggtaaatccc aagtaaatta gggatactcc
     9181 ataaaaagag atagaaacgt ttgagaagta gggtcaaaaa ggtttgagaa aagcgctcct
     9241 catcaaagag agctaggctg ttttttacag atggctccgt tttagaatct ttcatgagtg
     9301 tcagtgttgc atagacggaa ctggtcaaaa gaatagtccc gataaaggag actagtagag
     9361 gaaagaggta ggtttgaagt atttggccaa gtatgctgaa aaatggctgt tctaaaacag
     9421 tcccgtggat ccgagataag ggattaagaa aaccagataa gatgaccagc atactgggaa
     9481 ggatatagag gagaaagaga cggggggtgt cagcctgaaa atgttttgac tcctgacgaa
     9541 ttgtttttaa atcaattttt ggatagttca ttctcttatt ataccatagt tcttatacat
     9601 agttcgtgac agttcctact ttttttgata aaatcataca gtgtgtcctt gggcacactg
     9661 tatgaactgg gactgtcttt cccagcttcg gaggtaaaaa atgtcagatt caccaatcaa
     9721 atatcgtttg attaagaaag aaaaacacac aggagctcgt ctgggagaaa tcatcactcc
     9781 ccacggtacc tttccgacac ctatgtttat gccagttggg acacaagcca ctgtcaaaac
     9841 tcagtcacct gaagaattga aggagatggg ttcgggaatt atcctatcaa acacctatca
     9901 tctctggctt cgccctggag atgaactcat tgcacgcgct ggtggtctcc acaagttcat
     9961 gaattgggac cagcctatct tgacagatag tggtggtttt caggtttatt ctttagcaga
    10021 tagccgtaat atcacagaag aaggagtaac ctttaaaaat catctaaatg gttctaagat
    10081 gttcctatcc ccagaaaaag ccatctctat tcagaataat ctgggttcag acatcatgat
    10141 gtcctttgat gaatgtcctc agttttatca accttatgac tacgttaaga aatcgatcga
    10201 gcgtaccagc cgttgggctg agcgtggttt gaaggctcac cgtcgtccac atgaccaagg
    10261 tttgtttgga attgtgcaag gtgcaggatt tgaagacctt cgccgccaat cagctcatga
    10321 tcttgtcagc atggatttct caggctactc tatcggtggt ttggcagtgg gagaaaccca
    10381 tgaagagatg aatgcggtct tggactttac aactcaactg ctacctgaaa ataaacctcg
    10441 ttatctgatg ggtgtgggag cgccagatag cttgatcgat ggggtcattc gtggggtgga
    10501 tatgtttgac tgtgtcttac cgactcgaat tgctcgtaac gggacttgta tgaccagtca
    10561 aggacgtttg gttgtgaaaa atgcccagtt tgctgaggac tttacgccac tggatcctga
    10621 gtgtgactgc tacacatgta ataactatac acgcgcttac cttcgtcacc tgctcaaggc
    10681 tgatgaaacc tttggtatcc gcttgactag ctaccacaat ctttacttct tgcttaacct
    10741 gatgaagcaa gtgcgacaag ccatcatgga tgacaatctc ttggaattcc gtgagtattt
    10801 tgtggaaaaa tatggctata ataagtcagg acgtaatttc taaaatggaa ttgatataaa
    10861 aaaatcctaa gttttctctt aggatttttc ttcttttttt gatagaataa agtgtacaat
    10921 gaaaggaaga ataaactcgt atgcgcatta aatggttttc cttgattagg attataggtt
    10981 tacttttggt actcttgtat cacttctttc agacgatctt tcctggagga tttttcgggg
    11041 tagatgtctt tttcacattt tcaggtttcc tgattacagc tctactcatt gaagaatttt
    11101 ctaagaacaa tgagattgat ttgataggat tttttagaag acgcttttat cggattgtgc
    11161 cacctgtggt tttgatggtc ttggtgacca tgccttttac tttcttggtt cgccaagact
    11221 atgttgctgg aattggtggc cagattgcgg gcgtcttagg ctttatgacc aacttctatg
    11281 aactcctaac aggtgggagt tatgaatctc agttcattcc tcatttgttt gttcataatt
    11341 ggagtttggc agttgaggtt cactactata ttctttgggg attggcagtt tggttcttat
    11401 ccaaacaagc taaatcaaat ggtcagttga aggggatggt ctttctctta tctgctgctg
    11461 ccttcttgat cagtttcttc tccatgttta ttggtagttt tctagtgacc tcttattcct
    11521 ctgtttattt ctccagttta actcatgtct atccattctt tttgggaagt atgttagcaa
    11581 ctattgtagg tgttcgtcag acgacttccc tcgtcaagca gttggataaa atctgggatt
    11641 tacgaaagac tttggtagtt tttggaggag gctttggttt cctagttctt ttgactttct
    11701 ttgtcaaatt cacttatctt tttgcctatc ttatcggctt cttgcttgcc agtcttgcag
    11761 ctcttgccat gattctggcg gcgcgtgtct tacatgaaaa gacacatcat atacaggagc
    11821 cgaagattat cagcttttta gcggatacta gctatgcggt ttatcttttc cattggcctt
    11881 tctatatcat tttctcacag ttgacatcaa atcttcttgc tgtattactg actctgattt
    11941 gttcttatgg ctttgccagt ctgtcattct atgtattgga accttggatt gcaggcaaga
    12001 acacacctat tttacaaact cttcgtcccc tgccttatat tcacgcaatt cttgtagcag
    12061 gtacaggaat cttgaccatc attgtctgca cggtgacctt gttggcacca caagtgggag
    12121 cgtttgagac agacttgact gtcaatggct tgaagcaagc tgcaacaaat attggccaga
    12181 ccaaggtgat ggcagaacgg gcagatgcaa acagtttggg aattgctgat ggcactatgt
    12241 taattggtga ctcagtggct ttaagggcaa atacagcact acagacagct cttcctggag
    12301 cacagattaa cgcgcaggtc agcgtaacaa ccaagaccgc aaatgaaatc atgctaaata
    12361 atagccagaa taaattttta cctaagacgg tggtcattgc gactggggta aataatcctg
    12421 agaattacaa ggatgactgg gacagtatcg tgaaaaatct tcctaaggga caccatatga
    12481 ttttggtgac tccttatgag ggagataaga caaaagagac ctatgccatc gttgagaagg
    12541 ctgctgccta tatgagagaa ttggcagaga agacacctta cattacgata gcagattgga
    12601 atcaagttgc gaaagagcat ccagaaattt gggctggaac agaccaggtt catttcggga
    12661 gtgagagtag cactatcgaa gcaggagcaa aattgtatgc agatacgatt gccacagctt
    12721 tgcagacagc tcaagacaag ccggttaaat caaaataact tgtattaaaa aagagaagag
    12781 ttggagaaat ccagctcttt taaaatatct ccaaaaaata ggtctatacc atttacaaat
    12841 aaaaaagaaa ggtttataat gtaattgaca taataaattg tagaatcaat cttttaagga
    12901 ggttaacatt atgcctaact atattaaagc ggatcagttt ttctacccac acggagttcg
    12961 tcgaggtggt tacttggaac ttgtggacgg caagtttggg aaacatgtag agcagattcc
    13021 tgaaggggct gaggtgattg actatacagg ttatagcatt gccccaggtc ttgtggatac
    13081 tcatattcat ggatatgcag gtgtagatgt gatggacaac aacattgaag gtacattgca
    13141 tactatgagt gaaggacttc ttagtaccgg tgttaccagt ttcttaccca caactttaac
    13201 agccacttat gagcaattgc ttgcagtcac tgaaaatctt ggaaaccatt ataaagaagc
    13261 aacaggtgct aagattcgtg ggatttatta tgaaggtcca tatttcacag aaacttttaa
    13321 gggggcacaa aatccaactt atatgagaga cccgggtgtt gaggagtttc attcttggca
    13381 aaaagcggca aatggcttgc ttaataaaat tgcccttgca ccagaacgtg atggggtgga
    13441 agactttgtt cgtacagtta cgggcgaagg tgtgacggtt gctcttggac attcaaacgc
    13501 gacttttgat gaagccaaaa aagcagtcga tgctggagcg agtgtttggg tgcatgccta
    13561 taatggaatg cgtgggttga ctcaccgtga attgggtatg gttggagcca tgtaccaatt
    13621 gccacatacc tatgcagagt tgatctgtga tggtcaccac gtagatccaa aggcttgcga
    13681 aattcttatc aaacaaaaag gaacagaaaa catcgctctt atcacagact gtatgacagc
    13741 tgggggattg gaagacggag attatatgtt gggagaattc ccagttgtcg ttgcaaatgg
    13801 aactgcacgc ctcaaatcga caggtaactt ggcaggttct atcctcaaac tcaaagatgg
    13861 tttgaagaat gtggtcgaat ggggaattgc gaatccgcat gaagcagtca tgatggccag
    13921 cttcaaccca gctaaatccg ttcacatcga tgacgtctgt ggccaaatcc gtgaaggcta
    13981 cgacgctgac ttcatcgtat tagataaaga tttggaattg gtagcaacct atctagatgg
    14041 cgtaaaacgt tatcaagcat aagagagaag gcagaagtta gagactagct tctgcttttt
    14101 tatacagggt actttactgg taaataaaaa gttaaaaaaa tcacaaaaaa agcttgaaga
    14161 aacaaagaaa aaggcttaca attgaactat aaatattaca aataaaaaaa cggaggagtg
    14221 ctttatgaaa gcctatactt atgttaaacc aggacttgct tcttttgttg atgtagacaa
    14281 accagttatt cgcaagccaa cagacgctat tgtgcgtatt gtaaaaacca ctatttgtgg
    14341 aacagacctc catattatca aaggggatgt tcctacttgc caaagtggta ccattcttgg
    14401 ccacgaaggg attgggattg ttgaagaagt tggggaagga gtttccaact tcaaaaaagg
    14461 cgacaaggtc ttgatttctt gcgtctgtgc ctgtggtaaa tgctactact gtaaaaaagg
    14521 aatttatgcc cactgtgaag acgaaggggg ctggattttc ggtcacttga ttgatggtat
    14581 gcaggctgaa tatctacgtg tccctcatgc agataatact ctttaccata ctccagaaga
    14641 cttgtcagat gaagctttgg ttatgctgtc agacattctg cctactggat atgaaattgg
    14701 tgtcttaaaa gggaaagtag aacctggttg cagcgtagcc attattggtt caggtccagt
    14761 tggattggct gctcttttaa cagcccaatt ctattcacca gctaaattga ttatggtaga
    14821 cctagacgat aaccgcttgg aaactgccct atcattcggt gcgactcata aggttaattc
    14881 ttcagaccct gaaaaagcca ttaaagaaat ttatgatttg acagatggtc gtggtgtgga
    14941 tgtcgctatc gaagctgttg gtattcctgc aacatttgat ttctgtcaaa agattatcgg
    15001 tgtagacgga acggttgcca actgtggtgt gcatggtaaa ccagttgaat tcgatttaga
    15061 taaactttgg attcgcaaca tcaatgtaac aactggtttg gtatctacaa atacgactcc
    15121 acaattgttg aaagcacttg aaagtcataa gattgaacca gaaaaattgg taactcacta
    15181 tttcaaactc agtgaaattg aaaaagccta tgaagtcttc agtaaggcag cagaccacca
    15241 tgccattaag gtcattatcg aaaacgatat ctcagaagcc taagtagtaa aaatattttt
    15301 gtacataagt aaatagaaat tcagtcatcc atcagatggc tggatttttt atcaaaaaat
    15361 taagaaatga gcatatttct ttccttgtct ggcggaattg gttataatat acggtacaaa
    15421 ggaatgaatg aatatgtatc gtgttataga aatgtacgga gattttgaac cgtggtggtt
    15481 cttagaaggt tgggaagaag atattgtagc aagtagaaaa tttgaccagt attatgatgc
    15541 tctcaaatac tacaaaactt gctggtttag attggaacaa gaatcccctc tttataaaag
    15601 tagaagcgac ttgatgacca ttttttggga cccggaagac caacgctggt gtgatgaatg
    15661 tgatgagtat ttacaacaat accattcttt ggctcttttg caggatgagc aggttatccc
    15721 agacgaaaaa ctacgctcag gctatgaaaa acaaaccagt caggaaagga atcgttcttg
    15781 ccgtatgaaa ttaaaataga gaaaagtaac ttttttggag ttgctttttt tatttttcta
    15841 acgctttgcg aatagtatag gtgaggaggt aagtatggtt caagaaattg cacaagaaat
    15901 cattcgttca gctcggaaaa aagggacgca ggatatttat tttgtcccta agttagacgc
    15961 ctatgagctt catatgaggg taggagacga gcgctgtaaa attggtagct atgattttga
    16021 aaagtttgca gccgttatca gtcactttaa gtttgtggcg ggtatgaatg tgggagaaaa
    16081 aagacgtagt caactgggtt cctgtgatta tgcctatgac cagaagatgg cgtctctacg
    16141 tttatctact gtaggcgatt atcgggggca tgagagtttg gttatccgtt tgttgcacga
    16201 tgaggagcag gacttgcatt tttggtttca ggatattgaa gaattaggca agcagtacag
    16261 gcaacgggga ctctatcttt ttgctggtcc ggttgggagt ggtaagacga ccttgatgca
    16321 tgaattgtcc aagtcactct ttaaaggaca gcaagttatg tccatcgaag atcctgtcga
    16381 aatcaagcag gacgacatgc ttcagttgca gttgaacgaa gcaatcggcc taacctatga
    16441 aaatctaatc aaactttcct tgcgtcatcg accagatctc ttgattatcg gagaaattcg
    16501 tgacagcgag acggcgcgtg cagtggtcag agctagtttg acaggtgcga cagtcttttc
    16561 aaccattcac gccaagagta tccgaggtgt ttatgagcgt ctgctggagt tgggtgtgag
    16621 tgaagaagaa ttggcagttg ttctgcaagg agtctgctac cagagattaa tcgggggagg
    16681 aggaatcgtt gactttgcaa gcagagatta tcaagaacac caagcagcca agtggaatga
    16741 gcaaattgac cagcttctta aagatggaca tatcacaagt cttcaggctg agacggaaaa
    16801 aattagctac agctaagcaa aaaaatatca tcaccctatt taacaatctc ttttctagcg
    16861 gttttcatct ggtggagact atctcctttt tagataggag tgctttgttg gacaagcagt
    16921 gtgtgatcca gatgcgtgcg ggcttgtctc aggggaaatc attctcagaa atgatggaaa
    16981 gtttgggatg ttcaagtacc attgtcactc agttatctct agctgaagtt catggcaatc
    17041 ttcacctgag tttgggaaag atagaagaat atctagacaa tctggccaag gtcaagaaaa
    17101 agttaattga agtagcgacc tatcctttga ttttgctggg ttttcttctc ttaattatgc
    17161 tggggctacg gaattacctg ctcccacaac tggatagtag caatattgcc acccgaatta
    17221 tcggtaatct gccacaaatt tttctaggca tggtagggct tgtttccgtg cttgcccttt
    17281 tagcactaac tttttataaa agaagttcta agatgagtgt cttttctatc ttagcacgcc
    17341 ttccctttat tggaatcttt gtgcagacct acttgacagc ctattatgca cgtgaatggg
    17401 ggaatatgat ttcacaggga atggagctga cgcagatttt tcaaatgatg caggaacaag
    17461 gttcccagct ctttaaagaa atcggtcaag atctggctca aaccctgaaa aatggccgtg
    17521 aattttctca gacgatagga acctatcctt tctttaggaa ggaattgagt ctcatcatag
    17581 agtatgggga agttaagtcc aagctgggta gtgagttgga aatctatgct gaaaaaactt
    17641 gggaagcctt ttttacccga gtcaaccgca ccatgaattt ggtgcagcca ctggttttta
    17701 tctttgtggc actgattatc gttttacttt atgcggcaat gctcatgccc atgtatcaaa
    17761 atatggaggt aaatttttaa aatgaaaaaa atgatgacat tcttgaaaaa agctaaggtt
    17821 aaagctttta cattggt
//
LOCUS       DBEJJV010000043        15651 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.043, whole genome shotgun sequence.
ACCESSION   DBEJJV010000043 DBEJJV010000000
VERSION     DBEJJV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.043"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(105..1529)
                     /locus_tag="ACL3GT_001715"
     CDS             complement(105..1529)
                     /locus_tag="ACL3GT_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HGR0517344.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2074..4353)
                     /gene="pulA"
                     /locus_tag="ACL3GT_001716"
     CDS             complement(2074..4353)
                     /gene="pulA"
                     /locus_tag="ACL3GT_001716"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051060 - pullulanase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HGR0517345.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4465..6423)
                     /gene="ligA"
                     /locus_tag="ACL3GT_001717"
     CDS             complement(4465..6423)
                     /gene="ligA"
                     /locus_tag="ACL3GT_001717"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HGR0517346.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVADSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KVSQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSISKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6516..7694)
                     /locus_tag="ACL3GT_001718"
     CDS             complement(6516..7694)
                     /locus_tag="ACL3GT_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0517347.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LNMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7774..8637)
                     /locus_tag="ACL3GT_001719"
     CDS             complement(7774..8637)
                     /locus_tag="ACL3GT_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0517348.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDATYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQKAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8640..10541)
                     /locus_tag="ACL3GT_001720"
     CDS             complement(8640..10541)
                     /locus_tag="ACL3GT_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HGR0517349.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGEDLDKLLSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKYSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(10947..12173)
                     /locus_tag="ACL3GT_001721"
     CDS             complement(10947..12173)
                     /locus_tag="ACL3GT_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HGR0517350.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICMINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(12245..12910)
                     /locus_tag="ACL3GT_001722"
     CDS             complement(12245..12910)
                     /locus_tag="ACL3GT_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysostaphin resistance A-like protein"
                     /protein_id="HGR0517351.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVTGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVVWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEEIIHRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(12977..13177)
                     /locus_tag="ACL3GT_001723"
     CDS             complement(12977..13177)
                     /locus_tag="ACL3GT_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HGR0517352.1"
                     /translation="MLNLQFAETMELTEAELEIVYGGEFGNNAVIPAGAWGGFGTPWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            complement(13463..14326)
                     /locus_tag="ACL3GT_001724"
     CDS             complement(13463..14326)
                     /locus_tag="ACL3GT_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HGR0517353.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNIISELMERKLFSYIPIFE
                     AELESMLRPYDVFEKVLWQFLKKMSIFLQTKGSNQKEIEHFIQSLQVLENPQLIALFE
                     LRLQQYKKLID"
     gene            complement(14722..>15651)
                     /locus_tag="ACL3GT_001725"
     CDS             complement(14722..>15651)
                     /locus_tag="ACL3GT_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HGR0517354.1"
                     /translation="PTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPFGFSN
                     KLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHSTA
                     NIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPRI
                     GNFYNNLSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKP
                     KIVGIYKLGMKYNSDNYKESAILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFEL
                     FTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
BASE COUNT         4921 a         3289 c         2726 g         4715 t
ORIGIN      
        1 gtttcaatct attataatac caaaaagttc gtattttttc tataattatt attattttat
       61 agcaaaaaaa taaaaccagg aaaacaattt cctggtttta cacgttattt cacatcaaaa
      121 acaatggatt tgacatttgt catcgcttca atgctatatt taattccttg cactccagct
      181 ccagaacctt tgacaccaag gaatgggaaa ttatctggac cacgctgggt tttattatta
      241 atgtggactg tacctacttc aagtttttca gcaatttcaa aggctttttt gaaatcattt
      301 gtaaagactg atgattgaag gccgaattca gattcgttgg caaaggcaat agcttcctct
      361 acactagcca cacgaatgat tggtaaaaca ggaccaaatg gctcttccca tgccactttc
      421 atatcttttg taacttggtc aaaaagcact ggccagagaa gattgccctc acgtttgatt
      481 ggtgtaagag cctgagcttc tttttcttgt gcatcctcaa tcaagcccca aatgaagtcg
      541 gctgaagcat tgtcaataac aggtgtaata tcagcattgt caaatggatc accaactgtt
      601 aatttagaaa cttcttcctg aagcaaagta gctaatttat ctgctacact ttcgagaaca
      661 atgacacgtt taatggccgt gcaacgttgt cctgagtagc taaaggctcc cgcaacaatt
      721 tgcttggcag catgttccaa atctgcatct tctagtacaa gagctgcatc tttcccacca
      781 agttccaaca tgataggacg cataccagct aaacgaccaa tacgttctcc aataggagtt
      841 gaacctgtaa agttgatgaa gttgacttct ttgtgctcaa tgatataatc cccaatttct
      901 gaaccacgac ctgtaatggt gttgaaaaca cctgccggaa tccctgcttc ttcaaatgct
      961 ttagccaaca agagtccaga aatggaacct tgtgttggtg gcttaaacat gaccacattc
     1021 cctgcaatca aggcaggtgc aattttagaa gcagataaat taactggata attaaaggga
     1081 gcaatcgcta gcacgatacc aactggttca cgacggacaa cagccagttt gtttttactt
     1141 gctgcctcaa aaccaccacc ttccattgct tgtccagtga tacggagacc ttcctcagca
     1201 gcataacgaa tcaagtctgc tgtacgcact acttctccaa ttgctgcttt aatccctttt
     1261 gctacttctt tggcaaggat agtaccaatt tcttccttat cgcgttctaa aatagctgct
     1321 gttttatgta aataagccgc acgttcaact gctgataaag ctcgccatgc tggcagggct
     1381 gcacgcgcag cttgcatagc ctcatcagct tcagtctgag tcatggctgg aactgtaccc
     1441 aattcttctt gattgattgg tgaataaatc gtaatttctt gttcagatga tttccatttt
     1501 ccatttacta aattctgata tcttgtcaaa ttcttgtcct cctgaaaatg attaagatat
     1561 attttaccaa attttcagaa aatcacaacc ctttttgcaa aatttttgag attattttca
     1621 caaacttgat ttttcaaagt atactcaata aaaataaaaa aaatccacta cgtcaaggcg
     1681 aggctaatgt ggtttgaaga aattttcgaa gagcgtgaat gagtatcatc tatagtaaaa
     1741 taaaaaaact gaacaatttg gttggggaca gccaaaccaa tttctcacaa tgtttcagaa
     1801 acaagggtgt gctactccaa tttcagccta ctataactgt catagattgc tgaaacaaag
     1861 tctaggtaaa agtcttcata ataaaaagac ctcctatcaa gtgttcaaaa actttgatag
     1921 gaggtcttgt tttgtgaaaa tatttatcaa attttctata caagtgagct gttagccagg
     1981 ttctttctat tctttcaatt tcaatgaatg gattttttac taatactcat aactgggaat
     2041 ttgtctgtgt aaaaatagcg agatagatgg tatttataaa acactcaaga cagctagact
     2101 aatatcattt aaaacattat cttcttttga gcgactgttg gttaccaaca tagctaaatt
     2161 tcctgcattt tcaaattgat agggttctga tttagcattc acaaccacca agaggtgttc
     2221 tttgccgtga acttcataga taaggtagcc gctatgttca atcgcagaat gcacaaagac
     2281 atgatggtaa atttcatcat agctagagta agaaaaggca ccagtttttg tcttcaatcg
     2341 gatgacttga cggataaact caatactgtc ttgacgctca ttaatcaagt tccagttcac
     2401 ttggttcaca ctgtcaggag cattatagct attcatcgca cgctctctat catcatgggt
     2461 caactcacca ttttcaccag tcgcaaccag tttggtacga ccaaattctt gaccgatttc
     2521 cataaaggcc atcccctgca tgagcagatt catggctgtg gcagtttcga ccttgcgcat
     2581 gatttgctct gaactttggt ctggatgaag ggttgccaat aaatcgtgaa gattgtaatt
     2641 gtcatgggct tctacatagt taagcacctg atttggatgt gtatagcttc ctaattcacg
     2701 acttcctagg attgctttag ctagaattgg ctctgtcgca gcaccactga caaaacctga
     2761 cttgatagca ccataaactt ctcccccttt gacagcatcg cgctgattgt cattaaagaa
     2821 accaatattt ggcatctggt aggcattgtc cttcttggcc ttatcataag gggcaagacc
     2881 tgttcccata tcccatcctt ctccatagag gataatgttg gagtcgattt catccaagct
     2941 ttgacgaatc atctgcatgg tcttgacatc atgaatcccc atcaagtcaa aacggaagcc
     3001 gtcaatatta tattcctgca cccagtatag aagagaatca atcatatact tgcgaaacat
     3061 ttcgtgttca ctggctgttt catttccaac acccgttcca ttctggaagg taccatctgg
     3121 attcatacga taatagtaat cagggactgt tgtttggaat ggtgcatcaa caactgagaa
     3181 ggtatggtta tagactacat ccataatgac tccaataccc gcatcgtgat aagcttgaac
     3241 catcaccttc aaatcacgaa tgacctgagc tggatcatct ggattagttg aaaaactagt
     3301 ttctggcgcg ttatagtttt gtggatcata accccagttg taggttacat ttccatcctc
     3361 atcgtattct ttatgacggt ctgcaattgg ttgcaattga acataattgt agcccagctt
     3421 cttgatgtaa tcaaaagcag ttgactggcc gtattggtta actgttccag cctgagcagc
     3481 acccaagaaa gttcctcgaa gatgttcatc tacacccgat gtaggtgatt tagtcaaatc
     3541 acgaatatgc atttcacaga taactgcctt acatggattt tccaagcgcc aagtagcctc
     3601 cgaaccgtgc ttaacctcga agttttcaac ttgcttttct acatggctca gaatagctga
     3661 acgtttgcca tcagggctgg tcgcgattgt ataaggatca cgtgtcagtg tttggtgatg
     3721 agggaattgg acttgatact gataagcctt acctaccaaa tcttcctcaa catccaaact
     3781 ccagacaccg attgtattgt ccttatgatt ataagagtag ctattgcctc ttttcatctc
     3841 aaaagtcttc caaacgggtg catcattagc agctgattca taaacgacaa cttgcacttc
     3901 tgtcgctgta ggtgaccaga gggaaaaatg agcctgattg tcctctacac ggcaacccaa
     3961 ttctccttgg taaccccaat gatggtcaaa actagcactg ttaatggcct tatcaaaggc
     4021 aaaaggattt tgatttttat agaaaggact ggcaatagca ggattttcag agtaataaat
     4081 cctatcatcg ccttccaaaa tccagacctc tgttaatagg ggatagtgat taaaacggat
     4141 agaatattct ttactagttt gacctgtatg aaccacaaaa ttcaagcttt ctataacatg
     4201 tgaacttggg tgttcaaagc taaataaagc tccaaaataa tcttctttgt aggttagcaa
     4261 atcaattcgt tgatcctgac tttttacaaa ggagcaagtg tcatattctc cattcttacg
     4321 atggtaatga atgcgcatag ggtagttata cattttttat ttttcctttt tactttgttt
     4381 ctatttcact aataaatttt tgtcaatctc gtctcaatta acagacatag tcatattctc
     4441 taaactctgt ttttaaacga tccattacaa actttctagc catgcctcat ctctgacctg
     4501 gataccaagt tcttgtgctt tttgcagttt acttccagcg tctgcaccta ccacgacgag
     4561 gtcggtcttt ttagaaatac tacctgtcac tttggcaccc agactttcga gtttactttt
     4621 agcttctgag cgcttgagtc gttccaattt tcctgtcaat accacggtca aacctgacaa
     4681 ggccgcatcc gctactaccg tctgtccttt atagtccaga ttgaccccag tttctttcaa
     4741 ttctctgagc agaatttcag agccttctgt cgcaaaataa gtctgaagac ttttggcaat
     4801 cacgccacct agactttcaa tactagccac ttcctctgaa tctgcctgag acagattttc
     4861 aattgaatgg aaatattgaa gtaaaagctg actaaccttg cttccgacat gacgaattcc
     4921 caaaccaaat aagagcttct cggcagaatt ttcctttgat gcttggatag cctgatacag
     4981 tttagcagcg gacttttcct taaccccctc taaaaggagg aaatcctctt cttgcaaacg
     5041 ataaatatcc gccacatcct tgactaaatt agcagcaaaa agcttctcaa caatagatgg
     5101 accaaggcct gtaatattca tagcatcacg agaagcaaag tgaatcaagc cttccatgat
     5161 ttgagcaggg caacgcggat tgatacaacg tagggccact tcatcttcaa agtgcaacaa
     5221 gtcagagtta caacttggac agtttgtagg gatatctagt ttttcttcag aaacccgttt
     5281 ggactctacc acacgtaaaa cggcagggat gatgtcacca gccttatata caatgaccgt
     5341 atcgtctttt cggatatctt tttcagcaat ataatctaca ttgtgcaggg tcgcacggct
     5401 aacagtcgta ccggcaagtt gtactggtgt tagattagca gttggagtta caacaccggt
     5461 acggccaact gtccagtcaa ctgataagag ttgagcttct ttttcttcgg cagggaactt
     5521 gtaggctact gcccactttg gagccttaac tgtaaaacca agttcttctt gacttgctag
     5581 gtcgttgacc ttgattacca ctccatcaat atcgtaaggc agattttccc gttcctgtcc
     5641 tacttcttgg ataaaattcc agatttcatc tatgttttca gccaagattc gcttaggatt
     5701 gaccacaaaa cctagttgtt ctaggtactt caaacccttt tcttggctat cacgagttga
     5761 agggctggct tcttgataga gaaacgttgc aagattacgc ttggcaacta ctgctgtatc
     5821 caactgacgc agagttcctg ctgccgcatt acgaggatta gcaaattcag gctctccatt
     5881 ttcttggcgc acttggttaa cttggtcaaa ggaagcgcgt ggcatgtaac attccccacg
     5941 aactgtgata tctagttctt ctggcaaagt caaagggatg tccttaacac gcttgaggtt
     6001 ttctgtgata ttttcaccaa ttgaaccatc tccacgtgtt accccagcaa ccaaaatccc
     6061 cttttcataa gtcagcgaga tagataagcc atcgattttc agctcacaaa tataggtcgg
     6121 atgagccact tccttacgaa cacgcgcatc aaaagcatct agctcctcac gtgaaaaagc
     6181 atcctgcaaa ctataaagag gatactgatg actgtatttt tcaaaaccat ctaaaacctt
     6241 gccaccaaca cgatgagtcg gactgtctgc tagcacttgc tctggataag cagtttctaa
     6301 ctcgaccaac tcacggtaaa ggcggtcata ctcactgtct gcaaccgagg gattatcgct
     6361 ggtatagtac tcagtcgcat agcgattgag caaagcgact aactcattca ttcttttatt
     6421 cataagacca ttttaccata aaacaagccc tcctcacaaa cgagaagggc ggaaaaaaca
     6481 cttagtttga aattattttt gaaactcaag caaccttata tcaatttttc aaaatgagtt
     6541 cgaacataaa taaacgatat acaagacaag atgataacac cacttccaat tatcaggaaa
     6601 gaagagagat gtacacttgg caagactgtc ataaatcctt ttgcaatagg cataaataga
     6661 atagctaagg taaaaattgt actcagtact cttccaagaa attcgctctc aaccttggtt
     6721 tgtacttgag taaaaaagtg aatattaaaa atcgtcataa acaattcaca aactaaattt
     6781 ccagaaaagg aaagaaaagt tggaagtggt aatcccatca taaaaactcc gacacctgtc
     6841 aaagccagta aaatcaaaag attataaata ttagctttaa ttttactagc tagaagagcc
     6901 ccaatgatgg aaccaatagc ccccatagtt aaaatacttg cataggctcc ttctgacccg
     6961 taaagctgat tcgaaaaggg aagtagaaat tcaaaagctg caaaaaagaa attaacgctg
     7021 gaagctacca gcaaaaggaa gaaaatttct tgctgatgcc agatatagtg taacccatcc
     7081 ttgatatcta caaaaatatc tctcccagta aaagcctttt tctcttgaac ttttgcttcc
     7141 tcttttggaa ggaaagccac tagaacaaaa gcaatgaaaa aagtcagcga gtctagcagt
     7201 agcgtcatat tgagacttgc aaactgtaaa acaaggaagg aaagaacagg agagctaaca
     7261 cctacaacct gcaaaaccag ctctaagcga gaattataga tcacaatctc atctttctcc
     7321 accacttcag ttatgatagc tttattggct gtgcgagaaa aggcaaaagc aatagcctgc
     7381 acaatgttag caacaatcaa agcgccaatc atccagctat cattccttat gaaagaaata
     7441 gccagacaaa gaatcccaca aacaagatct gccgtcatta aaatcttacg acgagaaaaa
     7501 cggtctgaaa taactccgcc aaagggattg acgagaatag atgtgacgag ctcagaaatc
     7561 tgatacattc ctaaaactgt ctgtcctata gtccccatag aagccaacca gacactattt
     7621 ccataatcat agagcatatt tcccatttta ttgatagccc cacggctaat caactgcact
     7681 gcatagcgat tcatattaaa gctcctctca aattttgaaa ctattgtatc aaaaccgaaa
     7741 ggagcttttt attttttccc ttatttggga aaattaactt ttgacaaatt tttcgtagtg
     7801 ttcctgataa taggctactt gctctggaag acctaacaca tcaaaaatat gcatggcctt
     7861 ttgcatctgc ttacagcctt ctttacactg tcctttttga tataaggcaa aaccttttaa
     7921 ataatggaaa acattacgct cataaagctt aatacctttg tcaataatct tctctgtata
     7981 agcctcaaaa tagttggcat tataaaaaga agaatgctct aaacaatgct ggtaacaatt
     8041 gagggccaaa atcaaaacta atctcttatg gcgactaatc tcttggtaaa attcctccct
     8101 ctccataact tctctaccaa tccgagtgac atagtctaca tcgtagaaac tatagaggtt
     8161 accgaaaaga atcaactcat acatggtcca ttcttctgtt ttgaagagat aatctgctac
     8221 cttatccaaa tcatcctgct tcatatcata agtcgcatct ctttgacaaa tcagaccttg
     8281 tagcaaaatc cagttcagct caaaataaag ggaagtcgtc gaactcttag acttttcaag
     8341 ttgttctctt tgaagctttt gaaaacctgc aatatcgttt gaatagtaaa gtgggataat
     8401 ctgtgccatc atagacacat gttcatgatt atgaaaattc cttgccttat ccatgaaatt
     8461 ttcgattgtt acatgaatgt tatccaaaat ctcaaagaaa cgggagactg ccaggtcaga
     8521 ctccccaagc tcaaagcgag ataactgaga ggtagagcag gattcgcctg ctgcttcctt
     8581 taaagaataa tttccacttg ttcgaaattc acgaaatact tttccaagat gttccatctt
     8641 tacacctgat ctgataattc ttcccactca agcatagctt cttcctgacg atggctgatt
     8701 ttgtccagct cagcctgtaa ttccatgagt ttgtcggcat cgtttgtttc caacatttgt
     8761 tcagaaatgg cttggctttg actttctagc tcttcaattt cagcttctag actttcgatt
     8821 tgtcgcatga gtttgcgaac ttctttttga ctttctttct gggcctgata gtcattgact
     8881 ggacttgctt cctttgcttg attgctagtt gaagcttcct cagtctgact catttctgct
     8941 gttgctttct tctcaacata gtagtcgtaa tctccaaggt agagagttga accattctca
     9001 gacaattcca aaacatgagt tgccacacga ttgataaagt aacgatcatg actgacaaaa
     9061 agcaaggtac catcaaagtc aatcaaggca ttttctagca cttccttact atcaatatcc
     9121 aagtggttgg tcggctcatc cagaatcaaa aagttattgt tttccataga caatttagct
     9181 aaaagcaaac gagctttttc gccaccagat agcatgccga ctgatttttt aacatcatct
     9241 cctgagaaaa ggaaggcccc aagacggttg cggatttcaa cttctggtgt cagtttgaaa
     9301 tcattccaga gttcatccag caccgtatta cttggtgtca gcttgctttg ggtttggtca
     9361 tagtaaccaa cctcaacatt agcgccaaag cgcttttcac ctttgataaa aggaatctgg
     9421 tccacaatag acttgataaa ggttgacttg ccgataccat ttggaccaac gatagcgaca
     9481 gcattcatct tacgaagatc taggttgata ggttgtgaca aaacttcccc gtcataacca
     9541 atagcagtat tttcaacagt caaaacaaca ttgcccgacg ttttttcaga ctggaaggtc
     9601 atgttggctg ctttcttgcc agcttcaggc ttgtccaaac gctccatttt ttctagttgt
     9661 ttacggcgag attgagcacg tttggtcgtt gaagcacgaa ctagattgcg attgacaaag
     9721 tcttccagag cagcgatttc cttctgttgc ttttcatagt tttttgcctc agtagctagc
     9781 ttttgctcct tcaactcaac aaaacgagag taattcccca catagcgatc caaggaatac
     9841 ttggtcaaat ctagcgtaat tgtcgcaacc ttgtccaaga aataacggtc gtggctgacg
     9901 ataatgaggg caccgctata gtttaccaag taattctcta gccaggagat ggtttcaata
     9961 tccaagtggt tagttggctc gtccaagacc aagagattgg gcttttcaag gagcatttta
    10021 gctagagcca aacgagtatt ttgaccacca gaaagctcag caattttcat ctgccacata
    10081 gactcgtcaa acttgaatcc attcaaaatc gctcgaatat cagcttcata ggtaaagcca
    10141 cctgcttggc gaaaattttc agataagcgg tcataatctg acagcagttt atccaaatcc
    10201 tcaccagact tttcacccat ctccagctcc atctgacgca gttgtttatc tgtccgacgt
    10261 aagtcatcaa agacatgaag catctcatca tagatggtat tttcagactc aaaacggcta
    10321 tcttgagcta ggtaagacag agaaatatct tttttcttat tgatttctcc actagttggc
    10381 tcctcttctc caactaaaat cttcaaaaga gtagacttac ctgcaccatt tttcccaaca
    10441 agggcaatcc gatctcgttc atcaacctgc aggttgatat tatcgaaaag aacctctcct
    10501 gcaaaagaac gttcaatttt attagcttgt aaaataatca tacaagtagt atagcatgtt
    10561 tccctaaggc attcaagata atcgtaagtc ttttagtaca acttttataa cataaaataa
    10621 actaaattat gtatatttta tattagattc cttcactatc ttgttggatt ttctaaccag
    10681 ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt taattctttt cattatttac
    10741 gtacgcgtat agcagattga aataagatga gaacaaatcg attgggaaag taaaattaat
    10801 ttctataaat gttttagcaa ttgtttcgta ctattttaga ttcagtctac tataacacat
    10861 tcagaaaaga gaaaaagtct gttgattttg accatcataa aaagactggc aatccagtct
    10921 caaacatata ttatagaaat tctccactaa atactttcac gaatattcag aagcataaca
    10981 aaggcaacta gaagaaatag caataaaaca aagctaactg ccagagttcc aaagctagta
    11041 gcaatggtta ccaaagatat tgtaaataag ctaggtaaaa caaccgtaat ggcactgata
    11101 gaagattgaa ctgctcccat tgactcctca ggtatttgtt taaagacgag ttcttgcaat
    11161 ctaggagaga gaacacctgc gaaaaaggca tccaaggtac taaagatgag aatccagtca
    11221 aaacgaactg tggcaaatcc tactagaaga agcaactgga tgacaagtga ggcatagaga
    11281 gctgttttta tggaaatggt atgttgcaga tagccactta caaggcttcc gacaatcagg
    11341 gctgacagtt caaaagtgga tagcaaggca agagattgac ctgtttgtaa attcaaaaag
    11401 ggttgattcc tcaaaaatag agtagagaca ggaactgtaa catttatcac tgcttgacta
    11461 gtagagataa taaacaaaac caagagcacc ttattcatat tccatatcaa tttcgatgat
    11521 tggagcaaat gctggcaaaa ggattttaca gagagtcctt cttgatagct aatcgttttt
    11581 tctactttca agaggtcagt ttttatgaag aggataccta aaaatgcgat taaaaaggta
    11641 agagcgttca gtaaggaaat aaactggatg gatagaatac ctagtaagac tcctcctagg
    11701 atattactga ttgttttcac taaactaaca gttgactgtt taaatccaat agcttctgcc
    11761 agatgatctt gcccaataat tctaatgaaa atcggagtga gcatggcgcc tgaaaaataa
    11821 ctcaatgtgt cagacaagag gttaatcata caaataaagg ttactagcaa caaggaaaaa
    11881 gactgccctg aaagcgatag ggacactata gagtaaagca aaaattttgt aaaactaatg
    11941 actgtgtatt tcaagacacg atgatgttga aaatccgcca aaactcccag aaagatttgt
    12001 agaacttggg gaagggtttc tgaaatcgtg ataagtaaaa tcgccaaagg ggcaaaagac
    12061 gcatctgcca cataattcag gaaggccaga taaaaaatcg tatccccaag cgttgaaatc
    12121 cactggttga tagttaattg cctaaaatct ctattttgaa gaaatacttt cattacaact
    12181 ccttcttaag ttcaaatggg aatctttccc caagaataga ccgcgatact actaacaacc
    12241 aaaattacag taacatcaaa agctgaccaa taccattgta gactatatgc agtccaatag
    12301 gccaataaat tgactttgtc attctaaata agactgcaaa tataagacct ccacccatat
    12361 agaagacaaa gtctgtcaag acccaaccgt gattactaat gtgcgagacc ccaaataaaa
    12421 tagcagagcc aagtacatct agcccccatt tctttccttt ttccagagct gtcatcacca
    12481 atccccgatg gattatctct tcaaaaatgg gacctgcaat cacaggatag aaaaaataca
    12541 tcaaaaatgc tgtagcccct gtaaaagtcg gagcagcatg ttgataagaa atttcatttc
    12601 gagtaggtgg gaaaagaaaa aaggtaacga aattccaaac aacaaaagca agcagagcta
    12661 ggaaggaata gaaaagatag gatcctttaa actttctact attgattttc tgccatttcc
    12721 ccgaccaaat catagcaata agagcaaata aaaccacaag aaaattcaac atcatatccg
    12781 acagataata ggcaaagtca gatagcccag taacaaggtc gctgcgtaaa actagaacac
    12841 tgaacttctg gtcagcaata actagtagaa aaactataat aaagtagcgg tgtgagatta
    12901 tctttttcat tctatttcct cctatactat gaaataaaga cagcccctac ccaagaaaag
    12961 gcaagggctt tggatattaa taacgacggc ggtcagaatc aaagtcaggt ctatcgttaa
    13021 aatttttctt ccagaaatta gtgattgacc aaggtgtccc gaaccctccc caagcaccgg
    13081 ctgggataac agcattattc ccaaattccc ctccataaac tatctccaac tcagcttctg
    13141 tcaattccat tgtttctgca aattgtaaat ttaacatctt ttacactcct tcaattatct
    13201 tcatttgtaa accacttctg cgacctagga tttgcttcaa gtgctttaca agtacagtat
    13261 aacacgaaaa ttggcttatt ttagaaaatc gcatatttga tattttttct tatagaaatt
    13321 tcagatttgc gattttggtg aatttgatta cttctctggt ataataaagt tactactaat
    13381 gaggagtgga gaaatatgaa gaaacaaatt ttaacattat tgaaaatcgt tgctgagatt
    13441 attattattt tgccatttct aactaatcga taagcttttt gtattgctgc aaacgcaatt
    13501 caaaaagggc tattaattgt ggattttcta atacttgcag agattggata aagtgttcaa
    13561 tctctttttg attgcttccc ttagtttgaa ggaaaatgct catcttcttt aaaaactgcc
    13621 acaacacttt ctcaaaaaca tcgtatggac ggagcatact ctccagctcg gcttcaaaga
    13681 ttgggatata agaaaaaagt ttgcgctcca tgagctctga gatgatattt aagagtcctt
    13741 gcttcatata caatcgattg tgtactaact ctttaaattc tttggatttt tcgagtaagg
    13801 aggttgataa aaagatcaga tcttgattgc tcaagaaggg cagagtattg caaaagagat
    13861 agagttcaaa ccaggtccaa gactcgatag catagagata ggtggtcaaa aactcgctat
    13921 cctcctctgc tagtgggtag cttttatcta gtgagtggat ggcatctttg attacaatag
    13981 cattcaaacg acgataagtc tctgccatct gttcttgctc gacttcctcc aacagttgct
    14041 ctaagccagc tatatcttga tgagcaaagc gatccacaac ctttctacca atctgcatat
    14101 gtggagattc ttgatagttg ttgagcttgt gcccaaactc atcaaaggtc acattgatcc
    14161 cttggatggc taatatgagc ttatcagcag acaacatgga ctgccctagc tcaaacttgg
    14221 acaactgaga agctgttagc ccgtcacaag ccacatctga ctgcttgagc tttctcgcca
    14281 aacgtaattc cttgtaaaat tcccccaatt ccattttttc aatcatccta ccacctccta
    14341 gcttttgcat attatatcat tatttgtgtt catttgtcaa aatattctga tagttagaaa
    14401 aaataaaaaa gccagcctta agctgactct aaaaggaccg agccttgtac aatacagaac
    14461 tcaatcctcg ttctaaatag aatgtctaac ttttttgggc agtacacgag cttggggaac
    14521 agccactgga acgatgaggt gtgagctcaa aatatcctcc agttatgttt ttcctaatag
    14581 tataccggaa gagtgaaagg attttataat ggagcggtta caaagaacct actttctatt
    14641 aaacagtata ctatgaaaat gtgaaaattt aacatttttt tgtacaaatt ttataaatta
    14701 ttgccttttt aatatcaata gttaatctct tatccagatc ccccttgtgt aaactttatc
    14761 tttataagct tcaaggcccc tatcccatct atttgcaaca attagatcac tttgttttgt
    14821 aaatagttca aaattctttt caaaaattac gttatctata ctaacgttta aatttggttc
    14881 atatactaaa atttttatac cgacaatcaa tagttcatta attatactta aaatagctga
    14941 ctctttgtaa ttatctgaat tatatttcat ccccaattta tatattccta ctatctttgg
    15001 ctttcgttcc aatatttgtt taactatgaa ctgttttcta tttgtgtttg aaatatcaat
    15061 cgcttctatc actggggcat ttatttctat aaattctttt tttaattgtt tagtatcttt
    15121 gggaagacaa tatcctccaa atccaaaaga aagattatta taaaaatttc caattcttgg
    15181 atctaaacaa acacctttta ttacaacttc agcatttaaa cttctcctct cagcaaaaga
    15241 atctagttca ttaaaaaaag caacacggag agctaagaat gtgttagaaa aaagcttaat
    15301 tgcttctgct tcagtaggag aaactaacat aacattttta atattggcag tactatgagt
    15361 actaatcgaa aggaacaact ctgcaatttt tcttccttca actgtctcat ctccaacaac
    15421 tatgcgactt ggatataaat tatcatatat agaacaacct tctctcaaaa attcagggac
    15481 aaaaatgata ttttttgtat caaacagcct ttttaatttg tttgaaaagc cgaacggaac
    15541 tgttgacttt aaaataatct ttccattagg ttttaccctc agaatcttcg ataccgtttg
    15601 ttcgatttca tatgtattaa aactaccaat tttctcatca taatctgtcg g
//
LOCUS       DBEJJV010000044        15603 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.044, whole genome shotgun sequence.
ACCESSION   DBEJJV010000044 DBEJJV010000000
VERSION     DBEJJV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.044"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..1000)
                     /locus_tag="ACL3GT_001726"
     CDS             complement(<1..1000)
                     /locus_tag="ACL3GT_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HGR0517355.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNI"
     gene            complement(1010..1963)
                     /locus_tag="ACL3GT_001727"
     CDS             complement(1010..1963)
                     /locus_tag="ACL3GT_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HGR0517356.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMSDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            complement(1956..2480)
                     /locus_tag="ACL3GT_001728"
     CDS             complement(1956..2480)
                     /locus_tag="ACL3GT_001728"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0517357.1"
                     /translation="MDPEKRPDRFLEFAEKLFLVREDVIFIMAGNGSMWAALKEKICH
                     LKCRDNFRLLGEIYPATIVYQISDLLYIPSDTEGIPMCVLESMSQGTPVLASNVGGLS
                     EIIEHRVDGFLFEKEDVEGVCACANFLLNDSEYLKYIGENSKSKIRKHFSVQKMFVET
                     MRVYDELLEKSSHG"
     gene            complement(2608..3162)
                     /locus_tag="ACL3GT_001729"
     CDS             complement(2608..3162)
                     /locus_tag="ACL3GT_001729"
                     /inference="COORDINATES: protein motif:HMM:NF024831.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HGR0517358.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKIQLIHCHGYSTNYFLYMLKKLDKNGFGKVKTVITCHGWVEYNLKKKFLTYFDFWT
                     YSMGDAFICVSETMKKRLESIIKK"
     gene            3405..4096
                     /locus_tag="ACL3GT_001730"
                     /pseudo
     CDS             3405..4096
                     /locus_tag="ACL3GT_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4432..5738
                     /locus_tag="ACL3GT_001731"
                     /pseudo
     CDS             4432..5738
                     /locus_tag="ACL3GT_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(5778..6788)
                     /gene="tsaD"
                     /locus_tag="ACL3GT_001732"
     CDS             complement(5778..6788)
                     /gene="tsaD"
                     /locus_tag="ACL3GT_001732"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HGR0517359.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(6778..7215)
                     /gene="rimI"
                     /locus_tag="ACL3GT_001733"
     CDS             complement(6778..7215)
                     /gene="rimI"
                     /locus_tag="ACL3GT_001733"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HGR0517360.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYVLAYDGAEVIGFLAVQENIFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(7212..7895)
                     /gene="tsaB"
                     /locus_tag="ACL3GT_001734"
     CDS             complement(7212..7895)
                     /gene="tsaB"
                     /locus_tag="ACL3GT_001734"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HGR0517361.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8073..8258
                     /gene="cibA"
                     /locus_tag="ACL3GT_001735"
     CDS             8073..8258
                     /gene="cibA"
                     /locus_tag="ACL3GT_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HGR0517362.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            8260..8412
                     /gene="cibB"
                     /locus_tag="ACL3GT_001736"
     CDS             8260..8412
                     /gene="cibB"
                     /locus_tag="ACL3GT_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HGR0517363.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(8735..8950)
                     /locus_tag="ACL3GT_001737"
     CDS             complement(8735..8950)
                     /locus_tag="ACL3GT_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517364.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            9230..9463
                     /locus_tag="ACL3GT_001738"
     CDS             9230..9463
                     /locus_tag="ACL3GT_001738"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002947111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase subunit epsilon"
                     /protein_id="HGR0517365.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            9465..11144
                     /locus_tag="ACL3GT_001739"
     CDS             9465..11144
                     /locus_tag="ACL3GT_001739"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HGR0517366.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            11216..11365
                     /locus_tag="ACL3GT_001740"
     CDS             11216..11365
                     /locus_tag="ACL3GT_001740"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517367.1"
                     /translation="MKIKEQTRKLAVGCSKHCFEVVDRTDEVSSHTYGKATLTRFEEI
                     FEEYQ"
     gene            complement(11497..13410)
                     /gene="mnmG"
                     /locus_tag="ACL3GT_001741"
     CDS             complement(11497..13410)
                     /gene="mnmG"
                     /locus_tag="ACL3GT_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HGR0517368.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(13420..13875)
                     /locus_tag="ACL3GT_001742"
     CDS             complement(13420..13875)
                     /locus_tag="ACL3GT_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HGR0517369.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQYGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(14016..15137)
                     /gene="mnmA"
                     /locus_tag="ACL3GT_001743"
     CDS             complement(14016..15137)
                     /gene="mnmA"
                     /locus_tag="ACL3GT_001743"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HGR0517370.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
BASE COUNT         4626 a         3481 c         2836 g         4660 t
ORIGIN      
        1 aaatattttt tgcttcatat aacggaaaat ctctattcac ctcatttggt tcgatatcat
       61 tcattttatt tgactcaatt ggattaattg aatacaattt taaaaaaata ggcttcgtac
      121 caataataga ggataattga cctcctaatt cacctagcgc tgtaaaaata acacctgtta
      181 gtgctcctat tgcttcaata gtaccaattt tcactattcc ttttattgca agatagcctg
      241 ttaaaaaaac gagagatatc tgaaaaaaaa tattgagaaa gaagctaata gcgcctgcta
      301 acgtttctac agttgtcttt ctttgtataa ccatctttaa taaaattcct gcttctttaa
      361 ttttcttagg caatacatat aaaagattca aggatgctaa cacatcaaat ccattcaata
      421 tagtctcact agattttaaa aaagcttcat tttggttagt taaatttaga ctaacttctc
      481 gcattttcga tgcaaagatt tttggtacaa gtagcataat cattaatgaa aacaaggtgg
      541 ctacagtcaa tgaccaatga tagtgattaa gagtcacaac tgcaaatata gtaccagaaa
      601 ttccttttat tactaaaaaa agttgtttaa aagcctgatc atttaaagtc tgaacatcat
      661 tatttagcca cgaaagatat gttcctgatg atttactatg aaattcttga taggtagagt
      721 tagagatgtc tgtggcaact ctatttcgaa tctctagatt aaactcttgg atcacttcaa
      781 cctgataatt tttcactacc cagtcaagga atattatccc acaccagaca atcatttggt
      841 agattgacaa tttcaaaaac cgctctaaat tcatcgcaat taattcattc aacaccagag
      901 cattaatagt tgctgcataa attagcaata attgaccagc aacaataaat atcgttaata
      961 aactaaattt ttttatattt gattttataa tagtatacac aatagtttct cactttctaa
     1021 attttaattg aacatagttg tcatatatac aatagaaaaa accaaaatga tataataaca
     1081 tatatttcaa aaaaagaaat tcgttaaaaa ttttttcttc tcttgccttc ttgattactt
     1141 ttaaagcctt gcatttgtct cctattaata gtaaccgctt tatgtttaaa gaataatatt
     1201 tctttgtaac caatattctc tcgttgaaac tcaataaatt aaaatatttc ctacagtaat
     1261 tataatattc ttcatctgca ttaattgttt tttgtgtcac tccagtgata ccgttttctt
     1321 tactgtgagc gtagtaattc accaagaatt ctcgcactat atcaatttgg tatccttgag
     1381 caagtagttt taataaaaca acaccgtcct gatgtgaatc tattttctca aaaccattaa
     1441 ttaattctag cacctctttt ttacacaacc aaaatgacgt acctgctata ttgtgaacca
     1501 tttgaacaaa caagggattt ccaacaaaat cggtcttctc ctcttctcgt gtaccatttg
     1561 gataaattat tattccataa ctataaacta aagctaaatt cttcattcta ctctttttaa
     1621 aacaagccat caactttaaa attcgatctg acatatattc atcatcatcg tctaaaaatg
     1681 atatatactt acctctagaa tttttgatac ctatgtttct ggcattagtt gcacctaaat
     1741 cttcattact taaaattaac ttaattctat gattggtata gccaaattga tggataattt
     1801 tatttcttaa atttacatta ctataattat catcaataat tataacttcg atatttttat
     1861 aactttgatg taaacaactt ttcacagctc taatcagaga ttcataccta ttatgtgttg
     1921 gtattataat acttactaat tcttgatcta tattcctatc catgactact cttctctaat
     1981 aattcatcat atactctcat ggtttctaca aacatttttt gcacagaaaa atgttttctt
     2041 atttttgatt tactattctc acctatatat ttcaaatact cagaatcatt gagtaaaaaa
     2101 ttagcacaag cacacactcc ctcaacatct tccttctcaa ataaaaatcc atcaacccta
     2161 tgttcaataa tttcacttaa cccgccaaca ttactagcta aaaccggagt tccttgtgac
     2221 attgactcta aaacacacat aggtattcct tctgtatcag aaggaatata caataaatcc
     2281 gatatttggt aaactatagt agctggatag atttcaccaa gtaacctgaa attatctcta
     2341 catttcaaat ggcaaatttt ttctttcaaa gcagcccaca tactaccatt tccagccata
     2401 ataaaaatca catcttctct gactaaaaat aatttttctg caaattcaag gaatctatcc
     2461 ggcctttttt ctggatccaa ccttccaaca taacaaatga tttttttgtt atttggaata
     2521 caaaattctt ttttaaagtc ttgaacacct actacatcta aatcgctatt tgatacatta
     2581 attccgttat ttattacaac tatcttctta tttttttatt atactctcca atcttttttt
     2641 catagtttca gatacacaaa taaaagcatc tcccatagaa tatgtccaaa aatcaaaata
     2701 agtcaagaat ttctttttta agttatattc aacccatcca tggcatgtta tcactgtctt
     2761 aacctttcca aatccattct tgtcaagttt ttttaacata tataaaaaat aattagttga
     2821 gtagccatga cagtgtataa gttggatttt taataatttt aaaatatttt taacgtgtaa
     2881 ggcagtttca aaattatttg aacattgagt acaatcaaca taggcaatat ctaaattttt
     2941 ataatcatca ataacctttg aatctctaga tacgattatc aaaataggat atagagacat
     3001 ccttctgatc tgctttttac aaagtccaat tatatgcgga tctatacctc cacaatgtcc
     3061 attattatac ctaactataa tatgagccga aaacactata tccttaatgt ctccatatcc
     3121 atcagggata ttaatattta tttttccaca actatattgc attgtaacca tctccttaaa
     3181 cgacgcatta tgatatttga tagagaaatt tttatgaata actcaataat tttatagtaa
     3241 atcatgctta tatctcaaag atacctattt tctcttgtct cgaccttctc caaagaattg
     3301 ctataatact attacaaata catctgcact acacttcaaa ttttagcact gtataaaaac
     3361 gtttcaacac actaacttta agaaaacttc cactattaat tgaaaaagtt gatagagata
     3421 aattaaagat ctatattgaa actcatcccg atgcttattt gactgaaata gctgctgaat
     3481 tcaactgtcc tccaacaact attcattacg ctctaaaggc tatgggatat agtctaaaaa
     3541 agagctgtac ctactgcgaa caagacccag aaaaagtaaa tcggttcctt aaagaattga
     3601 atcacttaag ctacctgact cctatttata tttatgagac aggggttgag acctattttt
     3661 atctcgaata tgatcgagcc ttgagcaggc agttagtctc tctggaagaa gatataatta
     3721 tttgaattaa gatcgagaca acgcacacca gagattgcga tactgttata gaagtactaa
     3781 tgcccttttt tgtttcaata tactatggct ccgatgacct ataaagatac gatgacgagt
     3841 gactttttcg aagcttgctt ccaaaaattc ttactaccta ctttagatac accatccctt
     3901 atcattatgg acaatgcaag gtttcacaga atgaacatgt gtaaggagca gggcatagac
     3961 tgttaccact tcctacctat tcacccgagt ataatcccat tgagaaaata tgggcttaca
     4021 tcaaaaacat ctcagaataa tattgtcaaa ttacgatgct tttcttgagg cacttttgtc
     4081 ctattcttgt ttcagccgac tatactccgt tattgggcag ctacggaaca gtcgatggga
     4141 cgatgggggg acataaaaaa atcctccagt tttgtttttt ataacagtat actggagaat
     4201 tgacaatctc ggtagatacc tcgttatagc gcggttactt attaggcagt tacaaaacaa
     4261 ctgtgaacag aaaacattcc agagtcagac aagactttgg aatgttttgg ctctataatt
     4321 tctgtagtgg gtaatcccac cccaggaatt atagggtcgt ttcttgtaga aaaaaagccc
     4381 catatgacct ataatgaaaa gcgtctaacc aactcattag aaagggttca tatggaacaa
     4441 cttaagaata ccacagattt gctcggattg aaagacaaaa atatcaaaat cttgtctgtt
     4501 ctgaaatacc aaacccatct agtcgttcag gcaaagttgg attcccccgc tcctccttgt
     4561 cctcattgtc aagggaagat gatcaaatac gacttccaga aagcctctaa aattccgctt
     4621 ctcgactgtc agggtttacc cacggtacta catctcaaaa agcgccgctt tcagtgcaag
     4681 aattgcctta aggtggtcgt ttctcaaaca tccattgtca agaaaaattg ccagatttcc
     4741 aacatggtga gacaaaaaat cgctcagctc ctccttgaaa agcagtctat gactgagatt
     4801 gcccacagat tggcggtctc aacttccacc gtcatccgaa aactgaggga atttaagttt
     4861 gaaaccgatt ggaccaagtt gccaaaagtt atgagttggg atgagtatag cttcaaaaag
     4921 agcaaaatga gcttcattgc ccaagatttt gagtccaaat ccatcctcgc aattttagac
     4981 gggcgaactc atgcggtgat tcgaaaccat ttccaacgct atcagagaga ggttcgggag
     5041 ctggtcgagg tcatcaccat ggacatgtac agcccttatt atcggctcgc taagcaactc
     5101 tttccaaagg cgaagattgt tcttgaccgc ttccacattg tccaacatct gagccgagct
     5161 atgaaccgag tacgaatcca aatcatgaac caatttgacc gaaaatcctt ggagtatcgg
     5221 gcgctcaagc gcttttggaa ccctcgcttt ttcgtttcta ggctcgggct aaatcagtcc
     5281 actggactga tttactacac caggatagct tcaagctctg tcagaaacga ttctatcagc
     5341 ccacgtttcg aatgcactta acccatcggg aagtacgaga taagctgctt tcttactctg
     5401 agggattaca ggttcactac gaactctatc aactcctgct ctttcatttt caagagaaga
     5461 atgccgacca tttctttgga ttgattgagc aagaactgcc aacggttcat ccgctttttc
     5521 aaacggtctt ttggactttt ttaagggata gagataagat tatcaacgca cttaagctgc
     5581 cttattccaa cgctaaactt gaagcgacca ataatttgat taaggttatc aagcgcaaag
     5641 cctttggttt ccggaacttt aacaatttta aaaaacggat tttgatgact ttgaacatca
     5701 aaaaagagag tacgaatttc gtactctcca gattgtagct tttcgcctac ccactacact
     5761 tgacaaagag ccactcttta ttccatggta tcaaaggcaa gacttggttt ggcattgagg
     5821 tcccagcctg cgaagttttc tttgttccac tcgctgacgc tggcataggc aatcatacct
     5881 gcattgtctc cgcagagtcg cagagggggg atgataacct tgacatctgt gatttcggct
     5941 gctaggcgtt ctctgagacc tttattggct gccacaccac ctgccacaac tagggtttta
     6001 acaggatatt tctccaaagc cttcttggtt tttgccatga gaatgtccat aactgctgct
     6061 tggaaggaag cacacaaatc ttctgtagac aggctttctc ccttttgctc ggcattgtga
     6121 tgaagattga taaaggcaga tttcaaacct gagaaggaga actccagatt atcttcctta
     6181 atcatggcac gggggaaatc ataaatatcc tgcccctgat gagccagctc gtcaatctca
     6241 cgacctgcag gataggtcaa gcccatgaca cgaccgacct tgtcataagc ctccccaact
     6301 gcatcgtctc gtgtctcccc aacaatcttg taatctcctg cctccgaaac atagaccaac
     6361 tctgtgtgcc caccgctaac caagagggct agcaagggaa actccaaagg ctccacactc
     6421 tgagctgcca tgaggtgccc agccatgtga ttaacaggaa tcagtggaag tccgtgagcc
     6481 caagcaaagg ccttggcagc tgacaaacca actagcaagg ctccgaccaa gcctggtccg
     6541 taggtaaccg caacagctgt cacgtcctct tcggtaatcc ctgcttctgc caatgcctcc
     6601 tcgatacagg ctgtaatgac ctcgacatgg tgacgactgg ctacttcggg cactacgcca
     6661 ccaaaacgtt tgtgactctc aatttgacta gcaatgacat tggacaagag ctcatcgtcg
     6721 tttttcaaga cggcgacact ggtctcatca caggatgtct caaatgctaa aatatatcta
     6781 tccttcatct atttctctct tcatgataat ggcgtcctcg actgggtcat ggtagtaggc
     6841 ctttcgctca gcgatgaccg ccattttttc tttcttgtaa aatgcttgcg ctcgttgatt
     6901 tgactttctg acttcgagga aaatctcctt atctgtcggc aattgagcaa acaaggctga
     6961 cgcaattccc tgaccctgat aagctccttt aacagcgatt tgcaagactt ctgcctcaaa
     7021 gatattttcc tgaacagcta gaaaaccaat cacttctgcc ccatcataag ccagaacata
     7081 ccaagtctgg tcttgggaca ggtctgcttg gatttgctcc agagtccaag gactgactag
     7141 gtaaacagct gccataacag cgtagatggc ttgagctagg tcaggctgtt gttgaattcg
     7201 cttgatttct atcataggcg tttaatgtag gactcaccag actcggtatg gttcttgagc
     7261 cagttttcct cagcctcgac tcgtttgagg taattcggca caaaatcatg caaggagtct
     7321 gcttccttgt cccaagctaa aagagcaaga ttggctgcat tgggcaatgt ttctttgtaa
     7381 tcagtccttg gcaagtgttt ttgaatctgc tcaacaaagg ggccaacttc tccgacaaag
     7441 gttacctgac tagtaccctt gactttttct agcacctctt caaaagatag gtgcgcttct
     7501 gccatgacag gtttggcatt ttcataaaat cctgcataaa cattattgcg acgcgcatcc
     7561 atcaagggga caaacaaacc ttcttgttgg tggggcacca gagccaagag actcgacata
     7621 ccaaccaact cgatgttcag ggtgtaagct aaggtcttag cagttgctac cgcaattcgc
     7681 aagcctgtat agctacccgg cccttcagct accacgattc ggtccaaatc cttgggtgtc
     7741 caatccaaac ttgccatcaa aaaatcgatg gcaggcataa gagtaatact gtgatttttc
     7801 ttaatattaa tcgtcgtctc ggcaagaacc tgcttatcct ctaaaatagc cagagaaaga
     7861 gccttgctgg acgtatcaaa agctaatact ttcataacac attcctatct ttttgtctgc
     7921 ttactattat actacaaaag ctggcacatg ggaattttct ttgcccccag acaagagtgc
     7981 cctcacttaa ctaaaaataa tttaaaaaaa tgctcacttt tccttttctt ttccgaatat
     8041 aaaagtgaac aagaaaaaag gaggaaagtt caatgacaaa ttttgacatt cttgacaatc
     8101 aatttttatc cttatctgaa aatgaattat cagatattga tggcggtctc gctcccttgg
     8161 ttatctttgg agtagcagta tcttggaagg ctattgcagg tggaacagca cttataggtt
     8221 ctggtttggc agctggttat tttttaggag gagattaata tgatgaaaga tttgaacaat
     8281 tatcgtgaaa tttctaataa ggaattgcaa gaaatcaagg gtggctttgg tgtcggtgtt
     8341 ggtatcgctt tatttatggc aggttatacc attggaaaag accttcgtaa aaagtttggt
     8401 aagtcatgct agataagaaa cacattttta gaaggataaa ttttattgtc ttcatctctt
     8461 acagtttgct cagcattctc aatgatttga acattactac catcccttta ccattcgatt
     8521 tatctgtttg tattgtttta tttttatgct tcaactctat ttttgatcag aacaatgact
     8581 cccataaaaa taataagctt tgaaaattcc attgtcatgt catgttagaa aaatgcaaag
     8641 accacctcat cttgatagat ggggtggaat tttcgtgtcg taaatctact atctctacat
     8701 ccccaaacaa aaaaccccag cataagcagg gcatctaagc atttaattca aagtaaaata
     8761 caaaccaaac gacataggtc acgaggagga gaaaaagcga gtagagagtc acaaaggtca
     8821 ttttccacaa gaacttggtt tgtcgtcgtt ccagtttggc aaatagaaga ttccccgcat
     8881 aaacgcaagc aacaaaaaca ataaaagcta ccaagcgagc tccgatagca aaagcaaata
     8941 agttatacat agggcaacct ccttgactta aaatctatat ggaattatga caagcaataa
     9001 atttcacttc cgttatcaac ataatacatt ttctttattc ttgcaaacgc ttaccaaaga
     9061 aatcgtcccc taactttctc gtttccgtct tttactaatt tttcattttg tggtataatt
     9121 gaaataattg taacgaatca aggtcaatct agacacaaaa tggaatgaaa tcaagcaaat
     9181 atctgctaaa agtttggaat aagctgacct gtaaatagaa aggaactata tgatttacaa
     9241 agttttttat caagaaacaa aagaacgtag cccacgccgt gaaacaacac gcgcacttta
     9301 cctagacatc gatgccagct cagaacttga gggtcgcatc actgctcgcc aacttgtcga
     9361 agaaaatcgc ccagagtaca atatcgaata tatcgaactc ttgtctgaca aattgctcga
     9421 ttacgaaaaa gaaactggcg ccttcgaaat cacggagttc taatatggcc tatactctta
     9481 aacctgaaga agtcggcgtt tttgccatcg gtggtctggg agaaatcggg aaaaacactt
     9541 acggaattga ataccaagac gagattatca tcgtcgatgc tgggattaaa ttcccagaag
     9601 atgacttgct tggtatcgac tatgtcattc ctgactactc ttacatcgtg gacaatatcg
     9661 accgcgtcaa ggctgtttta atcacacacg gacacgagga ccacattggt gggattccgt
     9721 tcctactcaa gcaagcaaat gtccctatct acgctggacc gcttgccttg gctttgatcc
     9781 gtgggaaact cgaagaacac ggcctcttgc gcaacgccaa actttacgaa atcaaccaca
     9841 acaccgagtt gacctttaaa aatctcaagg caactttctt tagaacgact cactctattc
     9901 cagagccttt ggggattgtc attcatactc ctcaagggaa aatcgtctgt acgggtgact
     9961 ttaagttcga ctttactcca gttggagaac ctgcggactt gcatcgtatg gctgcgcttg
    10021 gtgaagaagg cgtgctctgt ctcctgtctg actcgacaaa tgcggaagta ccaaccttta
    10081 ccaactctga aaaagtcgtt ggtcagtcca ttatgaagat tatccaaggt attgaaggac
    10141 gtatcatctt tgcatccttt gcctcaaata tcttccgtct ccagcaggca acagaagctg
    10201 ctgttaagac tggacgcaag attgcggtct ttggtcgttc tatggaaaag gccattgtca
    10261 acggaatcga tcttggctac atcaaagctc ctaagggaac ctttatcgag ccaaatgaaa
    10321 tcaaagatta tcctgcagga gaagttctta tcctctgtac aggtagtcag ggtgagccta
    10381 tggcagctct ctctcgtatc gccaacggaa cccaccgtca agtacaatta caaccaggtg
    10441 ataccgttat cttctcttct agtcccatcc ctggaaacac tactagcgtc aacaagctga
    10501 ttaacatcat ttctgaagct ggtgtcgaag ttatccacgg taaagtgaac aatatccata
    10561 catctggaca cggtggtcag caagagcaaa aactcatgct ctgcttgatt aagccaaaat
    10621 acttcatgcc tgtccacggt gaataccgca tgcaaaaagt ccacgctgga ctagcagtgg
    10681 atactggtgt tgagaaggac aatatcttta tcatgagcaa tggcgatgtg cttgccctta
    10741 ctgctgactc agctcgtatc gcaggtcatt tcaacgccca agatatctat gtcgatggaa
    10801 atcgtatcgg tgaaattggc gcagctgtcc tcaaagatcg tcgcgatcta tctgaagacg
    10861 gtgtcgttct ggcagtcgca actgttgact tcaaatcgca gatgattctg tctggtccag
    10921 acatcctcag ccgaggcttt gtctacatga gagagtctgg cgacttgatt cgccaaagcc
    10981 agcgtatcct cttcaatgcc attcgtatcg cactgaaaaa taaggatgcc agcgtgcaat
    11041 ctgtcaatgg tgccattgtc aacgctattc gccccttcct ctatgaaaat accgaacgtg
    11101 aaccgatcat catcccgatg atcctcacac cagatgaaga ataaagcaag aaaacagccc
    11161 cgtcctcgga gctgtttttc tctatgcttt cttttgagat taaaactcat actcaatgaa
    11221 aatcaaagag caaactagga agctagccgt aggttgctca aagcactgct ttgaggttgt
    11281 agatagaact gacgaagtca gtagccatac ctacggcaag gcgacgttga cgcggtttga
    11341 agagattttc gaagagtatc aataaaaatc gaaatcagac tagaaggcta agcgaaagca
    11401 taacttgagt tagctcccat agttcgggaa actatgggag gctggagatg aatcaaagcc
    11461 aagctttgaa ctcattcgta agaagccgac gacgtatcat tttgattttt gaagagtttt
    11521 agaaatacta cgatttttac cttccagata caccatcaaa atagaaatat ctgctgggtt
    11581 tactcccgaa atacggctgg cttggccgat ggtttctgga ttgatgagtt tgaacttctg
    11641 acgggcttcg gttgcgatag aatcaatgtc atcccagtcg atattggccg gaatgcgttt
    11701 ttcttccatg cgtttcatct tggcaacctg gtccatggct ttggaaatat agccttcata
    11761 cttgatttct gtttcaatca attcgataat cttgtcatcc aagtcttctg cagctggtcc
    11821 gatgaaggcc accacatctt ggtaagaaac ttctggacgg cgaaggaatt ccttggctgt
    11881 cactgcatcg gtcaagggtt tgaagcccat ctcctcaacc ttggcattgg tttccttgac
    11941 tggcttaagt ttgatactgt ctaggcgctt catctcatta tcaaattgat ttttcttgat
    12001 ttcaaaacga gcccagcgtt catcgtccac aaggccaatc tcgcgtccca tctcagtcaa
    12061 gcgcatatca gcattgtcat gacgaagaat gagacggtat tcagcacgac tggtcaagag
    12121 acggtagggt tcaatggttc ccttggtcac caagtcgtcg atcatcaccc cgatataacc
    12181 atcactgcgc ttcaaaatca attcaggctt gccttggatt ttcagagccg cattgatacc
    12241 cgcgataatc ccttggccag cagcttcttc gtaacctgat gttccatttg tctgaccagc
    12301 agtgaagaga cctgagattt tcttggtttc caaagtcgca cgcaactgat gaggcaagac
    12361 catatcatac tcaatagcat aacctgtccg catcatctct gcattttcca aacctttgat
    12421 ggaatgaacc aagtcacgct ggacatcctc aggcagactg gttgaaagtc cttgaacata
    12481 gacttcctca gtattgcgcc cttctggctc aaggaagagt tggtgacgtt ccttgtccgc
    12541 aaagcgcaca atcttgtctt caatcgacgg acagtaacga ggccccactc ccttgaccac
    12601 acctgtaaac ataggcgcac ggtggaggtt gttttgaata atctcatgac tggtaccatt
    12661 ggtataggtc aaccagcatg gcacttggtc cttgacataa tcctcatcac gtgaagtgta
    12721 tgagaagtga ttaggcgctt catctcctgg ttggatttct gtcacgtcgt agttgataga
    12781 agaggccttg acgcgtggag gggttcctgt cttgaaacga ccgatttcga gacccagttc
    12841 cttgagattg tcagctaggt taatagaagc caagctgtgg ttaggacctg atgagtactt
    12901 gaggtctccg atgataattt ccccacggag agcagtccct gtcgtcacaa taacagcctt
    12961 agcagcatat tcttgatggg tggctgtacg cacaccgaca accttgccat cttccaccaa
    13021 aatctcatca atcatggttt gacgaagggt cagattttct tggttttcaa ccgtcttgcg
    13081 catctcctta gagtaaagtt ccttgtcagc ctgcgcacga agggcacgga cagctggccc
    13141 cttccctgtg tttagcatct tcatctggat gtaagtcttg tcaatggttt tggccatctc
    13201 gccaccgagg gcatcgactt cacgcacgac aatccccttg gcagaaccac cgatagaggg
    13261 attacaaggc atgaaagcca gcatttcaat attgatggtc gcaagcagga ccttacagcc
    13321 catacggcta gcggccaagg aagcctcaac cccagcgtgt cccgcaccaa ttacaataat
    13381 atcgtattct tcagtaaaat gataagtcat gtttctctcc tattcctcaa gatgaatgtg
    13441 tcttagttgg ccttcccaat ctggtagggc tgtttttaaa aaggctggaa ctagctggat
    13501 attctggagc ttatccaagt caatccactc acagggctgc cttttctcat cttcctgcat
    13561 ggtcaatggg gcatcttcaa gcaaatccac cagataatga aactcgatat tgtgatagga
    13621 aacaccgtat tgttcaaaac gattttcaac cacaaaagct agctgcccag cttgagcttt
    13681 aacacccagt tcttccttca cttcacggac taccgcgtct tccgtgcttt cattgacttg
    13741 aatcgcacct ccaatagtgt aatacttgcc cttgtctttg gtaactagaa gcttgtgatt
    13801 ttggacaatc aaggctgtcg cccgaacacc aaaaaccgta ttgtctactt ttgtccgaaa
    13861 gtcttgttga gtcattcttg tcctttccct taaacgacac aaaaacagtc aaaactacaa
    13921 agaagtgcag gacaaaaaag cctgcaacat ccatgagctt tgaccatcat ttctattgct
    13981 gttattattg tagcaaattg agaaaatttg tcaatctaaa tgtactgaca aacttgtcca
    14041 tcgcggtaag cattgtcaat caaaccacca cctagacact cttcgccatc gtaaaagaca
    14101 actgcctgtc ctggtgtaat cgcgcgttgt ggttccgcaa agatgacctc tgccttgtct
    14161 cctttgacat ggacggtcac cttagagtca ggctgacggt aacggaattt agccgtacat
    14221 tctagcgtaa actcttctgg catttcacga gtaaagtgga cttgactggc ttctaggcta
    14281 gttgacatga gcgaatcatg gtagaatcct tgtcctacat agagaatatt cttgcttaga
    14341 tcttttccga caacgaacca aggggcattg tcaccgccgt gttgcccacc gataccgagt
    14401 ccgccacgct gaccgattgt atagtacata agacctgcat gctcgcccat atcgcgacca
    14461 tccacagtca tcatgcgacc aggctgagct ggcaggtagt tgctgaggaa gtttttaaag
    14521 ttcttttctc cgataaagca aatccctgtc gagtctttct tcttagcagt cgaaaggcct
    14581 gcttcttctg ctagttttcg aacttcaggc ttttccaaat gtcctagtgg gaacatggtt
    14641 ttttgaagtt gttcttgcga aagttggctg aggaaatagg tctggtcctt gccattgtcc
    14701 acgccacgaa gcatgtgaac agtgccgtcc tcatcacgcg ccactcgagc ataatgccca
    14761 gtcgctacat agtctgcccc caaggttatg gcatagtcca aaaaggcctt gaacttgatt
    14821 tccttgttgc acataacgtc cggatttggc gtgcgccctg cacggtattc cgctaggaaa
    14881 tactcaaaaa cgcggtccca gtactctttt tcaaaattga cagagtagta gggaatgcca
    14941 atctggtctg ccaccgcaac cacatccttg taatcttcgg tcgccgtaca gacgccgttt
    15001 tcatctgtgt catcccagtt cttcatgaag ataccgatca catcgtagcc ctgctccttg
    15061 agcaaaagag ccgtcaccga cgaatcaaca ccaccactca tccccacgac aacacgtgtt
    15121 ttagagttat cactcatggt aagtctccca tctattcgtt tattcacgat tgaaggtcgt
    15181 gtgtgcttca cgattgaagg tcgcttgagc agtattcatt ataacacgct tggttagaga
    15241 agacaaggaa gagcttaaaa attgtttttt aaaacttata gtcaatatac agattatgtg
    15301 aatgacgtga gtataccttc ttcttatctt cattcaaata actataataa ataaaacaac
    15361 ccattttctc taatctattt ttcaagttag agaaaaggag tcgtttttta atgacatttc
    15421 ctgaaatcat aagacaggta cctaaagaat acgaacataa atctattcaa tcgaacctta
    15481 tctttgtttc aaaattaaaa tgtcaaatgt tcttaacatg atttaattta atcggcttaa
    15541 acccattcac cgttttcatt tacagtatat ccgtctacag ttgtgttgac tgcaagggca
    15601 cct
//
LOCUS       DBEJJV010000045        15204 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.045, whole genome shotgun sequence.
ACCESSION   DBEJJV010000045 DBEJJV010000000
VERSION     DBEJJV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 15204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15204
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.045"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..134
                     /locus_tag="ACL3GT_001744"
                     /pseudo
     CDS             1..134
                     /locus_tag="ACL3GT_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(268..1236)
                     /locus_tag="ACL3GT_001745"
     CDS             complement(268..1236)
                     /locus_tag="ACL3GT_001745"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0517371.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVAVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1381..2164)
                     /locus_tag="ACL3GT_001746"
                     /pseudo
     CDS             complement(1381..2164)
                     /locus_tag="ACL3GT_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family glutamic-type intramembrane
                     protease"
     gene            complement(2189..2686)
                     /locus_tag="ACL3GT_001747"
     CDS             complement(2189..2686)
                     /locus_tag="ACL3GT_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class carbonic anhydrase"
                     /protein_id="HGR0517372.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2759..4120)
                     /gene="radA"
                     /locus_tag="ACL3GT_001748"
     CDS             complement(2759..4120)
                     /gene="radA"
                     /locus_tag="ACL3GT_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016893792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HGR0517373.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPQNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4134..4649)
                     /locus_tag="ACL3GT_001749"
     CDS             complement(4134..4649)
                     /locus_tag="ACL3GT_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HGR0517374.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4651..5094)
                     /locus_tag="ACL3GT_001750"
     CDS             complement(4651..5094)
                     /locus_tag="ACL3GT_001750"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HGR0517375.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            5399..5548
                     /locus_tag="ACL3GT_001751"
     CDS             5399..5548
                     /locus_tag="ACL3GT_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517376.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            5690..5869
                     /locus_tag="ACL3GT_001752"
     CDS             5690..5869
                     /locus_tag="ACL3GT_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517377.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(6089..6454)
                     /locus_tag="ACL3GT_001753"
                     /pseudo
     CDS             complement(6089..6454)
                     /locus_tag="ACL3GT_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
     gene            6474..6641
                     /locus_tag="ACL3GT_001754"
     CDS             6474..6641
                     /locus_tag="ACL3GT_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzC family protein"
                     /protein_id="HGR0517378.1"
                     /translation="MANTPIKPGTDNQKPGRYVEVGPRGGKVTNGHTATIGKGDRLPP
                     TSAKGNGWKKV"
     gene            complement(6796..6999)
                     /locus_tag="ACL3GT_001755"
     CDS             complement(6796..6999)
                     /locus_tag="ACL3GT_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517379.1"
                     /translation="MRPKRYPYSGQKESTFVKADPELVEKLLRNTSFLECLQKKPINF
                     QIDSEEFKRLSYEAIHDTSQVTQ"
     gene            complement(7022..7213)
                     /locus_tag="ACL3GT_001756"
     CDS             complement(7022..7213)
                     /locus_tag="ACL3GT_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HGR0517380.1"
                     /translation="MPDIANGRERVIAFLKEKGIKKATLAVAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            7784..8152
                     /locus_tag="ACL3GT_001757"
     CDS             7784..8152
                     /locus_tag="ACL3GT_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0517381.1"
                     /translation="MFETFEKIKELAKKRGKALGQVEEDLGYGRNTLYKIKNSTPNAE
                     RIAEIANYFNVSTDYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            8152..8385
                     /locus_tag="ACL3GT_001758"
     CDS             8152..8385
                     /locus_tag="ACL3GT_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517382.1"
                     /translation="MTITINFTEKNSYITDYLNKHGIDTTTMDFDDFMALMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLTREDIA"
     gene            8385..8648
                     /locus_tag="ACL3GT_001759"
     CDS             8385..8648
                     /locus_tag="ACL3GT_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR0517383.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            8661..9041
                     /locus_tag="ACL3GT_001760"
     CDS             8661..9041
                     /locus_tag="ACL3GT_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HGR0517384.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHNSGFYNPDTNVLAIDHNLTPE
                     QQIQVALHELGHKDHTRSEHQNARLRCENEADRNMIHHLVKDALENLDDPTEFDYLKF
                     MSYYNLKTMTNEIMVKEEYLALVN"
     gene            9058..10128
                     /locus_tag="ACL3GT_001761"
     CDS             9058..10128
                     /locus_tag="ACL3GT_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HGR0517385.1"
                     /translation="MEIDKVKADLKQVGKRVADLSQSITNEEQTKNAFIMPFFQALGY
                     DIFNPLEFVPEFTADVGIKKGEKVDYAIILDGEPQILIECKSITENLTKHDSQLFRYF
                     VTTKSKFGILTNGREYKFFTDLDEPNKMDTTPFLTIDVTDIKENQFTEIIKFHKENFD
                     IDNIVSSASELKYLNNLKAFLTENITTPSDSFLRYLTSEIYEGRVTQNILTTFSPIIV
                     KGFNQFITERVNEKLSAALNTSVETKVTTDIPKVEAEAEEIVEVTDEIITTPAELEVY
                     TVVKMLARDVVSPERVFYRDNRSYFNVLVDDNIKKWVLRYRSNSKKSTIEIRDKGIFP
                     VSTPLEVANYANEILEVIKKFS"
     gene            10189..10536
                     /locus_tag="ACL3GT_001762"
     CDS             10189..10536
                     /locus_tag="ACL3GT_001762"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517386.1"
                     /translation="MEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAAIL
                     LQEKIKQKLGEKQHSVSNITFEKLYEEFEENWKHGVKNSTVYASKNVKKEILKQIEGD
                     YLVRNLIDVYYKK"
     gene            10626..11324
                     /locus_tag="ACL3GT_001763"
     CDS             10626..11324
                     /locus_tag="ACL3GT_001763"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0517387.1"
                     /translation="MNYIDTNEMLFVETPRKVITSDELRKKNTKYLDQKEFKLFIQNL
                     KDEALCDYRITKYIRIAKVLFLTGMRYGELAALNYKEDIDFSKKTIHIKHTYDFRQKE
                     RTTPKTIKSDRVITAPQKVLDIIKEQIIENATNGFDTDFIFINTLGEPITNARVICAL
                     KRHGQKIGIEKNITTHTFRHSHISLLAELGIPLTAIMDRVGHSDSKTTLEIYSHVTQK
                     MVSDISSKLDKIKF"
     gene            complement(11407..11500)
                     /gene="ffs"
                     /locus_tag="ACL3GT_001764"
     ncRNA           complement(11407..11500)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACL3GT_001764"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(11533..12000)
                     /gene="tadA"
                     /locus_tag="ACL3GT_001765"
     CDS             complement(11533..12000)
                     /gene="tadA"
                     /locus_tag="ACL3GT_001765"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HGR0517388.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(12201..13487)
                     /locus_tag="ACL3GT_001766"
     CDS             complement(12201..13487)
                     /locus_tag="ACL3GT_001766"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HGR0517389.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(13718..13954)
                     /gene="comW"
                     /locus_tag="ACL3GT_001767"
     CDS             complement(13718..13954)
                     /gene="comW"
                     /locus_tag="ACL3GT_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma(X)-activator ComW"
                     /protein_id="HGR0517390.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            14220..15017
                     /locus_tag="ACL3GT_001768"
                     /pseudo
     CDS             14220..15017
                     /locus_tag="ACL3GT_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15052..>15204)
                     /locus_tag="ACL3GT_001769"
     CDS             complement(15052..>15204)
                     /locus_tag="ACL3GT_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0517391.1"
                     /translation="FGHKLLPLPPYSPEYNPIEKTWAYIKKNLKKVLPSCNTFYEALF
                     SCSCFN"
BASE COUNT         5069 a         3353 c         2513 g         4269 t
ORIGIN      
        1 tgaagaaata tgactttcaa aaaccttcta aaattcctta tcttgaaacg actggtatac
       61 ctactagaat tctccttaga aagcgtcgat tcaagtgcta tcactgttca aaaatgatgg
      121 tcgctgaaac ttctgatgac gtatagtcat atttcttctc tttttattat atcacagttt
      181 taaatctagc tttactagat tcaccgctac tatccattta ttcggaaaaa agacgaaaaa
      241 acctgagaat catctcaggc ttggtcatta aatttttttc tcaatatcga aaagtggaga
      301 aagtggtcgt ttttcatgaa tacgtacgat agcatcccct aggagatgag cgattgaaat
      361 ctgctcaatc ttatcaatca aacgctcttc tggcagatag atggtatcca aaacaaccaa
      421 tttcttaata gctgattttt ggatattgtc cgtagcagga ccagaaagaa ctgggtgcgt
      481 acagcttgca tagactgcaa cagcaccagc ttccgcaaga gcatctgccg catgacaaat
      541 cgttccagcg gtatcaatca tatcatcaat caagatacaa gtcttgcctt caaccttacc
      601 gatgatgttc ataacttcac tagtattcat cttatcaacg ctacgacgtt tatcaataat
      661 agcgatagat gttttcaaaa attctgccaa cttacgagca cgagtcaccc ctccatggtc
      721 cgggctgaca accacatagt cagaaccaac cataccacgc cgctcaaaat aatctgcaat
      781 tagaggagca cccatcaaat gatccacagg aatatcaaag aatccttgaa tttgcgcagc
      841 atgcaagtcg atggtcaata aacgatccac tccagctact tcaagcatat ttgcgacaag
      901 ttttgaagtg attggctcac gcgctctcgc ctttctatcc tgacgtgcat acccatagta
      961 aggcatgaca acattgacag actctgcact cgcacgcttc aaagcatcta ccataatcaa
     1021 aatttcaagc agattgtcat ttacaggcga actagttgat tgtaagataa agacgtgttt
     1081 cccacggatt gattcttcaa tgttgacctg aatctctcca tctgaaaatt ggcgaacact
     1141 tgatttcccc aactctatcc caatctcctg cgccacacgt tctgccaatt ctttattaga
     1201 agaaagggca aacagcttta aatcagaaaa agacatgatt tcctccggta tatatgtatc
     1261 gcttgtgctt ttcacaagat tttccatcta ccattgtagc gctttttgca ctatttttca
     1321 atcaaaaata aaagaagggc accatatttg tacccttgca tcattctttt gaaaaatatt
     1381 ctaggtcatc aactcattgt gtttctcaac aaagcaataa gcatgataat aaccatagag
     1441 agcaatagcc gtaaccactg gaatcgctaa aggcaactct gtttccaact ccacaaaagg
     1501 agagttaaac aataagaccc tgtttcttgc caaccttctg tcctttatag gctctgtaaa
     1561 gcaagtaaac acctactaca gctagacctg aaaaagtcca gtgagaggca attcctgaga
     1621 tgatacgctc taaaattcgc gaaatagtaa agtcaaagcc ctctggcaaa tccgtacgaa
     1681 tataaccaat atcctcaatc atttggaatc ccaaaccgga ggcaattcca agtaaaaaca
     1741 aaaattttaa ttttcgcaca ggaatcaaag ccaaaacaaa aacaagtggc aataatttca
     1801 agggttcttc taccaaagga gccacaatag cactttcaaa ggcatttaaa aatggactat
     1861 ctgggaaaag aacccccagt aaatcatgta tataagtatt agcaaaacta gacaaccagc
     1921 ctgaaaggaa catccctccc aataaagaca gaatcaaaac cttctttggc aattcccatt
     1981 ttttcccaat acggaagaga aaataaagag ccggaatcat gtaaaagaga gctagaaaga
     2041 tagaaactcc cattagtcca tattccgcac ctgacctcga accgtccgta tagtagatgg
     2101 tttcatactg taaaccaata catagcaata aaataaaaat aaataaaata ctgcttttct
     2161 tcatacactt tctttctaaa tgaagtattt ataattctac gactgtcata cttcctgtat
     2221 caacattgta aatagcacca gagataatga catcgtctgg tattagggga gactcgataa
     2281 gcagttgcat atcctcgcgt acactctctt ctatatcttg gaagggcaag aagtcctggt
     2341 ctgacacatc tacacctaat tcctctttta aatactcctg aaaaggttca ttttcaaagg
     2401 tctgagcacc acagtctgta tggtgcaata ccacaatctc tcttgtcccc atttgttgct
     2461 gggaaataac tagcgaacga atcatgtctt cagtcactcg accacctgca ttccgcaaga
     2521 tatgagcatc cccaagtgcc aagcccagag cttgcgcaac gtgcaaacgt gagtccatac
     2581 aggtcacaat ggctactctg gttttaggtt taagtggcag atttaactgc ccatgtaggg
     2641 caacataagc ctgattggct tgcataaact gttcaaaata cgacacgatt ccctccttga
     2701 aaatttgata gtcaaatatt tctcctatct tatcattttt aagagaattt gtcacggatt
     2761 atgcaaagac ctttttcaag acttcctgaa tcgttgtcac gccaatgacc tgaatttcct
     2821 taggcagagt gattcctgtc aaggaattct gaggtacata aatcttagta aagcccagtt
     2881 tagcagcttc gttgatgcgt tgctcaatac gattcacgcg ccgaatctct cctgtcaagc
     2941 ccagttctcc gacaaaacat tcctgaggat tagttggctt gtctttgtag ctcgaagcaa
     3001 tagcaactgc aacagccaag tcaatggcag gttcatccaa tttaacacca ccagcagatt
     3061 tgagataggc atcctgattt tgcaagagaa gccctgcccg tttttccaaa acagccataa
     3121 tcaagctagc acggttaaaa tcaagtcctg tcgtagtacg cttggcattt ccaaacatgg
     3181 tcggtgttac caaagcctga acctccgcca aaatcggacg cgtcccttcc atggttacaa
     3241 cgatggagga accagtcgcc ccatccaaac gctcttctag gaaaacttga ctcggattga
     3301 gtacctcaac caagccgccc gactgcatct caaaaatccc aatctcatta gtggaaccaa
     3361 aacgattttt gaccgctctc aaaatacgaa aggtgtggtg acgctcccct tcaaagtaaa
     3421 gcaccgtatc caccatatgc tccaacatac gaggcccagc caaggttcct tctttggtca
     3481 catgacctac gataaagatg gcaatgttat tggtcttggc caactgcatg agttcagcgg
     3541 tcacttcacg tacctgagaa acagacccct gcacccctga aatctcagga gacatgatgg
     3601 tctggatgga atcaataatg agaaagtctg gctggatacg ctccacttct gcacgaacac
     3661 tctgcatatt ggtctctgca tagagataaa actcactatc aatatcacct aagcgctctg
     3721 cacgtagttt aatctgctgg gcagactcct ccccactgac atagagaact gtccccactt
     3781 gggacaactg ggttgagact tgtaggagaa gagttgattt cccaatccca ggatccccac
     3841 cgatgaggac gagacttcct ggtaccactc cgcctccaag cacacggttg aattcctcca
     3901 tctccgtctt ggttcgattg acattgatgg aagtcacctc agctagtttc atgggcttgg
     3961 ttttctcacc tgtcaaggac acacgcgcat tcttgacctc ggcaacctca acctcttcca
     4021 caaaagaaga ccaagaccca cagttggggc aacgtcccag atatttaggg gaattatacc
     4081 cacaattttg acatacaaat gtcgcttttt tctttgcgat gacaaacctc tttctatatc
     4141 tctaactcac actcaatcac ttggcaaaaa tcaatcttct catttggcac aaactggcgc
     4201 atgagcattc gatgagcaac aactaccaca gtctgatgtt ctcgatactt agacatacat
     4261 tctagaaacc gagacttcat ttccgtagct gtctcatatt gaataggact attaggaagc
     4321 aactccccct tgttttctaa aaacagtctt ctagctgttt caaagttttc tattcctgtt
     4381 ttatagacct gccattcatg taataaaggc tctactctta aaggaagacc cgtagcacag
     4441 accacatacg aagccgtttc taaagctctt gtgactgcag aagatacgat tatttcagct
     4501 gacgagagta aaggattttt gctcaatttc tggacttgct gccgtcccat ctcagacaag
     4561 ggtgccaaat ctatcccaaa tcctatataa gaacgctcct ctaactcacg gtaatctggc
     4621 tccccatgac gtacaaagat aatcttcatt ctagtgccct gtcgatccaa atccaccagt
     4681 tcgaacgcca tcagctgcat ctccatctgc aattaagaaa gtagcaaaaa cagcctggac
     4741 aatacgttcc ccaacttcaa gaacaacctc ttgatctgtg atattcttca tctgcgcaaa
     4801 aatatgccct tcatttccag gatttccata ataatcccca tcaatgaccc caactgagtt
     4861 aattaaaacc aagcccttct tacgaggatt tgaagaacga tcatagaggt agagaacctc
     4921 agtcggctgc atataagcct taacccctgt cggaaccaag acaatctctc ctggcgcaac
     4981 aactgtacgc acagcaacct ttaagtcgta accagccgca tgcgctgtct cacgcttggg
     5041 caataaattt tcatctgtaa aactcgaaac caattcaaaa ccacgaattt tcataatttt
     5101 ctcttttcta ttatcattta ttctagatta ttctatctta tttattcgga aaaagcacga
     5161 aaaaaagagc acacaacaat tataggcgat acgataattt acactgtttc acaatacgtt
     5221 gaaatttaga gctttaaagc gagggcaaag ttgatttttt acatcgtttt acagaggttt
     5281 acgacacttt tgcccctttt ttgccccttt gtttttcaaa aaaacttcat caaatcgctt
     5341 gactttcacg gtttaccgtg atataatata atcaagataa ggaaaggagg tgaggaagtt
     5401 gaacaaagaa gattggctta ggttactgga aaaggcgata gataatatcc ctgaaacggt
     5461 aactgctata gcaagtctgg tgactgcaat aacggtcgca aggcaaaaca aaaagcgtaa
     5521 accgaaatcc cgtcaaagaa aaaggtgaac gctaagaggt tggggcgaaa gcccctcaca
     5581 cctctatttt atcaaatgaa aagaggaaaa gcaatggtta gtgcaatagc tatttttata
     5641 attgcggtca atgtatatat ttatctaaaa aataaaaagg acaaataaga tgagagaagt
     5701 tattcaagaa ttgttagaca gttcgatgtc tacatctgct atttcccaag gtgctggagt
     5761 tccatggact actgtttctg acctcagaaa aggaaaaaca agcatggaca aaatggcact
     5821 tctcacagca gaaaaacttt atgaatttgc tacaactgat aagcagtgat ttcggtcact
     5881 gtttttattt ttgacaaaac accgtttttg acaataatca aaaaataaaa aggagctatt
     5941 attaacaaaa tggcgttttt ggcaataata ccctgccatt cctcctccct attcttcaag
     6001 aaaacgcttt tttgaagaat cagagcaaat aaaaaaccgc aagcctgagc ctgcggtgaa
     6061 agaacaattt agaaagtttc ctttctattt atttaactgt aatcaagcca tctggctcta
     6121 ctgtgaactc tggcttgtct gccagtgttc cgtctggttt gaggtagtac cagcctgttc
     6181 cgtccgctga ctggataaag gcatttgata ccatggcgcc ttctttagcg tctaagtagt
     6241 accaagtgtc cttgtacttg acccagcctg tcttcatggc accttctaca tcaaaatagt
     6301 accacttgtc agcgattttc ttccagcctg tggccatttc gcctgattgg tcaaagtagt
     6361 accaattacc gtctgtgtgc ttcttccagc ggtctgaaag catatagcct gagccatcga
     6421 aataatacca gataccgttg attttctcaa acttatagaa aggaggagat agtatggcaa
     6481 atactccaat aaaacctgga acagataatc agaaacctgg tcgctatgta gaggtaggac
     6541 ctcgtggcgg aaaagttact aatggtcata ccgcaactat cggaaaaggt gatcggctcc
     6601 ctccgacatc tgctaaaggc aacggttgga aaaaagtcta atcttcgttt gcgtacaatc
     6661 gttcaatggt tgtacgcttt ttccatacac aaaagcacat tcccaaaaaa tcaatttgaa
     6721 tccatgcttc ggcgtaatct ttcccattgc tggcatagtg agttatataa tggtgaatca
     6781 ttttattcct tcctcctatt gagttacttg agaagtatca tgaatggctt catagctaag
     6841 acgcttaaat tcttctgagt ctatctgaaa attgataggc tttttttgta aacactcaag
     6901 aaaactagtg tttcttaaaa gtttttcaac taactcaggg tctgccttta caaaggtgga
     6961 ctctttttgt ccactatacg gatatcgttt tggtctcatt ttcctactcc tcaaatcttt
     7021 cctactcaat cccataatct tcaataacct gaagaatgaa actgttcgct cgtggacctt
     7081 tagtcgttcc acttagaatg tttgtcactt cctgtcgttt aaagccgtaa gcaaccgcta
     7141 gagttgcttt tttaatgcct ttctctttca agaaagcaat aactctttcg cgaccgtttg
     7201 cgatatctgg catattttct cctttctttt tctttcttct ttttctgcta taatataagc
     7261 agaaaggagt taaccttatg acttttaaag aatatttact caaagcaagc aaacgcgaca
     7321 tctacgatga tggtaaagat tttgagaaat caatttcaga ttctcactaa tcgagcgtga
     7381 cttttttgat atggcaatct cagaaattta ccaccagcgc tgactacctt aatgactttt
     7441 tcaaggtggt ctttttcttg ttctaaattt ttaagaatac ttaccatcag cacgttcctc
     7501 ctctttactt atttgtaaat aagaaacaac taaaaatgta actatttttc tgcattatac
     7561 ttgacaactt acaccaaatc ggctaaaatt aaagcataat aaaaacacca ataaatctat
     7621 aaataccgtt cgccaaaaca tttttataat ttatttctta gttgtttttt tagttgttta
     7681 tcacttacaa aaaacatttt acaccttttg ggataattag tcaacctttt tacaccaaat
     7741 ttgttaaatt tttttgtgat gtcttagaaa ggttgattta acaatgtttg agacatttga
     7801 aaaaataaaa gaattggcaa aaaagcgtgg aaaagctctt ggacaagtag aagaagactt
     7861 aggttatggt agaaatacac tctataagat aaaaaattct acgccaaacg ctgaacgtat
     7921 cgcagaaatt gctaattatt tcaacgtatc caccgactac ctgctcggac gaacagataa
     7981 ccctgctatc gctgggagtg atgaatttgc ccaagtaaac ggacaaatca tagacttacg
     8041 caaagcagca gccaacacca tgttatttga cgggaaacca ctaaatgaag atgatatcga
     8101 cttcattaca tccgtcctat ccgcccactt caaaagcaaa ggagaacgct aatgactatc
     8161 actatcaact tcacagaaaa aaattcctac attacggact acctaaacaa acacggtatc
     8221 gacacaacga ccatggattt tgacgacttc atggcactca tggaagatat cgaagacgca
     8281 cgagcagccg accaagccta tatggagtat ttagccgacc cagctactta taccatggat
     8341 gaggtcttgg atgaactagg actaactcga gaggatattg cttaatgtat cggctagata
     8401 ttgataaaaa agctctcaag caacttaaaa aactagatac cccaaccaga aaacaaatcc
     8461 tatcctggct tgctaaaaac attgaaaaca cgaccaatcc acgacaacac ggaaaagcac
     8521 taaaagccaa ccttgcaggt tactggcgat acagagtaga gaattaccgc atcatctgtg
     8581 atatccaaga cgataaacta gtcgtcctag ccgtggaaat cgcccaccgc agagatgtct
     8641 ataaataacg aaggagaact atgacactcg ctaaactctg cgaagaatat caagtagaac
     8701 tttgtctctt cgacggttca aactggcaca atagcggttt ctacaatcca gacacaaacg
     8761 tgctcgctat tgaccacaac ttgactcctg aacaacaaat ccaagtcgcc ctacacgaac
     8821 ttggacacaa agaccacaca cgctcagagc accagaacgc ccgtctacgc tgtgaaaacg
     8881 aagctgatag gaatatgatc catcatctcg taaaagacgc tctagaaaac ttagacgacc
     8941 ccacagagtt tgattacctc aaattcatgt cttactacaa tctaaaaacc atgacaaatg
     9001 aaatcatggt taaagaagag tatttagcat tagtaaatta aaaaaaggag tatcaatatg
     9061 gaaattgata aagtaaaagc cgatttaaaa caagtcggca aacgtgtagc agacctcagc
     9121 caaagcatta cgaatgaaga acaaacaaag aatgccttca ttatgccgtt cttccaagcg
     9181 cttggatatg atatcttcaa tccacttgaa tttgtcccgg aatttactgc cgacgtgggc
     9241 attaaaaaag gcgaaaaagt cgactatgcg atcattttgg atggcgagcc tcaaatccta
     9301 attgaatgta aatcaattac agaaaacctt actaagcacg actctcaact attcagatat
     9361 ttcgtaacta ctaaatcaaa attcggtatc ttgacaaatg gtagagaata taaattcttt
     9421 actgatttag atgagccaaa taaaatggac acaactccat tcttaacaat cgatgtgact
     9481 gatatcaaag aaaatcaatt tactgaaatc atcaaattcc acaaagagaa ttttgatatt
     9541 gataatattg tttcatcagc ttctgaattg aaatacctca acaatcttaa agcgttcctt
     9601 actgaaaata tcactacacc gtcagatagc ttcctcagat atctaacttc tgaaatctat
     9661 gaagggcgtg ttactcaaaa tatcttaacg acattttctc ccattattgt gaaagggttt
     9721 aatcaattca tcacagagcg agttaatgaa aaattaagtg ctgcacttaa tacaagcgtt
     9781 gaaaccaaag taacaaccga tattccaaaa gttgaagctg aagctgaaga gattgtcgaa
     9841 gtaactgacg aaattatcac aactcctgct gaattagaag tttatactgt tgttaaaatg
     9901 cttgctaggg atgtagtttc tccagaacgt gtattttaca gagataaccg tagctatttc
     9961 aatgttttgg ttgacgataa catcaaaaaa tgggtattac gttatcgttc aaattcaaaa
    10021 aaaagcacta tcgaaatccg tgataaaggc atcttcccgg tgtctacccc tctcgaagtc
    10081 gcaaattatg ccaatgaaat tttagaagta atcaagaaat tctcataata aaaaaagccc
    10141 tctttactat acccatttta tcaaaaaagt gaggtaaaat caatgtggat ggaagaattg
    10201 ccaaacggca aatataaatt ttttgagaga tacaaagatc catatactga gaaattaaaa
    10261 aaagtctcag taacgatgga gaaaaaaact ccccaagcaa gaaatcaagc tgcgatttta
    10321 cttcaggaaa agataaaaca aaagttagga gaaaaacaac attctgtttc taatataact
    10381 tttgaaaaac tatatgaaga atttgaggag aattggaaac acggcgtaaa aaactcaacc
    10441 gtctacgctt caaagaatgt aaaaaaagag attttaaagc agatagaggg cgactaccta
    10501 gttagaaatt tgatagacgt ttattacaaa aagtaataga tcaactatta caagatggga
    10561 gatctcataa ctatgtttct aaaatcaaat tcaagctcaa tcagataatg aaatttgcta
    10621 tcagaatgaa ttatattgat acaaatgaaa tgctatttgt tgaaacgcct agaaaagtaa
    10681 ttacatccga cgaactcaga aagaaaaata caaaatactt agaccaaaaa gagtttaagt
    10741 tattcatcca aaatttaaaa gacgaggccc tatgtgatta tcgaattaca aagtatatcc
    10801 gaatagctaa agttcttttt cttactggca tgaggtatgg agagctggca gccttaaact
    10861 acaaggaaga tatagatttt tctaaaaaga ctattcacat caagcataca tacgatttca
    10921 gacaaaaaga gagaactaca ccaaagacaa tcaagtccga tagggttata acagcacctc
    10981 aaaaagtgtt agatattatc aaagagcaaa taatagagaa tgcgacaaat ggatttgata
    11041 cagattttat tttcatcaat actctaggag aaccaataac aaatgccagg gttatttgtg
    11101 cattgaaaag acatggtcaa aaaatcggca tagaaaaaaa cataactaca catacattta
    11161 gacattctca catatcccta cttgctgagc tgggcattcc cttgactgcc atcatggaca
    11221 gagtagggca tagtgactca aagaccacac tagagattta ttctcacgtt actcaaaaaa
    11281 tggtatcaga catatctagc aagttagaca agataaaatt ttaaattgtg cccctcgtct
    11341 gccccttttt cttatacaag acaaacaaaa accccttaaa gtgttgattt taaagggttt
    11401 ttaaagtgca cgaaaaaaga gcacacaatt caaatcgctt agggctgctg gattcctccc
    11461 ctgacccgct tcacgcagaa ctgttgctcc actatttatt atatcacatt cctattcatt
    11521 ttaaaagcaa aattattttt tccgtctatt tctaaaaaaa tcctgcatga tagctgcgca
    11581 ttcatcttcc aaaattccta tttcaacctc cacacgatga ttgagacgct catctgtcaa
    11641 gatatcgtac aaactcccag cagcgccaaa tttctggttt ttagccccat agaccacatt
    11701 tggaatgcgg gcaagcccaa tcgccccact acacatgaca caaggttcaa tggtcacaaa
    11761 aagtgtgcaa tccagcaagc gccagctctc ctcactcaag ttcgcatcct ctatagccat
    11821 aatttccgca tgcataaccg ctcgctgtaa ttcctcacgc gcattatgcc cacgaccaat
    11881 gatttcccca tctttgacaa tcacacaacc aattggaatt tcatcgtgtt caagagcaat
    11941 ctcagcctct ctcaaagcct ccctcataaa gacttctttt tcttcaagcg tataatacat
    12001 ctcttttctc ttttcctact tatcgatttt attattatat catgaatccc aacacaaaag
    12061 aagccaccga atgcggtgac tctataggga gattattatg aaaaagaaaa gtttaggata
    12121 tttgttacaa caagttagga ggtcttcttg taactgtcta tagtataccc gacctatctt
    12181 aaacaaatct taaaaatctc ttaggaccaa acactttcta aaatatttgt ttgttcacga
    12241 ccaggaccta ctgagaaagt agaaatacga acgccaacca attcactcac acgacgaaca
    12301 tagttacgcg cattctcagg aagatcttcc aaattgcgaa ctccggtaat atcttctgac
    12361 caacctggca actcttcata gataggcttg caacgtttca attgctcaag actagctgga
    12421 tagtagtcaa tacgttgacc gtcaagatca taggccacac agattttcac agtatccaaa
    12481 ccgctcaaaa catcaataga gttcaaagaa aggttagtaa taccagaaac acgacggcta
    12541 tgacgcatca caactgagtc aaaccaacct acacgacgtg gacgaccagt tgttgtacca
    12601 tactcatgac ccacttcacg gatacgttct cccacttcat caaacaactc agttgggaaa
    12661 ggaccatctc ctacacgact cgtataagct ttacatacac ctacaacctt gtcaatcttg
    12721 cttggaccga caccagaacc aattgtcaca ccaccagcta cagggtttga tgacgtaaca
    12781 aatggataag taccttggtc gatatctagc ataacacctt gtgcaccttc aaaaagcaca
    12841 cgtttgccat tatcaagcgc atcattcaag ataacagatg tatctatcac gtatttcttg
    12901 atttgttgac catattcgta atattcttca aaaatatcat cgaaaacaat cgctttactg
    12961 tcatacaatt tttcaaaaag acgattcttt tcagcaaggt tacgttctaa acgctcacgg
    13021 aaaatatctt tatctaaaag atctgcaata cgaattccaa cacgagcagc cttgtccata
    13081 taagctggac caattccctt aattgtcgta ccaatcttat tgtcgccctt agcttcttct
    13141 tgcaagcgat ccaactcgat atgataaggc aaaataacat gcgcacgatc agaaatacgc
    13201 aagttatcag ttgttacacc ttcctcatga agatagctca actcttttac aagagattta
    13261 ggatttacaa ccataccatt cccaatgaca gatatttttt cagggaagaa aatcccagat
    13321 ggaatcaagt gcaacttaaa tttcttaccg tcaatcacaa tcgtgtgacc agcattatca
    13381 ccaccttggt aacgtgcaat cacttctgca ttcgctgaaa ggaagtctgt aatcttccct
    13441 ttaccttcat caccccattg ggtacctaca acaacaactg aagtcataat tttgtctgag
    13501 ccctcaggct cttcctttct cacatacatg gcaggactct cacctgcaat tatatcttac
    13561 aatttattat aataaaaaat cgccttttta tcaagaagaa acaatagaaa gatttgctat
    13621 ttccaactat taaaaaatga tttagaaaaa ttactagcta tttactatta tctttacata
    13681 aaagagtaaa ttagttcgga aatttactaa aattacctca acaagaaata aaaccccgat
    13741 tcattaccaa tttttcaaga tacaaacgat aagcaacacg ataatggtaa acgataaaat
    13801 ccctatgaca accaatgcca tatctcacta aataataaat taaaaattta aaatgaacat
    13861 gttcccagtc aaaattatca ccaaatgtag gaccatactc ttcttcaata ctatcataga
    13921 aattagccat ctgctcataa attttttgta acataatcaa atactccttt tcttttttat
    13981 aaacttattc taacaaaaaa ttttacacat tcactatcaa ttcctgaatt gttaaaatac
    14041 cagcctcaac aagataaaaa taggaaaagt tgacaaaata gaaacaaatt tgctacctaa
    14101 atttcaaaca attaaagttc taaaaagacc gccttaaaac ttttgggtaa atcctattag
    14161 aactataata tttttatata ggtattatgg ttctgatttt ctagtataaa aaaattcaaa
    14221 ctagaattct tcttagaaaa ggccgtttta agtgctatca ttgctcaaaa atggagctcg
    14281 ctgagacttc tatcgtcaag aagaatcatc aaattccttg tatcatcaac caaaagattg
    14341 ctcaaaagtt aattgaaaag atttctatga ccgacattga tcatcagttg tctatttcaa
    14401 cttcaactgt cattcgcaag atcaataatt ttcactttga gcatgatttt tcgcgtcttc
    14461 ctgagattat gtcctaggac gttgaaacag tccggggagt gactgtttca atcgggagat
    14521 ggagatgagc tttattgctc aggactttga taaactcaat atcataactg ttcttgagag
    14581 cagaacacaa gccatcatcc gaaatcccat gaatacaagg ctatcaagcg ctactggaag
    14641 ctcattcaac aagatagtca gaaactgagt gataaacgat tttatcgccc tacttttcgt
    14701 atgcacttga ctaataaaga aattctagat aaacttttga gctattccga agacttgaaa
    14761 caccactata atctctatca gctcttgctt ttccacctct gtttcagact ttgtttaaaa
    14821 ccttcctcaa agataaagag aaaatcgtca acgcccttca attaccttat tccaacgcca
    14881 aactggaagc caccaataat ctcatcaaac ttatcaagca caatgccttt ggttttagga
    14941 actttgaaaa cttcaaaaaa gaaaggacga aatttgtcct ttctagatct tcgctttctt
    15001 caacccacta cagttgacaa agaaccgaaa aatgtctcgc ctctaatata gtcaattgaa
    15061 acaagaacaa gagaaaagag cctcgtaaaa ggtattgcaa cttggtaata cctttttgag
    15121 gttctttttg atataagccc atgttttctc aataggattg tactcaggtg agtagggagg
    15181 aagaggtaaa agtttatgcc caaa
//
LOCUS       DBEJJV010000046        14833 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.046, whole genome shotgun sequence.
ACCESSION   DBEJJV010000046 DBEJJV010000000
VERSION     DBEJJV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14833
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.046"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(153..1775)
                     /gene="groL"
                     /locus_tag="ACL3GT_001770"
     CDS             complement(153..1775)
                     /gene="groL"
                     /locus_tag="ACL3GT_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HGR0517392.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(1791..2075)
                     /gene="groES"
                     /locus_tag="ACL3GT_001771"
     CDS             complement(1791..2075)
                     /gene="groES"
                     /locus_tag="ACL3GT_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HGR0517393.1"
                     /translation="MLKPLGDRLVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(2231..2626)
                     /locus_tag="ACL3GT_001772"
     CDS             complement(2231..2626)
                     /locus_tag="ACL3GT_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HGR0517394.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EVDFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(2704..3465)
                     /locus_tag="ACL3GT_001773"
     CDS             complement(2704..3465)
                     /locus_tag="ACL3GT_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HGR0517395.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(3507..4133)
                     /gene="ytpR"
                     /locus_tag="ACL3GT_001774"
     CDS             complement(3507..4133)
                     /gene="ytpR"
                     /locus_tag="ACL3GT_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HGR0517396.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFETAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDSAKHWTA"
     gene            complement(4149..4466)
                     /locus_tag="ACL3GT_001775"
     CDS             complement(4149..4466)
                     /locus_tag="ACL3GT_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HGR0517397.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(4463..4762)
                     /locus_tag="ACL3GT_001776"
     CDS             complement(4463..4762)
                     /locus_tag="ACL3GT_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HGR0517398.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(4960..5040)
                     /locus_tag="ACL3GT_001777"
     CDS             complement(4960..5040)
                     /locus_tag="ACL3GT_001777"
                     /inference="COORDINATES: protein motif:HMM:NF039231.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517399.1"
                     /translation="MASSGKMLRNTYTPDGYYVGNLGAWQ"
     gene            complement(5047..5238)
                     /locus_tag="ACL3GT_001778"
     CDS             complement(5047..5238)
                     /locus_tag="ACL3GT_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HGR0517400.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(5399..6073)
                     /locus_tag="ACL3GT_001779"
     CDS             complement(5399..6073)
                     /locus_tag="ACL3GT_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517401.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(6079..6525)
                     /locus_tag="ACL3GT_001780"
     CDS             complement(6079..6525)
                     /locus_tag="ACL3GT_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="HGR0517402.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPCYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(6639..7142)
                     /locus_tag="ACL3GT_001781"
     CDS             complement(6639..7142)
                     /locus_tag="ACL3GT_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HGR0517403.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMSLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVTLSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(7139..7501)
                     /locus_tag="ACL3GT_001782"
     CDS             complement(7139..7501)
                     /locus_tag="ACL3GT_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HGR0517404.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(7567..7716)
                     /locus_tag="ACL3GT_001783"
     CDS             complement(7567..7716)
                     /locus_tag="ACL3GT_001783"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517405.1"
                     /translation="MSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNSQFTE
                     DEAEE"
     gene            complement(7744..9468)
                     /locus_tag="ACL3GT_001784"
                     /pseudo
     CDS             complement(7744..9468)
                     /locus_tag="ACL3GT_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731792.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(9443..9914)
                     /locus_tag="ACL3GT_001785"
                     /pseudo
     CDS             complement(9443..9914)
                     /locus_tag="ACL3GT_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
     gene            complement(10038..10754)
                     /locus_tag="ACL3GT_001786"
     CDS             complement(10038..10754)
                     /locus_tag="ACL3GT_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HGR0517406.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11635..13050)
                     /gene="ply"
                     /locus_tag="ACL3GT_001787"
     CDS             complement(11635..13050)
                     /gene="ply"
                     /locus_tag="ACL3GT_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HGR0517407.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13061..13471)
                     /locus_tag="ACL3GT_001788"
     CDS             complement(13061..13471)
                     /locus_tag="ACL3GT_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517408.1"
                     /translation="MIKRGDVVALYLPFPTISSDLAVKNHMYICIDNSMTKNKELVKN
                     QTFKPALLTRRLVKNFMIEEPDLARNPFTRPTLIDLDKVFMLDNTGIPTSYLARRRRN
                     VSEELYEEILDYLVQPRLISLNKSEFMQLNPGTY"
     gene            complement(13464..14072)
                     /locus_tag="ACL3GT_001789"
     CDS             complement(13464..14072)
                     /locus_tag="ACL3GT_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517409.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14085..14543)
                     /locus_tag="ACL3GT_001790"
     CDS             complement(14085..14543)
                     /locus_tag="ACL3GT_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HGR0517410.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14668..14778
                     /locus_tag="ACL3GT_001791"
                     /pseudo
     CDS             14668..14778
                     /locus_tag="ACL3GT_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         4319 a         3430 c         2686 g         4398 t
ORIGIN      
        1 atcgccctga atatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagctgact
       61 tcaacccact acagttgaca aagagcctat aaaaagaagg gttagtcatt ccctcctttt
      121 gtgtttttta taagttgttt tctatagaaa gcttacatca tcccgcccat catacttgga
      181 tccattgctg gagctggggc tactggttct ggtttattgg ctacgactgc ttctgttgtc
      241 aaaatcaagc tggctacaga tgctgcattt tgtagggctg aacgactcac tttaactgga
      301 tcaatgatac cttgatcaat catgttaacc cactcgccag ttgctgcgtt aaatcctata
      361 ccaagctcag catttttcaa acgatcgata acgatagatc cttcaaatcc tgcattgtga
      421 gcaatttgac gaacgggttc ttccaaagca cggagaacaa tattacgtcc tgttgcttca
      481 tctcctgtca attccaaggt agcaacagct ggaatcacat tggcaagagc tgttccaccg
      541 cctgcaacaa taccttcttc aacagctgca cgagtagcgt tgagggcatc ttcaatgcgg
      601 agtttcattt ctttcaactc agtttcagtt gcggctccga ccttaataac cgctacacca
      661 cctgacaatt tggccaagcg ttcttgcaat ttttcacggt caaattcaga agttgtagtt
      721 tcgatttgag acttgataac cgcaacacgg tgagaaatcg cttcaggatt tcctgcacct
      781 tctacaataa ccgtgctatc tttgtccacg gtcactctcg ctgcttgacc aagagcttca
      841 attgtcgcat ctttcaactc aagaccaagg tcttctgtga taactgttcc gcctgttaag
      901 atggcgatat cttcaagcat ggctttgcga cggtcaccaa aaccaggtgc cttgactgct
      961 actacgttga aggttccacg aatcttgttc aaaacaagag ttggaagagc ctcgccatcc
     1021 acatcatccg caataatcaa gagtggacga ttgctttgga gaatgctttc caaaagtggc
     1081 aagatctctt ggatattgga aattttcttg tctgtaatca aaatgtacgg attttcaagg
     1141 tcagccacca ttttttcgct atctgtcacc atgtactgtg aaaggtaacc acggtcaaac
     1201 tgcattcctt ctacgacttc aagctctgtt tccataccac gtgactcttc gatggtgatg
     1261 acaccgtctt tgccaacttt ttccattgct tcagagatgt actcaccaac tttttcagaa
     1321 cgagaagata cggctgcaac ttgagcgata gcttctttat tggcaacagg gatggcgttg
     1381 tttttcaaag cttcaactgc tgcggcaact gctgtttcaa tcccacgacg aataccgatt
     1441 ggatttgcac ctgctgtgac gtttttgatt ccttcacgga cgatagcttg ggtcaagact
     1501 gttgcagtcg tagtcccgtc acctgcgata tcattggttt tagaagctac ttctgatacc
     1561 aatttggcac ccatattttc aaaatggtct tctaattcaa tttctttggc aatagtcaca
     1621 ccgtcattgg taatcaatgg tgagccaaat gatttttcaa gaacgacatt gcgacctttt
     1681 ggtcccaagg ttactttaac agtatctgca aggatatcga caccacggac catagctgaa
     1741 cgggcatctg atgaaaattt aatttctttt gacatactta ctttctcctt ctattcttca
     1801 atgattgcca agatgttagc ttcgcctacg atgatatact tttcatcgcc atctttgaca
     1861 tcaagacctg cgtgggcttc aactaagaca cggtctccag ttttaacact tggagcaacc
     1921 aagtcaccgt tcaaggtacg aacaccttgt ccagtagcca caacttgggc tgttttggtt
     1981 ttttcttggg ctgaacctgc gagaacaaag cctccaacag tttgttcttt ttcttctact
     2041 tttaagacca aacggtcccc taatggtttc aacatctgat ttcctccata atgagataga
     2101 tattattagc actctttata cctgagtgct aattcatagt tctattgtat cacttagtca
     2161 gaaataatca agaaaaaagt ctgactttct caagataaaa agcctgagac caactcagac
     2221 tttttaattc ttaaaatggc aattcttcct cttccaagac caaatctgcc aaatcttggc
     2281 ctgcattatt ttcacgcata gcacgttggg cacgactttc caagagttgg aatcctgtca
     2341 caaggacttc ggttacataa ttcatctgac catttttctc aaagcgacgg gtacgcaatt
     2401 ctccatcaac ggaaatgaga ctacctttgg ttgcgtagct tgccaaagtt tctgctagtc
     2461 tgccccatag gaccatattg acaaaatcaa cttcacgttc accgttttgg tctttgtaac
     2521 gacggttgac agcgatagtt gctcgcgcta ctgacttgtc attgttggtt ttgtgcaatt
     2581 ctggtgtaga cgttaaacgt ccaatcaaga taactttatt atacatattt tcttcctcct
     2641 acttatctat tcgtaggaaa tcaaaaaaag ttacagaaat ttgtaacttt tcgagaaaat
     2701 tttttatttt ttatgaacca tgaaacctgt cgcctgttga ttggccataa tggtcatatc
     2761 tgtaatctga acacgacgag gttgactagt cacatagact actgtatctg caatatcctg
     2821 agcttgcaaa gcttctattc cttggtaaac ggacgcagct cgttctttat caccatgaaa
     2881 acgcactgta gaaaaatctg tttcgacaat tccaggctga atggttgtca ccttgatatc
     2941 cgttgcgatg gtatcaattc gcagtccatc cgaaaaggtc ttaaccgcag ccttggtagc
     3001 tgagtaaaca gcggcaccag cataggcgta gattcctgcg gttgacccca tattgataat
     3061 atgaccttga ttgactttta tcattgctgg caagaaacag cgagtaaccg ccatcagacc
     3121 tttaacattg gtatccaaca tggtcaacat atccaactcc tcatagtctt gatagggagc
     3181 caagtcaaga gccagtccgg cgttgttgac caagatatca atcctcccta tcgtttctag
     3241 aatatcagag caaacagtct tcaccatgac catatccgtc acatctagtg gaaaagtcca
     3301 gacggtttga tttggaaagc ttactgcaaa ctccgacttg aggatttcta atctgtctat
     3361 ccgtcgtcct gttagaacga catcctcacc ctgctccaga taagcacgcg caatcgcttc
     3421 accgattcct gaggttgctc ccgtaatcac aacatttttt gccatcttat ttccttctag
     3481 ctggtctatc agatattaac aacttcttag gcagtccagt gtttagctga gtcaaatggt
     3541 gttccgacaa cttggtcttc tgataattca agcaccccac gtttttgtgg agcatttggc
     3601 agatgcaatt cacgaggact gcacatcata ccaaaactct tttcaccacg aagttcacct
     3661 gggaaaatga gattcccttt tggcatcata gctccaggaa gcgcgacaat ggttttcaac
     3721 cccacacgcg cattgggagc tcctgcaacg atttgtacag tcttatcact tgcgactgca
     3781 acttggcaga tgttgaggtg gtcactatct ggatgggcta ccatctcaac aatttcaccg
     3841 acaacaaact taggttcctt atcattaaca atttcttctg taaaaccttc cgcctgcaac
     3901 tcttggttca aacgagcgac ttgctcatct gtcaaaaaga cttgaccgcg ctctgcagtt
     3961 tcaaataaac ttgaaacttc gaaaatattc caagccactg tttccccatt ttctttgagg
     4021 aaaacacggg ctaccttgcc tttgcgttcc acattcagtt tggcatctcc gctatttttc
     4081 acgatgacca taaggacatc accgacatgt tctttgttat acgtaaaaat cattgtttcc
     4141 tttttctcct atttcaatcc tgctaaaaaa tcgttaattt gctccttact tttacggtcg
     4201 cgattgacaa aacgaccgat ttccttgtcc ttttctagaa caacaaggct aggaattccg
     4261 taaacatccc agagtttggc caaatccata tactgatctc ggtccattcg aataaaggtg
     4321 aactctggat tggtctcttc aatctctggt aaggcaggat aaatataacg acaatcgcca
     4381 caccagtctg ccacaaaaag gaagaccttc ttgcccgctt tttccactaa agatgctaat
     4441 tcttctaaac ttgctggctg tatcataaga cttcctcctc atagactagg tcttcatttt
     4501 catagacaaa ggtataatga cggccatcct caaaaatgac gccaccaacc aagctctcca
     4561 gactgctttc gtaaacttga acataaaggg tcgcaatttc ccccatgtcg gaaaaatggt
     4621 ctcgcacaat ctctgtcaac tcttcctgag tcttcatgag cttacggtca tctgcaactt
     4681 ttttcgtagc aagggcaagg cttccgatac ctagcagagc caagcctgcc atccacattt
     4741 ttttagcttt cataccattc attttaacac aaaaaaggct tcaggacaaa tgaggaagca
     4801 gcagaaaagc aagtaaaaag cctcttcctt taaggaaaag gacttcttat actaagagca
     4861 aactagaaag ctagccgcag gctgctcaaa acacggtttt gaggttgtag ataaggcgac
     4921 gttgacgtgg tttgaagaga ttttcaaaga gtattattct tattgccagg cacctaagtt
     4981 gccaacgtag taaccatcag gtgtgtaggt attgcgaagc atcttacctg atgaagccag
     5041 ataatactac ttgccattgt ctttgaccca atcattcgca atcatggaac cagaagaact
     5101 tacataatac cattctccct tgtcataaac ccaagtactg actttcatgg ttcctgagca
     5161 attaaaggca aaaaaactgt ccaatatcat tcgtttttta aaagcattcg acactacatc
     5221 atctacgctg tagtacatag atacatcaaa cgtaaaagcc aaaatatcga aaaatataca
     5281 acttttaaag gcagcatttc attttttaaa gtctaacaac catagaactg aaatcagagc
     5341 aaggcatcaa tttcctactc tatagtacgc ctattttgat ggttgaagtg aagatttttt
     5401 atttaacgta gacaatttcc aacttcccaa aagccacatc tccacggata atcaaggttt
     5461 tgctggttgg ggctacagga gcgtcagcct tagctgcacc aaaggaggtt tctactttca
     5521 aatctacacg ccagtgttgt ggaacataga cggttgcatt tccgaaggct acttcaatat
     5581 ttaaagttgc aaaatcacct agcatctctg cattatcata gtagatttta gcatccccaa
     5641 aagcgacttc cacttggtca tctacgagat cttgatcttg cttatagaag gtcccgctac
     5701 caaaagcgac ttccttatcc gtgacgactg tttttttccc attgtaccac catttttttt
     5761 cattccagaa cttacttgaa tgcgtcagat aaccaacacc aagtaccacc aagatgctag
     5821 cccaaataag agaatgattg gtaactggta acaagtcata agcgtaattt gcaatgatga
     5881 gcgccagtaa acctgtaaaa actgccgaag tgagatgacg tctaaggatg gactcaatgg
     5941 acttataagc aaaaaaaaca atacctagta aaggccatat tttaccatcc aaagaaggaa
     6001 ttccaaaatt cccttgcagc aagatccaag ctgctaaaac caataaaaca ataccaaatg
     6061 ctttcttttt catgtttttt acctcatgtt tcttagattt tcttttagga gggattggta
     6121 atgccgtgag acatgaacct ccttgtgcgt ctgataaaag gaaatggtgc ccgttcctga
     6181 aaaggacttg tccactgagt aaatctgacg gatgtttgcg atcgttgact tggaaactcg
     6241 attaaaatag caaggcaaga tagactccaa ctcatagagc ttgaggcgaa cctcataagc
     6301 ttccttctgg ttatgagcgt agatcttgct cccttctgtt tcaaagaaga gaatttctga
     6361 caggtctaga taatattcac ctgtcccctt gtaaaaagtc aacctcggag cctttgactc
     6421 ttgcaagagc cgttgcaagt ctgcaatttc atctgtcaaa gtgggggtct tgatgacaat
     6481 ttcagtctcc tctaaattgc cgtcaatctc aattcgtaac ttcatcacat ctcctttctg
     6541 actctactat atcaaagcta agttaggaat acaagggcaa aaaagcaagt ggtcaatttg
     6601 aagcagtaag tggttgtagg actagcttaa cttacatgtc agaataggaa gaaaaggaat
     6661 ccccacacca aaccacaagc atagccaacc aagacatcct tgggataatg aacaccccct
     6721 aaaaccctca ccaaccccag caaagctgaa aagatcaagc atactaagcc aataggtaga
     6781 ctagcatgca gacaggccat ggagatgata gttgccgaaa agacatggcg actgggcatc
     6841 gaccgtcccg aactatcctt atcaagaagg ggacagatat cccaagtttc ataaggtctc
     6901 gggtgattga ttttcttacg aaacagggac aaggtcacaa aacctgatgc aggaataagc
     6961 acataaaccc caacttgctg accaagtcct agttgcaggt aagtggtgac tagcaagatc
     7021 agatagacca gggacatggc gactgtcatc aaacgattga aactgcgtaa taggaataaa
     7081 agaattggac gactagttag tctggagctg atatttcgat accattcttg ataatttttc
     7141 atttatgctt ctcatacttt tctagaactt gttgagatgt tttccccttg gcaagccaat
     7201 ccactagctt gtccaagcga cgtatttcct gcatcagagg atcatcaatt tcctcaatac
     7261 ggacaccgca aatcttccct gtaattgcaa ttcgttcagg gacataatat ggtgcttgtc
     7321 taaaaaaatc tccgtaagta acatccctat ccagacaagc aagaacatca ctcacttcat
     7381 accctgtcaa ccaactggtc acttggtgaa ctgactctgc ctttccaccc tttcgctcaa
     7441 cttttgcaat caaggctaag tagacagcag caaatttcat attgtataat ttctgactca
     7501 tacttctctc tttctatgtg tactagtata aataagaaaa agaaggccgt caagccttct
     7561 tttgatttat tcttctgctt catcttctgt aaattgacta ttgtacaagt cagcgtagaa
     7621 gccaccttgc gccatcagtt cctcatagtt gccttgctcg atgatatttc catctttcat
     7681 gaccaagatc aagtctgcat ttcggatggt tgacaagcgg tgggcaatga caaaggatgt
     7741 gcgtcattcc atcaaacggt ccatggcttt ttggatcaat tcctctgtcc gtgtgtcaac
     7801 agaagaagtc gcctcatcca aaatcaaaag cggtgcatcc ttaagaaggg cacgagcaat
     7861 agtcaatagt tgtttttgtc ctacagacaa ggtcacggtg tcatccaaga tggtatcata
     7921 gccatctggc aaggtcataa taaagtggtg aattcccaca gccttactag cttccatcat
     7981 tcgttcatca ctaatcccta tttgattata gatgagattg tctcgaatag ttccttcaaa
     8041 gagccaggta tcctgcaaga ccattgaaaa ggcatcatgc acttctgaac gcgtcatagc
     8101 cttggtatcc acaccatcaa tgtgaatact tcccttatca atctcataga atttcatcaa
     8161 aagattgaca atggttgtct taccagtccc agtcggccca acaatggcaa ccttttgacc
     8221 agcatgagct gtcgcagaga agtcatagtc ttgaacattg acaccgtcca ccagaatttc
     8281 tcctgctgac acgtcgtaga aacgtggaat cagattgacc agagttgatt taccagaacc
     8341 tgttgaccca ataaaggcca ctgtttgacc agtttctgct ttaaagctaa catgttcaat
     8401 aactgcctcc gaatttgccg catagcggaa ggtcacatcc ttaaactcga cctgaccttt
     8461 gaagttttca tcagtcagct gcacttgaac agggttttgg atagaagaat gcaaatctaa
     8521 aacttgatta atccgcttag cagagaccat agttcgggga agaacgatga agagtgctcc
     8581 catgagaagg aagcccatga caacctacat ggcataagac atgaaaacaa tcatgtcact
     8641 aaagagaggc agacgcgcta tcgaagcagc gtcgttaatc acataggccc caatccagta
     8701 aatcgctaca ctcaaaccac ttgaaatccc catcatgata ggattcaaaa tagccataag
     8761 acggttgaca aacaaattca aacgggtcaa ttcatcattt actgctgcaa atttttcatt
     8821 ttgataatcc tctgcattgt aggcacgaac gacacgaata cctgttaaac tctcacgagt
     8881 gatactgttc agtttatctg tcaacccctg aatcaaggac tgttttggaa aggctagcgt
     8941 catcaaaacg gtcgtcatca ggacgttgac aatcactacc acaagtacgg cccagagtca
     9001 gtattctgaa tgacctaaaa tcttcccaat agcccagata gccataattg gaccacgcgt
     9061 taccacttgc aagcccatag taatcaacat ttgaacttga gtaatgtcat tggtagtacg
     9121 cgtcaagagg ctaggaattg aaaatttctt aatctctgtc tgcgagtaat ccaaaactcg
     9181 gttaaaaata tcacttctca gcctactagt ataagaagcc gccactcggg atgcaaaaaa
     9241 tccaactgca actacggaca agaaggcaag aaagagcatt cccatcatca tgcttgccgg
     9301 ctgccacaac tcatctaaat tagtttcttg actacctagc aaatccgtaa ttttcgagat
     9361 ataggtcggc acttccaact ctagatagac cgaaaagcaa gtaaagaaaa tggctagtaa
     9421 aatcatcccc cattcttttc tactaattct tttggttaat ttctttattc tctcctccta
     9481 ttcccttgat attttgcctg tagttgaccg agaactttct caaaaatcag taattcatct
     9541 tcatcaatgt cttccatcaa ctgcttgtct atgcgttcaa aaaaagcctt aacctgttgc
     9601 atctgagaac gtgctttgtc cgtcagacga acaaacttag cccgcttatc aacaggactc
     9661 gcctccaatt ccaccaaacc attttgcact atacgcttaa ccagattact agcaacagac
     9721 ttggtaatat tgagttcctg ctcgatatct ttaatcaaga ccaagtcttg gtttttctag
     9781 cgattatcca aaaaacgcac aacctgacct tgcggcccac ccataaattc aatgccgcaa
     9841 cgtttggctt ccttttgcac catcaggtga atttgatgac caaaacgctt aaagactaac
     9901 atcggtttat ccataatctc ccccttctaa ataaaaatag ttctctggag aataattaaa
     9961 tttctatgag aactattttc ttgattaaaa aaatcccaag tgattttctc acttaggatc
    10021 atgttctata ggttaaatta aaacccatct acgttcgtat aaatcttttg gacgtcttcg
    10081 tcgtcttcaa gaacgctgta aagtttttca aaggtttcaa ggtcttcgcc tgacaattcc
    10141 acttctgact gaggaatcat ttccaattca gtcacttgga attcttcaat accagactca
    10201 cggagagcaa cgatagcctt gtgaaggtca gttggcgctg tgtaaactgt gattgtacct
    10261 tcttgtgctt ctacgtcatc cacatccaca tccgcttcga gcaattgctc aaagactgcg
    10321 tctgcatctt cacctccaaa tacaataaca cctttgttgt caaagaggta agaaacagaa
    10381 cctgaagcgc ccatgtttcc gccgttttta ccaaaggctg cacggacatt ggctgctgta
    10441 cggttgacgt tagaagtcaa agtatccaca attagcatag agccatttgg cccaaaacct
    10501 tcgtaacgtc cttctgtaaa ggtttcgtct gtgtttcctt tggctttatc aatcgcttta
    10561 tcgataatgt gttttggcac ttgggcttgt ttagcacggt cgataacgaa tttcaaagct
    10621 gagtttgatt ctggatctgg atcacctttt ttagctgcta catagatttc tacaccaaat
    10681 tttgcatata ccttagagtt agctccatct ttagccgttt tcttggctac gatattggcc
    10741 catttacgtc ccattaggaa tctccttttt tcacatttta atctttatta ttataacaca
    10801 agtttttttg attttcacta gaggaaatgg attttattag caaatcaagc taggatagca
    10861 ctttacctgc taagatggtc ttacctttct atctttatca acagacactc atccacattc
    10921 aaaaaacaaa ctagaccatt atctgcaaat agaaagtttc agccaagttt gacaaagtca
    10981 gctcaaatta ctgtttgaag tttgtagata taagcgacaa aaacaatcat actgcacctt
    11041 ttgttgacag tctactccag acatatcata gttcaagtaa atactttgaa attcaacagt
    11101 tcttataggc gctattgtat tctaagaaat caatagaaga gtttctaagc aaacctctaa
    11161 tactcaataa aaatcaaaga gcaaaccaga aagctagccg caggttgctc aaaacactgt
    11221 tttgaggttg cggatggggc tgacatggtt tgaagagatt ttcgaagagt ataatttacg
    11281 tgttcccaag atggagaagt tagactagta cactggcact tctaaaccat tgctagcaat
    11341 tgatttgttc atatttaatt tcattttttc cataaatggg tattagatat aaacagcaaa
    11401 atatttccga tacgtgtcgt tcttgaattt ccaatcatct aaaacaagta aaggataatc
    11461 aatcccctgt atatcaagga attggctacc ctttttactt ttttacacat tctgtttgat
    11521 agattcattt taacatcacg agcatactcc aatggaaatc gctaggcaag agataaactt
    11581 tcagatatcc gcagagagat catcgcctct ttttgtcgca agcattctcc tctcctagtc
    11641 attttctacc ttatcttcta cctgaggata gagagttgtt ccccaaatag aaatcgtccg
    11701 cttacgcact agtggcaaat cggttttttc ataaaccgta cgccaccatt cccaggcaag
    11761 cccggtacac tctctaattt tgacagagag attacgaaca ttccctttta aaggaatact
    11821 agtggtaaag tgagccgtta aatcctgccc atttctgtcc caagccttag gagtcaagac
    11881 ttccttacct tgatgatcat aggataattc attccaagta atataatatt gggcaacata
    11941 ggcaccacta tgatccagca gtaaatctcc gtttctgtaa gctgtaacct tagtctcaac
    12001 atagtctgta ctattttgaa aggtcgcaac tacattgtca cgtaaaaaag aagttgtata
    12061 ggaaatcggc aagcctggat gatctgctgt aaagcgactg ccttcttgaa tcaagtcctc
    12121 taccatatcc accttgcctg ttacaactcg ggcacccgaa cttgggtcgc cccctaaaat
    12181 aaccgccttc acttctgtat tgtccaaaat ctgtttccac tctgtctgag gagctacctt
    12241 gactcctttt atcaaagctt caaaagcagc ctctacttca tcactcttac tcgtggtttc
    12301 caacttgaga tagacttggc gcccataagc aacactcgaa atatagacca aaggacgctc
    12361 tgcagaaatt cctctctgtt ttaaatcctc taccgttaca gtatcttgaa acacatctcc
    12421 tggattttta acagcatcta cgctgactgt ataataaatc tgcttaaaat taacaatctg
    12481 aatctgcttt tcgcccgaat ggacagagtt aaaatcaata tcaagagaat tccctgtctt
    12541 ttcaaagtca gaaccaaact tgaccttgag ttgttccatg ctgtgagccg tgattttttc
    12601 atactgcatt ctagctggga cattattgac ctgaccataa tcttgatgcc acttagccaa
    12661 caaatcgttt accgctccgc gaacacttga attgctgggg tcttccactt ggagaaagct
    12721 atcgctactt gccaaaccag gcaaatcaat actataagtc atcggagcac gatcgaccgc
    12781 aagaagagtg ggattattct ctaacaaggt ctcatccact acgagaagtg ctccaggata
    12841 gaggcgactg tcgttggtag ctgttacaga aatatcactt gtatttgtcg acaagctccg
    12901 cttctttctt tcgataacaa caaactcatc gggtagctga ttaccctctt tgatgaaacg
    12961 attttcaata ctttctccct gatgggtcaa gagtttcttt ttatcgtaat tcatagctag
    13021 tataaagtca tttactgctt tatttgccat cttctacctc ctaataagtt cctggattga
    13081 gttgcataaa ctcagacttg ttcagcgaaa tcagccgtgg ttggactaag taatccaaaa
    13141 tttcctcgta caattcttct gagacattgc gtcgccgtct ggctagataa gaagtcggaa
    13201 tgcccgtatt atccaacata aataccttat ctaagtcaat caaggttggt cttgtaaaag
    13261 gattacgagc tagatccggc tcttctatca taaagttctt gaccaaacgt ctggtcaaga
    13321 gagctggttt gaaggtctga tttttaacca actctttgtt tttagtcatg ctgttgtcaa
    13381 tacagatata catatgattc ttcacagcca aatcgctact aatagtcgga aaaggcaaat
    13441 aaagagctac aacatctcct ctcttaatca agcaagagca cccccttttc tcctaatgta
    13501 acatagacag gattgaccaa gtcttctgat tgactcagaa tttccaaagt ttgagtttgg
    13561 cgcgctgtca atttagtagc atcttgtctc ttcaatacaa aatgcttgtc gccaataacc
    13621 ttgacaatat aatccttctc caaagctgac tggtaaatcc acatcagatg ttgtctgtcc
    13681 tgagaactca agagagaagg attttcaagc ctcccgatag tctgataaaa atcaaaaaca
    13741 ggagctaact cctgccaatc tgattggcta gttgtcaagg ctagaaaaag ggctttgcga
    13801 gctgatactt cttggttagc cttgagagtt actttcccct ccaagttttt tagaaatcgg
    13861 gaaactccag aaagcaaatt tttctctaac tgcgagaaat aaaaaccttt cgttcccaga
    13921 cataagtctt tcatgtcgct ttctctagca aataagagct caaacatttg atagtaaaag
    13981 aaaaatatct ggcactgggt cgcgctcatc ttttccttat cggcttcttt ttttaaccag
    14041 agcaagggcg acaggtaact ggattgagac atttcctcta cctcctactc ttttttaact
    14101 ggagcatctg cactagctgc cacttctttt gactggatac tttcccactg gttaatctcc
    14161 tctgagataa gaccttcgca tgtcttgaca aatagggcaa aagccttggt ctttcctgca
    14221 tatttctccg tttggcattg atagaggaat ttttctttct ccaggagttg cgcagttttt
    14281 tggtaagaaa tccaattttc ctttgcatta tacaaattga taatcccctc acacagcaag
    14341 ccgagactgg ataaggcaac cgaaatcaaa cggtagcgat cacctggcat aggaatagca
    14401 caaaagacag ctatgaggaa acctgccacg atttctgtta tttttaatac cttatagcgc
    14461 ctacgatgtt gaacgctttt ctttaaaaaa tgagctatct gtacgtctaa tcgctctgtc
    14521 aggtacattt cttctggcgt catattcgta actcctttca tttactttga taaccatagt
    14581 ataacatatt tgaatatcaa agtatagtaa aaactggact ataacttatt agacttcctg
    14641 cgaaacaaaa tatggtatag tagttctatg aattatgaag caagtaaaca actaactgat
    14701 gcacgattta agcgtcttgt tagtgttcag cgtaccactt ttaaagagat gttagctgta
    14761 ttaaaaacag cttatcaaaa aagtcggaca agctggtaaa atcttggctg acagtggtta
    14821 tcaagggctc atg
//
LOCUS       DBEJJV010000047        14074 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.047, whole genome shotgun sequence.
ACCESSION   DBEJJV010000047 DBEJJV010000000
VERSION     DBEJJV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 14074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.047"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            83..880
                     /locus_tag="ACL3GT_001792"
     CDS             83..880
                     /locus_tag="ACL3GT_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HGR0517411.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLIHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="ACL3GT_001793"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="ACL3GT_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
     gene            2383..3657
                     /locus_tag="ACL3GT_001794"
     CDS             2383..3657
                     /locus_tag="ACL3GT_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HGR0517412.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELCLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="ACL3GT_001795"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="ACL3GT_001795"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HGR0517413.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALSLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="ACL3GT_001796"
     CDS             4786..5088
                     /locus_tag="ACL3GT_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HGR0517414.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="ACL3GT_001797"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="ACL3GT_001797"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HGR0517415.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /gene="xseA"
                     /locus_tag="ACL3GT_001798"
     CDS             5962..7302
                     /gene="xseA"
                     /locus_tag="ACL3GT_001798"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HGR0517416.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESIVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="ACL3GT_001799"
     CDS             7280..7492
                     /locus_tag="ACL3GT_001799"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HGR0517417.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="ACL3GT_001800"
     CDS             7489..8364
                     /locus_tag="ACL3GT_001800"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HGR0517418.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQIIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="ACL3GT_001801"
     CDS             8357..9172
                     /locus_tag="ACL3GT_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HGR0517419.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQIFAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="ACL3GT_001802"
     CDS             9165..9596
                     /locus_tag="ACL3GT_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0517420.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="ACL3GT_001803"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="ACL3GT_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HGR0517421.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKERIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="ACL3GT_001804"
     CDS             11272..12000
                     /locus_tag="ACL3GT_001804"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HGR0517422.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="ACL3GT_001805"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="ACL3GT_001805"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HGR0517423.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT         4160 a         2561 c         3355 g         3998 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg atacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa acctcttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gccttggctg agaaatactt gccaaaagat gtcggttcaa tctttacctt
     2041 ccatgtcaaa ggtggcgagg aagaagcacg caaggtcatt gatcatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caaccactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaact aaattcgttt
     2221 gtcaatcggt cttgaaaatg tagaagattt gattgaagac ttgcgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg cttcgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaaa gaagtctaga aagaggaacg atatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gagagtcagt atgccgaact cttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaagcagga actggccttg
     2521 gctgagcaaa aggccatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatgtttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataaggattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcagac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggccgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagccacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc agttgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagacttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gatcatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttt ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaatcggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgta ttattcgtcg tatcaagcgt gatatggagg
     5641 aacgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat aaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaaatat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctaccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatcctac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattaactca tttgcaaaat
     6781 caggaaaaac ggatggcaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccattgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttacca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagattaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctttg
     7981 gaagaacttc agattattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ctgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattagaag aaattgccca gcagcttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtaatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgacaccg aattaaaact
     8521 caagggagag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gttagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcat cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agatttttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgatacttt tgcagacaag atttttagtt gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gaacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctga
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cattttagta
    10801 agggaaaatt cagtcgtggg ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagcatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcgtcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatatttgt tcacgcaggt
    11701 attgatttga ctttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacaggg gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac gggaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagag cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga tctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaatcgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagtt ttgactacga attgtcagaa tatcgcccat ctaagctagt gaaaatggat
    13561 atccttctca acggagacaa ggtggatgcc ctcagcttta tcgttcataa ggactttgct
    13621 tatgaacgtg ggaaactcat cgttgataag ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaggttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaa
//
LOCUS       DBEJJV010000048        13957 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.048, whole genome shotgun sequence.
ACCESSION   DBEJJV010000048 DBEJJV010000000
VERSION     DBEJJV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.048"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..262)
                     /locus_tag="ACL3GT_001806"
                     /pseudo
     CDS             complement(1..262)
                     /locus_tag="ACL3GT_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(324..773)
                     /locus_tag="ACL3GT_001807"
     CDS             complement(324..773)
                     /locus_tag="ACL3GT_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0517424.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(775..1533)
                     /locus_tag="ACL3GT_001808"
     CDS             complement(775..1533)
                     /locus_tag="ACL3GT_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HGR0517425.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAKPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1648..3627)
                     /gene="stkP"
                     /locus_tag="ACL3GT_001809"
     CDS             complement(1648..3627)
                     /gene="stkP"
                     /locus_tag="ACL3GT_001809"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine-protein kinase StkP"
                     /protein_id="HGR0517426.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3624..4364)
                     /locus_tag="ACL3GT_001810"
     CDS             complement(3624..4364)
                     /locus_tag="ACL3GT_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HGR0517427.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(4379..5692)
                     /gene="rsmB"
                     /locus_tag="ACL3GT_001811"
     CDS             complement(4379..5692)
                     /gene="rsmB"
                     /locus_tag="ACL3GT_001811"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HGR0517428.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5685..6620)
                     /gene="fmt"
                     /locus_tag="ACL3GT_001812"
     CDS             complement(5685..6620)
                     /gene="fmt"
                     /locus_tag="ACL3GT_001812"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HGR0517429.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHAFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6633..9029)
                     /locus_tag="ACL3GT_001813"
     CDS             complement(6633..9029)
                     /locus_tag="ACL3GT_001813"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HGR0517430.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEVAYK
                     QDSNPRYHARDVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9095..9409)
                     /gene="rpoZ"
                     /locus_tag="ACL3GT_001814"
     CDS             complement(9095..9409)
                     /gene="rpoZ"
                     /locus_tag="ACL3GT_001814"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HGR0517431.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9434..10060)
                     /gene="gmk"
                     /locus_tag="ACL3GT_001815"
     CDS             complement(9434..10060)
                     /gene="gmk"
                     /locus_tag="ACL3GT_001815"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HGR0517432.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10190..11803)
                     /locus_tag="ACL3GT_001816"
     CDS             complement(10190..11803)
                     /locus_tag="ACL3GT_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HGR0517433.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11885..12154)
                     /locus_tag="ACL3GT_001817"
                     /pseudo
     CDS             complement(11885..12154)
                     /locus_tag="ACL3GT_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004027196.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(12286..13044)
                     /locus_tag="ACL3GT_001818"
     CDS             complement(12286..13044)
                     /locus_tag="ACL3GT_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517434.1"
                     /translation="MKFKNYLFDLYPYFPKGFSLDNREDPDVCSKALYDDLCKMFFDD
                     DSKEKLKITSVCNKCQNYGNRDYYTLFIDKDKYLLSSDYIGASIYWAQEAGLNDRIIL
                     DHLSISRTIGGHILFPRGGKLETVNQARGGEKGYYDRFDLTLYAIKEWFVENKNTKIG
                     YAIENYHEWFELFSGDDNCKNGFENFVEFFKLEGFIYEQNKIIDLIKSDLENNQVVFL
                     DKEDILIASTEEEYIRYMKNLNIIILERTKKILL"
     gene            complement(13060..13200)
                     /locus_tag="ACL3GT_001819"
     CDS             complement(13060..13200)
                     /locus_tag="ACL3GT_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517435.1"
                     /translation="MLFYLTKELNSGVKKIGTISTTLVVVAGVSAGVLGGKFDFKFPK
                     KI"
     gene            complement(13154..13657)
                     /locus_tag="ACL3GT_001820"
                     /pseudo
     CDS             complement(13154..13657)
                     /locus_tag="ACL3GT_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370715.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_component: GO:0005634 - nucleus [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
BASE COUNT         3833 a         3250 c         2599 g         4275 t
ORIGIN      
        1 cttgtgacaa tcgcttgagc cttcatagcg tgaaatttct ttttaccaga atcattcgct
       61 aattgttttt ttaggacaat tgatttgtac ttccgtcgca tcaatcatta ccgtgtcttc
      121 agaactgaga ggagttcttg aaatcgtaac accacctttg aacaagagtt acttcaaccc
      181 attggctccg acggagtaag ttgctttcgt ggataccaaa atcagccgca atttcttcat
      241 aagtgcggta ttctcgcaca tatagaaagc gttgttaatt tatttatctc atttttcaga
      301 aaattctttt atttctgtaa agtctacgat actcgatgtg tttttatata atgatacagt
      361 ctgagaatca ctgttccgct agccattcca atagagatta ccaaagccaa catgacaacc
      421 aaggtcgcac ttgccagtgc tttattatag tcccctgtca caaaaaaggc agttgttcgg
      481 taggagagat aacctggaac cagcggtgcc aaaatggcca agataaagac cacagcaggt
      541 gtcttataaa gaatacttaa aatctggctg acacaagaac caataatggc tgcaatgaag
      601 gtagctacaa tgacattggt cggttccttg agcaagagat agattagcca gacagtcatg
      661 cccaaaatcc ctccaggtaa gagcatagac cgttgcacat tgagtacgat taaaaaagtg
      721 ataatggcaa gaaaacttgc tactgcttgt aataaaaagg ttgttagtgt catattagtt
      781 catcaatacc aaggcgacag aagttcctgc ccctaaagcg agggtaatga gcagggattc
      841 aaacatctta ctcataccag agtttatgtg gttggtcata atatcacgga ccgcattggt
      901 caaggcaata cctggtacaa acggcatgac cgcaccagct ataatcaaat ctgccgttga
      961 aggaaaacct gtgtagcgag cccaaaactg ggcaattatc ccaaagacaa aggctccagc
     1021 aaaggctgtc acaaagggaa ttcggataaa tttttccaca tagagggaaa aggcaaaacc
     1081 aaataaggtc gccactcctg ccccaagtgc gtcgtagata tttccgctaa acataactga
     1141 aaagaaagga gcactaaagg tcgcagccag agttacctgc aacttagtat agggaagggg
     1201 tttggcttgc aaggccgtca attgcttaaa ggctgtttct aagtcaatct gccccccaac
     1261 tagctgacga gaaatctggt tcacatcgca gactttttcg atgttataag aagaggaggt
     1321 cacgcgcttc atgcgcgaaa tattggtatt ttcaatagag aaaaagatag cggcaggcat
     1381 ggcaaggaca ttgcaatcca caatcccctg cgaatgcgcg attcgaatca tggtatcttc
     1441 tacacgatgg atttctgagc cacttttaag gagaatagtc cccgctagca taatcacatc
     1501 aatgacggca tttaattctt ttgattcttc catgctttcc tccttttatc aactccctct
     1561 attctatcac aaatccggac tcaaaaaaaa tctttgccat gaaatcatga caaagattga
     1621 ttactcattt tgattatcca tctgctttta aggagtagct gaagttgttt taggtttgta
     1681 gattgaaatc ttgactctag tcttatttag gtctaccttt tcacctgctc taggactttg
     1741 ttcaacaacc atgccttcta cactacctgc aggcgctgtc gtcacttcta caacttctat
     1801 attagcttcc ttaatcccaa caatttgaat caaattgttc ttagtaaact ccaagctgga
     1861 accaatgtaa ctcggcatgg caacacttgt aactttttta gctactgtca agacaatttg
     1921 agtaggttta ctcacatcat aagtcgttcc ggcacctgga ctttgtttca taatcgttcc
     1981 tggttcgctt tcgctggact cttcttcctc tatcttaatc aaattctcag gaaccttctt
     2041 ctgcttgagt tctgagatta cttctgtaga gttccgtcca atatagttcc ctaattgaat
     2101 cgtcgtagct tttttagcta ctgtcaaaac aatttgagtt gccttgctca agtcataggt
     2161 cgtaccttct ggtagacttt gcttcaagac cgttccagcc tcactctcat tggactcttc
     2221 ttcctcaatt ttaatcaaat tatctggaac ttttttctct tttaattccg cgataacatc
     2281 agaagatttc cggccgacat aattactaat ttggaaggat tgtttgcctg atgagacaac
     2341 cagattgatt ttcgttcctt cttttcgacc agttccagcg ccaggatctg tacggataat
     2401 ccgcccttct tccacctttt cactagcctc tgtcttctcc tcaccaatct caaaattggc
     2461 ttttttgagc gttgccttgg cctctgcaac tgtctgacct gccacatccg gaatggcaat
     2521 ggttgcagga gttctggata agatccaaat aagagaagct gccaccaata caaggctggc
     2581 caacaaaatc aggtaacgca tcttaaatct atgttttttc ggtgcttgtg gttggtaagt
     2641 ttcctctgtc acagcctggc ttgggttttt gattgatttg tgttctgtct gcgcttgaac
     2701 cttaggaata gatgtcaagg tactctgaga aaccttcggc aaggtcttgg tatctgcctt
     2761 gctcgtttca tcaaagatta acttactttc atttctacga ttgtaggaca agctactaga
     2821 caagtccaca tacatctctg aaaccgatcg gtagcgattg gtcaactttt tagcagttgc
     2881 cttgataata acattttcta aagcctgagg tacagatgga ttttctgcaa taacggacgg
     2941 caggggtttc tggaaatgct ggagggcaat ggtcaccgcg ctatccccgt cataagggat
     3001 atggcctgtc aacatctcat agaaaataat ccccatggca tagatatcac tctgcacagt
     3061 cgccttagaa ccacgcgcct gctctggtga caagtaatga actgagccca acatcgagtt
     3121 agtctgggtc agacttgtct ctgcaaaggc tacagcaatc ccaaagtctg tgaccttggc
     3181 agtcccatct ggtgtcaaaa ggatattttg aggtttcaag tccctgtgaa caattcctcg
     3241 agtatgggcc aagcgcatag ccaagagaat ttgtcccatg atacggacgg cttcttcatt
     3301 agaaagagga taatgttcct tgatatagcg tttgaggtct agtccagcaa catactccat
     3361 tgcaagatac tgttgaccgt cttcctcacc aatatctgtt atccgaacga tatgaggatg
     3421 gtctagatct gccatagctc tcgcttcacg ctgaaaacga gctacagcta tcgggtccgt
     3481 ctggtagttg gtcctcagaa ccttcactgc cacttcttcc ccatctaaga ttaagtcttt
     3541 ggctaggtaa acatccgcca tgcctcctcg accaatctgt ttgacaatcc gatagcgtcc
     3601 ggcaaaaatc ttgccgattt ggatcattct tcatcctcct cgttcataga aacaagggca
     3661 accgtaatgt tgtctaaacc tcctgcattg ttagcaaaac gaacaagtgt ctccgtttta
     3721 tctgctaaag gaatatcact ggttacaata tcacgaatct cactgcctga aatcatgttg
     3781 gtcaagccgt cactattgag caagagatag tcacctgact caaggataac tgtcccaaaa
     3841 tcaggctgaa tttcatcttt ttgcccaata gactgggtga taatattttt ttgcggatga
     3901 gcttctgcct cttctggtgt caattgacca gccttgagca attcattaac caaggaatga
     3961 tcgctcgtca actgatggta ttcttctcca cgaatcaagc cgatacgcga atcaccaata
     4021 tgagcataga tagcctgatt atcaataata gcaaggactt ccaaagtagt tcccatgcct
     4081 ctgtaagctt catcctgacc aagctggtga atcttttgat tttcaatttc taggtaatgg
     4141 gcgaaccatt cacgcacttc attgactgta tcgatctggg tatcaaccca agctacaccc
     4201 aggtctgtga ccgccatttc actagcgata ttccctgcac gatgacctcc catcccatca
     4261 gctaaaataa tcatggtacg tccagctcta ttgacatagt ggttgacata gtcttggtta
     4321 tttgttcgtt tctgaccaac atctgttaat aatgaaattt ccatgtgtca gttccttcct
     4381 aatccgatat cttgcgaaat tgactgatga agaatccatc acttccatac aattcaggtg
     4441 taatgaggat acagccgtct ttcatgatat ccttacattc atgttctagt tttacctgct
     4501 cgaactcggg atgactctct aaaaaggcct taacgacttg aaaattctcc tctgagacga
     4561 tagtgcaggt gctataagtt attataccac ctttgcctag tatttgacaa acactaccta
     4621 atatttctaa ctgaatttcc tgcaaggacg cgaaatctgc cgtttcttta ttgtatttga
     4681 tatctggttt tcggcgcaaa agaccgattc ctgaacaagg agcatccacc aaaatcttat
     4741 caaaggaatc ctggtcaaaa aactcatgca cctttctggc atccaatttt tgagtttgaa
     4801 cccgatcttc aactcccaga cgttgggcat tttcttgaat taaatccaac ttgtggtcgt
     4861 acaagtccag agcagtaacc tgacctgtcg taagataaga ggctatatgg gctgttttcc
     4921 cacctggagc cgcacaggca tcaagcactc gctcatcacc ttgtaaatca agcgtcggag
     4981 caaccagctg actggactcg tcttggatgg taatggctcc atccgcaaac aaattatgcc
     5041 ctgcaaaatg cccctgctcc ttaaccagac cagtggttgc taaaagggaa tcattcgcct
     5101 ccaacaaggc ttggatttcc tcttttcgac ttaggtctgt tacacgaata ctggctttgt
     5161 ttcgcactaa caggctttca aagatggctt ttgctctctc ctctccgtat tcttccttga
     5221 gtttggcaac tagccaaact gggagagaat aggcaatgga gtcacgcttg ttttttcgct
     5281 tgatgctagc aatatctggc cagccttcac gcaagatacg gcgaaggagg gcattgacca
     5341 atttttcact gcctttttta cgaagtttgg ccaattccac tgcttcattg accacagcat
     5401 gatctggaat cttgtccaaa tagcggagtt ggtaggcact catgagaaga aggacataga
     5461 gccagctgtc taactggtct ctgtcttcga taaagtggga taggtaccat tccagagtca
     5521 gtttacgggc taccgttcca tagaccagct cggtcactaa gcccttgtct gctgccaaaa
     5581 gttgactccc ctttagatgc ttatttaagg cgatatttga gtatgcttgg ttcacaaaaa
     5641 catcctctag cactgctaga gctaaacttc tagccgtttc tactttagtc accaaatcgt
     5701 tctcctacag tcaatgtacg tccaactccg ttgaggaagg aagcaatgtc catcttaggc
     5761 ttaccagctg gctgcacttg tttgagggat agagcccctt cagccgttgc gacaatcaat
     5821 tctttcttgc cgatagagag aatctcacct ggatttccct gaccttctac tggtagggct
     5881 tcataaatct taaagcggtc gcccttaagg aaagcatggg caacaggcca ggggttcatt
     5941 ccacgaattt ggttaaagag ttgacgattg gttttgttcc agtccagttt ttcttcctct
     6001 ggctttatat ttggagagaa ggtaacctga ctcgtatcct gcggttcagg tttgatatca
     6061 ccagcaatat aggcaggcag agtgtccaaa agcaaatcac gaccaactag cgccaatttt
     6121 tcaaacaagg tgccaacatt gtcctcatct gtgatcggaa tgctgcgacg agaaatcata
     6181 tctcctgcat ccatttcctt aaccatttcc atgatggtca caccagcttc ctcatcccct
     6241 tgaatcaagg cataatggat aggcgcacca ccacggtgtc taggaaggag ggaggcatga
     6301 acgttgacag caaagtccat gctatcaagg agtttgcttg ggagaaactg cccaaaagca
     6361 gcagtcacaa ttccatctgc tcctagcttc ataagttctt ccatctctgg acttccagat
     6421 aatttttcag gttggtagat agatagtcct gcttccttgg cagcctgctt gactggggtt
     6481 tcttggataa cttttttacg accaacagca cggtctggct gggtcacaac ggctagaatt
     6541 tcgtaacggt catctgtcaa aagtcctttt aagactgttg ctgaaaagtc gggggtcccc
     6601 ataaagatta gttttgtcat atcttctcct tcttataaaa attgctgcgg ctcatggtca
     6661 atgctgagac ggagctcact attttcccgt tcttgagtca aggccaagac ctggttgagg
     6721 gtcggcccca gctcatcttc taaacggtat ttaattaaaa tctggtaatg atagaggttg
     6781 tgggtacggg caatcggttt tggcgttggc cccagaatgg gactggtctc tgacaagcct
     6841 gaccgcaaaa tgttcatgac ttcataggca cgtttgaaaa cctcttcttc tttcttgtga
     6901 gaaagggtaa taccaatcgt gaaatagtaa ggtggatagc cgagttgtcg tctgattccc
     6961 atttcatagg cataaaagcc ttcgtaatct tgatccttgg caaatcgaat agcatagtgc
     7021 tgcgaattgt aggactgtat caagacttga cctgcttttt cagcccgacc tgctcgacct
     7081 gccacctgag tcaagagctg gaaggttctc tcagaagaac ggaaatcagg cagattcaag
     7141 gccgtatccg catttagaac tccgactagg gtaacattgg gaaaatccaa accctttgca
     7201 atcatctgag taccaagtaa aatatccgct tcccctcgcc caaactggtc aagcaaggct
     7261 tggtgactgc ctttctttcg agtcgtatcc acatccatcc tcaaaatgcg agcttgggga
     7321 aagagttctg ctagctcatc ataagccttc tgagttcccg tcccatagta acgaatactg
     7381 cggctcttac agttaggaca gacctgagga atatccttcg agaaaccaca ataatggcag
     7441 ttcatagtct tggtatccat atgcaaggtc agagaaatat cgcagttggg acaagtatcc
     7501 accgtcccac actcccgaca catgacaaag ctagaataac cacggcgatt gagcatgaga
     7561 accacctgct cttttttaac cagacggtct tggatagcct ctagcaaagg aggcgtaaag
     7621 tttgacgtct cattttgtcc gatatagtct cgaaagtcaa tcacttgaac ctcagggatt
     7681 gtagccaaag gattagcacg ttgggttaga cgtaagtgtt gatagacgcc tttgccagca
     7741 cgtgcccggc tctctaagct cggcgttgca gatccaagta ccagagttgc ttgattatac
     7801 tgagcccgta aaatagctac atctctggca tggtaacggg gattgctgtc ctgcttataa
     7861 gccacttcat gctcttcatc aataatcatg acacccagat ttttcagagg agcaaagata
     7921 gcagatctgg caccaacaac aacttgggca tcgccacgct ccaccttgcg ccattcatca
     7981 tacttttcac cattggataa tcctgagtga agaatggcta ccttgtcccc aaaacgtgct
     8041 ataaaacgct cggtcatctg aggagtcaag gaaatctcag gtaccagcaa aatagctgtc
     8101 ttgcccttat ccagggcacc ttggataatc tgcaagtaaa cctcggtctt cccacttcct
     8161 gtaatccctt gaagtagaaa gggaggttga gaactgccaa tagaactcac aaccgcatca
     8221 cgcgcctgtc tttgttctgg atttaactcc aaaggtctac ttgcttcaat tccttcaaaa
     8281 taagcagccg agcgttgaac ttccttttgg actatggtaa cagcaccttg atccacaaag
     8341 aagttgactt gctctcgcga gtaggactct aacaagctag ccaaggaagc gctctctgga
     8401 tgagacagca gataatctct cagttccaac tttttcttgg cacgtgtaga aatctcaaca
     8461 ccttctaatt gagcatggtc aacctcatac caagactggg tcttgacctt cttttgatcg
     8521 actgcctgat attccagacc aagcaggcct tttctagtca aacgcatcat ttcagcttgc
     8581 ttggcaaggt ctagtgaaga aaaggctagc gaatcttctg aaccaaacag gcgcactcgt
     8641 tcttcctgac tcaagccttc cagaggatag agaatcttgt catagctaga attcagaaat
     8701 cctggaagca tggccttgag gatagaaatt ttgtaggaga agacagattt gcgtaactcc
     8761 tcagccagcc agagttgttc tggcgtgaga acaggagaaa aatccagcac ctctgcaata
     8821 tcttttaaat cttgctccat ctcttctcca tctgattggg actccaaacc aagaacaatc
     8881 ccttgaatca ggcgattccc cttaccaaaa ggcacatgaa cccgcatccc aacttccagc
     8941 attccctcaa attcctccgg aatcctgtaa ctatagggct ggtccgtctg catcaagggc
     9001 acatctacga taatcttagc tagggccatc gtctcacctc ctccttgtca gtacattctt
     9061 gcaatagaaa aaataagatt gagtcccccc aaccttaaat tttttcacca tcttcttttt
     9121 ctttagcaat ttgctctttg attttctttt cttcttcttc tttgcggcgt ttttcttctt
     9181 cgatacggcg acgcactgct tcacgttttc cttctggatc tgggtgaatt gtaacgtttc
     9241 ctgattcgat ttcttctaaa gcgcgaagag ttgatttttc agacttaaaa ccttgagttg
     9301 ctggggcacc tgcttccaat tcgtgggcac gttttgcttc caagattacg agtgaatatt
     9361 ttgaaggaac cttgtcgagc aaggtatcaa tagagggttt taacatcatt tgcttgtacc
     9421 tattttctaa attttatcgg gtagttggag attttggtaa catctcctga tagtgaccaa
     9481 tgacacgatc cacacagaag tgttctgctt caatcacaca tttgacacgt tcagcagcta
     9541 ggggtacctg atcgttgaca atcgcataat catactcacg catgagggca atttcttcct
     9601 tggccttttc gattcgttgg gcaatcactt ctgcactatc tgttccacga cctaccaagc
     9661 gatcttgcaa ttcatccaaa tctggtggtg tcaggaagat aaagacagca tctggaacct
     9721 ttttcttgac ctgaagagca ccctgaactt caatttcaag gaaaacatcg attcccttgt
     9781 ccaaggtttc attgacatag gtcagaggag ttccatagta gttgccgaca tattctgcgt
     9841 attccaacat ctgtccttga cgaatcagct cttcaaattc ttcacgagta cggaagaaat
     9901 agtcaacacc gtccacttct ccaggacgtt gtgcgcgtgt cgtcatcgat acagaatatt
     9961 gaaattggtt ttcagaactc tcaaaaatct ctcttctaac cgttcctttt ccaacccctg
    10021 aaggaccaga aaaaacgatt agtaagcctc ggtctgccat tgtgtctcct tttagtcaat
    10081 ctgtgaaata acatttctct agaataatgg caaaaagcca gattatcctt tacagtcttt
    10141 ctatctagtg taacaaaaaa gcagtaattt ttcaactgct ctttcttatt tatttagcat
    10201 aatctactgc acgaagctcg cgaatcacgg ttaccttgat atttcctgga taatcgagat
    10261 tgttttcaat tttcttacga actttgtgag ccaagattgt gactttgtcg tccttgattt
    10321 ttcctggatt gaccatgata cgaatttcac gtcctgcttg aagggcaaag ctagtttgca
    10381 ctccttcaaa gccgttagca atttcttcca aatcatggag acgcttgatg tagctttcaa
    10441 gagactcact acgagcacct ggacgggctg cgctcaaggc atctgctgca gcgacgataa
    10501 ctgctatcac gctctcagct tcaacatctc cgtggtgact agcaatcgta ttcaccacaa
    10561 ctgggggttc cttgtactta cgggccaatt ccataccgat ttcaacgtgg ctaccttcaa
    10621 cctcatggtc aatggctttc ccgatatcgt gaaggaatcc agcacgacgg gcaagagccg
    10681 cattttcacc aagttcgctc gccatgatac cagccaactt agcaacctca atcgaatggc
    10741 gcaaaacatt ttgtccatat gaagtacgga actgcaaacg tcccataatc ttcatcaagt
    10801 ctggatgaag gtttggcgca ccaatttcat aggcagcagc ctcaccgtat tcacgaatct
    10861 tattgtcaat ctcttgacgg tttttctcaa ccaactcttc gatacgagct ggatgtatac
    10921 gaccatcttt gagcaacatt tccatagtca tacgggcaat ctcacgacga atcggatcaa
    10981 atcctgacaa ggtcaccact tctggtgtat cgtcgataat cacatcgacc cctgtcaaac
    11041 tttcaaaggt acgaatgtta cgaccttcac gaccaataat gcgtcccttc atagtatcgt
    11101 ctggcagatg aactgttgag tttgttgact ccgctacata ttcaccagcg atacgttgca
    11161 tagcttgaac caagatgtcc ttggccattt tgtcagaacg ttccttgacc tcttgctcag
    11221 cttcgcgaat gcgactggca atctccctgg tcaagttttc ctctgtctga gccaagataa
    11281 tatctcgtgc ttctgcctga gacagagcac caatacgctc tagttctgct tctttttgtc
    11341 tttcgacttc ctctaattgc tcttcacgcg catcaaggtt tttcgctcta tcagaaatac
    11401 tttgttcttt ttgttcaagt gtttgttctt tactcgtcaa attgtcgtcc ttacggtcaa
    11461 ggctagtagc tctctctgtc aaacgacttt cgatttgttt gagttcttga cgttctgatt
    11521 tgaattcagc gtccacttct tcacggtatt ttctggcttc ttctttggcc tccaatagtg
    11581 cttctttttt aagagacttg ctttcacgtt tggcttcatt aacaagtaaa tccgcttcac
    11641 gctcagcttg tccacgtaaa ttagttgctt cttgttcagc atttaaaagc atcaactctg
    11701 cagcttcctg agatgatttc atcttagctg agatgctgac atatccaatg actaaaccaa
    11761 tgatgacggc aaaaacagca atcgcaagcg acatgatttc catgttttta cctcatttta
    11821 ttgttattcc gaatgacata cattctttta cattctacca taaaaaaaga atttaaacaa
    11881 accttaaatg gatatcgcta acatccgcat tatcactatc atagttatca tttacagata
    11941 taaagcgaat acctttttca ggaaatatct tttgtaagta ctttcctgac tcgatataat
    12001 ctctgccgaa acgagataaa tcttttacca taatgataga aaactttcct ttattcaggt
    12061 catcaatcat attcttaaaa tttggtcgct caaaattaga accactatat ccatcatcta
    12121 catattcata ggataattca atagatttct cttctacctc caaaaagcaa aaaggataaa
    12181 tttcccctac actttaatag tgaaaattta tccctcttgg taagctcttt tattaatttt
    12241 tttgataaag aaaacgcaca ttttatttaa ctggtgctga aatctttata ataaaatttt
    12301 tttggttctt tctagaataa tgatattaag atttttcata tatcttatat attcttcttc
    12361 tgtgctagca atcaaaatat cttctttatc taaaaagaca acctgattgt tctctaaatc
    12421 tgatttaatt aaatctataa ttttattttg ctcatatata aatccttcta acttgaaaaa
    12481 ctcgacaaag ttctcaaatc catttttaca attatcatca ccagaaaata gttcaaacca
    12541 ttcatggtaa ttctctatag cataacctat ttttgtattt ttattttcca caaaccattc
    12601 ttttatagca tatagtgtta aatcaaaacg atcataatat cctttttctc cacctctagc
    12661 ctgattaacg gtttctaatt ttccacctct agggaaaaga atgtgtccac ctattgttct
    12721 tgaaatactc aaatgatcta aaattattct gtcgtttaat cctgcctctt gtgcccaata
    12781 aatagaggct cctatataat cacttgataa taaatactta tccttatcaa taaataaagt
    12841 ataataatct ctatttccat agttttggca tttattacat acagatgtta ttttaagttt
    12901 ttcttttgaa tcatcatcaa aaaacatctt acataaatca tcgtacaacg ccttactaca
    12961 tacatcagga tcctctctat tatctaatga aaaacctttg ggaaaataag gatataaatc
    13021 aaatagataa tttttaaact tcatatttat tattctccat taaatctttt taggaaattt
    13081 aaagtcaaat tttcctccaa gcacacccgc acttactccc gcaactacta caagtgttgt
    13141 actaattgtt cctattttct tcacgccact gtttagctct tttgttaaat aaaacaacat
    13201 tgatcatatc tgcttcactt acatacttgt aagacaactg ttcgttggta agatctttta
    13261 agagatattc tttgattgca tctgtatgaa ttttgtagtt aatcttagaa atttctctat
    13321 tcaaattcca gcctaatgat agcttagaat tttaatctga cttaagtctt ttgtaatcct
    13381 gaattacata catcttaaat tcagcagaaa tacataaagc aaattcaaag gcaatatctg
    13441 tatgtgcaaa tgcaccacca tatcttccac cttttgagat aattccgatt gctccagttt
    13501 tctctaccca tttcttagga gacaatgtaa atgaattata tccagcttcc gatttaattc
    13561 ggtcgaattc gaccgaattg aaattcatgt tatttaagct tttccataaa ccaagaaact
    13621 caattgtatc ttttcttctc atccaatttt taattacatc actcgatact tatccgaacg
    13681 ataagctcca cgtaaggtgt tcgcaatcga ccaaactgca ttgactacat ttgaaatctg
    13741 aacatcgttc gactggaata tcggtagttt ttctttaaaa ttagacattt gcttcccctg
    13801 tttttatgat ttacaattct cttcattata ccacaaaata ggcgctttgt caactgtagt
    13861 gggttgaagt cagctaagct cgagaaagga caaatttcgt cctttctttt ttgatgttca
    13921 aagcgataaa aatccgtttt ttgaagtttt caaagtt
//
LOCUS       DBEJJV010000049        13906 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.049, whole genome shotgun sequence.
ACCESSION   DBEJJV010000049 DBEJJV010000000
VERSION     DBEJJV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13906
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.049"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..1088
                     /locus_tag="ACL3GT_001821"
                     /pseudo
     CDS             1..1088
                     /locus_tag="ACL3GT_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436408.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(1173..2375)
                     /gene="rpsA"
                     /locus_tag="ACL3GT_001822"
     CDS             complement(1173..2375)
                     /gene="rpsA"
                     /locus_tag="ACL3GT_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HGR0517436.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2537..2608)
                     /locus_tag="ACL3GT_001823"
     tRNA            complement(2537..2608)
                     /locus_tag="ACL3GT_001823"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2574..2576),aa:Gln,seq:ttg)
     gene            complement(2618..2698)
                     /locus_tag="ACL3GT_001824"
     tRNA            complement(2618..2698)
                     /locus_tag="ACL3GT_001824"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2662..2664),aa:Tyr,seq:gta)
     gene            complement(2748..2978)
                     /locus_tag="ACL3GT_001825"
     CDS             complement(2748..2978)
                     /locus_tag="ACL3GT_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HGR0517437.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3146..3790)
                     /gene="pcp"
                     /locus_tag="ACL3GT_001826"
     CDS             complement(3146..3790)
                     /gene="pcp"
                     /locus_tag="ACL3GT_001826"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HGR0517438.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3805..4728)
                     /locus_tag="ACL3GT_001827"
     CDS             complement(3805..4728)
                     /locus_tag="ACL3GT_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0859 family membrane protein"
                     /protein_id="HGR0517439.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4725..5414)
                     /locus_tag="ACL3GT_001828"
     CDS             complement(4725..5414)
                     /locus_tag="ACL3GT_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0858 family membrane protein"
                     /protein_id="HGR0517440.1"
                     /translation="MEWIRLIGIAIIVVGFIFKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5479..6183)
                     /locus_tag="ACL3GT_001829"
     CDS             complement(5479..6183)
                     /locus_tag="ACL3GT_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0517441.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(6239..7261)
                     /locus_tag="ACL3GT_001830"
     CDS             complement(6239..7261)
                     /locus_tag="ACL3GT_001830"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HGR0517442.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7393..9864)
                     /gene="parC"
                     /locus_tag="ACL3GT_001831"
     CDS             complement(7393..9864)
                     /gene="parC"
                     /locus_tag="ACL3GT_001831"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HGR0517443.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(10065..10269)
                     /locus_tag="ACL3GT_001832"
                     /pseudo
     CDS             complement(10065..10269)
                     /locus_tag="ACL3GT_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014166.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
     gene            complement(10284..12227)
                     /gene="parE"
                     /locus_tag="ACL3GT_001833"
     CDS             complement(10284..12227)
                     /gene="parE"
                     /locus_tag="ACL3GT_001833"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HGR0517444.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGFKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAVVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12363..13004
                     /gene="plsY"
                     /locus_tag="ACL3GT_001834"
     CDS             12363..13004
                     /gene="plsY"
                     /locus_tag="ACL3GT_001834"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HGR0517445.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(13047..>13906)
                     /locus_tag="ACL3GT_001835"
     CDS             complement(13047..>13906)
                     /locus_tag="ACL3GT_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR0517446.1"
                     /translation="KTEIVQELMTEFSLDILLKAIKLARSTYYYHLKQLDKPDKDQEL
                     KAEIQSIFIEHKGNYAYRRIYLELRNRGYLVNHKRVQGLMKVLNLQAKMRQKRKYSSH
                     KGDVGKKAENLIQGQFEGSKTMEQCYTDVTEFAIPVSTQKLYLSPVLDGFNSEIIAYN
                     LSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKG
                     NSPDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKLKGLSP
                     VQYRTKSFG"
BASE COUNT         4031 a         3109 c         2439 g         4327 t
ORIGIN      
        1 aattctcctt agaaagcgtc gattcaagtg ctatcactgt tcaaaaatga tggtcgctga
       61 aacttctatc gtcaagaaga atcaccaaat ccctcgtatc atcaaccaaa agattgctca
      121 aaagttaatt gaaaagattt ctatgaccga tattgcccat cagctttcca tctcaacttc
      181 aactgtcatt cgaaagctca atgacttcca ctttgagtgt aattttagaa atctgcctga
      241 gattatgtct tgggacgttg aaacagtccg gggagtgact gtttcaatcg ggagatggag
      301 atgagcttta ttgcgcaaga ttttgaaaag ctcaatatca tcactgttct tgaaggtaga
      361 acacaagcta tcatccgaga tcactttctt aaatatgata gagccgttcg ttgtcaagtg
      421 aaaatcatta ctatggatat gtttagtcct tactatgact tagctagaca acttcgcttt
      481 caaatttcta ggctcaggct gaaacagtct ctcagactgt ttcactcccg aatgctaaaa
      541 tcgttcttga tcgctttcat attgtacaac atcttagccg tgctatgagt cgtgtgcatg
      601 tccaaatcat gaatcagttt catcgaaagt ctcatgaata caaggctatc aagcgctact
      661 ggaaactcat tcaacaggat agccgtaaac tgagtgataa gcgattttat cgttctactt
      721 ttcgtatgta cttaaccaat aaagagattt taaacaagct tttgagctat tcagaagact
      781 tgaaacacca ctatcagctc tataataagg aaccagagaa atttttcgga cttattgagg
      841 acaatcttaa gcaggttcat cctctttttc agactgtctt taaaaccttt ctaaagaaca
      901 aagagaaaat cgtcaacgcc cttcaactac cctattcaaa cgccaaattg gaagcgacca
      961 ataatctcat caaacttatc aaacgcaatg cctttggttt tcggaacttt gaaaacttca
     1021 aaaaacggat ttttatcgct ctgaacatca aaaaagaaag gacgaaattt gtcctttctc
     1081 aaccttagct gacttcaacc cactacagtt gacaaagagc cagaaaaatc ccttgtttag
     1141 taaacaaagg attttgtgaa ttttcaattt gattaaagtt cgatatcacc aaacaaatca
     1201 gccattgaaa atcctgtttg tgtttctgga agttcgaaat cacgcttttc ttgacgtctt
     1261 ggacgacgtg gacgagcagc acgtttttct tctttttgtc cttcttcttg ggctggacgt
     1321 tcttcaagag ctttaataga aagtgatacg cgttctgcat ctgcgttaac ttcaagaact
     1381 ttaacttgaa cttcttgacc aactttaaga gcttcttttg gattttcaat ccgtttgtgt
     1441 gaaatttgtg atacgtgaac aagtccatcg atacctggca atacttcaac aaatgcaccg
     1501 aagtcagtca aacgtttaac tgttccttct actacatcac ctttagccaa tttttgctca
     1561 acgccatccc atggtcctgg tactgttgct ttaagtgaaa gtgatacacg tccttcttct
     1621 tcgttaagat caaggatttt cacttcaatt tcttcaccaa cagttacaac tgattttggt
     1681 gatacgttac gttcatgtga caattcagtc aagtgaacca atccgtcaac accaccaagg
     1741 tcgatgaaag cgccgaagct tgtgatacga gcaactttac cagttacaac atcaccaaca
     1801 gccaatttac cgaatacttc agcgcgagct gctgcagtag ctgcttcaac aacttcacga
     1861 cgtgaaagga tgaagcggtt ttctttagcg ttaacttctt tgattttagt atcaaattct
     1921 tgacctacaa aacgctcagc gttacgtacg aaacgagtat ccaacattga agctgggata
     1981 aatccacgaa caccttcaaa ttctactgaa agtccacctt taacggcacg cgttccttta
     2041 acagtaacaa cttcttcttc gcgaccaaca agtttgtccc atgctttgcg agcttcaagg
     2101 cgttttttag atacaaggta tgtaactgta tcagtatctt taccaactac ttgacgaagt
     2161 acaagaacat ccaatacttc tcctacttta acaaagtcat tgatatctgc atcacgatcg
     2221 tttgtcaatt cgcgaagagt caagacacct tcaacaccag ttccagagat tgcaacgtta
     2281 gcttgagtcg catcaactgt caatacttca gcactaacaa catcaccagt ctcaacttga
     2341 ctaacgctat ttagcaaatc ttcaaattcg ttcatctaaa aaatcctcca acaatcaagt
     2401 ttttcttaaa cttgacatac ttataatttt tttcctaagc acccgcaagg acatgttcat
     2461 atcattcacg tctttcaatt ataaaaataa aataccctaa gatattttgc tttttatctt
     2521 gattattacc taagaactgg ggtagctgga ttcgaaccaa cgcatgaggg agtcaaagtc
     2581 ccttgcctta ccgcttggct ataccccatt aatgaaatgg agagagaggg attcgaaccc
     2641 ccgaacccga aggagcggat ttacagtccg ccgcgtttag cctcttcgct atctctccta
     2701 caatcaacat ggactattat atcatgaaaa tttcaaaaaa acaagactta ttttgctaaa
     2761 ttataatttt caatcaaaat ttccacagct ttttccaatt ttttataaaa actatcgaca
     2821 ttcccattct ttataatggc aaattgtccg tctaattcgg caatttctcc gataactttt
     2881 ttaccgatag tcaatgtata accttcaaaa ctgtctttac caacattaac tttggcatcc
     2941 gctacttgaa tttcgatttt tttatctttc ttgctcattt catacctctc ttcacttttt
     3001 ctattttaca agaaaatcct aaaactagca agaaaaaact ctatatcagg cttctctgat
     3061 atagagtttt atgtaaacaa cctcaatcga tttagcatag ctaatagtta gtaaacaagc
     3121 ataattgact atccttttta ggttatcagt gagtctcacc gcctactaac tgcaaatcct
     3181 tatctttgta gtctacaata gcttcaatag ctacctctat gcctcttaca atatcacata
     3241 gactcattcc tgcagtattc ggcttattta ctacttgttc catcatatat ggaatatgca
     3301 tgaaacctgc tctcatatta gggaattttt tatccactaa ataaagagct tggtacatca
     3361 aatgattgca aacaaaggtt cctgcactat tggatacaac tgccggaagt ccctgttttt
     3421 tgatagcttg taccatcgct ttgataggta aactactaaa ataggccgat gctccatcaa
     3481 tacgaatcgg tgtatcaatt ggttgattgc cttcgttatc aggtatgcga gcatcatctt
     3541 gattaatagc cactcgttca ggtgttaagc cggtcctgcc gcctgcttgt ccaatacaaa
     3601 gtacagcatc tggttgatat cgtaatattt ctgcctctaa aacttctgac gacttataaa
     3661 aaaccgttgg aatttctacc cagcgaactt cagccccatt aatctcagat ggtaataatt
     3721 ttacagcctc caaagctgga ttaatctttt cacctccaaa aggattaaaa cctgtaacca
     3781 atattttcat tttattttcc tttactaaaa tgcgagaaag tacattaaga atatgtgaat
     3841 aacaatcatt actagagcaa cacctgcttg agcctttata acgccattct gatctttcat
     3901 atccatcaat gctgctggta gagcgttaaa attagcagcc attggggtca ataaggtccc
     3961 acaataacct gctgtcatgg caagagcacc agccacaatt ggattagctc ccagagcaaa
     4021 tacaaaggga actccaacac ctgctgtaat aacggtgaat gctgcaaaag catttcccat
     4081 aatcattgtg aatagaacca ttccaagaac ataggccaaa actcctataa agcgactatc
     4141 tgaaggaaca ataccgctaa tcagatgaga gataacatca ccaacacctg ctacagtaaa
     4201 aatagccccc aaagccccta ataattgagg aacaatacca cttgttgaaa cttgctgagt
     4261 cattcgatta ttttctgata acagactctt agggtgacta ttggtaatca caagaacaga
     4321 aattgtagca aacaaggcgg caaggctaat cgaaatcttg ctaaattctg gaatcatttg
     4381 cgctaagacc aacgcaagta ttgccatcag cataactgga ataaaaattt tatttttcaa
     4441 cctgttagat tcaatattgg ctttcatttc atctaaggat ggcaaggttc cgatacggac
     4501 ttgcttaaac aatgttaaca gcgataatag gattacaata ataccaatac tcatatttgg
     4561 catataggaa ccacctataa acgtaataga caatagagtc caaaatgcag atgtcccaag
     4621 tcgaactggg tttgttttat ctttataact acaataggct gtatggagaa attgacaacc
     4681 aatcacaata taggtcaact ctaatagttg ctttgccaac tctgtcattt ttgttctcct
     4741 cccctagtct tttttgatat caatttttta tcaaataaat aattgtaaat ccccactaca
     4801 ataagtgtta taacagcaac aataatagat gtagaagcaa tccctgcata attgctttca
     4861 tagcctaact gatctaatgt tccccctatc aagaggactc ccccagcacc tacaaacgta
     4921 ttttgagcaa agaaatttcc aaaattttca ttcgcagccg cacgcgcttt tattgtctca
     4981 tcttcaacct ctgttaactt tctacctaat tgagactctg cagctgcttc tcccataggt
     5041 tgaaccaaag gtctgacaaa ctgagggtgt cctcctagac gaattgaaaa gaaaccagct
     5101 aactctcgaa taaaaaaata aactgtatag aagtttccaa ctgtcagacc tttaatcttt
     5161 cgaatcaaat cgattgatcg ttgcttgagt ccaaaggttt ctgacagccc cacaagaggc
     5221 aaggtaacca taaaaatcgt gagcactcgc tgattgctaa attcttttcc caaaatctcc
     5281 aaaaattcaa cgagagaaac acctgaaact aaagctgtaa ccaaaccagc taagactact
     5341 gttgcaattg tatcaaattt aaaaataaaa cccacaacaa tgattgctat tcctattaat
     5401 ctaatccact ccatatcaaa ctcctttata ttcaaaatga cagtatttta aaaattttat
     5461 caagatcaat accattcctt atttaatgta tttttctagt tctttttggt atttgctatt
     5521 ggattccaat ttttcttttt gccatttttt aaaaacctcg ttatattctt ttgttgtaac
     5581 aatatctttt tgcaatttca ttcctttaaa gatatatggt tcccccttaa taccaacttg
     5641 tgagtatggt tttgagaatg gtactacgtt acttacaact ggagaaccac cagatgaagc
     5701 tgttggcatc aataatgaac tatctgtcga ccaagcttga gctttggcat atttttcata
     5761 tctcttctct aggtcagtgg tctcagaaac agcatcttct aacaatttct tatatttatc
     5821 caaaccaggt ttagctacaa catccttatc ttttcctttc gtaataccaa ggtgtttcat
     5881 ggcagaacca gattttggat ccataatatt caagtaagac gctggatctt gatagcttgg
     5941 agcccatcct gtactattca aatcatagtc tttttgagaa ggagcaacat tgccgtattt
     6001 atcattttcc atcaaaccat caataacatt tccaataacg tctgtcctcg atgttcgagt
     6061 cgctatactg tagcccaatg atgctggatc tactgcatag acataagaaa atgttgtcgg
     6121 tgcatctgct tctttatcag tttttccaca agccactaaa atagctgacg tgctcaggac
     6181 cactcctgct gttaagagcc actttttcta tttcataaaa aatctccttt ggtttatttt
     6241 aatctacttt tacaatccaa ccttctggcg cttcaatatc gccaaactga atacccgtca
     6301 attcattata taatttacgc gtcacaggac ctacttctgt ttcactatag aatacatgga
     6361 aatcatcacc atgttgaata cctccaattg gagaaataac cgctgctgta ccacaggcac
     6421 ctgcctctac aaaacggtca agattatcaa ttggaacatc accctcaata ggagttaatc
     6481 ccaagcgatg ttctgccaaa taaagcaagg aatacttggt aatagatggc aagatagatg
     6541 gactcaatgg tgttacaaat tcattatcag ctgtaattcc aaagaagtta gctgatccga
     6601 cttcttcaat ctttgtatga gttgatgggt ccagatagat aacatctgag aaatgacgtg
     6661 acttggccat ttttcctggt aagagacttg cagcatagtt tccaccaacc ttagccgcac
     6721 ctgtaccatt tggtgctgca cggtcgtact catcctgaat caagaagttg gttgggacca
     6781 aaccaccttt aaagtaattt ccaactggca tagcaaagat ggtgaaaatg tactcttctg
     6841 ccggttttac cccgataata tctccgacac caatcaaaag agggcgaaga tataaggttc
     6901 cacctgttcc gtatggtggt acgtattctt cattcgcacg gacaactgct ttacaagctt
     6961 ctacaaacat gtctgtcgga acttgtggca tcaagagacg gtcacatgta cgttgcagac
     7021 gtttagcatt ttcatcagga cggaacagtt gaacactgcc atccttagta cgataagctt
     7081 tcaaaccttc aaatgcttgt tgtccatagt gaagacttgg agaagactct gaaatatgca
     7141 aagttgcatc ctctgtaagc tctccttgat cccattgtcc atttttgaaa tgagcaagat
     7201 agcgataagg taatttcata taggaaaaac cgaggttttc ccaatcaatc gttactgtca
     7261 tattccactc cttattctaa aaacctattt cttatattct acactatttt tctaaaatag
     7321 caagtatatt ttgtaatttt cagaaaattt ctccaataaa aaccagctct tagaactgat
     7381 tcttcatttc acttatttat cttcagtaac tacttcctga agataagcgt caaaaacttc
     7441 ttcatctgaa atcgtgtcag aaatgaagct tccattgcta gtgcgttctg acaagttcaa
     7501 gtcttgcaat cggctttcat agattgttcc tttattggat tggacaagca gagtttggtc
     7561 gttcacatcc acttccgtac tgaagaaatc gccaacaaat ccttgctctg caactgctcc
     7621 tgccaagaag acacgatgcg gtttgttttt caactcacgc aagacttgta atcctcgttt
     7681 ggcacggctg gttgctagaa tttcctcaat ggaaacacgt ttcaagcttc cacgctgggt
     7741 caagaggtag aaggacgaag tattacagat aaagccagat tggaggacat catcttcttt
     7801 caaattcata gccttgacac ctgctgcctt agcaccgaca accggaacct cttcgatatt
     7861 gaaacgcagg gcataaccat tttgactaac caagacaaca tcatctagtt taatcggagc
     7921 cactgctaca atctgatctg tatcgtcttt gagcttagca tacttgacag acttagatct
     7981 ataggtccgc catggagtga attcttttcg ctctacccgt ttgatttgac caaggcgagt
     8041 cactgcaaag taggttgtcg catcgtcaaa ctgatccagt acttccacat aaaggatttc
     8101 ttcattcgtt tcaaagtttg tgatggtttg gctcagatgc tctccgatgt ccttccaacg
     8161 aatatctgcc aactcatgga ttggtctgta gatgacattt ccaagacttg tgaacatcaa
     8221 gaggtgctgg gttgtcttgg cagattgaac aaaaatcaaa cggtcatcat cacgcttgcc
     8281 aatttcttcc aaggtggaag ccgcaaagga acgtggactg gtacgcttga tgtaacctgc
     8341 cttggtcacg ctgacgtagg tatcttcctc agcgataaga ctagctgtat caatctcaat
     8401 tgctttcgca gtgtcttcta aagaactcaa acgaggagtt gcaaatttct tcttgacctc
     8461 acgaagttct ttcttcatga gattgtacat agtcctttca tcaccgataa tagccgccag
     8521 catagcaatc ttctcacgaa gctctgcttc ttcttcctgc aagacaacca catcggtatt
     8581 ggtcaaacgg tacagttgca aagttacgat agcctcagcc tgttcttccg taaaatcata
     8641 gctaactttg aggttttcct tggcgtccgc cttattctca gaagcacgga taagagcaat
     8701 gacttcatcc aaaatcgaaa tcacacgaat caaaccttcg acgatatgga gacgtttctc
     8761 agccttttct ttgtcaaagc gtgaacgcgc caaaatcact tctcgacggt gagcgatgta
     8821 gctagacagg attggaacaa tcccaacctg acgaggtgtg aaattgtcaa tcgccaccat
     8881 attaaagttg tagttgattt gtaggtcggt gtacttaaat aagtagttga gaacaagctc
     8941 agtattagcg tctttcttaa gttcgatagc gatacgaaga ccatcacggt cagactcatc
     9001 acgaacctca gcaatcccag ctaccttgtt attaacacga acatcatcga ttttcttgac
     9061 tagattggcc ttattgattt cataaggaat ctcagtaata acgatttgtt ccttaccacc
     9121 ttttagcttt tcaatttcag tcttggaacg aacaaccacg cgccctttcc cagtttcata
     9181 agctttcttg atttcatcac gaccctgaat aatagcccct gtagggaagt ctggtccagg
     9241 caagaattcc atgagtttat caatctttgc agttgggtgg tcaatcatgt aaactgcagc
     9301 atctatgacc tcagctaaat tatggggagg aatgtctgtg gcataaccag ccgaaatccc
     9361 agtcgaacca ttgaccaaga ggtttggaaa ggctgctggc aagaccgttg gttctttctc
     9421 cgtatcgtca aagttccatg caaaaggaac tgtatttttc tcgatatcct gaagaaggta
     9481 acctgcaatt tcagacaaac gtgcctcagt ataacgcata gccgcaggag gatctccgtc
     9541 catagaaccg ttattaccgt gcatttcaac tagaatctca cgatttttcc agttctgtga
     9601 catacgaacc atggcatcat agatagaaga atccccgtgt gggtggaaat tccccatgat
     9661 gttcccgact gacttggccg acttacggta gctcttgtca aaagtattgc tatccttatt
     9721 catagaataa agaatacggc gctgaaccgg cttcaaccca tcacgaatat ctggcaaagc
     9781 ccggtcttga ataatgtact tggagtagcg accaaagcgc tctcccatga tgtcctccag
     9841 ggacatgttt tgaatgttag acataagata caaagcccat aaaataccaa gtgaaaatag
     9901 aaaattcttg aagtaagcaa actcacaaga gaatttatct ttttcacaca gtatctaggg
     9961 cgtgttcaac tcctttcaaa gaatgtagag taggttttta tgcagtaaaa gatattttac
    10021 gggaattcct cccgtgttca gttacgataa gtaaccaaac tatcctgttt gtatttttca
    10081 atatgaaaat ctggttttcc aaaattagtc ttagtttgtg tcttagccgc tcccttaagc
    10141 gcctctttga gataagcact catagcagat tcttcattaa taatcctgca attttttcaa
    10201 accaagattt tcaaactgct ttttcacata gtcattcaca tccgactcta atttccagtt
    10261 tactaacata ttattttctt tcattaaaac actgtcgctt cttctagcgt aaacttgaca
    10321 ttatcttcaa tccatttacg gcgtggttct accttatctc ccatgagaac attgacgcgg
    10381 cgttcggcgc gcgctaaatc ttcaattgtg acacggatga gggtacgtgt ttctgggttc
    10441 atggttgttt cccagagctg gtccgcattc atctcaccaa gtcctttgta tcgttggagg
    10501 gtagcgcctt taccgaactg tttacggagt tcttctagtt ctccgtccgt ccaagcgtag
    10561 gccacttctt ctttcttgcc tttacctttg gacatcttat aaagaggtgg gagggcaata
    10621 tagacatgac ctgcctcgac tagcggacgc atgtaacggt agaaaaatgt caagagcaag
    10681 gtctggatat gggcaccgtc ggtatccgca tcggtcatga taatgatctt atcatagttg
    10741 gcatcttcaa tagagaagtc tgctccaaca cccgcaccaa tggtataaat catggtatta
    10801 atctcttcat ttttgaggat atccgccatc ttggccttgg ctgtattgac aaccttacca
    10861 cgaagaggta gaatagcctg gaacttgcgg tcacgacctt gtttggcaga accaccggca
    10921 gagtccccct caactagata gagttcattc ttagcaggat tcttagattg ggctggggtc
    10981 aatttcccag acaacaagcc cttatctttc ttgtttttct tcccatttcg gctctcatca
    11041 cgcgccttac gtgctgcttc acgagcatca cgggccttga tagccttgcg gatgaggtta
    11101 gaagctaatt ccccattttc cataaggaaa aaggtcaact tatcagccac tattccatcc
    11161 acaactgggc gagctagggg gcttcctagt ttatccttgg tctgtccttc aaactgcaag
    11221 tgttcttcag gaactaagat agaaagaacg accgctagtc cctcacgata gtctgaacct
    11281 tcaaggtttt tatctttttc cttgagaaga cctgttttac gtgcatagtc attcatgacc
    11341 ttggtaatgg cagacttgaa tcctgtctcg tgcgttccac cgtccttggt gcgaacgtta
    11401 ttgacaaagg atagaatgtt atctgagaat ccgtcattgt actggagggc tacttccact
    11461 tgaaaaccat tgtcttcccc ttcaaagtaa agaactggcg tcaagatttc cttatcttcg
    11521 ttgagataag aaacaaaatc ttgtactcca ttctcatagt ggaactcaat cgcttcatct
    11581 gttcgcttgt ccgttaaaga caaggtcaca tttttcaaga gaaaggctga ttcattaagg
    11641 cgctctgaaa tggtattgta cttgaaatct gtcgtagaaa agatagtcgc gtcaggcata
    11701 aaagtaactt tggtgcctgt tttagacttg ggtgctgtac cgattttctt caaagtcgtg
    11761 acaggttttc caccattttc aaaacgttgc ttgtaaactg cgccatcacg ggtaatttca
    11821 acttctaacc agctagaaag ggcgttaaca acggaagaac ccactccgtg aagtccacct
    11881 gatgtcttat agccaccttg accgaatttc cctccggcat gaagaatggt aaagataacc
    11941 tcaacagttg gaattcccat agcgtgcata cctgtcggca tcccacgtcc atggtcttga
    12001 accgttagac taccgtcttt attgatagtt acatcaatac gatcaccaaa cccagacaag
    12061 gcttcatcga ctgcattatc aacgatttcc caaactaggt gatgaagacc agcgccatcg
    12121 gtcgatccaa tatacatccc tggacgtttt cggaccgcat ccaacccttc tagcacctga
    12181 atagcatcat cattataatt gttaatattg atttcctttt ttgacacaag gaacctccta
    12241 ttcgttcatc tttactattc tacaggtttt ccaaggattt tgcaaaattt ttctttctcc
    12301 gatgtgacaa tttcagcaga gattctctgc ttttctttcc caattcatga tataatagga
    12361 gtatgattac aatagtttta ttaatcctag cctatctgct gggttcgatt ccatctggtc
    12421 tctggattgg acaagtattc tttcaaatca atctacgcga gcatggttct ggtaacactg
    12481 gaacgaccaa caccttccgc attttaggta agaaagctgg tatggcaacc tttgtgattg
    12541 actttttcaa aggaacccta gcaacgctgc ttccgattat ttttcatcta caaggcgttt
    12601 ctcctctcat ctttggactt ttggctgtta tcggccatac cttccctatc tttgcaggat
    12661 ttaaaggtgg taaggctgtc gcaaccagtg ctggagtgat tttcggattt gcgcctatct
    12721 tctgtctcta ccttgcgatt atcttctttg gagctctcta tcttggcagt atgatttcac
    12781 tgtctagtgt cacagcatcg atcgcggctg ttatcggggt tctgctcttt ccactttttg
    12841 gttttatcct gagtaactat gactctctct tcatcgctat tatcttagca cttgctagtt
    12901 tgattatcat tcgtcataag gacaatatag ctcgtatcaa aaataaaact gaaaatttgg
    12961 tcccttgggg attgaaccta acccatcaag atcctaaaaa ataaaacgcc agttctgtac
    13021 tgaccccaaa aagttagaca attaatttat ccgaaggatt tagttctgta ttgcacaggg
    13081 ctaagtcctt ttagttttac cttaattcgt ttattgttgt agtaatcaat atagtctaca
    13141 atggcttgtt ccaattgctt aagcgactga aacgacttct cataaccgta aaacatttcc
    13201 gatttcagaa tcccaaagaa ggactccatc ataccattgt ctgggctgtt acccttacgt
    13261 gacatggatg cttgaattcc cttaccctca agaaactgat gataagaatc gtgttgatat
    13321 tgccagcctt ggtcactatg gagaatcgta ttctcgtagt gcttctctgt gaatgcctgt
    13381 tccaacattg tttgtacttg ttctaagttg ggtgaagttg aaagattata ggcgataatt
    13441 tcgctgttaa aaccatctaa aactggtgat aagtaaagct tttgagtact tactggaatg
    13501 gcaaattcag tcacatctgt gtagcactgt tccattgttt tagagccttc aaattggcct
    13561 tgaatgagat tctctgcttt cttaccaacg tctcctttat gagaagaata ttttcgtttc
    13621 tgtcgcattt tagcttgtaa attgagtact ttcatcaagc cttgaactct tttatgattt
    13681 accagataac cacgatttct tagttctaaa taaatccgac gataagcata atttcccttg
    13741 tgttcgataa aaatggattg aatttcagct ttaagctctt ggtccttatc tggtttgtct
    13801 agctgtttca agtgatagta gtaggtcgaa cgagctagtt taatggcttt tagaagaata
    13861 tctaacgaaa actcagtcat taattcttga acaatttctg tctttc
//
LOCUS       DBEJJV010000050        13644 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.050, whole genome shotgun sequence.
ACCESSION   DBEJJV010000050 DBEJJV010000000
VERSION     DBEJJV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13644
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.050"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(778..1647)
                     /gene="gla"
                     /locus_tag="ACL3GT_001836"
     CDS             complement(778..1647)
                     /gene="gla"
                     /locus_tag="ACL3GT_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaglyceroporin Gla"
                     /protein_id="HGR0517447.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIVA
                     AIAAVAVFKFLYL"
     gene            complement(1871..2392)
                     /locus_tag="ACL3GT_001837"
     CDS             complement(1871..2392)
                     /locus_tag="ACL3GT_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HGR0517448.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAS
                     LGLGFFKKKEDEK"
     gene            complement(2350..3456)
                     /locus_tag="ACL3GT_001838"
     CDS             complement(2350..3456)
                     /locus_tag="ACL3GT_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HGR0517449.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVVVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(3567..3821)
                     /locus_tag="ACL3GT_001839"
     CDS             complement(3567..3821)
                     /locus_tag="ACL3GT_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517450.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(4161..5006)
                     /locus_tag="ACL3GT_001840"
                     /pseudo
     CDS             complement(4161..5006)
                     /locus_tag="ACL3GT_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078372828.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            5240..6958
                     /locus_tag="ACL3GT_001841"
     CDS             5240..6958
                     /locus_tag="ACL3GT_001841"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HGR0517451.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            7069..7416
                     /locus_tag="ACL3GT_001842"
     CDS             7069..7416
                     /locus_tag="ACL3GT_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HGR0517452.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFIHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(7695..8531)
                     /locus_tag="ACL3GT_001843"
     CDS             complement(7695..8531)
                     /locus_tag="ACL3GT_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HGR0517453.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(8544..9173)
                     /locus_tag="ACL3GT_001844"
     CDS             complement(8544..9173)
                     /locus_tag="ACL3GT_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0517454.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(9183..9824)
                     /locus_tag="ACL3GT_001845"
     CDS             complement(9183..9824)
                     /locus_tag="ACL3GT_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0517455.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(9970..11199)
                     /locus_tag="ACL3GT_001846"
     CDS             complement(9970..11199)
                     /locus_tag="ACL3GT_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HGR0517456.1"
                     /translation="MNNSQQMLQALEEQDLTKAEYYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLMLGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLAAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(11189..12355)
                     /locus_tag="ACL3GT_001847"
     CDS             complement(11189..12355)
                     /locus_tag="ACL3GT_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HGR0517457.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVIFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            12499..13512
                     /locus_tag="ACL3GT_001848"
     CDS             12499..13512
                     /locus_tag="ACL3GT_001848"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HGR0517458.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNEFHVPEAVCIR
                     FAP"
BASE COUNT         4166 a         2924 c         2402 g         4152 t
ORIGIN      
        1 taaaaattta actaattaat agaaagtact aaatagactt atccttcaag gagttttcag
       61 cattatccat ccactcactt gctgaaaatg taaacagtct ctggtttata tagtaaaatg
      121 aaacaagaat agagcaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa
      181 gtagatgtgt actattctag tttcaatcta ctatacaacc tcaaaactgt gttttgaaca
      241 acctgcggct agcttcttag tttgcccttt gattttcatt gagtataaaa ttgcagataa
      301 aacgataaca atcataggac tcagcagagt caatgtaggt cgaagaatac ccccctaatc
      361 gcttatttta tagcaaaatg aaatagaaac tgaacatttt gttgaggaag gtaaatcaat
      421 tcctcacaat gtttgagaaa gaagggagga ctattccaac ttcaacccac tataaagcag
      481 acttacaaga tagggaaccc atctccgata atatatagta gaatgaaaac tgcacaattt
      541 gattggagaa ttcaaaccaa tttctcacaa tgttttagaa acaagggtct attatttcaa
      601 ctgcaaccta ctatagtcca ttgaagctgg aatagcccac tgagacttct aaaccactgc
      661 tggagaggag tttgtttaga gtttctttca tttccctaaa aaatcaaaaa gagagaacca
      721 gtctgatcct ctcttattta tagatggtgc tcactcaaat gttaaaggag ctatttctta
      781 gagataaagg aatttgaata cagctactgc cgcaattgct gctacgatag gtgctactac
      841 tggtacccaa gaataccacc attttgaatc gcctttatgc tcaccaagaa ctgattttgg
      901 aaggaaagca tgaaggagac gtggtcccaa gtcacgggct gggttcaagg caggtcctgt
      961 aggtcctcca agtgatgtta ccaaagccat aacgaggaat ccaagtgcca agtgagccac
     1021 agaaagtcct gaagcagtgt gtggagccac ctgtgcttta atagccaagt cagaaaaatc
     1081 aactgtttgt cctgcttcta ttgccttttg tttcatgaat tgaagcactt cagcaccaaa
     1141 gaagttttta gtcaaaccaa gagctgcaaa gaacaaaaca aatgaaccaa caaactcatt
     1201 aatcaaacca ttgacagttg ctgcatagcg actttctttt gtaccatggt caatacttga
     1261 aatagttgag aaagttccca agatgttatt tgggttttca gttttcaagt agaatggacg
     1321 gtatgttgcc acaactaagg cttggccaaa gatagctccc aagacttgcg cgataatata
     1381 aggtaccact tgtgcccaag ggaaaagacc gctaactgca agccctagag tgaaagcagg
     1441 gttgatgtga ttcccagata cgttaccaaa catcaaggct gggatcataa cccccatacc
     1501 ataaccaaca gcgatgacga tccagccact ttggtgacct ttcgtacctt taagttcaac
     1561 gttggcaact gcaccattcc caagaatgat caaaatggca gttcccaaaa attcagtggc
     1621 atacttcagt gcccatgtga aatccatttg ctagattctc cttaaaattt tttagatatt
     1681 ccttatttta tcaattttta ccctatttag caactgattt ctggaaatat ttttaaaaaa
     1741 ataggattca tagtttccca gttcaacgga cttgtaagcg tttttattct tcacgaaaga
     1801 cctcgttctc aaaaccagga aaaaagccca catctgtgag cttttcctgg ttcctagatt
     1861 ctaaaatcta ttatttttca tcttcttttt tcttgaagaa tcctaatcct agactagcta
     1921 acaaggtcat gataccagca ctagccaagg tagcattagc ttctgtacct gtgtttggca
     1981 attcctctct cttacctgtc tcataagtcg gaacttctgg gtctggattc actggagttt
     2041 cagtttttgg agtacctggg tctggagttg gtttatctgg tgttgataaa cggtcatacc
     2101 ttaccgttat ttctttatca ctagagtctg acgtaacttc ttgtgattca actgttggaa
     2161 tatctggatc tttgtacttg tcaatcttac cagatacaac ctcgtcccag tttcctgttg
     2221 tccattcacc gtaggttaca actcccgtga ccttgttctc agtttttgta cggcttaagg
     2281 ttacaggttg aacaacatct tcttttacat tttggttcgt aactttatca acgtaatgaa
     2341 tgatacgcgt tatagtcttc gtctcagtag aggttgctgt tttgggaacc actgtttcct
     2401 caacattctc acggtagtaa tagtcaactg ttgcaccgtc ttctggtacg catttgcagg
     2461 agttgctacc aaggtgtatg ttgttttcct tgtgataact cggtcttctt tgtcctcagt
     2521 tgttgttttc ccttcaatag tttttgattc tgtggtatac tcagaaccta tcgctaaatc
     2581 agcttttata acagactctg ccaacttctc ttggctacct tctttatagt aattggctgt
     2641 tactgtagca gtggttggcg cttcgctttc tctataaact aaggtcactg ttctaccttc
     2701 gcttacaata ttcccagtta aacttgcaga atttgtatct gcttctttaa aagtataata
     2761 ttttccgtca gtagtagtca tgctactgag ttttttatct gtgacattgt agctggtacc
     2821 aatcagttgt tttttattgg taatgtaggt tccgtcactt tctttttctc caattccagt
     2881 atcatttttc aatgatagca aacgcccttg ttcatcaaca tagcgaactt tcacattttc
     2941 tgagattagt tctgccaatt ctgaggtttt tttctttttc ttgatttctt cggttatttt
     3001 ccctttctct tcttcgggaa tatttagttt tggaatgatt ttttcaacaa cggttcgtga
     3061 tggttccaca gtatcttgga tgactgaaaa gtcagctaga attgggagat tatactgaac
     3121 acggtgactt tgagtgttta ctactactct ttcattattc tctgaaaata cttgtacggt
     3181 ataagaaaca acatcttttc ctaatagaac atccccagta gagaaatagc cgccttttcc
     3241 tagtttgcta tctccagagc ccacttcttt cctaatctta tcagatagtt ttttaccagt
     3301 cagtacattc gttcgcacaa tccctttgtc tacccctaca aagtgggaga actttttgaa
     3361 ctcttcagaa ccagatctag cccaaccatt attaagggca tttgcttttg tatttgtatt
     3421 ctctctcaaa agtttggcga ttagaattat attcatcggc acttagagtt gctgctatat
     3481 ctgactcttg aataccaact tccttactac catttctagc ggcagtatat gtgtatttat
     3541 ttgtttctac ttctagctga ttatccttaa catgataggt aattttctcc tggtataaga
     3601 gtcttcagta gtttatatgc tctgtcatca tctttagctt tagaagcagc tgagtttagc
     3661 caagttgggg tattaggagt atctttatca gcctgtttca agacattatt caagtcattt
     3721 gctagcctat tggttgtcct cactgtgaaa gttttcttcc agtctgaacc acttttatta
     3781 gacttagata tgctcatgaa atcctggtca acattcaaca caatatcgcc ttgtttttta
     3841 gcatcttccg ttgcttctgc ttcaaattga tcatggagtt tttgttgctc tggtgtatag
     3901 tttttttatt tacacgattt aatgtactat tttttatttt agtattaaga actccattaa
     3961 tacgattttt aaactctgct tcaaaaaatc ccttaatttg ttggtgcgca agttcaacat
     4021 tcaaaccttt cttatacaag tcttcattct aaacgatttc ggctacacgg tgaatggttt
     4081 gattgtatac cgtcttctct taaccagcag tatccttagt tttaatgact actcgatagg
     4141 ttcctttaga accgttatag tcatctagtt ttaaaaaagc attccaaaca ttcaaaaata
     4201 gttggaactt cccttaataa atccgtcact ttctttttca agatagccca agcttgctca
     4261 ataggattca aatccggtga ataaggtggt agaggtaaga aaaagtgttt atcttggatg
     4321 cagagttcat ccaaaatgtt cttgggatga aaactagcat tgcccatgac aataacatga
     4381 ggtgtcttca aagcaggtag gagttgcgtt ttgaaccact ccacaaagaa atcgcttgtc
     4441 atgcttttct tgtaaatcat gggagctata aactctccgt ctacttgtcc tgcaacaatt
     4501 gaagttcgct caaaacgacg tccgctaatc tttttataga ctttctcccc tctaggagcc
     4561 cgtgcataag gacgatagag gtagcggtcg attcctgttt catcaatata tacgattggt
     4621 aaatctttta ggttatccaa aatatcaaga aactcagcga ctttctctgg ctcttgttcc
     4681 ttaaagctcg tcatcttttt ttaaagtgac cttaatatac tttaaagctg cccatacgga
     4741 gggcagagca caatcaaaat gtgccgcaat ttcccgtaaa aaagcatctg gatgagcctc
     4801 tacaaaggct ttcaattcct ctaaaggaat ctttcggttt ttgacgactc gctttttcct
     4861 ctctatgtgt ccttgttcac atctttcttt tcccacgtga agagagttct gacgccaaca
     4921 ccaaaaaact tggctgcctc gacatggctg tgcccctctt tgatgtaatc taatgctcgc
     4981 tgtttaaaat cagtactata tgccatagct ttattataat atgcttgttt aaaactaagc
     5041 aactatatca atgttttgtt attagaagac ttactttttt tactgaaatc gaatttttcc
     5101 taacctcaac atcatataac cccaaaattc aatctgacct ggtttgaaga gatgttcgaa
     5161 gcagataagg ttttactaaa actaaaaaaa atgatataat caaactgatt aaatgtttta
     5221 aaaataaagg agaatttgaa tgtcttacca agaaaattac cagaaatggg ttgattttgt
     5281 ggagcttcct gactaccttc gtcaagattt ggaaaatatg gacgaaaaaa ctaaggaaga
     5341 tgccttctat acaaatcttg aatttggtac tgcaggtatg cgtggcttgg ttggtgctgg
     5401 tacaaaccgt atcaacatct acgttgttcg acaagctact gaaggattgg ctcgtttgat
     5461 tgagtcaaaa ggtggaaacg agaaagaacg cggtgtagca attgcctacg atagccgtca
     5521 cttctcacct gagtttgcct ttgaatctgc ggcagttctt gctaaacacg gcatcaaatc
     5581 ttacgtattt gaaagccttc gtccgactcc agaactatca tttgcagttc gtcatctcaa
     5641 ctgtttcgca ggtatcatgg tcacagccag ccacaaccct gctccattta acggttacaa
     5701 ggtttacggt gaagacggtg gacaaatgcc tccacacgat gcggacgctt tgactactta
     5761 tatccgtgca atcgaaaacc catttgcagt tgaagttgct gatgtggaaa ctgaaaaagc
     5821 ttctggcttg attgaagtta tcggcgaagc tgttgacgta gaatacctta aagaggttaa
     5881 ggacgtaaac atcaacccag ccttgattga agaatttggt aaagacatga agattgtcta
     5941 cacaccactt catggtactg gtgaaatgtt ggctcgtcgt gctcttgccc aagcaggatt
     6001 tgactctgtt caagttgttg aagcgcaagc aactgctgac ccagacttct caactgtaac
     6061 atctccaaac ccagaaagcc aagcagcctt tgcccttgct gaagaacttg gtcgtcaagt
     6121 tggtgcagat gttcttgtcg caactgaccc agacgctgac cgtgttggtg ttgaagttct
     6181 tcaaaaagat ggtagctacc tcaacctttc aggtaaccaa atcggtgcta tcatggctaa
     6241 atacatcttg gaagctcaca aaaacgctgg aactcttcct gaaaatgccg ctctctgcaa
     6301 atctatcgtt tcaactgact tggtaacgaa gattgctgaa agctacggcg caactatgtt
     6361 caacgtcttg acaggtttca aatttatcgc tgaaaaaatc caagaattcg aagaaaaaca
     6421 caaccacact tacatgatgg gatttgaaga aagcttcggt tacttgatta aaccatttgt
     6481 acgtgataaa gatgccatcc aagccgttct tgtcgttgct gaacttgctg cctactaccg
     6541 ttctcgtggt ttgacacttg ctgacggtat cgaagaaatc tataaagaat atggctacta
     6601 cgcagaaaaa acaatctctg ttactctttc aggtgtcgat ggtgctgaac aaatcaaagc
     6661 gattatggct aaattccgca acaatgctcc aacagaatgg aacgcaacag ctatcactgt
     6721 cgtagaagac ttcaaggcac aaactgctac tgttgctgac ggtactgtta caaacttgac
     6781 aactcctcca agtgatgtgt tgaaatacac acttgctgac ggttcatgga ttgccgttcg
     6841 cccttcaggt acagaaccaa aaatcaagtt ctacattgca gttgtagggg aaaccaacga
     6901 agaatcacaa gctaagatta ctaacatcga agcagaaatc aatgcatttg taaaataaag
     6961 acctataaaa gatgagacca accaacctca tcttttttcg tatcaaatct aagcaatttt
     7021 agaaacttta tggcatacta gacttatcaa tgaaagcgag gtaatctcat ggaacaattt
     7081 ttagataaca tcaaagacct tgaagtcact acagttgtgc gtgcgcaaga agctcttgat
     7141 aaaaaagaaa ctgcaacctt ctttatcggt cgcaaaactt gcccttactg ccgtaaattt
     7201 gcaggtacat tgtcaggtgt cgtagctgaa accaaagctc acatttactt catcaatagt
     7261 gaagaaccaa gccaactcaa tgatttgcaa gcattccgct cacgttatgg aatcccaact
     7321 gtaccaggtt ttattcatat tacagatgga caaatcaacg tccgttgcga ctcttcaatg
     7381 tcagcacaag aaatcaaaga tttcgcagga ttgtaaaaaa tcagctaaca agtcttaaaa
     7441 tcacaaaaac gcataatgta aggtgcaaaa accttgatat tatgcgtttt attgttccta
     7501 aaacagttac atcagcattt cattacagaa cattttaatt ttggaagtca aatcaatttt
     7561 taacaatgtt ttagaaatca cagtgggcta ttccatattc aattatccag attcaatcgc
     7621 tattatcgtt ttcctagatt acaaaaaaaa ctacgttttg ctaatcaaaa cgtagtctca
     7681 gccactattt tatcttactg tccttctttt acttctttgg ttgctacatc ttctccaaac
     7741 catttttggc tgatttcttg gaacttgccg tccttgtaaa gactagaaaa agcttcattt
     7801 atcttcttaa ccaaggttgt atcttcctta cgggctccaa ccgcaaaagc ttctgtttct
     7861 agtccaactg taaagacatt ataatcgttt aaaacacctt ctgcttctaa ataatagttt
     7921 gcatagacac ggtcaatcaa tagaccatca attcgatcgt ttttcaaatc aatcaaggct
     7981 tcattaaagg tttggtattg attcgcttcc ttattagcga caatattctt caaaatttct
     8041 ggatttgctt caaagtccgc ataaccagat gaaccagctt gagctcctaa tgtctttcca
     8101 gtcatatcct ttgcagtcgt gataccagat gattttttcg taaccaatac ctgctcattc
     8161 ttcatatatg agttactgaa agccaccttt tcacggcgtt cgtctgtagc ggaatagcca
     8221 ttccaaatca gatcaatcgt tccttttgtc aattcagctt ctttcaaatc ccaatcaatc
     8281 ggttgccaat ttaccgtgat tccgtatttt tcaaaaacag ctgtagctaa atcaatatca
     8341 aatcctgcat aagaaccatc tttctgagca aatcccattg gaacaaaagt actatcaaat
     8401 ccaatagtaa tagacttgtt agactggtac tttgaccaat tatctccact agtttcgcta
     8461 gaatttttcc cacaagctac taagaacaaa gcagtcatca gactgactaa tacaagcatc
     8521 cattttttca tccatttttc ctcctattta ggttctactt tcaataatac atctgcgata
     8581 ttttcagcaa actgcaaatc atgggtaacc acaatctggg tcatcccaag ttccctattt
     8641 tgcaagatta gcttctccac ttccaaacgt aattctggat ccagggcaga agttggttca
     8701 tcgtagccaa tgatttctgg gtcaatcatc atagcacgcg ccaaagccac ccgctgcttt
     8761 tgcccaccag atagtgagaa aggataggcc tctgcgtgtc ctcctagtcc taactgttcc
     8821 aagagtccac tcgccttctt ctcagcctct tcctgcttca ttcccatggt cttcacaggc
     8881 gataaagtca aattttccag aactgataga tgaggaaata gttgaaaatc ttggaagaca
     8941 aatcctagta ggttgcgctt ctgcaattca tccagctcta aaggttgtcc attataaaag
     9001 atttgccctg aatcaatggt ttcaagaccc gcaagcatac gtaaaagagt cgtcttacct
     9061 ccaccagaag gtccaacgat agccaggatt tgcttttcag gaatacttag actgaaatta
     9121 gacaggattt gtttgtctcc aaagacttta ttgatatttc gtaattctaa catggcagcc
     9181 tcctatctat aataactata cttcttctca acttttttgg aaataattgt cacaatccca
     9241 atcaaaatca aataaatggc tcctgccaag aacataggaa ctagactagc atcgcggtta
     9301 gcagctgttc gactagccaa gataaggtct gaaattccga gagcatagac caaagaagta
     9361 tccttgacca aactcataac ttcattaaag acactaggaa gaacgatctt ggtcacttgg
     9421 ggcaagataa tatagcgcac tctgtcaaaa gggctaaact tcaagacctt ggcggcctca
     9481 tactgtcctc ttggaatagt gtcaattccc ccacggaaaa tttctgcaaa gtaagctgca
     9541 tagttgagaa caaaggcaat aatagctgca ggaaggcggt ctaaacgaat cccaatactt
     9601 gggagcacat aatagataaa aattagttgc aagagtaagg gggttcctcg cataacccag
     9661 atgtaaatgt taatcagata atggaggggc ttccaatgga cttgcaaggc aaaagcaatc
     9721 aaaacgccca agggaatcga aaatagcaag accagtgcaa agacctgtac agtcgtgctc
     9781 gcaccattca gtaaactcgg taatatctca aataaataag acatactgca cctcctaaaa
     9841 gtaattgttc ctattatagc atgaataaac aagattacca agtatttttg taaaaagatt
     9901 ctaccatata caaataaaaa ccgtagctat caaaagagat aaactacagt tctatatgtt
     9961 taaacattct tacaatctct caaacagttc ttgcatttgc acatcatctg gaaccagttt
    10021 taagtaagtg tgagcatgga cttttgcttc ttcaaaatgt cccaattcac gcaagagata
    10081 gatatagtgt tccagaaatt ctggattgtc cttcaaatct cctgtcaact cttgataatg
    10141 ctcataagca gtatccaaat cgtccatttc ttgataagaa cgagcaatca tccacttggt
    10201 caaaagattt tctggctcct cactctgcaa gtctagaata tcctcataac gctcctgctc
    10261 cagataaata gtggctaaac gaagcaagat ttcttctgta tcctcagcgt cttcttttgc
    10321 agcaagaaga taattttctg caccactagc atcatgcaat tcataagaaa attgtgaagc
    10381 agctagcaag aggcgagttt caaagggatt tttctctaat ccttgcttag cgatacgcag
    10441 ggcttcttga acttgatgtt ccttatgtaa agcctgactg tacccatact catagccttc
    10501 aaagtcagga gaaatggtat caagctgctt aaagtagagg gtggcttttt gatattcttc
    10561 ttgatcaaaa taaagactgg ccaactcaaa agctgttaag tcatcgtatt ctaactccag
    10621 ggctttttct aaaaactcag tagccgtttc aaatttccct aactgagcat aggcaaagcc
    10681 aattcgttga taggtggaaa tgcccgtttg ctcataaatc gagcgattat ctaactgggc
    10741 ataggcttga atagccgctt ggtaattttc caactcacta tccaactctg ccaaacccaa
    10801 catcaagaga gaatcctctg agtaggtcaa ggcctccaat aatttctcac gtgccacatc
    10861 tgtcaaacct tccagctggt aaaggtctgc cttcaaaacc aaagacgaga cataccagtc
    10921 actgtcagct tggatttcct caagataggt aaaggcttct tctatttgac catcctcgct
    10981 agcaattgca gctagattaa gatgaacctc tggaaaatcc tctacaattt tcaggtaaat
    11041 ttccttggcc tgaggataga aaccaatccc ttcaagataa gttgccaact catacagaag
    11101 atcacttgaa tcattttcta aagctttggc gaaataatac tcagccttag ttaaatcttg
    11161 ctcctccaaa gcctgtaaca tctgttgact attgttcact cttgacttcc tcaccctcta
    11221 attcatatag accactgact accttatacc attcgaaaat ggctgaaatg acaaccttag
    11281 cagaggcata aaccggaata ccaagtaaaa ctccccagat accaaacata gatcctgaag
    11341 ttaacaaaac aaagagaaca ttaatagggt ggatgtttaa ttgacttccc aaaatcaatg
    11401 gagagacaaa acggccttca atagtttgtt ctacgataaa gacaatcact actttcaaaa
    11461 gcatgactgg accagcaatc aaacccaata ctagagcagg aagcatggct agaaagctac
    11521 caagataagg gaccagattt aaaataccag cagtaacccc cagcgtaacc gcatagcgta
    11581 gaccaataat cttgaagaag atgataaata ttactgctac aataatagcc actgtcactt
    11641 gccctcgaac atagttggac aactgttgat tcacatctga taaaacttgt ccaacaggtt
    11701 ccttcaattt tcttggaatg aattgggtca aatagttacg caagcctttc ccatcacgca
    11761 agagataaaa gagcatgaaa ggaacgataa tcaaggcaac aatcacttga gaagctccac
    11821 taataaaggc actcacccag ttgactgcct gagatgaaac cttacttgcc aaaactgtag
    11881 cctggctaga aaaattggtc aaaacttgct ctaattgagg tctgaaatca tctggcaggt
    11941 gctgggctac caatccatta acaatcctat ctatatcttc taagtaaaca ggaacgtttc
    12001 ttgcaaaggt caaaacctga cgttgcagat ttggaatggc gactgccaag ccccaaatga
    12061 taaagagagc gatgataaca aagacaatag tgatagctat aacacgatta accttatgct
    12121 tctccatcca atcaacaata ggattcaaca aataatataa caaaccagac aaaatgactg
    12181 gcaacatcac aactgctaaa aaatctaaaa caggtgaaaa tagaaaacta atcttactta
    12241 aaataaaaag attcaatccc aataataagg ttactaaaaa taccgtaatt gccttgttat
    12301 ctaaaaacca cttgaaaaac caagataggc taaaatgttt ctctttttgc tccataaata
    12361 cttcctttct attgttctct cattatacca tttttgaaac aaaataactc ttttttaaag
    12421 tgcttacatc taattgaatg tctttaattt gcttgttttt gtgatataat agtcttatct
    12481 ttacacagag gtatagtaat gaaagaaact gtttattttg gaacttatac acgtcgtact
    12541 tctcaaggga tttacaaggc agactttgat acagaaactg gtcagctttc aaatctagaa
    12601 ctttttgcag ctgagccaag tccaacctac cttgcctttg accagcacca acatttatac
    12661 actgttggta gccaagacga taagggggga attgcagcct atcaaactga cgggactgtg
    12721 ttaaatcatg ttgttgaaga aggagctccc cactgttatg ttgctgtcga tgaaaagcgt
    12781 gatttggttt acgcagccaa ctatcacaag ggacaagtcc ttgtttataa acgccaggaa
    12841 gatggtagtc ttctacttag tgatatggat caacacagtg gccaaggtcc acatgaaaat
    12901 caagcttccc cccatgttca ctatacagat ttaacacctg accactatct agtgacctgc
    12961 gacttgggaa ctgaccaagt catcacctat gacctcgatc aagaaggaaa attatctaag
    13021 ctctatacct atcacagcaa gccaggagca ggctcacgcc atatcatttt ccataaccac
    13081 tataaaatcg cttatctcat ttgtgaactc aatagtacta tcgaagtttt aatctacgat
    13141 ggcgttggcg aatttgtacg tatgcaggtt atttcaactt taccagaagc ttacgaaggc
    13201 tttaatggaa ccgctgctat tcatctctct aaagacggta aatacctcta cgcttctaac
    13261 cgtggccatg attctatcgc agtatatacc atccttgcgg acggtagctt agagttatta
    13321 gaaatcgttc caacgcatgg tcagactcca cgtgattttg atttgacacc cgaccaaaaa
    13381 tttctcattg ttgtccatca agactctgac aatgcaactg tctttaaacg taattgtgac
    13441 aatggtcgtc tagcagaact ctccaacgaa ttccatgttc ccgaagcagt ctgcatccgt
    13501 tttgctcctt aaaacaccat aaaaaatggc tctataatat ttgtagtggg taaatcccct
    13561 atggatatta tggagcctat ttttgtgtag aaaaaaagtc ccataagatc tataatgaaa
    13621 agcgatcaaa caactcatta gaaa
//
LOCUS       DBEJJV010000051        13035 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.051, whole genome shotgun sequence.
ACCESSION   DBEJJV010000051 DBEJJV010000000
VERSION     DBEJJV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 13035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.051"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(98..610)
                     /locus_tag="ACL3GT_001849"
     CDS             complement(98..610)
                     /locus_tag="ACL3GT_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-activated cytolysin C-terminal
                     domain-containing protein"
                     /protein_id="HGR0517459.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNFPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(635..1210)
                     /locus_tag="ACL3GT_001850"
     CDS             complement(635..1210)
                     /locus_tag="ACL3GT_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HGR0517460.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            complement(1220..1615)
                     /locus_tag="ACL3GT_001851"
     CDS             complement(1220..1615)
                     /locus_tag="ACL3GT_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase family protein"
                     /protein_id="HGR0517461.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            complement(2091..2900)
                     /locus_tag="ACL3GT_001852"
     CDS             complement(2091..2900)
                     /locus_tag="ACL3GT_001852"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0517462.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(2897..3457)
                     /locus_tag="ACL3GT_001853"
                     /pseudo
     CDS             complement(2897..3457)
                     /locus_tag="ACL3GT_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            complement(3459..4670)
                     /locus_tag="ACL3GT_001854"
     CDS             complement(3459..4670)
                     /locus_tag="ACL3GT_001854"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019318858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HGR0517463.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(4684..5367)
                     /gene="rpiA"
                     /locus_tag="ACL3GT_001855"
     CDS             complement(4684..5367)
                     /gene="rpiA"
                     /locus_tag="ACL3GT_001855"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HGR0517464.1"
                     /translation="MENLKKMAGIKAAEFVKDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQIIAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(5665..6504)
                     /locus_tag="ACL3GT_001856"
     CDS             complement(5665..6504)
                     /locus_tag="ACL3GT_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HGR0517465.1"
                     /translation="MKVIDQALLEKVIIERSRTSHKGDYGRLLFLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDAFGEDLVKQVFAGLRQNQILIVDGGALTILARTSLSFSSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASALTSFPQGTILVEKGSATRIWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFAGQFKQASLYERVAVATHLHSAIAQELAQEQYVVLPTEISNCLPKVMK
                     RYV"
     gene            complement(6518..7339)
                     /locus_tag="ACL3GT_001857"
     CDS             complement(6518..7339)
                     /locus_tag="ACL3GT_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HGR0517466.1"
                     /translation="MILKIYNREYSLQWDGIYYLALIDYPNIQEWELEKIAKFIAYEK
                     LHKRQTSIECADSCLKKEILDYICQHPFLPPFTPTDKRVASTYDLHKRLVTSDYCSHT
                     TTIDAAISIFKTGQLLSAVKAFRRDAEELVLDSRNAASDPIDYFDYVMLGWSNTSSGY
                     RLAMERLLGRAPSEKELQDKFIPGVSFHFIYTDLIKVTGYIFDGYHVAKIKDMLNLFS
                     ELYICIIPTHNKSQFENIIPTKIQDRVHYLDYAGEDLEEWTKKVYQVVLKQSDKG"
     gene            complement(7476..8333)
                     /locus_tag="ACL3GT_001858"
     CDS             complement(7476..8333)
                     /locus_tag="ACL3GT_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HGR0517467.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIELEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(8487..9221)
                     /locus_tag="ACL3GT_001859"
     CDS             complement(8487..9221)
                     /locus_tag="ACL3GT_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HGR0517468.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(9221..9904)
                     /locus_tag="ACL3GT_001860"
     CDS             complement(9221..9904)
                     /locus_tag="ACL3GT_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HGR0517469.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRLKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            10094..10324
                     /locus_tag="ACL3GT_001861"
     CDS             10094..10324
                     /locus_tag="ACL3GT_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HGR0517470.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            10553..12811
                     /locus_tag="ACL3GT_001862"
     CDS             10553..12811
                     /locus_tag="ACL3GT_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HGR0517471.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
BASE COUNT         3914 a         2935 c         2332 g         3854 t
ORIGIN      
        1 aattttgttc tttcacagag agctacctga gttctattca agctcagata gtactttctt
       61 ataaactaga caaactaact gtcattgtac catcagatta caagacatca tcgtcactca
      121 ccttggaatt caatgtcgta ccccaatggg taattttacg gtggggttga gctaaaattg
      181 gtctgttttc atagattgtt tgccatctat tccatagtag gcccgtcttt ttctcaatct
      241 taactcgcag atttctcata ttttctttga ttgggaagtt gaggacaaaa cctgcagtct
      301 ggttgcaacc gtttccttcc caagaatgac tacgaacaac ttggtttcca tctttatcta
      361 ctggaacttc ttcccaagtt atggagtagc gggcaatgta agctccactg tgttgaattg
      421 tcaatgtttt atctttcaca ggagtctgac tgattggttg aactggctta gaaacttgtg
      481 tcgccgtttc agcattcgta gctataaagc ggaaaacttc aacttctgca agactgaggg
      541 cattatagcc ttctagccca atccgaacat agcgcgcttt tttatggtta atcgtaattt
      601 gtgctgacac atctttagga gatattatac gttttcactc aatttcttta ccagaactgt
      661 ctaaaagaat gacatcaaag tttgccaatc tatcctgggc agtgtctgtt cggttgtaaa
      721 tattgatttg gcgaatggtt tcttctttag ccaaatctac ttgccaccaa ggcttagatt
      781 ggaagtttgt atgagtgaca gaattgtgac catagttacc atcgactttg ccatccacag
      841 ctcttctagc atctcctccg aaagctgtcg aactttgagt aacctgtttt cctaaggcaa
      901 tattttccat tggttcagcg cttggttgac tagaagattg aggtagagcc tgtttcttaa
      961 agaatcgcac tttatccaat ttcggatcac gataaccatg tttatccaag gtagcttgtt
     1021 taccaatatt aaagttagga atatcattca ttggactttc aaaatagcca cgagaacggt
     1081 gtttaaagcg tgaattacct gtaaatgtaa caatatcacg attattatga atcaagggag
     1141 tcacaacatt gtcattatca accacataat gcttaatttt tccactaaca gctaatttac
     1201 gactttccaa accaacatct cagaaaccat tcttagcatc ccaaacagtt ctggaagtaa
     1261 tcactttagg agcactgaaa gttgtcactt tcctcaatac atggttataa aaatcaggat
     1321 atttttggta atcttcaacc gctgcaatct gagctaggta gcctccaaga gaatgacctg
     1381 tcatatacaa cttagtaata cttatatcct tggctaattc cccaacaacc ttgcggatgt
     1441 catccgcttg agctggctct gttatctcta cttttgactc ttcccttttg ttttcaagaa
     1501 cttcacttgc ttccggaagc gtttgaggag ctagtcttgg ctcctctcta agaggagttt
     1561 ctagttttgg agcatcattt tctgactctt tcaattcctc cttagaatct agcacaccta
     1621 ttaccacttc agttgttaca tcttgcttta cttcattggc tgaaattcca gctggagcta
     1681 gaaatcaaag ccgactacaa cagatacaac tccgatactt aattttttat gccaaagcgc
     1741 ataattcgtt gaccaatttt cattatttct tatctttctt ttcgtttatt tacaagcaga
     1801 ctcaagcgaa atctcattgt gctatatatg ataagactga gaaattcaga aagtcaattc
     1861 attctcatct ctccttatca tactagtctg cttggctagg aagctaatgc tagtatccta
     1921 gaatcttgtc tttcacaatg ctggctatca gatcagacac acctattctt ccgcttcttt
     1981 cagttataag agcaggaaga agctcatagt attcctctgt ttcttcttta atacggatag
     2041 gcagtcaatc ctgaaaagac agaggcactc ccccttttaa atcttttttc ttacaattca
     2101 gcaagaatcg ctttaagcaa gcctttaaaa tcacctttaa cacgttcagt cacttctaca
     2161 acttcttcgt gattgagttc ttcttggaaa ccagccgcaa agttagtgat acatgaaatt
     2221 cccagaactt tcaagccaga gtgggctgcc acgataactt caggaaccgt agacatacca
     2281 actgcatctg ctcccagtgt cttataggaa cgaatttctg ctggtgtttc ataagtcgga
     2341 ccagtaactc cgatatagac accttcatca agcttgatat taagtttttt agccacttca
     2401 tgggcagtag cacggtattc tggtgtgtag gccctagaca tatctgggaa acgtgggcca
     2461 aagtcatcca agttttcacc catcaatgga ttttgccccg tcatgttgat atggtctgag
     2521 atagccatca aggtaccagg accaaatccg ataccgccag ctgcattggt tacaataaca
     2581 ccttcacatc caagaacttt catcacacga actgggaaag tcaccacttc cagaggattc
     2641 ccttcataga aatggaaacg cccttgaaga gccaagacct tgcgacctgc cagttcacca
     2701 tataccaatt taccagcatg accgactact gttgaacggc cccagtttgg aatctcagca
     2761 tagtctacta caactggatt ttcgatttct tctgccaatt ctccaagtcc tgacccaagg
     2821 attagaccga actcaggggc tgcaattccc ttttctttca ggaaagtagc agtttcatgg
     2881 attttgttta aaaatgtcat tgtgtgtctc ctttattatt tttttagcat ttgaccaatt
     2941 ttgtcaaagg ttttagcatt acgaatagta atgtggcggt agaaaggcac ctcagcaagt
     3001 acttatgata ggcagtctta gaataggatt cttcagaaaa tttcccctag aaaatcccaa
     3061 gttttccaaa ataaagcact tcatctttca gctctaaact ttcaactgtc gcgatgactt
     3121 ggtccacatc caaaccctca gtgtaaaaga gaaaatcttt tcgtgccaaa tctctgctcc
     3181 accaagctgg tagattttca agttccgcct caaagtcctc tagactcagt aaagaaaagc
     3241 tctgaataaa tggataatgg actgcaaaga aagtctctag cttttcaacc aattgggctt
     3301 tggaatctat cgaagtaaag aaaatattgc cactgttgat gtagctctca accttttcca
     3361 gtcccaagtt tgtcaattct tgacgaagct ccgccatgac gaccttattc ttaccaccaa
     3421 cattgatacc tctcaccagc aaagcatagc gcgtcatctt ataccaattt atctaagaaa
     3481 ctttccccaa tcatagcagt ttccacacca aagttatcgg caacagtcgc tgaaatatct
     3541 gcaaaatgtc ctactggaat gagaccattt cctttaaagg cagggctata ggccaacaat
     3601 ggaatatatt cccgagtgtg atccgttcct gcatacgttg ggtcatttcc atggtccgca
     3661 gtaatcaaga gaaggtcatt ctctctcata gctgcgataa tttcaggtaa gcgttcatca
     3721 aactcatgca agcaatcacg gtaaccgtga gcattacgac gatggccgta aagggcatca
     3781 aagtcaacta ggtttgtgaa tgagaatcct ttttcaaact cagcaagtcc catagtcttc
     3841 aatagtgtat caattccatg actatttgac ttgttgtgac ccatgtcatg gttgatacca
     3901 gcaccgttaa agatatcgtt gattttaccc acagcataag tatcgatacc agcctcattc
     3961 aatttatcca aaacagttgg ggaaaatgga gatacagcca agtcacgacg gtttgccgta
     4021 cgagtgaagt tacctggttc acctacataa gggcgagcaa tgatgcgacc aagaagggca
     4081 ggacgctcaa gggtaatcga acgagcgtat tcacagatac ggtacaattc atccaaagga
     4141 ataatgtctt cgtgggcagc aatctgcaaa acagggtcag ctgaagtata gataatcaac
     4201 tctccagttt ccatctgacg tggtccaaaa tcatcgataa cagccgttcc tgaataaggt
     4261 ttgttggctt cacgaataac cttgcgtcct gagaattctt cgatttttgt caggatttct
     4321 tctgggaatc cgttccagaa agtatcgaaa ggctcagtaa tgttgagtcc catgatttcc
     4381 cagtgtccag tcatagtatc cttaccaaga gatacttcct ctaattttgt tgcatatcca
     4441 gttggattgc tttcagctgc tacagtctta agaggagttt cacgaggaat atttccaaga
     4501 cctattttag ccatgtttgg gacattcaaa ccaactgttt ttgaaatgtg tcccagtgtg
     4561 tcagaagctc catctggaac ccctgcattg acaaagttat tagcatctgg tgctgcaccg
     4621 attcctacag aatccagtac caccaaatga atacgattaa atttagacat cttatgcccc
     4681 cttctatttt cctttttttg aagttgaaat ctgaactcca tcccgtccag caacgatgac
     4741 cttatccacc atttggttga ataaaccatg ctccacaaca ccaacgacat ggtccaattc
     4801 ttgtccaaaa gcaattggat tttcaatgac atccaaggcg aggtcaatga taaaattctg
     4861 catatccgtc acaaaacgtt ggccgtcttt ttcacggaaa cttggtttgt agccagctcg
     4921 ttcaaaacga cgaaagacct gttctgcacc atactgaacc acttctactg gcaatttaaa
     4981 agcacctagt ttttcgacca gcttgctttc atccaccacc caaatgtatt cttttgatgg
     5041 tgtcgcaaca accttctcca tcagaagagc accaccacca cctttgattc cattaaactg
     5101 actatccact tcatctgcgc catcaactgt cacatcgaca aagtctactt ggtcaataga
     5161 tttgagtggg atattaaggc cttctgcctg tttagtggtc acactagaag tcgttacagc
     5221 tataatctgc aatccttctt ccttgatacg acgaccgatt tcttcgacaa aataataggc
     5281 agtcgagcct gttccaagtc caacgaccat tccatccttg acaaactcag cagccttgat
     5341 acctgccatt ttcttcagat tttccactca aacacctcca ttaaagagct acctctatta
     5401 taccatgtaa aggcttttat ttcatctaaa agtaccttta gaatactgct tatttatcct
     5461 tgaaattaaa tttttttaat aaaagcagaa ctctgacaaa tcactttaag tacggatgta
     5521 aaccaaatca actctaacaa aaatagattt acaagagtaa aaaaacgaac aaatttagtt
     5581 tcttagcgag aagaatacta aacgttcgtt ttttgtgaat taagaataat gatacaaatt
     5641 atcaatattt tttgtctaac tattttagac atatcttttc attactttag gaagacaatt
     5701 actaatctcc gttggcaaaa ccacatactg ttcttgagct agttcttggg ctatggctga
     5761 atgaagatgg gtcgctactg ccacacgttc gtaaagacta gcttgcttaa actggcctgc
     5821 aaatcctgca atcatcccag caagcgtatc tcccattccc ccagtcgcct gatagggacc
     5881 gccaacctgt aactggtaat aatctgattg gccagcttgc caaatacgag tagctgaacc
     5941 tttctccacc aaaattgttc cttgagggaa ggaagttagg gcactagccg ttgcatcttc
     6001 cttttgcttt tcaatcgtaa ttccagataa tttttcccat tctttttggt gaggagttag
     6061 gataagctgg cttgaggaaa atgacaaact tgtcctagca agaatggtca aggcacctcc
     6121 gtctacaatc aaaatctgat tttgtcttaa gccagcaaag acctgtttaa ctagatcttc
     6181 tccaaaagca tcgtctcgta aacccggccc cagcaagaca acttctgcct tctccaattg
     6241 ctcttttaac aactgctggt cttgaagaga aaaggccata gcctcaggta aatggctgtg
     6301 cagggctgga atattttccc tatctgttcc aacggtcacc aatcctgcac cgctttttac
     6361 agctgccaaa gcagccatga tgatggcacc accataagga taagttccac caagaaacag
     6421 cagacggcca tagtctcctt tatgactagt acgagaacgt tcaataataa ctttttctag
     6481 taaggcttga tcaatcactt tcatcgttct tcctcaacta tcctttatct gattgtttta
     6541 aaacaacttg atagactttc ttagtccact cttctaagtc ttctccagca tagtcaagat
     6601 aatgcaccct atcttgtatt ttagttggaa taatattttc aaattggctc ttattatgag
     6661 ttggaataat acaaatatac aactcactaa ataaattcaa catgtcctta atttttgcaa
     6721 catggtagcc atcaaaaata taaccagtaa ctttaatcaa atctgtatag ataaaatgaa
     6781 aactcactcc aggaataaac ttgtcttgta attctttctc tgaaggagct cgacctaata
     6841 aacgctccat cgctaatcga taaccagaac ttgtatttga ccaccctaac atgacataat
     6901 caaaataatc tatcggatcc gatgcagcat ttctactatc caaaaccaac tcttcagcat
     6961 ctcgcctaaa ggctttcaca gcagataaga gctgacctgt tttaaagata gaaatcgctg
     7021 catctatagt cgtagtatga ctacagtagt ctgaagtcac taacctctta tgtagatcat
     7081 aagtcgaggc tactctttta tctgtagggg taaatggtgg cagaaaggga tgctgacaga
     7141 tgtaatctaa aatttctttt tttaaacaag aatcagcaca ctcaatactt gtttgacgtt
     7201 tatgaagttt ttcgtaagct ataaatttag caattttttc taattcccac tcttgaatat
     7261 ttggataatc aattagtgct aggtagtata ttccatccca ttgtaaacta tattccctat
     7321 tataaatttt taaaatcatc taatcacctc actccattat acaacaaaaa ggaggcgcag
     7381 acctcctttt gtaatcttat atctaaaatt taatattcat ttctgccatt ttaaatatag
     7441 ctatagaaaa tacactctct tcagcgattt ttctcttatt ttctatccaa tgtccgaagt
     7501 gctgcttgat aagtttgctc catcagcata gtaatggtca tagggccgac acctccaggg
     7561 actggcgtaa tatagctagc aagtggggca actgcctcat aatccacatc cccacagagc
     7621 ttaccatttt catcacgatt catcccaacg tcaatgacta ccgcacctgg tttgacaaag
     7681 tcagcagtca caaacttggc acgaccgatt gcgaccacca gaatatctgc tttagcagcc
     7741 accttagcaa gattatgggt gcgtgagtgg gtcaaagtca ctgttgcatt cttggccaaa
     7801 agaagctgag ccatgggttt tccaacgata ttagaacgac cgatgacaac cgcattttta
     7861 ccttctaatt caatcccata ttcatgaaac atttccataa ttcctgcagg tgttgatgga
     7921 atcatgactg gatgtccaga ccaaaggcgt cccatattta gaggatggaa accatccaca
     7981 tccttttctg ggtcaatagc caatagaacc gcctcttcat caatgtgttt tggtaatggc
     8041 aactgaacca aaatcccatg ccaagctgga tcctgattgt atttagcaat caggtctaac
     8101 aattcctctt gagtaatggt ctctggaact cgcactactt cgctacggga accagccgca
     8161 agagctgacc tctccttgtt gcgaacgtag acttggctgg ctggattatc cccaaccaaa
     8221 atcactacca aaccaggcac tagagctgtt tcttccttta attttgcagt cttttcagcc
     8281 aactgcccct gcaatttggc cgctaaagct ttcccatcaa taatctgtgt catatcactt
     8341 ctcttttctt tcaaatatct tccattatac caaaaactgc tagtgccctc taacacttct
     8401 ttcctaggtt atcctatagt ttcaaactat aagaaaaagc tctggttgaa cttttcacta
     8461 atcttgtctt gaaattttaa aatagattat aaaaccttac tcaagaaatc tttagtccgt
     8521 tgttcttggg tttgttcaaa aatctgctca ggtgtcccat cttcaacaac cacaccgtct
     8581 gccataaaga taacacgatc tgccacctca cgggcaaatc ccatctcatg tgttacgata
     8641 accatagtca tccctgactt ggcaaggtct tgcataacag ccaatacctc acctaccatt
     8701 tcaggatcca aggctgaagt tggttcgtca aagagcaaaa catctggttc catagccaac
     8761 ccacgcgcga tggcaatccg ttgttgctgc ccacccgaca gactctgtgg ataagcgtct
     8821 gccttatctg gcaaaccaac tttttccaaa agctcttggg ctctcttctc agcaacttcc
     8881 ctgctttcac ctttagtctt gataggtgac aaggtaatat tttccatcac agtcatatta
     8941 ggaaagaggt taaattgttg gaaaaccatg cccatcttct cacgcatggc aaacaggtca
     9001 ttcttcttgt ccgtaatatc gactccctca aagataagct tccccttggt tgcttcctcc
     9061 aacaaattca tagagcgaag caaggtagat ttcccactcc ctgaaggacc gatgataacg
     9121 acaacttctc ctcttttaat ctcgaggttg atgcccttca atacttcatt ctttccaaaa
     9181 gatttatgta aattttcaat ttttatcaag gtttctgtca ttatttctta tctccttgtc
     9241 ccatatgttt ttcaaaagct ttcaaggcta ctgtcagaat agaggtcata atcaagtagt
     9301 aaaatgctgc aaataaaagt ggtgttaaag gtagataggt tgttgtagaa actgttgtag
     9361 ccccattcca caactccatg accccaatag ctgataagag ggagctgtcc ttgataatgg
     9421 tgataaattc gttccccaat gctggcaaga tatttttgac tgcttgtggc aaaatcacat
     9481 aacgcatcgc atttttaaga cgaatcccta gcgaataagc cgcctctagc tgaccttttg
     9541 gaaccgcatt gattccggca cgaacagtct ccgaaacata agcaccacta ttcatagaga
     9601 taatcaaaat ccctggaatc agacgcgaaa aatcaacacc taaaattcca atctgaatag
     9661 tcggagcatt gatatgcata agagcaaagg caatcataat ttgaaccatc atcggtgtcc
     9721 cacggaaaat ccaaacgtac aagttggcca accaaacaag cggtttaaac tttgaacgtt
     9781 gcccaaaagc caagacaaca cccaaaatag ttcccaaaaa gataacacag atagaaataa
     9841 gaatcgtcac aacagcccca tagttaaaat aaggtaaata cttaggtaaa aaagaaaaat
     9901 tcatagtcac actgctttct aaaatagaat actgtatgat tataacatgt tttgaattaa
     9961 aatttaaatt ttttatccaa tttatttaaa aatctttaaa ctagcagaat tagcgagaaa
    10021 tcttagtttt ttctagtcaa gttgccctcc tttatggtaa aatagtaacg ataagaaatg
    10081 aaggagaatc aaaatggaat cacatttggt tagaatcatc aaccgccttg aagcaatggc
    10141 aaacgatggc ggaaatttaa aacgtaattt tgaacgcgaa ggagttgttg ttgcagaagt
    10201 tgcgtacagc cacgacgaag aaaacggccc aatctttacc cttcgtgacg tagaagatcg
    10261 cgaaacgtat acgtttgata gcattgactt aatcgcaatg gaaatttacg aacttctcta
    10321 ctaatctaaa acaagttggg attgtccctg catgtctaag taaaatcctt tttgtctcac
    10381 aaataggatt tttttatagt ccaaattcac aaaaattttc attgtaacaa cttctcaaag
    10441 cttcaatctt tttacttgct ttacacccca atcctgttat aatgagagta tagaatttga
    10501 ctatttttga cctttaaaca agtcaggcta aagaaagaaa tgaggtagat gtatgctttg
    10561 tcaaaactgt aaaattaacg actcaacaat tcatctttac accaatctca atggaaaaca
    10621 aaaacaaatt gacctctgtc aaaactgcta taagattatc aaaacagatc ctaacaatag
    10681 cctcttcaaa ggtatgacgg atctgaacaa tcgtgacttc gatccctttg gtgatttctt
    10741 caatgatcta aacaatttca gaccttctag caatactcct cctattcccc caacccaatc
    10801 aggtggaggt tacggtggaa acggcggtta tggttcccaa aatcgtggat ctgctcaaac
    10861 tccgccacct agccaagaaa aaggcctgct ggaagaattt ggtattaatg taactgaaat
    10921 tgcccgtcgt ggagacattg accccgttat tgggcgcgac gatgagatta tccgtgtcat
    10981 cgagattctc aatcgtagaa ccaagaataa tcctgtcctt atcggtgaac ctggtgtcgg
    11041 aaaaacggcc gttgtcgaag gtctagctca gaaaattgtc gatggcgatg tgccacataa
    11101 actccaaggt aaacaagtca tccgtctgga tgtggttagc ttagttcaag gaacggggat
    11161 tcgaggacaa tttgaagaac gcatgcaaaa actcatggaa gaaattcgca aacgtgaaga
    11221 catcatcctc tttatcgatg aaatccatga aattgttggt gctggttctg cgagtgatgg
    11281 taatatggac gcaggaaata tcctcaagcc agcccttgct cgtggagaac tgcaactagt
    11341 cggtgctact accctcaatg aataccgtat cattgaaaag gatgctgccc tcgagcgtcg
    11401 tatgcagcct gttaaagtcg atgaaccaac ggtggatgaa acaatcacta ttctcaaagg
    11461 gattcaaaag aaatacgaag attaccacca cgttcaatat accgatgctg cgattgaagc
    11521 agctgcaact ctttccaatc gctacatcca agatcgcttc ttgcctgaca aggccattga
    11581 cctcctagat gaagctggtt ctaagatgaa cttgaccttg aattttgtgg atcctaaagt
    11641 aattgatcag cgcttgattg aggctgaaaa tctcaagtct caagctacac gagaagaaga
    11701 ttttgagaag gcggcctact tccgcgacca gattgccaag tataaggaaa tgcaaaagaa
    11761 aaagatcaca gaccaggata ctcctatcat cagcgagaaa actattgagc acattatcga
    11821 gcagaaaacc aatatccctg ttggtgattt gaaagagaaa gaacaatctc aactcatcca
    11881 tctagccgaa gatctcaagt ctcatgttat tggccaagat gatgcagtcg ataagattgc
    11941 caaggctatt cgccgtaatc gtgtcggact tggtacccct aaccgcccaa tcggaagctt
    12001 cctcttcgtt ggaccaactg gtgtcggtaa gacagaactt tccaaacaac tggctatcga
    12061 actttttggt tctgctgata gtatgattcg ctttgatatg agtgaataca tggaaaaaca
    12121 tagtgtggct aagttggtcg gcgctcctcc aggttatgtt ggctatgatg aggctggtca
    12181 attaactgaa aaagttcgcc acaatccgta ttctctcatc cttctcgatg aagtggaaaa
    12241 agctcaccca gatgttatgc acatgtttct tcaagtcttg gacgatggtc gtttgacaga
    12301 cgggcaagga cgcaccgtta gcttcaagga tgccatcatt atcatgacct caaatgcagg
    12361 tacaggaaag accgaagcta gcgttggatt tggtgctgct agagaaggac gtaccaattc
    12421 tgtcctcggt gaactcggta acttctttag cccagagttt atgaaccgtt ttgatggcat
    12481 tatcgaattt aaggctctca gcaaggataa cctccttcag attgtcgagc tcatgctagc
    12541 agatgttaac aagcgcctct ctagcaacaa cattcgtttg gatgtaactg acaaggtcaa
    12601 ggaaaagttg gttgacctag gttatgatcc aaaaatggga gcacgcccac ttcgtcggac
    12661 tattcaagac tatattgagg acacaatcac tgactactac cttgaaaatc caagcgaaaa
    12721 agatctcaaa gcagttatga ctagcaaggg aaacattcag attaaatctg ccaaaaaagc
    12781 tgaagttaaa agttctgaaa aagaaaaata aatcctatag aaaaggagta gaaaatgaaa
    12841 tttttctgct tcttttttta ctaaaataac tgtaatttct tgacagcttg ccctttgtcc
    12901 attatgatat atagtagact gaatctgaaa tagtacgaaa caattgctaa aacatttata
    12961 gaaattaatt ttactttccc aatcgatttg ttctcatctt atttcaatct gctatagtca
    13021 attgaaacaa gaaca
//
LOCUS       DBEJJV010000052        12787 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.052, whole genome shotgun sequence.
ACCESSION   DBEJJV010000052 DBEJJV010000000
VERSION     DBEJJV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 12787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12787
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.052"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(415..2142)
                     /gene="ezrA"
                     /locus_tag="ACL3GT_001863"
     CDS             complement(415..2142)
                     /gene="ezrA"
                     /locus_tag="ACL3GT_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HGR0517472.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIDEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLESGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2224..4170)
                     /gene="gyrB"
                     /locus_tag="ACL3GT_001864"
     CDS             complement(2224..4170)
                     /gene="gyrB"
                     /locus_tag="ACL3GT_001864"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HGR0517473.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4185..4748)
                     /locus_tag="ACL3GT_001865"
     CDS             complement(4185..4748)
                     /locus_tag="ACL3GT_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HGR0517474.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4833..5387)
                     /locus_tag="ACL3GT_001866"
     CDS             complement(4833..5387)
                     /locus_tag="ACL3GT_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1 family glyoxalase III"
                     /protein_id="HGR0517475.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5398..6621)
                     /locus_tag="ACL3GT_001867"
     CDS             complement(5398..6621)
                     /locus_tag="ACL3GT_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HGR0517476.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6658..9108)
                     /locus_tag="ACL3GT_001868"
     CDS             complement(6658..9108)
                     /locus_tag="ACL3GT_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HGR0517477.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPFSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPSVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9308..10237)
                     /locus_tag="ACL3GT_001869"
     CDS             complement(9308..10237)
                     /locus_tag="ACL3GT_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HGR0517478.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10377..10664
                     /locus_tag="ACL3GT_001870"
     CDS             10377..10664
                     /locus_tag="ACL3GT_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HGR0517479.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10698..12032)
                     /gene="ciaH"
                     /locus_tag="ACL3GT_001871"
     CDS             complement(10698..12032)
                     /gene="ciaH"
                     /locus_tag="ACL3GT_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HGR0517480.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12022..12696)
                     /gene="ciaR"
                     /locus_tag="ACL3GT_001872"
     CDS             complement(12022..12696)
                     /gene="ciaR"
                     /locus_tag="ACL3GT_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HGR0517481.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
BASE COUNT         3883 a         2732 c         2277 g         3895 t
ORIGIN      
        1 tatttaccgt ggactaaagt tgtacaagaa aagtgcaaat aagaaatctc cagattagga
       61 actatccgtg agttctctag tctggagatt tttcaataga cttcgttatt ggacggttac
      121 caagttactc aaagtacaga tttgaagctg cagataagac tgacgaaatc actttaatac
      181 taaatgaaaa tcaaaaagca aactaagaag ctagcctcag gctgtacttg agtacggtaa
      241 ggcgacgctg acgtgatttg aagagatttt cgaagagtat aaaacactgt tttgaggtgg
      301 tggataaatc ggctgggtaa aaactcaatc tcaggagaaa atgaagtaaa tctccccaca
      361 actatagaaa aagatttgat tctgctcctc acacaataaa atctttttct tttattaaaa
      421 acgaatcgtt tcacgtgttt tctcatatga ggtaacaaag cgattggtta caccaggctc
      481 tgccacttcc aatgcttgag aaatcttgtc aaatgaagcg tgataatcaa attctttttc
      541 aaaaatatct aaagcttcgt taaatgcttc ttgaatgcgt tcatcaaatg agcgatagcg
      601 gttagaatat tgcaagagtt gctctgtcaa agttgcatat tgtacaatat tataagtttc
      661 cgtttctaaa gcttccatat cattcgttgc aatttcaaga actcgggtaa cagattcaat
      721 gttaatcatt ttttgttcta actcaaccat taaatcctcg gtattattgc ttgccgtaaa
      781 gaataacttc aagaaagttt gtggaatacc tggcagattg cgtttttcca tgtatcgctt
      841 gatagtatgg agacgattga cataaacatt ggccttttga cgtgcattaa tatcatcttt
      901 ctcaatttgt gtcaggcgct cactaactga aatttgctca tcttcaatat cttttagttg
      961 agtttgtaaa tcctcaagat tttcttcaag aactgaataa gcttgggttg gttcttcttg
     1021 atttgaagtt acctcaacaa tagctgcctc aaaactctct aattctgtct gaatacgacg
     1081 aacatggctt gcagctgtct caggaagtaa ataggtcttg ttcaaacgtg caatatcttc
     1141 tcccaataaa gtattattct ctttcatatg ttgaaggtaa gttggaagag ttgcaagtag
     1201 attttccact actttctgag cagcaatttc tcgagtaaaa atatcataca aggcattgat
     1261 ttcctcttgt gcctgtccat tctcatattc ggcattatcc aattccaact gacgaatatt
     1321 ctcttggttt ttcttgaatg cttcataaag caagtggaaa cgcgcttcaa tatccgtttc
     1381 aacaaaatga taattagcat caattagttt acgataaccg gattccaaat cctgtaattg
     1441 atctggcaat tctgtagaaa gcgtcgtaac caaggctgga acacgatcca caatatgact
     1501 taaggccaaa atgtgatttt ctgtattatc caaaatcact gcggcttcca cagggtcacc
     1561 cgatgaattc aaggttacaa attgtgaaaa ttcagattgg atattttcta attgtttttc
     1621 aatttcatcc aaggcttgac catactgttc tgaattttca gcaactctat gctgaagttc
     1681 ctcaaataaa tccaaagcat gaagaacacg accactattt ttagattctt gcttctctaa
     1741 gtctgccaaa gcattgcgaa ttgccgcaat atcttcgtca atcaaagtaa tttgactctc
     1801 aatttggtca atttgatgac tggccttgag aaaacgaaat gaatggttat agccttctgc
     1861 ttcaaagaga ttattttcaa tatcggcaaa agagttgaga gataaatcga cccatttttg
     1921 attccattca cggaaagcca cttgactttg tccaatcaag tgcatatttt ttacagcttc
     1981 tacttcatca tttactggaa gattgtatag ttcttctttt ctttcttcta gcgcctctaa
     2041 tctcccctcg tttcgcttac gtagaaagat tgccactaca taagccagaa ctaaaatgac
     2101 tgcaattgca accattaaat aaattagttg tccattagac atatcaaact ccttttttac
     2161 ttgaaacaat cgtaacgatt atatcatatt ttttagacca agggaactac ttctccctat
     2221 tttttagaca tcaagtgtac tatagacagc attttcttcg ataaactcac gacgaggctc
     2281 tactcgatcc cccatcaaca tatcaaagat tttatctgct tctgcagcat catctacaga
     2341 aactctagcc atcaagcgat gttcgggatc catggttgtt tcccacagct gatgatcgtc
     2401 catttcacct agccccttat aacgctgaat agtcggtttg gtacgacctt cactataacg
     2461 ggctaaagct tcttggagtt tgatttcttg atctgcaccc ggctggatat attctttaat
     2521 ctcgcttcca accttgacac catagattgg tggttgggca atataaacat aaccagcttc
     2581 taggattggt ttcatataac gataaatcaa ggttaaaaga agggtacgaa tgtgggctcc
     2641 atcgacatcg gcatcggtca tcaaaacgag tttttggtaa cgggctttcg aaacatcaaa
     2701 ttctgcgcca aatcctgttc ccatggctgt gaaaagacta cgaatttctt cgttagctag
     2761 aatcttatcc atacttgctt tttcaacgtt caaaatctta ccgcgaattg gaaggatagc
     2821 ctgaaactca cggttacgac cagatttggc tgatccacca gctgagtctc cttcgacgat
     2881 gaagagttct gtttcagcag ggttattaga agaacagtct gctagtttcc ctggaaggtt
     2941 ggaaatttcc aaaccagatt ttttacgtgt gacttcacgc gcacgcttgg cagccacacg
     3001 agccttggca gctaaaatcc ctttttccac gatacgtttg gcaatctgtg gattttccat
     3061 gaggaaatcg gagaaggctt cactgaagag gcgattggta atcttgacca cttcgctatt
     3121 tcccaatttg gtcttggttt gtccttcaaa ctgtggattt gggtgtttaa ctgagataac
     3181 tgcagttaat ccttcgcgaa catcttcccc tgttaaatta tcttcattgt ctttcagtaa
     3241 cttattctta cgagcataat cattgataac acgagtcagt gccgtacgga aaccttgttc
     3301 atgcgttcca ccttcatggg tatgaatatt attggcgaaa ctcatgacat tttcatggta
     3361 acctgttgtg tactgcatgg ctacctcaac tgtgatatca tccatctcac cgtctgtata
     3421 gattggtgta tcaaagatta catccttgtt ctcgttgata tattcaacgt aactagcaat
     3481 cccaccttca taatgataat gcttggtttg ttccaaacct tggcgcttat ctgtaattga
     3541 aatttgaaga ccgcgattta gaaaggccaa ctcttgaatc cgtttattta atttatcaaa
     3601 atcaaagatt gttgtttcag tgaaaatttc tgggtccggt gtgaagtgaa ccgttgttcc
     3661 agttctatct gtatccccaa ccacctcaag gtctgcaaca acatgaccac gacggtattc
     3721 ttggtaatga atcttaccgt ttttatggac atgaacgtct aattgagtgg aaagggcatt
     3781 aactactgac gaccccaccc cgtgaagacc acctgaaacc ttgtatccac caccgccgaa
     3841 ctttcctcca gcatgaagga ctgtaaagac ggtctcaaca gcaggacggc ctgttttttc
     3901 ctgaatatcg actgggatac cacgcccatc atccacaaca gtaatcgaat catctggctc
     3961 aataaaaact tgaatatggc tggcaaatcc tgccaaggcc tcgtcaattg agttatcaac
     4021 aatttcccag actagatggt gaagaccttc ttttgaggtt gatccaatgt acatccctgg
     4081 acgcatacga acagcctcta agccctctaa aacttgaatt tgactggcat cataatcctg
     4141 tgcctgcaga tttttgattt cttctgtcat cttattcctt tttcttatat gtctaatact
     4201 tgtcttaaat tcacgatact ggtaaacaag tgggtatcaa gtcctgcagc ttgacctgct
     4261 tcgatatcaa tcggccgatc accaatgaca agaccagagc taatctgata cttttctctt
     4321 aaataaagca tggattcggg atttggcttt ctcttaaagc ctgagctaga agtcaccact
     4381 tctgtaaaat aagctgctat agaggttttt tctaaaattt ccaaaacctg atcatttcga
     4441 tgagagacca aaaaatgacg gccaccttga tttaaaatgt cttccaatag gtcagaaact
     4501 ccttcaaata aaatcgggtg ttcaagctct ctggcttcat tttccttgta cttttctaaa
     4561 aaattctcta aattgggagc gaatgtctca atcgcaaaag gagtagaaac ctttaaagct
     4621 tgatagacac tgtcatggtc ttgtgtgata ccatacagtg ccaatgtttc aacaaatgca
     4681 gctgttgaag tttcataatt atccagtaaa gttccaccta aatcccagat gtaatcgtga
     4741 tatttcatac ccttcattat agcatttttt tatgaaaaaa gcgatgattt ccctgagttt
     4801 tccacataaa aaacgagaga ataactcccg ttttactgat ttttaccaaa gacatctcga
     4861 tagagcattc ctgttcgtaa actctctgcg tcccctccta gttgctccac caactcgtag
     4921 gcaaaggcaa gggctgttga aggaccccga ctggttgtca actgaccatc taccactact
     4981 gtttccttga cgtagtgacc atcaaggatt tgctcttgaa cgccgtcata acaagtgtat
     5041 cgcttatttt tcaatatctc tgcttgattg agggcaattg gtgccgcaca aatggctgct
     5101 agtttcttcc cttcttgctc gaagctttgc aattcttgaa tcaaggtctg attatcacgt
     5161 aaatgtgcag aaccaggcat acctccagga agaacaatca tatcatagtc tgataaatct
     5221 ccatcaaaga catgatctgc tcttacttgg attgcatgcg aacccgttac ttgctcttca
     5281 aaaccaacca tatcacatgt gatattggct cgacgcaaga catctacaac tgtcaaggct
     5341 tcaatttctt caaagccctg agctaacata actgctactt ttaccatgat tttctcctta
     5401 tttaatttgt tttaatacaa cctttttccg tttgaatggg acttttccgc tcttttcttc
     5461 agctaaatta gtctggtaac tcatcgataa aagcaaacca acaccaatca aattactgat
     5521 aatagctgat cccccttgcg aaatgaaagg caagggaatc cccgtcaaag gaagtagtcc
     5581 agtcacagca ccgatattct caaagatgtg gaagagcaac atcataatca aacctgtgga
     5641 aatataagtg tagaactggt tatttgattt aagagtaatc ttcaacatac ggtaaatcaa
     5701 catgagatag agggcaataa ccaggacaga gccaataaag ccaaaatctt ctgcaataac
     5761 cgtaaaaatc atatctgact ctcgaactgg gataagcaga ttcgaagcat taaatccctg
     5821 accaaataag ccaccactcc caatggcaat ctgcccttga gcctgctggt aagtcgttgt
     5881 ttgggcaaac tcaaagggat tgagccaagc caaaatccga ttaatttggt aggtcggcat
     5941 tccaatctgg tgaagaaaag ctcgtccgtc cttgctaata aagatagcta agaaaccagc
     6001 aactcctgtt acagcagtca caaatactgg gataataatt ttccaagaaa cccctgataa
     6061 taaaacgatt cctgagaaaa tggctacaaa aaccaaagcc gtccccaagt cactttgaag
     6121 tgctaaaaga actaggactg gaatggtaaa gagaatcatc cagaaaatta acaaaaagtc
     6181 cagcggaacc gtgcgtctcc attccttatg tttctttgta aattggacaa tgacacgagc
     6241 caacatgagg atataggata tcttcataaa ttctgacggt tgaaataggg taattccatt
     6301 tattgatacc cagtttttgg cacccgttga tgcaactaag cttggattat aaaatacaat
     6361 cggcaagatc ataagtccca agcctaaaat atatagaaag ggggtcacct tccaaagaaa
     6421 ttctgtatta aagagcatga ccacaaaacc aatcacaagc cccaaggcaa tccaggcgac
     6481 ctgctgccct aaaatgggca gaatattatt gggataatca tgactaacgg ctatatagat
     6541 agccaccaca ccgatgacca gtagaaaaaa tactggcaag agcaaactat aatcgactct
     6601 agagtcgaga gaacgtttca tatgtactaa ccttatactt tcatacaata ctatttatca
     6661 aagttcatta aaaaatctat caatagcctc gtcaacttcg gatcgagaga tggttttaac
     6721 agtcgcttct tctgctagag atgctactat ttgtttgccg tatcgttttc cgacgattct
     6781 cctatccaaa ataagagtta aggaacgttg gtattcacgt ctcatacttc ttcccaaagc
     6841 ctgttttaaa cgaataatgg ccattggcaa ttgataatca taaaaggcat ttttcccttc
     6901 ttgattcagt tcttgattaa tctttttcgt caagggttct tgaggatttt ggaaaggaag
     6961 cctcggtaca acttgaatca cagaaggatg gcttgaaaaa tcaactccct cccagaaact
     7021 tgctgcacca agcaagattt gttgttcacc tttttcaaag cgtttcttta gctgatgaac
     7081 atccccattt ttatactggg ccaagtggct aactgtaagt aaatccgata ctgctagaag
     7141 catgtcttta gcggtaaaga gaaccaaaat cggttgctgg aaagcttgaa tttccactag
     7201 taaagcagct acctctctgg catagacttc taaggaggtt tctgttacca gagggaaatc
     7261 tttgaccata accacttctt gttcctgttt tccccgagat tcaatcttga caaatttggc
     7321 ttcaggatag cctaaaaggt ctgccaaaga aaccctctga ctaatctcaa gagtagccga
     7381 tactcccaag acttggcaac tctcaggaag taaagaggac agaagagtac ggcctgattt
     7441 tgtagaagaa atctgaattt tcttttgact cgtttcagtt acttcaagcc agtaatcacc
     7501 ttcagctgta aaatagcgaa ccagctcatc aaagccttcc acttctaatt ctgaaaaata
     7561 ctgatggaga ttgtccagag aatctaagat atttttccta gatttaccag actgaaattg
     7621 ttctatcaag tagagacact caaagcgaat actttctagt atccgttgtt gaaccctgtt
     7681 ttcttctcct actaaagcct tatcaattaa atcgataata gattgtatat cgtaggtctc
     7741 ttgaagcaga ttttctagag ctaacaaaat cttttggact tcatcaataa tcagtaaacg
     7801 gtcactgaca aattcaggat tatcttcaag tctggtcacg agataggcat gattagtcac
     7861 taaaagcttg caagtctctg ccctttcttg actacgtttc caaaaatctt ccgtcacaaa
     7921 taagctctgg gatgataaat tcccatcatg acgaaggtct gctagaaaat gttggtaacg
     7981 gtagagttgc ccgatttcat ccaaatctcc tgtctctgtc tcagtaagcc agaccaagac
     8041 ttgcatttta aagcgtctaa ataagcgatt ttcatcattt tcctgcaagg aatgataaaa
     8101 ggcatccaac ttcagataat tttgtggtcc ctttaagcta tgaatatctg tatggaacac
     8161 ttccttgaga cgtttacctt cttcttccat gatttgattt tgaagaatct ttgtcggaac
     8221 actaagaaca atttgtcgct ctttggattg agataaagcg ggtaagagat agccataggt
     8281 tttcccaatc cctgtcggcg cttgaatcag agagaaaggt tcatctttca atagcaagcc
     8341 aacctcttta gcaaaacttt cttgttcctc cctcacttca aggttcaaca gagaaatatt
     8401 tttagaaaag tcttgagata gttttcgtag ctccagagaa gctgccgttt tcttaaaata
     8461 cagaccttga acttggacca agtctggaga actcaggata gattggttgc gataagtttc
     8521 ctcaataacc aggtaagact catataggag agcgtcagcc atttccagca agcgttccaa
     8581 gagaccttta ggaagctggg tcatcttttc ccgtaaaaaa agaagtaatt ctgctgtagc
     8641 ttgggcatct gaaagggctg tgtgtgcgtg tttaagagga attcctaatt ctcgacacaa
     8701 aatcggcaag ctatattttt ccagttcagg gaaaaagacc tgggccaatt cgaccgtatc
     8761 aacacgaggg tttcttagct catagccttc aaaaaataaa ttttccgcca agagattagc
     8821 atcaaactga acattatggg ctacaaaaat cccatcctcc accaagtcaa agatttttct
     8881 ggcaacttgc gaaaaatcag gtgcttgcgc cagacgttgg tctgtcaatc ctgtcagttc
     8941 tttgatatga gcatccaagg gttcatgtgg attgacatcc gtcgtatagt gatcgacgat
     9001 ttctccatcc tcaatcacga caattcccac ttggataatt ttagccttac tacctgtgct
     9061 agttgcctct aaatccacca caacatagcg attaccaatc gttttcatta taaaaaatta
     9121 taccaaaaaa agggccattt ggcacctgca aacataggat aattttcaaa ctcaagaaca
     9181 ctacttttct tagaaatccc atcgaataga gcattctagc ctgctgattt ttttaaaata
     9241 gtgaagaaat acgaaaaatt gagagaagaa atgttttcat cttccttctc tcaacgaatc
     9301 atgtatttta tttaaccatg tcaggatcgt agtcataaaa tcctgtatca aggaaacggt
     9361 ttttagggtg aagtttacga acttcttcat ccagcaagaa ggcttggtca tggctaaagt
     9421 tgccctcttg aatcaagcta cgcgcttgga taaagagttt tgcaatctca acaaagttct
     9481 gaccaggagt gtagagccct tctagtttcc agcgagtaaa gccatgctcc accaattctg
     9541 ttaatttgat catcaaatca aggtcattgt tggcaaagat atgggtccca tgattatctt
     9601 caaaaatgga atagtggctc tctggatcac ttggctcagc caagaagagg tcacgtttat
     9661 gcgtcttttc atcatcgata tgtgtaaagt tatagtagtt ttgcaagagt ggacgtttag
     9721 aatgatggat gacgctagca ccgtaaacca aaacttcagc aggaatttcc aaaatctctg
     9781 gcattttgaa aagttcagct gatggaattt cacgcgccaa aacagcctca gatgcgccag
     9841 ccttttgtcc ccagaagtta atctgacgac tgctagttac catggttgaa gcatcgtaga
     9901 tggtcttaaa tgaataacca tcgcggttaa ctacgtaaaa gacgcctgca tccccaatcg
     9961 taatatagtc tgtcttgatt tcttccaaga agtctaagaa aggcttgata cggtccatca
    10021 tatcttggtg catgagagca ttgaccgcaa cgatcaattc cttaccagca tcatgaacca
    10081 acttagcgat ttcacgtaat tggtcataac taaaggtcgt tggcagacga aggccaaaat
    10141 ctttctcacc gacatagata cggtctacgc cagcttcgag tagttgttca acttgttcaa
    10201 tactttcagc agttgctgta atgacaatct tttccataag aaaaattata ccacatttct
    10261 ccaaaatcag ccatgctttg aaaatgaaaa gggactttat tctttttgta acctttctgt
    10321 aataattctc tgccgaaaaa atgataaaat aggtatgtac tgttaaggag agaatcatgc
    10381 ccgtaagaaa attacaatcc tatgaggtag actatcaaga agaattaaac cagcagcttc
    10441 ctcattacca agcttataca cctgaagcgc aatctgatgc caatctcaag gaaatcctat
    10501 tttttattaa tatcgctgtt ttttgtatct gtattgctat ctttagtttt atctttttag
    10561 cattaaaatt atcaactgct cttgcctttg ccgcagcaat cggattcagc ttacttgttt
    10621 taaaagttca acggtctatt atcaaacgaa aacgtagaag ataaatccaa aatatcgccc
    10681 caattggagc gatattttta ttttttcttt ttagatggtg tctgaatggc aatcttcact
    10741 tcaaagattg ttcccttggg tttattatct ttgacagtaa cagttccttt tagagcatct
    10801 acaatttgct tggctaggga taatcctaaa ccaaaaccac ctttttgccg ggttctagct
    10861 ttgtctactc gataaaaacg gtcaaaaatt ttctttttat cttctgtcga aataccgatt
    10921 ccattatcag aaacaagtaa ataaagattg cgatcggtcg ccgagataag aaaatcaatt
    10981 tcaccatcct cctcagtata cttgacggca ttatcgaaaa gaatggtcat cagttgtttc
    11041 agaagaagct gatctgtgac aattgttcga tggatacgat tttcaaaacg gaagacacga
    11101 ttattttccg aagcaatcat ctcatagttt gtgaaagttg tattaaaaaa gctagttgga
    11161 acttctgcaa gctccggctt aatcccatca tctctccgag ctaagttcag caagcttgtc
    11221 gttaaaaaac gcatatttcg gacttcttcc aaactcgatg caatgctttc gctcacatcc
    11281 ataatggtag cttctggctt acgaaaaagg gtctctaagc gattttgcaa aactgcgagt
    11341 ggagttcgta actcatgact ggcattttcc acaaaagact gttgcttctg catactctca
    11401 agcaggggcc taacactgac cctagctaga tagagactgg caagtaaaga caaaatccag
    11461 aaactagcca tcacgaccac aatcaattgc tcatgctttt gactagcctg ctccaactga
    11521 ctggtattaa tcaagacagc agcatacttg atattggttg aaaccgaact aatattggtc
    11581 tccatcaaaa tcacacgata gatttcttcc tgcccatagc tattaaaaac ctgaatctgg
    11641 tagatatgtc ctagttcttt cttttctaac ttaatcttat ccaagcccaa aaatcgattt
    11701 ccagaaagaa gttgagtaaa gtctttatca aagagaatga cttccgtatt ggaactgaca
    11761 ttaggtttta tttctacttt actagcgtcc gccctagcat tttctaaatc tttaatctct
    11821 tctgttgccc tatttatagc cagctgaata actgcttgag gattttcact cagtccatga
    11881 agcttatcgt ccaccgaagt ataaagactc gaatgcatga cttgtaaaat aatcagagtc
    11941 attgtagaaa aaatcagggt gaagacaccg aagttgcgga taaaataact aaagtcatcc
    12001 gcataccatg tttttttaag tttactgaac atcttttaaa agatacccaa cactacgcaa
    12061 ggtttgcaaa ttctctgcaa aagtggttcc ctttaatttc ttacggactt ttgaaacata
    12121 gacttcgaca accgaaatcg ttgtatcact atcaaatccc catagacggt caaaaatctg
    12181 cgtcttaggc aaaatcacat tttgattttg aaggaaataa actagtaaat cgaactcttt
    12241 ccccagcaat tcgacaggag tatcttcaac tttaacggta ttggttgata aattaaccac
    12301 gatattccca taagtcaagg tgttttcatt aaacttccct gaacgtttga gaagggcctg
    12361 aattcgcatt ttaagttctt ctaggtagaa aggtttggtc agataatcat ccgctcccag
    12421 ttcaaatcca tgtcccttgt catccaaact ttccttggca gtcataatca gaactggtgt
    12481 cgtaattccc ttttcacgca attcttttaa gacttggaaa ccattttttt ctggcaacat
    12541 caaatccagc aaaatcaagt catagacacc actctcagct tcgtagagac cttcttctcc
    12601 atcaaatacc tgcataacat ccgcaaaatc gtctaaaaag tcaaatactg aatttgacag
    12661 acctaggtca tcctcaacca ataagatttt tatcatgaga aactcctcct tattaaaact
    12721 attataccaa atttgcctta aaaaaaactc aactctctgc attttacatg agatagctga
    12781 gttttct
//
LOCUS       DBEJJV010000053        11920 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.053, whole genome shotgun sequence.
ACCESSION   DBEJJV010000053 DBEJJV010000000
VERSION     DBEJJV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11920
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.053"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..177
                     /locus_tag="ACL3GT_001873"
     CDS             <1..177
                     /locus_tag="ACL3GT_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HGR0517482.1"
                     /translation="VEDKACNHALSKERSKVENIFAKVKTFKIISTTYRNHRKRFGLR
                     MNLSAGIINHELGF"
     gene            368..2659
                     /gene="pcrA"
                     /locus_tag="ACL3GT_001874"
     CDS             368..2659
                     /gene="pcrA"
                     /locus_tag="ACL3GT_001874"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HGR0517483.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNNLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2702..3382
                     /gene="radC"
                     /locus_tag="ACL3GT_001875"
     CDS             2702..3382
                     /gene="radC"
                     /locus_tag="ACL3GT_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HGR0517484.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQVSV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3379..4068)
                     /locus_tag="ACL3GT_001876"
     CDS             complement(3379..4068)
                     /locus_tag="ACL3GT_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HGR0517485.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4086..4727)
                     /locus_tag="ACL3GT_001877"
     CDS             complement(4086..4727)
                     /locus_tag="ACL3GT_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HGR0517486.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4810..5025)
                     /locus_tag="ACL3GT_001878"
     CDS             complement(4810..5025)
                     /locus_tag="ACL3GT_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HGR0517487.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5033..5380)
                     /locus_tag="ACL3GT_001879"
     CDS             complement(5033..5380)
                     /locus_tag="ACL3GT_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HGR0517488.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5385..6500)
                     /locus_tag="ACL3GT_001880"
     CDS             complement(5385..6500)
                     /locus_tag="ACL3GT_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HGR0517489.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6510..7469)
                     /locus_tag="ACL3GT_001881"
     CDS             complement(6510..7469)
                     /locus_tag="ACL3GT_001881"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HGR0517490.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDHPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7582..8151)
                     /locus_tag="ACL3GT_001882"
     CDS             complement(7582..8151)
                     /locus_tag="ACL3GT_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HGR0517491.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8279..8950
                     /locus_tag="ACL3GT_001883"
     CDS             8279..8950
                     /locus_tag="ACL3GT_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HGR0517492.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGVKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8934..9752
                     /locus_tag="ACL3GT_001884"
     CDS             8934..9752
                     /locus_tag="ACL3GT_001884"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HGR0517493.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9749..10645
                     /locus_tag="ACL3GT_001885"
     CDS             9749..10645
                     /locus_tag="ACL3GT_001885"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0517494.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10689..11663
                     /gene="pta"
                     /locus_tag="ACL3GT_001886"
     CDS             10689..11663
                     /gene="pta"
                     /locus_tag="ACL3GT_001886"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HGR0517495.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
BASE COUNT         3477 a         2284 c         2571 g         3588 t
ORIGIN      
        1 gttgaagata aagcctgtaa ccatgcgcta tccaaggaga gaagcaaggt tgagaacatc
       61 tttgccaaag taaaaacgtt taaaataatt tcaacaacct atcgaaatca tcgtaaacgc
      121 ttcggattac gaatgaattt gagtgctggt attatcaatc atgaactagg attctagttt
      181 tgcaggaagt ctattgaggt attgagctag tttatgaaaa aattgggtga aaagtcgagt
      241 gttttagaaa cccacagtgt agtattctag tttcaatcca ctatattttg ctactccccg
      301 taaagtttct attttccctg atttctgata taatagaaat attgacttca agagtaagga
      361 agagaagatg aacgcattat taaatggaat gaatgaccgt caggctgagg cggtgcaaac
      421 gacagaaggt cccttgctaa tcatggcagg ggctggttct ggaaagactc gtgttttaac
      481 ccaccgtatc gcttatttga ttgatgaaaa gctggtcaat ccttggaata tcttggccat
      541 tacctttacc aacaaggctg cgcgtgagat gaaagagcgt gcttatagcc tcaatccagc
      601 tactcaggac tgtctgattg cgaccttcca ctccatgtgt gtgcgtattt tgcgtcgcga
      661 tgcggaccat attggctaca atcgtaattt tacaattgtg gatcctggtg aacagcgaac
      721 gctcatgaaa cgtattctca aacagttgaa cttggatcct aaaaaatgga atgaacgaac
      781 tattttgggg accatttcca atgctaagaa taatttgatt gatgatgttg cttatgctgc
      841 ccaagctggc gatatgtata cgcaaattgt ggcccagtgt tatacagcct atcaaaaaga
      901 acttcgtcag tctgaatccg ttgactttga tgatttgatt atgctgacct tgcgtctctt
      961 tgatcaaaat cctgatgttt tgacctacta ccagcaaaaa ttccaataca tccacgttga
     1021 tgagtaccaa gataccaacc acgctcagta ccaattggtc aaactcttgg cttcccgttt
     1081 taaaaatatc tgtgtggttg gggatgcgga ccagtctatc tacggttggc gtggtgctga
     1141 tatgcagaat atcttggact ttgaaaagga ttaccccaaa gccaaggttg tcttgctgga
     1201 ggaaaattac cgctcaacca aaaccattct ccaagcggcc aacgaggtta ttaaaaataa
     1261 taaaaatcgc cgtcctaaaa atctctggac tcaaaacgct gatggggagc aaatcgttta
     1321 ctatcgtgcc gatgatgagc tggatgaggc tgtatttgta gccagaacca tcgatgaact
     1381 tagtcgcagt caaaacttcc ttcataagga ttttgcagtt ctctatcgga ctaatgccca
     1441 gtcccgtaca attgaggaag ccctgctcaa gtctaacatt ccttatacca tggttggcgg
     1501 aaccaaattc tacagccgta aggaaattcg cgatattatt gcttatctca accttattgc
     1561 taatttgagt gacaatatta gttttgagcg tattatcaac gagcctaaac gtggaattgg
     1621 tctaggtaca gttgagaaaa tccgtgattt tgcaaatttg caaaatatgt ctatgctgga
     1681 tgcttctgct aatattatgt tgtctggtat caagggtaag gcagcccaat ctatctggga
     1741 ttttgccaat atgatgcttg atttgcggga gcagctagac cacttaagca ttacagagtt
     1801 ggttgagtcc gtcctagaaa aaacaggtta tgtcgatatt cttaacgccc aagcgactct
     1861 agaaagcaag gcacgggttg aaaatatcga agagtttctt tctgttacga agaactttga
     1921 tgacaccacg gatgtgacag aagaggaaac tggtctggac aaactgagtc gtttcttaaa
     1981 tgacttggct ttgattgccg acacagattc aggtagtcag gagacatcag aagtgacctt
     2041 gatgaccctg catgctgcca aaggtctcga atttccagtt gtctttttga ttgggatgga
     2101 agaaaatgtc tttccactta gtcgtgcgac tgaagatcca gatgaattag aagaagagcg
     2161 ccgtctagcc tatgtaggta tcacgcgtgc agagaaaatt ctctatctga ccaatgccaa
     2221 ctcacgcttg ctttttggtc gtaccaatta taaccgtccg actcgtttta ttaacgaaat
     2281 cagttcagac ttgcttgagt atcaaggtct ggctcgtcct gcaaatacaa gctttaaggc
     2341 atcatatagc agtggtagta tttcctttgg tcaaggtatg agtttggctc aggctcttca
     2401 agaccgtaaa cgcggtgctg ccccaaaatc aatccagtca agcggtcttc catttggtca
     2461 atttacagct ggcgcaaaac cagcatctag cgaggcaaat tggtccattg gtgatattgc
     2521 tctccacaag aaatggggag agggaaccgt tctggaagtt tcaggtagcg gtgctaggca
     2581 ggaattgaaa atcaatttcc cagaagtagg tttgaaaaaa cttttagcca gtgtggctcc
     2641 aattgagaaa aaaatctaat tttccatcct tctcacgaat aataaagtga ggaggatttt
     2701 tatgtacagt atttcattcc aagaagattc actattacca agagaaaggc tggccaagga
     2761 aggagttgaa gcgcttagta accaagagtt gctagctatt ttactcagga caggaacacg
     2821 tcaagttagc gtttttgaaa ttgcccaaaa agtcttgaac aatctttcaa gcctaacgga
     2881 tttgaaaaaa atgaccctgc aggaattgca gagtttgtct ggtattgggc gtgttaaggc
     2941 catagaatta caagctatga ttgaactggg gcatcgtatt cacaaacacg agactcttga
     3001 aatggaaagt attctcagca gtcaaaagtt ggccaagaag atgcagcagg aattagggga
     3061 taaaaaacaa gagcacctgg tggcactcta tctcaatact caaaatcaaa tcatccatca
     3121 gcagaccatt tttatcgggt ctgtaactcg tagtatcgct gaaccgcgag agattcttca
     3181 ctatgcaatc aagcatatgg cgacttctct tatcttggtc cacaatcatc cttcaggagc
     3241 ggtagcgcct agccaaaatg atgatcatgt cactaaactt gttaaagaag cctgcgaatt
     3301 gatggggatt gttctcttgg accatttgat tgtctctcat tctaattact ttagttatcg
     3361 tgaaaagaca gatttaatct aaagttcatt aacgacatag tcaaagagtt ttttatcttt
     3421 gggacgattt tcaaaaagaa gttctggatg ccattggaca ccgagaaagg cgacatcatc
     3481 cgtactcatg acagcctcaa tgataccatc tttaggatca tgagccacaa cttttaaatt
     3541 tggtgctaag tccttgatgc tctggtggtg gaaggagttg atatgagaga tttctccata
     3601 gatttcttgg agaacggtat ctggttctgt taccaagcgt tgagttgtgt actcaacaga
     3661 agaatcctgc caatggtctt cgatatcttg gtacaaagtt ccacccatgg caacgttaaa
     3721 gagttgggta ccacggcaga cagagaaaat gggctttttc tgtttaatag cttccttgat
     3781 gagggtcagt tcgaagatat ctctttgaag gtgatagtca tcgctatcaa tggttttggg
     3841 ttcgccataa aattttggat cgacattttg cccacctgtc aagatgagct tgtcaatcaa
     3901 actgatatag tggcaggcca tttcttgatc accaatcggt aggatgatgg gaatccctcc
     3961 agcatcttta acgccttcaa caaagccttt tgctgcgtag ctcatcatga tgtcatcatc
     4021 tggatgagct ttttcgtttc ctgtaatccc aataactggt tttttcataa aatgattttc
     4081 gctttctaat cctcttttcg catgaagtag aggagggttt ggagttcact tgtcaaatcg
     4141 acatactgaa cgaccacgtc ttttggtaaa tgcagatgga ctggtgaaaa actgagaatt
     4201 cctttcacac cagcatcaac caagagatta gcaacctctt gtgacttgac gctgggaaca
     4261 gttaggatag cagtcttcac atcagcatcc ttgattttat ccttgatctg agaaatcccg
     4321 taaatgggaa tcccgtcagg agtttgggta ccgacttcag gatggtcgtc taggtcaaag
     4381 gccatgataa tcttcatctt gttacgttcg tggaagcggt agtggagaag ggcatggccc
     4441 atatttccaa taccaaccag catgacattg gtaatagagt tgtcattgag caaatcggca
     4501 aaaaatgtca ttagtttttt gacatcatag ccaaaaccac gacgaccaag ttcaccaaaa
     4561 taggaaaaat cacgacgtac ggtcgctgaa tcaataccga tagcctctgc aatttgctta
     4621 gagttggcac gttcaatctt ttctgcatga aatctcttaa aaattcgata gtagagagag
     4681 agtctttttg ctgtagcttt tggaatagca aactgtttat ctttcacaaa atcacaacct
     4741 ttctattctt ctattttata gaaacattgt gaaaaaatca acaaaaataa gaaaaaacta
     4801 agaaaaatct tagttttgat gtaaaaaatc tgcatgagat agaaaacggt agaggtctcc
     4861 gaccagaccc tgataaactt tttggcccct aaaagtcaga gaagtcacat aaagtgtatc
     4921 tggtaaggtt acacatcctg acaaagtcaa catgagagcc tcatgatcct catacttgag
     4981 agtacgctct acatgatagc agtccttata ggtcagttca aacattttgg ctctatcttt
     5041 ccgattttgt aaagacacca cgttctacca agctatccat gaggaagtag aatttttcct
     5101 gatgaatatg gtggtcttct gatttgaaaa tatcaactag acgaaggcca aacttgtcag
     5161 tgatattgat tttagcccct gtaagttcct tgttaatgat gattttgagt tggaagcctt
     5221 caccgctgtt tggcactttt tccaaaaggc gagtcagttc atagttacca accttagttt
     5281 caaaaaaggt gttatctttg agggtgaatt ttttaacaga agggctaaga gtgtaatcgt
     5341 aacgacaatt ttttaactga atgatttttt caaatgccat atggctaacc tccgataatt
     5401 tcttttaagg tttttgcgag ggtttgtagg tcttcaacgg tattttgtgg cgacaaactg
     5461 atgcgaaggg attccttcaa gcgttctgaa tttgcgccat acatggcttc aagaacatgg
     5521 ctggattgga caacgcctgc agtacaggct gagccagtag agattgaaat tccagctaaa
     5581 tctagccgaa ggagtaagag gtcatttttc tgaccaggaa atccaatatt gagaacataa
     5641 gggagatgat gttttcctct attcaagtaa tactgaatgc cctccagctc tgccagaaag
     5701 gcagtttcta gattttgtac atgttgaaaa tgttcttctt gtttttctag gtcttctttt
     5761 agggctgcaa ccatgcctac gatagcaggc agattttcag ttcctgcacg ttttttctgt
     5821 tcctggtctc cgccatgtag ataggaatca aagtccatgc tagatgcgta gagaaaaccg
     5881 attcccttag gaccatggaa tttgtgggca gaagcagtga gaaaatcaat gcccaattct
     5941 tctgaatgaa ttgggatttt accaatagcc tgaactgcat caacatgata ggcagcaggg
     6001 tgttgcttga gtatttggcc aatttcagcg atgggcagta ggtttcctgt ctcattattg
     6061 gcaaacatgg tagaaaccaa aatcgtatcg tcacgtaaag ccttttgaat ttgctgggct
     6121 gtgatttctt gattttctgg ctggataatg gttgcttcaa acccaaagtg ttgaaccaag
     6181 taatcaattg tttcaaggac agcatggtgc tcgatggcag ttgtgatgat atgttttcct
     6241 tgttcttggt gacgaagaca gtagccaatg atggtagtat tattgccttc agtcccacca
     6301 gaagtgaaaa agatatgttg aggttttgtc cttagtaact gggctagttc ctgacgggct
     6361 tctcgcaaga gtttgccagc ttgacgacca tgaccatgaa tactagaagg atttccgtgg
     6421 gtttcttgca taaccttggt catagctgaa atagcaactg ctgacatagg agtcgttgca
     6481 gcattgtcca aataaatcaa agaatcacct tatttctttt tattgtaggc aaagagtggg
     6541 ctgactggtt ttctttcgtg aatacggacg atagcatcac caattaactc actagcagtg
     6601 atgtagcata catttttagg agttttttct tttgttgcta ctgaatcagt cacaagaatt
     6661 tctttaatat tagtattgtc aagaagctca gcagctccct cgacgaagag accgtggcta
     6721 gaaacagcat aaatttctgt agctccttca cgttcaacga ttttagaagc ttcagagaag
     6781 gtacgtcctg tatttaaaat atcatcaatc aagatagctt tcttaccttc aacatcacca
     6841 ataatataac cttcgttacg agttgcatcg tcttgagggt ggtcgataat ggcgatagga
     6901 gcatcaagat attcagccag gctacgcgca cgtttgacac ctgaattttt agggctaacg
     6961 acaacaacat ctgaaccaag caatccttta tcgcagtaat gttttgcgaa taggggaaca
     7021 gtgaaaagat tatccactgg aatatcaaag aaaccttgaa cctgaacggc atgcaaatca
     7081 agagtcagga tacgatcaac tccagcctta accagcatat tggcaactag ttttgctgta
     7141 agtggctcac gaggacaagc aatgcggtct tgacgtgcat agccaaaata tggaaggaca
     7201 acgttgatac tgtgggcact tgcacgcaca caagcatcga ccatgattaa caattccatt
     7261 aggtggttgt tgacagggaa acttgttgat tggatgatgt aaacatcata accacggaca
     7321 ctttcttcga tatttacttg gatttctccg tctgaaaatt gacgtgatga tagttttcca
     7381 agtgggacac caacagcttg ggcaattttt tgtgcaatct cttggttaga gttgagtgcg
     7441 aaaagtttca tgttttttct atctgacatt atagaccgtc ctctgtaaac tttataaatc
     7501 ctagttatat ttaccttaca tatatgaact gggatttgtg tatttttatc ttttctattt
     7561 taccaaaaaa tggagattat ttcagctatt tttcatactt ttgacaaatc gaaccaattt
     7621 tgaaggagct ttttggtagg aaatctgatt tttctctaaa aattgtcgga aatcctgttt
     7681 gccttgctca tgattttcca cttcaagctc caattcgtaa tctgttatat caaagtatcg
     7741 gctctgatcc agtgccatga gaccaatagc tgttttcatt tcatagcgaa gcgttgttag
     7801 acaaccaaga acctgccagt tcttactttg gataccatgt ttcgccaatt catccagtac
     7861 tagcccttga ggaagttctt ccttactcag atagttctca gcatctttta gttgcaattt
     7921 ttggttgtat tccatgtttc caacactctg cgggactttg agtgtcaact cagcccagtc
     7981 ttcaaaggtt cgaatgcgca tagcgacttt cttttctcgc agttcaaaat caggcgtgtc
     8041 gatgtagtaa tttgtttgaa gaacaggagt gacacctgtg aactggtctt ttagacgatt
     8101 gtattcatct tttttcaata gtgttttcaa ttcaatttct aaatgtttca tttttcttac
     8161 ctttttttat cgttgaaagc ggatttatgg tataataagc attgtattta ttgtatatga
     8221 atctggagaa aaaatcaaag atatttttga cggataatat gagaacaagg gagaatatat
     8281 gaccttagaa tgggaagaat ttctagatcc ttacattcaa gctgttggtg agttaaagat
     8341 taaacttcgt ggtattcgta agcaatatcg taagcaaaat aagcattctc caattgagtt
     8401 tgtgaccggt cgagttaagc caattgagag catcaaagaa aaaatggctc gtcgtggcat
     8461 tacttatgcg accttggaac acgatttgca ggatattgct ggcttacgtg tgatggttca
     8521 gtttgtagat gacgtcaagg aagtagtgga tattttgcac aagcgtcagg atatgcgaat
     8581 catacaggag cgagattaca ttactcatag aaaagcatca ggctatcgtt cctatcatgt
     8641 ggtagtagaa tatacggttg ataccatcaa tggagttaag actattttgg cagaaattca
     8701 aattcgtact ttggccatga atttctgggc aacgatagaa cattctctca actacaagta
     8761 ccaaggggat ttcccagatg agattaagaa gcgactggaa attacagcta gaatcgccca
     8821 tcagttggat gaagaaatgg gtgaaattcg tgatgatatc caagaagctc aggcactttt
     8881 tgatcctttg agtagaaaat taaatgacgg tgtaggaaac agtgacgata cagatgaaga
     8941 atacaggtaa acgaattgat ctgatagcca atagaaaacc gcagagtcaa agggttttgt
     9001 atgaattgcg agatcgtttg aagagaaatc agtttatact caatgatacc aatccggata
     9061 ttgtcatttc cattggcggg gatggtatgc tcttgtcggc ctttcataag tacgaaaatc
     9121 agcttgagaa ggtccgcttt atcggtcttc acactggaca tttgggcttc tatacagatt
     9181 atcgtgattt tgagttggac aagctagtga ctaatttgca gctagatact ggggcaaggg
     9241 tttcttaccc tgttctgaat gtgaaggtct ttcttgaaaa tggtgaagtt aagattttca
     9301 gagcactcaa cgaagccagc atccgcaggt ctgatcgaac catggtggca gatattgtaa
     9361 taaatggtgt tccctttgaa cgttttcgtg gagacgggct aacagtttcg acaccgactg
     9421 gtagtactgc ctataacaag tctcttggcg gtgctgtttt acaccctacc attgaagctt
     9481 tgcaattaac ggaaattgcc agccttaata atcgtgtcta tcgaacactg ggctcttcca
     9541 ttattgtgcc taagaaggat aagattgaac ttattccaac aagaaacgat tatcatacta
     9601 tttcggttga caatagcgtt tattctttcc gtaatattga gcgtattgag tatcaaatcg
     9661 cccatcataa gattcacttt gtcgcgactc ctagccatac cagtttctgg aaccgtgtta
     9721 aggatgcctt tatcggtgag gtggatgaat gaggtttgaa tttatcgcag atgaacatgt
     9781 caaggttaag accttcttaa aaaagcacga ggtttctaag ggattgctgg ccaagattaa
     9841 gtttcgaggt ggagctattc tggtcaataa tcaaccgcaa aatgcaacgt atctattgga
     9901 cgttggagac tacgttacca ttgacattcc cgctgagaaa ggctttgaaa ccttggaggc
     9961 tattgagctt ccattagata ttctctatga ggatgaccac tttctagtct tgaataaacc
    10021 ctatggagtg gcttctattc ctagtgttaa tcactctaat accattgcca attttatcaa
    10081 gggttactat gtcaagcaaa attatgaaaa tcagcaggtt cacattgtta ccagactaga
    10141 tagggacact tctggcttga tgctctttgc caagcacggt tatgcccatg cacgattaga
    10201 caagcagttg cagaagaaat ctatcgagaa acgctacttt gctttggtta agggagatgg
    10261 acatttggaa ccagaagggg aaattattgc tccgattgcg cgtgatgaag attccattat
    10321 taccagacga gtggctaaag gcggaaagta tgcccatact tcatacaaga ttgtagcttc
    10381 ttatggaaat attcacttgg tctatattca cctgcacact ggtcgaaccc atcaaatccg
    10441 agtccatttt tctcatatcg gttttccttt gctgggagat gatttgtatg gtggtagtct
    10501 ggaagatggt attcaacgtc aggctctgca ttgccattac ctatcctttt atcatccatt
    10561 tttagagcaa gacttgcagt tagaaagtcc cttgccggat gatttcagta accttattac
    10621 ccagttatca actaatactc tataaaaact gtctcagagt ataattatta tcttaaagga
    10681 gaaaactcat ggaagttttt gaaagtctca aagccaacct tgttggtaaa aatgctcgta
    10741 tcgttctccc tgaaggggaa gagcctcgta ttcttcaagc aacaaaacgc ttagtaaaag
    10801 aaacagaagt gattcctgtt ttgcttggaa atcctgaaaa aattaaaatt tatcttgaaa
    10861 ttgaaggaat catggatggt tatgaggtca tcgaccctca acattatcct caatttgaag
    10921 aaatggtttc tgccttggtg gagcgtcgca agggcaaaat gactgaagaa gatgtacgca
    10981 aggttttggt tgaagatgtc aactactttg gtgtgatgtt ggtttacttg ggcttggttg
    11041 atggaatggt gtcaggagcg attcactcaa cagcttcaac agttcgccca gctctacaaa
    11101 tcatcaaaac tcgtccaaat gtaactcgta cttcaggagc cttcctcatg gttcgtggta
    11161 cggaacgtta cctatttgga gactgtgcca ttaatatcaa tccagatgca gaagccttgg
    11221 ctgaaattgc catcaactca gcaatcacag ctaagatgtt tggcatcgaa cctaaaattg
    11281 ccatgttgag ctattctact aaaggttcag ggtttggtga aagcgttgat aaggtcgttg
    11341 aagcaactaa aattgctcac gacttgcgtc ctgaccttga aatcgatggt gagttgcaat
    11401 ttgatgcggc ctttgttccc gaaactgcag ctctgaaagc tccgggaagt acagtagctg
    11461 gtcaagcaaa tgtcttcatc ttcccaggta tcgaggcagg aaatatcggt tacaagatgg
    11521 ctgaacgcct gggtggcttt gcggctgtag gacctgtttt gcaaggttta aacaagccag
    11581 ttaatgatct ttctcgtgga tgtaatgcag atgatgttta caagttgacc ctcatcacag
    11641 cagctcaagc agttcatcaa tagtgaaaac tataaagtga tatactatgc tatactgtag
    11701 ttatgaaact atgtacgaaa agcactgcca ttaattcctg agaactaaat tactgattgg
    11761 tgtcaaaaag gaaaacttcc aagcgatgat atcctgtcta tacacgacct atagaaatct
    11821 gtaatataca tatccgtaaa acgataaatt ccctttttga ttttaaatga gtatgaaaag
    11881 agaatttttt ggctctttgt caactgtagt gggttgaagt
//
LOCUS       DBEJJV010000054        11877 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.054, whole genome shotgun sequence.
ACCESSION   DBEJJV010000054 DBEJJV010000000
VERSION     DBEJJV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11877
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.054"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            436..1146
                     /gene="deoD"
                     /locus_tag="ACL3GT_001887"
     CDS             436..1146
                     /gene="deoD"
                     /locus_tag="ACL3GT_001887"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HGR0517496.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1169..1693)
                     /locus_tag="ACL3GT_001888"
     CDS             complement(1169..1693)
                     /locus_tag="ACL3GT_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HGR0517497.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1746..1982)
                     /gene="rpsT"
                     /locus_tag="ACL3GT_001889"
     CDS             complement(1746..1982)
                     /gene="rpsT"
                     /locus_tag="ACL3GT_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HGR0517498.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(2050..2970)
                     /gene="coaA"
                     /locus_tag="ACL3GT_001890"
     CDS             complement(2050..2970)
                     /gene="coaA"
                     /locus_tag="ACL3GT_001890"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HGR0517499.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3161..3564
                     /locus_tag="ACL3GT_001891"
                     /pseudo
     CDS             3161..3564
                     /locus_tag="ACL3GT_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3771..4361
                     /locus_tag="ACL3GT_001892"
     CDS             3771..4361
                     /locus_tag="ACL3GT_001892"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HGR0517500.1"
                     /translation="MSKMYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDF
                     GSQLLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEK
                     NNAKATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQ
                     KKQGAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4358..5635
                     /locus_tag="ACL3GT_001893"
     CDS             4358..5635
                     /locus_tag="ACL3GT_001893"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HGR0517501.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5653..6315
                     /gene="deoC"
                     /locus_tag="ACL3GT_001894"
     CDS             5653..6315
                     /gene="deoC"
                     /locus_tag="ACL3GT_001894"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HGR0517502.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6302..6691
                     /locus_tag="ACL3GT_001895"
     CDS             6302..6691
                     /locus_tag="ACL3GT_001895"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HGR0517503.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6782..7834
                     /locus_tag="ACL3GT_001896"
     CDS             6782..7834
                     /locus_tag="ACL3GT_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HGR0517504.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQDWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7978..9513
                     /locus_tag="ACL3GT_001897"
     CDS             7978..9513
                     /locus_tag="ACL3GT_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0517505.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGAINADLAEMMVGRSVSFKTKKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            9506..10564
                     /locus_tag="ACL3GT_001898"
     CDS             9506..10564
                     /locus_tag="ACL3GT_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0517506.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10567..11523
                     /locus_tag="ACL3GT_001899"
     CDS             10567..11523
                     /locus_tag="ACL3GT_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0517507.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            11608..11817
                     /locus_tag="ACL3GT_001900"
                     /pseudo
     CDS             11608..11817
                     /locus_tag="ACL3GT_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3414 a         2112 c         2705 g         3646 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaccccacc
      181 ctaaaagcag tgggaaaaag atagttggtc tagcgagcat cgctcactgc gcccaactcc
      241 tattttccct tcgctttttg acgggtttgg tatctttctc aatataaaat ataaaataaa
      301 gaaaggtaga gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc
      361 tgactgaaaa atcaggattt ctcgtcggct tcctaatttt cagtcgtttt cttctcgctc
      421 tttgtatcat aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa
      481 attcttcttc ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttgatgat
      541 gctgtttgtt ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac
      601 cgtgtatctg tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag
      661 ttaatcgtag actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat
      721 gaagaggttc atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc
      781 gttcgtaatg actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat
      841 aaagcctacc atatcgccaa agaacttggt atgactactc acgttgggaa cgttttgtca
      901 tctgatgtct tttactcaaa ttactttgaa aagaatatcg agcttggtaa atggggagtc
      961 aaggctgtgg aaatggaagc agcagctctt tactatcttg ctgcccaata ccatgttgat
     1021 gcgctagcta tcatgaccat ctctgatagc ttggtcaatc cagacgaaga cacaactgca
     1081 gaagaacgtc aaaatacctt cactgatatg atgaaggttg gtttggaaac cttgattgca
     1141 gaataattat agccaaaaag gaagcccttt atgaattgta ggacttcctt ttcttatcca
     1201 gaaattgatc tagctctctc tgatttcgaa gaatagtgac tttatgtgaa tattcttggc
     1261 aaagtttttg gtaattttct ttttgagttt tgctacgccc atcccaaaga atccatctga
     1321 taaactccca ctcaaagcgt tcagggcaat ctgccgccat actttctctg acttttccac
     1381 ggtatttaag ataacgctta aaggctctaa agagacaggt caatggcaaa aaattgagaa
     1441 agatgatttg gtcagcttct tgcattcgtt cttggtagta gcaccaagaa taattaccat
     1501 cgatgaccca agctttatgc ttggtgagaa agttttttat ctcggttaac atccattcgc
     1561 agtcactgtc ttgccaacca ggttgaaatt ggagtgtgtc catgtgcagt tttggaatgg
     1621 agtagtagtt agataacttt tctgctagag ttgacttacc agaaccagaa tatccgataa
     1681 ttgtgatttt cattttctac cttttcctat ttggagacaa aaaaacagcc tctatggact
     1741 gtttcttatt tagcaagttt agttgaaaga cgagctttat cgcggcttgc tttgtttttg
     1801 tgaatcaaac ctttagtttc tgctttatcg atagctgagc tagcagcacg gaaaagttct
     1861 tcagatgggt ttgcttcgaa agcttttata gcagtacgca tagctgattt ttgagctgag
     1921 ttcttttcgt tttgtttaac gttcaattca gcgcgtttga tagctgattt aatgtttgcc
     1981 aatgttctta cctccatatt tactaactat accattatat atgaaaactt acgttttgac
     2041 aagggaaaat tactttttta agtaaatttc atcgatttca tggttcttgc ttttatgaag
     2101 aatcacttct gcacgatttc tggttggttc aatataattt tgcagatttg tgagattgat
     2161 actgatccag acctgatggg caaaggactc cacttcccca atcggcatct gagtaaaacg
     2221 ataatagtag ctatcagggt cgttttgggc taggctcagc atcttcaaga aacggtccag
     2281 ataccaactt tcaatatcat ctactccagc atctacatag atggaaaagt caaagaagtc
     2341 agtgatatag agacgatcgt tttgtggatt ttgaaagaca ttaattccct caacaattac
     2401 aaaatcagca gctttgacac tttgtttctt ttcgggtacg atgtcgtaaa cttcatgaga
     2461 atagacagga atatctacat cttgtccatt tttgatgcgg tccaagaagt tgagaagagc
     2521 ttccatatca tagctttcag gaaatccttt acgatttaaa atcccctgct caatcaaggt
     2581 ttgattggga tagagaaaac catcagttgt aaccaactca accgtagcat ctgtaaacgt
     2641 acgggacagt aggatttgaa gtaggcgact ggttgtggat tttccaacgg caacactccc
     2701 agaaacccca ataataaaag gttgagattt actttcacgt tggaggaaaa ttccttttga
     2761 aaaggctaaa tcttccttag ttcgcttgta aatctgaatc agatgagcca aggggagata
     2821 gatatctgta acgtcttgga gactgatttg gtcattaaaa ctcttgatag attccaattc
     2881 ttcttctgtc aaaggaggtg ttgtctttcg atgtaaagat tgccaagtct ggcggctgat
     2941 tttttcaaaa tgtaaaaatt cgttggtcat ttgttttccc ctagatattt tgtctatcat
     3001 accataaaaa gctaaaaaaa taaagcggtt tcttgaatgt ggtaagtcaa tggtatatag
     3061 tataagtgat caatttattg atgaaatagg agatagattc tactgattta taagcttata
     3121 aagggggctt tttagttcac aacttagtag gaggtgtact atgaaaatct taaaacgtta
     3181 tatattggaa ctctgtttta ttttaagttt tgctttacct tttataaaag gaaccaatgc
     3241 agataatggt agatgctttg tggaaaccta ttacggtttt acttttttga tggaacatgc
     3301 tattgtaaca gctgtcttta tctgttcgtt cttaattgct ttcttactaa aaaacgatgg
     3361 acgaaatgga ttgctgcggg tagttattgc tttttagtcc tacggattgc gacagagggt
     3421 tatttcttcc acatgtcact agaagatttg atacgacttt ggacaagttt ggaaatcctg
     3481 acacaaacgt atcagttggg cttttatcta aacattttgt taggaatttt gttgataata
     3541 aagtatttta aggttaagca atagaaataa taatctgcct gattatagat gataaacttt
     3601 ttgtttttat ctggactgtg atatttatag ttctaaatgg tttattattt ataagtgttg
     3661 aaagagattg aagaaaatgg cttcgtgact tgctttcttc ggtctttttc gttttattat
     3721 caatttgtaa acgatttaca atttgagtca aattatggta aaatagtgtc atgagtaaaa
     3781 tgtactatgc agaaaatcct gacgctgctc acgacattca tgagttgaga gtggacttgt
     3841 tgggagaaaa aatgactttt ttgacagatg cgggtgtttt tagcaagaaa atggttgact
     3901 ttggaagtca actcttgctc aagtgtctgg atgtcaacca aggagagaca gtcctagatg
     3961 taggctgtgg ttatggtcca ttaggtttgt ccttggtcaa ggtttacgga gttcaggcga
     4021 ccatggttga tattaacact cgtgccctgg atttagctca gagaaatgct gaaaaaaata
     4081 atgcaaaagc gacgatattt caatctaata tttatgcaag agttcaaggg cgatttgacc
     4141 atgtcatttc caatcctcct atccgtgcgg gcaagcaagt cgttcatgaa atcatcgaga
     4201 aaagtaaaga tttcttggaa attggtggag atttgaccat cgtcatccag aaaaaacaag
     4261 gagctccaag tgccaaatct aagatggaag atgtgtttgg caattgtgaa atccttaaaa
     4321 aagacaaggg atactatatc cttagaagtg tgaaagaatg agagcagttg atttaatcca
     4381 aaaaaaacga gacggtcaag aactgacttc aagtgaaatt gaatggctga tagaaggcta
     4441 tgtatcagga actgttcctg attatcagat gtctgccttt gctatggctg tttattttaa
     4501 aggaatgacg actcgagaaa tctctgattt aacgatgaat atggttaaga ctgggcaaga
     4561 gtttgacctg tcagccattg atggtgtgaa agttgacaag cattctactg gtggtgtcgg
     4621 cgataaggta accttgattt tagctcctct tgttgctagc ttcggtgtgc ctgtagcaaa
     4681 aatgagtggt cgtggtcttg gccatacagg cggaacaatt gataaattgg agtccattag
     4741 gggctatcaa gtagaacgta gtcaagagga ttttattcgt caggttcagg atattggagt
     4801 atctgtcatt gggcaatcag accagctggt caaagcagat aagcttctct atgcccttcg
     4861 tgatgtgacc gcaactgtcg acacgattcc tttgattgcg agttcggtga tgagcaagaa
     4921 aattgcggca ggggcggatg ctattttgct agacgtgact gtcggtgagg gtgccttcat
     4981 gaagacggtt gatgaggcgc gtgagttggc tcaaactatg gtagatcttg gtaaggttgt
     5041 tggacggaag acagtagcag tgattacgga tatgagccag cctttggggc gagcgattgg
     5101 aaatcgtctg gaaatccttg aagcattgga gattttgcaa ggtcaaggac gtcaggatat
     5161 tacccacttt atttgtgaat tggctcaaat tatgcttggt ttggcaaatg ttaacaaaac
     5221 tgttgaagaa gttcgccaac atcttgaaaa tggtcaagca ctggctaagt ttgaggaaat
     5281 ggtgcaagcc caaggtggag acttggaaga cctctatcgt cctgtaaatg tagctcatgt
     5341 ggtggaaatc cctgctcagg aaacgggtgt catttcagct cttccagcta tggactttgg
     5401 tctttatgcc atgaggctgg gtgctggtcg tgcagttaag tctgatgtct tggactatga
     5461 aacaggaatt gtttttgaaa agaagattgg agactccgtt caaaagggtg aaattgttgc
     5521 aaaagtatac acaaatgaaa aaattccacc tcaactagtt acagatttcc aaaaatgtgt
     5581 taaaataagt gatgaagtga aaaaaatccg tgaaattgta gaaatcatct cctaaatgga
     5641 gggaaaaccg aaatgaaatt aaataaatat atagatcata cgcttttaaa acaagatgca
     5701 aagaaaaaac aaattgatag tttgttgtct gaggctagag agtatggctt tgccagtgtt
     5761 tgcgttaatc cgacctgggt tgaacatgct aaaaaaggac ttgaaggcac agatgttaag
     5821 gtttgcacag tagtaggttt ccccttggga gcaacaactt caactgtgaa agcttttgaa
     5881 acaaaagaag ctatccaaaa tggggctgat gagattgaca tggtaatcaa tgttggggct
     5941 ctcaagtcag gtgatttggc cttggttgag tcggatattc gtgcagtagt ggaagcaagt
     6001 ggggacaagt tagtgaaagt tattattgaa gcttgccttc tgacagacca agaaaaagtt
     6061 ttggcttgcc aattagccca aaaagcagga gctgactttg tcaaaacatc tactggcttt
     6121 tcaactggtg gtgctacgat agcagatgtt agattaatgc gtgaaacagt tggacctgat
     6181 atgggtgtca aggccgccgg tggagctcgt tcttatgcag atgctcttac ctttgtcgaa
     6241 gcaggtgcga cccgtatcgg aacgtcagct ggggtagcta ttttaaaagg agaattggca
     6301 gatggcgact actgagttga ttgaactggc aattgaaacc agcaaacatg cctatgtccc
     6361 ctattctcac tttcctatcg gagcagtttt agtagccaaa gacggaagtg tttacacggg
     6421 agtgaatatc gaaaatgcta gctatccttt gaccaattgc ggtgagagaa cagctatttt
     6481 taaggctata tctgaaggcc aaagagaatt ttcagaattg attgtctatg gtcaaactga
     6541 aaaaccgatt tcaccatgtg gtgcttgtcg ccaagtaatg gtcgaatttt ttgaacaaga
     6601 tttaaaagtg accctagtcg caaaagataa atcgacggtc gagatgacgg tcggggagtt
     6661 acttccatac tcttttacag acttaaatta gtctgagtcg ctctttgagt ggcaagggtc
     6721 tttgtgacca atcaatccat acttgcaaca tcgttgcaca tcttatttag gaggttcagt
     6781 aatgaacaag aaacaatggc taggtcttgg cctagttgca gtggcagcag ttggacttgc
     6841 tgcatgtggt aaccgctctt ctcgtaacgc agcttcatct tctgatgtga agacaaaagc
     6901 agcaatcgtc actgatactg gtggtgttga tgacaaatca ttcaaccaat cagcttggga
     6961 aggtttgcaa gactggggta aagaacacaa tctttcaaaa gataacggtt tcacttactt
     7021 ccaatcaaca agtgaagctg actacgctaa caacttgcaa caagcggctg gaagttacaa
     7081 cctaatcttt ggtgttggtt ttgcccttca caatgcagtt gaagaagcag ctaaagaaca
     7141 cactgacttg aactatgtct tgattgatga tgtgattaaa gaccaaaaaa atgttgcgag
     7201 cgtaactttc gctgataatg agtcaggtta ccttgcaggt gtggctgcag caaaaacaac
     7261 taagacaaaa caagttggtt ttgtaggtgg tatcgaatct gaagttatct ctcgttttga
     7321 ggcaggattc aaggctggtg ttgcgtcagt agacccatct atcaaagtac aagttgacta
     7381 cgctggttca tttggtgatg cggctaaagg taaaacaatt gcagccgcac aatacgcagc
     7441 cggtgcagat attgtttacc aagtagctgg tggtacaggt gcaggtgtct ttgcagaggc
     7501 aaaatctctc aacgaaagcc gtcctgaaaa tgaaaaagtt tgggttatcg gtgttgaccg
     7561 tgaccaagaa gcagaaggta aatacacttc taaagatggc aaagaatcaa actttgttct
     7621 tgtatctact ttgaaacaag ttggtacaac tgtaaaagat atttctaaca aggcagaaaa
     7681 aggagaattc cctggcggtc aagtgatcgt ttactcattg aaggataaag gggttgactt
     7741 ggcagtaaca aacctttcag aagaaggtaa aaaagctgtc gaagatgcaa aagctaaaat
     7801 ccttgatgga agcgtaaaag ttcctgaaaa ataatggatg gaagtcattt cttaggaagc
     7861 ggccaagggc cgctttttta agagttgaga caaagtcatt ttgtctcagt aaagcttgct
     7921 actagacaaa ctagcaagtt ttattgaaat aaaataagac tctgaaagga agagcacatg
     7981 gcacacgaaa atgtcattga gatgcgtgat attaccaagg tgtttggtgg atttgttgcc
     8041 aacgacaaaa tcaacttgca cctacgaaaa ggtgaaattc atgcactttt aggagaaaat
     8101 ggggctggta agtccacgct aatgaacatg ttagcaggcc ttcttgaacc aaccagtggt
     8161 gaaatcgcgg tcaacggtca agttgtcaat ctcgactccc catctaaagc agctagcttg
     8221 ggaatcggga tggttcacca gcactttatg ttggttgaag ccttcacagt ggctgaaaac
     8281 atcattttag gtagtgaatt gactaaaaat ggtgtgctag atatcgctgg agctagcaaa
     8341 gaaatcaagg ctctttctga acgttatggc ttagctgttg acccttctgc caaggtagca
     8401 gatatctcag ttggagccca acaacgtgta gaaattttaa aaacacttta tcggggggct
     8461 gatatcctta tctttgacga accaacggct gttttgactc catcagaaat tgatgagttg
     8521 atggctatta tgaaaaatct tgtcaaagaa ggaaaatcaa ttatcttgat tacccacaaa
     8581 ttggatgaaa ttcgcgcagt ttctgaccgt gttacagtta tccgtcgtgg gaaatcaatt
     8641 gaaaccgttg aaattgcagg ggctatcaat gctgatttgg cggaaatgat ggtaggacgt
     8701 tctgtttcct ttaaaacaaa gaagcaagcc tctaaaccaa aagaagtggt tttgtctatc
     8761 aaagatttgg tggtcaatga aaaccgtggt gttccagctg ttaaaaatct gtccttggat
     8821 gttcgtgctg gagagattgt tggtattgcg gggattgatg gaaatggtca gtctgaactg
     8881 attcaagcca ttacaggtct tcgtaaggtt gaatctggta gcattgagct aaaaggagat
     8941 tcaattgtag gcttgcaccc acgtcagatt acagaactaa gtgttgggca cgttccagaa
     9001 gaccgtcacc gtgatggctt gattttggaa atgatgatat ctgaaaatat tgcccttcaa
     9061 acctactata aagaaccaca tagtaaaaat ggaattttga attattcaaa tattacttct
     9121 tatgctaaaa agctgatgga agagtttgat gttcgcgctg ccagtgaatt agttcctgca
     9181 gctgcactct caggaggaaa tcaacaaaaa gcaattattg ctcgtgaaat tgatcgagat
     9241 cctgatctcc ttatcgttag ccagccaact cgtgggttgg atgtcggtgc cattgagtat
     9301 atccacaaac gcttgattga agagcgtgat aatggcaagg ctgtccttgt tgtcagcttt
     9361 gaattggatg agattttaaa cgtctcagac cgtattgccg ttatccacga tggtaagatt
     9421 caaggtattg tatcaccaga aacaaccaat aaacaaggac ttggtgtctt gatggctggt
     9481 ggaaacttgg gaaaggagaa gagtgatgtc taaaaaatta caacaaattt cggttccctt
     9541 gatttctgta ttcctaggaa ttttactcgg agccattgtc atgtggatct tcggttatga
     9601 tgctatttgg ggctacgaag aattgttcta tacagccttt ggcagtctgc gtgggattgg
     9661 agaaatcttc cgtgctatgg gtcctctggt cttgattggt cttggttttg cggttgccag
     9721 tcgagctggt ttctttaacg tcggacttcc tggtcaggct ttggcaggtt ggattctcag
     9781 tggttggttt gccctgtcgc atccagatat gccccgtccc ttgatgattc tagcaaccat
     9841 cgtgattgcc ttgattgctg gtgggattgt cggagcgatt ccaggtattc ttagggccta
     9901 tctagggacg tcagaggtta ttgtaaccat catgatgaac tacattgtct tgtatgtagg
     9961 gaatgccttt atccatgctt tccctaaaga cttcatgcaa agtacagatt cgaccattcg
    10021 tgttggggct aatgcaacct atcagacacc ttggttagct gagttgactg gtaactcacg
    10081 gatgaatatt ggtattttct ttgccatcat tgccgttgca gttatttggt tcatgctcaa
    10141 gaaaacaact cttggttttg aaatccgtgc agttggtctt aatccacatg cttcagaata
    10201 tgctggtatt tctgccaagc ggactattat cctatctatg attatttcag gtgccttggc
    10261 aggtcttggt ggagctgttg aaggtttggg aaccttccag aacgtctatg ttcaaggttc
    10321 gtcattagct atcggattta acggaatggc ggttagtttg cttgcggcca actcaccaat
    10381 tggtatactc tttgcagcct tcctatttgg cgttctccaa gttggggctc ctggtatgaa
    10441 tgcggcgcag gtaccatctg agctcgtcag cattgtaaca gcgtctatta tcttctttgt
    10501 cagtgttcat taccttatcg aacgctttgt caaaccgaaa aaacaagtta aaggaggtaa
    10561 gtaaagatgt ctattataac cttgctcccc ctcttggtgt cttctatgct gatttactca
    10621 gcacctctca tctttacaag tatcggtggt gttttctctg aacgtggtgg tgtggtaaac
    10681 gttggccttg aaggaattat ggttatgggt gccttttctg gagttgtctt taaccttgaa
    10741 tttgcagaac aatttggagc agcaactcca tggctatcct tgcttgtagc aggattggtt
    10801 ggtagtgttt tctctatcat ccacgcagca gcgacggttc atttccgtgc agaccatgtt
    10861 gtcagcggta cggtattgaa cttgatggcg cctgccttgg ctgttttctt agttaaagtt
    10921 ctttataaca aaggacaaac cgacaaccta agtcaaactt ttggacgctt tgatttccca
    10981 gtcttggcaa atatcccagt gattggtgat atcttcttca agtcaactag tctacttggt
    11041 tatctggcga ttgccttctc attccttgct tggtttattc tctttaagac tcaatttggt
    11101 cttcgtctcc gctctgtcgg tgaacatcct caagcagcgg ataccttggg aatcaacgtc
    11161 tacaagatga gatatttagg ggttattatt tcaggttttc taggtggaat tggcggagcg
    11221 atttatgcgc aatcaatctc agttaacttc tcagtgacaa ctattgttgg acctggattt
    11281 atcgcccttg ctgcgatgat ctttgggaaa tggaatccaa tcggtgctat gctttctagt
    11341 ctcttctttg gactttcaca aagtttggct gttatcggtt ctcaattgcc gttcctacaa
    11401 ggagtgccag cggtttatct tcaaattgca ccttatgttt tgacaattct tgtcttagca
    11461 gccttctttg gaaaagcagt cgcaccaaaa gcagatggta tcaactacat caaatcaaaa
    11521 taagcataca aaaaaacgtc agtccaatga ctgaactgcc ccccaaaagt tagacagaaa
    11581 aaatctaact tttggggtgt ttttattatg aaattaactt atgatgataa agttcagatc
    11641 tatgaactta gaaaacaagg atatagctta gagaagcttt caaataaatt tgggataagc
    11701 aattctaata ttaggtacat gattaaattg attgatcgtt acggaataga gttcgtcaaa
    11761 aaaggaaaaa atcgttacta ttctcctgat ttaaaacaag aaatgattaa taaagtctga
    11821 catgaaggct ggactaaaga cagagtttct cttgaatacg gtctcccaag tcgtacg
//
LOCUS       DBEJJV010000055        11615 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.055, whole genome shotgun sequence.
ACCESSION   DBEJJV010000055 DBEJJV010000000
VERSION     DBEJJV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 11615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.055"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(141..992)
                     /gene="rgg"
                     /locus_tag="ACL3GT_001901"
     CDS             complement(141..992)
                     /gene="rgg"
                     /locus_tag="ACL3GT_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HGR0517508.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNVAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFYTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            1116..1457
                     /locus_tag="ACL3GT_001902"
     CDS             1116..1457
                     /locus_tag="ACL3GT_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HGR0517509.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            1521..1685
                     /locus_tag="ACL3GT_001903"
     CDS             1521..1685
                     /locus_tag="ACL3GT_001903"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517510.1"
                     /translation="MKIKGQTRKLAAGCSKHCFEVMDRTDEVSPKHCFEVVDRTDEVS
                     NHTYGKATLT"
     gene            complement(1711..3414)
                     /gene="ilvD"
                     /locus_tag="ACL3GT_001904"
     CDS             complement(1711..3414)
                     /gene="ilvD"
                     /locus_tag="ACL3GT_001904"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004160 - dihydroxy-acid dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HGR0517511.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(3647..4579)
                     /locus_tag="ACL3GT_001905"
     CDS             complement(3647..4579)
                     /locus_tag="ACL3GT_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HGR0517512.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(4576..5433)
                     /locus_tag="ACL3GT_001906"
     CDS             complement(4576..5433)
                     /locus_tag="ACL3GT_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HGR0517513.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(5437..6783)
                     /locus_tag="ACL3GT_001907"
     CDS             complement(5437..6783)
                     /locus_tag="ACL3GT_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0517514.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(6796..7080)
                     /locus_tag="ACL3GT_001908"
     CDS             complement(6796..7080)
                     /locus_tag="ACL3GT_001908"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0517515.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(7084..9114)
                     /locus_tag="ACL3GT_001909"
     CDS             complement(7084..9114)
                     /locus_tag="ACL3GT_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HGR0517516.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEYYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            9305..10312
                     /locus_tag="ACL3GT_001910"
     CDS             9305..10312
                     /locus_tag="ACL3GT_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HGR0517517.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGVFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            10315..10515
                     /locus_tag="ACL3GT_001911"
     CDS             10315..10515
                     /locus_tag="ACL3GT_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HGR0517518.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            10667..10849
                     /gene="rpmF"
                     /locus_tag="ACL3GT_001912"
     CDS             10667..10849
                     /gene="rpmF"
                     /locus_tag="ACL3GT_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HGR0517519.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            10865..11014
                     /gene="rpmG"
                     /locus_tag="ACL3GT_001913"
     CDS             10865..11014
                     /gene="rpmG"
                     /locus_tag="ACL3GT_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0517520.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(11506..>11615)
                     /locus_tag="ACL3GT_001914"
     CDS             complement(11506..>11615)
                     /locus_tag="ACL3GT_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HGR0517521.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT         3759 a         2443 c         1912 g         3501 t
ORIGIN      
        1 tagcacttat gaatttgcga aacgattctt ttgaatatat gcaacaaaca aaatgagcaa
       61 aaaaacgata gaacttttgt aatgacctga gagagggcaa cagttctatc gcttcaaatt
      121 ttttcttggt ttgcagatac tcaacattcg gtcgtatttc tatagtattc ggcagattta
      181 ttacagccaa gcatctcaaa aatacggaca gcatcctcca tctttttctg accttccttg
      241 actctacctt gcttgctatc aaggagacct tctgcccaca gataaacaat tcggaaatag
      301 gtctcatttt ccttgtagaa atgctcttcg ataacacgtt taaaataata ggcattggta
      361 aattcttcac actcaatact agctaaaaag ccattcaata gtatagtata aaaaaggttt
      421 cgattgccag acatttccat tagaaaatcg gatttacgta ccatttctcg tacatatcta
      481 gtaaaaagag aaacagataa aaatggagaa ctgactgaaa ataaattgag ttcatagatt
      541 ccccagatct cggtagaaaa caaataatca tgaaggactt ttccttcctc tgctgttaac
      601 tctacccttt catccatgct cttcatataa gacttgatca taatggcatt tagaatatgt
      661 ttctgtttgt tgtgagaatg ggcatgcttt tgatactccc tgcgatataa gtcctcaaga
      721 ggtgctacat tctttggttc caagacatct gtaatttctt ttctcaactc agaatctgta
      781 tcatactgga aacctctcgc cagaaagagg atctcctcca cactggcaga tatattttcc
      841 agagcaaata gaaacttttc caccgaaagc tcactctgac ctgtttcaaa acgggacaac
      901 atagacggcg aaaattgtcc tccggttgct tgtctcagtg agatatttct tgactctcgt
      961 aattgtctaa agacttttcc aatctgctcc atagacttcc ccttgattcc gtattttctt
     1021 cattttatca tatttttcag aaaattcatc aaaaacttgc caaattgtca gaattatgag
     1081 aaaatagagg atatttatca cgtggaggga ctgctatgag agacgatatc aaaatcaatg
     1141 accgtgcttt ggccttgcaa gaccaaatca tcgaaaaact agagaaagtt tttgatacag
     1201 atgtggaatt ggatgtttac aatctaggtc tgatttatga aatcaatctg gatgaaacgg
     1261 ggctctgcaa gattgtcatg accttcaccg atactgcctg tgattgcgcc gaaagcctgc
     1321 ctattgaaat cgtggcaggt ctgaaacaaa tcgagggtat caaagatatc aaggttgaag
     1381 ttacctggtc gcctgcttgg aaaatcacac gaatcagtcg ctatggccgt attgcccttg
     1441 gactaccacc tcgttaagca ggccaatcat ttttaaagat gaaaaaagca agccaaaaat
     1501 ggcttgcttt ttgatactca atgaaaatca aagggcaaac tagaaaacta gccgcaggtt
     1561 gctcaaaaca ctgttttgaa gttatggata gaactgacga agtcagccca aaacactgtt
     1621 ttgaggttgt ggatagaact gacgaagtca gtaaccatac ctacggcaag gcgacgttga
     1681 cgtgatttga agagattttc aagtatgagt ttatttttta cctgacttgt ccatattcca
     1741 gaagtctgtc acggctccgc gtgaagcaga tgatacgata tgggcatatt taccgaggac
     1801 accacggctg taaagtggtg gcaaggttgt ttctgccttg cgtttttcaa gttcttcttc
     1861 ggatacggcc atggaaattt ctttggtatc ttggtcaacc gtaacgatat cgccggtacg
     1921 gagataggca attggtccac catcctgagc ttcaggagcg atatgtccaa caaccagacc
     1981 ataagtacca ccagagaaac gtccgtccgt caagagggcc accttatctc cctgaccttt
     2041 accaacaatc attgaagaaa gtgacagcat ctcaggcata ccaggaccac ctttaggtcc
     2101 aacaaaacga acaacgacta catcgccatc aacgatttca tctgtcagaa cggcctgaat
     2161 cgcatcttct tctgagtcaa agaccttagc tggcccaacg tgacgacgca ctttaacacc
     2221 tgataccttg gcaactgcac cgtcaggagc aaggttcccg ttcaagatga taagcggacc
     2281 atccgcacgt tttggatttt caagtggcat gataactttt tggcctggag tcaagtctgc
     2341 aaagtcagcc aagttttcag ctacagtctt accagtacat gtgatgcgat ctccgtgaag
     2401 gaaaccattt gccaacaagt acttcataac cgcagggaca ccaccgactt cgtagaggtc
     2461 ttggaagaca tactgaccag atggtttcaa gtcggccaag tgaggcacac gttcttgaat
     2521 cgtattgaag tcctcaagtg acaagtcaac atttgcggca tgggcaatgg cgagcaagtg
     2581 aagagtggcg tttgtagaac caccgagagc catcgttaca gtaatagcat cttcaaaggc
     2641 ttcacgagtc aagatatctg atggtttgag accaagttcc aacatcttaa caacagcacg
     2701 tcctgctgct tcgatatctt ctttcttatc agctgattca gctgggtgag aggatgaccc
     2761 tggcaaactc atccctagaa cttcgatagc agttgccatg gtattagcag tatacatacc
     2821 accacaacca ccagggccag ggcaggcatt acattcaaga cgtttcacgt cctcagctgt
     2881 catgtcaccg tggttccatt ttccgatacc ttcaaagaca gaaaccaagt cgatatcttt
     2941 accatcaaga tttcccggtg caatagttcc accataggcg aaaatagctg ggatatccat
     3001 attagcaata gcaatcatag atccaggcat gttcttgtca cagccaccga tagcgacgaa
     3061 ggcatccacg ttgtgaccac tcatagccgc ctcgatggag tccgcgatga tgtcacgaga
     3121 tgttagagag aaacgcatac caggcgttcc catagcgatc ccgtccgcta cggtaatggt
     3181 tccaaactgt acaggccaag cgcctgcaga tttgacacct tctttagcca gtttcccgaa
     3241 atcatgcaag tgaatgttac atggtgtatt ttccgcccaa gtcgaaatca ctcccacaat
     3301 cgatgtttca aagtccttat ctgtcatacc agtcgcacga agcatagcac ggttaggtga
     3361 tttaaccatg ctgtcataga tgctactgcg gtgacgttta tctaattcag tcatcttatc
     3421 cctcccattt cagtttttac tattatagca caatttaaag gcaatgaaca gaataaaatt
     3481 cttgaatttt cagaaaattc tatacgcatg tgaaatattt aaaattaaaa acaacaaagc
     3541 ggattagtgc actttctgat gaccagaata tgctttttaa tccgctttct ttaaataacg
     3601 tactgtaatt tttacagaaa ttctttcaga taagtgtatt taacatctat cttgcattat
     3661 aaatttctag aaccttctct tttatattcg attcactcaa accatactca ttaagaagat
     3721 aatccatttt ccctacttga ccgaatcttt cttgaacacc catccgatga atttttgtta
     3781 ttccatcatc agagaataat tcacataaag cactgccaat tccacctatc tgattgtggt
     3841 tttctacagt aaatatagtt tttccactta acattgtttt tatctgttct ggtatcggtt
     3901 tgattctaaa taaatctatc acacttactg aataacctaa tttagacagt tcatctgcaa
     3961 ctcgaatact tggagcaacc attataccag aagcaacgat tacaagatct tcaccatgcc
     4021 ttaactcaat gtagccttta gaaaaatctt ctccaccttg atacacagga actggagctt
     4081 ttctaattgt tcgaatatat tttagtcctt ttaagtctaa tgtctggttc aatatttcac
     4141 gaaattggat atcatcagtt gcttcaaaaa tgatcgattt aggaattaaa cgtaacaatc
     4201 caatttcttc aaatggcata tgtgtcccac cattcatttc tgcagttact cctgcatctg
     4261 atccaatcac agtggcatcc aattgtgcgt atccaagaga aataaataat tgatcaaata
     4321 ctcttcgtga agcaaaagga ccaaatgtat gaagataagg tctaaacccc tgaatagaca
     4381 agcctgctgc aaggccgacc atttctgctt ccataatccc aacattcaca taacggtctc
     4441 caaagtcctt ttcaagatta tgagtagcca tcgaacttga caaatcggct tctaagacta
     4501 ctatatcaga atcactttga ttagcctcta aaaggaagtc tctatataca tgccgtaatt
     4561 ctttcgtgct tctcatcatt ctgtttcctc caattcctga cttaatcttt ctacaactga
     4621 ggttaacatt tgtctctcct ctacagtagg gcgaagatga tgattggatt tcatttcttc
     4681 cagctcttga accccttgac ctttaatagt atctaataca atgcacttag gtgatgaatt
     4741 atttgactgt tttaattgga caatcccttc ataaatttct ctaatatctg aacccttgac
     4801 cctaatggat tcaaatccaa atgctgaaaa tttttctacg aaatcacctg gattacaaat
     4861 atcctttgta aaaccatcta attgtttttt gttatcatca acaaatacaa ttaagttgga
     4921 taactgttga tgagaagcaa actgtatagc ctcccaacat tgtccctcat ttaactcacc
     4981 atctccaaca atagcataag tataaaaggg actctttctt attctctgac catatgcaag
     5041 tccagttgca acactaattc cttgtcctaa agagcccgtt gtcatatcta tgcctggcgt
     5101 tagatttcta tcaggatgag acggtaattt ggttccattt gtatttaaag aatataagaa
     5161 ttctttgtca aagaaaccat tcaaatagag tgtactgtat agagctggtc ctccatgacc
     5221 ttttgataat atgaaataat ctctatctcg tgctgcaaat atttctggag tcattggcat
     5281 tatttcacca taaagcactg ctaaaacttc tacgatagac agacttcctc cgtaatgtcc
     5341 gaatccaaga tgattcaatg ttctaagagt atttaatcgg atgttagtcg caaattttct
     5401 taacccatct tctctatttt tacttaaaat catcccttat tcctcctttg cagatggctt
     5461 tttaataaag gatactccaa acataactgc tagaataaga acaagaccaa tcacaatgcc
     5521 tgcttgtgag ccaaattgat ttaacattcc taaaataatt cctgatagac caaaatctgc
     5581 atctgagaaa gttgatcctt ggaaaccaag tcctcccaaa actggcatta aaaagactgg
     5641 aagaaaactg attaaaatac cttgtaaaaa tgctccaata gtggctccac gaacaccacc
     5701 agatgcattc ccaatgacac ctgcagtcgc tccacagaag aaatgaggca caacacctgg
     5761 taagataaca accgttcctg aagcaatcat aattgccata cttactaaac caccaataaa
     5821 actagagata aatccaatta gaactgcatt gggtgcataa gtataaacaa tcggacaatc
     5881 caaagcaggt tttgaattag gtacaagacg ctctgaaata cctttaaagg ctggaacaat
     5941 ttcgcccaaa ataaggcgaa cacctgctaa aataacaaat acccctgctg caaattgacc
     6001 tgctaattgt aaagcataaa ctagaccact tgtaccacta ctgatttctt tttctatata
     6061 ttctgaccct gcaaagatag ctacaataat gtaaataact gccatggata aagtaatact
     6121 aacagtacta tcacgtaaaa aagctaaact ctttggaaat ttaatgtcct ctgttgattt
     6181 tgatttgtca ccgataaggc taccagtaaa accactcaac caatatccca aagaactgaa
     6241 atgacctaaa gccaccttgt catttccagt taattgaacc atatattttt gaacaaatgc
     6301 tggggaaata ctcataataa taccgagtgc taatcctcct agtaagataa gaggcaagct
     6361 agtaaagcca gcaactgata aaatgaccgc aatcatacat gccatatata gagtgtggtg
     6421 ccctgttaaa aaaatatatt taaatcgagt aaaacgagcg attaagatat tgaacaccat
     6481 gcctgcaaac ataatcagtg cagtagctga gccatatgtt gttaaagcta cagctacaat
     6541 tgcttcatta ttcggcacaa cgccagataa atgaaaagca tgctcaaaca tggtaccaaa
     6601 tggatttaaa gaattttgta caattcctgc accaccagat acaactaaga aaccaacaaa
     6661 ggtcttaatt ccacctttaa taatatcagg taatttcttc ttctgaagaa ctaatcctaa
     6721 aattgcaatt aaagctacta aaatagctgg tgtactaaca atatccaata tgaacttcat
     6781 catgacgcta gcctcctata taagtccttt ttcttcacaa agtttagtaa ttaattctcg
     6841 tagttcatcc atatcaataa tactatttaa gatacgaaca tctccaagat gactagctga
     6901 atcagctaga tcacgaccaa caatccaaat atcagctgca tttggatctg ctccacctaa
     6961 atcataatgt tcaacttcta catctgaaac attcaaatca ctcaatacag attcaatatt
     7021 catctgtacc ataaaacttg aacctaatcc tgaaccacaa gctgtaccaa tttttaacat
     7081 tatctaatcc tcctgtttaa ttatcatttt aatgtcatca tagttttttg atgatattaa
     7141 agtttgaaca tgatttttat ctcttaaaat tgttgttaaa tgtgacaaag cctttaaatg
     7201 actctcatta tcaatggctg caatacaaat caacaatctt acctcttgtt ctggattatc
     7261 caataaataa atcggttctt ccaaaactaa cattgacatt cctatttcat tcacaccttc
     7321 atctggccga gcgtgaggaa ttgctactcc cttccctaaa ttaataaaag gcccaaactc
     7381 ttctactttt tgaatcattg cctcagggta gttctcagtt atcttatctt gatccaaaag
     7441 cggtttagct gctaaacgaa tcgcctcctt ccatcctaat ttttgcgaac taacctgata
     7501 ggtttctttg gtaatgagtt gttctagcac tggtacaatt tcctttctat catttttttg
     7561 gtaaagataa ttctttaacg ccaatcttaa ttccaattct tgtgtaataa ttccatatct
     7621 tttgacaata ttcagaattt gttcaatctc aaaatcccca tactctaaat tcggaaaatc
     7681 ttttaacact agttctacta gttgtattgc ttgctcttca gtcatcataa ccgaaactag
     7741 ataatttggc ttttctgtct ccacctttat ggtagaaaaa accatatcat agtcactact
     7801 agctttcacc tgtaaatcat caatctttga ggttcctata aactcaattt gaggaaataa
     7861 tgctaataga ttctctttta acatcaatga agaactaaca ccattaggac aaatgattgc
     7921 tgctttatac catttttgag gcaaagtatc tgctttcttt aaataacctc cgaaatggat
     7981 aacaaaatat gctgtttcac tatcaggtat gggattgtca atagcgtcca tcaagggcat
     8041 caaagaatct ttgactaatt caaataaatc aggataatat tctttaacat gcaatacata
     8101 ttcatttgaa ctaggtaggc cgaactttaa tctatagtaa gccggtataa ggtggcggcg
     8161 aagattttct ctcaatcctt ccctttgttt aaaatgtaac aaagaaatat cttccattct
     8221 acttataata gcctctgtta attgattaaa gtaaaccgga gcaacatcta cttcaccttc
     8281 aaagcaactt gataataaaa ctgtgatata gcgataatca tcctcagaaa acaccgtatc
     8341 tataattccc aaatcaacca ctgtatccaa taaaatagtg gttatatctt gaataacagg
     8401 agatactaat gtctctgaaa gacatactct ttcaacatcc ctttgatacc tacacagaat
     8461 gaatactaaa ccgaaaaggc aaacttttaa ttgattaaca ataggtacta gttgtagctt
     8521 ctcataataa tctttaacta cctgatttat caaatcataa gttaatgaat acccccaact
     8581 ggataaaaca taatccaaac cccaaatccc tatggaggat tccagcaact cactaaccat
     8641 ttgaaaagct aagcggtgct tattccactc tgaaccgtgt aaagtataac cttttgctct
     8701 actgtaccct agctccaaat cattatctaa cataatcttt cttaatgatt gaatatcaga
     8761 taaggttgta ttcttactta ctttcaaaaa gtcttggtaa tgattattcg atataaaatc
     8821 taatcggcaa aaagtgtaaa gatagattaa agctaagcga gtcgactttg gtaaaaccaa
     8881 ttcatccgac ttaataatat ctgtcaaaga ctgcttcgta cgatttgata aactatagcg
     8941 accttgtttt ttatccagca ctatcccttt attagctaga taaggcacta aataatctat
     9001 tccttctttg acttccttta taggtaagct caccttaaca gataattcat ataatgatag
     9061 ctcacaatga tccatcaaag tcatcaaaat aactagtgct ctataatcaa acatttctct
     9121 tcctttctaa ctacaattat agtgtaaaaa ttataagaat aaaagagtat ttgagcacaa
     9181 tataatctca ccttttaaaa gaaattattg ggctgaaagt ttttagtgat tattttcaac
     9241 tttctattga cttttaaaaa caaagtgata tcatttagat atcaaataat gggaggtcat
     9301 tcttatgact gaaaaactaa tcaattcaaa accaaatggt gtattcgcat tgattctcat
     9361 tgagttgaca atcgtacttg gtgtctttat atttataatg ggtgttggtt cggaaaacat
     9421 ttttggaatt attatcggac ctttactaat cgtaattgca ggtctagctc atgctggttt
     9481 aaaagttgtc aaacctcagg aagctctggt tctgacactc tttggtaact atacaggtac
     9541 catcaaagaa cctggttttt actttgtcaa tcccttcagc gtagcagtca accctgcaaa
     9601 ccacactcga cttggacaaa gtggtgatgt tagcacaaaa tctccttttt taggagctaa
     9661 atcatcaaat gacaatgatg taaatcttga aattggcaag aaacagattt ccctcaaagt
     9721 catgaccttg agcaattctc gtcaaaaaat caatgattgc ttaggaaacc ctgtagaaat
     9781 cggtatcgcg gtaacttgga gagttgtcga taccgctaag gcagtcttca acgttgataa
     9841 ctacaaagaa tatctttcat tgcaatgtga tagcgccctc cgtaatattg tccgcatcta
     9901 tccttacgat gtgtctccta atgtggatac tacgggtgac gggcaagcag atgaaggtag
     9961 tctccgtggc tctagcgaaa ttgttgctaa ccgtattcgt gaagaaatcc aaagtcgtgt
    10021 tgaggatgct ggcttggaaa tccttgaagc acgtatcact tacctagctt atgctccaga
    10081 aattgctgcc gttatgcttc aacgccaaca agcatctgcc attattgatg cacggaagat
    10141 gattgtagat ggtgctgtag gaatggttga aatggcacta gaacggctca atgaagggga
    10201 attggtagaa cttgacgaag aacgaaaagc tgccatggtt tcaaatctcc ttgtcgttct
    10261 ttgtggcaat catgatgcac aaccaattgt caacacagga agtctttact aaagatggct
    10321 gaagctaaaa aaaagcagat cccccttcga ctctcaacaa agttatacgc tgcactcgca
    10381 tcatgggcag aagacgactt tcgttcagtc aatgggcaaa tcgaatatct cctcacagag
    10441 tgtgtcaagc aacggaagaa agacggaaaa tacgtatcag aaaccattga cgaaccattt
    10501 gagattgata tttaacatct tctcctgtct gacaagtcgg acaggagaat tttttcatct
    10561 ttttttgtca agtaacttta ctttacaaaa aaaatgtgtt atcctagtat ggttgatgaa
    10621 aatcagtaga ttgaatcgaa tataaatacc taaaggagaa atcaaaatgg cagtacctgc
    10681 acgtcgcact tcaaaagcga agaaaaacaa acgtcgtaca cactacaaag taacagctcc
    10741 atctgtaaac tttgacgaaa ctactggaga ttactcacgt tctcaccgtg tatcacttaa
    10801 aggatactac aaaggacgta aaatcgctaa agctgcatca gctgaataat agaagggaga
    10861 taccatgcgc gtaaatatta cacttgaaca caaagaatct ggtgaacgct tgtaccttac
    10921 ttctaaaaac aaacgtaaca ctccagaccg ccttcaattg aagaaatact caccaaaact
    10981 tcgcaaacac gttgtgttta cagaagttaa gtaagcattc aatacgaatc aatacagaag
    11041 aaaaacgctt gatcagcgtt ttttcttttt gttaatttca ctatattgca agggaaatca
    11101 ttcgaatgac tacatttttc actacctttt ttgaaataag aatacggatt cggacgatta
    11161 aaagtaagag aaactcaaat gtaagttggg gttccttttt tgtatatttt tcaaataacg
    11221 cctctacact atttgtagca aattcaccaa ctacagttgt atcttagtta aaataagtta
    11281 gaatatgtaa gtgagtacca gatataccaa gacatcgtca ccatctaagg tatattcaaa
    11341 atacaaaagt tgaccaacta gatttctgaa tatccttata tatccattct taaaattggt
    11401 ttaaatagcg tagtctttta aactagtttt gagaatccaa aaaatcttcc tacatatgta
    11461 agaagatttt ttagttcaga atgattagat ttagctaatg gatacctatc ctacccactc
    11521 accgttagca ttgactcgat agccatcggg tgtagtcgtg tttactaata aatctcctga
    11581 attataggta tagtaccatt taccagaaac tgtaa
//
LOCUS       DBEJJV010000056        10782 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.056, whole genome shotgun sequence.
ACCESSION   DBEJJV010000056 DBEJJV010000000
VERSION     DBEJJV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10782
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.056"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..174)
                     /locus_tag="ACL3GT_001915"
     CDS             complement(<1..174)
                     /locus_tag="ACL3GT_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR0517522.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKPR"
     gene            345..500
                     /locus_tag="ACL3GT_001916"
                     /pseudo
     CDS             345..500
                     /locus_tag="ACL3GT_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            700..3975
                     /gene="rexB"
                     /locus_tag="ACL3GT_001917"
     CDS             700..3975
                     /gene="rexB"
                     /locus_tag="ACL3GT_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HGR0517523.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3972..7622
                     /gene="addA"
                     /locus_tag="ACL3GT_001918"
     CDS             3972..7622
                     /gene="addA"
                     /locus_tag="ACL3GT_001918"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HGR0517524.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKANFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7837..9015
                     /locus_tag="ACL3GT_001919"
     CDS             7837..9015
                     /locus_tag="ACL3GT_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517525.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            9224..>10782
                     /gene="iga"
                     /locus_tag="ACL3GT_001920"
     CDS             9224..>10782
                     /gene="iga"
                     /locus_tag="ACL3GT_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HGR0517526.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEAPKEYTG"
BASE COUNT         3429 a         2171 c         2276 g         2906 t
ORIGIN      
        1 tcttggtttt gttcctttta cttggtgatt tagctctcct gttttctctt ttagctttaa
       61 ccagccataa atggtattac gtgagatttg gaaaacgtgt gatgcttctg ttatactacc
      121 tgttcgctca caataagaga gaactttttt acgaaaatct attgaatatg ccataagaag
      181 attataccac attgtgtact atttttggtt cattttacta tagtagattg aaataagata
      241 cgaacagctt gattagggaa atcaaattaa tttctagaaa tattttagca tccacggtgt
      301 actattatag tttcaattta ctatagttca atcattctat caagaatatt gaatatataa
      361 aggcacgtaa tattaaaact tcttctgata tcgaattaga gtccgatgtt gatggcgata
      421 aatcagacaa tctaccagtc gacattaaga tactgggaca acacattgaa gtgtattccg
      481 tacctaagaa acaatcataa aactcaaagc cttgttaccg aggctttttt attatgtgat
      541 tttcagtagc cagacttatt ctatctaata caagtaaagc taagtattta agatttagca
      601 gatgatgaag aaaagaaagg atggcctaaa tattttaaca gatttacgag gctaatcatg
      661 gtataatata gggtgatgaa aaattccaac gaggctgaga tgaaattact ttatactgat
      721 attcggactt ctttgacaga aattctaaca agagaggcag aagagctagt tgcagctggc
      781 aagcgggtct tctacattgc ccccaactct ctttcttttg aaaaggaacg cgccgtgctg
      841 gaatgcttgt cccagcaggc ttctttttcg attaccgtca cgcgctttgc tcaaatggct
      901 cgttatctgg tcttgaatga tttaccagct aaaactactc ttgatgatat cggtcttggg
      961 ttggcctttt acaaatgcct tgccgaactc gatcccaagg acttgcgtgt ttatggcgct
     1021 attaagcagg atcctcaatt gatccagcag ttaattgagc tttatcatga gatgaccaaa
     1081 tcccagatga gttttttgga cttggagaat ttaacagatg aggataagag ggcggattta
     1141 ctcttgattt ttgagaaagt aacagcctat cttaatcaag gtcagttagc ccagggaagt
     1201 cagttgtccc atttgattga ggctattgag aatgacaagg taagtagtga ttttaatcaa
     1261 atcaccttgg tcattgacgg ctttactcgt ttttctgctg aggaagagcg ggttgtggac
     1321 ttacttcacg gcaaaggtgt tgagattgtt atcggggctt atgctagtaa gaaagcctat
     1381 accagtcctt ttagcgaggg caatctctac caagccagcg taaaatttct ccatcatctg
     1441 gcttctaaat accaaacgcc tgctcaggac tgttctcaaa ctcatgagaa gatggatagt
     1501 tttgacaagg cctctcgttt gttggagtct tcttatgact tttcagaact cgctttggat
     1561 gtcgatgaga aagaccgtga aaatttacaa atctggtctt gtttgacgca aaaggaggag
     1621 ttggagctag tagcccgtag tattcgtcag aaattacatg agaactcaga cctgagctac
     1681 aagcattttc gtattctctt gggggatgta gcttcttacc agttatctct caaaaccatt
     1741 tttgaccagt atcagattcc tttttatctt ggtagaagcg aagccatggc tcatcatccc
     1801 ttgactcagt ttgtcgagtc tattttagct ttaaaacgtt accgttttcg tcaggaggat
     1861 ttgattaatc ttcttagaac tgatttgtat actgacctca gtcagtctga tattgatgct
     1921 tttgagcaat atatccgcta tcttggtatc aatggcttgc cagcctttca gcaaatcttc
     1981 accaaatccc accatggaaa atttaatctt gagcgtttga atgtcctccg cctgagaatt
     2041 ttagcacctc ttgaaaccct ctttgccagc cgaaaacaaa aggctgaaaa cctcctacaa
     2101 aaatggagtg tctttctaaa agaaggagct gtgaccaagc agttacaaga tttgacaacc
     2161 actttggaag ctgtagaaca ggaaagacaa gccgaagttt ggaaggcttt ctgccatgtt
     2221 ttagaacaat ttgcgactgt ttttgctggt tcacaggtta gtctggaaga cttcctagcc
     2281 ttgctccatt ctggaatgag tttgtcccaa taccgtacca ttccagcaac agtggacact
     2341 gttctggtgc agagttacga tttgattgca ccattgactg ctgactttgt ctatgctatt
     2401 ggactaactc aggacaattt accaaaaatt tctcaaaaca ccagtcttct gacagatgaa
     2461 gaaaggcaaa acctaaacca agcgaccgaa gaaggcgttc aattactgat tgccagcagt
     2521 gaaaatctca agaaaaatcg ctacactatg ctttccttgg tcaattctgc tcgtaagcag
     2581 ttgttcttgt cggctccaag cctttttaac gaaagtgaaa gtaaggaatc tgcctatctt
     2641 caagagttga tccattttgg atttaggcgg agagagaaga ggatgaatca caaaggactg
     2701 tctaaggagg atatggggtc ctatcacagt cttttgtcta gtctggttgc ctatcaccag
     2761 cagggtgaga tgagcgatac tgagcaagat ttgacttttg tcaaggttct gtcgcgtgtc
     2821 ataggtaaaa aactagatct gcaaggtctg gaaaatccag ctatcccaac cagtccaagc
     2881 agcaagacct tagccaagga caccttgcaa gctctctatc ctgccaaaca ggagttttac
     2941 ctgtctacgt cgggtttgac agagttttat cgcaatgaat acagttattt cctacgctac
     3001 gttttaggct tgcaggagga attacgtttg cgtcctgatg cccgtagtca cgggaatttc
     3061 ttgcatcgta tctttgaacg cgccttacag ttgcctaatg aagattcctt tgaccaacgt
     3121 ctagaacaag ctattcaaga aaccagtcaa gaacgcgaat ttgaagctat ttatcaagaa
     3181 agtttggaag cccagtttac caaggaagtt ttgcttgatg ttgcacggac gactggacat
     3241 attctccgac acaatccagc catcgaaacc atcaaagaag aagcaaattt tggtggaaaa
     3301 gaccaagcct ttattcaatt agacaatgga cgcagtgtct ttgtacgagg caaggtggac
     3361 cggattgacc gtttgaaagc taatggagcg ataggagtag tagactacaa atccagtctg
     3421 actcagttcc agtttcctca tttctttaat gggctcaatt ctcagttacc aacctatctt
     3481 gctgccctaa aaagagaagg gaagcagaac tttttcggcg ccatgtactt ggaaatggct
     3541 gaacctgtcc aatctctgat ggcggtaaaa agtctggcag gagcagtggt agaagccagc
     3601 aaatctatga aataccaagg gctcttcttg gaaaaagaaa gcagttattt aggcgaattt
     3661 tataacaaaa acaaggctaa tcaactgaca gatgaggaat ttcagctcct actggactac
     3721 aatgcctatc tttacaagaa agctgctgag aagattttag caggccggtt cgccatcaat
     3781 ccttatactg aaaatggcag aagcattgcc ccatacgtcc agcaacatca ggctattaca
     3841 ggctttgaag ccaattacca tctgggccaa gcccgtttcc tagaaaaatt ggacctagct
     3901 gatggcaagc gtctggtcgg agaaaaactc aagcaagctt ggtttgaaaa aataagagag
     3961 gagttaaatc gatgaagctt attccctttt taagtgagga ggagattcaa aaactgcaag
     4021 aagcagaagc aaattcgagc aaggaacaga agaaaactgc cgaacaaatc gaagctatct
     4081 acacttctgg tcagaatatc ctggtctcag catcggctgg ttctggaaag acctttgtca
     4141 tggcagagcg cattctggac caattggcgc gtggtgtcga aatttctcaa ctctttatct
     4201 caacctttac cgtcaaggct gcaactgaac ttaaagaacg tttagagaaa aaaatcagca
     4261 agaaaatcca agaaacagat gatgtcgatc tcaaacaaca cttgggtcgc cagttggcag
     4321 acctacccaa cgctgccatc ggaaccatgg actctttcac acaaaaattc cttggcaaac
     4381 atggttatct gcttgatatt gcacctaatt tccgtatttt acaaaaccaa agcgagcaac
     4441 ttcttctcga aaacgaagtc tttcatgagg tctttgaagc gcattaccaa ggtaaacaga
     4501 aagagagctt tagtcatttg ctgaaaaact ttgctgggcg tggcaaggac gaacggggtc
     4561 tgcggcagca agtctataaa atctatgact tcctccaatc caccagtaat cctcaaaagt
     4621 ggctgagtga atctttcctc aaaggctttg agaaagctga ttttaccagt gaaaaagaaa
     4681 aactgactga gcaaatcaaa caagccctct gggatttgga aagctttttc cgttaccatc
     4741 tggataacga tgccaaggag tttgcaaagg ctgcctattt agaaaatgtt cagttaattc
     4801 tggatgaaat tggctcccta aatcaggagt tcgatagtca ggcttatcag gcagtacttg
     4861 cgcgtgttgt cgccatctct aaggagaaaa acggtcgtgc tctgactaat gccagccgta
     4921 aggctgattt gaagcccctg gctgatgcct acaacgaaga gagaaagacc cagtttacta
     4981 aactaggaca attatcagac cagatagcga ttctcgacta tcaagaacgt tatcatggag
     5041 acacttggaa actagctaaa accttccaat ctttcatgag cgattttgta gaggcttatc
     5101 gtcagagaaa acgacaggaa aatgcctttg aattcgctga tatcagccat tacaccattg
     5161 agattttaga gaatttccca caagttcgtg agtcttatca ggagcgcttc catgaagtca
     5221 tggtcgatga gtatcaggat accaaccata ttcaagaacg gatgctggaa ttgttgtcta
     5281 atggccacaa tcgctttatg gtgggagata tcaagcaatc catctatcgt ttccgtcagg
     5341 cagacccgca gattttcaat gagaaattcc aacgctatgc gcaaaatccc caagaaggca
     5401 agctcattct cctcaaggca aatttccgta gtagttcaga agtgctgtca gcaaccaatg
     5461 atgtctttga acgtctcatg gaccaagagg tcggcgaaat caactatgat aacaagcacc
     5521 agcttgtttt tgccaatacc aaactgactc ccaatccaga caacaaggca gaatttctcc
     5581 tctacgacaa ggacgataca ggtgaggaag aagagagtca aacagaaacg aaactaacag
     5641 gcgaaatgcg cttagttatc aaggagattc tgaaacttca tcaagaaaaa ggtgttgcct
     5701 ttaaggaaat tgcccttctg acctccagcc gcagtcgtaa tgaccagatt ctcctcgccc
     5761 tgtctgagta cggaattcct gtcaaaactg acggagagca aaacaattat ctccaatccc
     5821 tagaagtgca agtcatgcta gacactcttc gtgtcattca caatcccctg caagactacg
     5881 ccttggttgc ccttatgaag tctccaatgt ttggttttga tgaggatgag ctagcacgtt
     5941 tgtcccttca gaaagcagag gataaagtcc acgaaaatct ctatgagaaa ctggtcaatg
     6001 cacaaaaaat ggcaagtagt caaaaaggct tgattcacac agctctagct gaaaaactaa
     6061 agcaattcat ggatatccta gcttcttggc gcttgtatgc caaaacccac tctctctatg
     6121 acttgatttg gaagatttac aacgaccgtt tttattatga ctatgttggg gctttgccga
     6181 atggtcctgc taggcaggcc aatctctatg ccctagcact gcgtgctgat caatttgaaa
     6241 agagcaattt caaaggtttg tcgcgtttta ttcgtatgat tgaccaagtc ttagaagccc
     6301 agcacgattt ggcaagcgtg gccgtcgcac cgccaaaaga tgcagtagag ctcatgacca
     6361 tccacaagag taaagggctg gagtttcctt acgtctttat cctcaatatg gatcaagatt
     6421 tcaacaagca agactctatg tcagaagtca ttctcagtcg tcagaatggt cttggtgtca
     6481 aatatattgc caagatggag acaggggcag tagaagacca ctatcctaaa accatcaaac
     6541 tctccattcc tagtctgacc tataggcaga acgaagagga attacagcta gcaagctatt
     6601 ctgagcagat gcgtttgctg tatgttgcta tgacgcgggc tgagaaaaag ctctatcttg
     6661 tcggcaaggg ttctcgtgaa aagctggaag tcaagcaata cccagcagcc aaaaatggga
     6721 aactaaatag caatactaga ctgcaagcac ggaatttcca agattggctt tgggctatca
     6781 gtaaagtgtt tactaaggac aagctcaact ttagttatcg ttttattggc gaagatcagt
     6841 tgaccagaga agctatcgga gagttggaaa ccaagagtcc tctccaagat agctcccaag
     6901 cagacaatcg tcagtcagat accatcaaag aagctctgga aatgctgaag gaggtggaag
     6961 tttataatac tcttcaccgc gcagctattg aacttcctag tgttcaaacc ccaagtcaaa
     7021 tcaagaaatt ctacgaacca gttatggata tggaaggtgt cgagattgct ggtcaaggtc
     7081 agtcagtagg caagaaaatc agcttcgatt tgccagattt ttcaaccaaa gaaaaggtaa
     7141 ctggagctga gattggtagt gctactcacg aactcatgca gagaattgac ctcagccagc
     7201 aactaaccct tgctagccta acagaaacac tcaaacaagt tcaaactagc caagctgtca
     7261 gagacaagat caatcttgat aaaattcttg ctttctttga cacagtactc ggtcaggaaa
     7321 ttcttgctaa taccgaccat ctctatcgcg agcaaccttt ctccatgctc aaacgagacc
     7381 aaaagagtca ggaagacttt gttgtccgtg gtatccttga tggctatctg ctttacgaaa
     7441 acaaaattgt tctgttcgac tacaagacag accgctatga tgaaccaagt caactcgtag
     7501 accgctatcg tggtcagtta gctctatacg aagaggcttt atcacgagcc tattcgattg
     7561 aaaatattga aaaatacttg attttactcg gtaaagacga ggttcaagtt gtaaaagtat
     7621 aacttatact ctttgaaaat ctcttcaaac cacgtcagct tcgccttgct gtatatatgg
     7681 ttactgactt cgtcagttct atccacaacc tcaaaacagt gttttgagct gacttcgtca
     7741 gttctatcta caacctcaaa acagtgtttt gagctgattg cggctagctt tctagtttgc
     7801 tctttgattt ttattgagta ttagaaagga gacctcatga cacttccagt tagaaaatcc
     7861 ctgcacgatg cagttttaca ggcttcgaaa gcggatactt gggaacaagc taccaaggaa
     7921 tggaatgaag tttccttgat ttttaacggt atcggccgta gcaattgtgt ctgtggaaat
     7981 gccatcaaat acgcttatga actctttaac ggtgtcacag gccaacgcct ctttccaatt
     8041 ggtagcgact gtgttcgtca ttttcatcga ttgtcccttg accagcaatt ggaagaggaa
     8101 gaaaaactgc tcagaaaggt tgaaaatcta accagaaaag ctcagaaaaa ggaaaaaatc
     8161 aaggtcaata aaagtgactt tgacgagcga cttctaaaat ggctctggga aaaaggtgtt
     8221 ttcaaaccca atcgtggcaa tcaatttgcg cctgagagag actaccagct tttcctagaa
     8281 gtctttcagg gaggaagttg gaccaaggcg gaaccaaaga aaaaggctcg gatggaagaa
     8341 gtccttgaaa agtgtatcaa acccttttta cttgggaaat cggatgacca actctacctt
     8401 gtcaagctag gcaaggagaa aattgactac gaacaagaac tccgtatcca ggcagagaaa
     8461 gaacgcaaga agagggataa aatcgccaag caatatgcag acaatctggt tctagccatg
     8521 ggacccgcag agcgtgctta tcaagattac tttggcttta cagagaccct gactcaagaa
     8581 gaacgcaagt gggaaaaaat tctttttggt aaaaatagag cagaacgggc tatcaaggcc
     8641 aaacaatacc aaaaagagct ggaaaaagac caacgaattg ccagtcagga tccaattgaa
     8701 agaaaacaga agcagacttg gctcctcaat tcctattttc gtgagcttcc tgaagaaaaa
     8761 gctcgatttt ctaggctctt attagaatat cgaaaaagtg gtgaagtacc cttttcaact
     8821 gaatacctgt ccgatcatct catcgacttt ttctataaaa tgaaagcctt tgaatttgaa
     8881 atcgcaccag aacaagtccg agattttcta aaaaaaagcc tgcaggaaga ccatcgctca
     8941 tcagcacaag gaagctggat agaaggaatt ctcctcaact gcctcaaacc atttttagaa
     9001 cgattagtga tatgagtaac acctaccgtg taaatttcat ggtaggtgtt attgtacccc
     9061 caaataatat aaaacaaagt atgaaagcgc atctcaattt taagactttt ttgtaaatta
     9121 agagtataat taaggtatac tgccttttct atagataata gataatacac taatataata
     9181 aaggtctttg taacatatat aaattttatt tcaaggagga ataatggaaa agtattttgg
     9241 tgaaaaacaa gagcgttttt catttagaaa attatcagta ggacttgtat ctgcaacgat
     9301 ttcaagttta ttttttatgt ctgtattagc tagttcatct gtggatgctc aagaaactgc
     9361 gggagttcac tataaatatg tggcagattc agagctatca tcagaagaaa agaagcagct
     9421 tgtctatgat attccgacat acgtggagaa tgatgatgaa acttattatc ttgtttataa
     9481 gttaaattct caaaatcaac tggcggaatt accaaatact ggaagcaaga atgagaggca
     9541 agccctagtt gctggtgcta gcttagctgc tctgggaatt ttaatttttg ctgtttccaa
     9601 gaaaaaggtt aagaataaaa cggtattaca tttagtattg gttgcgggaa tgggaaatgg
     9661 tgtcttagtt tcagtccatg ctttagaaaa tcatcttttg ctaaattaca atacggacta
     9721 tgaattgacc tctggagaaa aattacctct tcctaaagag atttcaggtt acacttatat
     9781 tggatatatc aaagagggaa aaacgacttc tgattttgaa gtaagtaatc aagaaaaatc
     9841 agcagccact cctacaaaac aacaaaaggt ggattataat gttacaccaa attttgtaga
     9901 ccatccatca acagtacaag ctattcagga acaaacacct gtttcttcaa ctaagccgac
     9961 agaagttcaa gtagttgaaa aacctttctc tactgaatta atcaatccaa gaaaagaaga
    10021 gaaacaatct tcagattctc aagaacaatt agccgaacat aagaatctag aaacgaagaa
    10081 agaggagaag atttctccaa aggaaaagac tggggtaaat acattaaatc cacaggatga
    10141 agtgctatca ggtcagttga acaaaccgga actcttatat cgtgacgaaa ctatagaaac
    10201 aaaaatagat tttcaagaag aaattcaaga aaatcctgat ttagcagaag gaactgtaag
    10261 agtaaaacaa gaaggtgcat taggtaagaa agttgaaatc gtcagaatat tttctgtaaa
    10321 caatgaagaa gtttcacgag aaattatttc aacttcaacg actgcgcctg tttcaagaat
    10381 agtcgaaaaa ggtactaaaa aagctcaagt tataaaggaa caagctgaga ctggtgcaga
    10441 acataaggaa gtacagtctg gagctattgt tgaacccgca attcagcctg aactaccagc
    10501 agctgtatta accgacaaag gtgagtcagc agtccaacca gagttgccag aagctgtagt
    10561 aagtgataaa ggcgtaccag aagttcaacc agcgttacca gaggcagtca tgactgacaa
    10621 gggtgatcca gagcaggtag caccactacc agaatacaca ggggtgcaag ccggagcgat
    10681 agtcgagcca gagaaagtag aagcaccgaa ggaatacaca ggagtgcagg ctggagcgat
    10741 agtcgaacca gagaaggtag aagcaccgaa ggaatacaca gg
//
LOCUS       DBEJJV010000057        10733 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.057, whole genome shotgun sequence.
ACCESSION   DBEJJV010000057 DBEJJV010000000
VERSION     DBEJJV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10733
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.057"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(78..1292)
                     /locus_tag="ACL3GT_001921"
     CDS             complement(78..1292)
                     /locus_tag="ACL3GT_001921"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0517527.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1448..1742)
                     /locus_tag="ACL3GT_001922"
                     /pseudo
     CDS             complement(1448..1742)
                     /locus_tag="ACL3GT_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1904..2356
                     /locus_tag="ACL3GT_001923"
     CDS             1904..2356
                     /locus_tag="ACL3GT_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HGR0517528.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2391..3779)
                     /locus_tag="ACL3GT_001924"
     CDS             complement(2391..3779)
                     /locus_tag="ACL3GT_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HGR0517529.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3845..4807
                     /locus_tag="ACL3GT_001925"
     CDS             3845..4807
                     /locus_tag="ACL3GT_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HGR0517530.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(5013..6023)
                     /gene="ccpA"
                     /locus_tag="ACL3GT_001926"
     CDS             complement(5013..6023)
                     /gene="ccpA"
                     /locus_tag="ACL3GT_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HGR0517531.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLVKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6447..7046)
                     /locus_tag="ACL3GT_001927"
     CDS             complement(6447..7046)
                     /locus_tag="ACL3GT_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HGR0517532.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLAFQADVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7047..8144)
                     /locus_tag="ACL3GT_001928"
     CDS             complement(7047..8144)
                     /locus_tag="ACL3GT_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HGR0517533.1"
                     /translation="MLERLKSIDYMYWASLIFMIFPILPVVTGEIPSWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERAEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVSPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8144..8881)
                     /locus_tag="ACL3GT_001929"
     CDS             complement(8144..8881)
                     /locus_tag="ACL3GT_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0517534.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTAMFSFPAVLHTDKINNWQKTLRHTPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHFVRGVDMPLGSWIGAAFLLIVGSVAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGGINL
                     SATVYILVFSAVLFGLTIYLQGHKENA"
     gene            complement(8883..9767)
                     /locus_tag="ACL3GT_001930"
     CDS             complement(8883..9767)
                     /locus_tag="ACL3GT_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0517535.1"
                     /translation="MNMIKVESLNKNIKGKAILKGISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLSVTSSQLDYIRGYLPQENVIVQKLKVKELIAFFQRIY
                     PNSLSDQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     GIEKHFILPLAYKEVIEQSNLVENWSQKQDALQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(9754..9948)
                     /locus_tag="ACL3GT_001931"
     CDS             complement(9754..9948)
                     /locus_tag="ACL3GT_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517536.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTGWFDQTLLRQFIRGALGFGFM
                     IFVVFLMRMEWLKGEYHEYD"
     gene            complement(9945..10151)
                     /locus_tag="ACL3GT_001932"
                     /pseudo
     CDS             complement(9945..10151)
                     /locus_tag="ACL3GT_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3276 a         2448 c         1935 g         3074 t
ORIGIN      
        1 aaaatgcttg gactacaagt cgccaagtga atttcttttg ggtggctaac ttcaacttga
       61 aatttgggat gcaagcccta tctacgatac tgtttcaaga aacgagtcat cttttcttgg
      121 atttgggcta actcatcaac acgaggaagg taaacgatac ggaagtggtc tggttcctgc
      181 cagttaaagc ctcgaccatg aaccaagaga accttttcct gcttcaagaa atcaaggaca
      241 aactgctcat catcatcgat acggtacata ttgcggtcga tttttgggaa gatatagagc
      301 cccgccttgg gtttaacggc agacaaacct ggaatatctt gaatggcatt atagatgaaa
      361 tttctttgct cgtagattcg tccaccagga agaagcaatt catcgactga ttggtgaccc
      421 cccaaggaag tttgtacgac ttgttgggcc aaaacgttag agcaaaggcg catattggac
      481 agcatattga gcccttcgat atagccctta acatgagtct tagggccaga caagaccatc
      541 caacccacac ggaaacctgc tatgcggtgg gattttgaca gaccattcat gctgacacag
      601 aagacatctg gtgccaagct cgccacaggc gtatgcacat gtccgtccat taccatgcgg
      661 tcatagattt catccgcaaa gataatcaaa tcgttttgac gggcaatctc aataatctcc
      721 agcaagagtt ccttaggata aagggctcca gttgggttat ttggattgat aaggacaatt
      781 gccttggtat tggaagtgat ttttgacttg atatcgtcaa tatctgggta ccattccaca
      841 gcttcatcac agatatagtg aacggcattt cctccagcta ggctgacagc cgccgtccat
      901 agaggatagt ctggcattgg cactaagacc tcatccccat tgtccaaaag cccctgcatg
      961 gacatgacaa tcaactcact gacaccattt ccaaggtaaa tatcatcaat atctacgttt
     1021 gggaatttct tcagctggca atactgcatg atggccttac gggctgagaa aatccctttg
     1081 gagtcagaat agccttcact atcacgcgca ttcataatca agtcatgaat gacctcgtct
     1141 ggcgctgtaa agccaaattc tgctggattt cctgtattca gacgtaaaat cttttctcca
     1201 ttcgctcgca tccgcatggc ttcttccaat acaggaccac ggatatcata agcaacatgc
     1261 tctaacttac tagacttgtt atattctttc atcttgtttc ctcaattcat caggatagta
     1321 acattatacc actagaaaga gaatgcgaca agtttactga aatgtgttac tagtttcgta
     1381 tagaagaaaa accttgctaa aggcgaggtt aagaacgtag agatagcagg tattttgcaa
     1441 agacacatca cataccaaaa gataaaccta gaaaaaagca agcctagaaa ggagtcataa
     1501 agaagattaa acatgaggaa aagcccccat atcatcaagt aatcccaacg cccacttcgt
     1561 tttgcaacta gaaataagat tagatggtag agtacatgaa aaactaaaaa tccaataaaa
     1621 cttggataaa gaagcggtac cagactctct aattgacaga tcatgatcac ttctaccaag
     1681 actgaaacta ggataattcc ataataaagg aaatttgatt tttgaaaaga gtttttcatc
     1741 attctccctt ccttcacttc tttcctgcta tcctttcttt tattttatca tatatttata
     1801 tagagtttaa gccctaatat tcttttgaaa aatacttttt ttgctttact tctatagtga
     1861 aaaggtttac aattatagta agaaaatttc aggaggtttc attatggcac aacgttacca
     1921 aaatatcatg gtcgcaatcg atggttctaa ggaagcggac ttggcttttg tcaagggagt
     1981 tcattctgct ctacgaaacg acgctaaact caccatcgca catgtcattg acacacgcgc
     2041 tctccaaagc gtatccacct ttgatgctga agtttacgaa gaactccaag tcgacgctga
     2101 aagtctgatg aaagagtacg aaaaacgtgc taaagatgct ggggtagcag atgttcatat
     2161 cgtcattgaa atgggaaatc caaagaccct gctagcacgt actattccag atgccgagga
     2221 agtggacctc atcctcgttg gcgcaactgg tctcaacgcc tttgaacgcc tcttggtcgg
     2281 ctcttcatct gaatacatac tccgccatgc taaggtcgat ttgctggttg tgagagaaca
     2341 agaaaaaacc ttataatcac aaagaaaagg agcccctagc tcctttttgt ttacgattta
     2401 tttctctctt tatggcgttc gtaagccttg agctggcgct gcagttcctt tttaatagca
     2461 ggttctggag catatttttc ttcccaatta tctggtttta agattttatg ggtcactgga
     2521 tcaaaatgag ccttgccatc tggaaaaatt ttccccatat tggcctgatg gacaatatca
     2581 aaaatacgtt ctgggtccac ccccatcaag acaaaactgc cgtaggtgaa gtaaagcgtg
     2641 tcaatcaagg catccacttg ccctatcaaa tcttgctgag caggtgtctt cttggctact
     2701 ttacctgctg ccttatcaag ggcctgatga agttgcgata cagcttgacc aaaatcttct
     2761 tcagaaggac tggctgatcg aacaaactcc accaattctt ctattttaaa accagcccta
     2821 tgggttgcac cctctaaatc ccaagctcga ggttcttctt gggttcgttc atccatcatg
     2881 tggtggaagg tcttgacctt attgaaatga tagtcacggc tgacaaaaac tttttctgaa
     2941 gacaaaacac caaaatgttc caaggccttg tggatcccat cttgttgatt gctagtggta
     3001 atgtgcttgg cagcttcctt gacactgcta ctaccatttc ccatagcgac cgacataccg
     3061 acgccagcca gcatttcaag gtcattatct gagtcaccaa aagccatgac ttggttgagg
     3121 tcaaagccat attctttccc aactcggcga atgccttcta atttagaatt tccctgattg
     3181 atgacatccg atgcaaaagg attgctacgt gtcaatttca agtcttcaaa atcagctgcc
     3241 gccttctcag attcttctgg tgtcatcagc atcaaaactt ggtaaatagg ttgattcatc
     3301 aggtgaagca ggtcctcttc cttttgggga acaaccttgc tgaccatgcg attaaaagac
     3361 tgactcaccg tccgagttaa aacagaggga acgaagcgac taattcgttg ggaaaaagaa
     3421 cccagaccaa aggacatgat tttagaaccc aacatggcat ccttggtccc taaggcaatc
     3481 tccgtgccct cttttttagc atagctaatt agatggcgca aatgtaactt ggaaataggg
     3541 ctcgtgaaca agactctgtc tttactaaag atatactggc cattataggt taccgcaaaa
     3601 tccagatcca aatcgtccat caattcctta acaaaaaaag gtcctcgccc tgtcgctacg
     3661 ccaactagta ccccttgttc tttgacaatc ttaatcgcat ccttagtgga tttcaaaaca
     3721 ctcttgcgat tgttgaccaa ggttccatcg atatcaaaaa aaacagcttt gacttccatc
     3781 ctatcccaat ctcccctttt gtgatacaat gattatacca catttcagaa agagtgagta
     3841 aatcatgcct aagaaaatcc ttgttttaca tacgggtgga actatttcca tgcaggccga
     3901 tgcttctggc gctgttgtga cgagttcaga taatcccatg aaccatgtgt ccaacccact
     3961 tgaaggaatc caagtccacg ccttggactt ttttaacctt ccaagtcccc atatcaaacc
     4021 caaacatatg ctggtcctct accagaaaat taaagaggaa gcagataact acgatggagt
     4081 ggtgatcaca cacggaaccg atactttaga ggaaacagcc tatttccttg ataccatgga
     4141 agttccccat atgcctatcg ttctaacagg agccatgcgt agctccaatg aactcggtag
     4201 tgatggtgtt tataattacc taagtgcttt acgagtggcc agcgatgaca gggctgctga
     4261 caaaggagtt ttggtcgtta tgaacgatga aatccacgct gccaagtatg tcaccaaaac
     4321 acatacgact aatgtcagca ccttccagac tccaacacat ggcccccttg gtctcatcat
     4381 gaaacaggaa atcctctact tcaaaacagc tgaacctcgt gttcgctttg accttgatca
     4441 catacaaggt ttagtcccta tcatctcggc ttatgctggt atgacagatg agctgattga
     4501 tatgctggat ttagaacact tggacggttt gattatccaa gccttcggag ctggtaatat
     4561 tcccaaagaa acggctcaaa aattagaaag ccttctgcaa aaaggaattc cagtcgctct
     4621 ggtatcacga tgctttaacg gtattgccga gcctgtttat gcctaccagg gtgggggcgt
     4681 acagttgcaa aaagcaggcg ttttctttgt taaagaactc aacgcccaaa aagctcgctt
     4741 gaaactcctc atcgccctca atgccggact aacaggacag gctttgaaag actatatgga
     4801 aggctaatac tcttcgaaaa tctctgcaaa ccacgtcacg tcgccttacc gtatgtatgg
     4861 ttactgactt cgtcagtttc atctacaacc tcaaaacagt gtgttgcgca gcctttaacc
     4921 agccgcctag tccgctctat ggtattcatt aagtcaacat ctcttgttta agagcacaaa
     4981 atcaggaaat cttctcgatt ccctgatttt ttctatttac gttttcgtgt tgagctacgt
     5041 tctgtcaaac catgaggtaa gagaacttca cgttcttcca actcttcctt atgcataatc
     5101 ttggtcaaca tacgcatact aatggcacca aggtcataaa gaggttgggc aatcgttgtc
     5161 aagtttggac gggtaaagcg tgagatttgt gaatcatcac tagtaataat ttcaaaatct
     5221 tctggcacag aaacaccctt atcagccaaa ccgttcaaga ctcctgctgc caactcatca
     5281 cctgtcacaa ctgctgcagt tgcatttgat gaaatcaaac gctctgctaa ggcgtaacca
     5341 tcatcatagc tatatttaga ttcaaatacc aaaccctcac tataagtgat tcctgctttt
     5401 ttcaaggttt ccttgtagcc aactaaacga accttaccat tgatgtcatc cactagcgga
     5461 ccgctaacga aagcaatacg ctcattttct ttaacaaggt aactcactgc atcaattgtt
     5521 gcttgcttat agtcaatatt gacacttggc aactggtgct caacatcgac agttcctgcg
     5581 agaacaatcg gagtacgtga acgcgaaaat tctgagcgaa ttttatctgt caagtgataa
     5641 cccatataga taatgccatc tacctgcttt gaaaagaggg tattgacaac agaaacttct
     5701 ttctcgttat cttcatcgct attagctagg acaatattgt acttgtacat ttctgcaata
     5761 tcatcaatcc ccttagccaa actcgaaaaa taaccattgg taatatttgg aatcacgaca
     5821 ccgacagtgg ttgtcttttt acttgcaaga ccacgcgcaa ctgcatttgg acgataatcc
     5881 aaacgatcaa ttacctctag cactttttta cgggtattct cttttacatt tttattgcca
     5941 ttgaccacac ggctgaccgt cgccatggaa acacctgctt cacgagcgac atcataaatg
     6001 gttactgtat catctgcatt cattcctttt cctgtccttt ctatctcaca cattctttta
     6061 caagtagagg tgctgattga agctctatat ctacttacaa aagtgaagat gtgaaaattt
     6121 cgttttcata tttctactta ttccattcta tcactaattg taaacacttt caagtgtttt
     6181 ttgaagattg attgaaaaaa tttcatagaa aacctaggtt tagctccttg ctaccacctt
     6241 agactaaaca aaaaggagga aactaagccc tcctaaagtt atagtaaaat gaaataagaa
     6301 caggataaat cgatcaggac agtcaaatcg atttctaaca atgttttaga agtagaggtg
     6361 tactattcta gtttcaatct actataggta ttgttccatt cactaccgtc aattttagca
     6421 catagtcttc ataaaatatt atatcatcat aaccaaccag attcttttgc gatattagct
     6481 gcctctgttc gattaccagc atccagtttt gaaagaatat tggtgacata gtttcgaata
     6541 gttccgtttg agaggtaaag ctgatctgcg atttcttggt tggataagcc ccgggcgatt
     6601 ccctttaaga cagcaatctc ttgttctgtc aacggattgg gacgggtcat caccacttcc
     6661 atcaattcag gcgaatactc cttgcgtcct tcgaggacgg tgtgcaaggt ttgcatgagg
     6721 tctgcaatgc ttcgttcctt taatacataa gcatctactc cagccttgac cgcacgttca
     6781 aaataccctg ggcgcttgaa ggtcgtcact acaaccacct ttgtttcgag cttttctgct
     6841 cgtatccact ccaagacttc gagtcctgtc ttaacaggca tttctacgtc aaggatggcg
     6901 atatctacag actccttttc taatagttga attgcttctt gaccattctt ggcttgtaag
     6961 acagactcta catctgcttg aaaggcaagc aactggcaca tggcatctcg caacatactt
     7021 tgatcttctg cgactaatac tttcatctac tttctctcct tataaggtag tcgaacttgc
     7081 acttccgttg gatgtttctg actgattaca cttacttctc ctgaaaatgg agaaacacga
     7141 tctcggactg tatggagctc atctcctttt agaaaagcaa agccgcagcc atcatcactt
     7201 actgttaaaa tgagttcttt ctctgcccgt tctaatttca ggtaggcctt cgacgctttg
     7261 gcatgtttga taatattggt caccaactca agcaaaatca tggaagccgt tgactccaat
     7321 tcttgagtaa gactagcagt atctagttgg ttatccgttt ccacctcaat tccagcaatt
     7381 tctaacatct ttttcacagt ctctagttcg gatgtcaaag ttctagactt aagattttcc
     7441 acaatggttc gcacttcatt catggaatcc ttactgatct ggtgaatttc ttttaattcc
     7501 ttttccacct gtggataagc ctccatctga aataactgca aggctaaatc tgtcttgaca
     7561 ctcaacatag caaaggtatg tcccaagcta tcatgcaaat cctgaccgat acgactgcgt
     7621 tcattttcag caagcaatag atttatctgg gcattttgct tgacctgagc ttctttcaaa
     7681 tcctccacaa tacgaatccg aaccaagcca aaagtcatta aatcgacaaa agcaagaatt
     7741 acaagtagat agaatagaaa ctcaacttcg attctctgaa aaatcaacag ttggcccaca
     7801 acaaggactt gagcaagaag aaaagtccag acatgtaaag actttaaacc acctacgctg
     7861 aaatgataac ttaagagatt ggataggaaa aagaaaaacc agatataatt aacagcaaca
     7921 aaggcagtat tcccaactac ataagtcagc atgaggcccc aatatagcca agataggcgc
     7981 tggctcttag ttgttaaaac acccaaatac gccactacaa atagaatatc aatcaataaa
     8041 tgccagctag gaatctcccc agtcactaca ggtaggatgg ggaaaatcat aaaaattaaa
     8101 ctggcccaat acatatagtc tatgcttttt agtctttcaa gcattaagca ttctccttat
     8161 gaccttgaag ataaatggtc aaaccaaaca aaactgctga aaaaacaagt atataaactg
     8221 tggctgatag attgatgcca ccctcgttta agaaggtttt gagcaactcc atcaactgat
     8281 aagttggtag gcacttcccg attgcttgca tccagtctgg aaataaagag atgggcatcc
     8341 agagtccgcc taaaacagcc aagcctagat agagaagatt gcccacgaca gacatcaact
     8401 gactagaagg caagagtgtc aaggtcaagc caagcgctac aaaggcaaca cttcctacta
     8461 ttagcaagaa cgcagcccca atccagcttc ctagaggcat atccacacct cttacaaaat
     8521 gcccaactga gaaaacaacc agaattgata ccaaataatc aaccatcata cttgttatct
     8581 ttgatagata atattctacc atatttacag gggtatggcg caatgttttc tgccagttgt
     8641 tgattttatc agtatgtaag acagctggga atgaaaacat agctgtcgac atcatggaaa
     8701 aggctgtcat ggagatgagg taatcacgca taaaattcgc gagttcacct ggtgtgtcct
     8761 gatagatacc agaaaaaaat aaatagaaag ccgtcggcat ccctaccgac aatagataat
     8821 agattaattg tcgtttggtc aataaaaatt ctatcttact aagtgctatc catcgtttca
     8881 tcttagttat ctcccttttg tgtttcttca aagattgtat tcaacaaact acgattatta
     8941 acttcgattt cttgcatcct acatcctgct tgggctaata gttcccagaa agcatctgct
     9001 tctcgagtga ctacttgtag agcatcctgt ttttgtgacc agttttcaac caagttagac
     9061 tgctcaatga cttccttgta tgccagagga aggataaaat gcttttcaat tccctcacta
     9121 cgcatagcta gaggcgtcgt atcacgaatc aactctccct tatttaaaac caaaatccgg
     9181 tcagccgtat gctctacctc ttcaatataa tgagacgaat agagaatcgt gactccttgc
     9241 gcttttaggt cccgaacgat ttcccaaaag cgttgacgag ttgaagtatc catggcagca
     9301 gttggttcat ctaaaaagac aagctttggt cgcccaatca aggtcaagac aaaagagaag
     9361 agacgctttt gcccgcctga caatttttct gcgaattgct ctttttgttg ctggtcaaac
     9421 tgcaatagtt gatcgatttc ctgatcgctc aaggaatttg gatagatacg ttgaaagaaa
     9481 gcaatcaact ctttgacctt taatttctga acgatgacat tttcttgagg cagataacct
     9541 ctaatatagt ctaactgaga actcgtcact gacaagcctt ggatggatac ttgaccgctt
     9601 gtgaccagtt tatctccaag cagacagtcc aagagtgtgg tcttcccagc accattgggc
     9661 ccaatcaagg cgacgcattc accttcagct acctcaaagg aaataccctt caaaatagcc
     9721 ttgcccttga tgtttttatt taggctttct accttaatca tattcatgat attctccttt
     9781 caaccactcc attctcataa ggaaaacgac gaaaatcata aatccaaacc ccaaagcacc
     9841 acgaatgaat tggcgaagca aggtttggtc aaaccaacct gtaaacattt ccactaacca
     9901 taccaagagt gacaggccga taaagaaata gatgatccct ctcttcattc ctcaaactcc
     9961 tttttcacat ctccgactaa tttcaaacct tctctaacaa gccaagacat cattccaaag
    10021 ccagcaaaga gctcccaagg aaaatgatag aaactctcat ccaatcccga aaacatgagt
    10081 taggtcataa ctcctgctac tactaaactc actgcgataa tcattttatt tctcatctct
    10141 tcttcctcca tttcatacta caattatagt cttttgaaat cagaggagac agaagcttct
    10201 gtcactagaa aatatgacaa atgtcataaa aaattctgtt caaaacaagc aagatacact
    10261 atacaataaa acacaatcag aaaaatctaa ggcaacttcc tcaaaagaga tatcaaaccc
    10321 aattcacacc ataatgtaaa ctaatactta tttaaaatca aaaagagtag aaatttttat
    10381 cagacaaaca catatatagt gtattgaatc tataacagta gggcttaaat actaacatat
    10441 ttctataaat taatttaact ttcctgatag agctgttcat atcttatttc aattctctat
    10501 attatacgtt gaacaaaacc cttctattgc tttcttaaaa atttataaga gttataaaat
    10561 ctgttaaatt tcaatgtgta tacctaaact acggtattta ttgaaaagac tggggacaaa
    10621 aagtatacgc tgccaaaatg aattactgaa aatcaaaaaa gagagaacca aactgattcc
    10681 ctcttaatgt atataatatc tagttttaaa aatacacact cacatatctc tgt
//
LOCUS       DBEJJV010000058        10352 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.058, whole genome shotgun sequence.
ACCESSION   DBEJJV010000058 DBEJJV010000000
VERSION     DBEJJV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.058"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="ACL3GT_001933"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="ACL3GT_001933"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HGR0517537.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1319..2023
                     /gene="yycF"
                     /locus_tag="ACL3GT_001934"
     CDS             1319..2023
                     /gene="yycF"
                     /locus_tag="ACL3GT_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HGR0517538.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2016..3365
                     /gene="vicK"
                     /locus_tag="ACL3GT_001935"
     CDS             2016..3365
                     /gene="vicK"
                     /locus_tag="ACL3GT_001935"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HGR0517539.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3367..4176
                     /locus_tag="ACL3GT_001936"
     CDS             3367..4176
                     /locus_tag="ACL3GT_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HGR0517540.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4267..4509
                     /gene="relB"
                     /locus_tag="ACL3GT_001937"
     CDS             4267..4509
                     /gene="relB"
                     /locus_tag="ACL3GT_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HGR0517541.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4511..4765
                     /locus_tag="ACL3GT_001938"
     CDS             4511..4765
                     /locus_tag="ACL3GT_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HGR0517542.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4812..5555
                     /locus_tag="ACL3GT_001939"
                     /pseudo
     CDS             4812..5555
                     /locus_tag="ACL3GT_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005267 - potassium channel activity
                     [Evidence IEA];
                     GO_process: GO:0034220 - monoatomic ion transmembrane
                     transport [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(5856..6842)
                     /locus_tag="ACL3GT_001940"
     CDS             complement(5856..6842)
                     /locus_tag="ACL3GT_001940"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HGR0517543.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7036..9504
                     /gene="gyrA"
                     /locus_tag="ACL3GT_001941"
     CDS             7036..9504
                     /gene="gyrA"
                     /locus_tag="ACL3GT_001941"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HGR0517544.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9504..10247
                     /gene="srtA"
                     /locus_tag="ACL3GT_001942"
     CDS             9504..10247
                     /gene="srtA"
                     /locus_tag="ACL3GT_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HGR0517545.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         3222 a         1756 c         2305 g         3069 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat tcctggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gcctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccgg atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctttggcccc agtccagaag agagtttcca
     1021 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgcacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttg gtataatagt agagaaaaag gtgaacatat
     1321 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
     1381 gaccaaggaa ggttacgaag ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
     1441 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
     1501 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
     1561 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
     1621 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
     1681 tatgccagta gatggtcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
     1741 agaaattgtt ccagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
     1801 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
     1861 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgta cagttgatgt
     1921 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
     1981 gacgcgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
     2041 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
     2101 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
     2161 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
     2221 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
     2281 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
     2341 cgaccaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
     2401 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
     2461 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
     2521 atggcgaata tttgaacctt cgagttcgct ttgccttgat acgtcgagag tctggcttta
     2581 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgcgaac
     2641 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
     2701 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
     2761 aggtttctct tgatgagacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
     2821 cacgtattga taatgctacc agtcacctag atgtggaact gattaacttc actgctttta
     2881 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggag aaaaaatatg
     2941 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
     3001 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
     3061 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
     3121 tggggattcc taagcaggat ttaccacgta tctttgaccg tttctatcgt gtggatcgtg
     3181 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatca
     3241 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
     3301 ttgtgctccc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
     3361 actagaatga gtgaaatagg ctttaaatac agtattttag cgtcgggttc cagtggaaat
     3421 tctttttatc tggaaacctc aaaaaagaag cttttagtag atgcaggctt gtctggcaag
     3481 aaaattacca gtctgctagc tgaaattaac cgtaagccag aagacctgga tgccatcttg
     3541 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
     3601 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggc
     3661 aaggtggatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ctttggagat
     3721 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
     3781 atgaaggatg ataagagttt tgtccttttg acagatacag gttatgtcag tgaccgtatg
     3841 gcgggcattg tcgaaaatgc ggatggctat cttatcgagg ccaaccatga tgtagagatt
     3901 ttgcgatcag gttcttacgc ttggcgactc aaacaacgaa tcctatctga ccttggtcac
     3961 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
     4021 atttaccttg ggcatttatc taaggaaaat aatatcaagg aactggctca tatgaccatg
     4081 gtcaatcagc tggctcaagc tgatctggga gtcggagtag actttaaggt ttatgatacc
     4141 tcaccagata ccgcaacacc attgacagag atatagaaag aacgctgaga aggtgttctt
     4201 tttatattga ctgaacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
     4261 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
     4321 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
     4381 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
     4441 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
     4501 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
     4561 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaaggtcc
     4621 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
     4681 taattatcga gttatcgtac aaattgtaga tgatgaatta gtcgttgcta ctctagaagt
     4741 tggtcatcgg agagatattt attgaattaa agctgagtaa taacaatata gaaagtaagg
     4801 agagtaaaaa tttgaagaaa aaatggttat ttgcagatta ttatgataca acaattattt
     4861 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg actgatttgg
     4921 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
     4981 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
     5041 tattgaccat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
     5101 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
     5161 caggtaaact agaaagaaaa attagtagat tcttacgaac aaatggattg atttatatct
     5221 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     5281 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
     5341 atattgttcc agtttccctt tttgggaaat ggctagcagt tttactgatg cttgtcggta
     5401 ttggaacaat agggatgcta acaagtgctt tgacgaactt ttttgtaaag gataatccag
     5461 atgaacagat aaaacttgat aaactcaaag acgaattatc gagctaaaga atattaatag
     5521 agaaacaatc tgaaaaaatc gaagaactac attgaatgat aaaagactta gttgaaaaaa
     5581 tatcataaag gtgagacaaa ataaaacttg attcgaggag aaatcaagta agttttgaca
     5641 caatagaacg catattatca ggtataaaaa cttgatacta tgcgttttat agagaaataa
     5701 aataaaatct gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagta
     5761 atggggtgct atttcaactt caacctacta taatacagaa aaaaatacag aaaaaaacaa
     5821 ctccctgatg attcaaggag ttgtctatag ttaaattagt ttttagaagc ttcttggaat
     5881 tctggatttt tccatgcttc gtcaataata gcttgcaatt ctttagcaga tgcttgcatt
     5941 ttttgagttt ctgcatcgtt caatggaatg tttactggac gaacgatacc atgtgcacca
     6001 acaacagctg gttgaccgat aaagacattc tcaactccgt attgaccttc ttggaatact
     6061 gaaagtggaa gtactgcgtt ttcatcgtca aggattgctt tagtgatacg agcaagggct
     6121 actgcgatac cgtagtatgt tgcacctttt ttgttgatga ttgtgtaggc tgcatcacga
     6181 acaccttcga acaattcaat caattcagct tcttgaacat tttgagtgtc tttaaggaat
     6241 tcttcaaggt ttacaccagc gatgttagcg tgtgaccaaa cagcgaactc agagtcaccg
     6301 tgttcaccca tgatgtaggc gtgcactgaa cgagcatcca catccaattt ttcagcaagt
     6361 gcttgacgga aacgagctga gtcaagtgaa gtacctgaac cgataacgcg ttctttaggg
     6421 aaaccagaga atttccaagt tgagtaagtc aaaacgtcaa ctgggttagc agcaacaagg
     6481 aagatacctt tgaaaccaga ttcaacaact tgagttacga ttgatttgtt gatagcaagg
     6541 tttttaccta caaggtcaag acgagtttca cctggttttt gaggtgcacc tgcagtgatc
     6601 acaacaaggt cagcgtctgc acagtcagag tattgagctg catagatttt tttaggtgaa
     6661 gtgaaggcaa gggcgtgact aaggtcaagc gcatcaccaa cagctttttc atgcaattgt
     6721 ggaatttcga taattccaag ctcttgtgca attccttggt taacaagtgc aaaagcgtaa
     6781 gatgaaccta cagcaccatc accgacaagg ataacttttt tgtgttgttt agttgaagtc
     6841 attgttttaa acatctcctt aattttatta ggggattttc cctagacaac ttcattctat
     6901 cacttttaaa aaactttgtc acgaatatgc cttatagttc tcgatgtaaa cgttttagtg
     6961 gtttagaggc tgaaatagat gggaatttat ggtataatgt tgttacttac taattgtgaa
     7021 atgaggcatt tattaatgca ggataaaaat ttagtgaatg tcaatctgac aaaggagatg
     7081 aaggcaagtt ttatcgacta cgccatgagt gttatcgtag cgcgagctct tcctgatgtt
     7141 cgagatggct taaaacctgt tcaccgtcgc attctctacg gaatgaatga attgggtgtg
     7201 accccagaca aaccccataa aaaatctgct cgtattacag gggatgtcat gggtaaatat
     7261 cacccacacg gggattcctc tatttatgaa gccatggtcc gtatggctca atggtggagc
     7321 taccgttaca tgcttgtaga tggtcatggg aattttggtt ccatggatgg agatagtgct
     7381 gccgctcaac gttataccga ggcacgtatg agcaagattg ctctggaaat gcttcgtgat
     7441 atcaacaaaa atacagttga tttcgttgat aactatgatg ccaatgaacg ggaacccttg
     7501 gtcttgccag cgcgttttcc aaaccttttg gttaatggag caactggtat cgcggttggg
     7561 atggcaacca atattccacc tcataatctg ggtgaaacca ttgatgcagt gaagttggtc
     7621 atggataatc ctgaagtgac taccaaggac ttgatggaag tcttgcctgg accagatttt
     7681 ccaactggtg ctcttgtcat ggggaaatca ggtatccata aggcttatga aacaggtaaa
     7741 ggttcgattg tcctacgttc tcgtacagag attgaaacga ctaagactgg tcgtgagcgt
     7801 atcgttgtaa cagaatttcc ttacatggtc aataaaacca aggtgcatga gcatattgtt
     7861 cgcttggttc aggaaaaacg cattgagggt atcacagcag tacgtgatga gtcaaaccgt
     7921 gaaggtgttc gatttgttat tgaagtcaag cgcgacgcct cagccaatgt tattctcaat
     7981 aacctcttca aaatgaccca aatgcaaacc aattttggat tcaatatgct cgctatccaa
     8041 aatggtatac cgaaaatttt gtctcttcgt cagattttgg atgcttatat tgagcaccaa
     8101 aaagaagtgg ttgttcgtcg tacacgtttt gataaggaaa aagcggaagc gcgcgctcat
     8161 atcttagaag gtctcttgat tgcgctagac catatcgacg aagtgattcg tatcatccgt
     8221 gctagtgaaa cggatgcgga agctcaagct gagttgatga gcaagtttaa gctttctgaa
     8281 cgtcaaagtc aagctatcct tgatatgcgt cttcgtcgtt tgacaggttt ggaacgcgat
     8341 aagattcaat ctgagtatga tgacctcttg gctctgattg cggatttagc agatattctt
     8401 gctaagcctg aacgtgtttc tcaaattatc aaagacgaat tggatgaagt taaacgtaaa
     8461 ttttctgata aacgccgtac agagttgatg gttggacaga tcttgagtct cgaggatgag
     8521 gacttgattg aagaatcgga tgtcttgatt accctttcta acagaggcta cattaagcgt
     8581 ttggatcagg acgagttcac tgctcaaaaa cgtgggggtc gtggtgtcca aggaacggga
     8641 gtgaaagatg atgactttgt tcgtgagtta gtgtcaacta gcacccatga tcatctgctc
     8701 ttcttcacaa acaagggacg tgtctatcgt cttaaaggtt atgaaattcc tgagtatggt
     8761 cggactgcca aagggctacc agtagtcaat ctcttgaaat tggatgaaga tgaaagtatt
     8821 cagacggtta tcaatgttga gtctgatcgc agtgatgatg cttatctctt ctttacaacc
     8881 cgtcacggta ttgtgaagag aactagtgtt aaggagtttg ccaatattcg tcaaaatggt
     8941 ctcaaagcgc tgaatttaaa ggatgaagat gagttaatca atgtcttgtt gacagaagga
     9001 gatatggata ttatcattgg taccaagttt ggttatgcag ttcgctttaa tcaatcagcc
     9061 gttcgtggta tgagccgtat cgccactggt gtgaaaggtg ttaaccttcg tgaaggagac
     9121 acagttgttg gtgccagctt gattactgat caagatgagg ttcttattat cacagaaaaa
     9181 ggatatggta agcgtacagt cgctactgaa tacccaacaa aaggtcgtgg tggtaaggga
     9241 atgcagacag ctaaaattac cgaaaaaaat ggcttgctgg ccggtcttat gactgttcaa
     9301 ggggatgagg atttgatgat tatcactgat acaggtgtca tgattcgaac caatcttgcc
     9361 aatatttcac aaacaggacg tgcaactatg ggagttaaag taatgcgcct ggatcaagat
     9421 gctcagatag tgactttcac aacggttgcg gtggcagaaa aagaagaagt tgggacagaa
     9481 aacgaaacag aaggtgaagc ataatgtctc aaaaaaataa taaaaagaaa aacaagcgaa
     9541 aaaatctgct gacaaatatc ctagcaggat ttctgatatt actgtcactg gctttgattt
     9601 ttaatactca aattcgaaat attttcatag tctggaatac caataagtat caagttagcc
     9661 aggtatcaaa agaaaaatta gaagaaaatc aggatacaga aggcaatttt gactttgatt
     9721 ctgtcaaagc tatctcttcg gaagctgttc taacttctca atgggatgct caaaaattac
     9781 cagttattgg gggaattgca attcctgaat tggaaatgaa tttgccgatt tttaaaggac
     9841 ttgataatgt taatctcttc tacggagctg gtacaatgaa acgcgagcaa gtaatgggag
     9901 aaggaaatta tagtctagct agtcaccata tctttggtgt tgataatgct aataaaatgt
     9961 tattttctcc tttagataat gctaaaaatg gcatgaagat ttatctaacc gataaaaata
    10021 aagtttatac ttatgaaata cgtgaagtca aacgtgtgac accggatcgt gttgatgaag
    10081 ttgatgatag agatggggtc aatgaaatca cattagtaac ctgtgaagac cttgctgcta
    10141 cagaacgtat tattgtcaaa ggtgatttga aagaaacaaa agattattca caaacatctg
    10201 atgaaattct aacagctttc aatcaaccat ataaacaatt ttattaatac aaatcagtga
    10261 aatcatggat ttcactgatt ttttaagatt ttcataaaaa tatagtaaaa tgaaataaga
    10321 ataggacgaa tcgttcagga cagtcaaatc ga
//
LOCUS       DBEJJV010000059        10239 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.059, whole genome shotgun sequence.
ACCESSION   DBEJJV010000059 DBEJJV010000000
VERSION     DBEJJV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10239
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.059"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            83..757
                     /locus_tag="ACL3GT_001943"
     CDS             83..757
                     /locus_tag="ACL3GT_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HGR0517546.1"
                     /translation="MDSNFAGRLNILRAGVLDANDGIISIAGVVIGVASATTNIWIIF
                     LSGFTAILAGAFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQN
                     GEFKTSAQLLTNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPML
                     SVTIFPSDYRIPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLL
                     EQLFSI"
     gene            complement(799..2787)
                     /locus_tag="ACL3GT_001944"
     CDS             complement(799..2787)
                     /locus_tag="ACL3GT_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0517547.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFTKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2789..3547)
                     /locus_tag="ACL3GT_001945"
     CDS             complement(2789..3547)
                     /locus_tag="ACL3GT_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HGR0517548.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3975..4166
                     /locus_tag="ACL3GT_001946"
     CDS             3975..4166
                     /locus_tag="ACL3GT_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517549.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4520..4792)
                     /locus_tag="ACL3GT_001947"
     CDS             complement(4520..4792)
                     /locus_tag="ACL3GT_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HGR0517550.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4851..5300)
                     /locus_tag="ACL3GT_001948"
     CDS             complement(4851..5300)
                     /locus_tag="ACL3GT_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HGR0517551.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            complement(5287..7416)
                     /locus_tag="ACL3GT_001949"
     CDS             complement(5287..7416)
                     /locus_tag="ACL3GT_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HGR0517552.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            7532..7672
                     /locus_tag="ACL3GT_001950"
     CDS             7532..7672
                     /locus_tag="ACL3GT_001950"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517553.1"
                     /translation="MDRTDEVSSKHCFEVVDRTDEVSSKHCFEVVDRTDEVSNRTTVR
                     RS"
     gene            7786..7917
                     /locus_tag="ACL3GT_001951"
     CDS             7786..7917
                     /locus_tag="ACL3GT_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HGR0517554.1"
                     /translation="MAVKFTKRDDLDKMFEEFAKLPDLKQVTFPDDKEKKVKAEKKN"
     gene            7918..8823
                     /locus_tag="ACL3GT_001952"
     CDS             7918..8823
                     /locus_tag="ACL3GT_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HGR0517555.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            8820..9635
                     /locus_tag="ACL3GT_001953"
     CDS             8820..9635
                     /locus_tag="ACL3GT_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HGR0517556.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTNLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(9765..>10239)
                     /locus_tag="ACL3GT_001954"
     CDS             complement(9765..>10239)
                     /locus_tag="ACL3GT_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HGR0517557.1"
                     /translation="LILLDGGYLDLDKILPLDTELEETKNYIKSQIISDLDVLTSKEK
                     SEAKHWSENMEKAVRQSYHWNVEYNRYELAINYENIEAILRLRRKIQAFKREVGDTLF
                     ISPRYPNEATWREEALKELPDYFDTIFLENFGHELYTQAPKEIASLMNEWLAYFL"
BASE COUNT         3017 a         2151 c         1965 g         3106 t
ORIGIN      
        1 tgcttggact acaagtcacc cagagaagac ttctggatgg ctaacttgaa cttgaaattt
       61 agcgtcagaa acaaatcacg aaattgattc aaattttgca ggtcgtttaa atatcctgcg
      121 tgcgggtgtt cttgatgcta acgatggaat tatttccatt gctggtgtgg ttatcggagt
      181 tgccagtgcc acgaccaata tctggattat ctttttatca ggttttacgg ctatcttagc
      241 tggtgccttt tcaatggctg gtggagaata tgtatccgtt tcaactccaa aagataccga
      301 ggaagctgcc gtttcgcgag aaaaactctt gctagaccaa gatagggaac tagccaaaaa
      361 atccctctat gctgcttata tccaaaatgg agaattcaaa acttctgccc aactcttgac
      421 caataagatc tttcttaaaa atccactcaa ggctctggta gaggaaaaat atgggattga
      481 gtatgaagaa tttaccaatc cttggcacgc tgccatttct agcttcgttg cctttttcct
      541 tagaagtttg cctccaatgc tgtcagtgac catttttcca agtgattacc gcatccctgc
      601 taccgtcctt attgtcggtg tggcccttct tctcactggt tacacaagtg ctagacttgg
      661 aaaagcccca accaaaacag ctatgattcg gaaccttgct attggtctct tgaccatggg
      721 agttaccttc ctgctcgaac aacttttcag catttagaat acaagaaata cctcgatttt
      781 gaagtcgagg tatctttttt acatttgcac aatcttgcga taacttcttg aagtaatcat
      841 gaaaatcagc acataggcga tgaggaagat agcgcagata gacaaggtca caatcaacat
      901 catagtcgta tccagtacac caatcacttt taaaatcagg ctaagcatat ggtaggcaaa
      961 ggcgagatgt atgaaggcaa agagcaaagg aaggaagaaa acagttaaaa cctgtttgtt
     1021 gatggtttgc ttgatttgct tttggtccaa accgactttc tgcaagataa taaagcgttc
     1081 acggtcttcg tagccttcag aaatttgttt gtagtagatg accagaacag ttccgaccat
     1141 aaagataatg gataggaaaa taccgataaa gaagacacca ccaaagaggg cactcatctg
     1201 agaactagca tctgctagat tgctaccata aacatagcta ccttctgtgt ctaattgagc
     1261 attaaattga ttgaggtagt tttcatactc ctcagcgacc ttgagttgtt cttcttcgct
     1321 ggcatctaca ttcataccac cgtaaaactg attatagata gccgaatctg ggaattgatc
     1381 caaaaaggct tgtaaatcag gaacaacaag gtaattgtaa tcagtagtca agatattaaa
     1441 cttatttgga acatggttga caataaaatc tttagtaaat tcttctttga cagaaaattg
     1501 atgatcattt agagttagag ctttctgtcc tttcagtccg tcatttttgg caaagagacc
     1561 gacctcattt cctgatagag acagtttttg accagtcata ttttcataat ctttttggtc
     1621 aaataccatg aaaactgttt ttggttggac acggttttgt cctttttcaa aaatagttaa
     1681 cttggttcct tcttgattcg caacagcaaa gtaagtgtaa cgaaatactt ctttttcttt
     1741 aatcttataa cctttgtcac ttgcaaactg gctcaagagt ttgtccaagt cttctttttc
     1801 aacattttgc cctgaaaccc caaaatcatg aggatttaga acttttttaa agctttctga
     1861 ggaattgaaa atgcttgtcg ctgctgacat ggttaccaaa accattgttg acaagatagc
     1921 gatggtggct agtccaactg catttttctt catacggaaa atcaagttag aaacagatat
     1981 gaggttattt ggttggtaat agtatttctt atttttcttt aagatttgga ggaaaacggt
     2041 aatccctgca ttaaacaaga gataagtccc aaagataacc agtaaaacag ctatgaagaa
     2101 ggttgttaag gctgtaagag gatcttttac cgtaagggca agataatagc caattcctaa
     2161 acttatggaa ccaagaatgg tttggagagg aaggaagcga ccttttttct ctccactagc
     2221 tttctcacga gagagctgga gggcattcat acgggcgatt cgaagggcat tcaggaacat
     2281 gaggcctagg aaaatcaaac cgaagacaac aagcactgta atgacaactt tcgtctggaa
     2341 ggtagcaacc agctcaacct tcaatttcat tagtttgagc aggaaagcga aaattaactt
     2401 gtcaaacaag gctccaatac cgatacccgc tccaacagtt agaatcccaa ataccactaa
     2461 ctccttaaag gtcatactga taagatgacg cttctccaag cccaacatgc cataaattcc
     2521 tagttccttg gaacggttct tcatgacaaa actattggca tagagaacga taatggctga
     2581 cgcaagggtg acgacaaaca taccaaatcc aagtgtagcc tgaatggttg ttcctccacg
     2641 gatttccgca atcttaggat tgaaggttag agagtaaaag agataggtga cagtgactgc
     2701 caagagaaca gccagcgcaa aaggatagta gagtttgcgg tttttaatca agttcgatac
     2761 cgctaactta ttggttaatc gaaacatact aattcacctc gcttgccatg acagtcaagg
     2821 tatcagagat ttcttggaac atctgacgtt ctgtcttctc tccacggtag atttgattgt
     2881 aaagaatgcc gtctttgata aagagtacac gtttagctct gctagctgct gctgttgagt
     2941 gggttaccat gagaatggtt tggccgcgct cattgatttc atcaaagaca tcaagtaagg
     3001 ctgcagatga cttggagtca agagctcctg tcggttcgtc cgcaaggaga atttcaggtt
     3061 ctgtgatgat ggcgcgggct actgctacac gctgtttctg accaccagaa atctcgtaag
     3121 ggtacttctc ttgtaattgg tttattccca gattctcagc tgtcaccacc aatttcttca
     3181 tcatctctgt aataggtctt cttgacaaga caagcggaag caagatattg tcctttacag
     3241 atagagtatc tagcaagtta aagtcttgga agacaaagcc caacttttca cgacggaagc
     3301 tagaggcctg tgaattttta atggttgcgg tgtcagttcc attcaagtaa acctgaccac
     3361 gacttggttt atccagcata gctagaatat tgagaagagt tgatttacca gaaccagact
     3421 cacccatgat ggcaacgtag tcaccctttt cgacggtaaa gtgaatatcc ttgagggctt
     3481 ctacttggtt gccctgaaaa cgtgttttat aaattttttg aacgtgtttt acatctaaaa
     3541 gtgtcatgag aatctccttt cttaatatcc catcaaatga aatgtagctt gcatcatagt
     3601 gcatcccagc tgaacgcgct caatttcttt gtgacttggt tttctagttt tcttatgtaa
     3661 gatttgtttc atgatgttac tcctttgttc tttatgagtc tagtttacat caaaaaaaga
     3721 ccgcttgcca taacctaacc ttacaaaaga gactttaatc ttacattttt gtaagattgg
     3781 gtgaaatata agcaaaatta cttagaaaat gatttgattt cctattttta aagttgtaaa
     3841 atataagtgt gaaaaggctt actttgaaaa ggaggaagcg ggaactaaca ttttagtaag
     3901 gttacctaga taacatacca ttcaatttaa cacttgcaag tcgttcaacc tataaggaaa
     3961 gaaggtgcgc tttaatgaaa cacaaagaac atatactcat cggacttctc tatctgctct
     4021 ctccattcat cggtcagctc ttagttgaac acacacactt tatcggtaca gaatttaccg
     4081 gcactgctta tgttatttgc tggttatcag ttgttatcag catccaccat ttttccaaaa
     4141 atgtattgtc tcagcagcaa aaatagatta aaaaactgag tttaaattac tgcttttata
     4201 ataaaatgaa ataagaacag gacaaatcga tcaggatagt caaatcgatt tctaacaatg
     4261 ttttagaagt agaggtgtcc tattctagtt ccaatccact atagtttgtg gatgaagctg
     4321 gcgaaatatt attaatacta ttcaaaaatc aaagtgcaaa ctatgtcaac ttcacattgc
     4381 cgactaaatt acagcctgtg gctggcttcc tagtttgcac tttgattttt attgagtata
     4441 aaagtaaaaa agctttaaat caagcagttt agactattga tttaaagctt tttgcttatt
     4501 ccaaatcttc tgtagaacct caccaaaacc agccttcatt gtcgtcaatg gcttgggctt
     4561 ctttgcgttt acgtgggcct gttccgtaca tttctgcttc gatttcttcc ttggtaggca
     4621 tgatagaagc taggatgata tagataatca cgccaagtcc aaagtttgca actgtaaaaa
     4681 tagcaaacaa gaaacgaact agggtaacat caaaattcca cttgtctgac agacctgcca
     4741 gaactcctga aatcatgcga ttgcgtctca ttttataaaa tttactgttc atgatatttc
     4801 ctctttctgc taggttagac atagtatatc acggggaggc tcggctttca tcagtcctca
     4861 ggctgattta tcagaagcaa tttacctcga caaagtccac agcgatagcg tttggtatca
     4921 atcctacgct tgcgctgata cctttgctgg caggattgac aacgataaag cttgagtggt
     4981 ttagagttac tattgggcaa ggatggtaca aaccgtaatc catccactgc tttcaaaagt
     5041 tccttaaaat cccgatcctt gtgttgatag cccttccctt ggaaataaag gtgataatga
     5101 cagagttcat gtcggacaat tttcctaaaa acctccatac ccagtttctg ataaaccttg
     5161 ggattaaaat ccagatgccc atctttgggg aaaaatcgcc cacctgtcga acgtagacgc
     5221 ctattccact ggacatgatg gataaaagct ctcccgaagt cttctagtga aacctgcttg
     5281 acataatcag tcagtttcat ttggagcgag gagcgacaga ttaacttttt cacgttcagt
     5341 atcaattttc ttgacccaaa cggtcaccaa atctccaact gccaccactt gactagggtg
     5401 tttgataaac ttgcgactca tatgagaaat atgaatcaag ccgtcctcgt gaatcccgat
     5461 atcaacgaag gcaccgaagt caacaacgtt acgcacaaca ccttctagct tctgacctac
     5521 cactaggtct ttgatatcta ggacatcttg gcgaagcaca ggtgcgtcaa aggaatcacg
     5581 gaaatctcga cctggtttga gaagatctgc aatgatatct ttaagggttt ctggaccgag
     5641 gtctagctct tgagccattt ccttgactga aagcgacttg agtttgcttt gggcctcttc
     5701 attcagatcc ttaatgtcca agcatttgaa gagttcctta acggcagcgt aattttctgg
     5761 gtgaactcct gtattatcaa ggatattgct actttcaggg atacggagga aaccagcagc
     5821 ctgttcaaaa gccttggccc ccaaacgagg aactttcttg atttgggagc gtgaagtgat
     5881 ttttccctct tcctcacggt atttgacgat attttcagaa atggttttat tgagtccagc
     5941 tacgtgtgaa agaagagctg ggctagctgt attgacattg acaccaactt ggttaaccac
     6001 tgtatcgaca acaaagtcca gactctcaga tagtttcttc tgactgacat cgtgttggta
     6061 ttgaccgaca ccaattgact taggatcgat tttgaccaat tccgcaagag gatcttgcaa
     6121 acgacgggcg atagaaatgg cagagcgttt ttcaacggtc aagtctggaa actcctgacg
     6181 agcaagttcg ctggcagaat agacagaagc accactttca ttaacgataa catagctgac
     6241 ttcagggaaa tctttcagaa cttccgctac aaaagcttca ctttcacgac tggccgttcc
     6301 atttccaatg gcaataatct ctacaccgta ttgaccaatt aaatctgcta aatctttctt
     6361 ggcttcttcg atttgacgag ctgatgctgg tttaacagga taaataacct gagttgtcag
     6421 catttttcct gttgcatcca cgacagctag cttggcacct gtacgaaagg ctgggtcaaa
     6481 cccaagaacc acgcgccctt tcagtggagc aaccaagagg agattgcgca gattgtcaga
     6541 aaaaagttgg atagctccct cttcagcttt ctcagttaat tctgtccgaa tacgacgctc
     6601 aatagcaggc aagacctttt tcttaacgga ttgctgaaca acttcatcaa tataagcatt
     6661 tttcaccttg aaacgagtag caaagaaggc aagaatacgg tccgtcgcat gttcaaaacc
     6721 gatcttcaag acaccaagtt tctccccacg attgagagcc aaggtacgat agccttgcat
     6781 agttccaact gtctctgaaa aatcataata aatctgaaaa acctgctttt catcaagact
     6841 ttcatccttg gcttgagaag tgagtttaga gtgtctcagc acttcctgat aagtcataga
     6901 acgcaaggtc acatcttccg ataaggcttc gaccaaaata tcaactgcac cggtcaaggc
     6961 ttccttgcca gtcgcaaatc cttcacagac gaacttttca gcttctttct ctaagtcaac
     7021 tatattctgc aaaatcaaac gagcaagagg aaagagtcca gcttcacggg caatggttgc
     7081 cttggtacga cgcttttcct tataaggaag atagagttct tcaacgtctg ctaatttttc
     7141 ggcaactaag atagcttctt ccaattcctt ggtcaactta ccttgttctt gaatcttagc
     7201 taagacagct tccttacggt cattgagatt tgtcagactt ttatccaaat caataatagc
     7261 cttaatcgcc acctcatcca gactaccagt catgtccttg cgataacgcg cgataaaggg
     7321 aatagtcgcc ccttcagctg tcaaacttag aacggtatca atttgcttta acgtcactcc
     7381 caaatcctga gagatttttt catatttttt atccataaat ctattatacc acaagctgga
     7441 aggctttctc caatcctttt catactcaat aaaaatcaaa aagcaaacta ggaagctagc
     7501 cgtaggctgc tcaaaatact gttttgaggt tgtggataga actgacgaag tcagctcaaa
     7561 acactgtttt gaggttgtgg atagaactga cgaagtcagc tcaaaacact gttttgaggt
     7621 tgtggataga actgacgaag tcagtaaccg tactacggta aggcgaagct gacgtggttt
     7681 gaagagattt tcgaagagta tcaactatcg aaaacaaatt aaaaaactcc cttttccgca
     7741 aaataatagt ataatagagg tagaatttag aatcgaggta cacctatggc tgtcaaattt
     7801 acaaaacgag acgacttgga caagatgttt gaagagtttg ctaaactccc tgatttgaaa
     7861 caagttactt tccctgatga caaagagaaa aaagtcaaag cagaaaagaa aaactagatg
     7921 actgcttttc aacaactccc atctagtgta cttcaaactg gagccatttt tctctccatt
     7981 atcattgaag cccttccctt cgttctgata ggaagcattg tctcagggct gattgaagtt
     8041 tatatcacac ctgacaaggt ttatcatttt ctccctcgaa atcgttgggg gagaatcttt
     8101 tttgggacct ttgtcggtat acttttccct tcttgtgaat gtggaatcgt ccccatcatc
     8161 aatcgttttc tggaaaaaaa ggttccaagt tacacggccg ttccttttct tgtgacagca
     8221 cctgttatca atcccattgt tctttttgcg acctattctg cctttggcaa ctccttccat
     8281 gtcgccctat tacgagctct gggttccatt cttgtggctg taatactagg aatttttcta
     8341 ggatttttct ggcaagaacc gattcagaaa gaaaatcgtc tggcttgtca tgagcatgat
     8401 ttttcttact tgagttctgc aaaaaaagtt tttcaagtct ttgtgcaggc cattgatgaa
     8461 ttttttgata cggggcgtta tttggtattt ggctgcctct ttgcttctat aatacaggtc
     8521 tacgttccga ctcggattct gacctctatc agtgcgaccc ctctttttgc catcctgctc
     8581 ttgatgattt tagcctttct tctttcgctc tgtagtgagg cggatgcctt tataggtgct
     8641 tctcttctct cgagtttcgg tttggcacca gttctggcct ttctcgtcat tggtccaatg
     8701 ctggatatca aaaatattct catgatgaaa aattacttga aagcacgatt tatcagtcac
     8761 ttcataacaa ttgtaactct tgtcgtctta gtctattctc tcttgattgg agtcatccta
     8821 tgattcgatt tttagtttta gctggctatt ttgaactgac tatttacctc catctgtcgg
     8881 gcaaactaaa ccagtacatc aacatgcact attcctatct ggcctatatc tccatggtgc
     8941 tttcttttat cttggctatc gttcaattgt atatctggat gaagcaagtc aaaacccaca
     9001 gtcatctgaa cagccgattg gccaagatga cgagtatttc tcttctggct attccacttg
     9061 tcatcggctt aactttccca actgttagct tggattctca gactgtttca gctaaaggct
     9121 atcatttccc tctatcggaa ggaacgaatc tggctattca gacaagtgaa gggactacaa
     9181 gccaatattt gaaaccagat actagttctt atttttcaaa atcagcctat gaaaaggaaa
     9241 tgcgaacggc ggcggataaa tacttatccc aagacagcat tcagatcact aatgaaaact
     9301 atatggaagt catggaggct atctacgact atccagatga gtttgagggc aagacaatcc
     9361 agtttacagg ctttgtctat aacgacccca gtcatgccaa tagtcaattt ctgttccgat
     9421 tcggcattat ccactgtatc gcagattctg gtgtctatgg attgctgacc aagggcaata
     9481 cccggcagta tgaaaacaac acttggattt cagccaaagg aaaactggtc aatcactacc
     9541 ataaagaact caaacaaaac cttccaacct tggaaatcga cagctttacc aaagtcgata
     9601 aaccagaaaa tccctatgta tatagagctt tttaagaaaa tcaagataaa aacgaacaag
     9661 ttctcttctg aataacagaa aaagagcctg ttcgtttttt ggttatatga aaattagtga
     9721 cttgtaaatt ttcatcttat accatttcca gcaatacaag tagctcatag aaaataagcg
     9781 agccactcat tcattagact agcgatttct ttaggtgctt gagtataaag ctcatggcca
     9841 aagttttcta aaaaaatagt atcaaaatag tctggcaatt cttttagggc ttcctctctc
     9901 catgtagctt cattaggata gcgaggacta ataaacaagg tatctcccac ttctctctta
     9961 aaagcttgta tttttctccg taggcggagt atcgcttcta tattttcata atttatagcc
    10021 aactcatatc tattatactc aacattccag tgataggact gtcttacagc tttctccata
    10081 ttttctgacc aatgctttgc ttcagatttt tctttagaag taagaacatc taagtccgaa
    10141 ataatttgag atttgatata atttttagtt tcctctaact ctgtatccaa aggtaaaatc
    10201 ttatctaaat ctagatagcc accatccaaa agaatcagt
//
LOCUS       DBEJJV010000060        10230 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.060, whole genome shotgun sequence.
ACCESSION   DBEJJV010000060 DBEJJV010000000
VERSION     DBEJJV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 10230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10230
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.060"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..223
                     /locus_tag="ACL3GT_001955"
                     /pseudo
     CDS             1..223
                     /locus_tag="ACL3GT_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            309..521
                     /locus_tag="ACL3GT_001956"
                     /pseudo
     CDS             309..521
                     /locus_tag="ACL3GT_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            421..867
                     /locus_tag="ACL3GT_001957"
     CDS             421..867
                     /locus_tag="ACL3GT_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HGR0517558.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1005..2309)
                     /gene="eno"
                     /locus_tag="ACL3GT_001958"
     CDS             complement(1005..2309)
                     /gene="eno"
                     /locus_tag="ACL3GT_001958"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-displayed alpha-enolase"
                     /protein_id="HGR0517559.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2473..2919
                     /locus_tag="ACL3GT_001959"
     CDS             2473..2919
                     /locus_tag="ACL3GT_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HGR0517560.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAKPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2916..3719)
                     /locus_tag="ACL3GT_001960"
     CDS             complement(2916..3719)
                     /locus_tag="ACL3GT_001960"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0031388 - organic acid phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HGR0517561.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLCAFAQASIVSGID
                     TCLDLINFDKKVSDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAED
                     LPPLPFENIQAVFSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3728..4057)
                     /locus_tag="ACL3GT_001961"
     CDS             complement(3728..4057)
                     /locus_tag="ACL3GT_001961"
                     /inference="COORDINATES: protein motif:HMM:NF019887.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HGR0517562.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4002..4373)
                     /locus_tag="ACL3GT_001962"
     CDS             complement(4002..4373)
                     /locus_tag="ACL3GT_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HGR0517563.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4432..5865)
                     /gene="glgA"
                     /locus_tag="ACL3GT_001963"
     CDS             complement(4432..5865)
                     /gene="glgA"
                     /locus_tag="ACL3GT_001963"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HGR0517564.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYCWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(5862..7001)
                     /gene="glgD"
                     /locus_tag="ACL3GT_001964"
     CDS             complement(5862..7001)
                     /gene="glgD"
                     /locus_tag="ACL3GT_001964"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HGR0517565.1"
                     /translation="MKIDKYSAILGNTVGFHDMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVELGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(6991..8133)
                     /locus_tag="ACL3GT_001965"
     CDS             complement(6991..8133)
                     /locus_tag="ACL3GT_001965"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HGR0517566.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8123..10051)
                     /gene="glgB"
                     /locus_tag="ACL3GT_001966"
     CDS             complement(8123..10051)
                     /gene="glgB"
                     /locus_tag="ACL3GT_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA];
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_function: GO:0043169 - cation binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HGR0517567.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELREKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3115 a         2254 c         1800 g         3061 t
ORIGIN      
        1 gaaccacacc tactatgaac aagacccaga aaaagtagcc ttatttctta agaattttaa
       61 tagtttaaag cacctagcac aggtctaaca aatgaatggt gagttaatcg ctccaatgac
      121 ttacgaagag acgatgacga gcgacttttt tgaagcttgg tttcagaaat ttctcttacc
      181 aacattaacc gcaccattgg ttattatatt aaaacgaagt aagaatagga caaatcgatc
      241 aggacagtaa aatctaattc taacaatgtt ttagaagtag aggtgtacta ttctagtttc
      301 aatctactat attaatggac aatgcaagat tccatagaat ggggaagcta gaactcttgt
      361 gtgaagagtt tgggcataaa cttttacctc ttcctcccta ctcgcctgag tacaatctta
      421 ttgagaaaac atgggctcat atcaaaaagc acctcaaaag ggtattacca agttgcaata
      481 ccttttatga ggctcttttg tcttgttctt gtttcaattg actatataaa ttgtctaagc
      541 gaaacaaccg ataagaattg gcacaaaagc gaccgtattt ttgttaccaa tacaggaaaa
      601 ccagttcata gttctatctt gagcaagtct ctccagcgag caaacgaacg ccttaaaaaa
      661 ccaattccca aacatctgtc ccctcacatc ttcagacaca ccactattag catcttatca
      721 gaaaataaaa ttcctttaaa aacaatcacg gacagggttg gtcattccga ctctgaagtc
      781 actacttcca tctacaccca cgtcacaaag aacatgaaag atgaagcaat caatgtactg
      841 gataaagtta tgaaaaagat tttttaaaaa gttttgtccc ttttttgtcc tctaaataca
      901 aaaatagccc ttcggataaa atccgagggg ctagaaacgt tgttaaatca acggccgaac
      961 ttttgaattt catggttcgg gataaaatag ttcactgaac tattttattt tttaaggttg
     1021 tagaatgatt tcaatccacg atattcagct acttcaccaa gttggtcttc gatacgaagc
     1081 aattggttgt atttagcgat gcggtctgta cgtgaaagtg aaccagtctt gatttgtcct
     1141 gcgttagttg caactgcaat atcagcgatt gttgaatctt cagtttcacc tgaacggtgt
     1201 gatacaacag cagtgtaacc agcttcttta gccatttcga tagcttcaaa agtttcagta
     1261 agagtaccga tttggttaac tttgataagg attgagttag cagcaccttc ttggatacca
     1321 cgtgcaaggt agtcagtgtt tgttacgaag aagtcgtcac caacaagttg tactttctta
     1381 ccaagacgtt cagtaagagc tttccaacca tcccagtcgt tttcatccat accatcttca
     1441 atagtgatga ttgggtattt gttaaccaat tcttcaaggt agtcgatttg ttctgcagat
     1501 gtacgaacag cagcaccttc accttcaaat ttagtgtagt cgtaaacttt acgttcttta
     1561 tcgtagaatt ctgatgaagc acagtcaaat ccgataaata cgtctttacc tggtacatat
     1621 ccagcagctt caatcgcagc aaggatagtt tcaacaccat cttcagttcc ttcgaaacga
     1681 ggagcgaatc caccttcgtc acctacggca gtttccaaac cacgtgattt aaggattttc
     1741 ttaagagcgt ggaagatttc agcaccgtaa cgaagggctt ctttaaatgt tggcgcacca
     1801 actggcaaga tcatgaactc ttggaaagcg attggagcgt cagagtgaga accaccgttg
     1861 atgatgttca tcattggagt tggaagaact ttagtgttga atccaccaag gtagctgtaa
     1921 agtgggattt caaggtagtc agcagcagca cgagctacag cgatagacac accgaggatt
     1981 gcattcgcac ccaatttacc tttgttagga gtaccgtcaa gtgcaatcat agcacggtca
     2041 atagcttgtt gatcacgtac atcgtagcca atgatagctt cagcaatgat gttgtttacg
     2101 ttgtcaacag ctttttgtgt accaagacca ccgtaacgag atttgtcacc gtcgcgaagt
     2161 tcaactgctt cgtgttcacc agtagaagct cctgatggaa ccataccacg tccgaaagca
     2221 cctgattcag tgtaaacttc tacttcaagt gttgggttac cgcgtgagtc taggacttcg
     2281 cgagcgtaaa catcagtaat aattgacatt ttttactctc cttatgagtt aaatttttta
     2341 cacctctata ataccttaaa acccctcctt tttcaagaaa aaacgttatc tttgtgcaac
     2401 ttttccttaa ctttataaag taatcgcttt cttttgtctg ttttattcta acttttatga
     2461 tatactgttt tcatgacaga tttatcaaaa caattacttg aaaaagctca tggtgggtta
     2521 aaaataaatc cggatgagca aagacgctat cttggtactt ttgaggaaag agttcttgga
     2581 tatgtagata ttgacacagc aaatagccct cagttagaaa aaggcttttt atttatttta
     2641 gaaaaccttc aggaaaaagc aaagccacta tttgtgaaga tttcaccaac tatcgaattt
     2701 gataagcaag ttttctactt aaaagaagca aaagaaactg atagtcaagc caccatagta
     2761 tctgaagagc atattacttc tccttttggc ctggttattc atagcaatgc accagttcaa
     2821 gtagaagaaa aagaccttcg acttgctttt ccaaaacttt gggaagttaa aaaggaagaa
     2881 ccagccaaaa catccttatg gaagaaatgg tttagctaaa tcttgcacat atttaataag
     2941 tgcccaatat tggcagccgt gcgctccaga tagagactgg catttttcaa actatcttct
     3001 aaaggttcac ttttctccaa aatagaaaag acagcttgga tattttcaaa tggtagggga
     3061 ggtaaatctt cagcaagact accgcaaata gcaataacag gaactccaac aggggttctt
     3121 tttgcaacac ctataggcgc tttcccagca aagctttgac tatcaagtct tccttctcca
     3181 acaacaacca agtcagcatc tgaaactttc ttatcaaagt tgattaagtc caagcaggta
     3241 tcaattccag acacgatact tgcctgagca aaggcacaca aaccagcagc aatccccagt
     3301 cctccatcat tactggccgt gccaccaaca ccgatataaa tatctttaat ccctttagaa
     3361 atgagatgga gaatcaactc tccaatacca caagtttgga tttgaagtgg atttcgtttc
     3421 tctagcggaa tttttccaag accaaccaag tcagctactt caaatagtgc cagttcccct
     3481 ttttgaaaat agcgcatggc ttctttttgt ccaaaagggt ctgtcacttg gatccatttt
     3541 tcttttaggt caagagaatg tcggatagca tctacagtac cttctccccc atcaccaaca
     3601 gggcagagga gacattctac atctgctatc gattgttgga agcctctttt tattgcttca
     3661 gctacctgtt gagctgtcaa gctttcctta aacgaatccg gtgcaattac aatcttcata
     3721 ttttccctca ttctaaacag tcaatcaaag gaagaacttc taaaaaatcc ctcttgtcaa
     3781 catgatgtgg tatttctttt ttgagcattt ctttggaaca aaaggcgatt cctaactccg
     3841 ccgacttcaa cattaataga ttattaaccc catcaccgat tgccaccgtt ctttctttag
     3901 aaagttttag tttctttctc catttttcca gagtttcttt tttgacctgg ggacttataa
     3961 tttgtccaac taattttcct gttaaaagac cttctttgac ttcaagctgg ttggcagtga
     4021 aataggcaat accaagggat tttgctaatc tctccaacta ttggtgtaaa tccaccagac
     4081 accagaccaa ctaggatgcc attcttttgg agaatagaga tgaactctgg gacatttagc
     4141 gatagatgaa ttgagttgaa gacgttatca aagaccaaaa taggaagacc ttccaacaag
     4201 gacactcttt ttcttaaact gctttcaaag accaactctc ctcgcattgc tcgacttgta
     4261 atctgcgaaa tttccgcctc atgacctgcc tctctcccta aaagatcaat cacttcttct
     4321 aggattaagg ttccatctac atccaaaaca cacaagcctt ttacttgaga catcagttct
     4381 cctctctaaa cagcctaaaa atcgtatgaa gtcatcatac gattttatct attaattaac
     4441 taaactatgg tacaagtcaa ggtatgactt gcaggctgta tcccatgaga agtcactctc
     4501 catagcttgt ttttgtaggt ttctccaaat gtctggatgg tttctataca agtccaatgc
     4561 tgtttggaaa gtccaattta accaataagg agatagattg tcaaagctaa agccagtacc
     4621 gcttccttcg attggattga aagcgcgaac tgtatctcgc aagcctccaa cttcatggac
     4681 caatggcaag gttccataac gcatagccat catttgagac aagccacacg gttcaaaacg
     4741 acttggcatg aggaagaggt cacaagcagc gtagatttcc tgagcaagtt tgacatcaaa
     4801 agtgatattt gctgatagct tgtctgggta aatctgagca aaccatgaga aagctccttc
     4861 aaaggctgga tcgccagttc ccaaaagaac aatctgaaca tcttcttgca agatatggtg
     4921 aagactttcg accaccacat caaaaccttt ttgacgtgtc aaacgagaaa caattcccac
     4981 cagtggaacg tctgctctaa caggcaagcc aactctttct tgcaattttg ccttattttt
     5041 ggctttccca gacaaatctt cctgattgaa atgatagtct aaaagagcat ccgtctgagg
     5101 attataaaga tcagcatcaa tcccattcac gataccagat actttaccag actccatttt
     5161 aagaatctga tccaaattac atccaaactg actagtcata atttcatgag catagctagg
     5221 tgaaacggtt gaaacacggt tcgcatagag aatacctgcc ttcatccagt tcagacagtt
     5281 gttccatcga agggtgccat cagcgtaacg ttcaaggcca actccaaaca aatcacccaa
     5341 cattccttct gaaaattgtc cttggaattc taaattatga atggttaaaa ctgtttcaat
     5401 gtcctcatag gcttgaatcc aacagtattt ttccttcaac aagaaaggaa tcatagctgt
     5461 atggtagtca tgaacatgga gaagatcagg aataaagtca atcctttcca tagcctcaat
     5521 ggcagccagt tggaaaaagg caaagcgttc tccgtcatca aaatcaccgt aaacatgacc
     5581 acggaagaaa taatattgat tgtcaataaa gtagaaggtt acaccattta atactgtttt
     5641 cttaattcca caatactgtc tacgccaacc aacgctcacc tcaaaatgaa gcacatcttc
     5701 aatctgattt ccaaatttag cctctaccat atcatagtag ggtaaaatca ctgcaacttc
     5761 gtgcccagct tttaccagtg attttggaag agcgccaatg acgtctccca aaccacctgt
     5821 ttttgaaaag ggtgcaccct ctgctgctac aaataaaatt ttcatgaatg aatatcctct
     5881 gttactttag cacctttctt aaccacaact ggatgttctg cagttcctcg aatcacaaca
     5941 ccaagctcaa cttcaacccc tttgtccaag atagcatatt cgacctgagc cccttctcca
     6001 ataacaacac gagggaagag caggctatct ttaaccaagc tatccttatg gacatgaata
     6061 ttacgtgata gaacagaatt agctacttga ccttcaataa tactaccaga ggcaaactga
     6121 gaagtgctta ccttagatgt attagcatag taagttggct cttcgttttt gacctttgta
     6181 taaatctttt ggtttggtga gaaaagagaa tagaattttt gtgattcaag catatcgata
     6241 ttcgcttgat aataagattt aacagagtga atattggcta gatagcccgt gtactcgtag
     6301 gcaaaagctc cctcttttac agccaaatcc cgtaaaacat agcgcaattt ctctggatgt
     6361 tcttttttag cttcttcttc caagtgttca atcaaccaag gtgtatcaac gacaaagata
     6421 tctgtagaca tattgaacgt ttcagctgtt gacttgctat caaagagttt atgagaaaga
     6481 acatggtctg tttcatctac atccaagatt gcatttactt ctgaaatatc tttcttagct
     6541 agttttttat aaactacagt gataggctct tttgttgtac tatgtaggtg gaaaacttgg
     6601 ttcaaatcaa tgttaataag aacatcgcag ttgagggcaa ccgtttggtt tgagccagaa
     6661 cgtttcaaat aagtaagaag ctgttggtag tattcttttc caactgtact actttctaca
     6721 cgggtattgt aaattcctag atagtaatgg ctaagaaggg ttgataagcc ccactcgcgc
     6781 cctgaacgaa tatggtcaaa gactgagctg atattatcct gctggaaaat accaaagaca
     6841 ctacgaacac ctgcattagc aaggcttgaa agtgggaagt caatcaaacg atatttccca
     6901 ccaaatggca aacttgctac tggacggtgg tccgtcaatg tcgacatatc gtgaaaacca
     6961 actgtatttc ctaaaatggc agaatattta tcaatcttca tctgttgcta cccccactac
     7021 ttcattatat cctacaactt gtacttcatc tgttccatca atttcgacac cgtcagaaat
     7081 aatcgcacct tcaccaataa tggcacgttt aatcttagct ccttgaccaa tgatagctcc
     7141 actcatgata actgaatcaa ggacttccgc tccttcgcga acttgcgcgc ctgttgaaag
     7201 gatagaatgt ttaacagttc catcaacgaa acatccgtct acaactaatg agtcttccac
     7261 atgagcattt gccccgagga agtttggtgg tgaaatcaag tttcttgagt aaatcttcca
     7321 ttgacggtta cgactatcca aggcattttc tggagaaata tactccatgt tcgcttccca
     7381 aagtgactca atagtaccaa catctttcca ataaccacta aattcataag cataaacact
     7441 ttcacctgac tcaaggtaat ttggaatgac atttttacca aagtctgaca tgccaacctt
     7501 gctcttttca gcagcgacta acatattacg aaggcgttgc caatcaaaaa tgtagattcc
     7561 catagaagct tttgtagatt taggttgagc tggtttttct tcaaattcaa caatacgatt
     7621 gttagcatct gtgttcatga taccaaaacg gcttgcttct ttaagaggga cgtctaaaac
     7681 tgctactgtc aagctggcat tattatcctt atgagactgg agcatatcat catagtccat
     7741 tttgtagatg tgatccccag acaaaatcaa gacatactca ggattgacac tgtcgatata
     7801 gtcgatattt tggtaaatag cgtgactagt cccctcaaac caacgatttc cttcacttgc
     7861 agaataaggt tgaagaatag agacacctga attaataccg tctagtcccc agcttgaacc
     7921 attcccaata tggttgttga gagcaagtgg ttgatactgt gtaacgaccc caacattatg
     7981 aatccctgag ttggcacagt ttgatagggc aaagtcaatg atacggtagc gcccaccaaa
     8041 ttgcacagct ggttttgcga tgctttgagt gagtttaccg agacgagttc cttgcccacc
     8101 agcaagaatc aaagctaaca tttcattttt cattttctac tcctttttgg tttttatttg
     8161 tgacggtttt agtagatttc aagcgacgtt tgattttcca tacacttgct cccatagccg
     8221 gtagggtaaa ggttaaggtc tgctcataat ctttccatag tccttcttgc gtttgaacag
     8281 tttgattatg ttctttccaa acgcctcccc actcttccaa ctcagtattc catacttctt
     8341 cgtaaattcc tgcaacgggt agtccgattg taaaatcttt ccgctcaaca ggtaccatgt
     8401 taaagataca gactaacatt tctccctttt tacccttacg aataaaggaa agaacactct
     8461 ggtctcgatt atccgcatca atgatttcaa taccatcata gctggtatcg atttcccaca
     8521 gacagcgatg atctttgtaa aactggttta gctgagaagt gaaatacttc atcttagcat
     8581 tcattgggtc ttctaggtta gaccattcca actgttcttc agatttccat tctaggaatt
     8641 gaccgtattc gctacccatg aagagcaatt tcttaccagg atgacaaatt tggtacgtat
     8701 agagattgcg caagcctgcg aattgattgt aacgatctcc ccacatctta tgcatcatac
     8761 tcttcttgcc atgaaccact tcatcgtgcg agaatggcaa gagataattc tccttgaaaa
     8821 catacataaa gctgaaagtc accaggttaa agtcatattt acgatagatc ggatcttctt
     8881 cgtagaaacg gaggatatca ttcatccagc ccatgttcca tttgtagtca aatcctagac
     8941 caccaatctc tttcattccc gtaatcttgg tcgcagacga actttcttct gcaatcatca
     9001 tcacatctgg atattctaac ttaataacct cattcaagcg ctgaaggaaa taataacctt
     9061 catagttgag atttccgcca tctttattag gtgtccatgg agcatcatca tagtccaaat
     9121 agagcatgtt gctaacagca tccacacgaa taccatccaa atgatagaca tcaatccaat
     9181 gcttaatgca agaaattaag aaggactgga cttcattttt tccaaggtca aaattaaggg
     9241 caccccaacc atggttatga gccttattat ggtcttggta ttcaaaagtc ggtgtcccat
     9301 cataataggc taaggcatca tcgttgatgg taaagtgacc tggtacccag tccacaataa
     9361 ccccaatatt atgggtatga cactcctcga caaaatcttg aaactcctct ggtcggccat
     9421 aagcatgctc taaagcgaag taacccataa gctgataccc ccaactcaag cccaaaggat
     9481 gggacatcaa gggcataaac tcaatatgag tatagttcat ttcaacgaga taaggaatga
     9541 gttcatcctt gagctgggca aaactataag gactgccatc agaatttctt ttccatgatc
     9601 cagcgtgaac ttcataaata ttgacaggac gctcttcaaa gccccaacgt tttcttcgtg
     9661 ccagccaaag tccatccttc catttcttct cacgaagctc tgttaagatt gcccctgttc
     9721 ctggacgagc ctcatacctg acagcaaaag ggtcaatctt catcagttga tgaccatttt
     9781 gacgtgtgac atgatatttg taaatatgcc cttcttgagc catattggta aagacttccc
     9841 agaccccaaa atcatttctt accattggaa tctgattttc aatccagttg gtaaaatcac
     9901 caaccaagtg aacagcctga gcattaggtg cccaaacacg gaaggtatag ccatgctctc
     9961 catttagttc ttccctatgt gctcctagat aatgttggag ataaaaattt tcacccgtca
    10021 taaaggtttt taatgcttct ctattatcca tatactcccc ttctcctgta agcgttttct
    10081 atgtttttat tatactacct ttttagagaa gattcaagta aattactata cttctttaat
    10141 tattttgaaa atctacaaca agttcactta ctcgttcaat tgtaaatcaa tattttttca
    10201 aaaaattgcg aaaactcctt tctttttcta
//
LOCUS       DBEJJV010000061         9756 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.061, whole genome shotgun sequence.
ACCESSION   DBEJJV010000061 DBEJJV010000000
VERSION     DBEJJV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9756
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.061"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            132..3233
                     /locus_tag="ACL3GT_001967"
     CDS             132..3233
                     /locus_tag="ACL3GT_001967"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HGR0517568.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVSYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3316..4323
                     /gene="pfkA"
                     /locus_tag="ACL3GT_001968"
     CDS             3316..4323
                     /gene="pfkA"
                     /locus_tag="ACL3GT_001968"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HGR0517569.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4382..5887
                     /gene="pyk"
                     /locus_tag="ACL3GT_001969"
     CDS             4382..5887
                     /gene="pyk"
                     /locus_tag="ACL3GT_001969"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HGR0517570.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6632..6847)
                     /locus_tag="ACL3GT_001970"
     CDS             complement(6632..6847)
                     /locus_tag="ACL3GT_001970"
                     /inference="COORDINATES: protein motif:HMM:NF012920.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S24 family peptidase"
                     /protein_id="HGR0517571.1"
                     /translation="MEPKIRNSDYLFIKNTPQIDYNTIGIFQVDGTNYVKKLRQGYLK
                     KTQSRILRHPPRRKQPYSYHRKSCQAI"
     gene            7695..8567
                     /locus_tag="ACL3GT_001971"
     CDS             7695..8567
                     /locus_tag="ACL3GT_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HGR0517572.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8713..9057)
                     /locus_tag="ACL3GT_001972"
                     /pseudo
     CDS             complement(8713..9057)
                     /locus_tag="ACL3GT_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9200..9512
                     /locus_tag="ACL3GT_001973"
                     /pseudo
     CDS             9200..9512
                     /locus_tag="ACL3GT_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9516..9756
                     /locus_tag="ACL3GT_001974"
                     /pseudo
     CDS             9516..9756
                     /locus_tag="ACL3GT_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
BASE COUNT         3027 a         1688 c         2073 g         2968 t
ORIGIN      
        1 atataaaaat gatgacaaaa atacaaatga atagaaaata aattagtaag ctgatgaaat
       61 ttttctcaag agaagccatt tataggtgaa aatggtataa tatagtgaga aggatagagg
      121 agaagtgtaa attgatcgca caactagata caaaaacagt ctatagtttt atggaaagcg
      181 tcatttcgat cgaaaagtat gtgagagcag ctaaagaata cggctacact catttggcta
      241 tgatggatat tgacaatctt tatggcgctt tcgactttct agagattaca aaaaaatacg
      301 gcattcatcc tttgctaggg cttgaaatga cagtgtttgt agatgatcag gaagtgaatt
      361 tgcgcttttt agctctatct agtgtgggct atcagcagtt gatgaagctt tcgacagcca
      421 agatgcaggg ggagaaaact tggtcagtcc tgtcccagta cctggaggat atcgcggtca
      481 ttgtgtctta ttttgataga gttgagtcgt tagaactagg ctgtgattac tatatagggg
      541 tttatccaga aacactagca agcgaatttc atcatcctat cttacctctt tatcgggtca
      601 acgcttttga aagcagggat agagaagttc ttcaagtttt aacagcgatt aaagaaaatc
      661 taccgctcag agaagttccc ttgcgttcga gacaagatgt ctttatatca gcaagttctt
      721 tagagaaact attccaagag cgttttccgc aagctttgga caatttagaa aagcttattt
      781 caggcatttc ttacgacttg gatactagtc tgaaactgcc tcgttttaat ccagctagac
      841 cagcagtaga ggagttgaga gagcgtgctg aactggggct tgttcagaag gggttgacta
      901 gtaaagaata tcaagataga ctagaccaag aattgtctgt tattcatgat atgggctttg
      961 atgattattt cttggttgtt tgggatttgt tgcgttttgg acgatcgaat ggctattata
     1021 tgggaatggg aaggggttct gcagtaggca gtttggtttc ttatgcctta gacatcacgg
     1081 ggattgaccc agtagagaaa aatctgattt ttgaacgctt tcttaatcgt gaacgctata
     1141 ccatgcctga tattgatatt gatatcccag atatttatcg tccagatttt atcagatatg
     1201 ttggtaataa atatggtagt aaacatgcgg cacaaatcgt tactttttca acctttggag
     1261 ccaagcaagc tcttcgagat gtcttgaaac gctttggtgt gccagagtat gaattatctg
     1321 caattactaa gaaaatcagt tttcgtgaca atcttaagtc ggcctatgag ggcaatctcc
     1381 agtttcgtca gcaaatcaat agtaagttag aataccaaaa agcttttgag attgcttgca
     1441 agatagaggg ctatccaagg caaacctctg tccatgcggc tggtgttgta attagtgacc
     1501 aagatttaac caactacatt cctctaaagt atggtgatga aattccactg actcagtatg
     1561 atgctcatgg agttgaggct agcggacttt tgaagatgga ctttctggga ctacgaaatt
     1621 tgacctttgt ccagaagatg caagagttgc ttgctgaaac agaaggtatt catctgaaaa
     1681 ttgaagaaat cgatttagaa gacaaagaaa cgttagcttt atttgcctct ggtaatacaa
     1741 aaggtatctt tcaatttgag caaccaggtg ccattcgtct gcttaagcgt gtgcaaccag
     1801 tctgttttga agatgtcgtc gcgactactt ctctaaatcg accaggtgca agtgactaca
     1861 tcaataattt tgtggcaagg aagcatgggc aggaagaagt gactgttcta gattcagctc
     1921 tggaggatat tttggctcca acttatggca ttatgctcta tcaggagcag gttatgcagg
     1981 ttgctcagcg atttgctgga tttagtcttg ggaaggccga tattttgcgt cgagctatgg
     2041 gtaaaaagga tgcctctgct atgcatgaga tgagggcttc ctttattcaa ggctccatag
     2101 aagcaggcca tactgcggaa aaagcagagc aggtttttga tgttatggag aagtttgcag
     2161 gttatggatt taatagatct catgcctacg cctactcagc cttggccttc cagttggctt
     2221 atttcaaaac gcattatcca gccatttttt atcaggtcat gttaaattat tccaacagtg
     2281 attacttaat agatgcactt gaagcaggtt ttgaagtagc ctctctatcc atcaatacta
     2341 ttccctatca cgataaaatt gccaacaagt ctatctatat aggtttgaaa tcgattaagg
     2401 ggctcagcaa ggacttggcg ctttggatta ttgaacatag accttattct aacattgaag
     2461 attttatagc taaattacct gagaattatc tgaaacttcc tctgctagaa cctttggtaa
     2521 aagttggtct tttcgattca tttgaaaaaa atcgtcaaaa agtatttaat aacttagcta
     2581 atctatttga atttgtgaaa gagttgggaa gtttgtttgg agatgctatt tatagttggc
     2641 aggaatcgga agattggacg gaacaagaaa aattttatat ggaacaagag cttttaggga
     2701 taggtgtcag caaacatcca ctacaagcta ttgcaagtaa ggctatttac ccgattaccc
     2761 caatcggaaa tttgtcagaa aatagctatg ctattatttt ggttgaagtt cagaaaataa
     2821 aagtgattcg taccaaaaag ggtgaaaata tggccttctt acaggcagat gatagtaaga
     2881 aaaaattgga tgtcactctc ttttcagact tatatcgtca ggttggacag gaaataaaag
     2941 agggagcctt ctactatgta aaaggaaaaa tacaatcacg tgatggccgt ctgcaaatga
     3001 ttgcacaaga aataagagaa gcagttgctg aacgcttttg gatacaggtg aaaaatcatg
     3061 aatcggatca agaaatttca cgcattttag aacaatttaa aggcccaatc ccagtcatca
     3121 tccggtatga agaggaacag aaaaccatcg tttctcccca tcattttgta gctaaatcca
     3181 atgaattaga ggagaaattg aatgaaatcg ttatgaaaac gatttatcgc taaaaatacg
     3241 gaaaatagaa gaattttaaa atcaaatgtg atataatcaa gaagaatgtt aaaagaaaaa
     3301 ggagcataaa ccaatatgaa acgtattgct gttttgacta gtggcggaga cgcacctggt
     3361 atgaacgctg ccatccgtgc agttgttcgt caagcaattt cagaaggaat ggaagtgttt
     3421 ggtatctatg acggatatgc tggtatggtt gccggtgaaa ttcatcccct agatgcagct
     3481 tcagtagggg acatcatttc tcgtggtggt acttttcttc actcagctcg ttatccagag
     3541 ttcgctcaac ttgaagggca acttaaaggg attgagcaat tgaaaaaaca cggaattgaa
     3601 ggtgtagttg ttatcggtgg tgacggatct taccacggcg ctatgcgttt gactgaacat
     3661 ggcttcccag ctattggtct tccaggtaca atcgataacg atatcgttgg tactgacttt
     3721 acaatcggtt ttgacacagc ggttactact gccatggacg ctatcgataa gattcgtgat
     3781 acatcatcaa gtcaccgtcg tacttttgta atcgaagtta tgggacgtaa cgctggtgat
     3841 atcgctcttt gggctggtat tgcaactggt gctgatgaaa tcatcatccc tgaagcaggc
     3901 ttcaagatgg aagatatcgt agcaagcatc aaagctggtt atgaatgtgg taaaaaacac
     3961 aatatcatcg tcttagctga aggtgtgatg tcagcggctg aatttggtca aaaacttaaa
     4021 gaagctggag atacaagcga ccttcgtgta acagaacttg gacatattca acgtggtggt
     4081 tctccaactg cgcgtgaccg tgttttggcg tcacgtatgg gtgcacatgc tgttaaactt
     4141 cttaaagaag gtatcggtgg tgttgcggtt ggtattcgta acgaaaaaat ggttgaaaat
     4201 ccaattcttg gtactgcaga agaaggggca ttgtttagcc ttactgcaga aggtaagatt
     4261 gtggttaaca acccgcacaa agccgatatt gagctatcta gcttgaataa gagcttgtca
     4321 taatttacaa tttagttaat aagaccaaaa aggtcatata tataaaggag tcacaaaaat
     4381 catgaacaaa cgtgtaaaga tcgttgcaac tttgggtcct gcggtagaaa tccgtggtgg
     4441 taaaaaattc ggtgaggacg gatactgggg tgaaaaactt gatgttgaag cttcagctaa
     4501 aaacattgct aaattgattg aagctggtgc taacacattc cgattcaact tctcacacgg
     4561 cgaccaccaa gaacaaggtg agcgtatggc aactgttaaa cttgcggaaa aaattgcagg
     4621 taaaaaagtt ggtttccttc ttgatacaaa aggacctgaa atccgtacag aattgttcga
     4681 aggtgaagct aaagaatatt catacaaaac tggtgaaaaa attcgtgttg caactaaaca
     4741 aggaatcaaa tcaactcgtg aagtgattgc gttgaacgtt gctggtgctc ttgatatcta
     4801 tgatgatgtt gaagttggtc gtcaagtttt ggttgacgat ggtaaacttg gtcttcgtgt
     4861 ggttgctaaa gatgatgcaa ctcgtgaatt tgaagttgaa gttgaaaacg atggtatcat
     4921 cgctaaacaa aaaggtgtga acatccctaa cactaaaatt cctttcccag ctcttgctga
     4981 acgcgataac gacgatatcc gtttcggtct tgaacaaggt atcaacttca tcgcaatttc
     5041 attcgtacgt actgcaaaag atgtgaacga agttcgtgca atctgtgaag aaactggaaa
     5101 cggacatgtt caattgttcg ctaaaatcga aaaccaacaa ggtatcgata acttagatga
     5161 aatcatcgaa gcagctgatg gtattatgat tgctcgtggt gatatgggta tcgaagtacc
     5221 gttcgaaatg gttccagttt atcaaaaaat gattatcaag aaagtcaatg ctgcaggtaa
     5281 agttgttatc actgcaacaa acatgcttga aacaatgact gaaaaaccac gtgcaactcg
     5341 ttcagaagta tcagacgtat tcaacgctgt tatcgacgga actgacgcta caatgttgtc
     5401 aggcgagtct gcaaacggta aatacccact cgagtcagta actacaatgg ctacaatcga
     5461 caagaacgct caagctcttc ttaatgaata cggacgtctt gattcagatt catttgagcg
     5521 taactctaag acagaagtaa tggcttctgc tgttaaagat gctactagct caatggatat
     5581 caaattggtt gtaactctta ctaagacagg tcatactgca cgtttgattt ctaaataccg
     5641 tccaaatgct gacatcttag cattgacatt tgacgaattg acagaacgtg gcttgatgtt
     5701 gaactggggt gttatcccaa tgttgacaga tgctccatct tcaactgacg atatgttcga
     5761 aatcgctgaa cgtaaagcgg tagaagcagg tctcgttgag tcaggcgatg atatcgttat
     5821 cgttgctggt gtgccagtag gagaagctgt tcgcacaaac acaatgcgta tccgcacagt
     5881 acgttaagaa aaatataaaa acctatcata tccagctttc tagcctgtat gatgggctct
     5941 ttttttgtcc agggggcaaa aagggggcaa aactttcata atggattgat actcttcgaa
     6001 aatcaaattc aaaccacgtc agcgtcgcct taccgtatat atgttactga cttcgtcagt
     6061 tctatctaca acctcaaagc agtgctttga gcaacctgcg gctagcttcc tagtttgctc
     6121 tttgattttc attgagtatg aaataagata tgcataaatt gattagaaag tcaaatgaat
     6181 ttctacaaat gttttagcaa tcgcaatcta cttgtctaga ttcgatctga tatattttcg
     6241 atttaatgat atggtattta aaacctccaa agtagcttgc tccattcttt tacctacgtg
     6301 agtctagatg ttatttactg ttttagcgtt tttgtgttct actctaacca ttatagcatt
     6361 cttctcagct agtgtactaa ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt
     6421 tatcggtttc tctagtttag tatttgcctt ttgcaaagtg atcttaaatg cctttctcta
     6481 aatttacata tcactattgt ttaacaaaat ctaatctatt ttaggtcact tattcttttt
     6541 ttgaaatgta gaatgaactt tttcaaagtt tttcgaatct tttaaaatct gtttgtttta
     6601 tatcgccatt ctcccccttt tttaattctc cctatatagc ctgacaactt ttccgatggt
     6661 acgaatatgg ttgctttcgt ctaggtggat gtcggagtat tcgggattga gtttttttga
     6721 ggtagccttg gcggagtttc ttgacatagt tagtgccgtc tacttggaag atgccgatgg
     6781 tattatagtc aatctgtggg gtattcttga taaataggta gtcgctgttt cttatctttg
     6841 gctccatgga cttgctgacg acataagcga ttgggtcgta gtcgtctggg ataatggaaa
     6901 ctccataact aaatcgtcgt cctgcatcaa gcggctacct gcagagataa actacctaac
     6961 acgagagtaa gtagtctgtc tgtagtcgtc cagtctgatg atttttacga tacttcgttt
     7021 ttctgatcat acagttgcct ctcggcatag gtcagaactt taccttgtct gggtggtgcc
     7081 cgttggtcgt agatagattg gatatcgcta ggagaatcct tttgaactgg aggaaagagg
     7141 gcatcaatca agctactgaa tactttaact aagtcaaata tagtattttt cttagtagac
     7201 ctaacccttt tttcataatt tctaatggtg tttttactta tacctatctt agtacccaat
     7261 tcttattgag tccaaccatt actagtctat attgttttat agttgattga gtttggaata
     7321 gtacgctgta gctgctaaaa catttctagg aattaatttg cctttcctaa tagagttgtt
     7381 catatcttat ttcaatctac tatatttttc acctctaaca atcgcaatct cttctttatc
     7441 catgaacgaa aacgctttct atctttgtaa gtaaagcatc acacgaaatc cacgaaaatg
     7501 aaaacctttg ttgtgttttc gtaaaaaatt tgttgacaga gcacgaaacg cctactataa
     7561 ttaaatcaag tttaaggaaa taacaaaaaa acaaatcgga gggaaagacg atgaacacat
     7621 taaatgagaa agtaatcaat atctgtaaag cagtagttaa agaaacttta atccaagaca
     7681 tttaggagaa agaaatgaag aaatcaagaa aattagccac attaggaatc tgttcagcct
     7741 tgtttttagg cttggctgct tgtcaacaac aacatgctac ttctgagggg acgaatcaaa
     7801 ggcaaagcag ttcagcgaaa gttccatgga aagcttcata caccaaccta aacaaccagg
     7861 taagtacaga agaggtcaaa tctctcttat cagctcactt ggatccaaat agtgttgatg
     7921 cattttttaa tctcgttaat gactataata ccattgtcgg ctcaactggc ttatcaggag
     7981 atttcacttc ctttactcac accgaatacg atgttgagaa aatcagtcat ctctggaatc
     8041 aaaagaaggg cgatttcgtt gggaccaact gccgtatcaa tagttattgt cttttgaaaa
     8101 attcagtcac cattccaaag cttgaaaaga atgaccagtt gcttttccta gataatgatg
     8161 cgattgataa aggaaaggtc tttgattcac aagataagga agagtttgat attctatttt
     8221 cgagagttcc aactgaggca actacagatg tcaaggttca cgctgaaaag atggaaacat
     8281 tcttctcaca atttcaattc aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca
     8341 atctggatgg cgagtatctg tttgtaggcc acgttggggt cttagtacct gctgatgacg
     8401 gtttcttatt tgtagagaaa ttgactttcg aagagcccta ccaagcgatt aaatttgcta
     8461 gtaaggaaga ttgctacaag tatttaggca ccaagtatgc ggattataca ggcgagggac
     8521 tggctaagcc ttttatcatg gataatgata agtgggttaa actttaatag tgttatgata
     8581 tgacagtaat cttaggattt ttatttctat ttttgatgag ttggtgggtt atttcaatcg
     8641 ttaatagcca gaaaccacgc aaaaatgaaa catttattgg ctatatccaa agatacgata
     8701 ttgatgggaa tggctatcaa tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat
     8761 cgtaaaacta ctttgaacaa gagttacttc aacccattgg ctccgacgga ttaagttgct
     8821 ttcgtgaaca ccaaaatcag ccgcaatttc ttcataagtg cggtattctc gcacatattg
     8881 aagagtggcc ataagaaggt cttctaggct taatttaggt tttcgtcccc cttttgtgtg
     8941 tttaagttga taagcagttt ttaatacagc taacatctct tcaaaagtgg tgcgctgaac
     9001 accaacaaga catttaaatc gtgcatcagt tagttgctta cttgcttcat aattcataga
     9061 actactatac catattttgt ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag
     9121 atttcttaaa gtttattctt tgtagtttca tctgtattag tacataattt aacttagaga
     9181 aaataggagg attaatcgaa tggaattaaa agattttaca gaaaaagaac aggaaatgat
     9241 taagaaaagg cttacaatgt ctaatattag tgacaaagaa actactgaga agattctggc
     9301 gctagtacca caagacttga ttaagcgaat cccgtttttt gtcagaaaac atgctacaac
     9361 acgtacgatt aaacgcattt caattgaaca ccctgaactc tacgctgtag ctcaaacaag
     9421 tggtgagatt ccagaaaaaa aaacgcgaag aattgcgtca gattatcaca actatctttg
     9481 aacaaaagat gaataagcat agtattaagt agagaatgaa aaaatatttt attggcggtt
     9541 tgggaagcaa tgcctatcat agcaaggatt ttctttaaga actagattcg caggtctatt
     9601 ttctaaatcc atatgaaaag catcttcgag atgaaacaga attgaaatca tggtttaaaa
     9661 atgagattgt agaggaagaa tctatctgtc tgataggtca ttctattgga ggcgatttag
     9721 ctcgttattt cgcatcggaa tttgaagaag taaaga
//
LOCUS       DBEJJV010000062         9741 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.062, whole genome shotgun sequence.
ACCESSION   DBEJJV010000062 DBEJJV010000000
VERSION     DBEJJV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.062"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            34..642
                     /locus_tag="ACL3GT_001975"
     CDS             34..642
                     /locus_tag="ACL3GT_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HGR0517573.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            673..876
                     /locus_tag="ACL3GT_001976"
     CDS             673..876
                     /locus_tag="ACL3GT_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HGR0517574.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(986..1225)
                     /locus_tag="ACL3GT_001977"
     CDS             complement(986..1225)
                     /locus_tag="ACL3GT_001977"
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HGR0517575.1"
                     /translation="MNERYQCLKTKEYQALLSSKGRQIFAKRKIDMKSVFGQIKVCLG
                     YKRCHLRGKRQVRIDMGFILMANNLLKYNKRKRQN"
     gene            complement(2028..2798)
                     /locus_tag="ACL3GT_001978"
     CDS             complement(2028..2798)
                     /locus_tag="ACL3GT_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HGR0517576.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(2813..3661)
                     /locus_tag="ACL3GT_001979"
     CDS             complement(2813..3661)
                     /locus_tag="ACL3GT_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HGR0517577.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDNFEDPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTGLDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(3658..5133)
                     /locus_tag="ACL3GT_001980"
     CDS             complement(3658..5133)
                     /locus_tag="ACL3GT_001980"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HGR0517578.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVNFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(5456..6811)
                     /locus_tag="ACL3GT_001981"
     CDS             complement(5456..6811)
                     /locus_tag="ACL3GT_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0517579.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLNQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWHAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(6821..7138)
                     /locus_tag="ACL3GT_001982"
     CDS             complement(6821..7138)
                     /locus_tag="ACL3GT_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0517580.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(7155..7472)
                     /locus_tag="ACL3GT_001983"
     CDS             complement(7155..7472)
                     /locus_tag="ACL3GT_001983"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0517581.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(7487..8383)
                     /locus_tag="ACL3GT_001984"
     CDS             complement(7487..8383)
                     /locus_tag="ACL3GT_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HGR0517582.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(8386..9648)
                     /locus_tag="ACL3GT_001985"
     CDS             complement(8386..9648)
                     /locus_tag="ACL3GT_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0517583.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         3351 a         2030 c         1465 g         2895 t
ORIGIN      
        1 taaaaattac taatttaatt aaaggagttt catatgtcaa acgaaaaaaa cacaaacact
       61 aacgtagaaa agaaagatgc tactgttgta gctcacgaaa tcaaagggga acttacttac
      121 gaagataaag ttatccaaaa aatcattggt ctttcactag aaaacgtttc aggtcttttg
      181 ggaatcgatg gtggtttctt ctcaaatctt aaagaaaaaa tcgttaacag cgatgacgta
      241 acaagtggtg ttaacgtaga agttggtaaa acacaagttg cagttgactt aaacgttatt
      301 gttgagtacc aaaaaaatgt tccagcttta tattcagaaa tcagagaaat cgtatcttca
      361 gaagttgcta aaatgactga cttggaaatt gttgaaatca acgtaaacgt tgtcgacatc
      421 aaaactaaag aacagcatga agcagactca gtaagccttc aagatcgcgt atctgacgtt
      481 gctgaatcaa caggagaatt cacttcagaa caattcgaaa aagctaaatc tggtcttgga
      541 tctggtttct caactgttca agaaaaagtt agcgaaggtg tagaagctgt taaaggtgca
      601 gcaaatggtg tagtatctca cgaaaacact cgtgtaaact aagataaaat aaatataaca
      661 ggagaaatta tcatgtcagt agaagaaaaa ttaaatcaag ctaaaggttc tattaaagaa
      721 ggtgttggga aagccatcgg tgatgaaaaa atggaaaaag aaggagcagc tgaaaaagtt
      781 gtttctaaag taaaagaagt cgccgaagat gccaaagacg ctgtagaagg tgctgtagaa
      841 ggtgttaaaa acatgttgag tggcgacgat aaataaggtt aaaagttact ttatcttttt
      901 agtaacatta gtcaaaagag tctgagtcaa gatgattctc agaaaacaaa aagctagaga
      961 ttcccaattg cggaactcta gctttttaat tttgcctctt tctcttatta tatttcagca
     1021 ggttgttggc catgagtatg aatcccatgt caattctcac ttgacgctta cctctcagat
     1081 gacatctctt ataacccaaa caaaccttta tctgcccaaa gacagatttc atatcaatct
     1141 tacgtttagc gaaaatttgt ctacccttgg aagataaaag tgcctgatat tctttagttt
     1201 ttaaacactg gtaacgttca ttcatataca gtcccttttg aggggctgat tcaggttcat
     1261 aatcgcagtc aacattgatt tcaaggctgt ttgctttcta tctccccttt ttcatgatat
     1321 attttcgtac aggtgcttca atagtttcta tagtaaaatg aaccaaaaat agtacacgtt
     1381 gcggtataat gttcttgtgg catattcatt agattttcgt aaaaagttct ctcctatttg
     1441 tgagcgaaca ggtatagtca attgattgtc agtttgaaga ccaagagtcg taaggcaaag
     1501 gatatggcag aatccatcca agggtggctg gcacaatttc tagtgaacct ctttaaatct
     1561 attacgtttg actgtggaaa agagttttca aaatggaaag atatttccaa tcatcacgat
     1621 agtgagagct tttttgcgaa tctaggatgt ccaagatagc ggtgtctcaa cgaacattca
     1681 aatagacttt taaggtgtca tgacttgcca aagcagacag atttcaacga agtcagtcaa
     1741 gaattttagg ctgggcaaga actcaatttc aggagaaaat gaaataaata ttcccacaat
     1801 aaaacgcata gtatcaaagt ttttccaaca cctgatatta tgcatttttt aattttaaag
     1861 actttttccc agcctcaaga aatcacatcc cacctaaatc ctttggatac caaatacctc
     1921 atcaggttat tttctgagtt ggtaagactg tctagcttaa tttgacaaat ggagggcgtt
     1981 aaatccagtt tttacaggaa gtctatttaa atattttcac actgacctta caaaatatga
     2041 aataaattat ataaagtcat tcccatgaca aagaataaca tccctttaaa acagtatctt
     2101 acccaatttt caggtaagac ttttgataca accgtcccca atacccctcc gcatatagaa
     2161 gcaagaaaaa taactggaac aggtgctaaa tgatactgat ttaaacctgt aaccacaaca
     2221 attgtagcca aatgagacag ctgggaaaag aaaataattg caagagaata catcgttgct
     2281 tcttttatcg aaatagaaaa aaacaccatc aataaagata cattgagcgg acctccacca
     2341 atccctaaaa aactagaaat caagcccaat agaagaccac aaatcatata gaatcctatc
     2401 ttatcaaatt gataagtttt tttaaaatct gttaaaacaa atgatacaag tagcatcaca
     2461 aatagtaaaa tcatttgaac aatggatact agccgtactg ataattgaga taacaaaact
     2521 tgaaaaataa gatgacctag aaatcctcct aaaacagaag aaaaggatac cgtaaaaatc
     2581 aatctccatt ttatctcttt actttgtgaa aatcttttgg ttgttgaaat aatcgccatt
     2641 ataaaaacag agaaactaga ataaaaagca atatcactga ccgaatggta tccaaaacta
     2701 tccataagtg gcttaattat aattccacca cccatgcctg atatagaacc caatccacta
     2761 gctattataa tgattagaaa ataaataatc tcaaccactt tttaagtcca tcctattctt
     2821 tcaaacatct aaaacctaga tggctactag tggaagtaga aatacatcca tttctagcag
     2881 ctactcggta tcgattacaa taagaacaat gacataaaaa ggaacctcct ctgatagcat
     2941 actcctcatc ttgtatccca tattttggca actcatagtc atcttcatta aaactagcta
     3001 ataaggtata tctcggattg cgacaccatt cccaaacatt cccaatcatt tgatatagac
     3061 caaaatcatt aggtaaaaat tcatagacag gagccgttcc tataaatcca tctaagccag
     3121 tattttcata aggaaatctt ccttgccaag tattggcatg ataatatcca ccttctaaaa
     3181 gagtatctcc ccaaggatat tcagattgtc ttcctcctct agcagcgtat tcccactgtg
     3241 cttcagtcgg taaagacatt ccgctccaat tacagaaagc caatgcatct tctaaagcaa
     3301 catgaactac tggatggtct tctaaaccca ctagattact gttctcaccg tagggatgtt
     3361 tccagcaagc gttcggaact tgtaaccacc acggagcccc ggcaggatga ggatatccct
     3421 ccctttctgc ctccggaacg aacaatataa aaacaaaaga ccactcttgt cgctcagcta
     3481 gtgttttata gcctgtttct ttcacaaatt gagcaaattc ttgattcgta actggagtat
     3541 ccgcaatgga aaaatccttt acactaacag cgacttgagg atcttcaaaa ttatctaaaa
     3601 agccctcttc agaatttgtt cccatcataa atgtcccacc cttgattttt ttcattttca
     3661 tgattgacta tcccccgttt tcgttagagt tggcgttatt ttagaaagtt caacaggaac
     3721 taactcttca tccacaacaa aaccttcttc tctatatcta agaaagttta ctaatttttt
     3781 cttcatctga cgaacaatag gttggtattt ttcacttgga tacaaatcat tcatttcatg
     3841 cggatctttt ttcatatcaa ataactgata atgatttaaa acaggaaacc agataaattt
     3901 ccactggtct gtcaaaatat attgactaga atcttttcct aaagcatgtt caccatgaaa
     3961 ttctgttcgc cacccctcgt actgtccaaa taataaattc ttaacactcc gtccatctag
     4021 ttcatctgta gtagttcctc ctgccaaatc cacgagtgaa ggaaaaatat cttgaatttt
     4081 cactaattgc ttgattgttc ccctattacc agctatcaat ccagccggat cgtaaataaa
     4141 cgaaggaatg tggatacttc cctgataagg atatcccttt ctaaacagat aatgttcacc
     4201 aagctgatct ccatgatccg aaacaaacca gataatcgta tctttatcat gacgaaattc
     4261 ttttagggca gtcaaaaagc gactaatttg atggtctata tgagtaatca atccaaaata
     4321 agcagcaacc attcttcttt gatcatcttc ctttaatttc cctcttaaag cataaataga
     4381 cggaatttgc ttttctaata cttcccaatt cccgatatgc aaatcgagaa attgaggcaa
     4441 gcgttccata tacatatcaa aatagtattt tgggggattt aatggagcat gtggtttttc
     4501 aaaagacatt ttgagaaaaa aaggaaccgt tggatctctt ctttgtaaaa atgaaatgga
     4561 ctcactcaca acccagtttg ttggatgtaa cttttcatct ttatcccaag gtctagcttc
     4621 ccaagaatta caatccattc cgtcatcaat caaatcaaca tcataaccaa ctttaccctt
     4681 taaaaaggct agatagtcac tagcataatc aaattgactt ccataagcct tatcatactt
     4741 tctatcaaca tgtagatacc catcgtgaag taagacatga tcaaacccaa gtctctgtct
     4801 ggaaggaaaa acatgcatct taccaataca ctctgtttga taacccatat ctttaaagac
     4861 ttttggaaga gtattagtaa aattccaagg cacctcatct tgataaccaa cacgtccact
     4921 tttatcttgg tctaagccag tcaataaagc tgccctagca ggaacgcaag aaggaactgg
     4981 agaataggca ttttcaaaat tataacctac actagccatc atatctaatg ttggagtgct
     5041 aactagctta tccttactat tcaaggataa ggcgtctgct ctcatttgat ctacaacaat
     5101 caaaataata tttggctgtt ttgtctgaac cataaaatct cctttctaat atggcaaaag
     5161 aggcacaaga agatatctac ctttactgca cccctttcta tatcaatctc tctatataaa
     5221 acaataacat tcttgttatg ttttatataa aaatgaacta aaatatgact aaatcgatta
     5281 ggaaattcaa atcattttct agtactgttt tagaagttac agtgtactat tccaacttca
     5341 ataaactata aacctttgtc tattaacaat tttagtggag ataagaaatc ctacacctaa
     5401 ctcatcttac acgtaatcta tttctatttt atcacaaaaa acgcaagtaa gaccattaac
     5461 tcaattcagt tttatctgcc attttcacaa atgggaaata agtcaagaca ctaataatca
     5521 aacaaacaac tgataagatg atggcatgcc aatcaaatgc tgtagagaag aaaccatata
     5581 aaattggagg cattacccaa gtaacatttt gtgtaacagg tgaaacaaga ccccagcttg
     5641 ttgcccagta agctaccgtt gccatgaaaa ccgggctaag tacaaatggt ataaatagca
     5701 aaggattcaa gacaactggt aaaccataat tgaccggctc accaatatta aacagaactg
     5761 gtgctagacc aagtttagca acttttcgat aatgactgtt tcttgaaaaa attaaaatag
     5821 caagtactaa tcctaatcct ccaaaccaga caaacgcccc aaaagaccca cttgtccata
     5881 tataaggaat cggttcacct ttttggaaag catccagatt cgctaacata gcaactccaa
     5941 atagcccttc catgatggga gccaatacat ttcctccatg gagaccaaaa aaccagaata
     6001 acttattcaa aaagatcatc agaataactg caaagaaact ttgagacaaa cctagtaatg
     6061 gcgtttgtaa caccttgtaa acccaatcaa tcaataagtc attgctaagt aaatggaaaa
     6121 cataagtcaa gatggctact atatacatcg ccataaatcc tggaatgata gaagtgaacg
     6181 gcttagcaat cgcaggggga actgaatctg gtaacttgat tacccagttc tttttcatta
     6241 ctttacagaa aataatagag gctaaaaatc caatcatcat ggctgtaaag tatcctctgg
     6301 cattaatatg gtttcctgga atcacattcc caatagttac catcagattt ttaccatcaa
     6361 atgctagatt atcaattcct tgtaagattt gatttaattt cacatctcct acatttgcca
     6421 aagggaaact ctttgtaact gtacttccaa tcgaaatgac aaacgaagca agtgatacca
     6481 aaccagcaga aactgtatca accttgtaaa tcttagcgat attcactccc aagcaataga
     6541 tgaacaataa ggaaacaatt ggtatacttc ccttgaatac caaattattg atgtcaacaa
     6601 gccactgaaa ggttttcgta atactttcta ggtgaaattg ttgtggtaaa tccactagaa
     6661 aagcatttaa taacaaagca atggaacctg tcataataac aggcatagtc cccacaaatg
     6721 aatcacgtaa agcaactaaa aacttctgat tcccaacttt cattgcaatt ggagaaagtt
     6781 tttcttgcat tttatccaac attgtattca tagcaaattc ctaatttttt tcaaatcgtt
     6841 cgtatacttc taccacttct ttcgccaagt caacaaaggt cagactcgtc attaaatgat
     6901 cttgcgcgtg taccatcaag aggctaattg aagtttcttc cccctgtgcc tctcttgtca
     6961 acatttctgt ttgagcctta tgcgcctgta ataaggcagc attcgcatca gctaatcttc
     7021 gattggcttt agagaaatcc cctttttttg ctgcctgaat agcctccata gcattacttt
     7081 tggcttcccc accatacata attagcccca ttgcagattc taaattactt tcattcatag
     7141 cattctcctc aatcttagtc taataaactt tcagctaaat ctaagacttt agaaccattc
     7201 atcattccat aatctgtcat cggaataacc gccacaggaa tctgtctatc ttttagtttt
     7261 tcttgaaagt cccctagtaa atagcgaact tgagggccta aaagcaacac atttacttcc
     7321 tttgttgcta caatttcttc tgcttcagga gctggaactg caaaaatttc tgcatccaac
     7381 cccttatctt ctgctgcctt ttgcatcttt gtcactagca gacttgtact catacctgct
     7441 gcacatgcta acataattgt tactttagcc atagcttact cctttatcac ctatttactg
     7501 acctagccaa gcgagatact gtatgtctca ctcctctaat tgccttgctc aatgcataaa
     7561 tattatcgac tgttgccagt cccccatatc ctgcgtcacc tatatgttga atatcaactc
     7621 cacaaatttt atttctaagt gcaatttcct tgatagtatc tgtatcagat gtttcttggc
     7681 tagtaccaat agcactcagt actagcccac ccttactatg aacgagatca acgacttcac
     7741 gcaactcttg gtcatgaaag gctggaacgg ttccaactgc tggaacaagt atcacatccg
     7801 cacctgcttc caacaattgc tctgctacag aaagctctgc cacaggctca ttcactcctg
     7861 ccccgtgcat cttacctgca ataatcaaac cagaaaagtt ttccttagca gtttgaacag
     7921 ccttaatgat ttctcgattg ctaactcctg ttccaggatt tccagtcaaa cagacaaagt
     7981 caaaacctaa ctcctctatt cgattcaatg tttcaacact agcaacacga cctgcaacaa
     8041 tttcctgtgt ttcctctagc atctttgcag atgggtcaat cggttccaaa tttacaccaa
     8101 ttggacaagc aacaagctgg tgtaagcgat gaataacatc atcacctgaa ctatccaaag
     8161 cataaatttt aggctcaaaa acatcaacac aattcaataa aatcatatca gctccaaaag
     8221 ctctagcaat ttcagaatta gttatatccc caacaaatgt ctcacgagta actacatttt
     8281 cagatagaac aactctacct tcacttgcta aaatactttg ttttaattct tcagcattca
     8341 tctgtaatat ctcagatgga tttgcactaa ttaaacgttt cattctcaat cctccaataa
     8401 cttaaaccgt ttttcaatag ctattacaaa tggtaaataa agtaagacat ccaaaacaat
     8461 caatacaatt tgtaataatg aaccagaaat acttcctgta gcaagtaaac cacttataac
     8521 aggtggcata gtccaacctg gatctgtata agttagcgga accaaacctg atgccattgc
     8581 tccccacgct actagtaagt taaacattgg agctaagata aatggaacta gtaacaaaat
     8641 gttcaaaaca ataggaacgc caaacattgc tggttcattt atattaaata atccaggtat
     8701 aacagttata ggtgccaaag tttttagttg tttactagct ttcttcttat gtgctaaata
     8761 tcctaacgca agaactaaac ctatggttgc accaccgcca cctatgaata caaaattatc
     8821 cataaatacg ctagtaaaaa tatttggaag agtttctcca gtttgataag ctactttatt
     8881 tgcatctaga ttagctaacc ataacggttt cataactgca ttaacaacat ttcctccgtg
     8941 taatcctaca aaccaaaaac tactattaag gaaaattaag ataagaagac caataacatt
     9001 atttcctaaa agtccaagtg gacctcccaa agctacttga gcaatttcat gaagattagg
     9061 taaacttaat ttatctaaag ttgcataaac aatcaaccaa ccaacaatag tcactgcacc
     9121 aggaataatg gcactaaagc ttttagatac tgctggtgga acaccatccg gcatttttat
     9181 ctgtatatta tgatttataa accattggta gatatagcca ttaatcaatc ctaaaatcat
     9241 agcaacaaat aaaccttttg atgccatgaa agcggtaggc attcctgctc cagcctctcc
     9301 tctaatgaaa ggcgtaactg taataaaaga tgataatgac acaataccag caggaatacc
     9361 atcaactttg tattgtctag ccataaagta agcgatacca aaactagcta caagaccaag
     9421 taatccaaaa ctactatcaa cacccttcca taaatagtca gcaacaccaa tatcacccag
     9481 atatttttcc catcctggaa taggaaaact tgcaataacc attagtaatg aacctatcaa
     9541 caataaaggt atagttagag taataccgtc tcgaatagaa accaacgctt tattattacc
     9601 caatctagcc gctactggaa gtaacttttc ttgtaataat ttttccataa ccttttcctc
     9661 ttaaatatat tttattatca aaagttatca attatcttta ttttttgacg tcaagttgtt
     9721 atttgattat cttttgttat t
//
LOCUS       DBEJJV010000063         9730 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.063, whole genome shotgun sequence.
ACCESSION   DBEJJV010000063 DBEJJV010000000
VERSION     DBEJJV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9730
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.063"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            226..6660
                     /locus_tag="ACL3GT_001986"
     CDS             226..6660
                     /locus_tag="ACL3GT_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HGR0517584.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSKDTEEKKTTVIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDNRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
     gene            7292..7768
                     /locus_tag="ACL3GT_001987"
     CDS             7292..7768
                     /locus_tag="ACL3GT_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HGR0517585.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            7806..8111
                     /locus_tag="ACL3GT_001988"
     CDS             7806..8111
                     /locus_tag="ACL3GT_001988"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0517586.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8159..9634
                     /locus_tag="ACL3GT_001989"
     CDS             8159..9634
                     /locus_tag="ACL3GT_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HGR0517587.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLRGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT         3589 a         1460 c         1886 g         2795 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 ttagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca gttattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 acatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgca gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctattcgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagact taaagaaact cattaaaaag
     4441 aaatttagag aagttgatga ttttacaagt gaaactggta agagaataga ggaatacgat
     4501 tataaatacg atgataaggg aaatattatt gcttatgacg atggtagtgc cttacaatat
     4561 gaaactgaaa aacttgacga aataaaatca aaaatttatg gcgttctaag cccatctaaa
     4621 gatggacact ttgaaattct tggaaagata agcaatgttt ctaaaaatgc caaggtatat
     4681 tatggaaata gctataaatc gatagaaatc aaagcgacta agtatgactc acattcaaaa
     4741 acgatgacat ttgatttata cgctaatatt aatgatattg tggatggatt agcttttgct
     4801 ggagatatgc ggttttttgt taaagatgat aatcgaataa aagctgaaac taaaattaga
     4861 atgcctgaaa aaaataagga aactaaagca gaatatccct atgtatcaag ttatgggaat
     4921 gtaatcgaat taggagaagg agatctttca aagaacaaac cagacaattt aactaaaatg
     4981 gaatctggta aaatctattc tgattcagaa aaacaacaat atctgttaaa ggataacatc
     5041 attctaagaa aaggctatgc actaaaagtg actacctata atcctggaaa aacggatatg
     5101 ttagaaggaa atggagtcta tagcaaggaa gatatagcaa aaatacaaaa ggccaatcct
     5161 aatctaagag tcctttcaga aacaacaatt tatgctgata gtagaaatgt tgaagatgga
     5221 agaagtaccc aagctgtatt aatgtcggct ttggacggct ttaacattat aaggtatcaa
     5281 gtgtttacat ttaaaatgaa cgataaaggg gaagctatcg ataaagacgg aaatcttgtg
     5341 acagattctt ctaaacttgt attatttggt aaggatgata aagaatacac tggagaggat
     5401 aagtccaatg tagaagctat aaaagaagat ggctccatgt tatttattga taccaaacca
     5461 gtaaaccttt caatggataa gaactacttt aatccatcta aatctaataa aatttatgta
     5521 cgaaatccag aattttattt aagaggtaag atttctgata agggtggttt taactgggaa
     5581 ttgagagtta atgaatcggt tgtagataat tatttaatct acggagattt acacattgat
     5641 aacactagag attttaatat taagctgaat gttaaagacg gtgacatcat ggactgggga
     5701 atgaaagact ataaagcaaa cggatttcca gataaggtaa cagatatgga tggaaatgtt
     5761 tatcttcaaa ctggctatag cgatttgaat gctaaagcag ttggagtcca ctatcagttt
     5821 ttatatgata atgttaaacc cgaagtaaac attgatccta agggaaatac tagtatcgaa
     5881 tatgctgatg gaaaatctgt agtctttaac atcaatgata aaagaaataa tggattcgat
     5941 ggtgagattc aagaacaaca tatttatgta aatggaaaag aatatacatc atttgatgat
     6001 attaaacaaa taacagacaa gacactaaac attaagattg ttgtaaaaga ttttgcaaga
     6061 aatacaaccg taaaagaatt cattttaaat aaagatacgg gagaggtaag tgaattaaaa
     6121 cctcataggg taactgtgac cattcaaaat ggaaaagaaa tgagttcaac gatagtgtcg
     6181 gaagaagatt ttattttacc tgtttataag ggtgaattag aaaaaggata ccaatttgat
     6241 ggttgggaaa tttctggttt cgaaggtaaa aaagacgctg gctatgttat taatctatca
     6301 aaagatacct ttataaaacc tgtattcaag aaaatagagg agaaaaagga ggaagaaaat
     6361 aaacctactt ttgatgtatc gaaaaagaaa gataacccac aagtaaacca tagtcaatta
     6421 aatgaaagtc acagaaaaga ggatttacaa agagaagatc attcacaaaa atctgattca
     6481 actaaggatg ttacagctac agttcttgat aaaaacaata tcagtagtaa atcaactact
     6541 aacaatccta ataagttgcc aaaaactgga acagcaagcg gagcccagac actattagct
     6601 gccggaataa tgtttatagt aggaattttt cttggattga agaaaaaaaa tcaagattaa
     6661 gacaaaagct atagaaaaaa atggtttatg tactgagatt agatagtgag gtgatgacat
     6721 agttttgtga aaacggccat ttataactca attatttagt ttacttcact tcactattga
     6781 tactatttgg agttattaac ggacttagtt tagataacta atgaattgat tgaaagggtt
     6841 agtattgaca atattggtca tattgattag aaaatagagt ctatcaaaat ttaaaggcta
     6901 atagaggtga tgagacaatt tcaaggaatt aagtagcgtt tggttgctta attccttttt
     6961 atttggaagg aagtttttcg taaccgccca ataacgaagt ctattggacg gttacgatat
     7021 gatcactgac ttcgtcagtc ttatctacaa cctcaaaact gtgttttgag caacctgcgg
     7081 ctagcttcct agtttactct ttgattttca ttgagtatta gaacagaaaa aatgcttgga
     7141 gtatttgttt gtgtgtttat ttttatataa caaactataa acaaaacaaa aatataaaaa
     7201 aagagacaaa aaagaacaaa aagtaattga caacggtttc atatagtgtt atacttatgg
     7261 cataaagtta atggaaagaa gggaaaaact tatggtatta gattatttct ttgacaaaaa
     7321 ccttgtgttt tgcttagaag cggataatca agaacatctc tttgatcagg ttgcaacttt
     7381 attggaagaa cgagaaattg taactccaac ttatcgtgaa gccttgatca cgcgtgaaaa
     7441 gtcatttcca actggtttag atatggaatt tctaggaaag gacttgccaa atgtagcgat
     7501 tcctcacaca gatattgttc ataatctagc tgagaaagtg gtggttgttc gattagaaaa
     7561 accagtaact tttcacaata tgattgcgcc aggtaaggaa gtagaagtat ctctactctt
     7621 ctttatcatt aacaattcaa gttcaagtca aacgaacatt ctggctcagt tgatggactt
     7681 tttcacagga aatggtcatc ttgaagacct atcaaaaatt tctgaaccag aaaaacttta
     7741 tgcttacatt gctgaagcaa ccgcttaatc ttgtctatta aaaaataaaa tcggaggaaa
     7801 tccaaatgat taaaattctt gctgcctgcg gtgcaggtgt taactcaagt caccaaatta
     7861 aaagtgctct agaagaagaa ctttcaaacc gtggttatga tgttcactgt gatgcagtca
     7921 tggtgaaaga tgtaaacgaa gaccttatga aaggttacga tatctttaca ccaatcgctg
     7981 caacagacct tggttttgaa ccaggtatcc cagttatcga agctgggcca atcttattcc
     8041 gtatcccagc aatgagcgct ccagtatttg acaatattga agcagctatt aaagaacatg
     8101 gattaagcta attctaattt gttaacattc atataacata aaaaagggag gaactgttat
     8161 ggatgcaatc tttgacctaa tcggaaaggt tttcaatccc atcttagaaa tgggtggacc
     8221 tgtcatcatg ttgatcattt tgacagtatt ggctttactt tttggagtga aattctccaa
     8281 agcgcttgaa ggtggtatca aacttgccat cgctcttaca ggtatcggtg ctatcatcgg
     8341 tatgctaaat ggtgctttct cagcatcact tgcaaaattc gttgaaaaca ctggtatcca
     8401 attgagtatt acagacgttg gttgggcacc actcgcaaca atcacttggg gttctgcttg
     8461 gacactatac ttcttgctca tcatgttgat tgtcaacgta gtgatgcttg ctatgaagaa
     8521 aaccgataca cttgatgtcg atatctttga tatctggcac ttgtctatca caggtctctt
     8581 gattaaatgg tatgctgata acaatggtgt gagtcaaggg gtttcactct ttattgctac
     8641 agcagctatc gtccttgtcg gtgtgttgaa aattatcaac tctgacttga tgaaacctac
     8701 atttgatgac cttcttaacg ccccaagttc atcaccaatg acatcaactc acatgaacta
     8761 catgatgaac ccagttatca tggttttgga taagattttt gaaaaattct tcccaggcct
     8821 tgataaatat gactttgatg ctgctaaatt gaacaagaaa atcggtttct ggggatctaa
     8881 attcttcatc ggtttcatcc ttggtatcgt tatcggtatt atgggaactc cacatccaat
     8941 tgcaggtgtt gcagatgcag ataaatggcg tcttgttatc aaaggatggt tgtctcttgg
     9001 tttgactgcc ggtgtatctt tggaactctt ctcacttatc ggttcatggt tcatcgcagc
     9061 cgtagaacca ctatcacaag gtattacaaa cgttgctact aaacgtcttc gaggacgtaa
     9121 attcaatatc ggtcttgact ggccattcat cgctggtcgt gctgaaatct gggcttgtgc
     9181 caacgtactt gcaccaatca tgttgattga agcagtgctt ctttcaaaag ttggaaatgg
     9241 tatcttgcca cttgcaggta tcatcgctat gggtgttact ccagctctct tggttgtaac
     9301 tcgtggtaaa ttgctccgta tgattatctt cggaacactc ttgttgccac tcttccttct
     9361 ttcaggtaca cttattgcac catttgcaac agaacttgct aaaggtgtag gtgccttccc
     9421 agaaggtgtg agccaaactc aattgattac tcactctact cttgaaggac caatcgaaaa
     9481 acttcttggt tggacaattg gtaacactac aactggtgat atcaaagcaa tccttggtgc
     9541 agtagtcttc cttgtattct atatcggtat ctttgcttgg tacagaaaac aaatgatcaa
     9601 acgtaacgaa gagtacgcag caaaagcaaa ataatgcgct cctataaaat ataaactcaa
     9661 tgaaaatcaa agagcaaact aggaaactag ccgcaggttg ctaaaaacac agttttgagg
     9721 ttgtagataa
//
LOCUS       DBEJJV010000064         9045 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.064, whole genome shotgun sequence.
ACCESSION   DBEJJV010000064 DBEJJV010000000
VERSION     DBEJJV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 9045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9045
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.064"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..709
                     /locus_tag="ACL3GT_001990"
     CDS             <1..709
                     /locus_tag="ACL3GT_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR0517588.1"
                     /translation="IFIEHKGNYAYRRIHLELRNRGYLVNHKRVQGLMKVLNLQAKMR
                     QKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCYTDVTEFAIPASTQKLYLSPVLDGF
                     NSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHQFLEGKGI
                     QASMSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIK
                     VKLKGLSPVQYRTKSFG"
     gene            complement(837..1085)
                     /locus_tag="ACL3GT_001991"
     CDS             complement(837..1085)
                     /locus_tag="ACL3GT_001991"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0517589.1"
                     /translation="MASTSLQAPAKICFILIKLYSPYAFLSKYLGAILLSFFCYYAKE
                     IGCNNLTLSVWNDNEGALRFYQRQGMKPQETTMEMIID"
     gene            complement(1033..2115)
                     /locus_tag="ACL3GT_001992"
     CDS             complement(1033..2115)
                     /locus_tag="ACL3GT_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HGR0517590.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2241..3023)
                     /gene="gatD"
                     /locus_tag="ACL3GT_001993"
     CDS             complement(2241..3023)
                     /gene="gatD"
                     /locus_tag="ACL3GT_001993"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit GatD"
                     /protein_id="HGR0517591.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3023..4366)
                     /gene="murT"
                     /locus_tag="ACL3GT_001994"
     CDS             complement(3023..4366)
                     /gene="murT"
                     /locus_tag="ACL3GT_001994"
                     /EC_number="6.3.5.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016881 - acid-amino acid ligase activity
                     [Evidence IEA];
                     GO_function: GO:0140282 - carbon-nitrogen ligase activity
                     on lipid II [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HGR0517592.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4465..5781)
                     /locus_tag="ACL3GT_001995"
     CDS             complement(4465..5781)
                     /locus_tag="ACL3GT_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HGR0517593.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5974..7200
                     /locus_tag="ACL3GT_001996"
     CDS             5974..7200
                     /locus_tag="ACL3GT_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HGR0517594.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7399..8973
                     /locus_tag="ACL3GT_001997"
     CDS             7399..8973
                     /locus_tag="ACL3GT_001997"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HGR0517595.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRIEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2621 a         1745 c         1997 g         2682 t
ORIGIN      
        1 catttttatc gaacacaagg gaaattatgc ttatcgtcga attcatttag aactaagaaa
       61 tcgtggttat ctggtaaatc ataaaagagt tcaaggcttg atgaaagtac tcaatttaca
      121 agctaaaatg cgacagaaac gaaaatattc ttctcataaa ggagacgttg gtaagaaagc
      181 agagaatctc attcaaggcc aatttgaagg ctctaaaaca atggaacagt gctacacaga
      241 tgtgactgaa tttgccattc cagcaagtac tcaaaagctt tacttatcac cagttttaga
      301 tggctttaat agcgaaatta tcgcctataa tctttcaact tcacccaact tagaacaagt
      361 acaaacaatg ttggaacagg cattcacaga gaagcactac gagaatacga ttctccatag
      421 tgaccaaggc tggcaatatc aacacgattc ttatcatcag tttcttgagg gtaagggaat
      481 tcaagcatcc atgtcacgca agggaaacag ccaagacaac ggtatgatgg agtccttctt
      541 tgggattctg aaatcggaaa tgttttacgg ttatgagaag tcgtttcagt cgcttaagca
      601 attggaacaa gctattgtag actatattga ttactacaac aataaacgaa ttaaggtaaa
      661 actaaaagga cttagtcctg tgcaatacag aactaaatcc ttcggataaa ttaattgtct
      721 aactgtttgg gggcagtaca ttttaacact tgatactatg cgttttattg tgggaagatt
      781 ttcctcattt tctagtgaaa ttgaactttt tctaacatct tttgatagat gacttcttaa
      841 tcaattatca tttccattgt tgtttcttgg ggtttcatcc cttgtctttg ataaaagcgg
      901 agagcaccct cgttatcatt ccagacactt agggttagat tattgcagcc aatttcttta
      961 gcataatagc agaaaaatga caataaaata gcccctagat attttgaaag gaaagcatag
     1021 gggctatata gtttaatcaa aataaagcaa atctttgctg gtgcttgtaa agaggtcgaa
     1081 gccatccttg gtaacaacac cgcagtcttc aatacgaaca ccgactttac cagggatata
     1141 gatacctggt tcaacagaga agcacatgcc ttcttcgatg accatgtcgt ttccttccat
     1201 gatagatggg aattcatgga catccatacc gataccatgc ccgagacggt ggttgaagta
     1261 ctcaccataa ccagcttttt cgatgacctc acgggcagcg cggtccactt catgagcagt
     1321 cacacctggc ttgataaagt caagagcagc ttgttgggct tcaagagtca agttgtaaat
     1381 atctttcttg aattggtctg gtttgccgac agcgactgta cgagtcatat ctgacgcata
     1441 gccattgacc agaacaccca ggtcaaagag gagaagagca tcattttcaa ccttattagc
     1501 tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc aagaccatgg tatcaaagct
     1561 catttcataa ccttcacgtt tcatggcaaa gtcgatttgt gcgatgatat ctgtctcagt
     1621 cttatcaaga gaaatattgt caaaaccaac atgaacagcc ttgtcagcat aaagacctgc
     1681 aaccatcatt ttttgcactt catcagctga tttgatgagg cgcatgcgtt ggatacgagg
     1741 agtgaggttg tcaaactcag cagtctcaaa aactgttttc aaaccatggt atttggtcaa
     1801 gatgagattg tcaaactcaa cagcgacacg tttgaagtca agttgtggaa gagcatgttt
     1861 gattttttgc catggatttt cagaatcgac atagcccact actgggaagg aaacggtgct
     1921 acttgcacgt tctacttcaa gagctgggac aaagaggaga ggttcctgat ccgctaggac
     1981 aaagaggaac atttggcgtt catggggatc actgtaaaaa ccagtgaggt aattgattgt
     2041 gacggggtca gatacgacag cgacgtctag tttttctgat tcaagatatg ttaggatttg
     2101 ttgtaattta gacatatgct accttctttc tacccctcta ttttggcaaa aaatgagaga
     2161 aaatgcaagg gagaagggta aaagaaaaga caaaaaactc cgacaagata acggagttct
     2221 ttgatatcat tttcctttgt ttaagaaaag tcagccttgc ttttgacgtc actgtactct
     2281 tcagcgattt cttggctgag aatgtcctca taggcaggga gttggatgtc ctgaccatat
     2341 ttcttcttga gggcagtagt aactaggcga taagccagat tggcattacg agagaggata
     2401 ggcccgtgga agtaggaacc aaagacattc ttataatgaa ccccttcacc gaccttttct
     2461 tcgttgtttc catttccata gacaacctgt cccagcggtt tttggtcatc agagaggaag
     2521 gtacgacctt ggtgattttc aaatccatag taggtttcat cgaaatcttc attgtgaatc
     2581 ttgatgtcac cgataaaacg gttattggtc tggttgagcg tgtagtgtcc catgacccct
     2641 agcccttcga tacgttttcc tgaagcttca acataatatt gacccaatag ttggaaacca
     2701 ccgcagatag ccagaactac accgtcgttt tggatgtagt tgtcaatgct ctctttttta
     2761 gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt gaccaccacc gaaaaaggcg
     2821 atgtcgtagt gattttcatc aaagtcatca tggagagaaa cgatgtcaac ggtcacatgg
     2881 gctcccagtt tttcagccac atacttgagc atgaggatgt ttccattgtc cccgtaggta
     2941 ttcatgagat ttccgtagag gtgggcaatg ttgagctgat aggggtaatt gctatctttt
     3001 gaggaaagtg aagtataaac cattagttca tctcctttct aacaatctga cgactagcca
     3061 gcagttcacg aaattccagc atggcagtat aagttgccag aatataggca tgcttgcagt
     3121 cttgattctc aatggtcttg agaacttgct ccagattact cgtttcagtg attttctcag
     3181 ctggatagcc agtcactcgg aggcgacgag cgatttcaga atgacgaaca ccgccagcgt
     3241 tgatttcagg aatgtccatg tcagtgattt gctcaaagtc tgcatcccag atccagctag
     3301 tgtcaattcc atctgcatag ttggcattaa ggaggacaga taggctaaat ggataaggtg
     3361 ctagtttgat catttcgata gcttgggttg caccgactgg atttttaatc aagacaaggg
     3421 tacattcctt gtcaccgata tgaaaggttt cttggcgtcc aaagacagca cggctcttgt
     3481 caaatccctg tttgatgagt tgggaatctg cgccgaggaa acgggcgatg gccacagcag
     3541 ctagggcgtt atagatatta tagagcccgc cgatttggat accgtattct tggccgtcta
     3601 tgacaaagcg agagcgattg ttggtcaact caaccagttt tgtcaaacga tagtcgagat
     3661 caggacgttt acatccacaa ccttcacaga tataggcacc caagtttgca taggtattat
     3721 gctcatattt gaggatgcct tggcagtcag gacagagaat cccttcggta ttgtagtgag
     3781 caagttgggc tggtcctttt tccaagtcaa aaccaaaata ctctataggg tttggaatag
     3841 ttggcttgta gaaaagtgga ctgtctccgt taaggagaac agtagcagtt ggaacttttc
     3901 gaatggcatc caatatcatg ttataggtag tatagatttc accgaaacgg tccatctggt
     3961 cacggaagat attagtaatg acaaaaagac taggctggat atagtcacag atacgagata
     4021 gactggcttc gtcaatttcg aggacggcaa tatttttccc agtttttgaa gatttggctg
     4081 ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc gcttgggttg gttagaactt
     4141 gaccataaac ctcttttaaa atgccgacag tgagggcagt tgtcagggtt tttccatttg
     4201 ttccagtgac aacgacaatc tcgtagttct tagctaggct ttgtaaaata tctttatcaa
     4261 attgaagggc gactttccct gggagcgtac ttccacgtcc aagacggctt aaaacgaagt
     4321 gggaagaacg cccagcaaga aggcccaaag tagtttttaa gttcatgttt ctattatatc
     4381 acaaaagagg gaaaagacag atttggtgtt tcgtagaagt aaaaacagcc caaagagggc
     4441 tgtcagttaa gatgagattt caacttaaat cgcaaacaag tcattcaagt tctcagccaa
     4501 ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa ggaatcttgt tgtccatagc
     4561 aacagtaatg atgttgatga tttcttgaga accttctgag aagatgcttg caccaagaat
     4621 ttcttttgtt tcagtattaa caacagcttt gaaagctccg cgaaggtctc catttacgtg
     4681 accacgaggc atggctgcaa cagggatttc tttcactgcg tatggaagtt tcaaatcagc
     4741 tgcttggctt tcagtcaaac caacttgtga aagtgcaggt gtgatgaaca tagtatttgg
     4801 cacattgaga cggtcctcaa gtgtgtagct gccatctcca gcaaggtagc tgtaaacaac
     4861 acggaagtca tcaagtgaaa tgtaagtaaa ttgaaggcca ccgttgacat ctccaactgc
     4921 aaagacacca ggaacgtttg tttgacagtg tttgtctact ttaatagcac cacgttcagt
     4981 tagttcaata tctgtatttt caagttgaag tggttctaca tttggtttgc gtccagttgc
     5041 gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt acgacaagca cttggtcacc
     5101 atcgtttttg atttcagtag tatggatatt ttgaagcaat tcaatgccat cttcttccat
     5161 gtattgttta gcaagagctg cgatggaagg ttctgcacga ggtaggaatg tatccaaggc
     5221 atctaggact gtgaccttgc ttccaagttt gttgtaaagg ccggcaaatt caagaccgat
     5281 atttccgcca ccaaggattc caagtttttc aggtaatttg tccaagcttt ggatacctgt
     5341 tgagtcaaag atgtttttgc ttgtagcaag tccaggaatt ggcaagacgt ttgaaacagc
     5401 accagtgttg atgacgattg tttcagcagt cagttctttc ttttcatcac cagcttggat
     5461 ttcgatgact ttatttgaaa ggaagtgagc ttccgcatca aagatatcta cgcctgtacc
     5521 agcaacagtc gcatagtttt taccgttgag gcgaccagtg atcgtgtttt tagtagcaat
     5581 cacttcttca aaagacaagt ccttttcagc agcaactagc aaggttttag ttgggataca
     5641 accaatgttg atacaagttc caccgtacat agccttgctg cgttcaacga gggcaacttt
     5701 tttgccagct gaagccaatt tacctgctag tgttttacca gctttaccaa atccaataac
     5761 aattaaatcg tatgttaaca tttatcttcc tcctattcga atttcattct agcacaagaa
     5821 aaaaactttt gcacaattct gctacggaaa agacagaaaa agataaaaac gctttccaga
     5881 caaaaaacta gtaatttttt gacaagcttg ataaactaaa atcctatcta tttttatata
     5941 agaaagaata aatgttcgaa aataggaggt tttatgaaat cgaatcgtta tattattgcc
     6001 tttgctgggg tcattttaca cttaatgctg ggttcgactt atgcttggag tgtttatcgt
     6061 aaccctatta ttgaaaaaac gggatgggat caggcttctg ttgccttcgc ctttagtcta
     6121 gcaatctttt gtttgggctt atcggctgca tttatggggc gtttggtaga aaaatttggt
     6181 ccgaaagtca tggggagtct atctgctttt ctatacgcag gtggaaatat cttaacagga
     6241 tttgcaatag accgtcagga actgtggttg ttgtatctag cttatggcat tttaggtggg
     6301 cttggtttgg gagcaggcta tattacccct gtgtcaacga ttataaaatg gtttcctgat
     6361 aaacgtggtc tcgcaacagg tttagcgatt atggggtttg gttttgcttc tttattgact
     6421 agtcccatag cgcaacacct catcgcaggg gtagggattg tagaaacttt ttatatttta
     6481 ggagcaagtt actttattat catgctccta gcttcacaat tcattaagcg tccaaatgag
     6541 caagagcttg caattttatc ttcttcaggg aaagaaaaaa cagcctcttt gacgcaagga
     6601 atggctgcaa atcaggctct aaaaagcaat cggttttata tgctttggat tattttcttt
     6661 atcaacatag cttgtggttt aggcttaatt tcagcggcat cgccaatggc acaggagatg
     6721 gctggcttgt ctacaagtca tgcagcagta atggtgggtg ttttggggat tttcaatgga
     6781 tttggtcgct tgctctgggc gagtttgtct gactatatcg gtcgccctct aacctttagt
     6841 atattactgc ttgtcaatct tttcttttct ctctcacttt ggctctttac agattccgtt
     6901 ttatttgtag ttgctatgtc tattttgatg acttgctatg gagctggttt ttctttgatt
     6961 ccagcttatc tcagtgatat ttttggaacc aaggaattgg ccgctctgca tggttatatt
     7021 ttaacagctt gggcaatggc tggtttagcg ggacctattt tattagcaga gacttataaa
     7081 atggctcatt cgtacacaca aaccttgttc gtttttctca ttttatacag tatcgccttg
     7141 gctttgtctt attatctagg tcgttcaatc aaaaaagaaa gtcaaaaacc gcttacatga
     7201 ttttctgtag aaatggggct atcttttgct ctggtcttgt gttatactag ataggttgca
     7261 aagaaaacag tacttttctt ttgtggaaaa gaagcaacac gattttatat ctagttatat
     7321 gaaaatacgt cataaaaaga aaagtataaa ctaagcccta tagggtggct tcgcaccacc
     7381 tttagaaaga agaataacgt gaaatttaat gaattaaact tgtctgctga tttgctagca
     7441 gaaattgaaa aagctggttt tgtagaagct agtcctatcc aagaacaaac tattcctttg
     7501 gcccttgaag gcaaggatgt tatcggtcaa gctcagactg gtacaggaaa aactgcagcc
     7561 tttggcttgc ctacccttga aaaaatccgt atagaagaag cgactattca agccttggtc
     7621 atcgctccaa ctcgtgaact agctgtccaa agtcaagaag aactcttccg ctttggtcgt
     7681 agtaagggag tcaaagtccg ttcagtatat ggcggatcaa gcattgaaaa acaaattaag
     7741 gctcttaaat ctggtgccca tatcgtggtg ggaactccag gtcgcctctt ggacttgatt
     7801 aaacgcaagg ccttgaaatt acaagacatt gaaaccctta tccttgacga agcggatgaa
     7861 atgcttaaca tgggcttcct tgaagacatc gaagccatta tttcccgtgt acctgagaac
     7921 cgtcaaactt tgcttttctc agcaactatg ccagatgcca tcaaacgtat cggtgttcag
     7981 tttatgaaag cccctgaaca tgtcaagatt gcggctaagg aattgacaac agaattggtt
     8041 gaccagtact atatccgtgt taaggaacaa gaaaaatttg acaccatgac tcgtctcatg
     8101 gatgtggcac aaccagaact cgctattgta tttggtcgta ccaaacgccg tgtggatgaa
     8161 ttgactcgtg gtttgaaaat tcgtggcttc cgtgcagaag gaattcatgg cgacctagac
     8221 caaaacaaac gtcttcgtgt ccttcgtgac tttaaaaatg gcaatcttga tgttttggtt
     8281 gcgacagacg ttgcagcgcg tggtttggat atttcaggtg tgacccatgt ctacaactac
     8341 gatattccac aagatcctga gagttatgtt caccgtatcg gtcgtacagg tcgtgctggt
     8401 aagtcaggtc aatctattac ttttgttgct ccaaacgaaa tgggttacct tcaaatcatt
     8461 gaaaacttga ctaagaaacg catgaaaggt ctcaaacctg caagtgtaga agaatccttc
     8521 caatcaaaaa aacaggtagc tctcaagaaa atcgaacgtg attttgcaga tgaaaccatt
     8581 cgtgccaact ttgagaaatt tggtaaggat gctcgcaaat tggctgctga gtttactcca
     8641 gaagaattgg caatgtatat cttgagtctg acagtccaag acccagatag ccttccagaa
     8701 gtggagattg cacgtgaaaa accactaccg tttaaaccat caggtaatgg tttcggtggt
     8761 aaagctaagg gaggtcgtgg aggccgtcgt ggggacgacc gtcgagagcg tgatcgtcgt
     8821 ggcaatggtc gccgtgatga gttcaaaaaa ggaagtcgtg gcaacgatcg ttttgataag
     8881 gaaaaacgtt accgtaagga taataaaaaa ccacgcaata ctttaagcga aaagcaaaca
     8941 ggctttgtta ttcgtaacaa aggtgataaa taagaaaaag cggttcaaaa tgaatcgctt
     9001 ttttatataa ggagaccgaa tgtgaaaaag acaaataaaa ttatt
//
LOCUS       DBEJJV010000065         8370 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.065, whole genome shotgun sequence.
ACCESSION   DBEJJV010000065 DBEJJV010000000
VERSION     DBEJJV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 8370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8370
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.065"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(627..935)
                     /locus_tag="ACL3GT_001998"
     CDS             complement(627..935)
                     /locus_tag="ACL3GT_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HGR0517596.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(932..1240)
                     /locus_tag="ACL3GT_001999"
     CDS             complement(932..1240)
                     /locus_tag="ACL3GT_001999"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HGR0517597.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1245..2540)
                     /locus_tag="ACL3GT_002000"
     CDS             complement(1245..2540)
                     /locus_tag="ACL3GT_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HGR0517598.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVNRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2558..3967)
                     /locus_tag="ACL3GT_002001"
     CDS             complement(2558..3967)
                     /locus_tag="ACL3GT_002001"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HGR0517599.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKSIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4125..4853
                     /locus_tag="ACL3GT_002002"
     CDS             4125..4853
                     /locus_tag="ACL3GT_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HGR0517600.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5313..5507
                     /locus_tag="ACL3GT_002003"
     CDS             5313..5507
                     /locus_tag="ACL3GT_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HGR0517601.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5629..5795)
                     /locus_tag="ACL3GT_002004"
                     /pseudo
     CDS             complement(5629..5795)
                     /locus_tag="ACL3GT_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558122.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5873..7183)
                     /locus_tag="ACL3GT_002005"
     CDS             complement(5873..7183)
                     /locus_tag="ACL3GT_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HGR0517602.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7420..8292
                     /gene="nadC"
                     /locus_tag="ACL3GT_002006"
     CDS             7420..8292
                     /gene="nadC"
                     /locus_tag="ACL3GT_002006"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HGR0517603.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2604 a         1464 c         1588 g         2714 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaact agaaaacgag tgccattcag ctcaaaacac
      121 tgatttgaga ttgcagataa gactagcccc ctcattaaca gatttacgat aaaacgatga
      181 caaggtgtgt tgctttttga tttctaaaga gtataatgat agatctctat aaaataagtg
      241 cgaaggaaat gagcttttat agtcctttcg ttttaaaata ctatctcaga tattcttata
      301 tcgacaagaa gtttttgagt cattccctca tcatacatat taaataaata gtggctcatt
      361 caatttttca ctagaataat aagctagtat agtaaactga aataagatat aaacaaataa
      421 attggagctt aacatccatt tccagcaatt ttttagaaac tacagtggac tattctagat
      481 tcaacatatt ataaaaacta gagtaaaaga aaaggattgg atcttgtgta atgcaggatc
      541 caatcctttc aatcattttg tccaactttt ggaggttcct acaatgtagt cgtcattaat
      601 aaagacagat gggaatgaca gtgttcctat ttattttgat agagatcgat gaattcttta
      661 gatagcaact gaataatctc tgttgaagcc atttggtctt ctgcatgcat aaatagcaag
      721 gagaatccta ttttttctcc agtagcttct ttttgtatga gattagagtg aatcttgtgc
      781 gcttctacta aggagtcttc cgcttcttca actttaattt tcgcttcttt taaatttcct
      841 gccttagcta gttggatggc ttcaataaag gatgatttgg ctgctccact attggcaatg
      901 agctgaaaac agatatattc catttcttct gtcatcttat ttctcctatc catgcaagtg
      961 cttgttccag aacttttgct ccattcatca ttccgtaatc ccgcatatca atggtatcta
     1021 cagggatatt tcctgcaatt tctttcacag caagtaactc ataacgaatt tgtggcccaa
     1081 ttagaatgac atctgcttca tggatattct ttttagcttc tgtcattgat tttgcttgga
     1141 tagagatttc aatcccacgt tcagtcgcac tttgttgcat ttttttaaca agcatacttg
     1201 tcgacattcc cgcattacat actaataaaa tttgtttcat aatcttaacc ttccatttct
     1261 tgttcaacaa ctttgtcatt aactttgata aatggaatgt atagaagaac tccaagtgca
     1321 aagatgatga attgaactag aactgctctc acgtcccctg ctgttgctaa ccatgcattt
     1381 aagaatactg gtgtagtcca aggaacttgt ataaatgcag gactcatgaa tcctgtaact
     1441 gttgctaagt agctgattaa aataccaagg actggaactg tgataaatgg aatagctaat
     1501 gaaatgttat aaacgattgg gtaaccgaat aatactggtt cattgatatt gaagatacca
     1561 ggtccaaaag ataatttagc cacgttttta gagacagcat tgcgactcac taagaatgtt
     1621 gctattaata aacataatgt agatccacta ccacccatta aagcgaatgt ttgtatttgt
     1681 gataggttga tgatgtgtgg aatggcttgt ccattatttg ctgcagtgat gttttcagta
     1741 atgttaatta atagtaatgg ttctaggatg gcactgtaaa taactgcttg gtgaatacca
     1801 aatagccata acatatttcc taaagagtaa ataataatga ccccgattaa gcttgtacca
     1861 atatgacgaa ttggttcttg aataaagatt gtaatgattg agattaagtt cattccagtt
     1921 atattgaata ataatgctga aacaacccca aataaggaga tgacggtcat gactggaagt
     1981 aatacgctaa atgatctatt aacagctggt ggaatatttt caccaaggtt catttgtaaa
     2041 gctttaacat ttgataattc aatgaataat tctgttgcaa taatcgctac gataaccccg
     2101 gcgaacattg cgcctgtacc tgtgttgttg aatgaaagaa cacctgaaat gtttacagca
     2161 tcttttgctc cgtcaggaac tacagaaact gtatttggca tcatcacaat taaagaaact
     2221 aatgatagca ttgatgctgc taacgggttt tcgaaatctc tgtttttagc taagaaataa
     2281 ccaaccatta cagcaataat catacctgaa atacttaaag taccgtttgc aattgttatt
     2341 ccccaatatt ggaatcttgt taatgtatcc ccttggaaaa tccacttaaa taccgtgttg
     2401 ttcaaaagaa cgattaaacc tgccaaaata tataatggca ttactgttac gaatgcatct
     2461 cttagggttt ttaaatgaat ttggttccct agtttaccag caaaggtggc aaattggtct
     2521 ataaattttg agtttttcat atgaatatct cctctcttta ctcctcaatt tctacttcaa
     2581 aaccgttatt gtcacttact ttgcgatacc atcttcctga gctcttgatg gttctctttt
     2641 gcgtttctaa atcaacggag ataaatccgt aacgattctt atatgcatta ttccaagacc
     2701 agcaatcaaa tgcggtccaa gcgtggtatc caaaacagtg acttccctct tcaatggctt
     2761 tatgtagcca tcttaaatgt tcttcataaa attcaatacg atacacgtca tcgataactc
     2821 cattttcatc gataaaccgt gcttcgtttt caacacccat tccgttttca ctgataaacc
     2881 atgggatatt accatattct tccttcacaa tcatagcaat atcataaatg gatttcggaa
     2941 aaatttccca accacgatat ggattcatgc gacgctccgg ccattcatac tctttgaagt
     3001 attggtctgg catccagggc gtctgatatt cctcaggatt tgcttgtgct tgaacacgtt
     3061 ttggatggta gtagtttact ccaagaaaat caaccgtatt tgatttcatc agttgaagct
     3121 ctttttcggt atgactccat aacacgccat ctctctctag ctgttttacc aatctttctg
     3181 ggaaagttcc tttaacagct ggattcaaga agactttgtt aaagaagtca tctgtaaatc
     3241 gacttgcttc taagtcttct ggagaattac ttcttggata agcaggtgtc aagtttaaaa
     3301 taatcccaat ctttccatca agttctaatg agcgatatag ttgaatcact tttgcactag
     3361 caaggtttag attatagatg acttgtacgg cctcttttcc ctttcctttt agatttggat
     3421 aatggaaagc atataagtat cctgcttctg gaatgaccat tggctcattg aaagttgtcc
     3481 agtaatgaac cttatctcca aagcatgtga aagcagtctt ggcaaacttc acgaataact
     3541 ccactacatg tttgctttcc caaccaccgt atttttgaag aagttccact ggtaaatcaa
     3601 aatgatgtaa attcatcaca agatccatct ggttcttttt agcttcttca atgatggcat
     3661 tgtagaaagc aatacctttt ggatcaggct cacctgtctc taaattcttg atgagtcgac
     3721 tccattggat ggaagtgcgg aaagaattaa ctccaatttc cttcatcaag tggaaatctt
     3781 cggtgtaagt atgaaaaaag ttactggcta caagaggtcc gacattatcg aaaaaatctt
     3841 ctggatgcgt tttgaaccag tagtccatca cattttcatg tacttttcca tattgacctt
     3901 ctgtctgagg tccgctagaa gctgctcccc accaaaacag attaggaaat actaactttt
     3961 ttttcatgct caacctcctt tctattattc tatacataaa gtatagcata attttaaaat
     4021 ttgtctagac atttttaaaa attgttgata catatcttgt gtttgcctca tttcttgaac
     4081 tttgttatac tactattaga atattataga gagaaccaga ttaaatgagt acaaaatatt
     4141 tatttattta caatgagatt cgtgaaaaga ttctttgtaa taaatatacc atgaacgaac
     4201 aattacctga tgaaatgaca ttagctaaac agtttgcctg tagtcgaatg acgatcaaaa
     4261 aagctttaga cttgttagtt tctgagggct taatttttag aaaacgtggg cagggaacct
     4321 ttgttctctc tcgtggcagc tcaaaaagaa aattaatcgt tccagaaaga gatatccggg
     4381 gactgacaaa aatatctgaa gatgctcatt ctacaattga ctcgaggatt attcacttca
     4441 aattagaatt tgcaaatgaa tttttagcag aaaaactaca ggtcgctttg cagagtccag
     4501 tttataatat ttaccgcctg cgtattattg acggtaaacc ttatgttctg gaacaaactt
     4561 atatgagtac cgatgttatt ccaggtatta ctgaagatat tttacaaaaa tcgatttaca
     4621 attacattga aggaaagtta ggattgcata ttgccagtgc tacaaaaatc ttacgagctt
     4681 cttctagttc agaaaatgag caacattact tgcagctcct tccaacggaa ccggtatttg
     4741 aagtagaaca agtggcttat ttggataacg gaactccgtt tgagtactcg attagtcgtc
     4801 atcgctatga tttatttgaa tttaattctt ttgcattacg acattcctcc taggagaaaa
     4861 tgtgaaaatg aagccaatct tttacagact ctagtttaag aaaaatttaa aacagggcaa
     4921 gaaggtccca tctatgctta aatggtttct cttttctaaa taagatggct ttaaaagagt
     4981 gatcgtttta tccatcatgt tgaaaaatat cttcgtatag cttatagagt aggtactgaa
     5041 attgttcacc tgatctactt cttatagtta tttagtttta aatagtgttt caaatattct
     5101 tacactgacg agaagttttt gagtcttttc ttgtaacaca tatagtatac tgaggttaga
     5161 atagtagact gtgacttcta acaaattgct agaaatgaat ttcaatctcc caatttattt
     5221 gttcaaatat tgttttaata tattgaataa attctgaatc ataatcattt aaaaaaattt
     5281 tattttttta tttttcatta cgaataatat agatgaaggg gaaagagtat gaaaacagaa
     5341 ctgtttcttt tgctattagt tcaaaaggag aaaaaatgaa agtagaaaat atttcgtata
     5401 gggtggatca tcgtatattg tttgataata tttcttttga tacttcgagt tcaggcgtga
     5461 cattaattac tggtaaaaat ggtacaggaa agtcaacttt actatagtag attgaaacta
     5521 gaatagtaca catctacttc taaaatattg ttagaaatcg atttgactat cctgatctat
     5581 ttgtcctgtt cttatttcat ttcactatat ctcaaattga gtatgacgaa gtgcgctccc
     5641 atgtcctggg aacgcacttt cttcatattt ttcatattct tgaatccatc gataaagact
     5701 attgggatga atttttaaag ttgaactaat catttttaca ggatgagatt tacagcagag
     5761 agtttgaagg ctttatcaaa ggtttttctt ggcataatga cttttcctcg tttccactta
     5821 attttgtgtc tactttatta taccaagtcc acccttaagt tagataataa atctaactta
     5881 aggaagctag aaggatgaga atccaggtgg tcaagagtcc caaacttaag ctgatgggga
     5941 cacccagaat aatttgcttt ttgaaggcaa ggccacgttc ctctatattg ggaagtgaga
     6001 gttgaatgag agaaccagct gatgaaaagg gtgagatatt agtagataga gcgccaataa
     6061 cggtggctgt tgtgagtaag tgaatatcaa tctgaggatt ttgagcactg atgatagcaa
     6121 tgatgggaaa gagggctgga gctacaacgg atagggtgga actaaagagt gacatcactc
     6181 cggctatcac acaaaagaac agaggtaacc agaaatgagg aatggttgtt gtcatgaggt
     6241 gccctatcag tgtgactaaa cctgacttga ccgctagaga cattagtaag ctcatgccgc
     6301 agagcatgat aattgtagcc cagggaacct tagctaaaat ggcttcttgc ttccctaatt
     6361 tgagccttaa ggcgaggcag accatgagta ttgagacaaa gccaatatca aatgtttttt
     6421 gataagtagc tatccaggcg atgtttggga aaatgagatg caacaaggga aaaagccaaa
     6481 ccaaaaccat gctgctgatc atgagcaagg tggtttgtct ttgaaccttg ctgaggagtg
     6541 gtggttggtc aatagtcaag gatgagtttg ttcttccctt actatagtga ctgtaacagg
     6601 ataataaaag caagacgatg agtgggtaga taatgctgac gataaagata tgattgccaa
     6661 gtgaaaaagc ttgctcttcc catcccattt gcttaaacag gccttgaaag acaatgcctg
     6721 agctactggt tatcaaatta gcccctcctg aagctcccca attgacggct tgagctccaa
     6781 tcaaagggtg tttgtccgct ttttgacaga gggtaatcgc tagaggacag caaacggcca
     6841 tagtagtgaa aaatccagca cctaaagcag acaaaagggt tgccatcagg tataaaatca
     6901 tgtagagggc gttagggtgg gtgcgtgtgc ggtagagaat gtgttgagcc aaaacatcaa
     6961 gagtaccgtt agttgttgca acgttataaa agagagagac gctaaaaatg gtaaaaaaga
     7021 gtgaggttgg ccaaaaatga agaagttctt tggggcttaa tcccatgaga gtggttgcga
     7081 tgaggtaaga aaaagcaata gccagcaggc caatattgat tttggtgcgg taaccaattc
     7141 caatggctag agcaatggcg ctaatcatta ttaaatgaat cattgaattg tcctttcagt
     7201 tagaatatgg aaataggttg gcaattttgg cgctcaaaag accacctgtt tcctattggt
     7261 acttgactat tatacacaaa aaaaatacaa ttgtcttgac aattgtattg acacttgtta
     7321 gaattaaaaa tgaggtattc aggcttgtga tttcctatgg aagttaatag taattgcctc
     7381 tagtgcttac aagtgatatt aaaaatagag gacttagtga tgtcaatcat ttcaactgat
     7441 ttaacccctt ttcaaataga tgatacattg aaagcagcct tgcgagaaga tgttcattcc
     7501 gaagattaca gtaccaatgc catttttgat catcatggcc aagccaaggt gtcgcttttt
     7561 gccaaggaag ctggtgtttt agcgggacta accgtttttc aaagggtttt taccctattt
     7621 gatgccgagg tgaccttcca gaatcctcat caatttaagg atggggatcg tttgactagt
     7681 ggcgatttgg ttttagaaat cataggctcg gtgagaagtc tcttaacatg tgaacgcgtt
     7741 gccttgaatt ttttacaaca tttatcaggg attgcttcga tgacagctgc ttatgtagaa
     7801 gccttaggcg atgattgcat taaggtattt gatactcgaa aaactactcc taatttacgt
     7861 ctttttgaga aatatgccgt gagagttggc ggtggctata atcatcgctt taatttatca
     7921 gatgctatca tgctaaaaga caatcacatt gcggcagtag gtagtgttca gaaggcaatt
     7981 gctcaagcgc gtgcctatgc cccttttgtg aaaatggtcg aggtggaagt ggaaagcctt
     8041 gctgctgccg aagaagctgc ggcggcgggt gctgatatta tcatgttgga taatatgtca
     8101 ttggaacaga ttgaacaggc cattacccta attgcaggac gttctcggat tgaatgttct
     8161 ggaaatattg atatgaccac tattagccgt tttcgtggtt tagcgattga ttacgtctcc
     8221 agtggtagtt taacccatag tgctaagagt cttgattttt ccatgaaggg tttaacctac
     8281 cttgatgtct aagttgtaaa ataaactaac tttttaaagg atgtctttcc tctagaacga
     8341 gttttatgtc agatagttta aacgcctctt
//
LOCUS       DBEJJV010000066         7892 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.066, whole genome shotgun sequence.
ACCESSION   DBEJJV010000066 DBEJJV010000000
VERSION     DBEJJV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 7892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.066"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            10..1059
                     /locus_tag="ACL3GT_002007"
     CDS             10..1059
                     /locus_tag="ACL3GT_002007"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0517604.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAYG
                     GNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLVF
                     LLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVALVDKSQFACE
                     IAIKVWRNSLKFSII"
     gene            1089..4439
                     /locus_tag="ACL3GT_002008"
     CDS             1089..4439
                     /locus_tag="ACL3GT_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HGR0517605.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSLLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            complement(4945..5415)
                     /locus_tag="ACL3GT_002009"
     CDS             complement(4945..5415)
                     /locus_tag="ACL3GT_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HGR0517606.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(5432..7705)
                     /locus_tag="ACL3GT_002010"
     CDS             complement(5432..7705)
                     /locus_tag="ACL3GT_002010"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HGR0517607.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         2473 a         1284 c         1684 g         2451 t
ORIGIN      
        1 ggtggttgca tgaagaaagt gaaattaggg caagtggcta cttttatcaa tggctatgct
       61 tttaaacctc aagattggtc atctgaaggg aaagagatta tcagaataca gaatctgact
      121 aaaacttcaa aagggataaa ttattattcg ggtacgattg ataaaaaata cattgttgaa
      181 gctggtgata ttcttatttc gtggtcgggt acattagggg tttttcagtg gtgtggaaga
      241 tccgcagtat taaatcagca catttttaaa gtggtttttg ataagataga tatagataaa
      301 tcgtatttta aatatgttgt tgaaaaaggt ttacaagatg ctgtaaaaca tactcatggt
      361 tccacaatga aacatttaac taaaaaatat tttgataata ttatagttcc atatacaaat
      421 ttgggagagc aacaaagaat tgcaagtgag ctggatttgt taagcaagct gattttaagg
      481 agacaagaac aacttgaaga gcttaatcta cttgtaaaat cccgatttaa cgagatgttt
      541 ggggatcctt taaataataa caagaaattt gcagtaaaaa cgggacaaca gtgttttaaa
      601 ttttcaagtg gaaaatttct tgataaacat gatagagttt ttgaaggtta tcctgcctat
      661 ggtggaaatg gcattgcttg gaaaagtcga aaatatttaa ttgataatcc tactatcatc
      721 attggtcgtg taggtgcata ttgtggtaat gtaagaacta cccacggtaa ggtatggata
      781 agtgacaatg ctatatatat aaaagaattt aagaattccg atttcaatct tgtattttta
      841 ttagaattaa tgaaagtaat tgattttagt aaatttgctg atttctcagg tcaaccaaag
      901 ataactcaaa aaccattaga aaatcagaaa tatatcctcc cccctctagc cctccaaaat
      961 gagttcgcag actttgtagc cctggtcgac aaatcacaat ttgcttgtga gatagctata
     1021 aaagtgtgga gaaatagctt gaaatttagt ataatatagc taaactattt gtttaaagtg
     1081 agaaaaaaat gggaaatttt agctttcttt taaaaaatga cgaatatgaa tctttttcaa
     1141 aaccttgcat tgaagctgag aatatgattg ctacatcaac tgtggctact gcctttatgg
     1201 cgcgtcgtgc tttagagcag gctgtccatt ggatatatag tcacgattca tatttagaag
     1261 ctccctatcg tgctactcta tcttctttag tatgggatga tgattttagg gatatcgtag
     1321 attctgaact ccacaagcag atagttctgt tgattcggtg gggaaaccat gctgctcatg
     1381 gtggtgaaat taaggaacga gaagcgattt tagctttgca tcatttgtat cagtttgtta
     1441 attttatcga ttattgttac agcaatgagt ttgtggagcg ttattttgat gagaagtgct
     1501 taccactttc agcaaacatc aaataccgag aaactccaca atctatgata aagttacaag
     1561 acagtttacc agaactgcct gattttcatg aacagatggc tgctcagtcc gtagaagttc
     1621 aagagactta tactgaaaaa cgtgagactg cagcgcaacg gcaagatgtg cctttccata
     1681 ttgatcaatt atctgaggca gagacaagaa agctctttat tgatatcgat ctccgtttag
     1741 caggatggat atttgaagaa aactgtcgtg ttgagatagc cgttgatggt ctcaagcacg
     1801 gttcaggaat tggttactgt gactatgtac tttatggtaa aaatgggaaa attttagcga
     1861 ttgtagaggc taaaaaagcc tctgtcaatc cagaagtagg ggaagtacag gtcaaagaat
     1921 atgctgaagc tcttgagaaa catatcggct atcagccaat ttgctttatt acaaatggct
     1981 tgaagcacta tatacttgat ggtccgaacc gccgccagat tgcaggcttt tactctcaag
     2041 aagaattgca attagtgatg gatagacgtc atcttcaaaa accacttgag gatatttcta
     2101 gtaaaattag ggacgatatt tccgggcgtc actaccaaaa acatgccatt gcaagcgttt
     2161 gtgaagcttt ctctaatcat cgtagacagg cacttttggt tatggcaact ggggctggga
     2221 aaactcgtac agcagtttct ctagttgata tcttatcacg tcataactgg gtaaaaaacg
     2281 ttctcttctt agccgataga acttccttgg ttaagcaagc ctatgattcg tttagaaaat
     2341 tactcccaga tctttccgtt tgtaacttct tagaagataa agaaggagct caatcaagtc
     2401 gcatggtctt ttcaacttat ccgaccatga ttggagcgat tagtggtcaa gaagaagtaa
     2461 atcaacgccc tttcactgtt gggcattttg accttatcat aattgacgaa tctcaccgtt
     2521 ctatttatca gaaatacaag tccatttttg attattttga tgcaagaatt gtaggcttaa
     2581 cagctactcc gcgtcaagat ttagataaaa acacctatgg attctttaat ttggagaatg
     2641 gggttccaac atatgcatat gatttggaag aggctgttaa agacggatat ttagtagcct
     2701 atcattctat cgaaaccaaa ctgaaactac ctacggatgg tctacattat gatgatttgt
     2761 ccgaagaaga aaaggaacat tttgatagca aatttgaaga cgatagctgt gaaaaagata
     2821 ttgatgggag tgtatttaat tcctttgttt tcaataaaag tacagtagaa attgttttaa
     2881 atgaactcat gacaagagga attcagacag cctcgggtga tgaaattggt aaaactatta
     2941 tttttgctaa aaatcatgat catgcggaat atatcagagg tatttttaac aaccgctatc
     3001 ctgaaaaagg gagcgactat gctcaggtga ttgattatag tattaagcat tatcagacct
     3061 tgattgatga ttttaaaatt aaggagaagt atcctcaaat tgcgatttct gtcgatatgt
     3121 tagatacagg tattgatgta ccagaggttg ttaatttagt cttcttcaag aaagtacgct
     3181 ctaaaactaa gttttggcag atgattggtc gaggaacccg tctatgtaaa gatttatttg
     3241 gacctgagca ggataaggaa aacttcttgg tatttgatta tggggacaat tttgattatt
     3301 ttcgtgcaga tccaagagat ggagagggtc gtcacattgt ttcgttgact cagcgtttat
     3361 ttaatatcaa agtggacttg attcgagaac ttcagggact ccaataccaa gaagatcagt
     3421 ttgcgagagc ataccgtcag cagcttgtct cggaacttca aggtcgtata gagagcttaa
     3481 atgagttgga cttcagggtt cgtatggttt tagatacagt ttatagctat aggaaattgg
     3541 aaagttggca gaatctaact gctgttacaa gtgaaaccat tcaaaaaaat ctctctctgc
     3601 ttttatttga tgaagataaa gaagatgaga tggcgaggag atttgatttg tggttgcttc
     3661 atattcagtt ggggcaactg acagctaaat cttccactgt tcatatttcc caagtgatga
     3721 agacggctag agctctttct gctattggca atatcccgca ggtttttgag caggctgaaa
     3781 ttatcaggaa agtacaggag cctgaatttt ggaaagaagt taacttgtct gatttggaaa
     3841 aaattcgtct tgctattcga gatttattac agtttttgga taaaacagac cgtaaaccct
     3901 actatgttaa ctttgaagat cgtatactct ccactgttca cgagaccaca gcatttttgc
     3961 aggtcaacga tcttcggtct tacaatgaaa aagttgagca ttatttgaaa actcatctgg
     4021 atgaggagtc catttctaag ctataccata ataaaaagtt gacatctgat gatatgcttg
     4081 cacttgaaaa attgctttgg gaaaaattag gtagtaaagc agactaccaa agtcattatg
     4141 aaaataaggc aattccgaga ttggttcgtg agattattgg cttagataga gagtctgcca
     4201 atcgtatttt ttctaaattt ttgtcggatg agaatcttaa tgccaggcag atttcatttg
     4261 taaaattgat tgtagactac attgtagaaa atggtttttt agagacgaaa gtgttaacgc
     4321 aagagccgtt taaatcttat ggttctgttc aactactctt ccaacaccaa ctaccagtac
     4381 ttcgtaatat tgttcaaatc attgaactta tcaataatcg agctggagaa gcggcttaaa
     4441 ttctaaagtg attgccatgc tgagactcat ttaaaattaa aaagagtaga aatttatgct
     4501 atatatgaga agttttatta ggaagaatgt catcgttttc ctagaataca gtatcagttg
     4561 ttaagtggtt gataaatttc aaagtagata cttgtaccac gatgtttgtt gatcgagtta
     4621 ttaacaaaag agctactttg attttaaaga aatagaaaac aaaaagccga gcaagaattc
     4681 aattgcagga gaaaatgaaa taatactcaa tgaaaatcaa agagcaaact aggaaactag
     4741 ctgcaggctg ctcaaaacac tgttttgagg ttgtagatgg aagctgacgc ggattgaaga
     4801 gattttcgaa gagtataaat cttcctagga taaagcaaaa cgcatagtat caagggtttt
     4861 caacacttga tactatgcgt tttctgatgt taaagacttt ctaccaggtt ttttaaaagc
     4921 ataattgtta gttgtagtca tttattattc ttcaaagaaa aatggtgggg cgaatttttt
     4981 cagttcttca aagcactttt gagcagtatc tgcatcttca cagatgataa gacagacatc
     5041 attaccacaa agggtagcga tagcgtcagg gaagctcaaa gtatcaatga tagaaccaaa
     5101 ggattgagcc agtccaggaa gggtttttag taggacttgg tgttgaactg ggcgcatcca
     5161 gacaagggcg tcttccatgt agagttcgag acgtttttcc cattttgaga tggaaccatt
     5221 gttaagaaca taataagcgc tatcttcttc gcggactttt gataggttca tatttttgat
     5281 gtcgcgtgag agggttgcct gggttacttg aatgtcgttc tcagcaagaa gggcttgcaa
     5341 ctcagcctgt gtatgaatct tgttttttgt gataagagcg cgtataagtt ggtggcggtg
     5401 ttctgattta ttcataataa tgtaactcct tttagcaagg taaggtaagc atggactgag
     5461 cgaggtcgac agtcaagtgg tagtctgtat tgtcacggat ggtgatttca aagtcagtag
     5521 tatagaggac taaacggaga gtgtctcctt cttttagctt gtaaatagtt ggctgcagtt
     5581 caaattgaac gtccatccat tcatctgcag taatatcctc tactaacagt aaatcatttc
     5641 tattttgtaa attaaggtaa ccttttgtca cgactcgttg tgcctctggt ctaaatggca
     5701 attcacagag attttccaac atgtgatagc gaccgttgtc aatggttcta gcacttaaaa
     5761 tagctggata aggttgtagg tatttctttt gcccaaattc tagcagttgg gcagataaga
     5821 gccccttgtt tgtactggat ttgatacgaa gattgagctg agcgcgaccg tttaggtgga
     5881 gatctttagt cacaggaagg ttaatagtaa tctgattggc tttcccttga tagagctctg
     5941 tattgaaggt ttggtatgtc ttaccatagc gctcaaaatc cttatctggg tactggtttt
     6001 gaatagcttg ctcttcttga ccaagtgaga aggtttcaca gttttcttgc ccaccgaagt
     6061 tatcaagtga taaccaagtc tgtggagctg tattgtcctg ccagataaca gtaggaagtt
     6121 gaaagtctgt ttcctgtcct agtaatttct tggtcaataa ggcatttatg gactcacgga
     6181 agtcaattga ttgccaattg ttcatgtaaa catgggcacc attatggaaa aagagatgct
     6241 tgtgtatatg agtaggaaga gcatggaaca tctggtaaac atgaagtggt ttgacattcc
     6301 aatcctgaga accatgagta aagacaacct ctgcctttac tttatgggca ttgagcagat
     6361 aattgcggtc atgccaaaac tgattgtagt ccccagtttt tcggtctagc tgagctttca
     6421 ctttttctaa gtcagcttgg tgagcttcat tgccacggat atagtcgcca gctaagagat
     6481 tacgagaata ggttaactca gcaagggagt caaagtcctc acctggataa ccacctgggc
     6541 tagtcaccag accgttttca cggtagtagt tgtaccatga tgaaattcct gcctcggcaa
     6601 tgataacttc taaaccatcg actcctgtag tcgcaagacc attggacatg gtacctagat
     6661 aggaaagtcc tgttgtagca acttttccgt ttgaccaatc agccttgact tgacgctggc
     6721 gcgtgtgatc agtaaaggca cggcaacggc cgttaagcca atcgatgaca tttttataag
     6781 cctcgatttg ctggtagtct ccattagtca tgaaacctgt cgagtctttg gtaccaacac
     6841 ctgagacata gagattggca aagcctctcg gaaggaagta gtcgtttagt gtatagctag
     6901 agttgatgtg agttagcttt tcctcagcct ctgctataag ctcagcttta ccttggggtt
     6961 ggacgagatt tagttgaggt ttctctagct caatcttgtg aggaagttta acctcaagct
     7021 cgccctccat cttgtagaga gccttgtcac tagccttgtc attggttccc tgatgataag
     7081 ggctggctgt catgatggca gggatttttc catcaaaacg agggcgaata atgctaacct
     7141 ttactaggtc tgatagccct ttttggtcag tatcgacacg agactcaacg taaacgactt
     7201 cacgaatgac atcctggtta gaaaaagtag ccaaactctt gccgttaaag tagtggtagt
     7261 cattatcctc cggaataaga ccatcactaa caagttggtc gataagagta tttccttttt
     7321 tggtgcgagt attgagtaac tgatagagat tttcaatcaa gtcaccatat ataatgggaa
     7381 atccagtttc tttacgaaaa acgtcactat cttcgaagtc aaccaaataa gaaaagccta
     7441 aaagttgaaa agcaacagta taaaaaatat ctgctgtcag ttcatcttct gattgaaaaa
     7501 atgtcagcag gtctgttttt ttatcagctg ctaggataga aagtgggtag ttggtgtctt
     7561 gataagtgaa aaagaaacga cgtaaaaagg tttcaagtga gtctttgtga ttggctgtat
     7621 tttgtaaatc aaagccacat ttttttagtt cagataagac attttctttt ggaaaattga
     7681 tataactata ttgattaaaa cgcatagaac ctccatatag aatgacagtt aaggttatta
     7741 tatcaaaaaa aaagcagaaa gggaattgtt aacttcaaaa ggaaataatc caataaaaat
     7801 gaataaagta ctaaattcaa tatagagaac agagtaacaa taagaataaa tagatagggt
     7861 ataaaagttc taggagattt atattatatg ct
//
LOCUS       DBEJJV010000067         6966 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.067, whole genome shotgun sequence.
ACCESSION   DBEJJV010000067 DBEJJV010000000
VERSION     DBEJJV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6966
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.067"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(112..387)
                     /locus_tag="ACL3GT_002011"
     CDS             complement(112..387)
                     /locus_tag="ACL3GT_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HGR0517608.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="ACL3GT_002012"
     CDS             complement(494..1333)
                     /locus_tag="ACL3GT_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HGR0517609.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="ACL3GT_002013"
     CDS             1475..2323
                     /locus_tag="ACL3GT_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HGR0517610.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="ACL3GT_002014"
     CDS             complement(2416..3333)
                     /locus_tag="ACL3GT_002014"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HGR0517611.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3812..3960
                     /locus_tag="ACL3GT_002015"
                     /pseudo
     CDS             3812..3960
                     /locus_tag="ACL3GT_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="ACL3GT_002016"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="ACL3GT_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HGR0517612.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="ACL3GT_002017"
     CDS             complement(4596..4940)
                     /locus_tag="ACL3GT_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HGR0517613.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="ACL3GT_002018"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="ACL3GT_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HGR0517614.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5306..5393)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5452..6156)
                     /locus_tag="ACL3GT_002019"
     CDS             complement(5452..6156)
                     /locus_tag="ACL3GT_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HGR0517615.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKASF"
     gene            6561..6860
                     /locus_tag="ACL3GT_002020"
     CDS             6561..6860
                     /locus_tag="ACL3GT_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HGR0517616.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2194 a         1412 c         1160 g         2200 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaagat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccgcctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggcgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattgt acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatctgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggcaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccaaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt
     3781 ccaacaactc ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaattg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg gtatcaaaat aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgaa cctttttatt ttgcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaatagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcactcctca gctcgccatc ttcggctctc
     4921 tcaaagactg cctgtatcat gtgttctcct taaaattaag cgttgattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa ccactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa cgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacga
     5341 accacttaaa cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata
     5401 gtcaactctt caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatga
     5461 agctttttct tttacttttt tctgccaaga ggcaaaaagc atgctgaggt aaaaaacgct
     5521 catcataata ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga
     5581 aaagacaacg ccaaggacaa aactactaag caggctaaca aatatgaatc cttcacgcaa
     5641 aaaaggagtg tgcttggttc ggaaataatc tccaaaagcc agcatggtcc gtttgatatt
     5701 ccctgtcata aaagcgttat tataggcaat acccgacact tctccaaaag cagttgtcac
     5761 cagtcccata cagaaggcca agggcggcac tagatagata ttatccacag tttgcggcac
     5821 aaaagcaata atgattgata agattgccaa gggaatcaag gacagaatag gttttttcac
     5881 aattctcaat ttttccttat aaatcgttaa taaaaagact cccatcataa acgctagcaa
     5941 ggtgagaacc ttgtccctaa catccgaaac attattttta attaattcta ctgaaagaaa
     6001 gacaacattt ccagtttgtc cagctacaag ggtattcccg cgaacaataa aagtgtaagc
     6061 atccacatat ccagcacaaa acgtcaaaaa aagtgctaac cttttagact gacgtgatat
     6121 ttttcttata ggtaataacc tcattttacc tcccattgta ttttctctta gaaatattgt
     6181 accattttct ttctaaaaaa tcgtaggcta ccatttagat tttactatta gcataaaaat
     6241 aataataata gacaactatt tatccaaaaa tagatagatg taacatgttt gcaaacaaag
     6301 catacgaacc tttagtaaaa tcatttccat gaaactagaa tagagccctc ttagcaaaaa
     6361 tcattatttt aatttatttc taatcactcc ttgacataaa taactctcac caataaaaga
     6421 ctatgtctta aaaaaatggt ataataaaat caatacttgg gcttgatggc tatgctacta
     6481 ataacaatta ggagagaaaa tcaggcactt gttaacaaca aggattatcc ccttgagatg
     6541 aaaggaactt tagaaatctt atgatgaaca tgcaaaacat gatgcgtcaa gcacaaaaac
     6601 ttcaaaaaca aatggaacaa agccaagctg aacttgctgc tatgcaattt gttggcaaat
     6661 ctgctcaaga tcttgtccaa gcgaccttaa ctggcgataa gaaagttgtc agcattgatt
     6721 tcaatccagc tgtcgttgac ccagaggacc ttgagactct ttctgatatg accgttcaag
     6781 ccatcaactc tgctcttgaa caaatcgatg aaactaccaa gaaaaaactg ggtgctttcg
     6841 ctgggaaatt acctttctaa aaacaaggag ctagaacaat gcttgtcgat aacaaaggct
     6901 aagaaaggtg caaaaatgac tctataatat ttgtagtggg taaatcccct atagatatta
     6961 tggagc
//
LOCUS       DBEJJV010000068         6719 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.068, whole genome shotgun sequence.
ACCESSION   DBEJJV010000068 DBEJJV010000000
VERSION     DBEJJV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6719
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.068"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..141
                     /locus_tag="ACL3GT_002021"
                     /pseudo
     CDS             1..141
                     /locus_tag="ACL3GT_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            308..508
                     /locus_tag="ACL3GT_002022"
     CDS             308..508
                     /locus_tag="ACL3GT_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517617.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            550..955
                     /locus_tag="ACL3GT_002023"
                     /pseudo
     CDS             550..955
                     /locus_tag="ACL3GT_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane domain-containing protein"
     gene            1186..1893
                     /gene="ccdA2"
                     /locus_tag="ACL3GT_002024"
     CDS             1186..1893
                     /gene="ccdA2"
                     /locus_tag="ACL3GT_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HGR0517618.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1904..2461
                     /gene="sdbB"
                     /locus_tag="ACL3GT_002025"
     CDS             1904..2461
                     /gene="sdbB"
                     /locus_tag="ACL3GT_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HGR0517619.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKIVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2835..4226
                     /locus_tag="ACL3GT_002026"
     CDS             2835..4226
                     /locus_tag="ACL3GT_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HGR0517620.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4369..5286
                     /gene="adcAII"
                     /locus_tag="ACL3GT_002027"
     CDS             4369..5286
                     /gene="adcAII"
                     /locus_tag="ACL3GT_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HGR0517621.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5294..>6719
                     /gene="phtD"
                     /locus_tag="ACL3GT_002028"
     CDS             5294..>6719
                     /gene="phtD"
                     /locus_tag="ACL3GT_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HGR0517622.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPVQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVRDSRPEQPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEKNGVSRYIPAKNLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT         2067 a         1241 c         1413 g         1998 t
ORIGIN      
        1 atttctttgg ttgcaggtct aacaaatggt gaattaatcg ctccaatgac ttacgaagag
       61 atgatgacga gcgacttttt tgaagtatgg tttcagaagt ttctcttacc aacattaacc
      121 acaccatcgg ttattatagt aaaatgaaat aagaacagga caaatcgatc aggacagtaa
      181 aatcgaattc taacaatgtt ttagaagtcc atatgtacta ttctagtttc aatataccat
      241 aactgttcct agtcaacctg caagccctgt cccagctcca agctcagctc cgactcaaga
      301 tcctagagtg gtagcaagcg cttcggctag ctcaacgagc acacaagctc aagagcaagt
      361 tgacaagtct gaacttcgtg ccttgagtca agagttagac caacgcttga aagctttggc
      421 aacagtatct gatccgaaaa tcgatgcaac caaggctgtc ctcctagatg ctcaaaaagc
      481 tccggaagat agtgccttga cagagtaagg tctgcatact gcagtagagt ctgtgaaggc
      541 tgggctgcct tggactctct caaagatgtg aaagcaaatg ctagcgacag caagcctaca
      601 caggacaaga aggatgcaaa acaaggaacg gaagatagta aggattcaga taagatgact
      661 gaaacaaact cagttccagc aggagtgatt gtggtcagtc tacttgccct cctaggcgtg
      721 attgccttct ggctaattcg ccgtaagaaa gagtcagaaa tccagcaatt aagcacggaa
      781 ttgaccaagg ttctaggaca gctagatgca gaaaaaagcg gataaaaaag tccttgccaa
      841 agcccaaaac cttctccaag aaacccttga tttcgtgaaa gaagaaaatg gctcagcaga
      901 gacagaaact aaactagtag aggagcttaa agcaatcctt gacaaactca agtaaaacat
      961 gatttatgaa atgtcagacc taaaagacat tttcgttcac aaaagcagcg acgagtaatc
     1021 cttgtcgttg ctttttggct attttggggg ataagatccg ccttgactag caaaagaaaa
     1081 gattggtcca atagtgcccg atacgatttt gcgtagcaga aagcttacaa ataaaattga
     1141 atatagtaaa ataggattag aattattaag aaagttggtt ctttattgga aacgatagta
     1201 tttttaatct ctgtttttct agcaggtgtt ttatcctttt tttctccttg tatttttcct
     1261 cttctgccag tctatgctgg gattttattg gatgatcaag aaagtgcaaa aagcttttct
     1321 ttgtttggga gaaaggttct ctggtcaggc ttgattcgaa cactttgctt tatcgctggt
     1381 atctctctca ttttctttat tctaggcttt ggtgctggtt actttggtca tattctctat
     1441 gcaaattggt ttcgatatgg catgggagct attattatca ttttgggtct tcaccagatg
     1501 gaaatttttc atttgaagaa attagaagtt caaaaaagtt ttacctttaa aaaatcagac
     1561 tctaatcgtt attggtcagc ttttttactt ggtattacct ttagctttgg ttggacacct
     1621 tgtattggtc cagttttaag ttctgtttta gcacttgcgg cttctggagg caatggcgct
     1681 tggcaaggag cgatttatac tctcatttac actctgggca tggcccttcc tttcttggta
     1741 ttggcactag cttcaggtct agtcatgcca tattttagta aaatcaagcg tcatatgatg
     1801 ctactaaaga aaattggtgg tttcctcatt gttttaatgg gaattttgtt actattagga
     1861 caagtaaatg ttctagctgg aatttttgaa taaaggagga caaatgaaaa aagtaatgtt
     1921 tgctggctta agtctcttgt cattagttgt attgatggcc tgtggtgagg aagaaactaa
     1981 aaagactcaa gcagcacaac agccaaaaca acaaacgact gtacaacaaa ttgctgttgg
     2041 aaaagatgct ccaaacttca cattgcaatc catggatggc aaagaagtta agttatctga
     2101 ttttaagggt aaaaaggttt acttgaagtt ttgggcttca tggtgtggtc catgcaagaa
     2161 aagtatgcca gagttgatgg aactagcggc gaaaccagat cgtgatttcg aaattcttac
     2221 tgtcattgca ccaggaattc aaggtgaaaa aattgttgag caattcccac aatggttcca
     2281 ggaacaagga tataaggata tcccagttct ttatgatacc aaagcaacca ccttccaagc
     2341 ttatcaaatt cgaagcattc ctacagaata tttaattgat agccaaggaa agattggaaa
     2401 gattcaattt ggtgctatca gtaatgcgga tgcagaagca gcatttaaag aaatgaacta
     2461 gaatcgataa aatctgatta caagatgtag tcagattttg gtaacttcta aaactaactt
     2521 ccagtttccc acaacctagc ttttagtatg agaaaaacgc gtgacatcag tggaaatccg
     2581 tcttagacta acttccactg gttttctttt tcttgatata taagggttca aaagcgaaaa
     2641 gactcagaaa aagtgcacga caaatagccc taaaacagag tcgtcttaga gtaacttcca
     2701 gttttgggag agagatggaa gttactttga gaagttacgg tagtcagatt tttttagaaa
     2761 aacattttat aaatattcac atatctccta tatttatggt aaaatagaat catcagttta
     2821 ttttggagtc aaagatgaat atatttagaa caaagaatgt tagtttagat aaaacagaga
     2881 tgcataggca tttgaagtta tgggatttga ttttgctggg tatcggagcc atggtaggga
     2941 caggcgtctt tacaatcaca ggtactgcag ctgcaacact tgctggccca gccctagtga
     3001 tttcaatcgt tatttctgcc ttgtgtgtgg gattatcagc cctctttttt gcagaatttg
     3061 cctcgcgagt acccgctaca ggaggtgcct atagttacct ctatgctatc ttaggagaat
     3121 tccctgcctg gttggctggt tggttaacca tgatggagtt catgacagcc atatcaggcg
     3181 tagcttcggg ttgggcagct tattttaaag gcttgctctc tcaatacggg atagcctttc
     3241 ctcaggcttt aaatggtacc tttaatcctc aagcagggac atttgttgat ttattgccta
     3301 ttcttgtctt ggtcttggtg acttcgcttg ttttactaaa tgccaaggca gccttacgct
     3361 ttaattcgat tctagttatt ttgaaatttt ccgctttagc tctctttgtt ttagtaggaa
     3421 tttggaatat taagtttgat aattggagca attttgctcc ttacggtttt ggacaaatct
     3481 atggagctag cactggtatt atggctggtg cgtccttgat gttcttcggt tttttgggat
     3541 ttgaatccat ctctatggct gtagatgaag tcaagactcc tcaaaaaaat attcctagag
     3601 ggattgtctt atcgctttct atcgtaacca ttctctatgc cttggtgacc cttgttttga
     3661 ctggtgtggt tcactatagt catttaaatg tcgatgatgc cgttgccttt gcccttcgta
     3721 gtgttgggat tagttgggca gccaactatg tgtcattagt ggctatcttg accttgatta
     3781 cagtttgtat ttcgatgacc tatgccctat cgcgtatgat ttacagttta gcacgtgacg
     3841 gcttagtgcc tgctgccttt aaggaactga cgaagactag caagatacca aagaatgcta
     3901 ctatcttgac aggtctagct tcagcagtag cagcaggaat gttcccacta gccagtattg
     3961 cagccttttt aaatatttgt accttagcct acttgatcat gttggcttat ggtctgattc
     4021 gcttacggaa agaaaaagga atgcccaaag ctggggaatt taaaacacca ttggtacctc
     4081 tgttaccaat tttatcgatc atcatttgtt tatccttcat gttacagtat aatatgaata
     4141 cctggattgc tttcctagtt gcgttgttag taggaagtat tatttacttc acttatggct
     4201 ataagcattc taccatagaa gaataaagtg aaagtctatt gagttgttga cactcagcag
     4261 atttttatat gtgaaagaaa tttcaaattt tttctaaaaa tatcttgaca gattaaattt
     4321 tcaggagtag aatatttact agttaattaa atggttaagg agttgttcat gaagaaacaa
     4381 aatttatttt tagtcctgtt aagtgtcttt cttttgtgct tgggggcttg tggtcaaaag
     4441 gaaagtcaga caggaaaggg gatgaaaatt gtgaccagtt tttatcctat ctacgctatg
     4501 gttaaggaag tatctggtga cttgaatgat gttcggatga ttcagtcaag tagtggtatt
     4561 cactcctttg aaccttcggc aaatgatatc gcagccatct atgatgcaga tgtctttgtt
     4621 taccattctc atacactcga atcttgggca ggaagtctgg atccaaatct aaaaaaatcc
     4681 aaagtgaagg tcttagaggc ttctgaggga atgaccttgg aacgtgtccc tggactagag
     4741 gatgtggaag caggggatgg agttgatgaa aaaacgctct atgaccctca cacatggcta
     4801 gatcctgaaa aagctggaga agaagcccaa attatcgctg ataaactttc agaggtggat
     4861 agtgagcata aagagactta tcaaaaaaat gcgcaagcct ttatcaaaaa agctcaggaa
     4921 ttgactaaga aattccaacc aaaatttgaa aaagcgactc agaaaacatt tgtaacacaa
     4981 catacagcct tttcttatct agcgaagaga tttgggctta atcaacttgg tattgcaggt
     5041 atctctcctg aacaagaacc aagtccacga caactaacag aaattcagga atttgttaag
     5101 acctataagg ttaaaacgat ttttacagaa agtaacgctt cttcaaaagt agctgaaact
     5161 cttgtcaaat caacaggtgt gggtcttaaa actctgaatc ctttagagtc agacccacaa
     5221 aatgacaaga cctatttaga aaatcttgaa gaaaatatga gtattctagc agaagaatta
     5281 aagtgaggaa agaatgaaaa tcaataaaaa atatctagca ggttcagtgg cagtccttgc
     5341 cctaagtgtt tgttcctatg aacttggtcg tcaccaagct ggtcaggtta agaaagagtc
     5401 taatcgagtt tcttatatag atggtgatca ggctggtcaa aaggcagaaa atttgacacc
     5461 agatgaagtc agtaagagag aggggatcaa cgccgaacaa attgttatca agattacgga
     5521 tcaaggttat gtgacctctc atggagacca ttatcattac tataatggca aggttcctta
     5581 tgatgccatc atcagtgaag aacttctcat gaaagatccg aattatcagt tgaaggattc
     5641 agacattgtc aatgaaatca agggtggcta tgtgattaag gtagacggaa aatactatgt
     5701 ttaccttaaa gatgcggccc atgcggacaa tattcggaca aaagaagaga ttaaacgtca
     5761 gaagcaggaa cgcagtcata atcataactc aagagcagat aatgctgttg ctgcagccag
     5821 agcccaggga cgctacacca cagatgatgg ttatatcttt aatgcttctg atatcattga
     5881 ggacacgggt gatgcttata tcgttcctca cggcgaccat taccattaca ttcctaagaa
     5941 tgagttatca gctagcgagt tagctgctgc agaagcctat tggaatggga agcagggatc
     6001 tcgtccttct tcaagttcta gttataatgc aaatccagtt caaccaagat tgtcagagaa
     6061 ccacaatctg actgtcactc caacttatca tcaaaatcaa ggggaaaaca tttcaagcct
     6121 tttacgtgaa ttgtatgcta aacccttatc agaacgccat gtggaatctg atggccttat
     6181 tttcgaccca gcgcaaatca caagtcgaac cgccagaggt gtagctgtcc ctcatggtaa
     6241 ccattaccac tttatccctt atgaacaaat gtctgaattg gaaaaacgaa ttgctcgtat
     6301 tattcccctt cgttatcgtt caaaccattg ggtacgagat tcaagaccag aacaaccaag
     6361 tccacaatcg actccagaac ctagtccaag tccgcaacct gcaccaaatc ctcaaccagc
     6421 tccaagcaat ccaattgatg agaaattggt caaagaagct gttcgaaaag taggcgatgg
     6481 ttatgtcttt gagaagaatg gagtttctcg ttatatccca gccaagaatc tttcagcaga
     6541 aacagcagca ggcattgata gcaaactggc caagcaggaa agtttatctc ataagctagg
     6601 agctaagaaa actgacctcc catctagtga tagagaattt tacaataagg cttatgactt
     6661 actagcaaga attcaccaag atttacttga taataaaggt cgacaagttg attttgagg
//
LOCUS       DBEJJV010000069         6524 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.069, whole genome shotgun sequence.
ACCESSION   DBEJJV010000069 DBEJJV010000000
VERSION     DBEJJV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6524
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.069"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            125..325
                     /locus_tag="ACL3GT_002029"
     CDS             125..325
                     /locus_tag="ACL3GT_002029"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HGR0517623.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            360..1076
                     /gene="atpB"
                     /locus_tag="ACL3GT_002030"
     CDS             360..1076
                     /gene="atpB"
                     /locus_tag="ACL3GT_002030"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HGR0517624.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            1090..1584
                     /gene="atpF"
                     /locus_tag="ACL3GT_002031"
     CDS             1090..1584
                     /gene="atpF"
                     /locus_tag="ACL3GT_002031"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HGR0517625.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            1584..2120
                     /locus_tag="ACL3GT_002032"
     CDS             1584..2120
                     /locus_tag="ACL3GT_002032"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HGR0517626.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            2135..3640
                     /gene="atpA"
                     /locus_tag="ACL3GT_002033"
     CDS             2135..3640
                     /gene="atpA"
                     /locus_tag="ACL3GT_002033"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HGR0517627.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            3656..4534
                     /locus_tag="ACL3GT_002034"
     CDS             3656..4534
                     /locus_tag="ACL3GT_002034"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HGR0517628.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            4620..6026
                     /gene="atpD"
                     /locus_tag="ACL3GT_002035"
     CDS             4620..6026
                     /gene="atpD"
                     /locus_tag="ACL3GT_002035"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HGR0517629.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            6037..6456
                     /locus_tag="ACL3GT_002036"
     CDS             6037..6456
                     /locus_tag="ACL3GT_002036"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HGR0517630.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
BASE COUNT         1939 a         1219 c         1442 g         1924 t
ORIGIN      
        1 acttgaaatt tagcaaaatg gaaataattt ttattaaacg cttccaatag cggttaaaag
       61 ttgacaaatt taaattttag gactacacta agtaagtaaa ttttatttta aaggagaatt
      121 tgttatgaat ttaacatttt taggcttatg tattgcctgt atgggcgtat ctgtcggtga
      181 aggtttattg atgaatggac tgtttaaatc agtagcacgc caaccagata tgctttctga
      241 gtttcgtagt ttgatgtttt taggtgttgc ctttattgaa ggaactttct ttgtaactct
      301 tgtcttctca tttattatca aataaataca tggaacgaga agaaaaggga ggattttaga
      361 tggaagaaag tattaatcca atcatctcta ttggtcctgt tatcttcaat ctgactatgt
      421 tagccatgac tttgttgatt gtgggagtta tttttgtctt tatttattgg gcaagccgca
      481 atatgacctt gaaacccaaa ggaaagcaaa atgtacttga gtatgtctat gactttgtta
      541 ttggatttac agaacctaac attggttcgc gctacatgaa agattactca ctctttttcc
      601 tttgtttatt ccttttcatg gtgattgcca ataaccttgg cttaatgaca aagcttcaaa
      661 cgatcgatgg gactaactgg tggagttcgc caaccgctaa tttacagtat gacttaacct
      721 tatcttttct tgtcattttg ttgacacata tagaaagcgt tcgtcgtcgt ggatttaaaa
      781 aaagtataaa atcttttatg agtcctgttt ttgtcatacc gatgaatatc ttggaagaat
      841 ttacaaactt cttatctttg gctttgcgga tttttgggaa tatctttgca ggagaggtca
      901 tgacgagttt gttacttctt ctttcccacc aagctattta ttggtatcca gtagcctttg
      961 gagctaattt ggcttggact gcattttctg tctttatttc ctgcatccaa gcttatgttt
     1021 ttactctttt gacatctgtg tatttaggga ataagattaa tattgaagag gaatagaaag
     1081 gagtaactga tgcacgtaac agtaggtgaa ttaattggta attttatttt aatcactggc
     1141 tcttttattc ttttgctagt cttgattaaa aaatttgcat ggtctaatat tacaggcatt
     1201 ttcgaagaaa gagctgaaaa aattgcttca gatattgaca gagctgaaga agcccgtcaa
     1261 aaagcagaag tattggctca aaaacgcgaa gatgaattgg ctggtagccg taaagaagct
     1321 aagacaatca ttgaaaatgc aaaggaaaca gctgagcaaa gtaaggctaa tatcttagca
     1381 gatgctaaac tagaagcagg acacttaaaa gaaaaagcca atcaagaaat tgctcaaaat
     1441 aaagtagaag ctttacagag tgttaagggt gaggtcgcag atttgaccat cagcttagct
     1501 ggtaaaatca tctcacaaaa ccttgacagt catgcccata aagcactcat tgatcagtat
     1561 atcgatcagc taggagaagc ttaatggaca agaaaacagt aaaggtaatt gaaaaataca
     1621 gcatgccttt tgtccaattg gtacttgaaa aaggagaaga agaccgtatc ttttcagact
     1681 tgactcaaat caagcaagtt gttgaaaaaa caggtctgcc ttctttttta aaacaagtgg
     1741 cagtagacga gtcggataag gaaaaaacaa ttgctttttt ccaagattct gtgtcgcctt
     1801 tattacaaaa ctttatccag gttctggcct acaatcacag agcaaatctt ttttatgatg
     1861 tgcttgtaga ttgcttgaac cgacttgaaa aagaaacaaa tcgatttgaa gtgacgatta
     1921 cgtctgctca tcctctaact gatgaacaga agactcgttt gctccctttg attgagaaaa
     1981 aaatgtctct gaaagtaagg agtgtaaaag aacaaatcga tgaaagtctc attggtggtt
     2041 ttgtcatttt tgccaatcac aagacaattg atgtgagtat taaacaacaa cttaaagttg
     2101 ttaaagaaaa tttgaaatag aaagtggtgt tcttttggca attaacgcac aagaaatcag
     2161 cgctttaatt aagcaacaaa ttgaaaattt caaacccaat tttgatgtga ctgaaacagg
     2221 tgttgtaacc tatatcgggg acggtatcgc gcgtgctcat ggccttgaaa atgtcatgag
     2281 tggagagttg ttgaattttg aaaacggctc ttatggtatg gctcaaaact tggagtcaac
     2341 agacgttggt attatcatcc taggtgactt tacagatatc cgtgaaggcg atacaatccg
     2401 ccgtacaggg aaaatcatgg aagtccctgt aggtgaaagt ctgattggtc gtgttgtgga
     2461 tccgcttggt cgtccagttg acggtcttgg agaaatccac actgataaaa ctcgtccagt
     2521 agaagcacca gctcctggtg ttatgcaacg taagtctgtt tcagaaccat tgcaaactgg
     2581 tttgaaagct attgacgccc ttgtaccgat tggtcgtggt caacgtgagt tgattatcgg
     2641 tgaccgtcag acagggaaaa caaccattgc gattgataca atcttgaacc aaaaagatca
     2701 agatatgatc tgtatctacg tcgcgattgg acaaaaagaa tcaacagttc gtacgcaagt
     2761 agaaacactt cgtcagtacg gtgccttgga ctacacaatc gttgtgacag cctctgcttc
     2821 acaaccatct ccattgctct tcctagctcc ttatactggg gttgctatgg cggaagaatt
     2881 tatgtatcaa ggtaagcatg ttttgattgt atacgatgat ctatcaaaac aagcggtagc
     2941 ttatcgtgaa ctatcgctct tgcttcgtcg tcctccaggt cgtgaagcct tcccagggga
     3001 tgttttctat ctccacagcc gtttgcttga gcgctcagct aaagtttctg atgaacttgg
     3061 tggtggatca attacagccc taccatttat cgagacacaa gcaggagata tctcagccta
     3121 tatcgcaacc aacgtgattt ctatcactga tggacaaatc ttccttggcg atggcctctt
     3181 caatgcaggt attcgtccag ccatcgatgc gggttcatct gtatctcgtg taggtggttc
     3241 tgcacaaatc aaagccatga agaaggttgc tggtacactt cgtatcgacc ttgcttcata
     3301 ccgtgagttg gaagccttta ctaagtttgg ttctgacttg gacgcagcaa cacaggctaa
     3361 gttgaaccgt ggacgtcgta ccgttgaggt cttgaaacaa cctgttcaca aaccattacc
     3421 tgttgagaaa caagtaacca ttctttatgc tttgacacat ggtttcttgg atactgttcc
     3481 agtagatgat attgttcgtt tcgaggaaga gttccatgcc ttctttgatg ctcaacatcc
     3541 agagattttg gaaaccattc gtgatacaaa agacttgcca gaagaagcag tcttggatgc
     3601 tgcgattaca gagtttctca atcaatctag cttccaataa gaatagaggt gtcagatggc
     3661 agtgtctcta aatgatatta aaacaaaaat cgcctcaaca aaaaatacga gtcaaatcac
     3721 taatgccatg caaatggtat cggctgctaa gttaggtcgc tctgaagaag ctgctcgcaa
     3781 cttccaagtt tacgctcaga aagtgcgtaa acttttgaca gatatccttc atggtaatgg
     3841 agctggtgct tcaactaatc cgatgttgat tagccgttct gtgaagaaga caggctatat
     3901 cgttatcact tcagaccgcg gtttggttgg aggttataat tcctctattt tgaaagctgt
     3961 tatggagttg aaagaagaat accacccaga cggtaaaggt tttgaaatga tctgtatcgg
     4021 tgggatggga gctgatttct ttaaggctcg cggtattcaa ccactttatg aattacgtgg
     4081 cttggcagac caacctagct ttgatcaagt tcgtaagatt atttcaaaaa ctgttgaaat
     4141 gtaccaaaat gaactctttg atgagcttta tgtttgctac aaccaccatg tcaatacgct
     4201 aaccagtcaa atgcgtgtgg aacaaatgct tccgattgtt gacttggatc caaatgaagc
     4261 ggatgaagag tacagcttga cttttgaatt ggaaaccagc cgagaagaaa ttctggagca
     4321 gttgttgcct cagtttgcag aaagtatgat ttacggtgcc attatcgatg ccaagacagc
     4381 tgagaatgct gcgggtatga cagccatgca aacagcgaca gataatgcta agaaagtcat
     4441 caatgatttg acaattcagt ataaccgtgc cagacaggcg gcgattacac aagaaattac
     4501 agaaatcgta gcaggtgcta gtgccttaga ataggctcta gtccagctcg tatgaaaatg
     4561 aacttaggac ctagttgagc taggaaccga cagtatctta tatagaatag gagaaggaga
     4621 tgagttcagg taaaattgct caggttatcg gtcccgttgt agacgttttg tttgcagcag
     4681 gggaaaaact tcctgagatt aacaatgcac ttgtcgtcta caaaaatgac gaaagaaaaa
     4741 caaaaatcgt ccttgaagta gccttggagt taggagatgg tatggttcgt actatcgcca
     4801 tggaatcaac agatgggttg actcgtggaa tggaagtatt ggacacaggt cgtccaatct
     4861 ctgtaccagt aggtaaagaa actttgggac gtgtcttcaa cgttttggga gataccattg
     4921 atttggaagc tccttttaca gaagacgcag agcgtcagcc aattcataaa aaagctccaa
     4981 cttttgatga gttgtctacc tcttctgaaa tccttgaaac agggatcaag gttattgacc
     5041 ttcttgcccc ttaccttaaa ggtggtaaag ttggactttt cggtggtgcc ggagttggta
     5101 aaaccgtctt aatccaagaa ttgattcaca acattgccca agagcacggt ggtatttcag
     5161 tatttactgg tgttggggaa cgtactcgtg aggggaatga cctttactgg gaaatgaaag
     5221 aatcaggcgt tatcgagaaa acagccatgg tctttggtca gatgaatgag ccaccaggag
     5281 cacgtatgcg tgttgccctt actggtttga caatcgctga atacttccgt gatgtggaag
     5341 gccaagacgt gcttctcttt atcgataata tcttccgttt cactcaggct ggttcagaag
     5401 tatctgccct tttgggtcgt atgccatcag ccgttggtta ccaaccaaca cttgctacgg
     5461 aaatgggtca attgcaagaa cgtatcacat caaccaagaa gggttctgta acctctatcc
     5521 aggctatcta tgtgccagcg gatgactata ctgacccagc gccagcaaca gccttcgctc
     5581 acttggattc aacaacaaac ttggaacgta aattggtaca attgggtatc tacccagccg
     5641 ttgacccact tgcttcaagc tcacgtgcct tggcacctga aatcgttgga gaagagcact
     5701 atgcagttgc tgctgaagta aaacgtgtcc ttcaacgtta ccatgaattg caagatatca
     5761 ttgctatcct tggtatggat gagctttctg atgaagaaaa gaccttggtt gctcgcgccc
     5821 gtcgtatcca gttcttcttg tcacaaaact tcaacgttgc ggaacaattt actggtcagc
     5881 caggttctta tgttccagtt gctgaaactg tacgtggctt taaggaaatc cttgatggta
     5941 aatacgacca cttgccagaa gatgccttcc gtggtgtagg ttctatcgaa gatgtgattg
     6001 caaaagctga aaaaatggga ttttaagagg tgacctatgg ctcagttaac tgtccagatc
     6061 gtgacaccag atggtctcgt ctatgatcac catgccagct atgtatcggt tcgaactctg
     6121 gatggtgaga tggggatctt gccacgacat gaaaatatga ttgcggtttt agcagttgat
     6181 gaagtaaagg taaaacgtat cgatgataaa gatcacgtga actggattgc agtaaacggt
     6241 ggcgttattg aaattgccaa tgatatgatc acaatcgtcg ctgactctgc agaacgtgct
     6301 cgtgatatcg atattagccg tgcagaacgt gccaaacttc gtgcagaacg tgcaattgaa
     6361 gaagcacaag acaaacattt gattgaccaa gaacgtcgtg ctaagattgc tttgcaacgt
     6421 gccattaacc gtattaatgt cggaaataga ctataagaaa aaatgaactt gaaaatacca
     6481 agttcatttt ttaggctctt tgtcaactgt agtgggttga aaaa
//
LOCUS       DBEJJV010000070         6484 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.070, whole genome shotgun sequence.
ACCESSION   DBEJJV010000070 DBEJJV010000000
VERSION     DBEJJV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 6484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6484
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.070"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            100..1075
                     /locus_tag="ACL3GT_002037"
                     /pseudo
     CDS             100..1075
                     /locus_tag="ACL3GT_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            1252..2259
                     /gene="gap"
                     /locus_tag="ACL3GT_002038"
     CDS             1252..2259
                     /gene="gap"
                     /locus_tag="ACL3GT_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HGR0517631.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2327..3202)
                     /locus_tag="ACL3GT_002039"
     CDS             complement(2327..3202)
                     /locus_tag="ACL3GT_002039"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HGR0517632.1"
                     /translation="MQFTFTLPASLPQMTVKQLLEEQLLIPRKIRHFLRIKKHILINQ
                     EEVRWNEIVNPGDVCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTH
                     GNQPNEIALLNHVSTYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISR
                     EYWALVDGNINRKELVFRDKIGRDRHDRRKRIVDAKNGKYAETHVSRLKQFSNKTSLA
                     HCKLKTGRTHQIRVHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTF
                     TTLSNTFEKELKKNG"
     gene            3289..5484
                     /gene="pbp2a"
                     /locus_tag="ACL3GT_002040"
     CDS             3289..5484
                     /gene="pbp2a"
                     /locus_tag="ACL3GT_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP2A"
                     /protein_id="HGR0517633.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLKNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYNSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5537..5689
                     /gene="rpmG"
                     /locus_tag="ACL3GT_002041"
     CDS             5537..5689
                     /gene="rpmG"
                     /locus_tag="ACL3GT_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HGR0517634.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5699..5875
                     /gene="secE"
                     /locus_tag="ACL3GT_002042"
     CDS             5699..5875
                     /gene="secE"
                     /locus_tag="ACL3GT_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HGR0517635.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            5930..6466
                     /gene="nusG"
                     /locus_tag="ACL3GT_002043"
     CDS             5930..6466
                     /gene="nusG"
                     /locus_tag="ACL3GT_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HGR0517636.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2014 a         1127 c         1412 g         1931 t
ORIGIN      
        1 ttttatgagg ctcttttgtc ctgctcttgt ttcaattgac tatagttcac ggatacagtt
       61 gggaaagaag ctattaaata tttggagagt ccttttggga tgaacatgtc aaatattact
      121 atagatgggc aagaaaagat gggcaagaaa tggatctgag tcaaacgatg cttcttatgc
      181 tcaagtagtg agtctttatg atgatacaag tatctctgtt agtaataatg agacggacaa
      241 agtgttgact ggatccctct atactgaaac aaatgaacag ggattaacga ttccaagcag
      301 tttactaaaa aattggaatg aacagacagg aaaaaatttg acaactaatg atcttattgg
      361 caaatcagtc tcagccagca ttgtagaaag tgctgccgaa actagtaaga ttgctcaatt
      421 tcaaacgaag attgtacgtg taatcaatga tgaagatgac atggaggaca gcaacagttt
      481 catgctgtct catcaaatgg aaacgatttt gaaagaggct ggatttacga aagctgtatc
      541 ttattttatc ttggaactca aagatccatc acagacaaaa gtagtaacag aagaattaca
      601 gaaaaataag aagtatactg tgctttctca acagagagtt cttgatattg tgattacctt
      661 tattcgtgtt attcagggat tattgattgt gctttcatca caagctattg tggtagcagc
      721 ggttatgatt ggtatcatta tttacatcaa tatcatgcaa cgttccaagg aaataggtgt
      781 catgaaagca gttggttatc agaatcgtgg tgtcaaagga atttttattt acgaggctat
      841 ctggattgta ggcatcgcct tgctgctggc atttttggtt gcacaagggg tgggaagttt
      901 ggcgaatgcg attgtaagtc acttttaccc atccatcact aaggtttttg aattaaatct
      961 tttatctgtt ttaggaactc tagttttcgc tctattactt ggttatgtct cagcctactt
     1021 cccggcgcgt aagattagta aaatggatcc tgtagaatcg ttacgctatg aataataagg
     1081 gattccttga tttacagtct taaaaagaaa ctcacataga aaaacaatgg ccatacttgc
     1141 aattcaactc aaatagttgt ataataggtt tgttgaaagg tgatttgtag tgattcaagt
     1201 tactcttttc acaataaaaa tttcatgatt ttcataagga ggaaatcact aatggtagtt
     1261 aaagttggta ttaacggttt cggacgtatc ggtcgtcttg ctttccgtcg tatccaaaac
     1321 gtagaaggtg ttgaagttac acgcatcaac gaccttacag atccagttat gcttgcacac
     1381 ttgttgaaat acgacacaac tcaaggtcgt ttcgacggta ctgttgaagt taaagaaggt
     1441 ggattcgaag ttaacggtaa attcgttaaa gtttctgctg aacgtgatcc agagcaaatc
     1501 gactgggcta ctgacggtgt agaaatcgtt cttgaagcta ctggtttctt tgctaagaaa
     1561 gaagcagctg aaaaacacct taaaggtgga gctaaaaaag ttgttatcac tgctcctggt
     1621 ggaaacgacg ttaaaacagt tgtattcaac actaaccacg acgttcttga cggtactgaa
     1681 acagttatct caggtgcttc atgtactaca aactgcttgg ctccaatggc taaagctctt
     1741 caagataact ttggtgttgt tgaaggattg atgactacta tccacgctta cactggtgac
     1801 caaatgatcc ttgacggacc acaccgtggt ggtgaccttc gccgtgctcg cgctggtgct
     1861 gcaaacatcg ttcctaactc aactggtgct gcaaaagcta tcggtcttgt aatcccagaa
     1921 ttgaatggta aacttgatgg atctgcacaa cgcgttccaa ctccaactgg atcagttact
     1981 gaattggtag cagttcttga aaagaacgtt actgttgatg aagtgaacgc agctatgaaa
     2041 gcagcttcaa acgaatcata cggttacaca gaagatccaa tcgtatcttc agatatcgta
     2101 ggtatgtctt acggttcatt gtttgacgca actcaaacta aagttcttga cgttgacggt
     2161 aaacaattgg ttaaagttgt atcatggtac gacaacgaaa tgtcatacac tgcacaactt
     2221 gttcgtactc ttgaatactt cgcaaagatt gctaaataat tcttgagttg atagaaagca
     2281 aggctttgtg gtcttgcttt tttatatgga aaaatggatg acacgatcat ccattctttt
     2341 ttaattcttt ttcaaatgta tttgaaaggg tagtgaaagt tagcctctct aaagtaagtg
     2401 ggtgggtaaa ggaaagtcgg aaggcatgaa gcataagccg gcttgtcttt gatttactat
     2461 tatagagagg gtctcccagg ataggaagat tatgatgcaa aaggtgcaca cgaatctgat
     2521 gggttcgccc tgtctttagc ttgcaatgag ccaaggaagt cttgtttgag aattgcttta
     2581 atctgcttac atgcgtttca gcatatttcc cattttttgc atcaactatt ctttttctac
     2641 gatcatggcg atcacgtcca attttgtctc tgaaaacaag ttcttttctg ttgatatttc
     2701 catcaactag agcccaatat tctctagaaa tctctttttt ctccaataag cgattgagaa
     2761 tgggcaggat aaaaggattt ttggcaaaga gaactaagcc actggtttcc atgtccagac
     2821 gatgaacgac atagcaggtt tggccaacat aggtactgac atggttaaga agggcaattt
     2881 cgtttggttg attaccatgc gttttcatcc cctctggttt gtttacaata atcaagtgtt
     2941 gatcttgata aacttcctgc actaagtctg ggttgcccca agggatcgtc ttttggggat
     3001 aatcttcctc gtcaaaagtc aactggcaaa catctccagg atttacgatt tcgttccagc
     3061 ggacttcttc ttgatttatc aaaatatgtt tcttgattct caaaaaatga cggatttttc
     3121 tagggatgag gagttgttcc tcaagtaatt gctttaccgt catttgaggt agagaggcgg
     3181 gtaatgtaaa tgtgaattgc atacagatat tgtaacaaaa aaagccctat ttggatagga
     3241 aatagctaaa ttcttgtctt cctatgatga agatgataaa ataaacgcat gaaattagat
     3301 aaattatttg agaaatttct ttctcttttt aaaaaagaaa caagtgaact agaggactct
     3361 gattctacta tcttacgtcg ctctcgtagt gatcgaaaaa aattagccca agtaggtccg
     3421 attcgaaaat tctggcgtcg ttatcatcta acaaagatta tccttatact aggtttgagt
     3481 gcaggcttgc tagttggaat ctatttgttt gctgtagcca agtcgaccaa tgtcaatgat
     3541 ttgcaaaatg ccttgaaaac tcggactctt atttttgacc gtgaagaaaa agaggctggt
     3601 gccttgtctg gtcaaaaggg aacctatgtt gagctgactg acatcagtaa aaacttgcag
     3661 aatgctgtta ttgcgacaga agaccgttct ttctataaaa atgacgggat taactatggc
     3721 cgtttcttct tggctattgt cactgctgga cgttcaggtg gtggctctac cattacccaa
     3781 cagctggcta aaaacgccta tttatcgcag gatcaaactg ttgagagaaa agcgaaagaa
     3841 tttttccttg ccttagaatt aagcaaaaaa tatagtaagg agcaaattct aaccatgtac
     3901 cttaacaacg cttattttgg aaatggtgtg tggggtgtag aagatgcgag taagaaatac
     3961 tttggagttt ctgcatcaga agtgagtctg gatcaagctg cgactctggc agggatgctc
     4021 aaggggccgg aactgtataa tcccttgaat tccgtagaag attctactaa tcggcgcgat
     4081 actgtcttga agaatatggt tgcagcagga tatattgata aaaaccaaga aaccgaagct
     4141 gctgaagttg atatgacttc gcaattgcac gataagtatg aaggaaaaat ctcagattac
     4201 cgttacccct cttattttga tgcggtggtt aatgaagctg tttccaagta taatctaaca
     4261 gaggaagaga ttgtcaataa tggctaccgc atttacacag agctggacca aaactaccaa
     4321 gcaaatatgc agattgttta tgaaaacaca tcgctatttc cgagggcaga ggatggaacg
     4381 tttgctcaat caggaagtgt agctctcgaa ccgaaaacag ggggagttcg tggagttgtc
     4441 ggtcaagttg ctgacaatga taaaactgga ttccggaatt tcaactatgc aacccaatca
     4501 aagcgtagtc ctggttctac aattaagcct ttagttgttt atacgccagc agttgaagca
     4561 ggctgggctt tgaataagca gttggataac cataccatgc agtataacag ctataaggtt
     4621 gataactatg cagggatcaa aacgagtcga gaagttccta tgtatcaagc cttggcagaa
     4681 tcgcttaatc tacctgctgt tgccactgtt aatgatttgg gtgttgacaa ggcttttgag
     4741 gcaggcgaaa aattcggact caacatggaa aaggtcgacc gtgttcttgg tgtcgccttg
     4801 ggaagcggtg ttgaaaccaa ccctcttcaa atggctcaag catacgctgc ctttgcaaat
     4861 gaaggtttaa tgcctgaagc tcattttatt agtagaattg aaaatgctag tggacaagtt
     4921 attgcgagtc ataaaaattc acaaaaacgg gtgattgata agtctgtagc tgacaagatg
     4981 accagtatga tgttggggac tttcaccaac ggtaccggta ttagttcatc gcctgcagac
     5041 tatattatgg cagggaaaac tggaacaact gaagcagttt tcaatccgga gtacacaagt
     5101 gaccagtggg taattggtta tactccggat gtagtgatta gccactggct tggctttcct
     5161 accactgatg aaaatcacta tctagctggc tctacttcaa acggtgcagc tcatgtcttt
     5221 agaaacattg ccaataccat tttaccttat acgccaggaa gtacctttac ggttgaaaat
     5281 gcttataagc aaaatggaat tgcaccagcc aatacaaaaa gacaagtaca aaccaatgat
     5341 aatagccaga cagatgataa tttgtctgat attcgagggc gtgcgcaaag tctagtagat
     5401 gaggctagcc gggctatctc agatgcgaag attaaggaaa aggctcaaac aatatgggat
     5461 tcgatagtca atctatttcg ttaagatgct tgtcaaagcc tagctttctt gttataatgg
     5521 ataagatgga ggcgttatgg cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc
     5581 gagaaactat tcaatcaaga tcagcggaaa ccccaagcct acacgactag aagtaaataa
     5641 attttgtaag cattgtggca agtacactac acacagagaa acgagatagg agagagcgat
     5701 gcgttttatt ggagatattt ttagacttct taaagacaca acatggccaa ctcgcaagga
     5761 aagctggaga gattttcgtt ctatcatgga atacacagct ttctttgtag taattattta
     5821 catttttgac cagttgattg tttcaggttt gattcgattt attaacattt tttagaagat
     5881 tagtggagtt aattacacta gaaatcttct atttatgaaa ggaaatatca tggatagttt
     5941 tgataaagga tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa
     6001 tctattacaa cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc
     6061 aacacaaaca gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt
     6121 tccaggttat gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa
     6181 cacaccaaat gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt
     6241 attggaacaa gaaattcgtg acattttggt atctatggga caaactgttc aagaatttga
     6301 tttcgatgtt gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac
     6361 tggtaagatt acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa
     6421 tgacacagtt gcagaagtaa acctaaacca aatcgcagaa ttataaccct gagagaggct
     6481 ggag
//
LOCUS       DBEJJV010000071         5304 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.071, whole genome shotgun sequence.
ACCESSION   DBEJJV010000071 DBEJJV010000000
VERSION     DBEJJV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5304
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.071"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(34..264)
                     /locus_tag="ACL3GT_002044"
     CDS             complement(34..264)
                     /locus_tag="ACL3GT_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517637.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(282..923)
                     /locus_tag="ACL3GT_002045"
     CDS             complement(282..923)
                     /locus_tag="ACL3GT_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HGR0517638.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVAFAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(935..1657)
                     /locus_tag="ACL3GT_002046"
     CDS             complement(935..1657)
                     /locus_tag="ACL3GT_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HGR0517639.1"
                     /translation="MKKKRRLLFLMSIVLGMFVGMFKARVESHEIILDVKALMPWISA
                     ICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITG
                     VAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFAT
                     PKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFL
                     LVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1660..1857)
                     /locus_tag="ACL3GT_002047"
     CDS             complement(1660..1857)
                     /locus_tag="ACL3GT_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517640.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNLYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(1857..2063)
                     /locus_tag="ACL3GT_002048"
     CDS             complement(1857..2063)
                     /locus_tag="ACL3GT_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HGR0517641.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2073..2537)
                     /locus_tag="ACL3GT_002049"
     CDS             complement(2073..2537)
                     /locus_tag="ACL3GT_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517642.1"
                     /translation="MIDKVVRNLLLTFFLCKMTKIINFLTTILVKKKKMCYDVSKLRE
                     KKKGAMMWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRLFQEMIGKE
                     PIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            complement(2642..3931)
                     /gene="hisS"
                     /locus_tag="ACL3GT_002050"
     CDS             complement(2642..3931)
                     /gene="hisS"
                     /locus_tag="ACL3GT_002050"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HGR0517643.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETISMAAYFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4009..5256)
                     /locus_tag="ACL3GT_002051"
     CDS             complement(4009..5256)
                     /locus_tag="ACL3GT_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HGR0517644.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDVISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
BASE COUNT         1739 a         1119 c          974 g         1472 t
ORIGIN      
        1 atacaaaaat ccgatgaact tcaccggact cttttatttt gaatttttgc ctgctttacg
       61 cttttcagcg atttcggctg cctttcgagg caagacaatt tccgttatgt aagccgtccc
      121 aaaacgcagt acacctgcaa taggagcaaa gacaactgct agatagttat agaagaaatc
      181 gcctttgaag gcataagcta gcgctccaat gatgaaaaat agaacgactg cctgaatcac
      241 tgctaataaa attactcgtt tcatgtgacc tcctgactct attatagcat gagaatcatc
      301 aaaaagccga ctaaattatt caaagcgtga agagaaatac tgtagaccag accttttctg
      361 ctaatgtaag ccaaacccaa actaaaacca aggctaaaat agacaaaaaa ttgttgcaca
      421 tcacctggaa aatgaatcaa ggcaaataga agactagata ccagaagaaa aatcagggtt
      481 cgtttactat tgtcctgctt aggaaagaga tagcgtgcta acatccctct aaaaacaatc
      541 tcttccgtca aaggagcaaa aataaccaca gcaaagaatg agaaaagtgg ttgagacaag
      601 gtcaagtctg tcgctatttg ctgatttact gaaggatcat ctggcaagaa gaattgaacg
      661 accagagata agaaccaaac caagacagga agccaaataa atcgattaaa gccgctcttc
      721 tcaatatgaa caggagcctt ctgataccat ttgtaaatgc cgtacacata tactccagca
      781 aaggccacat agagtagagt aacagcatag ggtgaagcgc ctaaagcaag cgacgcagtc
      841 gcgagcccct gaataaagcc atagataaat aaaaaggata gaagggctag aagaatccag
      901 ccaaggtttt taagtaattt catagataac tcctttattt gaaataacgt tttaccatag
      961 gtaactgcat cacattgata taaacatgga tggctcctac aagcaagaaa gctagtaact
     1021 gaatctctcc tgtcaagaaa gaaatgataa taagaaaaat atataaggct ggtaagacat
     1081 attggtgtaa ttggaataaa attcgaaaac tctgttccaa attagcctga cgctcccctt
     1141 catcataaga atttatatag ttcaagacat cctttggtgt agcgaaaaat tccaaatcaa
     1201 actgacgaac aatcgcaatg gttttaaaaa gagatttttg agcgactaag aataccacaa
     1261 agagtaagaa agaaaggaaa aatgtttgag ggtttgtatg caatataatc acctcactta
     1321 atgaaataaa aatagccaat ggaatcgcta cacctgtaat attaaaagca atggttccaa
     1381 actcaagatt ccgatacatt tgcacataat aggtttcatt cagatcgtca tccatttcct
     1441 cttgatacaa ggaatgaaat tttctgcttt tctttaagaa attgaaagtc aaaaacatac
     1501 taatgaaacc tatcagtaaa caaatagctg atatccatgg catcaaggct tttacatcta
     1561 aaataatttc gtgggattcg acacgtgcct taaacatccc tacaaacatg cccaagacaa
     1621 tagacatcaa aaataacaat ctacgtttct ttttcatatt cattctcctt tttcacttgc
     1681 tagatttttg gatttctttt caatccattc aattactggg atgagagcaa agtagaccca
     1741 aacaaattgg tcgctttgat agagattaaa ccagcttagg tccatcccaa tcagtagaaa
     1801 tacactgact aataaagcta tgaccactac ataataaatc actttatact tgttcatcac
     1861 tcgtcctcct ccaaacgaaa taccgattcg actgtttcgt tgaaaatttg agatattttc
     1921 agggcaatga taatggatgg ggtgtactca tcccgttcta gtaggctaat ggtctgtctg
     1981 gaaacccctg ccagtttggc taggtcggtt tgattgagac catcgcgagc tctaagctct
     2041 tttagacgat ttttaagttg catgttacac acctactctc cgtcaaattc aacggtttgg
     2101 atatcctcaa tgcgttgcaa cttgaatttt tcttttcccg tattatctac acgtcgtagc
     2161 tttacccatt cctcatcaac atccacaact tcccagttat ctggcccaat atacactccc
     2221 gttataattg gttcctttcc aatcatttct tgaaataatc tcgacatttc tgcgtttcct
     2281 ttctcttttc gctcaagttt tttgatttta ttctctagtt tcttgatttt tttagaatta
     2341 ttagaataaa agaaaatcat aaatagtata aatcctagta cccacatcat agctcctttc
     2401 ttcttttctc ttaacttgct tacatcgtaa cacatctttt tctttttgac aagtatagtt
     2461 gtcaaaaagt ttatgatttt tgtcattttg caaaggaaaa aggtcaggag taagttcctg
     2521 accactttat ctatcattaa tactcttcta aaatctcttc aaaccacgtc agcttcatct
     2581 acaacctcaa aaccatgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
     2641 ttcattgagt ataaaatcct agtttttcaa agatttctga gaagttttgg ctgattgtct
     2701 caagtgacac ttgcacttct tctcgggttt ggttgttctt gaccgtcact tgtccgcttt
     2761 cgacttcgct ctctcctagg gtgatgaggg tcttagccgc aaagacatct gctgacttga
     2821 actgagcttt gagcttacgg ttgaggtaat cacgctctgc tttgaaacct tgttggcgaa
     2881 gagcttggac tagttctagg gctttgacat ttgctccatc acccaagact gcgatataga
     2941 catctagggc gttttcgata gggagggcca cgccttgttt ttcaaggatg agaagcaggc
     3001 gctctacacc aagcccaaaa ccaaatccag cagtttcagg gcctccaaag taagcaacca
     3061 aaccatcgta gcgaccaccc gcacagactg tcaagtcatt gccctcaatc tctgtgataa
     3121 actcgaaaat ggtgtggttg tagtagtcca gaccacgcac catattggta tcgatgatgt
     3181 aatctactcc aagattttcc aacatctgac gcacagcatc aaaatgagtt tggctttctt
     3241 catcaagaaa gtccaagata gacggcgcat tctctactgc caccttgtct tctttttcct
     3301 tagagtccaa gacacgaaga ggattttcct ccaagcgacg ttggctatcc ttagacaagg
     3361 tctccttgag cggtgtcaaa tagtcaatca aggcttggcg gtaggctgca cggctctcag
     3421 gatttccaag agtgttgagg tgcaatttga caccttgaat accgatttcc ttcaaaaaat
     3481 aggctgccat agagattgtt tccacatcgg tagctggatt gctagagcca aaacactcaa
     3541 caccaatctg gtggaattgg cgcaagcgcc ctgcctgtgg acgctcataa cggaacatag
     3601 gtcccatata gtagaacttg cttggctttt gcacttctgg ggcgaagagt ttattttcca
     3661 cataggaacg gacaacgggc gcagttcctt ctggacggag ggtaatatga cggtcaccct
     3721 tgtcataaaa atcgtacatt tccttggtta cgatatccgt tgtatctccg acagagcgac
     3781 tgataacctc gtaatgctca aaaataggcg tgcgcacttc tgcatagtta tagcgcttga
     3841 aaatctcacg ggcaaagccc tcaacgtact gccacttagc agattcagca ggtaaaatat
     3901 cctgcgttcc ttttggtttt tgtaatttca tagggaatcc tctttaaact taatagtctt
     3961 attttaccac aaataaaggg attaaaacag taagaaaaaa attaggattt agatatcatt
     4021 tttgagatta agaattgtca aaaaaatagc tagcaaggaa agaccaacaa atagcatcca
     4081 agtcaactgt atattccata cggctactag tgaaaaacaa gctgttccca caggtatgga
     4141 taaggtaaac aatagaccta aaaaattact agtacgagct agaacctctg gagctagatt
     4201 tttcatgagc atggcactaa tctttggttg aactttacca gacacataca gggtaaagaa
     4261 gagaaatagc aaaccaagca cgacttgatt gaataaatta gccaaaccaa ctagactaag
     4321 tcctacggtc gcccacatca tcaatctagg caaggactgc ttcccaaaat aatcattgcc
     4381 cgtaaggcta ctgatgatga ttgctactaa aacacagaat tgattgataa atagtgcctc
     4441 tgtataagaa aaattcaaga gagaatggct caaaaagaag atattataaa ttccacccaa
     4501 agcgccaccc aaggaattaa taagcaagac agcaaagagc ataaaaccaa agtttttctg
     4561 cccactttta agaaaaacga gacgtaaatt tcggtaaatt gttaggaact ggtctttgat
     4621 agaaagcttc tcatttttta agttttcacc atcagcagat gacattgaca ggctcaattt
     4681 gctttttcct aaaaagagga tagtggctga tactaggaaa aagcaggcat tgattcccgc
     4741 aacgagagaa aaattgttga ccgatagagc taagagccag actccgaaag cttgaccacc
     4801 aatagctgaa atataggtga tgaactgtga aaaagaataa gcctccatca gatcatcttc
     4861 agctactttt tccttaataa gaggcatgcg caagccacct gcaaaatcac tgatgacatc
     4921 actaatgaca ttgatcaaac acaggctaga aaaggcaaag agactagctt gctgaacaac
     4981 tagggctgct aggaaaaata gaaccgcctg aaacaaaccg ctatagacca tccatttgac
     5041 cttgtccctc gtgtaatctg cccgaatccc tacaaaaact gtaaagaggg tcggaagaat
     5101 catgacaata ttcgccatag caacagcaaa agatgcttgt gacaaggtcg atgcatagac
     5161 gataaagacc aggttgaaaa tcgaagcacc aaaagcattg aagaagcgtg ataaagtcaa
     5221 aattctataa gctggatttc taaacaatag tttcatagat aatctccctt cttgttctaa
     5281 gttctacatc aagaatagct ttag
//
LOCUS       DBEJJV010000072         5055 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.072, whole genome shotgun sequence.
ACCESSION   DBEJJV010000072 DBEJJV010000000
VERSION     DBEJJV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 5055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5055
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.072"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            185..1730
                     /locus_tag="ACL3GT_002052"
     rRNA            185..1730
                     /locus_tag="ACL3GT_002052"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1782..1854
                     /locus_tag="ACL3GT_002053"
     tRNA            1782..1854
                     /locus_tag="ACL3GT_002053"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1815..1817,aa:Ala,seq:tgc)
     gene            1979..4880
                     /locus_tag="ACL3GT_002054"
     rRNA            1979..4880
                     /locus_tag="ACL3GT_002054"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4957..>5055
                     /gene="rrf"
                     /locus_tag="ACL3GT_002055"
     rRNA            4957..>5055
                     /gene="rrf"
                     /locus_tag="ACL3GT_002055"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1425 a         1024 c         1487 g         1119 t
ORIGIN      
        1 gttgacaagt gaaagtggct gtgatatact aatatagttg tcgcttgaga gaagcaagtg
       61 acaaagacct ttgaaaactg aacaagacga accaatgtgc agggcgctac aacataagtt
      121 gtagtactga acaatgaaaa aacaataaat ctgtcagtga cagaaatgag taagaactca
      181 aacttttaat gagagtttga tcctggctca ggacgaacgc tggcggcgtg cctaatacat
      241 gcaagtagaa cgctgaagga ggagcttgct tctctggatg agttgcgaac gggtgagtaa
      301 cgcgtaggta acctgcctgg tagcggggga taactattgg aaacgatagc taataccgca
      361 taagagtaga tgttgcatga catttgctta aaaggtgcac ttgcatcact accagatgga
      421 cctgcgttgt attagctagt tggtggggta agggctcacc aaggcgacga tacatagccg
      481 acctgagagg gtgatcggcc acactgggac tgagacacgg cccagactcc tacgggaggc
      541 agcagtaggg aatcttcggc aatggacgga agtctgaccg agcaacgccg cgtgagtgaa
      601 gaaggttttc ggatcgtaaa gctctgttgt aagagaagaa cgagtgtgag agtggaaagt
      661 tcacactgtg acggtatctt accagaaagg gacggctaac tacgtgccag cagccgcggt
      721 aatacgtagg tcccgagcgt tgtccggatt tattgggcgt aaagcgagcg caggcggtta
      781 gataagtctg aagttaaagg ctgtggctta accatagtag gctttggaaa ctgtttaact
      841 tgagtgcaag aggggagagt ggaattccat gtgtagcggt gaaatgcgta gatatatgga
      901 ggaacaccgg tggcgaaagc ggctctctgg cttgtaactg acgctgaggc tcgaaagcgt
      961 ggggagcaaa caggattaga taccctggta gtccacgctg taaacgatga gtgctaggtg
     1021 ttagaccctt tccggggttt agtgccgtag ctaacgcatt aagcactccg cctggggagt
     1081 acgaccgcaa ggttgaaact caaaggaatt gacgggggcc cgcacaagcg gtggagcatg
     1141 tggtttaatt cgaagcaacg cgaagaacct taccaggtct tgacatccct ctgaccgctc
     1201 tagagataga gttttccttc gggacagagg tgacaggtgg tgcatggttg tcgtcagctc
     1261 gtgtcgtgag atgttgggtt aagtcccgca acgagcgcaa cccctattgt tagttgccat
     1321 catttagttg ggcactctag cgagactgcc ggtaataaac cggaggaagg tggggatgac
     1381 gtcaaatcat catgcccctt atgacctggg ctacacacgt gctacaatgg ctggtacaac
     1441 gagtcgcaag ccggtgacgg caagctaatc tcttaaagcc agtctcagtt cggattgtag
     1501 gctgcaactc gcctacatga agtcggaatc gctagtaatc gcggatcagc acgccgcggt
     1561 gaatacgttc ccgggccttg tacacaccgc ccgtcacacc acgagagttt gtaacacccg
     1621 aagtcggtga ggtaaccgta aggagccagc cgcctaaggt gggatagatg attggggtga
     1681 agtcgtaaca aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggataa
     1741 ggaactgcgc attggtcttg tttagtcttg agaggtcttg tggggcctta gctcagctgg
     1801 gagagcgcct gctttgcacg caggaggtca gcggttcgat cccgctaggc tccattggtg
     1861 agagatcacc aagtaatgca cattgaaaat tgaatatcta tatcaaatag taacaagaaa
     1921 ataaaccgaa aacgctgtag tattaataag agtttatgac tgaaaggtca gaaaataagg
     1981 ttaagttaat aagggcgcac ggtggatgcc ttggcactag gagccgacga aggacgtgac
     2041 aaacgacgat atgccttggg tagctgtaag taagcgatga tccagggatt tccgaatggg
     2101 ggaacccaac aggtaatacc tgttacctac atctgttaag gatgtgagga ggaagacgca
     2161 gtgaactgaa acatctaagt agctgcagga agagaaagca aaagcgattg ccttagtagc
     2221 ggcgagcgaa acggcagaag ggcaaaccga agagtttact cttcggggtt gtaggactgc
     2281 aatgtggact caaagattat agaagaatga tttgggaaga tcagccaaag agagtaatag
     2341 cctcgtattt aaaatagtct ttgtacttag cagtatcctg agtacggcgg gacacgtgaa
     2401 atcccgtcgg aatctgggag gaccatctcc caaccctaaa tactccctag tgaccgatag
     2461 tgaaccagta ccgtgaggga aaggtgaaaa gcaccccggg aggggagtga aatagaacct
     2521 gaaaccgtgt gcctacaaca agttcgagcc cgttaatggg tgagagcgtg ccttttgtag
     2581 aatgaaccgg cgagttacgt tatgatgcga ggttaagttg aagagacgga gccgtaggga
     2641 aaccgagtct gaatagggcg ccttagtatc atgacgtaga cccgaaacca tgtgacctac
     2701 ccatgagcag gttgaaggtg cggtaagacg cactggagga ccgaaccagg gcacgttgaa
     2761 aagtgcttgg atgacttgtg ggtagcggag aaattccaaa cgaacttgga gatagctggt
     2821 tctctccgaa atagctttag ggctagcgtc gacattagag attcttggag gtagagcact
     2881 gtttgggtga ggggtccatc ccggattacc aatctcagat aaactccgaa tgccaatgaa
     2941 ttatggtcgg cagtcagact gcgagtgcta agatccgtag tcgaaaggga aacagcccag
     3001 accaccagct aaggtcccaa aataattgtt aagtggaaaa ggatgtgggg ttgcacagac
     3061 aactaggatg ttagcttaga agcagctatt cattcaaaga gtgcgtaata gctcactagt
     3121 cgagtgaccc tgcgccgaaa atgtaccggg gctaaaacaa tttaccgaag ctgtggatac
     3181 ctttataggt atggtaggag agcgttctat gtgtgatgaa ggtataccgt gaggagtgct
     3241 ggaacgcata gaagtgagaa tgccggtatg agtagcgaaa gacaggtgag aatcctgtcc
     3301 accgtaagac taaggtttcc aggggaaggc tcgtccgccc tgggttagtc gggacctaag
     3361 gagagaccga aaggtgtatc cgatggacaa caggttgata ttcctgtact agagtatgta
     3421 gtgatggagg gacgcagtag gctaactaaa gcagacgatt ggaagagtct gtctaagcag
     3481 tgaggtgtga attgagtcaa atgcttaatt ctataacatt gagctgtgat ggggagcgaa
     3541 gtttagtagc gaagttagtg acgtcacact gccaagaaaa gcttctagcg tttaaacata
     3601 ctctacccgt accgcaaacc gacacaggta gtcgaggcga gtagcctcag gtgagcgaga
     3661 gaactctcgt taaggaactc ggcaaaatga ccccgtaact tcgggagaag gggtgctgac
     3721 ttaaagtcag ccgcagtgaa taggcccaag caactgttta tcaaaaacac agctctctgc
     3781 taaatcgtaa gatgatgtat agggggtgac gcctgcccgg tgctggaagg ttaagaggag
     3841 tgcttagcgt aagcgaaggt atgaattgaa gccccagtaa acggcggccg taactataac
     3901 ggtcctaagg tagcgaaatt ccttgtcggg taagttccga cccgcacgaa aggcgtaatg
     3961 atttgggcac tgtctcaacg agagactcgg tgaaatttta gtacctgtga agatgcaggt
     4021 tacccgcgac aggacggaaa gaccccatgg agctttactg cagtttgata ttgagtgtct
     4081 gtaccacatg tacaggatag gtaggagtct aagagatcgg gacgccagtt tcgaaggaga
     4141 cgctgttggg atactaccct tgtgttatgg ccactctaac ccagataggt gatccctatc
     4201 ggagacagtg tctgacgggc agtttgactg gggcggtcgc ctcctaaaag gtaacggagg
     4261 cgcccaaagg ttccctcaga atggttggaa atcattcgca gagtgtaaag gtataaggga
     4321 gcttgactgc gagagctaca actcgagcag ggacgaaagt cgggcttagt gatccggtgg
     4381 ttccgtatgg aagggccatc gctcaacgga taaaagctac cctggggata acaggcttat
     4441 ctcccccaag agttcacatc gacggggagg tttggcacct cgatgtcggc tcgtcgcatc
     4501 ctggggctgt agtcggtccc aagggttggg ctgttcgccc attaaagcgg cacgcgagct
     4561 gggttcagaa cgtcgtgaga cagttcggtc cctatccgtc gcgggcgtag gaaatttgag
     4621 aggatctgct cctagtacga gaggaccaga gtggacttac cgctggtgta ccagttgtct
     4681 tgccaaaggc atcgctgggt agctatgtag ggaagggata aacgctgaaa gcatctaagt
     4741 gtgaaaccca cctcaagatg agatttccca tgattatata tcagtaagag ccctgagaga
     4801 tgatcaggta gataggttag aagtggaagt gtggcgacac atgtagcgga ctaatactaa
     4861 tagctcgagg acttatccaa agtaactgag aatatgaaag cgaacggttt tcttaagttg
     4921 aatagatatt caattttgag taggtattac tcagagttaa gtgacgatag cctaggagat
     4981 acacctgtac ccatgccgaa cacagaagtt aagccctaga acgccggaag tagttggggg
     5041 ttgccccctg tgaga
//
LOCUS       DBEJJV010000073         4572 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.073, whole genome shotgun sequence.
ACCESSION   DBEJJV010000073 DBEJJV010000000
VERSION     DBEJJV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4572
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.073"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(58..1068)
                     /locus_tag="ACL3GT_002056"
     CDS             complement(58..1068)
                     /locus_tag="ACL3GT_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HGR0517645.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1217..2386
                     /locus_tag="ACL3GT_002057"
     CDS             1217..2386
                     /locus_tag="ACL3GT_002057"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HGR0517646.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2383..3153
                     /gene="recO"
                     /locus_tag="ACL3GT_002058"
     CDS             2383..3153
                     /gene="recO"
                     /locus_tag="ACL3GT_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HGR0517647.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3150..4142
                     /gene="plsX"
                     /locus_tag="ACL3GT_002059"
     CDS             3150..4142
                     /gene="plsX"
                     /locus_tag="ACL3GT_002059"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HGR0517648.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4148..4381
                     /locus_tag="ACL3GT_002060"
     CDS             4148..4381
                     /locus_tag="ACL3GT_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HGR0517649.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4427..4572
                     /locus_tag="ACL3GT_002061"
                     /pseudo
     CDS             4427..4572
                     /locus_tag="ACL3GT_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         1340 a          878 c         1163 g         1191 t
ORIGIN      
        1 aacatatacc tacggcaagg cgacgttgac gtggtttgaa gagattttcg aagagtgtta
       61 gaaaatgccg ataagggtct gcataccaag agtggtgagg atgatggcaa tccagcagat
      121 ggctccaaga acaatggatt ttccactgga tttgaccata gcgaccagat tggttttgag
      181 accgatagca ctcatggcca tgacaataag gaatttagag agttgtttga gaggggtaaa
      241 gaaactactg gacacaccta gagaggtgag tagtgtagtg aggagagagg caaggataaa
      301 gtaaaggata aaaagtggga agactttttt cagttgtagg ctttgcttgt tttcttgttg
      361 gcgactttgc cagtaggata gaaagagcgt gatagggata atggccaaag tacgtgtgag
      421 tttaacaatg gttgcagact cgagggtatt gctttggtaa agactgtccc aagcgctggc
      481 ggcagccgtt acagaggaag tgtcgttgac cgcagtccct gcaaagaggg cgaagccttc
      541 attggataga tgaagccagg tgccgagggt tggaaagatg agcgcagcca agacattgaa
      601 gaaaaagata acggaaatgg cttgggctac ttccttttcc ttagcatgga taacaggcgc
      661 tgtcgctgca atggcagaac ccccacagat agaagaacct actccaacca aggtagccag
      721 ttttgtatcc agtgcaaaga aacgctggaa gaggtaggca ataatcagag ctattgagat
      781 agtggacagg atgacaggga gtgaagattg gccaactgcg aagacctgcg agatattgag
      841 accaaaacca agcaagacaa cggcatattg gagcaacttc ttggaactaa aggtcaaacc
      901 agcatccagt tgtttatagg acgagagaaa gggatgtagg agcatgccta tgaaaatggc
      961 aaaaacgggc gcgccaatca cagggaagaa tcctcctaag taccaagata ggatggaaat
     1021 gagaaggcag gccaagatac ctgctccatt ttttgataga aatgacataa aaacctccaa
     1081 ataaaatcta ttaccattat agacctataa acaggaaaag taaaatagaa agtggaaagc
     1141 tattctctaa tgtatttttg cggtcggggg gcttttgtag tataatagag atacgttttg
     1201 aaagtaggag gtatctatgg acttaactaa gcgctttaat aaacagttag ataaaattca
     1261 agtttcgttg attcgtcagt ttgaccaggt tatttcggag attcctgggg tcttgcgttt
     1321 gaccttgggg gaacctgatt ttacaacgcc agaccatgtc aaggaggcgg ccaagcgagc
     1381 gattgatcag aaccaatcct actatacagg gatgagtggt ctgctgactc tacgtcaggc
     1441 agccagtgac tttgttaagg aaaagtacca actggactat gctcctgaaa atgaaatctt
     1501 ggttacaatt ggggcgacag aggctttatc tgcgactttg acggctattt tggaagaggg
     1561 agacaaggta cttttgccag ctcctgctta tccaggctat gaaccgattg ttaacttagt
     1621 tggggcagaa attgttgaga ttgatacgac tgaaaatggt tttgtcttga ctcctgagat
     1681 gttggagaag gccattttgg agcagggtga taagctcaag gcggttattc tcaactatcc
     1741 agccaatccg acaggaatta cctacagtcg agagcagtta gaggccttgg cagctgtttt
     1801 acgcaagtac gaaatttttg ttgtctgtga tgaggtttac tcagaattga cctacacagg
     1861 cgaagcccat gtgtctctag gaacgatgtt gagagaccag gctattatta tcaatggttt
     1921 gtctaaatcg catgccatga caggttggcg tttggggctg attttcgctc ctgcgacctt
     1981 cacagcccag ttaatcaaga gtcaccagta cttggtcact gccgcaaata ccatggcgca
     2041 acatgctgca gtagaagcct tgacggctgg taaaaacgat gcggagccca tgaagaagga
     2101 atatatccaa cgtcgggact atatcatcga aaaaatgact gctcttggtt ttgagattat
     2161 caaaccagac ggtgccttct atatttttgc taaaattcca gcgggctaca atcaagactc
     2221 ctttgctttt ctgaaggatt ttgctcagaa gaaggccgtt gcctttatcc ctggtgcagc
     2281 ctttggacgt tacggggaag gctacgtccg cctatcttat gcagccagca tggagactat
     2341 caaagaagcc atgaaacgac ttgaggagta catgagagaa gcatgattca gtctatcacg
     2401 agtcaaggct tggtgcttta caatcgcaat tttcgtgagg atgacaagct cgtcaaaatt
     2461 tttacagagc aggttggcaa acgcatgttt tttgtcaaac acgctggtca gtctaagctg
     2521 gcgcctgtta ttcagccctt ggtgctggca cgatttctct tgcgaatcaa tgatgacgga
     2581 ctcagttaca tcgaagacta tcatgaggtc atgacttttc ccaagattaa tagtgacctc
     2641 tttgtcatgg cctatgcgac ctatgtggca gctcttgcag atgctagttt gcaggacaat
     2701 cagcaggatg ctcccttgtt tgcttttttg caaaagactt tggagttgat ggaagcaggc
     2761 ttggattatc aggttttgac caatattttt gaaattcaaa ttttgactcg atttggaatc
     2821 agcctcaatt ttaatgagtg tgtcttctgc catcgggttg gtcaggcttt tgacttttct
     2881 ttcaaatatg gagcctgcct ctgtccagag cattatcatg aggataagag acgttgtcat
     2941 ctcaatccca atatccccta tctgctcaat caatttcaag ctattgattt tgagactttg
     3001 gagaccattt cgctcaagcc tggaatcaag caagagctac gccaatttat ggatcaacta
     3061 tatgaagagt acgttgggat tcacctaaaa tcaaagaaat ttattgattc cctagcagac
     3121 tggggacaat tactaaaaga ggaaaagaaa tgaaaaaaat cgcagtagat gccatggggg
     3181 gcgattacgc acctcaggcc attgttgagg gtgtcaatca agccctatct gacttttcag
     3241 atatcgaggt tcaactttac ggagatgaag ctaaaatcaa gcaatatctg acagcgacag
     3301 agcgcgtcag cattatccat acggatgaga agattgattc ggatgatgaa cctacgagag
     3361 ctattaggaa taagaaaaat gccagtatgg tattggcagc caaggctgtc aaagatggtg
     3421 aagcagacgc tgtcctttcg gctgggaata caggtgcctt gttggcagca ggattcttca
     3481 tcgtgggtcg tatcaagaat atcgaccgtc ctggactcat gtctaccttg cctaccgttg
     3541 atggaaaagg ttttgacatg ctagaccttg gtgctaatgc agaaaataca gcccagcacc
     3601 tccatcaata tgcggttcta ggttccttct atgctaaaaa tgtccgtggc attgcgcaac
     3661 cacgcgttgg tttgctcaac aacggaacag agagtagcaa gggcgacccg cttcgtaagg
     3721 aaacttatga attactggcg gctgatgaaa gtttgaactt tatcggaaac gtggaagcgc
     3781 gtgatttgat gaatggcgtt gcagatgttg ttgtggcaga tggtttcacg ggaaacgctg
     3841 tgctcaaatc catcgaaggg acagctatgg gaatcatggg cttgctcaag acagctatta
     3901 caggtggtgg tcttcgagcg aaactaggtg ccctccttct caaggacagc ctcagtggtt
     3961 tgaaaaaaca gctcaattat tcagatgttg gtggagcggt cttgtttggt gttaaagcac
     4021 ctgttgtcaa gactcatggc tcaagcgatg ccaaggctgt ttatagtacg attcgtcaga
     4081 tccgtaccat gctagaaaca gacgtggttg cccagactgc gcgtgaattt tcaggagaat
     4141 aaaagagatg acagaaaaag aaatttttga ccgtattgtg accattatcc aagagcgaca
     4201 gggagaggac tttgtcgtga cagaatcctt gagtctgaaa gacgatttgg atgcggattc
     4261 tgttgacttg atggagttta tcttgactct ggaagatgaa tttagtatcg aaatcagcga
     4321 tgaagaaatt gaccaactcc aaaacgtagg agatgtggtt aaaatcattc aaggaaaata
     4381 gtaatcggag ttccaagtca acggaagtag atggttttta gaaatgagaa atatcggaca
     4441 agctggtaaa atcttggctg acagtggtta tcaagggctc atgaagatat atcttcaagc
     4501 acaaactcca cgtaaatcca gcaaactcaa gccgctaaca gctgaagata aagcctataa
     4561 ccatgcgcta tc
//
LOCUS       DBEJJV010000074         4485 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.074, whole genome shotgun sequence.
ACCESSION   DBEJJV010000074 DBEJJV010000000
VERSION     DBEJJV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.074"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(55..962)
                     /locus_tag="ACL3GT_002062"
                     /pseudo
     CDS             complement(55..962)
                     /locus_tag="ACL3GT_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603324.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            1218..3851
                     /gene="polA"
                     /locus_tag="ACL3GT_002063"
     CDS             1218..3851
                     /gene="polA"
                     /locus_tag="ACL3GT_002063"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HGR0517650.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEYGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPDIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3936..4373
                     /locus_tag="ACL3GT_002064"
     CDS             3936..4373
                     /locus_tag="ACL3GT_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HGR0517651.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
BASE COUNT         1221 a          833 c         1079 g         1352 t
ORIGIN      
        1 aggctccata atatccatag gggatttacc cactatggat attatggagc cattttacaa
       61 cagtgcctca aattcagata ctgacatacc taattgctgg ctggcaacct cagaagtcag
      121 aagaccttgg cgtactatgt ctaggaaggc aaaaagtttc ctttctgccc ttccttcaac
      181 tttcccacgc tctagtcctt gttcaaggcc ttcagcccta gcagtttcca aggcatagtc
      241 ctgtgctaac aagacttgtt cttctcgcat atgtagttga ctaaacattt tcctgtcctc
      301 ctcggaccag ctcttgtagt ccagcagttg atttgcttgg ctaatggctc gttgcggttg
      361 ctgggtaaag ggcttgttgc cgaaaaactc caaccatggc ttgcgaacct tgtctttgct
      421 ggtttctctg tattttttaa ttccaagaat gccatcttaa ccagatggtt ttcctgtcca
      481 ttgttggtaa tcgccaatac ctcacctgtt gtgtcttcgc gcatactaaa gctatgaaaa
      541 gccaggtcat ctgagaaata attactatcc acgatagcaa tggcgtaaac aggagcgatg
      601 tgtttgtagc tctagtgagt atcaccttct cgctgacgaa ttttttcaag attttgatta
      661 acctgactgc acaggtaagt ccacaagtga ttgatgaaaa aattctgatg atggacttga
      721 atctcaataa ttacttgagt accgttatcc aactccgcca agacgtctat actggtataa
      781 aaatcctgca ccgagtaagg catggagagt aatacgtgaa tatcgcttcc ctccaaaatg
      841 gtcacatttt ttgctggcaa gtccagcata tcgcgaataa attgacaagt gatttctgga
      901 ttgctgaata ttttcttagc aatcaaatca ttagttgggc tgatgcccgg atgtctgaga
      961 atcctcctat tcctccttct atagtgagtt gaaataagat gtgaataact ctatcaggaa
     1021 agtcaaatta atttatagaa atattttagc agtcaaggtg tactattata gattcaatat
     1081 attatattat agcacatttt taaatctagg tttactaaat tctctggctc tatctattta
     1141 ttcggaaaaa gtttgaaaaa tacttgctct agctcttccc aatggtattt tttgattctt
     1201 tcctttataa tgggtgtatg gataagaaaa aattattatt gattgatggg tcttctgtag
     1261 cttttcgggc gttttttgcg ctgtatcagc agttggaccg ttttaagaat gcggctggtt
     1321 tgcataccaa tgcgatttat ggttttcagt tgatgttgag tcatttgttg gagcgggttg
     1381 agccgagtca tattttggtg gcttttgatg cgggaaagac gaccttccgg acagagatgt
     1441 atgcggacta taagggtggt cgggccaaga ctcctgatga gtttcgtgag caatttcctt
     1501 tcattcgtga gttgctggat catatgggga ttcgtcacta tgagctggct cagtatgagg
     1561 cggatgacat cattgggacg ctggataagc tagcagagca ggatggtttt gatattacca
     1621 ttgtcagtgg ggacaaggat ttgattcagc tgacggatga gcatacggtg gttgaaattt
     1681 ccaagaaagg tgtggctgag tttgaggcct ttacgccaga ttacctcatg gaagaaatgg
     1741 gcctcacacc agctcagttt atcgatctca aggcgctcat gggtgataag tcggataata
     1801 tccctggggt gaccaaagtc ggtgaaaaga cgggtattaa gctcttgctg gagtatggtt
     1861 cgcttgaggg gatttatgaa aatattgatg gaatgaagac ttctaagatg aaggaaaatc
     1921 tcatcaatga caaggaacag gcctttttgt ctaaaacact agcgaccatt gataccaagg
     1981 caccgattgc gattggttta gaggacttgg tctatagtgg tccagatgtt gaaaatcttg
     2041 ggaaatttta cgatgagatg ggattcaaac agctcaagca ggctttaaat gtgtcgtcag
     2101 ctgatgtggc taagggtttg gattttacta ttgttgacca aatcagtcaa gatatgctga
     2161 gtgaagagtc tatcttccac tttgagcttt ttggtgagaa ttaccatacg gataatttgg
     2221 ttggatttgc ctggtcttgt gaggataagc tctatgccac agacaagctt gagctgttgc
     2281 aagacccgat tttcaaggat ttcttagaaa aaacatctct gagagtttat gactttaaga
     2341 aggttaaagt tcttttgcaa cgttttggtg tggatttgca ggcgcctgct tttgacatcc
     2401 gtttggctaa atacctcctt tcgactgtgg aggacaatga aattgcgacc atcgctagtc
     2461 tttatggtca gacttacttg gttgatgatg aaactttcta cggtaagggt gttaaaaagg
     2521 ccattcctga acgtgagaaa ttcttggaac acttagcttg taaacttgct gttttggtag
     2581 aaacagagcc tattttactt gaaaaactca gcgaaaatgg gcaattagag cttctttatg
     2641 atatggagca acctctggct tttgttcttg ccaagatgga aattgctggg attgtggtca
     2701 agaaagagac cttgcttgag atgcaggctg aaaatgagct tgtcattgaa aaactgactc
     2761 aagagattta cgagctggct ggtgaggagt ttaatgtcaa ctcgcctaag cagttgggcg
     2821 tgcttctctt tgagaaattg ggacttcctc tagaatacac taagaaaacc aagacaggtt
     2881 attcgacagc agtggatgtg ttggagcgtc tcgctcctat tgctccgatt gttaagaaaa
     2941 tcctggatta ccgtcaaatt gctaagattc aatctactta tgtaattggc ttgcaggact
     3001 ggattttggc tgatggaaag attcatactc gctatatgca ggatttgacc cagaccgggc
     3061 gtttgtctag tgtggatcca aacttgcaaa atattcctgc ccgattggaa caagggcgct
     3121 tgattcggaa ggcttttgtg ccagagtggg aggatagtgt gctactcagc tctgactatt
     3181 cacagattga attgcgcgtt ttggcgcata tttctaagga tgagcacttg attaaggcct
     3241 tccaagaggg ggcagatatc catacttcga cagccatgcg ggtctttggc attgagcgtc
     3301 ctgataatgt gactgcaaat gaccgtcgca atgccaaggc agttaacttt ggagtggttt
     3361 atgggatttc agactttggc ttgtctaata atttgggaat tagtcgtaag gaagccaaag
     3421 cctacattga tacctacttt gaacgttttc cagatattaa aaactacatg gatgaagtgg
     3481 tgcgggaggc gcgtgataag ggctatgtag agaccctctt taagcgtcgc cgtgagttgc
     3541 cagatatcaa ttcgcgcaac ttcaatattc gtggttttgc ggagcgaact gctatcaact
     3601 cacctatcca gggttcggca gcagatattc tcaagattgc catgattcag ctggataaag
     3661 ccttggttgc aggtggttat cagactaaga tgctgttaca agtgcacgat gaaatcgtcc
     3721 ttgaagtgcc taaatctgaa ttggtagaga tgaaaaaatt ggtgaaacaa accatggaag
     3781 aagccattca actcagtgtt cctcttatcg cagatgagaa tgaaggggca acctggtacg
     3841 aggctaaata aaaagggggc tagtcctcct tttttgtagt ataattctgc aaaccttttc
     3901 aaaatgtgct atactgatga aaaaggagga tttctatgag tcaagaattt atcaatccaa
     3961 gtgatggcgt gattcgtcag tatctcgcaa cgagtaaaac ccttgctgtg gtgggtttgt
     4021 ctgaccgtga agaaacaacc agcaatcgag taacaaagga aatgcaggct cggggctata
     4081 aaatcatccc agtcaatccc aaggcggcag gtggcgaaat cttgggtgaa aaggcttatg
     4141 ctagcctcgc tgaaattcct tttcctgtag atattgtcaa tgtttatcgt cgcagtgaat
     4201 ttctgcccga tgtggcgcgt gattttctca aagctgatgc caagattttt tgggcacagc
     4261 taggacttga aagtttagaa gcgaaagaga ttttgcgtga tggtggatgt gatgatatcg
     4321 tgatgaatcg ctgtatcaag agagaacata ctcgcttgat tgaggaagca taagaaaaag
     4381 gtagctgatg ggctaccttt tgtgttatac tcaatgaaaa tcaaagagca cactagcaaa
     4441 ctaggaaact agccgcgggc tgctcaaaac accgttttga ggttg
//
LOCUS       DBEJJV010000075         4180 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.075, whole genome shotgun sequence.
ACCESSION   DBEJJV010000075 DBEJJV010000000
VERSION     DBEJJV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.075"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            118..363
                     /locus_tag="ACL3GT_002065"
     CDS             118..363
                     /locus_tag="ACL3GT_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517652.1"
                     /translation="MKAFYITIEKFIRDDESLKCYFTKVISSRSKVTSLDQIEADKTI
                     QRKYSSELKKFIGFYNEIICEENSFLHVRKRWSSWFR"
     gene            764..1756
                     /locus_tag="ACL3GT_002066"
     CDS             764..1756
                     /locus_tag="ACL3GT_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0517653.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQKIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1758..2576
                     /locus_tag="ACL3GT_002067"
     CDS             1758..2576
                     /locus_tag="ACL3GT_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0517654.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2578..3363
                     /locus_tag="ACL3GT_002068"
     CDS             2578..3363
                     /locus_tag="ACL3GT_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HGR0517655.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3461..3679
                     /locus_tag="ACL3GT_002069"
     CDS             3461..3679
                     /locus_tag="ACL3GT_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HGR0517656.1"
                     /translation="MKDLPEWFGIPESTQAYIEGTTTLQVWTAYQESDLTGFVRLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3664..3825
                     /locus_tag="ACL3GT_002070"
     CDS             3664..3825
                     /locus_tag="ACL3GT_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HGR0517657.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFSQLWNP"
BASE COUNT         1163 a          714 c          898 g         1405 t
ORIGIN      
        1 aattttactt tcccaatcga tttgttctca tcttatttca atccgctata tattatggta
       61 tcgaatcttc atcagaatga taaaattaat caattaatat ctgattacaa acagaatatg
      121 aaagcttttt atatcactat tgaaaaattt atacgagatg atgaaagcct taagtgttat
      181 tttacaaagg ttatttcaag tcgttccaag gtaacaagtc tagatcagat tgaagctgat
      241 aaaacgatac aaagaaaata ttcaagtgag ctaaaaaaat ttattggatt ttataatgag
      301 attatttgtg aggaaaatag tttcctacat gtacgaaaga ggtggtcgag ttggtttagg
      361 tagtcggtgc gtgagttgat aattctcagg gtatggactt ctttttcatg aatgaggtaa
      421 aagagcaggt attgtttaga gacaatcatt ctgagcatat tttctggata gagggagtat
      481 ccgattttat gatcaaagtt aataccgccc tctggtgaga agatgagtag gttggtaatt
      541 taaactatta aacagaattt ttgattaaaa gtattatttc atgagagaaa tcctaatttc
      601 acaatctata ggcaaacgct tgcatttcgt tttttattgg actataatag gttggtataa
      661 agccttctgt agtaataaaa tgtagaaggt gtagaaagta aggatttaga atatttgtag
      721 ttaaaaacac aatgttgcta ttccttacga tagggagata gatatggcaa tgatagaagt
      781 ggaacatctt cagaaacatt ttgtgaagat tgttaaggaa ccgggcttga agggggcttt
      841 gcgctccttt attcatcctg aaaagcagac ctttgaagcg gtcaaggatt tgacctttga
      901 ggttccaaaa gggcagattt taggatttat cggggcaaat ggtgctggga agtcgacaac
      961 cattaaaatg ctgacaggaa ttttgaaacc aacatctggt ttttgtcgga ttaacggcaa
     1021 gattccccag gacaatcggc aagattatgt caaagatatt ggcgtagtct ttggacaacg
     1081 cacccagcta tggtgggatt tggctctgca agagacctac actgtcttaa aagagattta
     1141 tgatgtgcca aactcgctct ttcataagcg tatggacttt ttgaatgaag tcttggattt
     1201 gaaggacttt atcaaggatc ccgtgcggac tctttcactg ggacaacgga tgcgagcgga
     1261 tattgcggcc tccttgctcc acaatcccaa ggttcttttt ttagatgagc cgaccattgg
     1321 tttggacgtt tcggttaagg ataatattcg tcgggcaatt actcagatca atcaagagga
     1381 agaaactacc attcttttga ccactcacga tttgagtgat attgagcaac tttgtgatcg
     1441 gattttcatg attgacaagg ggcaaaagat ttttgatgga acggtgagcc aactcaagga
     1501 gacctttggt aagatgaaga ctctctcttt tgaactgcta ccaggtcaaa gtcatctcgt
     1561 ctctcactat gaaggtctgt ctgatatgac cattgataga caaggaaaca gcctcaacat
     1621 tgaatttgat agttctcgct accagtcagc tgacattatc aagcaaaccc tatctgattt
     1681 tgaaatccgc gatttgaaga tggtggatac ggatattgag gatattatcc gtcgcttcta
     1741 ccgaaaggag ctctaggatg atcaaattgt ggagacgtta taaacccttt atcaatgcag
     1801 gggttcagga gttgattact taccgagtca actttattct ctatcggatt ggcgatgtca
     1861 tgggggcttt tgtggccttt tatctctgga aggctgtctt tgattcttcg caagagtctt
     1921 tgattcaggg cttcagtatg gcggatatca ccctctacat catcatgagt tttgtgacca
     1981 atcttctgac tagatccgat tcgtccttta tgattgggga ggaggtcaag gatggctcca
     2041 ttatcatgcg tttgttgcga ccagtgcatt ttgcggcctc ctatcttttc accgagcttg
     2101 gttccaagtg gttgattttt atcagcgttg gccttccatt tttaagtgtc attgtcttga
     2161 tgaaaatcat atcgggtcaa ggtattgtag aggtgctagg attaactgtc ctttatcttt
     2221 ttagcttaac gctcgcctat ctgattaact ttttctttaa tatttgcttt ggattttcag
     2281 cctttgtgtt taaaaatctt tggggttcca acctacttaa gacttccata gtggctttta
     2341 tgtcggggag tttgattccc ttggcattct ttccaaaggt tgtttcagat attctctcct
     2401 ttttgccttt ttcgtccttg atttatactc cagttatgat cattgttgga aaatacgatg
     2461 ccagtcagat tcttcaggca ctccttttgc agttcttctg gctcttagtg atggtgggat
     2521 tgtctcagtt aatttggaaa cgggtccagt cctttatcac cattcaagga ggttagtatg
     2581 aaaaaatatc aacgaatgca tctgattttt atcagacaat acatcaaaca aatcatggaa
     2641 tataaggtgg attttgtggt tggtgtcttg ggagtctttc tggctcaagg cttgaatctc
     2701 ttgtttctca atgtcatctt tcaacatatt ccattcctag aaggctggac ctttcaagag
     2761 atagctttca tttatggatt ttccttgatt cccaagggaa tggaccatct cttttttgac
     2821 aatctctggg cactagggca acgcctagtc cgaaaaggag agtttgacaa gtatctgact
     2881 cgtcccatca atcctctctt tcacatccta gttgaaacct ttcagattga tgccttgggt
     2941 gaactcttag tcggtggtat tttattggga acaacagtga ccagcattgt ttggactctt
     3001 ccaaaattcc tgcttttcct agtttgtatt ccttttgcga ccttgattta tacttctctt
     3061 aaaatcgcaa cagccagtat cgccttttgg actaagcagt caggcgccat gatttacatc
     3121 ttctatatgt tcaatgactt tgctaagtat ccgatttcta tttacaattc tcttcttcgt
     3181 tggttgatta gctttatcgt gcctttcgcc tttacagcct actatccagc tagctatttc
     3241 ttacaggaaa aggatgtgtt ctttaacgta ggaggtttga tgttgatttc tctggttttc
     3301 tttgttattt cccttaaact ttgggataag ggcttagatt cctacgaaag tgcgggttcg
     3361 taaaagctaa agtaagacta aaatcaagaa aggaacttat gatgtttgta attgaagaag
     3421 tcaaggatga aaatcaaaaa aggcagttgt cgttgaggtt ttgaaggatt tgccagaatg
     3481 gtttggaatc ccagaaagca cacaagccta tatagaagga accacgacac tgcaagtttg
     3541 gaccgcctat caggagagtg atttgactgg atttgtaagg ttatcctatt cgagtgaaga
     3601 ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa aattgggagc
     3661 caattgcttg ctactttaga gagtgaagct cgtaaaaaag ttggttatct gcaggtcaaa
     3721 acagtggcag aaggttctaa taaagattat gatcgaacaa atgactttta tcgaggtctt
     3781 ggctttaaaa agttagagat tttttctcag ctatggaatc cgtaaaatcc ttgtcagatt
     3841 ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgcc atactgtaag
     3901 tgtaatcgcc gatttagctc agttggtaga gcaaggcact cgtaaagcct aggttatagg
     3961 tagataaacg actgaggagt tgaaaaaata gataggtaga agataaccgt taagccttat
     4021 tcttagcggt tatttatatt gtttaatagc gctgatattt catcaattat gcctgttttc
     4081 gtgtttctgg tagttgttca agtttattgc tactattttt gatggtatga atgtgcttat
     4141 aatgtatccc ggttaacgaa agttttggac ttatactcat
//
LOCUS       DBEJJV010000076         4051 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.076, whole genome shotgun sequence.
ACCESSION   DBEJJV010000076 DBEJJV010000000
VERSION     DBEJJV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 4051)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4051)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4051
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.076"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            371..598
                     /locus_tag="ACL3GT_002071"
     CDS             371..598
                     /locus_tag="ACL3GT_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517658.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3768
                     /gene="nanA"
                     /locus_tag="ACL3GT_002072"
     CDS             886..3768
                     /gene="nanA"
                     /locus_tag="ACL3GT_002072"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HGR0517659.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKISRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYGNYNDAPLKVKPGQWNSVTFTVEKPTPE
                     LPKGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGVIG
                     LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQKIIGIAKGSIESM
                     HNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTK
                     EDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1381 a          670 c          886 g         1114 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacgctt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtgtaaatag cataggctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaatttggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gggagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaatttc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacggtaa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaaccg acaccagaac tacctaaagg ccgagtgcgc
     1561 ctctacgtaa acggggtatt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt acaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1741 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1801 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtaaccaat tactaggcaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgcca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 agacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaat
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaagatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gttattggct tggagtttga ctcagaagta
     3301 ttggtcaaca aggctccaac ccttcaattg gcaaatggta aaacagcgac tttcctaacc
     3361 cagtatgata gcaagacctt gttgtttgca gtagataagg aagatatcgg acagaaaatt
     3421 attggtatag ctaaaggaag catcgaaagt atgcataatc ttcctgtaaa tctagcaggt
     3481 gccagagttc ctggcggagt aaatggtagc aaagcagcgg tgcatgaagt tccagaattt
     3541 acagggggag ttaatggtac agagccagct gttcatgaaa tcgcagagta taagggatct
     3601 gattcgcttg taactcttac tacaaaagaa gattatactt acaaagctcc tcttgctcag
     3661 caggcacttc ctgaaacagg aaacaaggag agtgacctcc tagcttcact aggactaaca
     3721 gctttcttcc ttggtctgtt tacgctaggg aaaaagagag aacaataaga gaagaattct
     3781 aaacatttga ttttgtaaaa atagaaggag atagcaggtt ttcaagcctg ctatcttttt
     3841 ttgatgacat tcaggctgat acgaaatcat aagaggtctg aaactacttt cagagtagtc
     3901 tgttctataa aatatagtag attgaaataa gatgtgaaca actctatcag gaaagtcaaa
     3961 ttaatttata gaaaaatttt agtagtcaag gtgtactgtt atagattcaa tatattatgt
     4021 gactattaac cttgtcttct cctaaaattg a
//
LOCUS       DBEJJV010000077         3821 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.077, whole genome shotgun sequence.
ACCESSION   DBEJJV010000077 DBEJJV010000000
VERSION     DBEJJV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.077"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..418
                     /locus_tag="ACL3GT_002073"
     CDS             <1..418
                     /locus_tag="ACL3GT_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HGR0517660.1"
                     /translation="KNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            628..3747
                     /gene="phtE"
                     /locus_tag="ACL3GT_002074"
     CDS             628..3747
                     /gene="phtE"
                     /locus_tag="ACL3GT_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HGR0517661.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1430 a          627 c          750 g         1014 t
ORIGIN      
        1 taaaaataag gcagaccaag acagtaaacc tgatgaagat aagggacatg atgaagtaag
       61 tgagccaact caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc
      121 agataatctt tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac
      181 tacagatgag gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga
      241 tgcggaggcc ttgctagaaa aagtaacaga tcctagtatt agacaaaatg ctatggagac
      301 attgactggt ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc
      361 agaagtagat agtctcttgg ctttgttaaa aaaaagtcaa ccggctccta tacagtagta
      421 aaatgaatgg agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa
      481 aaacgtaaca gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta
      541 aatggttaaa taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac
      601 ttcatcattt attgaaatga gggatttatg aaatttagta aaaaatatat agcagctgga
      661 tcagctgtta tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag
      721 gaaaataagg acaataatcg tgtctcttat gtggatggca gccagtcaag tcagaaaagt
      781 gaaaacttga caccagacca ggttagccag aaagaaggaa ttcaggctga gcaaattgta
      841 atcaaaatta cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat
      901 gggaaagttc cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat
      961 caacttaaag acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat
     1021 ggaaaatatt atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat
     1081 gaaatcaatc gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt
     1141 gctgtagcaa ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct
     1201 gatattatcg aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac
     1261 attcccaaaa gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga
     1321 aaaaatatgc aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa
     1381 tctgtagcaa aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt
     1441 ttgaaggaac tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc
     1501 tttgaccctg ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac
     1561 cattaccact ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg
     1621 gtgcctatca gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg
     1681 tctagtctag gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct
     1741 tcagcatctg atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct
     1801 tatattgtaa gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa
     1861 ccgactcttc caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga
     1921 acttcacatg agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct
     1981 gaagatgaat caggttttgt catgagtcac ggagaccaca atcattattt cttcaagaag
     2041 gacttgacag aagagcaaat taaggctgcg caaaaacatt tagaggaagt taaaactagt
     2101 cataatggat tagattcttt gtcatctcat gaacaggatt atccaagtaa tgccaaagaa
     2161 atgaaagatt tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt
     2221 gtcaaacgtg aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga
     2281 gatcaccatc atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac
     2341 agtaactatg aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt
     2401 tatactggag aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat
     2461 caaaacttta ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg
     2521 gagaaaaaat taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg
     2581 gagaaagtat ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta
     2641 gatcaacctt atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca
     2701 gaagtaagtt atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt
     2761 caaacgattt tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt
     2821 gcagtgccta aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct
     2881 tatttagaaa ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa
     2941 ggaacaacca gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg
     3001 gacaatcaat cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat
     3061 aaaccaagta ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat
     3121 gaaaaggtag aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact
     3181 gggaatagta ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa
     3241 aaagtagcaa aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg
     3301 gacggaacaa ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat
     3361 tttacaggag aagcacctca aggaaatggt gaaaataaac catctgaaaa tggaaaagta
     3421 tctactggaa cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag
     3481 gcaccaaacg aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca
     3541 gaagggaatg tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta
     3601 gatcctgtac aagaaaaatt agaaaaattt acagctagtt acggattagg cttagatagt
     3661 gttatattca atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa
     3721 aagaatttat ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat
     3781 gaagttctct caaaagttag aaataaaact ctgactttgg g
//
LOCUS       DBEJJV010000078         3570 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.078, whole genome shotgun sequence.
ACCESSION   DBEJJV010000078 DBEJJV010000000
VERSION     DBEJJV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3570
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.078"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..270
                     /locus_tag="ACL3GT_002075"
     CDS             <1..270
                     /locus_tag="ACL3GT_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517662.1"
                     /translation="VTHYKYYRAENSHLIYADYFEMKLQKLLKDDTKVFEKSTFKFVE
                     GYKIYLTESKESGIKQMDNVIKYFEFIESKSIALYFQKRLNELID"
     gene            complement(628..1161)
                     /locus_tag="ACL3GT_002076"
     CDS             complement(628..1161)
                     /locus_tag="ACL3GT_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HGR0517663.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1250..2026)
                     /gene="recX"
                     /locus_tag="ACL3GT_002077"
     CDS             complement(1250..2026)
                     /gene="recX"
                     /locus_tag="ACL3GT_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HGR0517664.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2064..3419
                     /gene="rlmD"
                     /locus_tag="ACL3GT_002078"
     CDS             2064..3419
                     /gene="rlmD"
                     /locus_tag="ACL3GT_002078"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HGR0517665.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            3481..3552
                     /locus_tag="ACL3GT_002079"
     tRNA            3481..3552
                     /locus_tag="ACL3GT_002079"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3514..3516,aa:Glu,seq:ttc)
BASE COUNT         1167 a          605 c          638 g         1160 t
ORIGIN      
        1 gttacccact acaaatatta tagagccgaa aattcacatc taatatatgc agactacttt
       61 gaaatgaaat tacaaaaatt attaaaagat gacacaaaag tttttgaaaa atctacattc
      121 aaatttgtag aaggatataa aatatacctg acagaatcta aagaatctgg aattaaacaa
      181 atggacaatg tcataaaata ttttgagttt attgaatcta aaagtattgc tttatatttt
      241 caaaaacgat taaatgagct gatagattaa atatcatttt ctctgttaag atattgtttt
      301 taaaatattg tactaaatga ttgatgctat gtggaaatac aaaaaaatgt ttttgatacg
      361 aagttgacct gtatttttta tactaatcat tttcgtattt tttgtattaa acgatataag
      421 tttgttgtaa acttactagg aataaagaca ttaaaaaata atagtatatc tatttgtttt
      481 atatatttta cgaattctgc ataaatctct ttctagtaat gtgttgtaac tctgctataa
      541 tggatttatt cctttttgta tttacacaat ttattttata ctaccaaaaa aacaaggtca
      601 ggattttgtt cctgaccttt gacaacttta ccgattcttt agttctacat agcgcttgta
      661 ccaaatgttt acataggctt ctgagaaagg accacgtcca ttgttaatcc aatcaacaag
      721 aattttgaca tgttctttta aaatatagtc caagtcatca gaataattca ttttgcgttt
      781 gtgacgctcg tattcttcaa cgtccaagag acgtttttcc ccatctgtaa aaattttaac
      841 atccaaatcg taatcaatat acttcagtgc ttcttcatcc agatagtagg ggctagccat
      901 attgcaatag taagaagttc cattatcacg aatcatggca atgatattaa accaatattt
      961 cttgtgaaag taaacaatag ccggttctcg agtgacccaa cgacgaccat cactttcggt
     1021 aacaagtgta tgatcgttga caccaataat ggcgttttct gttgttttta gtaccatggt
     1081 gtcccgccaa gttcggtgga gactcccatc atgcttataa ctttgaattg taataaagtc
     1141 gccttctttt ggaagcttca taactaacca actttctaca atttataagt ttatcattta
     1201 ctattgtacc ataaaattac ctaaaatctg tgaatttcac ttggaaatat taaagatatt
     1261 ctctaagagc gcttgctata tccgaaaaat cgtagccctt tcgtgctaaa acttgagtta
     1321 aacgctgctt cagttcgtat ccttcatact ttcgagcata cttagtatat tgcttatcaa
     1381 gttccttgaa gatgagttct tgagtcgttt cttggtcaac ttggctatct aagtcgtcaa
     1441 aggcaatttt agcatcagaa taagagaagc ccttgttagt caagttctgg ataatcttat
     1501 cttgcagggc acgagctgga agttttccct catatttttt caatagttta ttggctacac
     1561 gttgagcaac ttcagaaaaa tcaaattctt tcaagttctc ttctatagta gattttgaaa
     1621 tccctttttg agatagtttc tgagtcagca cataaggacc cttgtctcct gaaagttgat
     1681 tggtattgat gatagcataa gcgtactgac catcattaat ccacttatct tctttaagat
     1741 tagcaataac ttgagaaacg atgtttttat caatatcgta ttttttcaga tattctctga
     1801 cttctttttc agtgcgtgct ttaaaggata agtggtagag agcgagattc ttaccataag
     1861 aaaattgagc aaagtcttga atctctttca attcctcttc gcttatcacc ttatctctcg
     1921 ataacataaa acgaacaatt gtatcttcgg tgatatagca tttgtcgcca ttatcaagct
     1981 ccatcaggta gagtcttttt ttcttttcaa gttttgtgat tttcatagct ctattataac
     2041 tcaaaatgtg ataagatagg ggtatgaatc tgaaagtgaa acaaaaaata ccattaaaaa
     2101 tcaagcgcat gggaattaac ggtgagggaa tcggctttta ccaaaaaaca ttagtctttg
     2161 taccaggagc tctcaaaggc gaagatatct attgtcagat tacttctatt agacgcaact
     2221 ttgttgaagc aaaattactg aaggtcaaca agaagtctaa atttcgaatt gtgccatctt
     2281 gtactattta taatgaatgc ggaggctgcc aaatcatgca cctgcattat gataagcagc
     2341 tggagttcaa gacggactta cttcatcaag cgctgaaaaa atttgctcct gcaggatatg
     2401 aaaattatga aattcgtcca actattggaa tgcaggaacc aaaatattac agagctaagt
     2461 tacaatttca gactcgaaaa tttaaaaatc aggtcaaggc gggcttatat gcacaaaact
     2521 ctcactattt agtagagttg aaagactgcc tggtacaaga taaggaaacc caagtgattg
     2581 ctaatcgctt agcagaatta cttacttatc accagattcc aatcacggat gagagaaaag
     2641 ttctaggtgt ccgtactatt atggtccgac gcgcgagaaa gaccggacag gttcagatta
     2701 ttattgttac aaaccgccag cttaatttaa ctcaattggt aaaagagttg gttaaagatt
     2761 tcccagaagt tgtgacagta gctgttaata caaatacagc taaaaccagt gagatatatg
     2821 gtgaaaagac agagattatc tgggggcaag agagtattca agaaggtgta ctcaattatg
     2881 aattttcact atcccctcga gctttttatc aactaaatcc tgagcaaaca gaagtcctct
     2941 atagcgaagc agtaaaagcg ctggatgttg ataaagaaga ccatttgatt gacgcttatt
     3001 gtggagttgg aacgattgga tttgcctttg caaagaaagt taaaacactc agaggtatgg
     3061 atattattcc agaagctatt gaagatgcca agcgaaatgc taaaagaatg ggatttgaca
     3121 atactcatta tgaagctgga acggcagaag agattattcc tcgttggtac aaggaaggct
     3181 accgagcaga tgctttgatt gttgacccac cacgtacagg tctggatgat aagttattag
     3241 atactattct tacttatgta ccagaaaaaa tggtttatat ttcttgtaat gtttcgacct
     3301 tggctcgtga tttggtacgc ttagtagaag tctatgatct tcattatatc cagtcggtcg
     3361 atatgttccc acatacagct cgaactgaag ctgttgtaaa attaataaaa aaagtttaaa
     3421 aaagtagttg acaaagtttg aaaaggctgt ataatagtaa gagttgaaaa taacaactca
     3481 ggtccgttgg tcaaggggtt aagacaccgc cttttcacgg cggtaacacg ggttcgaatc
     3541 ccgtacggac tatggtatgt tgcgtcagga
//
LOCUS       DBEJJV010000079         3096 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.079, whole genome shotgun sequence.
ACCESSION   DBEJJV010000079 DBEJJV010000000
VERSION     DBEJJV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 3096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3096
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.079"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..1242
                     /locus_tag="ACL3GT_002080"
     CDS             join(<1..332,332..1242)
                     /locus_tag="ACL3GT_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HGR0517666.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYPKKVKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
     gene            complement(1477..2085)
                     /locus_tag="ACL3GT_002081"
     CDS             complement(1477..2085)
                     /locus_tag="ACL3GT_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HGR0517667.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            2263..3021
                     /locus_tag="ACL3GT_002082"
     CDS             2263..3021
                     /locus_tag="ACL3GT_002082"
                     /inference="COORDINATES: protein motif:HMM:NF013539.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HGR0517668.1"
                     /translation="MADYILVRDSEIVYETSSEIVSKVKVGEGTLNRFCKKIGYSGFQ
                     ELKLKMTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIELAIKLIREAN
                     QILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDLIIAFSLSGS
                     TKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGGSLMAKASQL
                     FIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
BASE COUNT         1174 a          395 c          571 g          956 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccca acttagaaca agtgaagagt
      901 atgttagaac aagcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttgaaatcgg agatgtttta tggttatgag aagaacttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 ggacttagtt ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt
     1261 tggggtcagt acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc
     1321 ttgttttatt tttagaaaat ttactaaaga ctaaaaatat tatgaataat ttaaaaaata
     1381 gtcaggttat atagtttttt gaaattaaaa ttattttatc gttgaaatta gttaaaaatt
     1441 tttataaaat caagatgcaa ggctatgaga tgttctctag tttaattttt catacttcga
     1501 gaatataaag ttatataaaa atgcattagc atattttgtt attgagggaa gtataaaaat
     1561 cattaaagtt atccaaacta gtaattgatt ctgtaatata aagaagagta gaactgggat
     1621 aatttcaata attctaataa gaacggcaat aaaaaaatgt ttataggcta acatgattga
     1681 attgtgtaga gaatttttta aagtgttatt atatctaccg attaaaggaa ttagaaatgt
     1741 tgttgctatt aaatgaagta tgatatatat tactccaata tgtcgtaaga tagaaatgat
     1801 atatataggt aatggtatgt agggtaggaa gaacaaactg aataataaga ttaaaattgg
     1861 taaattagat attaatgctg ctcctaaatt tttccaataa tctttaaaaa aactgtttgc
     1921 gaagtctcta tagggatagg attcctcgtg tcgtacaatt tttattagag ttgctattag
     1981 ggcactttca cctgatccga tagcaataac tgttactact gacgctacat agagtagatt
     2041 taacattata agatttgaaa ctttatcaat aaattttatc tgcatcttta actcctgctg
     2101 tttttatact tataatatca catcatttga gtttcatcaa ctttgaatac attaagaaag
     2161 aatataacta tgaggaaagg aaaaaattat tatgaataaa tccaaaaaat ataaagaaag
     2221 aattcattat gaatacgata atcttactaa atcagagaaa aaattgctga ctatatttta
     2281 gttagagata gtgaaatagt ttatgaaacg tcttcagaaa ttgttagtaa agtaaaagtt
     2341 ggagagggaa ctcttaatcg attttgcaaa aagattggat actctggttt tcaggaacta
     2401 aaattaaaaa tgacgaaaga tatattagag ttagaatctc aaaaaatgag tagtgacaca
     2461 tttattgatg aaataaaaaa taattattta tctattgtgg aaagtacaag aaaattaatt
     2521 gatggtagac aaatagaatt agctataaaa ttaataagag aagcaaacca gattttaatg
     2581 attggtgtgg gttctagtgg aaatgcggct agagaatttg agagtagttt gttaagaatt
     2641 ggaataataa gtaagacggt aattgatacc cattttcaac tcatgcatac tgcgttattg
     2701 aaagataatg atttgataat agcgtttagt ttatctggtt ccacaaaaga agttgaggaa
     2761 actttattaa acgcaaaaag aaaaaatgtt aaaattattt caataacaaa ttattcgtcc
     2821 agaaatatag caaaattatc tgactgcgtt cttttgacat caaaaaaaga atcttattta
     2881 gagggtggta gtttaatggc taaggcttct caactattca taattgatgt aatatgcact
     2941 agactctctt taataaatta tgaagatact atatgtaaaa aagaagagat tgcttctttg
     3001 ctgtcaaata aagtggaata aatcaataat ttttaaattt taataaaaat tttttaaaat
     3061 aaattaaaaa acgatcctaa aagggtcgtt tttttg
//
LOCUS       DBEJJV010000080         2797 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.080, whole genome shotgun sequence.
ACCESSION   DBEJJV010000080 DBEJJV010000000
VERSION     DBEJJV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2797
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.080"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..821
                     /locus_tag="ACL3GT_002083"
     CDS             <1..821
                     /locus_tag="ACL3GT_002083"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0517669.1"
                     /translation="EKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPND
                     ESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYEEVPCEIPESWEWVRL
                     NDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLARFIDPETVHSYQKERLLRD
                     GDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRVLSGVINCHFIYNFLSSPI
                     VQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIVDKIEQFFAHIDALI"
     gene            878..1675
                     /gene="psrA"
                     /locus_tag="ACL3GT_002084"
     CDS             878..1675
                     /gene="psrA"
                     /locus_tag="ACL3GT_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HGR0517670.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1686..2294
                     /locus_tag="ACL3GT_002085"
     CDS             1686..2294
                     /locus_tag="ACL3GT_002085"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0517671.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETTSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(2242..>2797)
                     /locus_tag="ACL3GT_002086"
     CDS             complement(2242..>2797)
                     /locus_tag="ACL3GT_002086"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0517672.1"
                     /translation="NIPMNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIK
                     PLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGG
                     FIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLA
                     PFEEQELITQKVEKLFEKVNQLWK"
BASE COUNT         1010 a          409 c          466 g          912 t
ORIGIN      
        1 tagaaaaagt agatgaatat gctgaaagtt ataatagact agaacagcta gataaagaat
       61 ttccagataa actaaaaaaa tctattcttc aatatgctat gcaaggaaaa ttagttgaac
      121 aagacccaaa tgatgaatca gtcgaagttt tacttgaaaa aatacgagca gaaaaacaaa
      181 aactctttga agaaggcaag attaaaaaga aagatttgga catttctatt gtttcccaag
      241 gagatgataa ctcttattat gaggaagtac cttgtgaaat accagaaagt tgggaatggg
      301 tgaggttaaa cgatataacc tcctacattc aaagagggaa gtctccaaaa tattcaaata
      361 ttcctatata ccctgtgatt gctcagaaat gtaatcaatg gtctggcttt tctattgact
      421 tagcaagatt tattgatccc gaaacagttc atagttacca gaaagaaaga ttactaagag
      481 atggtgattt aatgtggaat tcaacaggtc taggtacgtt aggacgatta gctatttacc
      541 atgaaaataa aaatccttat ggctgggctg ttgcagatag ccatgttaca gttataagag
      601 tcttatcggg agttattaat tgccatttca tctataattt tctttcctct cctattgttc
      661 agtcagttat tgaagaaaaa gcgtcgggta gtacaaaaca aaaagaatta ttaacgaaaa
      721 ctataaaaga atatttaatc cccctcccac cccttcctga acaatccaga atcgttgata
      781 aaatcgaaca atttttcgcc catattgacg cactaattta gtataatagt tttacgtgcg
      841 gtggaatttc tatcaaacat aagataggag ttttacgttg aaagattttg aattacattt
      901 gaagaaagct ggtttagctg aaaatactgt gcgttcgtac ctttatggtg ttcgattttt
      961 cttggagaat tacgaactca aaatggaaga tttatttgaa tacaaaggat atttattaga
     1021 caattttaaa cctaaaactg tcaatttgcg actacaagga gtaaataaat atctggcttt
     1081 tattggtcat gatgatttga aattaaaatt tgtcaaagta cagcaaaaac catttttaga
     1141 agatgtcatt agccatgctg attacctttt tcttaaacgt agtttgaaaa aagatggtat
     1201 tttaaaatgg cattttgtcg tttggttttt aggtgcaact ggggctcgtg taagtgaact
     1261 tattaaacta aaagtagagc atgtagaaat cggttatttt gacatttact caaaaggtgg
     1321 taaaattcgt agactgtaca ttcctaaaaa attaagaaat agttgtctta gttggttaga
     1381 atcagaaaat cgccgaagtg gttatttatt tttgaataaa tttaacgaac caattacagc
     1441 aagaggagtt gctcaacagt taaaaaatta tgctgataaa tacaaaatga atcctaaagt
     1501 aatttaccct cattctttta ggcatttatt tgctaagaat tttttagcga agtataatga
     1561 tattgccttg cttgcagatt tgatgggaca cgaaagtata gaaactactc gaatttatct
     1621 aaggaaaaca gctactgaac aacaaaatat tgtagataaa attgttaatt ggtaaaaaat
     1681 aacaggtggt caaactgact acctgctatt tttgtgatta tggctcttat tatgggaaca
     1741 aagacgaaac aacctcttat cctatatatg aaatcccaga agcatggaga tatattaaat
     1801 ttgctagcct agttaacttc agaataggaa aaactcctcc acgcagtgaa gctacttttt
     1861 ggggaactga aataccttgg gtatctatat cagatatgcc tatatctggt tatgtaacta
     1921 atacgagaga atctatttct aaattagcat taaaatcaaa gaaaatagac atttcaccta
     1981 aaggaacttt attaatgagt tttaaattat ctattggaaa agttgccata ttggatattc
     2041 ctgccactca taatgaagcc attatatcga tattccccta tgctaataaa gaaaatatta
     2101 tcagagatta cttaatgata tttttgccac ttatctctac tttaggtgat tcaaaagatg
     2161 ctataaaagg gaaaacatta aatagtacca gtatctccga attattaatc cctatttcta
     2221 atcatgaaga gatgaaaaga atcatttcca aagttgattt actttttcaa aaagtttctc
     2281 aactttttga gtaataagtt cctgttcctc aaaaggagct aacggaatta atagctcgct
     2341 tagtgtagtt ttaggaatat tatataaagc ttgacctgat agtttagtta ttgctttcaa
     2401 ttgtttataa aataacggag aggacaagtt aaataataga aattttgaaa taatctctga
     2461 actttcgaat ggtgttaatt ggaaaataaa tccaccagcc acaacaccat catagtcttt
     2521 atcgattctt gcaaactttc caatatgttc taaagaggtt gatacaggtg ttattagctg
     2581 attatgtttt aaataaactt gttcagagga gatgaattgt gtatcaatgt agtaatcatt
     2641 atccaacaga gaaaattcta aaggcttaat attaccacca cgtataattc taacaccttt
     2701 attattaatg cttaaatcgc ccttcttgta agaaagacct gtattcattg aaaaaatatc
     2761 ttttattttt ataacaaccc aattcatagg tatattc
//
LOCUS       DBEJJV010000081         2563 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.081, whole genome shotgun sequence.
ACCESSION   DBEJJV010000081 DBEJJV010000000
VERSION     DBEJJV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2563
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.081"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            144..1340
                     /gene="tuf"
                     /locus_tag="ACL3GT_002087"
     CDS             144..1340
                     /gene="tuf"
                     /locus_tag="ACL3GT_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HGR0517673.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(1449..2563)
                     /locus_tag="ACL3GT_002088"
                     /pseudo
     CDS             complement(1449..2563)
                     /locus_tag="ACL3GT_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          787 a          501 c          542 g          733 t
ORIGIN      
        1 ttaaattttt accaagaata attcacaaaa acgttgtaaa acacttgcaa tttagctgaa
       61 atttgataaa atagtaagga aagttagact gtattgccta ctgtctatct ataaaatata
      121 ttttattgga ggcttttact caaatggcaa aagaaaaata cgatcgtagt aaaccacatg
      181 ttaacattgg tactatcgga cacgttgacc acggtaaaac taccctaact gcagctatca
      241 caactgtttt ggcacgtcgc ttgccttcat cagttaacca acctaaagac tatgcgtcta
      301 tcgatgctgc tccagaagaa cgcgaacgcg gtatcactat caacactgcg cacgttgagt
      361 acgaaactga aaaacgtcac tacgctcaca tcgacgctcc aggacacgcg gactacgtta
      421 aaaacatgat cactggtgct gctcaaatgg acggagctat ccttgtagta gcttcaactg
      481 acggaccaat gccacaaact cgtgagcaca tccttctttc acgtcaggtt ggtgttaaac
      541 accttatcgt cttcatgaac aaagttgact tggttgacga cgaagaattg cttgaattgg
      601 ttgaaatgga aatccgtgac ctattgtcag aatacgactt cccaggtgac gatcttccag
      661 ttatccaagg ttcagcactt aaagctcttg aaggtgactc taaatacgaa gacatcgtta
      721 tggaattgat gaacacagtt gatgagtata tcccagaacc agaacgtgac actgacaaac
      781 cattgcttct tccagtcgag gacgtattct caatcactgg acgtggtaca gttgcttcag
      841 gacgtatcga ccgtggtatc gttaaagtca acgacgaaat cgaaatcgtt ggtatcaaag
      901 aagaaactca aaaagcagtt gttactggtg ttgaaatgtt ccgtaaacaa cttgacgaag
      961 gtcttgctgg agataacgta ggtgtccttc ttcgtggtgt tcaacgtgat gaaatcgaac
     1021 gtggacaagt tatcgctaaa ccaggttcaa tcaacccaca cactaaattc aaaggtgaag
     1081 tctacatcct tactaaagaa gaaggtggac gtcacactcc attcttcaac aactaccgtc
     1141 cacaattcta cttccgtact actgacgtta caggttcaat cgaacttcca gcaggtactg
     1201 aaatggtaat gcctggtgat aacgtgacaa tcgacgttga gttgattcat ccaatcgccg
     1261 tagaacaagg tactacattc tctatccgtg agggtggacg tactgttggt tcaggtatgg
     1321 ttacagaaat cgaagcttaa ttcgatttag ttcccagaag aacaattatt taagtcagac
     1381 actaaaagaa tcttgcttgg caaggttctt ttttggttct ttgtcaactg tagtgggttg
     1441 aaaaaaaact aagctcgaga aaggacaaat ttcgtccttt ctttttgatg ttcagggcga
     1501 tgaaaatccg ttttttgaag ttttcaaagt tccgaaaacc aaaggcattg cgcttgataa
     1561 gtttgatgag attattggtc gcttccaatt tggcgtttga atagggtagt tgaagggcgt
     1621 tgacgatttt ctctttgtcc tttagaaagg ttttaaagac agtctgaaaa agaggatgaa
     1681 cctgcttaag attgtcctca atgagtccga aaaatttctc cggttcctta ttctgaaagt
     1741 gaaacagcaa gagttgatag agctgatagt ggtgtttcaa gtcttccgaa taactcaaaa
     1801 gcttgtttaa aatctcttta ttggttaagt gcatacgaaa agtaggacga taaaatcgct
     1861 tatcactcag tttacgacta tcctgttgta tgagcttcca gtagcgcttg atagccttgt
     1921 attcatgaga ctttcgatga aactgattca tgatttggac acgcacacga ctcatagtac
     1981 ggctaagatg ttgtacaatg tgaaagcgat caagaacgat tttagcattc gggagtgaaa
     2041 cagtctggga gactgtttca gcctgagcct agaaatttga aagcgaagct gtttagctaa
     2101 gtcatagtaa ggactaaaca tatccatagt aataattttg acgcgacatc ggacggctct
     2161 atcatattta agaaagtgat ctcggatgac agcttgtgtt ctaccctcaa gaacagtgat
     2221 gatattgaga ttgttaaaat cttgcgcaat gaagctcatc tccatctccc gattgaaaca
     2281 gtcactcccc ggactgtttc aacgtcccag gacataatct caggaagacg cgaaaaatca
     2341 tgctcaaagt gagaatcatt gagcttgcga atgacagttg aagttgagat ggaaagctga
     2401 tgggcaatat cagtcataga aatcttttca attaactttt gagcaatctt ttggttgatg
     2461 atacgaggga tttggtgatt cttcttgacg atagaagttt cagcgaccat catttttgaa
     2521 cagtgatagc acttgaatcg acgctttcta aggagaattc tag
//
LOCUS       DBEJJV010000082         2544 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.082, whole genome shotgun sequence.
ACCESSION   DBEJJV010000082 DBEJJV010000000
VERSION     DBEJJV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.082"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(410..1303)
                     /locus_tag="ACL3GT_002089"
     CDS             complement(410..1303)
                     /locus_tag="ACL3GT_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0517674.1"
                     /translation="MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENG
                     QALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFLKLKDELIHSQTYADKGRIERKE
                     AILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
                     VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQ
                     TEDSLIYIQTFEKIIAKTRHVFYRPHLFLLKAKYALFVDKNILEAESFYEKAISLAEL
                     LDDQVLVQRILAEKQIDFPTT"
     gene            complement(1324..1518)
                     /locus_tag="ACL3GT_002090"
     CDS             complement(1324..1518)
                     /locus_tag="ACL3GT_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517675.1"
                     /translation="MKKVLKYFLVFVFLFLMNIFIFKILATLGFQLIMSEKSYIVLPL
                     FSLIVLYMIDKRIRKKKKSL"
     gene            complement(1926..2051)
                     /locus_tag="ACL3GT_002091"
     CDS             complement(1926..2051)
                     /locus_tag="ACL3GT_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PncF family bacteriocin immunity protein"
                     /protein_id="HGR0517676.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKKFLKSSEKKTEKSVKK"
     gene            complement(2054..2284)
                     /gene="blpU"
                     /locus_tag="ACL3GT_002092"
     CDS             complement(2054..2284)
                     /gene="blpU"
                     /locus_tag="ACL3GT_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HGR0517677.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
BASE COUNT          843 a          527 c          273 g          901 t
ORIGIN      
        1 actactacat tttcctagat tatcaaatta cttttatatc actaagactc aataaaagat
       61 aatgtctatt taacttttat acgattacta cctccttttt agtttacact tcctacatca
      121 taaataaaca tactcaaccc tcacaatctc caaataactc ttctatatca ttgaaaattg
      181 agtttcatcc tctatactaa tgtaggaaac ctattaaaac attcctttaa tccaatataa
      241 gaataccttg ttccattaat ctctacccga tattatagat agaaccagac tcctatactt
      301 aaaaggacaa ataacgttcc aaccataata aacctccttt ctttttgaga acgttttctt
      361 tataggttta gtatagcaaa aacatgaaaa aaacaacctg acttagaagt caggttgttg
      421 ggaaatctat ctgtttttct gctaaaattc tctgaactaa tacctgatcg tctagcaatt
      481 ctgctagaga aatcgccttt tcatagaaac tttctgcctc taaaatattc ttgtctacaa
      541 ataaagcata ttttgccttt agcaaaaata gatgaggtcg gtaaaaaaca tgtcttgttt
      601 tagcaataat tttctcaaat gtttgaatat atatcagact atcttctgtc tgaatttgga
      661 taaataggct cagaagaact ttttccattt gaactaggct agccttatct tcatattctg
      721 aacatagcaa tactttttga gctaactcct caaaatgttc tttatcttct aatcccatag
      781 cacaacaaaa gaaatacaat tcaataatca acaaatcatt tacagaaaaa tatttctttt
      841 ttaataactg ctggaaatat tcttccacta accctaaacc gtaggtcaca tctgaactac
      901 cataaatatc aaaacgagct tgtgtcacat ccacaattaa ctgctcttcc tcaggcaaat
      961 tctcataata gttttcatat atttcctcaa gtatagcttc ttttcgttcg attcttccct
     1021 tatcagcgta ggtttgagaa tgaatcagct catctttgag ttttaggaat ccttttggaa
     1081 tctctataac cttaacatcc acaatattct gtaatgatac tccaagttta tccgcaatca
     1141 ataataattt aggaagtgtt gctaaagctt gcccattttc aatacgtgct agctgacgaa
     1201 tcgtcaactc tgattcatca ccacaaatat ctatctgagt ttttccacaa gatcgcctaa
     1261 tagttttgat tttataacca atttcacgtt tcaactcatc catagtaata ctccttaagt
     1321 tgattacaaa gatttctttt tcttcctaat tcttttgtca atcatatata aaacgataag
     1381 cgaaaacagc ggtagaacaa tataactctt ttcactcatt atcagctgaa atcccagggt
     1441 tgctagtatc ttaaagatga aaatattcat caaaaataga aaaacaaata ctaaaaaata
     1501 ttttaaaacc ttcttcattt cttttcttca actttcctaa tttctacacc tattttatcg
     1561 aaaatatata taaaactcca aataaacact tcgactgcac tttttttggc aaaaaataga
     1621 cagaacaaac atcctatcta ctaaaaatat gatatgaaag gaaattgatt ttttactgtc
     1681 accctaggca agcttgaaac aaataaatca ttgatagtaa cacttacgac atcctattta
     1741 ttacttcaat ttctaatgtc tctgctattt ctaagctacc tctggtatga tctattccta
     1801 gtcagaatag ataacaccgt tctaaattac gattcatagt tactcctttt ttgactcgtt
     1861 actataagac tcctctttac atgcgcaaaa taattttgat tcagattcat catttatagt
     1921 tttgattatt ttttaacaga tttttctgtt ttcttctccg aagactttaa aaattttttt
     1981 ctaattaaat catccatata aggaccaaat ataccaacta ctaaaccaat aataaaactt
     2041 ttaaaatcca taattaccac caacatgtcg ctgcataggc cacacctcca agtatagctc
     2101 ctcccgcagc accagttgct gcaccttgcc atgttcttgt tttaattcct agctgaagac
     2161 ctcgtactgc tcctcctcca acacctgctt tggcaaaatc tccccaattg catccgccac
     2221 cttcaacgca agcaagcatc tcagtatcca taatttcaaa ttgtgacatc ttttttgtat
     2281 tcataacgaa tacctctttt ttatttttaa tatttgtctt gttacaaact tgacaagttt
     2341 agtataacag tatctattaa tttttttcat ccaaatcttg aattggcatc gaaacgtctt
     2401 gaattagctt ttttgtttca aaatcatctc tatttttaaa aaagatgttt tctaatcact
     2461 tttttactat tagacttcct gcaaaactag aatcctagtt catgattgat aatgccagca
     2521 atcaaattca ttcgtaatcc gaag
//
LOCUS       DBEJJV010000083         2373 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.083, whole genome shotgun sequence.
ACCESSION   DBEJJV010000083 DBEJJV010000000
VERSION     DBEJJV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.083"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..582
                     /locus_tag="ACL3GT_002093"
     CDS             <1..582
                     /locus_tag="ACL3GT_002093"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HGR0517678.1"
                     /translation="NKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKNVTK
                     NGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRINSGM
                     VILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQNEFA
                     DFVVQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            642..878
                     /locus_tag="ACL3GT_002094"
     CDS             642..878
                     /locus_tag="ACL3GT_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HGR0517679.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            875..1288
                     /locus_tag="ACL3GT_002095"
     CDS             875..1288
                     /locus_tag="ACL3GT_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HGR0517680.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            1406..2371
                     /gene="xerA"
                     /locus_tag="ACL3GT_002096"
     CDS             1406..2371
                     /gene="xerA"
                     /locus_tag="ACL3GT_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008907 - integrase activity [Evidence
                     IEA];
                     GO_function: GO:0009037 - tyrosine-based site-specific
                     recombinase activity [Evidence IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase/integron
                     integrase"
                     /protein_id="HGR0517681.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
BASE COUNT          877 a          357 c          445 g          694 t
ORIGIN      
        1 aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga taggggcaaa
       61 aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt aaatacaaag
      121 aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa aacaaaggat
      181 aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac aagaggtact
      241 gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg tataaattca
      301 ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat tatccatgtt
      361 ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca gttaccaatt
      421 acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa tgagttcgca
      481 gactttgtag tccaggtcga caaatcacaa ttggcaatcc aaaaatctct ggaagaactt
      541 gaaactttga agaaatctct gatgcaggag tattttggct gatattctgc cattgtaatt
      601 acggtaatga tttgttataa tacttcaaag gaggaaatca gatggtagta aaaacaagaa
      661 aacaaggaaa ttcaatcacc attacgattc caagtgaatt taatattcca agtggtgtta
      721 aatacgaagc gaaattgtta ccaagtggtg agattatctt tactcctgaa gaattggggc
      781 agcaggtttc ttatgtatct gatgatgcct ttgacttaaa tttagataaa atatttgacg
      841 aatacgacga tgttttcaaa gctttggtgg aaaaatgaca atctatctga cagaaaagca
      901 aattgaaaaa ataaatgctt tagcaattca acggtattct ccaaatgaga aaattcaaac
      961 agttagttct tctgccttaa atatgattgt gaacttacca gaacaatttg tctttgggaa
     1021 gtctctttat ccaacaattt ttgataaagc aacgatacta tttgtccaat tgataaagaa
     1081 gcatgttttt gctaatgcta ataaaagaac tgctttcttc gttttggtca aatttttaca
     1141 attaaacggc tatcgttttt ctgtaacggt agaagaagca gtaaaaatgt gtgtaaccat
     1201 cgcagtagaa gctttaactg atgaaaaaat gacaagctac tccaaatggg tttctgaaca
     1261 ttctgttaga gaaaaggtca aaaagtaacc tagtatgctg gatttgaatg agcacaagaa
     1321 aataaatgaa cagacaatat tagaattctg taatgcagaa actgatattg tctcttttta
     1381 ttgatgaata agaaagtgag aaattatgga atcaaaagtt acaattatca tgcaagaaat
     1441 gttacctctt ttaaataatg aacaattact agcgttgaga gagagtttag aacatcatct
     1501 agtagacgga aaaaagcagc agaagtattc gaataataac ctgttgcaac tatttattac
     1561 cgccaagcag gtagagggct gtagctcaaa aacaattcgt tattaccaga ggacgattga
     1621 aaacttgttt aatgctatta aagagtctgt gacacaactc acaacagatg atttaaggag
     1681 ttatttagca aattaccagt ctgaaaagga ttgtagtaag gcaaatttag acaatattag
     1741 gcgtatattg tcttcttttt ttgcttggct tgagcaagag gaatatatca ttaaaaatcc
     1801 cattcgacgg ataaagaaaa ttaagactga gcaaaatgtg aaggaaactt atactgatga
     1861 acatttggaa attatgcgtg ataactgtga aaatttgaga gatttggcaa taatagacct
     1921 actagcatcg acaggtatgc gtgtagggga gcttgtacag ttgaatcgtt cagatattga
     1981 ttttgaaaac agagagtgtg ttgtctttgg taaaggaaag aaggagagac cagtatattt
     2041 tgacgctcgg acgaaaattc atttaagaaa ttatcttaac gacagaaaag atagtcaccc
     2101 tgctcttttt gtaacgctag ttggaaaagc ccagagactt ggaattgctg gtgtagagat
     2161 tcgcttaaga aagttaggag acaaactcgg catacaaaag gttcacccac ataagttcag
     2221 aagaacttta gcgactaagg caattgataa aggtatgcct atcgaacaag tccaaaaact
     2281 gctaggtcat agcaagattg acacaaccct ggcctatgcc atggtcaatc aaaataatgt
     2341 caagcattca caccaaaaat tcatctctta aaa
//
LOCUS       DBEJJV010000084         2324 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.084, whole genome shotgun sequence.
ACCESSION   DBEJJV010000084 DBEJJV010000000
VERSION     DBEJJV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.084"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..590
                     /locus_tag="ACL3GT_002097"
     CDS             <1..590
                     /locus_tag="ACL3GT_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0517682.1"
                     /translation="KNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFC
                     GDDIKKTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKD
                     FPNNILDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERK
                     ILDREDLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            939..1367
                     /locus_tag="ACL3GT_002098"
     CDS             939..1367
                     /locus_tag="ACL3GT_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517683.1"
                     /translation="MSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLDNINSVPSTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            1379..2128
                     /locus_tag="ACL3GT_002099"
     CDS             1379..2128
                     /locus_tag="ACL3GT_002099"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019213 - deacetylase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HGR0517684.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            2141..>2324
                     /locus_tag="ACL3GT_002100"
     CDS             2141..>2324
                     /locus_tag="ACL3GT_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HGR0517685.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNI"
BASE COUNT          836 a          244 c          435 g          809 t
ORIGIN      
        1 taaaaaactt aaatttttgt tttcaacgta atgaaaagta tttaatttta ggtgaaagtg
       61 gaagcgggaa atctacatta ttaaaattat tgaatggctt tttgagagat tatagtggag
      121 aattgcgatt ctgcggggat gatataaaaa aaacctccta tttaaatatg gtttcgaatg
      181 ttctatatgt agatcaaaaa gcttatttgt ttgaaggtac gattagagat aatattttat
      241 tggaagaaaa ttatactgat gaagaaatac tacagtcttt agagcaagtt ggtttgagtg
      301 taaaagattt tcctaataac attttagatt attatgttgg tgatgatggg agattactgt
      361 caggagggca gaaacaaaaa attactttag ctagagggct aattagaaat aagaaaatag
      421 tattaattga cgagggaact tctgctatcg ataggagaac ttcgttagcg attgaacgta
      481 agatattaga tagagaggat ttgactgtca ttattgttac ccatgctccg catccggaac
      541 ttaaacaata ttttactaag atatatcaat ttccaaagga ttttatttaa gaatataggg
      601 gagggaaaca tgagattcta ttgtgaagct tatgaggtaa ttactgaaga gaaaaaagta
      661 tactttaatg atattgagtt agaagttaag tattcctctg tcgaagaatt gtttataata
      721 tgtgagaaat tattagataa gaaaaaagta tcattttttt atgtagatga gaaaccctta
      781 aggtatctgt tatttgacta tatatttcta ctagttctag ctaaaaaaat atcccaatct
      841 tatgaactgc accccaaaag ttagatttat tctgtctaac ttttggggtg cagttcattt
      901 tgcatagttt tggcattcat cctagatatc catataaaat gtctgagatt gttgaaatgt
      961 ctaaaaaaat atcagatcta aacgataaaa aagaatttca caaaaagaac tgtgagttga
     1021 ggtttcaaga tagtgttctt gataacataa atagtgtccc gagtacaact catttattta
     1081 gttgtttaaa tattcaaaca ttagtaaaaa ttattttata tatttttcga tacaacagtt
     1141 gtatgaaaat atttaatttt agagataaag agcttatctt ttttaataag attgtaaatg
     1201 ggctgataca aaatattgag gagaatttag aggatgatat tgaaaggata ttgaaatatt
     1261 tatatatatg tttatttaac gaaatattca ttattaagaa taaggtgaat ttttttgatg
     1321 atgtggaatt taatcagaca cttagtgagt ttttagataa attgtagagg gaatggttat
     1381 gagtaacaat actaagtata tctttttatc tccacattta gatgacgcaa ttttttcctg
     1441 tggtgattat atttcaaaat taacttcaga aggagaaatt gtacttgtta ttactatatt
     1501 ttctggttac cctttgagcc aacagctaca gccctctgct aagcaatttc ataagttgtg
     1561 taaccttggg aaatatccga ttgaagaaag gaagaaagaa gacaggttag cttgtgaacg
     1621 tctacagtgt gattttagac acttatcgta ctatgaatgt ctctatagga aagatagaaa
     1681 tggcaatttt ctataccgtc atatctatag tgaattaaaa aatgaggaca cattaaagaa
     1741 tgatatcata aaagagctgt taatgcattt agacgacaaa tgtgtcgtat attgtccgct
     1801 ttcacttggt gaccatgttg atcatgtttt tgtgaatagt attggaaggg cgcttgaatt
     1861 tatgcgttat aaagtaatat attatgagga cttcccatat gtaagtgata gtagtatggt
     1921 tagttatatg ggaaaaacta aagaattaaa aatgtatcaa gaggaacttg atgaaaaaca
     1981 ttatattgat agaatatcat caatattgtg ctataaatct cagattttga taatctggaa
     2041 atcagttgaa aaacttttaa acaatattaa agagttgtat ttaaggaatg gggcagctta
     2101 ttctattaga ttttggatta agaaataagg aagtagtttt atgaatatag cagtaattgg
     2161 tttggggcat gttgggctgg cctacgcgtt actatttgca tctaaatata aagttgttgc
     2221 atatgatata gattctgtaa aaataaataa tttaaaaaag ggcattcttc catctaaaaa
     2281 tgaagagctt atgaagtttt tttgcgagaa taacttaaat atta
//
LOCUS       DBEJJV010000085         2247 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.085, whole genome shotgun sequence.
ACCESSION   DBEJJV010000085 DBEJJV010000000
VERSION     DBEJJV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 2247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2247
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.085"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..275)
                     /locus_tag="ACL3GT_002101"
     CDS             complement(<1..275)
                     /locus_tag="ACL3GT_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HGR0517686.1"
                     /translation="MRNYEASKQLTDTRFKRLVGVQRTTFKEMLAVLKTDYQLKHAKG
                     GRKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLIRRSQWVEV"
     gene            complement(262..444)
                     /locus_tag="ACL3GT_002102"
     CDS             complement(262..444)
                     /locus_tag="ACL3GT_002102"
                     /inference="COORDINATES: protein motif:HMM:NF016232.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0517687.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            779..>2247
                     /gene="pcpA"
                     /locus_tag="ACL3GT_002103"
     CDS             779..>2247
                     /gene="pcpA"
                     /locus_tag="ACL3GT_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HGR0517688.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKG"
BASE COUNT          799 a          324 c          370 g          754 t
ORIGIN      
        1 acttcaaccc attggctccg acggattaag ttgctttcgt gaataccaaa atcagccgca
       61 atttcttcat aagtgcggta ttctcgcaca tattgaagag tggccataag aaggtcttct
      121 aggcttaatt taggttttcg tccacctttt gcgtgtttaa gttgataatc tgtttttaac
      181 acagctaaca tctctttaaa agtggtacgc tgaacaccaa caagacgctt aaatcgtgta
      241 tcagttaatt gtttacttgc ttcataattt cgcagggagt ctattgactc tttggtaggt
      301 gtcaatgttt ttttcatcta taccgagaat tattttcccg ccatttgtat ttgcaaatgc
      361 tgagtaggtt tcccagaaag actctggaag attgttttta gcttttttgt attctaaatc
      421 aaccccttca aattttaagt ccatattttt cctttacatc tgttttttgt ggttctggta
      481 tttgttcaag ttgagtgata atatagcgaa ttgaatttcg agagttttta ctcagttaat
      541 ttctttttta acccgcttta atttcttttt taacacgtgt taaaaaagaa attaaagcgg
      601 gttaattttt cttgacttaa aatttaaaaa tgatatactg tgtttatgga gagatgacaa
      661 tttataaaat gtactactct attctactag ataatgattg aataaaactt tttataacaa
      721 cggctagcaa agttataatt ttatatctat tagaaaataa atatgtaagg aaatttaaat
      781 gaaaaaaact acaatattat cattaactac agctgcagtt attttagcag catatgtccc
      841 taatgaacca atcctagcag atactcctag ttcggaagta atcaaagaga ctaaagttgg
      901 aagtattatt caacaaaata atatcaaata taaggttcta actgtagaag gtaacatagg
      961 cactgttcaa gtgggtaatg gagttactcc tgtagagttt gaagctggtc aagatggaaa
     1021 accattcacg attcctacaa aaatcacagt aggtgataaa gtatttaccg ttactgaagt
     1081 agctagtcaa gcttttagtt attatccaga tgaaacaggt agaattgtct actatcctag
     1141 ctctattact atcccatcaa gcataaaaaa aatacaaaaa aaaggcttcc atggaagtaa
     1201 agctaaaact attatttttg acaaaggtag tcagctggag aaaattgaag atagagcttt
     1261 tgatttttct gaattagaag agattgaatt gcctgcatct ctagaatata ttggaacaag
     1321 tgcattttct tttagtcaaa aattgaaaaa gctaaccttt tcctcaagtt caaaattaga
     1381 attaatatca catgaggctt ttgctaattt atcaaattta gagaaactaa cattaccaaa
     1441 atcggttaaa acattaggaa gtaatctatt tagactcact actagcttaa aacatgttga
     1501 tgttgaagaa ggaaatgaat cgtttgcctc agttgatggt gttttgtttt caaaagataa
     1561 aacccaatta atttattatc caagtcaaaa aaatgacgaa agttataaaa cgcctaagga
     1621 gacaaaagaa cttgcatcat attcgtttaa taaaaattct tacttgaaaa aactcgaatt
     1681 gaatgaaggt ttagaaaaaa ttggtacttt tgcatttgca gatgcgatta aacttgaaga
     1741 aattagctta ccaaatagtt tagaaactat tgaacgttta gccttttacg gtaatttaga
     1801 attaaaagaa cttatattac cagataatgt taaaaatttt ggtaaacacg ttatgaacgg
     1861 tttaccaaaa ttaaaaagtt taacaattgg taataatatc aactcattgc cgtccttctt
     1921 cctaagtggc gtcttagatt cattaaagga aattcatatt aagaataaaa gtacagagtt
     1981 ttctgtgaaa aaagatacat ttgcaattcc tgaaactgtt aagttctatg taacatcaga
     2041 acatataaaa gatgttctta aatcaaattt atctactagt aatgatatca ttgttgaaaa
     2101 agtagataat ataaaacaag aaactgatgt agctaaacct aaaaagaatt ctaatcaggg
     2161 agtagttggt tgggttaaag acaaaggttt atggtattac ttaaacgaat caggttcaat
     2221 ggctactggt tgggttaaag acaaagg
//
LOCUS       DBEJJV010000086         1914 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.086, whole genome shotgun sequence.
ACCESSION   DBEJJV010000086 DBEJJV010000000
VERSION     DBEJJV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.086"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            104..400
                     /locus_tag="ACL3GT_002104"
     CDS             104..400
                     /locus_tag="ACL3GT_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HGR0517689.1"
                     /translation="MKSKRMEFHNKFLIVSAMLAVISWLSLGVVSFPMLAGTLGISTK
                     AAATVVNLISAYSTVTAVISIVGAITGVGSIGSGIAATVLYILKKKGAAKAALW"
     gene            407..1543
                     /locus_tag="ACL3GT_002105"
     CDS             407..1543
                     /locus_tag="ACL3GT_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517690.1"
                     /translation="MKILSKKECESILGYLNFIGITLLFFVIISLSIYFKSYLPFQGK
                     LFLLFLVVDYATLNRYNMKLPIQSKKINTFYIRKNYIFLYLLAIVKKYYSFQILQSFI
                     YLFILYFLDIIGYFYLSITLCLIAIQIISLILPSLFSIISKLFLFLSIGLLSIEQGQV
                     VIYVILLNYFILVMGILDNHASNFYFKSSRMSQKRFRSSLFILLRFCWLNKGLTFSFI
                     LISILLSYLFWYMMTMLSIDDTKIPILFLYTSIYITLMEAIIGNHKSSIGVDLALLQL
                     SALNHSKMNFFFKNAQLMMLTHLISFLQFSLLLCLIPVTSYSNDIKSILLNLLLIPFN
                     YFIAYVYYKKALFLIKGTVSLLRWSFLVLYCFLIIFVILVGGIR"
     gene            1540..>1914
                     /locus_tag="ACL3GT_002106"
     CDS             1540..>1914
                     /locus_tag="ACL3GT_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HGR0517691.1"
                     /translation="MRKSGFLIYYVLFCIVCFLLGLLLSFILKNETFATIPPKLELQF
                     TLTVLQANSTNFLLYLFCFPISPLLQLFDLLSLGIQLGISGQMIGIVATIKGILPHAL
                     IEIPNFIWYQGMSQYLLYRLLKD"
BASE COUNT          597 a          236 c          293 g          788 t
ORIGIN      
        1 gtagtataaa atatagacga acatttgaag agagttagga atacaacatg tgcgaattaa
       61 ctctcaataa aacatacata atatacaaaa ggagtacact aaaatgaaat ctaaaagaat
      121 ggaatttcat aataaatttc ttattgtttc agcaatgtta gcagtcatta gttggttaag
      181 cttaggtgtt gtttcttttc ctatgttggc tgggacatta ggaatttcga caaaagctgc
      241 tgctactgta gtcaatttga ttagtgctta tagtacagtt acagcagtaa tttcaattgt
      301 aggtgcaatc acaggagtag gttctattgg ttcgggtatt gcagcaacag ttctttatat
      361 attgaaaaag aaaggtgctg ctaaagcagc tctatggtag aactagatga aaatactttc
      421 taaaaaagaa tgtgaaagta ttttaggtta tcttaatttt attgggataa cccttttgtt
      481 ttttgttatc ataagtttgt caatctattt taaaagctat cttccttttc aagggaaatt
      541 atttttactt tttttggtag tagattacgc tactttgaat cgttataata tgaaactgcc
      601 tatccaaagt aaaaaaataa atactttcta tataaggaaa aactatattt ttctctatct
      661 tcttgccatt gtcaagaaat attattcttt ccaaatttta caatcattca tttatttatt
      721 tattttgtat tttctagata ttattggata tttttattta tccattactc tttgtttgat
      781 agctattcaa attatttctt taattctacc tagtttgttt tcaattataa gtaaattgtt
      841 cttattttta tctataggac tattgtctat agaacaagga caagttgtaa tttatgtcat
      901 actactcaat tattttattt tagtcatggg gatattagat aatcatgcga gtaatttcta
      961 ttttaaaagc agtcgaatga gtcaaaaaag atttcgtagc agtctattta tattgcttcg
     1021 tttttgttgg ttaaataaag ggttaacttt ttcttttatt ttgattagta ttcttctttc
     1081 ctatctattt tggtatatga tgacgatgtt atcaattgat gacacaaaaa taccaatatt
     1141 atttctttat acctcaatat atattacatt aatggaggca ataataggga atcataaatc
     1201 ctcaattggg gtagatctag ctttacttca attatctgct cttaatcatt ctaaaatgaa
     1261 tttctttttt aagaatgcac aactaatgat gttgacgcat ttaatctctt tcttacaatt
     1321 ttcattgttg ttatgtttga ttccggtgac aagttatagt aatgatataa aaagtatttt
     1381 gttgaatttg ttattgattc cattcaatta ttttatagcc tatgtctatt ataagaaagc
     1441 tctattttta attaaaggta cagttagttt attgagatgg agttttctgg ttttatattg
     1501 ttttctgata atatttgtaa ttttagtagg gggcattaga tgagaaaaag tggttttctg
     1561 atttactatg tgttattttg tatagtctgt tttttactag gtttactttt aagctttata
     1621 ttaaaaaatg agacttttgc tactatacct ccgaaactgg aattacaatt tacattgaca
     1681 gttttacagg caaattctac aaattttttg ctatatctat tctgttttcc gatttcgccc
     1741 ttattgcaac tttttgattt gctatcttta ggaatacaat tgggtatatc tggtcagatg
     1801 attggaatag tagctacaat aaaaggaata ttacctcatg ctcttattga aataccgaat
     1861 tttatttggt atcaaggtat gagtcagtat cttttatacc gattattgaa ggat
//
LOCUS       DBEJJV010000087         1736 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.087, whole genome shotgun sequence.
ACCESSION   DBEJJV010000087 DBEJJV010000000
VERSION     DBEJJV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1736
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.087"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..696)
                     /locus_tag="ACL3GT_002107"
     CDS             complement(<1..696)
                     /locus_tag="ACL3GT_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HGR0517692.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILS"
     gene            complement(1141..1539)
                     /locus_tag="ACL3GT_002108"
     CDS             complement(1141..1539)
                     /locus_tag="ACL3GT_002108"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HGR0517693.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          489 a          347 c          295 g          605 t
ORIGIN      
        1 ggaaagaatc ttgtgttgtt ttaagatgag ttttagagcc tgattgacca cctcagcact
       61 tttatttgga atcaatcgga tgatctgatg tctactcttt cgatccgtca agacaagcaa
      121 gcagtagttt ttcgctctcg taagtagaac cgtatcaatc tcataatgcc cattctccaa
      181 gcgaagattg atagcttcag accgctgttc gatggattga ccagcaggtt taaagttggt
      241 gctagcctgt ttcttaagcg cttttccttt tctagggtaa agcagatcct gtttgcttaa
      301 ccccaatttt ccatgatgaa tccaatagta aatggttgaa attcccacgt taaccccttt
      361 agccatcacc atcatttcag gcgaaaattt ttggttatga tagtggagaa tcttttcctt
      421 tagttccttg gtcaagcttg atttcttgac cgagcgcttg cgattatttt cataagactg
      481 ttgagcatag tcggcagaat aaacctcttt gaagcgccct tttccaagac attgtcggac
      541 tgtcccacgc ttgatttcag tgtggatagt ttgaggaact tttccaagca gagaggcaat
      601 ttctctattt gatttccctt cttttttcca tctttcgatt aagcgacggc tatcgattgt
      661 caaatgtttg gcttttgtag tataattgtc ttgcatctct gtgcctttct tgtgtttgtg
      721 gttgaacaac aagtataaca cagaggtgtt ttcttatgcc tacaagagct ttcattattt
      781 ccattttctt ttggatttca ctctattctg aaaaacttgt gtatatttac tgaagctagc
      841 aagtcttacc tgtaaattta atgaaagcaa cacaaaatcc gagaggggaa tctcggatta
      901 atagatagag agtttttagt ttaaataaat tgtttaaaat atcaacaaca tcacttcttt
      961 tcttaacctg ataagtcttg attcctaatt ttggggctac gattatattg tcctcaatat
     1021 cgtctagaaa gacacaattt ctaggttata actggtattt atcgatagtt actcatatac
     1081 atcagtccac ctccatactt atgtgcgagc ctctctttgt attatacctc catactcacc
     1141 ttacagattc ttttggtaat aatatctttg cctaatgtag agatagtctt gcaaagaaaa
     1201 aacttccttg tagccatgtt tctgataaaa gtccggtgcc tggaactggt aagtattgac
     1261 aaaggcaaaa caacaatttc gattcttagc ttcactttct gcctgttgca atagttttga
     1321 accgattcct tgccctcgca gttcctcttt tacaaacaaa tactcgattt ctagccaatt
     1381 tccaaaagtc tctgctatca aacctgccag gagattgccc ttttcatctt cgacataaag
     1441 attaagtggc tcactttcag cctcttctct ttttgaacgg ttataaacac gaatcagatt
     1501 ccctatttct tgcgatttat gtgattcctt attttccaat ctaaagtata gtgaaatgaa
     1561 ataaaacatg cgcaaatcga ttaaggaatt taatctaatt tctaacaatg tcttagaaat
     1621 caaagtgtac tattttaact tcaatgcact atacatctaa tactcaataa aaatcaaaga
     1681 gcaaactagg aaactagccg caggttgctc aaaacactgt tttgaggttg tagata
//
LOCUS       DBEJJV010000088         1662 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.088, whole genome shotgun sequence.
ACCESSION   DBEJJV010000088 DBEJJV010000000
VERSION     DBEJJV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.088"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            146..1492
                     /locus_tag="ACL3GT_002109"
     CDS             146..1492
                     /locus_tag="ACL3GT_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HGR0517694.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT          491 a          359 c          325 g          487 t
ORIGIN      
        1 tctaaaaacc atccagaatc cttgccttag cttagatcct ggatggtttc ttttttcacc
       61 caatgggtgt tttttactag acaaaaaaga gtttcccctt tatggtataa gtgtagaaaa
      121 aaacacaaaa agaaaggaaa ctcacatgaa cagtttacca aatcatcact tccaaaacaa
      181 gtctttttac caactatctt tcgatggagg tcatttaacc cagtatggtg gtcttatctt
      241 ttttcaggaa cttttttccc agctgaaact aaaagagcgg atttctaagt atttagtaac
      301 gaatgaccaa cgccgctact gtcgttattc ggattcagat atccttgtcc agttcctctt
      361 tcaactgtta acaggttatg gaacggacta tgcttgtaaa gaattgtcag ctgatgccta
      421 ctttccaaaa ttattggaag gagggcagct tgcttcacag ccaaccttat cccgttttct
      481 ttccagaact gacgaggaaa cagtccatag tttgcgatgc ctcaaccttg aattggtcga
      541 attcttttta cagtttcacc agctaaacca actcattgta gatatcgatt ctacccattt
      601 cacaacttat ggcaagcaag aaggtgttgc ttataacgcc cactatcgtg ctcatggcta
      661 tcatcctctt tatgctttcg aggggaagac aggttattgt ttcaatgccc agcttcgtcc
      721 tggtaatcgt tattgttctg aagaggcaga cagctttatc acacctgttt tagaacggtt
      781 taatcaactt ctctttcgaa tggatagtgg ctttgcgacc ccaaaattat acgatttaat
      841 tgaaaaaaca gggcaatact acctcataaa actcaagaaa aatactgttc tgagccgtct
      901 tggagacctt tccctccctt gcccacagga tgaggactta accatcttgc cccactccgc
      961 ctactcagaa actctctatc aagcaggatc ttggtcgcac aagcgtcgtg tctgccagtt
     1021 ctctgaacga aaagaaggaa acttgttcta cgatgttatt tctctcgtta caaatatgac
     1081 gagtggaaca agccaagacc agtttcagct ttatcgtgga cgtggtcaag ccgagaattt
     1141 catcaaggag atgaaggagg gattttttgg cgataaaacg gatagttcaa ccttaatcaa
     1201 aaacgaagtt cgtatgatga tgagctgtat cgcctacaat ctctatcttt ttctcaaaca
     1261 tctagctgga ggtgacttcc aaactttaac aatcaaacgc ttccgccatc tttttcttca
     1321 cgtggtagga aaatgtgttc gaacaggacg caagcagctc ctcaaattgt ctagtctcta
     1381 tgcctattcc gaattgtttt cagcacttta ttctaggatt agaaaagtca acctgaatct
     1441 tcctgttcct tatgaaccac ctagaagaaa agcgtcgtta atgatgcatt aaagaacagt
     1501 cgagatgaaa aaatcgtgtg acgaaccaag ggaggagtct gcccttttga ggaaatctag
     1561 cgaggaaaaa cgatactgga acagcagaaa gtaaaactga cctcatgagg aggaagaaag
     1621 tggctcatga ggtcaggggt tttgtaagtt acatctagtt ga
//
LOCUS       DBEJJV010000089         1609 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.089, whole genome shotgun sequence.
ACCESSION   DBEJJV010000089 DBEJJV010000000
VERSION     DBEJJV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1609
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.089"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            35..491
                     /locus_tag="ACL3GT_002110"
                     /pseudo
     CDS             35..491
                     /locus_tag="ACL3GT_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            656..955
                     /locus_tag="ACL3GT_002111"
     CDS             656..955
                     /locus_tag="ACL3GT_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HGR0517695.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKASVDEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="ACL3GT_002112"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="ACL3GT_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HGR0517696.1"
                     /translation="MMIQLSDLGQVHLVCGKTDMIQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWILYKRFENGKLTWPSTEKDVKALAPEQVDWLMKGFS
                     ITPQI"
BASE COUNT          552 a          321 c          282 g          454 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattgacta atactcttcg aaaataaaat tcaaaccaca tcagcgtcgc cttaccatac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttt attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag gcctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataata aaacgcatag
     1021 tagcaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcggag
     1201 gaaaagtatt gtactatgat gattcaacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgataca aggaatcgat tcactggctt atctcgttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggatactat ataaacgctt tgagaacgga
     1441 aaactgactt ggcccagtac agaaaaggat gtcaaagctc tcgcacctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacccctact tctaaaacat tgttagaaat cgatttgact gtcctgatc
//
LOCUS       DBEJJV010000090         1466 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.090, whole genome shotgun sequence.
ACCESSION   DBEJJV010000090 DBEJJV010000000
VERSION     DBEJJV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.090"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            108..1286
                     /locus_tag="ACL3GT_002113"
     CDS             108..1286
                     /locus_tag="ACL3GT_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HGR0517697.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLISQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT          545 a          268 c          215 g          438 t
ORIGIN      
        1 aaagagacca gtaagcaatg aaaagcttaa aaagattaac atctacattt atccatagca
       61 aaaaatcata ggattttaag aatctgacaa ctaggaagaa aactaatatg accttatcta
      121 agaaacaatt acaactacga gctaaaatac tggaaacagt ttacacatta ggtcccattt
      181 cacgaattga aatcgctact aaaacaggaa taacacctgc aacaactagc agtatcacaa
      241 atgatctgat taaagaaaac attctcttag aacttggtga agacgaacac gatacaagcg
      301 tagggagaaa aaaaatcctg ctagacattc aagctaaacg attttactac attggttgtg
      361 aactatctga aaaacatttc acttttgctt taggagataa tctaggaaat atcttaaagg
      421 aagagaaaga aattgttact aaacagttaa tccaagaaaa gggaaatcaa ctcattagcc
      481 agacactaaa gcaattctta aataactgct ctgattatga aatagaagca attggaatcg
      541 cgctacctgg tcgctattta gatgattata aaataacaac aaacaatcct ttatggcaac
      601 atatcgactt agaaatgatt caatcccact ttgataagcc tttgtttttc tctaacaatg
      661 ttaactgtat ggctataggt aaacgcctat ttagtcgcca acagaatgac cctaattttg
      721 cttattttca ttttgctaga ggtatgcact gttcttatat ctacgacgga aacatttatg
      781 gaaaaggaaa tctaatgatt ggagaaatag ggcatacagt tgtttcatct gagggagaag
      841 aatgtagttg cgggcgcaag ggatgcttac aaacttttgc tggagaatct tggttaatca
      901 aaaaatcaaa aattctatat catcaatctc cctattctct acttcctagt ttagtcaaaa
      961 atgccgatga tattgatatc caagttattt taaccgctta tcaattaggt gacactggaa
     1021 taatcacact tatccatcaa gccttactct atcttagtca aaccatttta aatatcagta
     1081 tgatgattga ctctcaaaaa atctacctac atagtccttt actaacaaat caacacatca
     1141 tccaaaaact atatagtgaa atgaactaca aacccaaact gctctataat cgcctacctg
     1201 aagtcattat tgaaccttac aatgatttta cagccgcaca ctcagctatt gcactttgtt
     1261 tgtatcatac aattctacat tcctaatttt ctattacatt taataaatag gctaaaaaga
     1321 gggagtatat cataaaaagc gaacaaacct gttttctgaa aatcagaatt ctgttttgtt
     1381 cgctttcttt atatttggaa ttatactcct atctcccctt tttcataatg tatagtaaaa
     1441 tgaaataata acaggacgaa tcgatc
//
LOCUS       DBEJJV010000091         1128 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.091, whole genome shotgun sequence.
ACCESSION   DBEJJV010000091 DBEJJV010000000
VERSION     DBEJJV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1128
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.091"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            119..>1128
                     /gene="pavB"
                     /locus_tag="ACL3GT_002114"
     CDS             119..>1128
                     /gene="pavB"
                     /locus_tag="ACL3GT_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HGR0517698.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQENPELTDALKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKDNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HV"
BASE COUNT          383 a          208 c          237 g          300 t
ORIGIN      
        1 taatataagt gttttataag agggatttaa gaaaaatttt aactttttct tagtcctttt
       61 taatttcagg agattatact agagtcatca aataaagaaa gactctaagg agaatcctat
      121 gaaattcaat ccaaatcaaa gatatactcg ttggtctatt cgccgtctca gtgtcggtgt
      181 tgcctcagtt gttgtggcta gtggcttctt tgtcctagtt ggtcagccaa gttctgtacg
      241 tgccgatgtg gtcaatccga ccccaggtca agtcttacct gaagagacat cgggaacgaa
      301 agagggtgac ttatcagaaa aaccaggaga caccgttctc actcaagcga aacctgaggg
      361 cgttactgga aatacgaatt cacttccgac acctacagaa agaactgaag tgagcgagga
      421 aacaaactct tctagtctgg atacactttt tgaaaaagat gaagaagctc aagaaaatcc
      481 agagctaaca gatgccttaa aagaaactgt agatacagct gatgtggatg ggacacaagc
      541 aagtccagca gaaactactc ctgaacaagt aaaaggtgga gtgaaagaaa atacaaaaga
      601 cagcatcgat gttcctgctg cttatcttga aaaagctgaa gggaaaggtc ctttcactgc
      661 tggtgtaaac caagtaattc cttatgaact attcgctggt gatggtatgt taactcgtct
      721 attactaaaa gcttcggata atgctccttg gtctgacaat ggtactgcta aaaatcctgc
      781 tttacctcct cttgaaggat taacaaaagg gaaatacttc tatgaagtag acttaaatgg
      841 caatactgtt ggtaaacaag gtcaagcttt aattgatcaa cttcgcgcta atggtactca
      901 aacttataaa gctactgtta aagtttacgg aaataaagac ggtaaagctg acttgactaa
      961 tctagttgct actaaaaatg tagacatcaa catcaatgga ttagttgcta aagaaactgt
     1021 cgaaaaagct gttaaagata acgttaaaga cagtatcgat gttccagcag cctacctaga
     1081 aaaagccaag ggtgaaggtc cattcacagc aggtgtcaac catgtgat
//
LOCUS       DBEJJV010000092         1095 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.092, whole genome shotgun sequence.
ACCESSION   DBEJJV010000092 DBEJJV010000000
VERSION     DBEJJV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.092"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..145)
                     /locus_tag="ACL3GT_002115"
     CDS             complement(<1..145)
                     /locus_tag="ACL3GT_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HGR0517699.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLY"
     gene            complement(157..723)
                     /gene="amaP"
                     /locus_tag="ACL3GT_002116"
     CDS             complement(157..723)
                     /gene="amaP"
                     /locus_tag="ACL3GT_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HGR0517700.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(807..971)
                     /locus_tag="ACL3GT_002117"
     CDS             complement(807..971)
                     /locus_tag="ACL3GT_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HGR0517701.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
BASE COUNT          371 a          216 c          153 g          355 t
ORIGIN      
        1 tatataatcc agctgcaact cccagtgctc ctaaaatcaa tacaaatatt gttttgaaga
       61 agccaaagga gacaatcaaa caagccagaa atacgcctat gagaccagcg ataattggat
      121 atcgatattg tttaagccat tccatttttt acttccttac ttcacacgac taacagtctt
      181 tttgttttga ggttttggtt ggtaattttt tactgcaact tcaagtttta cttgacgctc
      241 aataccaaaa aactgcttca atccattagt tatttcattt tgaattattt ggcatctgtc
      301 agcgatgttg tctgaaggaa gaattttacc ttctacatga acgaaacatt tattttttcg
      361 taaatttaca tgaacagttg ggttcttgat caatctatga tcactcacca aacttctaac
      421 aaaaccttcg attgccgaat tctttaattt taatgtatcg tttttagttt caagttggat
      481 ttccaagtaa cgtttaggat aaaacatcac aactaaaatg gataataaaa ctaaagttga
      541 tagaaccact gtcccccaaa agacatatct agcaagatag aattcaacta cggagttctg
      601 tctccagcta agtagatgaa tacctagatc actaacttga tgataatcta tcaaaacagg
      661 aaggaaaatt gtcaagatta aaatacagaa aataatgaaa catattttct ttgcttttga
      721 catatacaat cctttcgatt taacatttaa actatttttc ccgtcattga tttaaaaata
      781 gtttgctaac tttactggcg aaaagtttac tttctacctg taaagaatga cactacagta
      841 atcacaatcg ctgcacctac aatagatggg agcaaagcca ttccagcgat tgatggaccc
      901 caactaccta aaagagattg tcctgcatat gccccgacta aaccagcgaa tacatttgcg
      961 atgattccca tagaactact tttttagtga ttttacctgc caagagacca ataagacctc
     1021 cagcaataat tgatcacaac actgcctacc ctcctttttt attttaatat caaaaaatca
     1081 atttctttga ttaat
//
LOCUS       DBEJJV010000093         1001 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.093, whole genome shotgun sequence.
ACCESSION   DBEJJV010000093 DBEJJV010000000
VERSION     DBEJJV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.093"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(28..117)
                     /locus_tag="ACL3GT_002118"
     tRNA            complement(28..117)
                     /locus_tag="ACL3GT_002118"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(79..81),aa:Ser,seq:tga)
     gene            complement(128..201)
                     /locus_tag="ACL3GT_002119"
     tRNA            complement(128..201)
                     /locus_tag="ACL3GT_002119"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(165..167),aa:Ile,seq:cat)
     gene            complement(215..288)
                     /locus_tag="ACL3GT_002120"
     tRNA            complement(215..288)
                     /locus_tag="ACL3GT_002120"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(252..254),aa:Met,seq:cat)
     gene            complement(294..367)
                     /locus_tag="ACL3GT_002121"
     tRNA            complement(294..367)
                     /locus_tag="ACL3GT_002121"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(331..333),aa:Pro,seq:tgg)
     gene            complement(383..456)
                     /locus_tag="ACL3GT_002122"
     tRNA            complement(383..456)
                     /locus_tag="ACL3GT_002122"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(420..422),aa:Arg,seq:acg)
     gene            complement(466..551)
                     /locus_tag="ACL3GT_002123"
     tRNA            complement(466..551)
                     /locus_tag="ACL3GT_002123"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(515..517),aa:Leu,seq:taa)
     gene            complement(559..630)
                     /locus_tag="ACL3GT_002124"
     tRNA            complement(559..630)
                     /locus_tag="ACL3GT_002124"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(596..598),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="ACL3GT_002125"
     tRNA            complement(653..725)
                     /locus_tag="ACL3GT_002125"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(744..825)
                     /locus_tag="ACL3GT_002126"
     tRNA            complement(744..825)
                     /locus_tag="ACL3GT_002126"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(789..791),aa:Leu,seq:tag)
     gene            complement(831..903)
                     /locus_tag="ACL3GT_002127"
     tRNA            complement(831..903)
                     /locus_tag="ACL3GT_002127"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(868..870),aa:Lys,seq:ttt)
     gene            complement(928..1000)
                     /locus_tag="ACL3GT_002128"
     tRNA            complement(928..1000)
                     /locus_tag="ACL3GT_002128"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(965..967),aa:Asp,seq:gtc)
BASE COUNT          260 a          291 c          226 g          224 t
ORIGIN      
        1 agctgctcca tcccgcgtta atataaaagg aggatgtggg attcgaaccc acgcacgctt
       61 ttacacgcct gacggttttc aagaccgttc ccttcagccg gacttgggta atcctccaat
      121 attcaaatgg accttgtagg acttgaacct acgaccactc ggttatgagc cgagagctct
      181 aaccagctga gctaaaggtc cgacaagatc attatagcgg cgaaggggat cgaacccccg
      241 acctcccggg tatgaaccgg acgctctagc cagctgagct acaccgccat gaatcgggaa
      301 gacaggattc gaacctgcga caccttggtc ccaaaccaag tactctacca agctgagcta
      361 cttcccgagt taaatagaaa aatgcaccct agaggagtcg aacctctaac cgcctgattc
      421 gtagtcaggt actctatcca gttgagctaa gggtgctcca tattatgccg aggaccggaa
      481 tcgaaccggt acgatcgtta ccaatcgcag gattttaagt cctgtgcgtc tgccagttcc
      541 gccaccccgg cctctctaag cgaacgacgg gattcgaacc cgcgaccccc accttggcaa
      601 ggtggtgttc taccactgaa ctacgttcgc actgttttct tctatctaaa aatgccggct
      661 acatgacttg aacacgcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggctcatt tgttatatct taatgcgggt taagggactt gaacccccac gccgttaagc
      781 gccagatcct aaatctggtg cgtctgccaa ttccgccaaa cccgcatata tgacccgtac
      841 tgggctcgaa ccagtgaccc attgattaaa agtcaattgc tctaccaact gagctaacga
      901 gtctaaaata acttgcgtta tcttaaacgg tcccgacggg aatcgaaccc gcgatcttcg
      961 ccgtgacagg gcgacgtgat aaccgctaca ctacgggacc t
//
LOCUS       DBEJJV010000094          983 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.094, whole genome shotgun sequence.
ACCESSION   DBEJJV010000094 DBEJJV010000000
VERSION     DBEJJV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.094"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            231..706
                     /locus_tag="ACL3GT_002129"
                     /pseudo
     CDS             231..706
                     /locus_tag="ACL3GT_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            744..>983
                     /locus_tag="ACL3GT_002130"
     CDS             744..>983
                     /locus_tag="ACL3GT_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HGR0517702.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEARPILFRI"
BASE COUNT          334 a          156 c          189 g          304 t
ORIGIN      
        1 gtgttttgag taacctgcgg ctagcttcct agtttgctct ttgattttca ttgagtatta
       61 gaacagaaaa atgcttggag tatttgtttg tgtgtttatt tttatataac aaactataaa
      121 cacaacaaaa atataaaaaa agagacaaaa aagaacagaa agtaattaac aacgatttca
      181 tatagtgtta tacttatagc ataaagttaa tggaaagaag ggaaaacctt atggtattag
      241 attatttctt tgacaaaaac cttgtgtttt gcttagaagc ggataatcaa gaataactct
      301 ttgatcaggt agcaagcttg ttggaggaac gagaaattgt aactccaact tatcgtgaag
      361 ctttgatcac gcgtgaaaag tcatttccaa ctggtttaga tatggaattt ctaggaaagg
      421 acttgcaaat gtaatgattc ctcacacaga tattgttcat aatctagctg agaaagtggt
      481 ggttgttcga ttagagaaac cggtgacttt ccataatatg attgcgccag gtaaggaagt
      541 agaagtatcc ttgctcttct ttatcatcaa taattcaagt tcaagtcaaa cgaacattct
      601 tgctcagttg atggactttt tcacaggaaa tggacatctt gaagacctat caaaaatttc
      661 cgaaccagaa aaactttatg cttatataga tgaagcaatc gcttaatctt gtctattaaa
      721 aaataaaatc ggaggaagtc tatatgatta aaattcttgc tgcctgcggt gcaggtgtta
      781 actcaagtca ccaaattaaa agtgctctag aagaagaact ttcaaaccgt ggttacgatg
      841 ttcactgtga tgcagttatg gtgaaagatg taaacgaaga ccttatgaaa ggttacgata
      901 tctttacacc aatcgctgca acagaccttg gttttgaacc aggtatccca gttatcgaag
      961 ctaggccaat cttattccgt atc
//
LOCUS       DBEJJV010000095          924 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.095, whole genome shotgun sequence.
ACCESSION   DBEJJV010000095 DBEJJV010000000
VERSION     DBEJJV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..924
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.095"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>924
                     /locus_tag="ACL3GT_002131"
     CDS             <1..>924
                     /locus_tag="ACL3GT_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HGR0517703.1"
                     /translation="RGLTGAQGAKGEKGDQGERGLTGAQGAKGEKGDQGEQGLQGRDG
                     EQGPKGEDGKNPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEA
                     DKTTTVIFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDN
                     NNGTHTITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSY
                     TAGKDELVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFV
                     KKGNTWEPAGNIKGPKGDKGADGAKGEKGAQG"
BASE COUNT          388 a          153 c          225 g          158 t
ORIGIN      
        1 acgcggtcta accggagcac aaggtgccaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctaaccgga gcacaaggtg ctaaaggtga aaaaggggac caaggtgaac aaggtcttca
      121 agggcgtgat ggtgaacaag gaccaaaagg agaagatggg aaaaacccaa cagttaaagt
      181 aactgatggt caagatggaa cgcatacaat tacaattaac gatggtaaag gtggtataac
      241 tactacagta gtaagagatg gatttgatgg tgcaagccct cttgtttcta ctcatagaaa
      301 tgaagcagat aaaacaacaa ctgttatttt ctattatgat ctaaatgata ataatcaatt
      361 tgatgaagga gatacaaaac ttaaagaagt tgttatcgca gatggaaaac aaggaccaaa
      421 aggtgacaaa ggtgataacg gaaaagatgg attcacacca gaagtaacag ttacagataa
      481 caataacgga acacacacca tcacaatcac acaaccagac aacagaccat cattaacaac
      541 aatcgttaaa aacggtgaag atggaaaaac accaaaagtc aaagcagaac gagatgatgc
      601 gaagaaacaa acaacattaa cattctacat tgacaaagat ggagatggaa gttacacagc
      661 aggaaaagac gagttagttc aaacaacagt agttaaagac ggacaagacg gagctgcagg
      721 agcatctgga cgtgatggaa aagaagtatt aaacggaaaa gtagacccaa caacagaagg
      781 taaagatgga gacacattcg taaatacaca aacaggagat gtattcgtta agaaaggtaa
      841 cacttgggaa ccagcaggaa acatcaaagg accgaaaggt gacaaaggtg cagatggtgc
      901 caagggtgaa aaaggagccc aagg
//
LOCUS       DBEJJV010000096          847 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.096, whole genome shotgun sequence.
ACCESSION   DBEJJV010000096 DBEJJV010000000
VERSION     DBEJJV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.096"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            1..847
                     /locus_tag="ACL3GT_002132"
                     /pseudo
     CDS             1..847
                     /locus_tag="ACL3GT_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          257 a          184 c          139 g          267 t
ORIGIN      
        1 tcgtcaagaa gaatcaccaa atccctcgta ttatcaacca aaaaattgcg caaaagttaa
       61 ttgaaaagat ttctatgacc gatattgccc atcagctttc catctcaact tcaactgtta
      121 ttcgtaagct caatgatttt cactttaaac atgatttttc ttgtcttcct gagattatgt
      181 cttgggatga gtatgctttt acaaagggaa agatgagttt cattgcgcaa gattttgata
      241 atcttaatat tatcactgtt cttgaaggca gaacacaagc tgtcatccga aatcactttc
      301 ttcgctacga tagagccgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagcc
      361 cttactatga cttggctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt
      421 ctcccagact gtttcactcc cgaatgctaa aatcgttctt gatcgctttc acattgtaca
      481 acatcttagc cgtgctatga gtcgtgtgca tgtccaaatc atgaatcagt ttcatcgaaa
      541 atcccatgaa tacaaggcta tcaagcgcta ctggaaactc attcaacagg atagccgtaa
      601 actgagtgat aagcgatttt atcgtcctac ttttcgtatg cacttaacca ataaagagat
      661 tttaaacaag cttttgagct attcggaaga cttgaaacac cactatcagc tctatcagct
      721 cttgcttttt cacttccaga acaaggaacc agagaaattt ttcggactta ttgaggacaa
      781 tcttaagcag gttcatcctc tttttcagac tgtctttaaa accttcctca aagataaaga
      841 aaagatt
//
LOCUS       DBEJJV010000097          802 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.097, whole genome shotgun sequence.
ACCESSION   DBEJJV010000097 DBEJJV010000000
VERSION     DBEJJV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.097"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>802
                     /locus_tag="ACL3GT_002133"
     CDS             <1..>802
                     /locus_tag="ACL3GT_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HGR0517704.1"
                     /translation="IAKLDYDAPSCPECGSQMKKYDFQKPSKIPYLETTGMPTRILLR
                     KRRFKCYHCSKMMVAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLSISTSTV
                     IRKLNDFHFKHDFSRLPEIMSWDEYAFTKGKMSFIAQDFEKLDIITVLEGRTQAIIRN
                     HFLRYDRVVRCRVKIITMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQ
                     IMNQLDRKSHEYKAIKRYWKLIQQDSRKLSDKHFYRPTFRMHLTNKEIF"
BASE COUNT          242 a          169 c          141 g          250 t
ORIGIN      
        1 catcgccaaa ctggactacg acgccccatc ttgccctgag tgcggaagtc aaatgaagaa
       61 atatgacttt caaaaacctt ctaaaattcc ttatcttgaa acgactggta tgcctactag
      121 aattctcctt agaaagcgtc gattcaagtg ctatcactgt tcaaaaatga tggtcgctga
      181 aacttctatc gtcaagaaga atcaccaaat ccctcgtatc atcaaccaaa agattgctca
      241 aaagttaatt gaaaagattt ctatgactga tattgcccat cagctttcca tctcaacttc
      301 aactgttatt cgtaagctca atgattttca ctttaaacat gatttttcgc gtcttcctga
      361 gattatgtct tgggatgagt atgcttttac aaagggaaag atgagcttca ttgcgcaaga
      421 ttttgaaaag ctcgatatca tcactgttct tgagggtaga acacaagcta tcattcgaaa
      481 tcactttctt cgctacgata gagttgtccg atgtcgcgtc aaaattatta ctatggatat
      541 gtttagtcct tactatgact tagctagaca acttttcccg tgtgctaaaa tcgtgttgga
      601 tcgctttcac attgtacaac atcttagccg tgctatgagt cgtgtgcgtg ttcaaatcat
      661 gaatcaattg gatcgaaagt ctcatgaata caaggctatc aagcgctact ggaagctcat
      721 acaacaggat agtcgtaaac tcagcgataa acatttttat cgccctactt ttcgtatgca
      781 tttaaccaat aaagagattt tt
//
LOCUS       DBEJJV010000098          786 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.098, whole genome shotgun sequence.
ACCESSION   DBEJJV010000098 DBEJJV010000000
VERSION     DBEJJV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..786
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.098"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            20..>786
                     /locus_tag="ACL3GT_002134"
     CDS             20..>786
                     /locus_tag="ACL3GT_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HGR0517705.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQF"
BASE COUNT          247 a          165 c          130 g          244 t
ORIGIN      
        1 actcattaga aagaatcata tggaacaatt acattttatc acaaaactgc tcgatattaa
       61 agacccaaac atcaagattc tagatatcat caatatggat acccacaaag aaattatcgc
      121 taagctggat tatgaggctc catcttgccc tgattgtgga agtctaatga agaaatatga
      181 ctttcaaaaa ccgtctaaga tcccttacct cgaaacaact ggtatgcctt ctagaattct
      241 ccttagaaaa cgccgtttca agtgctatca ctgttcaaaa atgatggttg ctgagactcc
      301 cctggtaaag aaaaatcacc aaatccctcg tatcatcaac caaaaaattg ctcaaaagtt
      361 aattgaaaaa atttctatga ctgatattgc ccatcagctg gccatttcaa cttcaactgt
      421 cattcgcaag ctcaatgact ttcactttga gcatgatttt tctcggcttc caaagattat
      481 gtcttgggat gagtatgcct tcactaaggg aaagatgagt ttcattgcgc aagattttga
      541 taatcttaat attatcactg ttcttgaagg cagaacacaa gctgtcatcc gaaatcactt
      601 tcttcgctac gatagagccg ttcgttgtca agtgaaaatc attacgatgg atatgtttag
      661 tccttactat gacttggcta aacagctttt tccgtgtgct aaaatcgttc tagatcgttt
      721 ccatattatc caacatctca gccgtgccat gagtcgtttt cgtgttcaaa ttatgaatca
      781 gtttga
//
LOCUS       DBEJJV010000099          692 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.099, whole genome shotgun sequence.
ACCESSION   DBEJJV010000099 DBEJJV010000000
VERSION     DBEJJV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.099"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            73..692
                     /locus_tag="ACL3GT_002135"
                     /pseudo
     CDS             73..692
                     /locus_tag="ACL3GT_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
BASE COUNT          275 a           85 c          135 g          197 t
ORIGIN      
        1 gttaccaaag gcgatagaag aaaaactatc gtctttttct ttgcaaattt ttaagaaggg
       61 aggtgatctt gcatggactt tgaatatttt tataacagag aagcggaaag atttaacttc
      121 ttaaaagtac cggagatatt agttgataga gaagaatttc ggggcttatc agcagaagca
      181 attatccttt attccatact tcttaaacgg acaggaatgt catttaagaa taactggata
      241 gacaaggaag gcagagtatt tatctatttt actgtcgaag aaattatgaa aagaagaaat
      301 atctcaaagc caactgccat aaaaacatta gatgagcttg atgtaaaaaa aaggaatagg
      361 actgatcgaa agagtaaggc ttggacttgg taagccgaac atcatttatg ttaaagactt
      421 tatgagtata tttcaggtaa aagaaaatga cttacaaaag tcaaaaaact taacttcaga
      481 agtaaaagat tttaacctca gaagtaaaga aaatgaactt caagaggtta agaaccttga
      541 ctctaactat atagagaata ataagagtaa gtatagtaag agagaatata gttttggtga
      601 aaacggactt ggaacatttc aaaatgtgtt tttagctgtt gaagatatat cggatttaca
      661 aatcataatg aactcacagc ttgagaatta ca
//
LOCUS       DBEJJV010000100          632 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.100, whole genome shotgun sequence.
ACCESSION   DBEJJV010000100 DBEJJV010000000
VERSION     DBEJJV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..632
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.100"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..586)
                     /locus_tag="ACL3GT_002136"
     CDS             complement(<1..586)
                     /locus_tag="ACL3GT_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HGR0517706.1"
                     /translation="MKIENESKSYDKCILKNISLEIDKGIYRVEGENGSGKSTLLQLL
                     AGLETFDSGLKNCVSKDVLYLDTNQLGVVPFTIEENLQLLCDSFQIHLSFEDKEQINT
                     FFDNKIGDNYMTASTGTKFKLGLSLIFAKNWDYIFIDETLSTVDARSIDMIAKRLISM
                     KESSTIIYVSHNLLNQELISKSQRILIEEGRVYEI"
BASE COUNT          219 a          114 c           72 g          227 t
ORIGIN      
        1 aaatttcata aacccgtcct tcctctatta aaatcctttg agatttgcta atcaattctt
       61 gattcaataa attatgagat acatatataa tagtagagct ttctttcatg gaaattaagc
      121 gtttagcaat catatcaata cttcttgcat ccactgttga taaagtctca tcaataaaaa
      181 tataatccca atttttagca aaaattaagg ataagcctaa tttgaatttt gttccagtag
      241 atgctgtcat atagttatct ccgattttat tatcaaaaaa agtattaatt tgttctttat
      301 cctcaaatga tagatggatt tgaaaagaat cacacaacaa ctgcaaattt tcttctatag
      361 taaatggaac aaccccaagc tgattggtat caaggtatag tacatctttg gagacacaat
      421 tctttaaacc actatcaaaa gtctctagcc cagctaaaag ttgtagaagg gtgctctttc
      481 ctgaaccatt ctctccttca actctgtaaa ttcccttatc aatctctagt gatatatttt
      541 tcaatataca tttatcataa cttttagatt cattttcaat tttcataatt taattccctc
      601 tatcaacgct gctaaaatta ataaaagata ag
//
LOCUS       DBEJJV010000101          629 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.101, whole genome shotgun sequence.
ACCESSION   DBEJJV010000101 DBEJJV010000000
VERSION     DBEJJV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..629
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.101"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>629
                     /gene="phtB"
                     /locus_tag="ACL3GT_002137"
     CDS             <1..>629
                     /gene="phtB"
                     /locus_tag="ACL3GT_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HGR0517707.1"
                     /translation="LKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQV
                     AKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKE
                     KGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPH
                     YDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGF"
BASE COUNT          200 a          129 c          139 g          161 t
ORIGIN      
        1 actcaaggat gtctcaagtg ataaagtcaa gttagtggat gatattcttg ccttcttagc
       61 tccgattcgt catccagaac gtttaggaaa accaaatgcg caaattacct acactgatga
      121 tgagattcaa gtagccaagt tggcaggcaa gtacacaaca gaagacggtt atatctttga
      181 tcctcgtgat ataaccagtg atgaggggga tgcctatgta actccacata tgacccatag
      241 ccactggatt aaaaaagata gtttgtctga agctgagaga gcggcagccc aggcttatgc
      301 taaagagaaa ggtttgaccc ctccttcgac agaccatcag gattcaggaa atactgaggc
      361 aaaaggagca gaagctatct acaaccgcgt gaaagcagct aagaaggtgc cacttgatcg
      421 tatgccttac aatcttcaat atactgtaga agtcaaaaac ggtagtttaa tcatacctca
      481 ttatgaccat taccataaca tcaaatttga gtggtttgac gaaggccttt atgaggcacc
      541 taaggggtat actcttgagg atcttttggc gactgtcaag tactatgtcg aacatccaaa
      601 cgaacgtccg cattcagata atggttttg
//
LOCUS       DBEJJV010000102          606 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.102, whole genome shotgun sequence.
ACCESSION   DBEJJV010000102 DBEJJV010000000
VERSION     DBEJJV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.102"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            21..383
                     /locus_tag="ACL3GT_002138"
     CDS             21..383
                     /locus_tag="ACL3GT_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HGR0517708.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYPYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          207 a           71 c          111 g          217 t
ORIGIN      
        1 ttttcattga gtataacaca ttgttagaag ttggtttaaa tttcctaatc agtttgttca
       61 catttacctt cgatatatta tatcccatag ttaaggttgg tcatacagat gattatagcc
      121 atggagccgt aaaacttagt gtttctttag ttgacaaaga tgccatgaaa aaaatatctg
      181 taactgtaat aggatatttt gaaataaata tagatgaaaa tatcaccgat attctatacg
      241 taaatggtac tgctattctt tatccttatt tacgttctat tgtttcaata gtttcggcaa
      301 ttgatagcag tgaagcaatg ttgctaccta ccattaatgt tttagagtta ctagataaat
      361 ctcaaccttt tgaagaagaa taatttatta gctcactaaa ttgagggtaa ggaaaagtaa
      421 aagcagtaag aaaaatgtct tgcattatac agcaactttt tgggaatgag tagatggatt
      481 gaataaaatt tgattaagag tggatgattt atctgtagat tattattgga cagttagtct
      541 tgaagtagtc taagaattag gttataatca gtagaagcct tgctaataat gaggaggtta
      601 gtttat
//
LOCUS       DBEJJV010000103          596 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.103, whole genome shotgun sequence.
ACCESSION   DBEJJV010000103 DBEJJV010000000
VERSION     DBEJJV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..596
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.103"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..>596
                     /locus_tag="ACL3GT_002139"
     CDS             <1..>596
                     /locus_tag="ACL3GT_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HGR0517709.1"
                     /translation="LQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKIL
                     HYHKQKFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNF
                     KPAGKSIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKT
                     AESVNQALTLLLGEHRILSITADNGSEFKRLSEVFPEE"
BASE COUNT          205 a          107 c          122 g          162 t
ORIGIN      
        1 tttacaacaa gtgagaaaag ggctatacaa aaaggtctat tctgccgatt acgcacaaac
       61 tgtttaccaa ttcaatcgaa aacggtcggt gaaaaagtta attttaacaa aggaaatcag
      121 agagaagatc ttacactatc ataagcaaaa attttcgcct gaaatgatgg ttaacaagaa
      181 gcaagtgaaa gttggtattt caaccatcta ctactggttt cataatggtc atttaggatt
      241 gacgaaggcc gacatgcttt atcccagaaa aaggaaaggt gtcaagaagc aagctagtcc
      301 gaactttaag ccggcaggta aatctatcga agaacgtcct gacgttatta atcttcgctt
      361 ggaaaatggt cattatgaaa ttgataccgt cctactgact aagataaaaa attattgcct
      421 gttagtctta accgaccggc ggagtagaca ccaaattata aggttaattc caaataaaac
      481 tgctgaatct gtcaatcagg cgcttacgtt actattaggg gagcatcgta ttctgtccat
      541 tactgcagat aatggttcgg agttcaaacg attgtctgag gtatttcctg aggaac
//
LOCUS       DBEJJV010000104          592 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.104, whole genome shotgun sequence.
ACCESSION   DBEJJV010000104 DBEJJV010000000
VERSION     DBEJJV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.104"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            82..561
                     /locus_tag="ACL3GT_002140"
     CDS             82..561
                     /locus_tag="ACL3GT_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HGR0517710.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          228 a           76 c          137 g          151 t
ORIGIN      
        1 ggagctaaag ggaacagaat ggagaaaatg gaacaaatgt gttttctaat ctgttagact
       61 gtatctagaa aggggaaaat tatgattaaa gaattgtatg aagaagtcca agggactgtg
      121 tataagtgta gaaatgaata ttaccttcat ttatgggaat tatcggattg ggaccaagaa
      181 ggcatgctct gcttacatga attgattagt agagaagaag gactggtaga cgatattcca
      241 cgtttaagga aatatttcaa aaccaagttt cgaaatcgaa ttttagacta tatccgtaag
      301 caggaaagtc agaagcgtag atacgataaa gaaccctatg aagaagtggg tgagatcagt
      361 catcgtataa gtgagggggg tctctggcta gatgattatt atctctttca tgaaacacta
      421 agagattata gaaacaaaca aagtaaagag aaacaagaag aactagaacg cgtcttaagc
      481 aatgaacgat ttcgagggcg tcaaagagta ttaagagact tacgcattgt gtttaaggag
      541 tttactatcc gtacccacta gtaagtcatg caaaaaaaaa tgaaaaaaat ta
//
LOCUS       DBEJJV010000105          575 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.105, whole genome shotgun sequence.
ACCESSION   DBEJJV010000105 DBEJJV010000000
VERSION     DBEJJV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.105"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(1..575)
                     /locus_tag="ACL3GT_002141"
                     /pseudo
     CDS             complement(1..575)
                     /locus_tag="ACL3GT_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          176 a           98 c          126 g          175 t
ORIGIN      
        1 cttttcttta tctttgagga aggttttaaa gacagtctga aaaataggat gaacctgctt
       61 aagattgtcc tcgataagtc cgaaaaattt ctctggttcc ttattctgga agtgaaaaag
      121 caagagctga tagagctgat agtgatgttt caagtcttgt gaatagctca aaagtttgtc
      181 taaaatctct ttattggtta aatgcatacg aaaagtagga cgataaaatc gcttatcact
      241 cagtttacgg ctatcctgtt gtatgagttt ccagtagcgc ttgatagcct tgtattcatg
      301 gaactttcga tccaattgat tcatgatttg aacacgcaca cgactcatag cacggctaag
      361 atgttgcaca atgtgaaagc gatcaagaac gattttagca ttcgggagtg aaacagtctg
      421 ggagactgtt tcagcctgag cctagaaatt tgaaagcgaa gctgtttagc caagtcatag
      481 taagggctaa acatatccat agtaataatt ttgacgcgac atcggacagc tctatcgtag
      541 cgaagaaagt gatttcgaat gatagcttgt gttct
//
LOCUS       DBEJJV010000106          429 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.106, whole genome shotgun sequence.
ACCESSION   DBEJJV010000106 DBEJJV010000000
VERSION     DBEJJV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.106"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            complement(<1..248)
                     /locus_tag="ACL3GT_002142"
     CDS             complement(<1..248)
                     /locus_tag="ACL3GT_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HGR0517711.1"
                     /translation="MAYSIDFRKKVFSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKPRKVDRDRLKNYLTDNPDAYLTEIAS"
     gene            complement(356..429)
                     /locus_tag="ACL3GT_002143"
     tRNA            complement(356..429)
                     /locus_tag="ACL3GT_002143"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(393..395),aa:Asn,seq:gtt)
BASE COUNT          130 a           83 c           67 g          149 t
ORIGIN      
        1 tcagaagcta tttcagtcaa ataagcgtct ggattgtcag taagatagtt tttaagtcta
       61 tctctatcaa cctttcttgg ttttgttcct tttacttggt ggtttagctc tcctgttttc
      121 tcttttagct ttaaccagcc ataaatggta ttacgtgaga tttggaaaac gtgtgacgct
      181 tctgttatac tacctgttcg ctcacaataa gagaaaactt ttttacgaaa atctattgaa
      241 tatgccataa aaagattata ccacattgtg tactattttt ggttcatttt actataacac
      301 aaaatagatt attattacat aacaaaaaag aggtctaaac ctcttaactc aattactccg
      361 ccagtaggac tcgaacctac gacatcatga ttaacagtca tgcgctacta ccaactgagc
      421 tatggcgga
//
LOCUS       DBEJJV010000107          378 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.107, whole genome shotgun sequence.
ACCESSION   DBEJJV010000107 DBEJJV010000000
VERSION     DBEJJV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..378
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.107"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            <1..110
                     /locus_tag="ACL3GT_002144"
     CDS             <1..110
                     /locus_tag="ACL3GT_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HGR0517712.1"
                     /translation="VSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWENC"
BASE COUNT          111 a           47 c           89 g          131 t
ORIGIN      
        1 tagtatctgt tcaagttgac gaaacagatg aagttgatgg aatgcgattt agtacattca
       61 gtacaaaccg ttgcggtaac tggagtgctt ttagttggga aaattgttaa ttcatttaaa
      121 ttgtaaactt tagggattct ctgaagttat ggatgtcgtt ccaatatgtg tacgttggaa
      181 tgttagtgct tatatggggg gaacagaatc ctctcttgat tgaagacaag ttagccatta
      241 ggctggtttg tctctttgtc aactgtagtg ggttgatata atagtattag tgagtgggat
      301 aaaagtttca tttagtttat tcagtacaaa tttaacgggt caagatttat tgaactgcac
      361 cccaatagtt agacagaa
//
LOCUS       DBEJJV010000108          345 bp    DNA     linear   BCT 22-JAN-2025
DEFINITION  TPA_asm: Streptococcus pneumoniae strain GPSC16 isolate 678507
            SAMN38261800-rid24806633.denovo.108, whole genome shotgun sequence.
ACCESSION   DBEJJV010000108 DBEJJV010000000
VERSION     DBEJJV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN38261800
            Sequence Read Archive: SRR26833683
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1  (bases 1 to 345)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 345)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JAN-2025) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 18-JAN-2025
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002576067.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002576067.1
            Genome Coverage       :: 259x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/18/2025 23:21:15
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 2,145
            CDSs (total)                      :: 2,104
            Genes (coding)                    :: 1,970
            CDSs (with protein)               :: 1,970
            Genes (RNA)                       :: 41
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 35
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 134
            CDSs (without protein)            :: 134
            Pseudo Genes (ambiguous residues) :: 0 of 134
            Pseudo Genes (frameshifted)       :: 65 of 134
            Pseudo Genes (incomplete)         :: 62 of 134
            Pseudo Genes (internal stop)      :: 51 of 134
            Pseudo Genes (multiple problems)  :: 37 of 134
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN38261800-rid24806633.denovo.108"
                     /strain="GPSC16"
                     /isolate="678507"
                     /isolation_source="hospital"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /geo_loc_name="United Kingdom"
                     /collection_date="2019"
                     /collected_by="UKHSA"
     gene            231..>345
                     /locus_tag="ACL3GT_002145"
     CDS             231..>345
                     /locus_tag="ACL3GT_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HGR0517713.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLG"
BASE COUNT          118 a           53 c           78 g           96 t
ORIGIN      
        1 taccttagtc aagaattaga tgtttcacta tgtttgagta agttgatgat ttcatttgat
       61 aacaggtttg aaactgttag gctaggtggc caaggctaat catagccttg gtttagctga
      121 aaaaacaggt tcaagggttc ctgttgtcaa atgaaatgtg atttaaggta taagaaaaca
      181 cctctgtgct atacttgttg ttcaccacaa acacaaggaa aggcacagag atgcaagaac
      241 attatacccc aaaagggaaa catttgacaa tagataaccg tcgcttgatt gagcggtgga
      301 agaatgaaaa taagtccaat cgtgaaattg caggcttgtt aggaa
//
